C. elegans Phosphoprotein Signaling Molecules and Cyclins

# Sequence Superfamily Group Family Description - Alt clones aa Domains
1 M02A10.3 PP-BD - SH2 Adapter CBL/SLI-1 SLI-1_ce; Similar to Proto-oncogene c-CBL 582 SH2, Ring
2 F39B2.5 PP-BD - SH2 Adapter CIS4/SOCS5   268 SH2, SOCS
3 Y41D4A_3457.b PP-BD - SH2 Adapter CRK   373 SH2, SH3
4 ZK470.5 PP-BD - SH2 Adapter NCK2   443 SH3, SH3, SH3, SH2
5 C14F5.5 PP-BD - SH2 Adapter SEM5/GRB2 SEM5_CAEEL; Sex muscle abnormal protein 5 228 SH2, SH2, SH3
6 F54A5.3A PP-BD - SH2 Adapter SHC F54A5.b 334 PTB, SH2
7 C35B8.2 PP-BD - SH2 GEF VAV U23520   860 CH, RhoGEF, PH, SH2
8 B0207.11 PP-BD - SH2 Other B0207.11_ce   273 SH2
9 F44F4.10 PP-BD - SH2 Other B0207.11_ce   280 SH2
10 T08G11.2 PP-BD - SH2 Other B0207.11_ce   282 SH2
11 Y81G3A.1 PP-BD - SH2 Other B0207.11_ce   243 SH2
12 T04A8.14 PP-BD - SH2 Other EMB5/SPT6_sc EMB5_ce; EMB-5 PROTEIN 1521 S1, SH2
13 Y37D8A.4 PP-BD - SH2 Other PLCg2-like   227 SH2
14 C48G7.2 PP-BD - SH2 Other RIN1   474 SH2
15 B0273.3 PP-BD - SH2 Other SNAP50_h   424 SH2
16 F58E6.1 PP-BD - SH2 Other STAT5   809 CC, DNA-BD, SH2
17 Y51H4 PP-BD - SH2 Other STAT Y43D4   SH2
18 M01E11.7a PP-BD - SH2 Other Tensin   1110 SH2, PTB
19 F54E2.4 PP-BD - SH2 Other Titin   472 Ig-C2, SH2
20 C18A11.4 PP-BD - SH2 Other Unique   190 SH2
21 K11E4.2 PP-BD - SH2 Other Unique   226 SH2
22 R10H10.7 PP-BD - SH2 Other Unique   1416 SH2
23 YK27E9.5 PP-BD - SH2 Other Unique T27F7.2 732 PTB, SH2
24 Y87G2A.a PP-BD - SH2 Other VAV-like   156 SH2
25 C04F6.1 PP-BD - SH2 Other VIT5   1602 SH2, VWD
26 F59D8.b PP-BD - SH2 Other VIT5   1703 SH2, VWD
27 T01E8.3 PP-BD - SH2 PLCg PLCg1 Dual SH2 domains 1299 PLC-X, PH, SH2, SH2, SH3, PH, PLC-Y, C2
28 F59G1.5 PP-BD - SH2 PTP SHP2 Dual SH2 domains 827 SH2, SH2, PTP
29 M79.1 PP-BD - SH2 TK ABL ABL_ce; Tyrosine protein kinase ABL-1 1196 SH3, SH2, TK
30 Y48G1B_55.a PP-BD - SH2 TK CSK   1693 SH3, SH2, TK
31 C34F11.5 PP-BD - SH2 TK CTK   893 SH2, TK
32 B0523.1 PP-BD - SH2 TK FER YKF1_ce 408 SH2, TK
33 C18H7.4 PP-BD - SH2 TK FER   445 SH2, TK
34 C25A8.5 PP-BD - SH2 TK FER   415 SH2, TK
35 C35E7.10a PP-BD - SH2 TK FER   430 SH2, TK
36 C55C3.4 PP-BD - SH2 TK FER   430 SH2, TK
37 F01D4.3 PP-BD - SH2 TK FER   399 SH2, TK
38 F22B3.8 PP-BD - SH2 TK FER   484 SH2, TK
39 F22D6.1 PP-BD - SH2 TK FER   418 SH2, TK
40 F23C8.7 PP-BD - SH2 TK FER F23C8.e 417 SH2, TK
41 F26E4.5 PP-BD - SH2 TK FER   379 SH2, TK
42 F44E5.2 PP-BD - SH2 TK FER   819 SH2, TK
43 F46F5.2 PP-BD - SH2 TK FER   381 SH2, TK
44 F53G12.6 PP-BD - SH2 TK FER   492 SH2, TK
45 F57B9.8 PP-BD - SH2 TK FER   459 SH2, TK
46 F59A3.8 PP-BD - SH2 TK FER   584 SH2, TK
47 K07F5.4 PP-BD - SH2 TK FER   517 SH2, TK
48 K09B11.5 PP-BD - SH2 TK FER   588 SH2, TK
49 M142 PP-BD - SH2 TK FER     SH2, TK
50 M176.9 PP-BD - SH2 TK FER   478 SH2, TK
51 R05H5.4 PP-BD - SH2 TK FER   414 SH2, TK
52 R11E3.1 PP-BD - SH2 TK FER   545 SH2, TK
53 T04B2.2 PP-BD - SH2 TK FER   390 SH2, TK
54 T06C10.3 PP-BD - SH2 TK FER   556 SH2, TK
55 T06C10.6 PP-BD - SH2 TK FER   432 SH2, TK
56 T13H10.1 PP-BD - SH2 TK FER KIN-5 533 SH2, TK
57 T21G5.1 PP-BD - SH2 TK FER   578 SH2, TK
58 T25B9.4 PP-BD - SH2 TK FER   546 SH2, TK
59 T25B9.5 PP-BD - SH2 TK FER   541 SH2, TK
60 W01B6.5 PP-BD - SH2 TK FER   553 SH2, TK
61 W02A2.4 PP-BD - SH2 TK FER W02A2.d 500 SH2, TK
62 W03A5.1 PP-BD - SH2 TK FER   513 SH2, TK
63 W03F8.2 PP-BD - SH2 TK FER   617 SH2, TK
64 W08D2.8 PP-BD - SH2 TK FER   534 SH2, TK
65 Y116A8_02435.1 PP-BD - SH2 TK FER     SH2, TK
66 Y116A8_02435.2 PP-BD - SH2 TK FER     SH2, TK
67 Y4C6A.k PP-BD - SH2 TK FER   489 SH2, TK
68 Y69E1A.3 PP-BD - SH2 TK FER Y69E1A.c 563 SH2, TK
69 ZC581.7 PP-BD - SH2 TK FER   416 SH2, TK
70 ZK593.9 PP-BD - SH2 TK FER   529 SH2, TK
71 ZK622.1 PP-BD - SH2 TK FER   418 SH2, TK
72 Y47G6A_245.h PP-BD - SH2 TK FRK   661 SH3, SH2, TK
73 F49B2.5 PP-BD - SH2 TK FYN   496 SH3, SH2, TK
74 Y43C5B.2 PP-BD - SH2 TK xFrag-TK   245 SH2, TK
               
# Sequence Superfamily Group Family Description - Alt clones aa Domains
1 F52D10.3 Phosphoprotein BD 14-3-3 14-3-3 sp|Q20655|1434_CAEEL ftt-2    
2 M117.2 Phosphoprotein BD 14-3-3 14-3-3 sp|P41932|1433_CAEEL ftt-1    
3 M117.3 Phosphoprotein BD 14-3-3 14-3-3      
               
# Sequence Superfamily Group Family Description - Alt clones aa Domains
1 H09G03.2 Phosphoprotein BD WW WW   691 1 PDZ, 1 B41
2 Y40B1A.2 Phosphoprotein BD WW WW   120  
3 C29F3.5 Phosphoprotein BD WW WW   179  
4 H02K04.1 Phosphoprotein BD WW WW   260 2 WW domains
5 C43E11.3 Phosphoprotein BD WW WW Y74A11.Contig318; Y48F5.Contig110 1590 1 SET
6 T10H10.3 Phosphoprotein BD WW WW   241 2 WW domains
7 F45H7.6 Phosphoprotein BD WW WW   889 2 WW, 1 HECTc
8 F13E6.4 Phosphoprotein BD WW WW   457  
9 K01A6.1 Phosphoprotein BD WW WW   1012 5 PDZ domains
10 ZK1127.9 Phosphoprotein BD WW WW   946 3 WW domains
11 ZK1248.15 Phosphoprotein BD WW WW   652  
12 ZK1098.1 Phosphoprotein BD WW WW YO61_CAEEL 724 2 WW domains
13 C38D4.5 Phosphoprotein BD WW WW YLE5_CAEEL 837 1 PH, 1 RhoGAP
14 Y65B4A_125.A Phosphoprotein BD WW WW     3 WW domains
15 T21D12.3 Phosphoprotein BD WW WW   297  
16 Y110A2A_12682.C Phosphoprotein BD WW WW Y110A2A_12685.C    
17 Y65B4.Contig192 Phosphoprotein BD WW WW     5 WW
18 Y92H12.Contig304 Phosphoprotein BD WW WW     2 WW
19 Y92H12.Contig303 Phosphoprotein BD WW WW      
20 C29F3.4 Phosphoprotein BD WW WW   189  
21 F16H6.2 Phosphoprotein BD WW WW   148  
22 C56G7 Phosphoprotein BD WW WW      
               
# Sequence Superfamily Group Family Description - Alt clones aa Domains
1 M4.1 Phosphoprotein BD FHA FHA AAC68994; Y67D8C_397.D 449  
2 T08D2.E Phosphoprotein BD FHA FHA T08D2.7; CAB07420; Y60A3.ctg05073; T08D2.J 1080 STK
3 B0511.7 Phosphoprotein BD FHA FHA   349  
4 YK110H1.3 Phosphoprotein BD FHA FHA C32E8.5 299  
5 C44B9.4 Phosphoprotein BD FHA FHA   1204 2 PHD Zn finger
6 F56E3.3 Phosphoprotein BD FHA FHA C15C7 1576  
7 UNC-104 Phosphoprotein BD FHA FHA U104_CAEEL C52E12.2 1584 1 kinesin, 1 PH, 3 Coiled coil
8 ZK632.2 Phosphoprotein BD FHA FHA YOT2_CAEEL 710 1 DSRM (dsRNABD)
9 C01G6.5 Phosphoprotein BD FHA FHA YKI5_CAEEL 952  
10 Y23H5.Contig16 Phosphoprotein BD FHA FHA C32E8.5-like; Y74C10.Contig122    
11 Y60A3A Phosphoprotein BD FHA FHA T08D2.7 -like; Y116F11.ctg01677    
               
# Sequence Superfamily Group Family Description - Alt clones aa Domains
1 F54D12.6 Phosphoprotein BD PTB PTB SNT2-like (FGFR adapter) 44/150 (29%); Y51H7.Contig288 195  
2 F54A5.B Phosphoprotein BD PTB PTB SHC-like; Y34D9.Contig160; F54A5.3A 334 PTB, SH2
3 T03D8.1A Phosphoprotein BD PTB PTB CAB07405 593  
4 C09H6.2 Phosphoprotein BD PTB PTB LIN-10; X11_m (P98084) 262/568 (46%) 982 PTB, PDZ, PDZ
5 F56D2.7 Phosphoprotein BD PTB PTB CED-6; p67_m (U18869) 103/450 (22%) 492  
6 M01E11.7A Phosphoprotein BD PTB PTB related to sp|Q04205|TENS_CHICK 157/284 (55%) 1110 SH2, PTB
7 F35H12.2 Phosphoprotein BD PTB PTB GAPCenA-like (AJ011679) 1142 PTB, TBC
8 F52D10.2 Phosphoprotein BD PTB PTB   329  
9 M110.5 Phosphoprotein BD PTB PTB   547  
10 M88.4 Phosphoprotein BD PTB PTB   349  
11 YK27F7.2 Phosphoprotein BD PTB PTB   732 PTB, SH2
12 C11E4.6 Phosphoprotein BD PTB PTB   1125 ANK, SAM, PTB?
13 Y57G11C.24C Phosphoprotein BD PTB PTB EPS8-like 929 PTB, SH3
14 Y57G11C.24A Phosphoprotein BD PTB PTB EPS8-like 732  
15 C13A10.3 Phosphoprotein BD PTB PTB IB1/JIP1-like (AAD20443); Y51H7.Contig288 315 SH3, PTB
16 C54D1.3 Phosphoprotein BD PTB PTB IRS1-like 1163 PH, PTB
               
# Sequence Superfamily Group Family Description - Alt clones aa Domains
1 W09H1.1 Phosphatase DSP STYX Y48C3 - very weak - no HCSAG 403  
2 Y34B4.Contig105 Phosphatase DSP SBF1 Y34B4A - No HCXD    
3 H28G03.6 Phosphatase DSP SBF1   443  
               
# Sequence Superfamily Group Family Description - Alt clones aa Domains
1 ZK507.6 CYCLIN CYCLIN CycA sp|P34638|CG2A_CAEEL; Cyclin A1    
2 ZK678.3 CYCLIN CYCLIN CycA CAB01905.1    
3 W05G11.2 CYCLIN CYCLIN CycA      
4 T24A6.1 CYCLIN CYCLIN CycA      
5 C02B8.1 CYCLIN CYCLIN CycA      
6 W02F12 CYCLIN CYCLIN CycA      
7 F27D4 CYCLIN CYCLIN CycA      
8 ZK1225 CYCLIN CYCLIN CycA      
9 F59H6.G CYCLIN CYCLIN CycA fragment-extend    
10 C03B8.2 CYCLIN CYCLIN CycA fragment-extend    
11 C04C3.4 CYCLIN CYCLIN CycA fragment-extend    
12 T07F10.5 CYCLIN CYCLIN CycA fragment-extend    
13 W01H2 CYCLIN CYCLIN CycA fragment-extend    
14 W02A11 CYCLIN CYCLIN CycA Y18D10.ctg02173 fragment-extend    
15 F23H12 CYCLIN CYCLIN CycA fragment-extend    
16 F08F1.9 CYCLIN CYCLIN CycA      
17 F59H6.F CYCLIN CYCLIN CycA Y16E11.contig94    
18 ZC168.4 CYCLIN CYCLIN CycB CYCLIN B; sp|Q10653|CG2B_CAEEL    
19 T06E6.2 CYCLIN CYCLIN CycB CYCLIN B3; CE13315; sp|Q10654|CGB3_CAEEL    
20 Y43E12A.1 CYCLIN CYCLIN CycB Y48F5.contig109    
21 Y38F1.F CYCLIN CYCLIN CycD cyclin d    
22 C37A2.4 CYCLIN CYCLIN CycE cyclin E    
23 R02F2.1 CYCLIN CYCLIN CycI      
24 Y102A5C.F CYCLIN CYCLIN CycI fragment-extend    
25 F43D2.1 CYCLIN CYCLIN CycK/T similarity to human g1/s-specific cyclin c    
26 F44B9.3 CYCLIN CYCLIN CycK/T      
27 F44B9.4 CYCLIN CYCLIN CycK/T      
28 C52E4.6A CYCLIN CYCLIN CycK/T      
29 C52E4.6B CYCLIN CYCLIN CycK/T      
30 H14E04.5 CYCLIN CYCLIN CycK/T H14E04.A    
31 W03D2.4 CYCLIN CYCLIN PCNA sp|O02115|PCNA_CAEEL; F35F11    
32 Y49F6B.R CYCLIN CYCLIN CycH Y49F6B_108.I strong similarity to CycH_dm    
33 T12C9.4 CYCLIN CYCLIN Unique      
34 ZK353.1 CYCLIN CYCLIN Unique ZK353.1 weak similarity to TXNL_h [thioredoxin-like]    

Last Updated on 11/23/1999
By Greg Plowman