October

The kinase evolution section has been enhanced with an analysis of kinase evolution throughout eukaryotes, detailing the birth, expansion, and death of kinases in major eukaryotic lineages.

September

The kinome analysis of the sea urchin (Strongylocentrotus purpuratus) illustrates a key point in the evolution of vertebrates. We found that the urchin contains kinases belonging to almost every human class, with minimal redundancy, and may offer a key model for understanding vertebrate signaling.

August

Tetrahymena kinome released. This is the most anciently-diverged kinome yet, and has a huge array (over 1000) of kinases, with agreat deal of novelty and sheds light on ancient kinase conservation.
 

April

Our new analysis of the kinome of the slime mold Dictyostelium discoideum has been published in PLoS Genetics. Paper and supporting data are available through our Dictyostelium page, and through the KinBase database.
 

February

The KinBase search page now includes the ability to search for particular domains within kinases.
 

January

View domain diagrams for every kinase through KinBase. Each kinase report now includes diagram of the Pfam domain layout, and the search page also has a button to display domains for any number of kinases.

2005

December

Our updated analysis of the C. elegans kinome, including a preliminary analysis of the C. briggsae kinome has now been published in the WormBook encyclopedia. See the C. elegans page for details.