# Sequence ACC# Superfamily Group Family Specificity Description   ACC#        
1 SCH9 AAB69735 Protein kinase AGC AKT SCH9/KOM1/YHR205W Serine/threonine protein kinase that is activated by cAMP, overproduction can suppress cdc25 mutant. AAB69735
2 YBR028C CAA84970 Protein kinase AGC AKT YBR028C/YBR0312 Serine/threonine protein kinase with similarity to Ypk2p/Ykr2p and Ypk1p. CAA84970
3 YPK1 CAA81967 Protein kinase AGC AKT YPK1/YKL126W Serine/threonine protein kinase with similarity to protein kinase C. CAA81967
4 YPK2 CAA89740 Protein kinase AGC AKT YPK2/YKR2/YM9718.03/YMR104C Serine/threonine protein kinase with similarity to Ypk1p. CAA89740
5 CBK1 CAA96048 Protein kinase AGC NDR CBK1/N1727/YNL161W Putative serine/threonine protein kinase of unknown function. CAA96048
6 DBF2 CAA97095 Protein kinase AGC NDR DBF2/G4643/YGR092W  Serine/threonine protein kinase Similar to Dbf20p, required for events in anaphase/telophase. CAA97095
7 DBF20 AAB05204 Protein kinase AGC NDR DBF20/P8283.6/YPR111W  Cell cycle protein kinase Similar to Dbf2p, involved in termination of M-phase. AAB05204
8 TPK1 CAA89459 Protein kinase AGC PKA TPK1/PKA1/SRA3/PK25/J0541/YJL164C cAMP-dependent protein kinase 1, catalytic chain. CAA89459
9 TPK2 CAA97917 Protein kinase AGC PKA TPK2/PKA2/YKR1/P1855/YPL203W/PKA3 cAMP-dependent protein kinase 2, catalytic chain. CAA97917
10 TPK3 CAA82008 Protein kinase AGC PKA TPK3/PKA3/YKL630/YKL166C cAMP-dependent protein kinase 3, catalytic chain. CAA82008
11 YDR466W AAB64902 Protein kinase AGC PKA-Related Yeast YDR466W/D8035.10 Serine/threonine protein kinase of unknown function. AAB64902
12 YDR490C AAB64917 Protein kinase AGC PKA-Related Yeast YDR490C/D8035.33/PKH1 Serine/threonine protein kinase functions similarly to mammalian 3-phosphoinositide-dependent protein kinase; phosphorylates and activates Ypk1p AAB64917
13 YOL100W CAA99113 Protein kinase AGC PKA-Related Yeast YOL100W/HRC1081/O0784/PKH2 Serine/threonine protein kinase of unknown function. CAA99113
14 PKC1 CAA84932 Protein kinase AGC PKC PKC1/STT1/HPO2/CLY15/YBL0807/YBL105C Protein kinase C, regulates MAP kinase cascade involved in regulating cell wall metabolism. CAA84932
15 RIM15 CAA04486 Protein kinase AGC RIM15/CEK1 Yeast RIM15; YFL033C Serine/threonine protein kinase; positive regulator of IME2 expression and of sporulation CAA04486
16 KIN82 CAA42256 Protein kinase AGC S6K KIN82/YCR1153/YCR091W Serine/threonine protein kinase of unknown function. CAA42256
17 YNR047W CAA96328 Protein kinase AGC S6K YNR047W/N3449 Serine/threonine protein kinase of unknown function. CAA96328
18 TWF1 CAA97082 Protein kinase Atypical PK A6 TWF1; G4583; YGR080W Protein with similarity to human tyrosine kinase A6 PIR:A55922.  Not in alignment. CAA97082
19 SLN1 P39928 Protein kinase Atypical PK Hist PK SLN1; YPD2; NRP2; YIL147C Two-component signal transducer involved in the high-osmolarity MAP kinase signal transduction pathway;initiates a phosphorelay from Sln1p to Ypd1p to Ssk1p P39928
20 YGL059W CAA96762 Protein kinase Atypical PK PDK YGL059W/YGF9  Protein with similarity to human branched-chain alpha-ketoacid dehydrogenase kinase CAA96762
21 YIL042C P40530 Protein kinase Atypical PK PDK YIL042C/YIE2/YI9905.06c  Related to mitochondrial branched-chain a-ketoacid (BCKD) and pyruvate dehydrogenase (PDH) kinases, which are protein-serine kinases P40530
22 KIN1 CAA88675 Protein kinase CAMK AMPK KIN1/YD9727.17/YDR122W  Serine/threonine protein kinase, Similar to Kin2p and S. pombe KIN1. CAA88675
23 KIN2 CAA97659 Protein kinase CAMK AMPK KIN2/L8004.3/L2546/YLR096W  Serine/threonine protein kinase, Similar to Kin1p and S. pombe KIN1. CAA97659
24 KIN4 CAA99453 Protein kinase CAMK AMPK KIN4/KIN31/(KIN3)/O5220/YOR233W Serine/threonine protein kinase Similar to Kin1p and Kin2p, catalytic domain is most Similar to Snf1p. CAA99453
25 SNF1 AAB64904 Protein kinase CAMK AMPK SNF1/CAT1/CCR1/PAS14/HAF3/D8035.20/YDR477W  Serine/threonine protein kinase essential for derepression of glucose-repressed genes, acts with Snf4p. AAB64904
26 YPL141C AAB68219 Protein kinase CAMK AMPK YPL141C/LPI5 Serine/threonine protein kinase with similarity to Kin4p. AAB68219
27 YPL150W CAA97855 Protein kinase CAMK AMPK YPL150W/P2597 Serine/threonine protein kinase of unknown function. (Not in YPD listing) CAA97855
28 CMK1 BAA09253 Protein kinase CAMK CAMK CMK1/YFR014C Calcium/calmodulin-dependent serine/threonine protein kinase (CaM kinase), type I. BAA09253
29 CMK2 CAA99015 Protein kinase CAMK CAMK CMK2/O2325/YOL016C  Calcium/calmodulin-dependent serine/threonine protein kinase (CaM kinase), type II. CAA99015
30 DUN1 CAA98668 Protein kinase CAMK CAMK DUN1/ORF2370/YDL101C Protein kinase necessary for induction of Rnr3p and DNA repair genes after DNA damage.  Contains FHA domain. CAA98668
31 RCK1 CAA96870 Protein kinase CAMK CAMK RCK1/G1854/YGL158W  Serine/threonine protein kinase with similarity to Cmk1p, Cmk2p, and Cmk3p. (Seq updated) CAA96870
32 RCK2 AAB67392 Protein kinase CAMK CAMK RCK2/CMK3/CLK1/L9672.6/YLR248W  Calcium/calmodulin-dependent serine/threonine protein kinase (CaM kinase). AAB67392
33 SPK1 CAA97858 Protein kinase CAMK CHK2 SPK1/RAD53/MEC2/SAD1/P2588/YPL153C Serine/threonine/tyrosine protein kinase with a checkpoint function in S and G2. Contains FHA domain.  (Similar to CDS1_sp) CAA97858
34 ELM1 CAA81883 Protein kinase CAMK ELM Yeast ELM1/YKL261/YKL048C Serine/threonine protein kinase regulating pseudohyphal growth. CAA81883
35 PAK1 AAC03227 Protein kinase CAMK ELM Yeast PAK1/SYGP-ORF45/YER129W Protein kinase capable of suppressing DNA polymerase alpha mutations. AAC03227
36 YGL179C CAA96762 Protein kinase CAMK ELM Yeast YGL179C/BIE560/G1618 Serine/threonine protein kinase with similarity toElm1p and Kin82p. CAA96762
37 GIN4 AAB64949 Protein kinase CAMK EMK/GIN4 GIN4/D9719.13/YDR507C Serine/threonine-protein kinase with similarity to Yc1024p, growth inhibitory protein. AAB64949
38 HSL1 CAA81941 Protein kinase CAMK EMK/GIN4 HSL1/YKL453/YKL101W Serine/threonine protein kinase that interacts genetically with histone mutations. CAA81941
39 YCL024W CAA42361 Protein kinase CAMK EMK/GIN4 YCL024W Protein with similarity to Snf1p. CAA42361
40 MEK1 CAA99680 Protein kinase CAMK Other MEK1/MRE4/O6357/YOR351C  Serine/threonine protein kinase required for meiotic recombination.  Contains forkhead-associated (FHA) nuclear signalling domian. CAA99680
41 YMR291W CAA56800 Protein kinase CAMK Other YMR291W/ORF530348 Serine/threonine protein kinase of unknown function. CAA56800
42 YKL116C CAA81955 Protein kinase CAMK/EMK Unique Yeast YKL116C/YKL516 Serine/threonine protein kinase with similarity to S pombe nim1. (33% Identity to p78_h) CAA81955
43 HRR25 CAA97918 Protein kinase CKI CKI HRR25/P1850/YPL204W Casein kinase I, serine/threonine/tyrosine protein kinase, associated with DNA repair and meiosis. CAA97918
44 YCK1 AAB68417 Protein kinase CKI CKI YCK1/CKI2/YHR135C Casein kinase I isoform. AAB68417
45 YCK2 CAA96041 Protein kinase CKI CKI YCK2/(CKI1)/(CKI)/N1755/YNL154C Casein kinase I isoform. CAA96041
46 YCK3 AAC03221 Protein kinase CKI CKI YCK3/CKI3/YER123W Casein kinase I isoform. AAC03221
47 CAK1 BAA09209 Protein kinase CMGC CDK CAK1/CIV1/YFL029C Cdk-activating kinase (serine/threonine protein kinase) responsible for in vivo activation of Cdc28p.  PHNAKFE in kinase domain III. BAA09209
48 CDC28 CAA85119 Protein kinase CMGC CDK CDC28/CDK1/SRM5/HSL5/YBR1211/YBR160W Cyclin-dependent protein kinase essential for completion of START and for mitosis, associates with Cks1p and cyclins.  PSTAIRE in kinase domain III. CAA85119
49 KIN28 CAA98675 Protein kinase CMGC CDK KIN28/ORF2330/YDL108W CDK component of transcription initiation factor TFIIH, phosphorylates C-terminal domain (CTD) of RNA polymerase large subunit.  DMSAIRE in kinase domain III. CAA98675
50 PHO85 AAB68188 Protein kinase CMGC CDK PHO85/P7102_18A/YPL031C Cyclin-dependent protein kinase that interacts with cyclin Pho80p to regulate phosphate pathway.  PSTAIRE in kinase domain III. AAB68188
51 SSN3 AAB68178 Protein kinase CMGC CDK SSN3/UME5/SRB10/(ARE1)/P7102_08/YPL042C  CDK of the RNA polymerase II holoenzyme complex and Kornberg's mediator (SRB) subcomplex.  SQSACRE and TLY in kinase domains III and VIII. AAB68178
52 IME2 CAA89401 Protein kinase CMGC CLK IME2/SME1/J0817/YJL106W STK and positive regulator of sporulation genes that is essential for initiation of meiosis. TAY in kinase domain VIII (activation loop).  (Similar to MAK_r, p34_h, CDK2_h) CAA89401
53 KNS1 CAA97468 Protein kinase CMGC CLK KNS1/L1224/YLL019C Serine/threonine protein kinase of unknown function.  (Similar to CLK_h) CAA97468
54 YAK1 CAA89437 Protein kinase CMGC CLK YAK1/YJL141C Serine/threonine protein kinase that suppresses loss of Tpk1p + Tpk2p + Tpk3p.  (Similar to KA23_sp, MNB_dm, MNB_h) CAA89437
55 YMR216C CAA89931 Protein kinase CMGC CLK YMR216C/YM8261.10 Putative serine/threonine protein kinase, involved in phosphorylation of Npl3p, similar to Cdc31p.  (Similar to DSK1_sp, SRPK1_ce, U52111_h). CAA89931
56 MCK1 CAA96236 Protein kinase CMGC GSK MCK1/(YPK1)/N0392/YNL307C Serine/threonine/tyrosine protein kinase (meiosis and centromere regulatory kinase), positive regulator of meiosis and spore formation. CAA96236
57 MDS1 CAA87353 Protein kinase CMGC GSK MDS1/RIM11/GSK3/YM9375.08/YMR139W Serine/threonine protein kinase, required for induction of IME2 by Ime1p, homolog of mammalian GSK3. CAA87353
58 MRK1 CAA98645 Protein kinase CMGC GSK MRK1/D2459/D2461/YDL079C Serine/threonine protein kinase with similarity to Mds1p. CAA98645
59 YOL128C CAA99147 Protein kinase CMGC GSK YOL128C/O0530/ORF1209713 Protein serine/threonine protein kinase of unknown function. CAA99147
60 FUS3 CAA84835 Protein kinase CMGC MAPK FUS3/DAC2/YBL0303/YBL03.21/YBL016W Serine/threonine protein kinase of the MAP kinase family required for cell cycle arrest and for cell fusion during mating.  TEY in kinase domain VIII. CAA84835
61 HOG1 CAA97680 Protein kinase CMGC MAPK HOG1/SSK3/L9354.2/L2931/YLR113W Serine/threonine protein kinase of MAP kinase (MAPK) family, involved in high-osmolarity signal transduction pathway.  TGY in kinase domain VIII. CAA97680
62 KSS1 CAA97038 Protein kinase CMGC MAPK KSS1/G4149/YGR040W Serine/threonine protein kinase of the MAP kinase family, redundant with Fus3p for cell cycle arrest.  TEY in kinase domain VIII (activation loop). CAA97038
63 SLT2 AAB68912 Protein kinase CMGC MAPK SLT2/MPK1/SLK2/BYC2/YHR030C Serine/threonine protein kinase of MAP kinase family involved in the cell wall integrity pathway.  TEY in kinase domain VIII. AAB68912
64 SMK1 CAA89172 Protein kinase CMGC MAPK SMK1/YP9499.10/YPR048W Sporulation-specific MAP kinase required for completion of sporulation.  TNY in kinase domain VIII. CAA89172
65 YKL161C CAA82003 Protein kinase CMGC MAPK YKL161C/YKL615 Serine/threonine protein kinase of unknown function.  KGY in kinase domain VIII. CAA82003
66 CTK1 CAA81980 Protein kinase CMGC Other CTK1/YKL139W Carboxyl-terminal domain (CTD) kinase alpha subunit, CDK that phosphorylates C-terminal domain of RNA polymerase II large subunit.  PITSIRE in kinase domain III. CAA81980
67 SGV1 AAB68058 Protein kinase CMGC Other SGV1/BUR1/P9584.8/YPR161C Serine/threonine protein kinase involved in pheromone adaptation pathway and in cell cycle.  PITAQRE in kinase domain III. AAB68058
68 ABC1 CAA96827 Protein kinase Microbial PK ABC1_sc ABC1; G2920; YGL119W  Protein likely to be involved in assembly of ubiquinol cytochrome-c reductase complex CAA96827
69 YLR253W AAB67388 Protein kinase Microbial PK ABC1_sc YLR253W/L9672.2/YL53 Protein with weak similarity to Abc1p AAB67388
70 YPL109C AAB68252 Protein kinase Microbial PK ABC1_sc YPL109C; LPH17  Protein of unknown function AAB68252
71 RI01 CAA99317 Protein kinase Microbial PK RI01_sc RIO1; YOR3266; O3266; YOR119C  Protein of unknown function CAA99317
72 YNL207W CAA96109 Protein kinase Microbial PK RI01_sc YNL207W; N1342  Protein of unknown function CAA96109
73 YGR262C CAA97291 Protein kinase Microbial PK YGR262_sc YGR262C/G9334 Protein with similarity to apple tree calcium/calmodulin-binding protein kinase PIR:JQ2251. CAA97291
74 IPL1 CAA97924 Protein kinase Other AUR IPL1/P1820/YPL209C Serine/threonine protein kinase involved in chromosome segregation. (Similar to AUR_dm) CAA97924
75 BUB1 CAA97214 Protein kinase Other BUB BUB1/G7542/YGR188C Serine/threonine protein kinase and checkpoint protein required for cell cycle arrest in response to loss of microtubule function.  (N-terminus Similar to MAD3_sc) CAA97214
76 YBR274W CAA85237 Protein kinase Other CHK1 YBR274W/YBR1742/CHK1 Checkpoint kinase, required for metaphase DNA-damage checkpo (Similar to CHK1-sp, CHK1_ce, SNF1_r) CAA85237
77 CDC7 CAA98574 Protein kinase Other CKII CDC7/SAS1/OAF2/D2855/YDL017W Protein kinase required for initiation of DNA synthesis, for commitment to sporulation, for DNA repair, and for meiotic recombination.  (Similar to HSK1_sp) CAA98574
78 CKA1 P15790 Protein kinase Other CKII CKA1/YIL035C Casein kinase II, catalytic (alpha) subunit. P15790
79 CKA2 CAA99254 Protein kinase Other CKII CKA2/O2810/YOR061W Casein kinase II, catalytic (alpha) subunit. CAA99254
80 GCN2 AAB64461 Protein kinase Other EIFK GCN2/AAS1/D9954.16/YDR283C Serine/threonine protein kinase that regulates initiation of translation by phosphoryation of eIF2alpha (Sui2p)  (Similar to EIF2aK_r, HRI_r) AAB64461
81 IRE1 AAB68894 Protein kinase Other IRE IRE1/ERN1/YHR079C Protein kinase and type I membrane protein involved in signal transduction from ER lumen to nucleus, part of the unfolded protein response.  (Similar to C41C4.4_ce) AAB68894
82 HAL5 CAA89460 Protein kinase Other NPR/HAL5 Yeast HAL5/J0531/YJL165C Serine/threonine protein kinase involved in salt and pH tolerance. CAA89460
83 NPR1 CAA96076 Protein kinase Other NPR/HAL5 Yeast NPR1/N1631/YNL183C Serine/threonine protein kinase involved in regulating transport systems for nitrogen nutrients under conditions of nitrogen catabolite derepression. CAA96076
84 PTK1 CAA82043 Protein kinase Other NPR/HAL5 Yeast PTK1/YKL198C/STK1/KKT8/(POT1) Serine/threonine protein kinase activator of low-affinity, low-capacity polyamine transport  (Frame shift corrected) CAA82043
85 SAT4 CAA42325 Protein kinase Other NPR/HAL5 Yeast SAT4/YCR101/YCR046/YCR008W Protein with similarity to Npr1p protein kinase. CAA42325
86 YDL025C CAA98584 Protein kinase Other NPR/HAL5 Yeast YDL025C/D2810 Protein with similarity to protein kinase Npr1p. CAA98584
87 YDL214C CAA98792 Protein kinase Other NPR/HAL5 Yeast YDL214C/D1014 Serine/threonine protein kinase with similarity Npr1. CAA98792
88 YJR059W CAA89587 Protein kinase Other NPR/HAL5 Yeast YJR059W/J1725/PTK2/STK2 Putative serine/threonine protein kinase required for high-affinity polyamine transport CAA89587
89 YKL168C CAA82010 Protein kinase Other NPR/HAL5 Yeast YKL168C/YKL632/KKQ8 Serine/threonine protein kinase of unknown function. CAA82010
90 YOR267C CAA99490 Protein kinase Other NPR/HAL5 Yeast YOR267C/O5420 Serine/threonine kinase protein kinase with similarity to Npr1p. CAA99490
91 YAL017W AAC04940 Protein kinase Other PIM YAL017W/YAL002/FUN31 Serine/threonine protein kinase of unknown function. AAC04940
92 YOL045W CAA99051 Protein kinase Other PIM YOL045W/02034/YOL044W Serine/threonine protein kinase of unknown function. CAA99051
93 CDC5 CAA88516 Protein kinase Other PLK CDC5/PKX2/MSD2/YM8270.03/YMR001C Serine/threonine protein kinase required for exit from mitosis, ts mutants block after nuclear division. (Similar to PLK-1_h, POLO_dm) CAA88516
94 KSP1 AAB68896 Protein kinase Other RAN Yeast KSP1/YHR082C Serine/threonine kinase, has similarity to casein kinase II and other serine/threonine protein kinases. AAB68896
95 SHA3 AAB68161 Protein kinase Other RAN Yeast SHA3/SKS1/LPB5/YPL026C Serine/threonine protein kinase that suppresses the growth defect of snf3 mutants on low glucose AAB68161
96 YDR247W CAA89733 Protein kinase Other RAN Yeast YDR247W/YD8419.14 Serine/threonine protein kinase with similarity to S. pombe RAN1 negative regulator of sexual conjugation and meiosis. CAA89733
97 SCY1 CAA96788 Protein kinase Other SCY1_sc SCY1/G3197/YGL083W  Protein involved in suppression of a GTPase mutant CAA96788
98 MPS1 CAA98587 Protein kinase Other TTK MPS1/RPK1/D2785/YDL028C Serine/threonine/tyrosine protein kinase involved in spindle pole body duplication   (Similar to ESK_m, TTK_h). CAA98587
99 YGL180W CAA96892 Protein kinase Other UNC YGL180W/G1615/APG1/AUT3 Serine/threonine protein kinase involved in induction of autophagy after nutrient limitation  (Similar to UNC-51_ce, PLO1_sp) CAA96892
100 VPS15 CAA85050 Protein kinase Other VPS15_sc VPS15/VPT15/(VPL19)/YBR0825/YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting.  (Similar to ZK930.1_ce) CAA85050
101 SWE1 CAA89482 Protein kinase Other WEE SWE1/J0406/YJL187C Serine/tyrosine dual-specificity protein kinase able to phosphorylate Cdc28p on tyrosine and inhibit its activity.  (Similar to Wee1_sp, and MLK_h) CAA89482
102 YBR059C CAA85002 Protein kinase Other YNL020C_sc sc, ce YBR059C/YBR0419 Serine/threonine protein kinase of unknown function. CAA85002
103 YIL095W P40494 Protein kinase Other YNL020C_sc sc, ce YIL095W/(PAK1)/PRK1 Serine/threonine protein kinase involved in regulation of actin cytoskeleton organization P40494
104 YNL020C CAA95882 Protein kinase Other YNL020C_sc sc, ce YNL020C/N2823/ARK1 Serine/threonine protein kinase with probable involvement in cytoskeletal function CAA95882
105 YPL236C CAA97954 Protein kinase Other YPL236_sc YPL236C/P1057  Protein of unknown function. - No GXG (Similar to C3H1.13_sp) (Not in YPD) CAA97954
106 KIN3 AAC04964 Protein kinase STE NEK KIN3/NPK1/FUN52/YAR018C Serine/threonine protein kinase, null mutation has no phenotype.  TTY in kinase domain VIII (activation loop). AAC04964
107 BCK1 CAA89389 Protein kinase STE STE11 BCK1/(SLK1)/SSP31/LAS3/SAP3/J0906/YJL095W Serine/threonine protein kinase of the MEKK family, involved in the cell wall integrity pathway. CAA89389
108 SSK2 CAA96311 Protein kinase STE STE11 SSK2/N3276/YNR031C Map kinase kinase kinase of the high osmolarity signal transduction pathway. CAA96311
109 SSK22 CAA42271 Protein kinase STE STE11 SSK22/YCR073C Map kinase kinase kinase with strong similarity to Ssk2p, participates in the high osmolarity signal transduction pathway. CAA42271
110 STE11 CAA37522 Protein kinase STE STE11 STE11/L8039.10/YLR362W Serine/threonine protein kinase of the MEKK family, component of the pheromone pathway and a pathway regulating filamentous growth. CAA37522
111 CDC15 AAC04965 Protein kinase STE STE20 CDC15/YAR019C Protein kinase of the MAP kinase kinase kinase family essential for late nuclear division.  (Similar to MESS1_m, CDC7_sp, MST1_h) AAC04965
112 CLA4 CAA96216 Protein kinase STE STE20 CLA4/ERC10/N0450/YNL0450/YNL298W Serine/threonine protein kinase required for cytokinesis, has similarity to Ste20p. CAA96216
113 NRK1 AAB68860 Protein kinase STE STE20 NRK1/KIC1/H8263.14/YHR102W Serine/threonine protein kinase that interacts with Cdc31p. AAB68860
114 SPS1 AAB64963 Protein kinase STE STE20 SPS1/D9719.27/YDR523C Serine/threonine protein kinase involved in middle/late stage of meiosis. AAB64963
115 STE20 AAB69747 Protein kinase STE STE20 STE20/YHL007C Serine/threonine protein kinase of the pheromone pathway, also participates in pathway regulating filamentous growth. AAB69747
116 YOL113W CAA99132 Protein kinase STE STE20 YOL113W/HRA655/O0722/SKM1 Serine/threonine protein kinase with similarity to Ste20p. CAA99132
117 MKK1 CAA99451 Protein kinase STE STE7 MKK1/SSP32/O5095/YOR231W Serine/threonine protein kinase of the MAP kinase kinase (MEK) family involved in cell wall integrity pathway. CAA99451
118 MKK2 AAB68220 Protein kinase STE STE7 MKK2/SSP33/LPI6/YPL140C Serine/threonine protein kinase of the MAP kinase kinase (MEK) family involved in cell wall integrity pathway. (Sequence updated) AAB68220
119 PBS2 CAA89423 Protein kinase STE STE7 PBS2/HOG4/SFS4/SSK4/OSR1/J0699/YJL128C Tyrosine protein kinase of the MAP kinase kinase (MEK kinase) family, essential component of the high-osmolarity signal transduction pathway. CAA89423
120 STE7 CAA98732 Protein kinase STE STE7 STE7/D1525/YDL159W Serine/threonine/tyrosine protein kinase of MAP kinase kinase (MEK) family, component of the pheromone pathway and a pathway regulating filamentous growth. CAA98732
121 IKS1 CAA89348 Protein kinase Yeast PK Unique Yeast IKS1/J1143/YJL057C Probable serine/threonine protein kinase CAA89348
122 YGR052W CAA97052 Protein kinase Yeast PK Unique Yeast YGR052W/G4329  Protein of unknown function. (Similar to none) CAA97052
123 YKL171W CAA82013 Protein kinase Yeast PK Unique Yeast YKL171W/YKL635 Serine/threonine protein kinase of unknown function. (Similar to none) CAA82013
124 YPR106W AAB68076 Protein kinase Yeast PK Unique Yeast YPR106W/P8283.9/ISR1 Protein with similarity to protein kinases Gcn2p, galactosyltransferase-associated protein kinase P58/Gtap, and the Raf proto-oncogene. (Similar to none) AAB68076
               
# Sequence   Superfamily Group Family Specificity Description ACC#          
1 CKI1 CAA97704 Protein kinase-like Choline K CKI1 CKI1; (CKI); L3130; L9606.8; YLR133W; KICH  Choline kinase, first step in CDP-choline biosynthesis pathway CAA97704
2 EKI1 CAA90370 Protein kinase-like Choline K CKI1 EKI1; YD8358.04; YDR147W  Ethanolamine kinase I; has similarity to Cki1p choline kinase CAA90370
3 LCB4 CAA99378 Protein kinase-like DAG kin DAGK LCB4; O3615; YOR171C  Long chain base kinase, involved in biosynthesis of sphingolipid CAA99378
4 LCB5 AAB67377 Protein kinase-like DAG kin DAGK LCB5; L8479.7; YLR260W  Long chain base kinase, involved in biosynthesis of sphingolipid AAB67377
5 GUK1 AAB64881 Protein kinase-like GCyc GCyc GUK1/D9461.39/YDR454C Guanylate kinase. AAB64881
6 MEC1 CAA85094 Protein kinase-like Inositol Kinase ATM MEC1/ESR1/SAD3/YBR1012/YBR136W Checkpoint protein required for mitotic growth, DNA repair and mitotic recombination (PI kinase homolog). CAA85094
7 TEL1 CAA84909 Protein kinase-like Inositol Kinase ATM TEL1/YBL0706/YBL088C Protein involved in controlling telomere length, may have posphatidylinositol 3-kinase or protein kinase activity. CAA84909
8 YHR099W AAB68923 Protein kinase-like Inositol Kinase ATM YHR099W/TRA1 Protein with weak similarity to Tor1p and Tor2p, possilbe phosphatidylinositol kinase (PI kinase) homolog. AAB68923
9 TOR1 CAA89594 Protein kinase-like Inositol Kinase PI3K TOR1/DRR1/J1803/YJR066W Phosphatidylinositol kinase(PI kinase) homolog involved in cell growth and sensitivity to the immunosuppressant rapamycin. CAA89594
10 TOR2 CAA82048 Protein kinase-like Inositol Kinase PI3K TOR2/DRR2/YKL203C Phosphatidylinositol kinase(PI kinase) homolog involved in cell growth and sensitivity to the immunosuppressant rapamycin, Similar to Tor1p. CAA82048
11 VPS34 AAB67396 Protein kinase-like Inositol Kinase PI3K VPS34/VPT29/(VPL7)/END12/L9672.10/YKR240W Phosphatidylinositol 3-kinase required for vacuolar protein sorting, activated by protein kinase Vps15p. AAB67396
12 PIK1 CAA96174 Protein kinase-like Inositol Kinase PI4K PIK1/PIK41/PIK120/N0795/YNL267W Phosphatidylinositol 4-kinase, generates PtdIns 4-P. CAA96174
13 STT4 AAB67358 Protein kinase-like Inositol Kinase PI4K STT4/L2142.4/YLR305C Phosphatidylinositol-4-kinase, mutants are staurosporine-sensitive and suppressible by overexpression of Pkc1p. AAB67358
14 FAB1 BAA09258 Protein kinase-like Inositol Kinase PI5K FAB1; SVL7; YFR019W Phosphatidylinositol-3-phosphate 5-kinase involved in orientation or separation of mitotic chromosomes BAA09258
15 MSS4 CAA92347 Protein kinase-like Inositol Kinase PI5K MSS4; TSC15; YD8142A.05; YD8142.05; YDR208W Phosphatidylinositol-4-phosphate 5-kinase; required for proper organization of the actin cytoskeleton CAA92347
                 
# Sequence   Superfamily Group Family Specificity Description ACC#          
1 PHO11 AAC09508 Phosphatase DSP Acid PP PHO11; YAR071W  Acid phosphatase, secreted AAC09508
2 PHO12 AAB69729 Phosphatase DSP Acid PP PHO12; PHO10; H9177.3; YHR215W  Acid phosphatase, secreted AAB69729
3 PHO3 CAA85045 Phosphatase DSP Acid PP PHO3; YBR0813; YBR092C  Acid phosphatase, constitutive, thiamine-binding protein of the periplasmic space CAA85045
4 PHO5 CAA85046 Phosphatase DSP Acid PP PHO5; YBR0814; YBR093C  Acid phosphatase, repressible, requires glycosylation for activity CAA85046
5 YDL024C CAA98583 Phosphatase DSP Acid PP YDL024C/D2815 Protein with similarity to acid phosphatases CAA98583
6 SER2 CAA97235 Phosphatase DSP Atypical SER2; LST3; PSP; G7744; YGR208W Phosphoserine phosphatase; involved in synthesis of serine from 3-phosphoglycerate,  PSP_h 63/198aa (32%) CAA97235
7 CDC14 BAA09267 Phosphatase DSP CDC14 CDC14; OAF3; YFR028C  Dual specificity protein phosphatase (PTPase) that performs a function late in the cell cycle BAA09267
8 MIH1 AAA57223 Phosphatase DSP CDC25 MIH1; YM9973.10; YM9532.01; YMR036C  M-phase inducing protein tyrosine phosphatase (PTPase), dephosphorylates Cdc28p to activate kinase activity AAA57223
9 LTP1 CAA89190 Phosphatase DSP LMW LTP1; YP9499.28; YPR073C  Protein tyrosine phosphatase (PTPase) with similarity to a phosphatase from bovine heart and human placenta; ACP1_h  67/158aa (42%) CAA89190
10 MSG5 CAA95922 Phosphatase DSP MKP MSG5; YNL1629; YNL2480; N2480; YNL053W  Dual-specificity protein tyrosine phosphatase (PTPase); involved in adaptation response to pheromone CAA95922
11 PPS1 CAA85239 Phosphatase DSP MKP PPS1; YBR2013; YBR276C  Protein tyrosine phosphatase (PTPase) with dual specificity CAA85239
12 YIL113w P40479 Phosphatase DSP MKP YIL113W   Dual-specificity protein phosphatase P40479
13 YVH1 Q02256 Phosphatase DSP MKP YVH1; YIR026C Dual-specificity protein phosphatase (PTPase) with similarity to vaccinia VH1 Q02256
14 YJR110w CAA89640 Phosphatase DSP MTM YJR110W; J2007  Protein tyrosine phosphatase (PTPase) of unknown function CAA89640
15 TEP1  CAA96010 Phosphatase DSP PTEN TEP1; N1220; N1872; YNL128W  Protein tyrosine phosphatase (PTPase); has similarity to human tumor suppressor gene TEP1/MMAC/PTEN1  CAA96010
16 PTP1 CAA98809 Phosphatase PTP cPTP PTP1; D0815; YDL230W  Protein tyrosine phosphatase CAA98809
17 PTP2 CAA99423 Phosphatase PTP cPTP PTP2; O4849; YOR208W  Protein tyrosine phosphatase (PTPase); involved in Hog1p MAP kinase high-osmolarity sensing pathway and Fus3p MAP kinase pheromone response pathway CAA99423
18 PTP3 AAB64614 Phosphatase PTP cPTP PTP3/YER075C  Protein tyrosine phosphatase (PTPase) involved in Hog1p MAP kinase high-osmolarity sensing pathway AAB64614
19 GLC7 AAC03231 Phosphatase STP PP1 GLC7; CID1; DIS2; DIS2S1; YER133W  Protein serine/threonine phosphatase PP1; required for glucose repression, member of the PPP family of protein phosphatases AAC03231
20 PPZ1 CAA89936 Phosphatase STP PP1 PPZ1; YM9571.02; YML016C  Protein serine/threonine phosphatase required for normal osmoregulation, member of the PPP family of protein phosphatases and related to PP1 phosphatases CAA89936
21 PPZ2 AAB64859 Phosphatase STP PP1 PPZ2; D9461.22; YDR436W  Protein serine/threonine phosphatase involved in osmoregulation, member of the PPP family of protein phosphatases and related to PP1 phosphatases AAB64859
22 SAL6 CAA97886 Phosphatase STP PP1 SAL6; PPQ1; P2247; YPL179W  Protein serine/threonine phosphatase involved in regulation of protein synthesis; member of the PPP family of protein phosphatases and related to PP1 phosphatases CAA97886
23 PPG1 CAA96312 Phosphatase STP PP2A PPG1; PPG; N3281; YNR032W  Protein serine/threonine phosphatase involved in glycogen accumulation, member of the PPP family of protein phosphatases and related to PP2A phosphatases CAA96312
24 PPH21 CAA98707 Phosphatase STP PP2A PPH21; D2180; YDL134C  Protein serine/threonine phosphatase PP2A-1, homologous to Pph22p; member of the PPP family of protein phosphatases CAA98707
25 PPH22 CAA98765 Phosphatase STP PP2A PPH22; PPH2ALPHA; D1271; YDL188C  Protein serine/threonine phosphatase PP2A-2, highly homologous to Pph21p, member of the PPP family of protein phosphatases CAA98765
26 PPH3 CAA86797 Phosphatase STP PP2A PPH3/D4421/YD8554.08/YDR075W Protein serine/threonine phosphatase, member of the PPP family of protein phosphatases and related to PP2A phosphatases CAA86797
27 SIT4 CAA98609 Phosphatase STP PP2A SIT4; PPH1; D2693; YDL047W  Protein serine/threonine phosphatase involved in cell cycle regulation; member of the PPP family of protein phosphatases and related to PP2A phosphatase CAA98609
28 YNL217W CAA96119 Phosphatase STP PP2A YNL217W; N1306  Protein of unknown function CAA96119
29 CMP2 CAA86718 Phosphatase STP PP2B CMP2; CNA2; (TSM4572); YM9958.05; YML057W   Calcineurin catalytic (A) subunit, protein serine/threonine phosphatase 2B (PP2B) member of the PPP family of protein phosphatases CAA86718
30 CNA1 AAB67518 Phosphatase STP PP2B CNA1; CMP1; L9753.6; YLR433C  Calcineurin catalytic (A) subunit, protein serine/threonine phosphatase 2B (PP2B), member of the PPP family of protein phosphatases AAB67518
31 PTC1 CAA98562 Phosphatase STP PP2C PTC1; TPD1; CWH47; KCS2; D2925; YDL006W  Protein serine/threonine phosphatase of the PP2C family; involved in the dephosphorylation of multiple MAP kinases and involved in tRNA splicing CAA98562
32 PTC2 AAB64644 Phosphatase STP PP2C PTC2; YER089C  Protein serine/threonine phosphatase of the PP2C family AAB64644
33 PTC3 CAA84876 Phosphatase STP PP2C PTC3; (YBL0511); YBL0513; YBL056W  Protein serine/threonine phosphatase of the PP2C family CAA84876
34 YBR125C CAA85082 Phosphatase STP PP2C YBR125C/YBR0921/PTC4 Serine/threonine protein phosphatase of the PP2C family CAA85082
35 PTC5 CAA99287 Phosphatase STP PP2C PTC5; O3157; YOR3157; YOR090C Protein with similarity to serine/threonine protein phosphatases CAA99287
36 YCR079W CAA42267 Phosphatase STP PP2C YCR079W  Protein phosphatase of the PP2C family CAA42267
37 PPT1 CAA97134 Phosphatase STP PP5 PPT1; G6347; YGR123C  Protein serine/threonine phosphatase of unknown function, member of the PPP family of protein phosphatases and related to PP5 phosphatases, has tetratricopeptide (TPR) repeats CAA97134
               
# Sequence   Superfamily Group Family Specificity Description ACC#          
1 LPP1 AAB64945 Phosphatase IPP PPAP LPP1; D9719.9; YDR503C  Lipid phosphate phosphatase, Mg2+-independent AAB64945
2 DPP1 AAB64475 Phosphatase IPP PPAP DPP1/D9819.10/YDR284C Diacylglycerol pyrophosphate phosphatase AAB64475
3 INP52 CAA95982 Phosphatase IPP SHIP INP52; (PIE3); SJH2; SJL2; N2160; YNL106C; YNK6  Inositol polyphosphate-5-phosphatase CAA95982
4 INP53 CAA99307 Phosphatase IPP SHIP INP53; SJL3; PIE2; (SOP2); YOR3231; O3231; YOR109W  Inositol polyphosphate 5-phosphatase CAA99307
5 INP51 P40559 Phosphatase IPP SHIP INP51; SJH1; SJL1; (PIE3); YIA2; INP5; YIL002C  Inositol polyphosphate-5-phosphatase P40559
6 INP54 CAA99075 Phosphatase IPP SHIP INP54; O1175; YOL065C   Inositol polyphosphate-5-phosphatase CAA99075
               
# Sequence   Superfamily Group Family Specificity Description ACC#          
1 SPT6 CAA97124 Phosphoprotein BD SH2 SPT6 SPT6; SSN20; CRE2; G6169; YGR116W  Protein involved in chromatin structure that influences expression of many genes CAA97124
2 BMH1 AAB64704 Phosphoprotein BD 14-3-3 14-3-3 BMH1; APR6; YER177W  Homolog of mammalian 14-3-3 protein, has strong similarity to Bmh2p AAB64704
3 BMH2 CAA87675 Phosphoprotein BD 14-3-3 14-3-3 BMH2/SCD3/YD8557.08/YDR099W Homolog of mammalian 14-3-3 protein, has strong similarity to Bmh1p CAA87675
4 PRP40 CAA81847 Phosphoprotein BD WW WW PRP40; YKL165; YKL012W  U1 snRNA-associated protein required for pre-mRNA splicing CAA81847
5 TIN1 CAA96943 Phosphoprotein BD WW WW TIN1; G0958; YGL227W; YGX7 TOR inhibitory protein CAA96943
6 YFL010C BAA09228 Phosphoprotein BD WW WW YFL010C/YFB0  Protein of unknown function BAA09228
7 ESS1 CAA89541 Phosphoprotein BD WW WW ESS1; PTF1; YJR017C; J1452 Peptidylpropyl-cis/trans-isomerase; involved in transcription termination or 3'-end processing of pre-mRNA CAA89541
8 YPR152C AAB68289 Phosphoprotein BD WW WW YPR152C; P9659.21; Q06525  Protein with similarity to Ykl012p AAB68289
9 SIW14 CAA95895 Phosphoprotein BD PTP STYX SIW14; N2746; YNL032W; YND2  Protein tyrosine phosphatase (PTPase) involved in nutritional control of the cell cycle CAA95895
10 YCR095C CAA42250 Phosphoprotein BD PTP STYX YCR095C/YCR131/YCY5   Protein of unknown function CAA42250
11 YDR067c CAA89096 Phosphoprotein BD PTP STYX YDR067C; YD9609.21; D4264  Protein of unknown function CAA89096
12 YNL056w CAA95929 Phosphoprotein BD PTP STYX YNL056W; YNL2439; N2439; YNF6  Protein with homology to Siw14p and Ynl099cp protein tyrosine phosphatases (PTP's) and which may compete with PTP's for substrates CAA95929
13 YNL099c CAA95975 Phosphoprotein BD PTP STYX YNL099C; N2194; YNJ9  Protein with homology to protein tyrosine phosphatases (PTP's) CAA95975
14 YDR501w AAB64943 Phosphoprotein BD FHA FHA Ydr501w; Q04383; D9719.7; PLM2  Protein of unknown function AAB64943
15 YLR238w AAB67404 Phosphoprotein BD FHA FHA Ylr238w; Q06001;  L8083.1 Protein of unknown function AAB67404
16 YLR183c AAB67474 Phosphoprotein BD FHA FHA Ylr183c; Q06266; L9470.22  Protein of unknown function AAB67474
17 YLR016C CAA97538 Phosphoprotein BD FHA FHA YLR016c; Q06901; Q07930; L1591  Protein of unknown function CAA97538
18 RAD53 CAA97858 Phosphoprotein BD FHA FHA RAD53; MEC2; (SAD1); P2588; YPL153C; SPK1 Serine/threonine/tyrosine protein kinase with a checkpoint function in S and G2 CAA97858
19 MEK1 CAA99680 Phosphoprotein BD FHA FHA MEK1; MRE4; O6357; YOR351C  Serine/threonine protein kinase required for meiotic recombination CAA99680
20 YHR115C AAB68865 Phosphoprotein BD FHA FHA YHR115C; YHR5  Protein of unknown function AAB68865
21 DUN1 CAA98668 Phosphoprotein BD FHA FHA DUN1; D2370; YDL101C  Protein kinase required for induction of Rnr3p and DNA repair genes after DNA damage CAA98668
22 FHL1 AAB68074 Phosphoprotein BD FHA FHA FHL1; P8283.15A; YPR104C  Transcriptional activator of the forkhead/HNF3 family AAB68074
23 FKH1 CAA86147 Phosphoprotein BD FHA FHA FKH1; YIL131C  Homolog of Drosophila forkhead protein CAA86147
24 FKH2 CAA95942 Phosphoprotein BD FHA FHA FKH2; N2403; YNL2403; YNL068C  Homolog of Drosophila forkhead protein CAA95942
25 YNL116W CAA95996 Phosphoprotein BD FHA FHA YNL116w; N1925  Protein of unknown function CAA95996
26 HCM1 CAA42280 Phosphoprotein BD FHA FHA HCM1; YCR902; YCR065W  Dosage-dependent suppressor of cmd1 and member of the forkhead family of DNA-binding proteins CAA42280
               
# Sequence   Superfamily Group Family Specificity Description ACC#          
1 CLN1 CAA87822 Cyclin Cyclin CycA CLN1; PSC1; YM9646.13; YMR199W  G1/S-specific cyclin that interacts with Cdc28p protein kinase to control events at START CAA87822
2 CLN2 CAA97982 Cyclin Cyclin CycA CLN2; P0741; PSC2; YPL256C  G1/S-specific cyclin that interacts with Cdc28p protein kinase to control events at START CAA97982
3 CLB1 CAA97112 Cyclin Cyclin CycB CLB1; SCB1; G5967; YGR108W  G2/M-phase-specific cyclin CAA97112
4 CLB2 AAB68060 Cyclin Cyclin CycB CLB2; P9642.6; YPR119W  G2/M-phase-specific cyclin AAB68060
5 CLB3 CAA98729 Cyclin Cyclin CycB CLB3; D1539; YDL155W  2/M-phase-specific cyclin CAA98729
6 CLB4 AAB67425 Cyclin Cyclin CycB CLB4; L8167.3; YLR210W  G2/M-phase-specific cyclin AAB67425
7 CLB5 AAB68061 Cyclin Cyclin CycB CLB5; P9642.8; YPR120C  B-type cyclin appearing late in G1, involved in initiation of DNA synthesis AAB68061
8 CLB6 CAA97113 Cyclin Cyclin CycB CLB6; G5970; YGR109C  B-type cyclin appearing late in G1, involved in initiation of DNA synthesis CAA97113
9 CLN3 AAC04991 Cyclin Cyclin CycB CLN3; DAF1; WHI1; FUN10; YAL040C  G1/S-specific cyclin that interacts with Cdc28p protein kinase to control events at START AAC04991
10 YBR095C CAA85048 Cyclin Cyclin CycB YBR095C; YBR0822  Protein with similarity to Drosophila cyclin B CAA85048
11 CCL1 CAA89279 Cyclin Cyclin CycH CCL1; YP9367.05; YPR025C  Cyclin C component of RNA polymerase transcription initiation factor TFIIH; required for PolII transcription, for nucleotide excision repair, and for activity of Kin28p CAA89279
12 SSN8 CAA95887 Cyclin Cyclin CycK SSN8; SRB11; UME3; (NUT8); GIG3; N2805; YNL025C  Cyclin C homolog and component of RNA polymerase holoenzyme complex and Kornberg's mediator (SRB) subcomplex CAA95887
13 CTK2 CAA89296 Cyclin Cyclin CycK CTK2; J1390; YJL006C  C-terminal domain (CTD) kinase beta subunit, cyclin-related protein component that interacts with the cyclin-dependent protein kinase Ctk1p CAA89296
14 PCL1 CAA96206 Cyclin Cyclin PHO80 PCL1; HCS26; N0536; YNL289W  G1/S-specific cyclin that can interact with the Cdc28p-like kinase Pho85p CAA96206
15 PCL2 CAA98695 Cyclin Cyclin PHO80 PCL2; CLN4; ORFD; D2223; YDL127W  Cyclin, found partly in association with Pho85p CAA98695
16 PCL5 AAB68375 Cyclin Cyclin PHO80 PCL5; H8025.1; YHR071W  Cyclin; associates with Pho85p AAB68375
17 PCL6 AAB64595 Cyclin Cyclin PHO80 PCL6; YER059W  Cyclin; associates with Pho85p AAB64595
18 PCL7 CAA86172 Cyclin Cyclin PHO80 PCL7; YIL050W  Cyclin; associates with Pho85p CAA86172
19 PCL8 CAA97934 Cyclin Cyclin PHO80 PCL8; P1745; YPL219W  Cyclin that associates with Pho85p, involved in control of glycogen accumulation CAA97934
20 PCL9 CAA98753 Cyclin Cyclin PHO80 PCL9; D1408; YDL179W  Cyclin; associates with Pho85p CAA98753
21 PCL10 CAA96845 Cyclin Cyclin PHO80 PCL10; G2838; YGL134W  Cyclin, associates with Pho85p, involved in glycogen accumulation CAA96845
22 PHO80 CAA99000 Cyclin Cyclin PHO80 PHO80; TUP7; AGS3; VAC5; O2505; YOL001W  Cyclin that interacts with Pho85p protein kinase; regulates the phosphate pathway through phosphorylation of Pho4p CAA99000
23 CLG1 CAA96931 Cyclin Cyclin PHO80 CLG1; G1105; YGL215W  Cyclin-like protein, associates with Pho85p CAA96931