Databases available for BLAST search
Peptide Sequence Databases
- 4-kinome proteins
- Protein sequences of protein kinases and protein kinase pseudogenes from the four genomes of Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster and human.
- 4-kinome kinase domains
- Eukaryotic protein kinase domains extracted from the 4-kinome proteins database above. Proteins with dual kinase domains have separate entries for each domain.
- 5-kinome proteins
- 5-kinome kinase domains
- These add the Dictyostelium kinome to the previous set of 4 kinomes. Due to the large amount of repetitive sequence in Dicty kinases, you may wish to turn on the filter option to increase speed when searching against these databases.
DNA Sequence Databases
- Human Kinome cDNAs
- Predicted cDNA sequences of the 518 human protein kinases and 106 human protein kinase pseudogenes. An 'NNN' motif in a pseudogene sequence represents the editing of a frameshift, giving rise to an X in the peptide sequence, and suppressing the frameshift in genomic sequence.
About the format
The title of each sequence consists of its most common name, followed by additional data: the species (Sc = yeast; Ddis = Dictostelium; Ce = worm; Dm = fly; Hs = human), the internal Sugen accession number if it has one, and the classification (Group/Family[/Subfamily]).