CLUSTAL W (1.83) multiple sequence alignment TESK2_Hsap_TESK MDRSKRNSI-AG-FPP--R----------------------------------------- TESK1_Hsap_TESK MAGERP-PL-RG-PGP-GP----------------------------------------- LIMK2_Hsap_LIMK MGSYLSVP----------------------------------------------AYFTSR LIMK1_Hsap_LIMK MRLTLLCCTWRE-ERMG--------E-EGSELPVCASCGQRI---YDGQYLQALNADWHA LIMK1_Dmel_LIMK MHHQQRLRA-NG-GRGGTGLGAGSGPVSGGHSPLCAHCRGQLLPHPEEPIVMALGQQWHC cdi_Dmel_TESK MSLNQHSG--PG-PPS--EIC--------------------------------------- LIMK2_Mmus_LIMK MGSYLSVP----------------------------------------------AYFTSR LIMK1_Mmus_LIMK MRLTLLCCTWRE-ERMG--------E-EGSELPVCASCGQRI---YDGQYLQALNADWHA TESK1_Mmus_TESK MAGERP-PL-RG-PGP-------------------------------------------- TESK2_Mmus_TESK MDRSKRNSI-AG-FPP--R----------------------------------------- DDB0229851_Ddis_LISK-DD1 MSKLFQDS---------------------------------------------------- DDB0229853_Ddis_LISK-DD1 MNINFSKD----------DI---------------------------------------- DDB0229854_Ddis_LISK-DD1 MAEADP------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 MNVGVKVR----------EI---------------------------------------- DDB0229865_Ddis_LISK-DD1 MKIKDF------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 MISMDSTPT-LNFETS-DNL---------------------------------------- DDB0229867_Ddis_LISK-DD1 MVGG-------------------------------------------------------- KinX_Ddis_LISK-DD1 MGSVDTS----------------------------------------------------- KinY_Ddis_LISK-DD1 MINGEQTMV-ED-ELP-D------------------------------------------ LIMK_Spur_LIMK MSCADIFF--RS-Q---------------------------------------------- Tesk_Spur_TESK MNIDEKLTA--K-Q---------------------------------------------- CC1G_09729_Ccin_LISK-DD1 MHSDA------------------------------------------------------- AqueK481_Aque_LIMK MGRMWH-----------------------------------------------------L AqueK482_Aque_TESK MVDSKFSA-----LPA--QLS--------------------------------------- AqueK483_Aque_TESK MNFLRRVGR-SS-RSP-SPLTRGSG--------------NN------------------- AqueK484_Aque_TESK MTDGVDDTL-Q------------------------------------------------- * TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK DLFRCSECQDSLTNWYYEKDGKLYCPKDYWGK-------------------FGEFCHGCS LIMK1_Hsap_LIMK DCFRCCDCSASLSHQYYEKDGQLFCKKDYWAR-------------------YGESCHGCS LIMK1_Dmel_LIMK DCFRCSVCEGHLHNWYFEREGLLYCREDYYGR-------------------FGDACQQCM cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK DPFRCSECQESLTNWYYEKDGKLYCHKDYWAK-------------------FGEFCHGCS LIMK1_Mmus_LIMK DCFRCCECSVSLSHQYYEKDGQLFCKKDYWAR-------------------YGESCHGCS TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 -----------------------------------S------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ECFRCTVCHVTLPECYYEEDGLSYCKDDFFKR-------------------LSHKCHQCS AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------SPTDDWSNTRSNTGNRSSSSSSGTANRKKEGKEERK AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK LLMT-GPFMVAG-EFKYHPECFACMSCKVIIEDGDAYALVQHATLYC------------- LIMK1_Hsap_LIMK EQITKGLVMVAG-ELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYC------------- LIMK1_Dmel_LIMK AVIT-GPVMVAG-EHKFHPECFCCTACGSFIGEGESYALVERSKLYC------------- cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK LLMT-GPAMVAG-EFKYHPECFACMSCKVIIEDGDAYALVQHATLYC------------- LIMK1_Mmus_LIMK EHITKGLVMVAG-ELKYHPECFICLACGNFIGDGDTYTLVEHSKLYC------------- TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ----------TG------------------------------------------------ DDB0229854_Ddis_LISK-DD1 -----------G------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ----------TG------------------------------------------SIGVIE DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ----------DG------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ----------QG------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK DYIT-GPTMAVGFSRMYHPECFHCTVCETTLGEKDIYCLLNTKDILC------------- AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK EHSTSGSNMIDGV--------------------DDNLQLTEAGCLVPDTPLSPSS----- AqueK484_Aque_TESK --------------------------------------LTEAGGLVPDMSLSP-S----- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ---------------------------------------------GKCHNE-VVLAPMFE LIMK1_Hsap_LIMK ---------------------------------------------GHCYYQ-TVVTPVIE LIMK1_Dmel_LIMK ---------------------------------------------GQCYGK-RSCQPADA cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ---------------------------------------------GKCHNE-VVLAPMFE LIMK1_Mmus_LIMK ---------------------------------------------GQCYYQ-TVVTPVIE TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 KGNNQNGFFVNFGSRKNWKRNNEVEVIQNTIDNSNGKQSTTPKPIAQQQQQ-QQPPPQQS DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ---------------------------------------------NDCSISDSCINGMIS AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK RLSTESVQEQLPYSVT-------------LISMPATT----------------------- LIMK1_Hsap_LIMK QILPDSPGSHLPHTVT-------------LVSIPASS----------------------- LIMK1_Dmel_LIMK KARITTAGKP-MHSIR-------------LVEIPKDA--T-------------------- cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK RLSTESVQDQLPYSVT-------------LISMPATT----------------------- LIMK1_Mmus_LIMK QILPDSPGSHLPHTVT-------------LVSIPASA----------------------- TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 QQQPPQPL-------KPIPATRP------VPTIPKVQSEDPGPRFGNFTLPTTNSSTKYS DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK --------SHDPS----------------------------------------------- Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK PVKTNSGR-TVYVSIQQIKVTLQRRVRFRLDGLPPAE----------------------- AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK --------------------------------EGRRGFSVS-VESA---------CSNYA LIMK1_Hsap_LIMK --------------------------------HGKRGLSVS-IDPP---HGPPGCGTEHS LIMK1_Dmel_LIMK --------------------------------PGLRVDGVA-LDD--------GC----- cdi_Dmel_TESK -----------------------------GLS--VDQVDSSAASPFIWPST-AGM----- LIMK2_Mmus_LIMK --------------------------------ECRRGFSVT-VESA---------SSNYA LIMK1_Mmus_LIMK --------------------------------HGKRGLSVS-IDPP---HGPPGCGTEHS TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------L----- DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------L----- DDB0229863_Ddis_LISK-DD1 TLPSRQFFEVSSSPGDENGTFKRSAAPPPPSSLSSNQNGSNLNKVQSPSRP-S-I----- DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------L----- DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------L----- KinX_Ddis_LISK-DD1 ------------------------------------------------------V----- KinY_Ddis_LISK-DD1 ------------------------------------------------------K----- LIMK_Spur_LIMK -------------------------------------------------TGS-------- Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK --------------------------------GEKKRLSIKDFTPP---QL-PNPNQKTS AqueK482_Aque_TESK ----------------------------------SDSDD--------------------- AqueK483_Aque_TESK --------------------------PVPPLSIKPHPLSS-SVSPP---NS-PGS----- AqueK484_Aque_TESK --------------------------PVPPISIEPHSLSS-SVSPP---DS-PGP----- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK TTVQVKEVN-----------------RMHISPNNRNA---------------IHPGDRIL LIMK1_Hsap_LIMK HTVRVQGVD-----------------PGCMSPDVKNS---------------IHVGDRIL LIMK1_Dmel_LIMK PTVRITDLFCNFFLWLTSMAEQCCGAPYRI-DVNLTN---------------LHIGDRIL cdi_Dmel_TESK CTT-------------------------------------ATTVTTSTNGDAT------- LIMK2_Mmus_LIMK TTVQVKEVN-----------------RMHISPNNRNA---------------IHPGDRIL LIMK1_Mmus_LIMK HTVRVQGVD-----------------PGCMSPDVKNS---------------IHVGDRIL TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 P----------------------------------------------------------- DDB0229854_Ddis_LISK-DD1 P----------------------------------------------------------- DDB0229863_Ddis_LISK-DD1 P----------------------------------------------------------- DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 P----------------------------------------------------------- DDB0229867_Ddis_LISK-DD1 P----------------------------------------------------------- KinX_Ddis_LISK-DD1 P----------------------------------------------------------- KinY_Ddis_LISK-DD1 P----------------------------------------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK YKKKVLKIE-----------------KLPRS-LIGTP---------------LKSGDIIM AqueK482_Aque_TESK ----------------------------------------------------S------- AqueK483_Aque_TESK PTVTISASE-----------------KLCKKPHPRSLDMRKLSIPTSVSLDCI------- AqueK484_Aque_TESK PTVTISASE-----------------KLCKKPHPQSLGMKKLSIPTSASLDCI------- TESK2_Hsap_TESK --------VERLEEFEGG------------------------------------------ TESK1_Hsap_TESK --------GEVPGEGPPG------------------------------------------ LIMK2_Hsap_LIMK EINGTPVRTLRVEE----VEDAISQTSQTLQLLIEHDPVSQR------------------ LIMK1_Hsap_LIMK EINGTPIRNVPLDE----IDLLIQETSRLLQLTLEHDPHDTL------------------ LIMK1_Dmel_LIMK EVNGTPVSDSSVEQ----IDKLIRSNEKMLQLTVEHDPVQVC------------------ cdi_Dmel_TESK --AEAP--VKHQPLHNGG------------------------------------------ LIMK2_Mmus_LIMK EINGTPVRTLRVEE----VEDAIKQTSQTLQLLIEHDPVPQR------------------ LIMK1_Mmus_LIMK EINGTPIRNVPLDE----IDLLIQETSRLLQLTLEHDPHDSL------------------ TESK1_Mmus_TESK --------GEAPGEG--------------------------------------------- TESK2_Mmus_TESK --------VERLEEFEGG------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 -----------------SFEPPTQQPTQPLQKSPRNVPIVPKRTNPSPPSPPLQSPQPTP DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ----------K------------------------------------------------- Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK EINEIPIINQNQEE----INNLMEVYDDCLYLMIERNSNQSH------------------ AqueK482_Aque_TESK --DYSP------PNSRK------------------------------------------- AqueK483_Aque_TESK --KH-------------------------------------------------------- AqueK484_Aque_TESK --NEYE--REKEEEYDSF------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 QQQPPPLKPIPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPPPLKPIPQPQQSQPTQ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK --------------G--------------------------------------------- TESK1_Hsap_TESK --------------P--------------------------------------------- LIMK2_Hsap_LIMK --------------LDQLRLEARL-----APHMQNAGHPHALST-----------LD--T LIMK1_Hsap_LIMK --------------GHGLG-----------------PETSPLSSP----------AY--T LIMK1_Dmel_LIMK --------------RSCSQAD--I-----QRAMSASTLILPLSTSASSVEVGRERLY--K cdi_Dmel_TESK --------------W--------------------------------------------- LIMK2_Mmus_LIMK --------------LDQLRLDARL-----PPHMQSTGHTLMLST-----------LD--T LIMK1_Mmus_LIMK --------------GHGPV-----------------SDPSPLSSP----------VH--T TESK1_Mmus_TESK --------------P--------------------------------------------- TESK2_Mmus_TESK --------------G--------------------------------------------- DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 PIKSQIQIPITNTNG--------------------------------------------- DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK --------------------------------------------V----------MH--A Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK --------------DKGSS-NHLVSQNSTSSELDVTSEIHSVSSP----------AHHKP AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK -------------NG--------------------------------------------- AqueK484_Aque_TESK -------------RV--------------------------------------------- TESK2_Hsap_TESK -GG---EG---------------------------------------------------- TESK1_Hsap_TESK -GG---TG---------------------------------------------------- LIMK2_Hsap_LIMK KENLEG----------------------TLRRRSLRRS-N-------------------- LIMK1_Hsap_LIMK PSGEAGS---------------------SARQKPVLRS-C-------------------- LIMK1_Dmel_LIMK TPGEQGT---------------------KAR--KLRQA-TN------------------- cdi_Dmel_TESK -IG---NG---------------------------------------------------- LIMK2_Mmus_LIMK KENQEG----------------------TLRRRSLRRS-N-------------------- LIMK1_Mmus_LIMK PSGQAAS---------------------SARQKPVLRS-C-------------------- TESK1_Mmus_TESK -GG---AG---------------------------------------------------- TESK2_Mmus_TESK -GG---DG---------------------------------------------------- DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 -NT---NG---------------------------------------------------- DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK SSCNWGE---------------------RR------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK PLGEAADSNTLHVNGSLPAVPENSQSSQTSSYKPKLRPSLSSSGLSNPDYDLDLTKSLNV AqueK482_Aque_TESK ------GG---------------------------------------------------- AqueK483_Aque_TESK -DY---DS---------------------------------------------------- AqueK484_Aque_TESK -DS---DS---------------------------------------------------- TESK2_Hsap_TESK --------N--VS-----------------------------------QVGR-VW-PSSY TESK1_Hsap_TESK --------G---------------------------------------GPGR-GR-PSSY LIMK2_Hsap_LIMK ---SISKSPGPSSP--K--------------------------EPLLFSRDI-SR-SESL LIMK1_Hsap_LIMK ---SIDRSPGAGSL--G--------------------------SPASQRKDL-GR-SESL LIMK1_Dmel_LIMK --ASTTIPPAAGAT--AMTQLKEKERCSSLSKLLDEQHQAQQHSAHPQLYDL-SR-TQSC cdi_Dmel_TESK -------LP--PAP--V---------------------------TRTISSDRLVT-GSSC LIMK2_Mmus_LIMK ---SISKSPGPSSP--K--------------------------EPLLLSRDI-SR-SESL LIMK1_Mmus_LIMK ---SIDTSPGTSSL--A--------------------------SPASQRKDL-GR-SESL TESK1_Mmus_TESK --------G---------------------------------------GPGR-GR-PSSY TESK2_Mmus_TESK --------N--TV-----------------------------------QVGR-VS-SSSY DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ----------------K--------------------------------STK-------- DDB0229854_Ddis_LISK-DD1 ----------------T------------------------------------------- DDB0229863_Ddis_LISK-DD1 -------H---SSLVEK--------------------------------SPR-NNESTAT DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ----------------D------------------------------------------- DDB0229867_Ddis_LISK-DD1 ----------------N------------------------------------------- KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ----------------M------------------------------------------- LIMK_Spur_LIMK -----NNYPVMCSP--T--------------------------------SPL-SR-TQSY Tesk_Spur_TESK ------------------------------------------------------R----- CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK PSNPVPVSHGTAAI--P--------------------------VPRLVRS---RR-AQSV AqueK482_Aque_TESK -------TP------------------------------------------R-PK-SSSF AqueK483_Aque_TESK --------P--AH-----------------------------------HVPR-PS-SPLL AqueK484_Aque_TESK --------P--SH-----------------------------------HVPR-PS-S-AL TESK2_Hsap_TESK RA--LISAFSRLTRLDDF---TCEKIGSGFFSEVFKVRHRASGQVM--AL-KMNTLSS-- TESK1_Hsap_TESK RA--LRSAVSSLARVDDFH--CAEKIGAGFFSEVYKVRHRQSGQVM--VL-KMNKLPS-- LIMK2_Hsap_LIMK RC--SSSYSQQIFRPCDLI--HGEVLGKGFFGQAIKVTHKATGKVM--VMKELI-RCD-- LIMK1_Hsap_LIMK RV--VC-RPHRIFRPSDLI--HGEVLGKGCFGQAIKVTHRETGEVM--VMKELI-RFD-- LIMK1_Dmel_LIMK RV--VQ-KPQRIFRATDLV--IGEKLGEGFFGKVFKVTHRQSGEVM--VLKELH-RAD-- cdi_Dmel_TESK RA--LRTAVSALYSVDDF---VKEKIGSGFFSEVYKVTHRTTGQVM--VL-KMNQLRA-- LIMK2_Mmus_LIMK RC--SSSYSQQIFRPCDLI--HGEVLGKGFFGQAIKVTHKATGKVM--VMKELI-RCD-- LIMK1_Mmus_LIMK RV--VC-RPHRIFRPSDLI--HGEVLGKGCFGQAIKVTHRETGEVM--VMKELI-RFD-- TESK1_Mmus_TESK RA--LRSAVSSLARVDDFD--CAEKIGAGFFSEVYKVRHRQSGQVM--VL-KMNKLPS-- TESK2_Mmus_TESK RA--IISAFSRLTSLDDF---TREKIGSGFFSEVFKVRHRASGQVM--AL-KMNTLSS-- DDB0229851_Ddis_LISK-DD1 ----NKRMSRI-VDYDEIKFDPLSIIGSGGFGKVYQGVLNGK-EIGI---KKITISDNDP DDB0229853_Ddis_LISK-DD1 EE--DENDFSS-LDYSDL-F-MDVEIGRGSFGQVQKASYFGT-DVAV---KQLSTLVS-- DDB0229854_Ddis_LISK-DD1 -----Q-AIWD-IPFESLE--FNEKIGKGSFGSVFRGCYLGL-DVAI---KKIEKAD--- DDB0229863_Ddis_LISK-DD1 TA--TTKDMWN-IDYKELKF-VGNEIGSGKYGSVSLGYWLGT-PVAI---KKLHENNEE- DDB0229865_Ddis_LISK-DD1 ----------N-IECDNLKIE-ENEFSKGSFAKVYKGSYYGN-PVCVKVIKKDTLIDKES DDB0229866_Ddis_LISK-DD1 -----GSNAFK-INIDDLE--FGQEIGKGAYGKIFKGEYFGT-PVAI---KEISLQPNDV DDB0229867_Ddis_LISK-DD1 ------SSLWN-IEYDDLV--FKDIIGKGNFGCVYRGNYLGV-EVAI---KQIPSF-DD- KinX_Ddis_LISK-DD1 ----SFDRAWS-IKYEDLD--FISEIGSGGFGKVFKGEYLGA-PVAI---KKIHILPDDP KinY_Ddis_LISK-DD1 -----SDESAD-IDIKDLK--VGESIGSGAYGIVYRGTLFNS-DVAI---KKIQNEKSE- LIMK_Spur_LIMK RV----SKNQRIFRPADLI--KGEVLGQGFFGKAVKVTHRYTGEVM--VIKELV-RYS-- Tesk_Spur_TESK ------------------------------EESKTKIRHKADGRVM--VAKIGKQKIW-- CC1G_09729_Ccin_LISK-DD1 --------FDV-IPYEDIKG-DWKKLGSGSFGNVYKGSYLGI-DVAI---KEVLPSN--- AqueK481_Aque_LIMK PVIDGRAGYTSCFRLHDLI--IGEVLGHGFYGNVIKVTHRYTEQVM--VMKEMR-NCT-- AqueK482_Aque_TESK IA--LKDAVYQLTCLNDF---TREKIGQGFFAEVFKVTHKNTGEVM--VL-KLNKSRN-- AqueK483_Aque_TESK SA--LREAVESVSNMEDFE--RIEKIGSGFFAEVYKVRHKLTDEIM--VL-KVNKGLT-- AqueK484_Aque_TESK RA--LREAVGSVSNMEDFE--RIEKIGSGFFADVYKVRRKLTNQIM--VL-KVNKGLT-- : TESK2_Hsap_TESK ----NRANMLKEVQLMNRL---SHPNILRFMGVCVH-------------Q-GQLHALTEY TESK1_Hsap_TESK ----NRGNTLREVQLMNRL---RHPNILRFMGVCVH-------------Q-GQLHALTEY LIMK2_Hsap_LIMK --EETQKTFLTEVKVMRSL---DHPNVLKFIGVLYK-------------DK-KLNLLTEY LIMK1_Hsap_LIMK --EETQRTFLKEVKVMRCL---EHPNVLKFIGVLYK-------------DK-RLNFITEY LIMK1_Dmel_LIMK --EEAQRNFIKEVAVLRLL---DHRHVLKFIGVLYK-------------DK-KLHMVTEY cdi_Dmel_TESK ----NRPNMLREVQLLNKL---SHANILSFMGVCVQ-------------E-GQLHALTEY LIMK2_Mmus_LIMK --EETQKTFLTEVKVMRSL---DHPNVLKFIGVLYK-------------DK-KLNLLTEY LIMK1_Mmus_LIMK --EETQRTFLKEVKVMRCL---EHPNVLKFIGVLYK-------------DK-RLNFITEY TESK1_Mmus_TESK ----NRSNTLREVQLMNRL---RHPNILRFMGVCVH-------------Q-GQLHALTEY TESK2_Mmus_TESK ----NRANLLKEMQLMNRL---SHPNILRFMGVCVH-------------Q-GQLHALTEY DDB0229851_Ddis_LISK-DD1 NRDILLKFLEREIYTLKML---SHPNVIKFYGIAEK-------------E-RSLFLLTEL DDB0229853_Ddis_LISK-DD1 IDPDYFKFMLREIKILKGM---RHPNIVQYIGACCH-------------E-GRYMIVTEY DDB0229854_Ddis_LISK-DD1 -DPEYLKYIDREVSMLQSL---RHPFIVNFSGICVH-------------S-SGLYIVTEF DDB0229863_Ddis_LISK-DD1 ----TEILVQRELQILKEI---RHPQIVQFLGVSRN-------------EKDEIHIITEF DDB0229865_Ddis_LISK-DD1 -----WVFLKREIGILKNLLNQGHKNIIRFIGIGEK-------------D-SLLFLVTEL DDB0229866_Ddis_LISK-DD1 KYKDLTKFIQREVAML-RF---SHPNLVQFIGVSER-------------G-SSLYIVTEF DDB0229867_Ddis_LISK-DD1 --PDYCKYTEREVKALRYI---RHPFVVHFFGACKH-------------E-SGFYLITEF KinX_Ddis_LISK-DD1 NRVDLEKFLNREIETIKLF---THPNVIQFVGISEN-------------N-GILFIVTEL KinY_Ddis_LISK-DD1 -KNEFIKYLKREVAVLKNI---QHPNIVQFIGVYYEPLASPSLVNRLLNS-SSTWIVTEY LIMK_Spur_LIMK --DSAQRDFLKEVKVLRSL---DHYHVLKFIGVLYR-------------DK-RLNLVTEF Tesk_Spur_TESK --RANQHKMIQELELLNKL---QHPNVVRYMGACVK-------------DG-HIHPVLEY CC1G_09729_Ccin_LISK-DD1 -DYDVAKYFEREWRLMKEC---RHPNICLFIGLSRAP----------PPD-NRIFIVSEF AqueK481_Aque_LIMK --EEAKKTFRKEVAVLKRL---HHPNLLKFIGILYQ-------------EDKLLTLITEF AqueK482_Aque_TESK ----NSKQMLAEIQLLNRL---SHSNILGFKGSCVH-------------E-GSLHALTEY AqueK483_Aque_TESK -----GTKTRQEVELLKRL---HHPNILHYIGSCIH-------------N-GQLHPLTEF AqueK484_Aque_TESK -----ATKTRQEVELLKRL---NHPNILHYIGSCIH-------------N-EQLHPLTEF * : * : : * : * TESK2_Hsap_TESK INSGNLEQLLDS-N----------------------------------LHLPWTVRVKLA TESK1_Hsap_TESK MNGGTLEQLLSS-P----------------------------------EPLSWPVRLHLA LIMK2_Hsap_LIMK IEGGTLKDFLRSM-----------------------------------DPFPWQQKVRFA LIMK1_Hsap_LIMK IKGGTLRGIIKSMD----------------------------------SQYPWSQRVSFA LIMK1_Dmel_LIMK VAGGCLKELIHDPA----------------------------------QVLPWPQRVRLA cdi_Dmel_TESK INGGSLEQLLANKE----------------------------------VVLSATQKIRLA LIMK2_Mmus_LIMK IEGGTLKDFLRSV-----------------------------------DPFPWQQKVRFA LIMK1_Mmus_LIMK IKGGTLRGIIKNMD----------------------------------SQYPWSQRVSFA TESK1_Mmus_TESK MNGGTLEQLLSS-P----------------------------------EPLSWPVRLHLA TESK2_Mmus_TESK INSGNLEQLLDS-D----------------------------------LYLPWTVRVKLA DDB0229851_Ddis_LISK-DD1 VSGGDLHWYIKNKS----------------------------------IDITWKLKVKIA DDB0229853_Ddis_LISK-DD1 IKGGDLHQFIKARG---------------------------------VSNISWTLRMKLA DDB0229854_Ddis_LISK-DD1 VSGGDVRQLLKK-T----------------------------------PPIGWDKRVSIA DDB0229863_Ddis_LISK-DD1 MDGGDLFDALIFGD----------------------------------IPLTWKEKLRIS DDB0229865_Ddis_LISK-DD1 INGGDLGNILLDHK----------------------------------FHIPWSLRVKIA DDB0229866_Ddis_LISK-DD1 VQGGDLAYYLFRNKFDDTPEQYIHRKVNVGSSSTPDLSDPTVHNGEKLVQLAWPLRIKIA DDB0229867_Ddis_LISK-DD1 IEGLDLRRYLKSV----------------------------------PKPPKWLSRVNIA KinX_Ddis_LISK-DD1 IEGGDLQYYLKNQS----------------------------------IDLPWFLRANIA KinY_Ddis_LISK-DD1 IGGGNLHERIKDTK----------------------------------KDFPIELRIKLS LIMK_Spur_LIMK VGGGTLENIISDLD----------------------------------KPFPWLQRINAA Tesk_Spur_TESK VSGGCLTDILADES----------------------------------LALSWRQKGDLA CC1G_09729_Ccin_LISK-DD1 IEGGNVRLYIHDKN----------------------------------KPFPWRLRMSFA AqueK481_Aque_LIMK IGGGTLRKRIKKKD----------------------------------VPFPWKLRIQIA AqueK482_Aque_TESK INGGTLEELLSS-D----------------------------------PHLSWSKRIKIA AqueK483_Aque_TESK VNGGTLKSLIQDVE---------------------------------KNPFPPEQRIQLS AqueK484_Aque_TESK VNGGTLKSLIQDVE---------------------------------KNPFPREQRIQLS : . : : : : TESK2_Hsap_TESK YDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN-GYSAVVADFGLAEKIPDVS-------- TESK1_Hsap_TESK LDIARGLRYLHSKGVFHRDLTSKNCLVRREDR-GFTAVVGDFGLAEKIPVYRE------- LIMK2_Hsap_LIMK KGIASGMAYLHSMCIIHRDLNSHNCLIKLDK----TVVVADFGLSRLIVEERKRA----- LIMK1_Hsap_LIMK KDIASGMAYLHSMNIIHRDLNSHNCLVRENK----NVVVADFGLARLMVDEKTQP----- LIMK1_Dmel_LIMK RDIACGMSYLHSMNIIHRDLNSMNCLVREDR----SVIVADFGLARSVDAPRLPSGNM-T cdi_Dmel_TESK LGIARGMSYVHDAGIFHRDLTSKNVLIRNLANDQYEAVVGDFGLAAKIPVK--------- LIMK2_Mmus_LIMK KGISSGMAYLHSMCIIHRDLNSHNCLIKLDK----TVVVADFGLSRLIVEERKRP----- LIMK1_Mmus_LIMK KDIASGMAYLHSMNIIHRDLNSHNCLVRENR----NVVVADFGLARLMIDEKNQS----- TESK1_Mmus_TESK LDIAQGLRYLHAKGVFHRDLTSKNCLVRREDR-GFTAVVGDFGLAEKIPVYRE------- TESK2_Mmus_TESK YDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN-GYSAVVADFGLAEKIPDAS-------- DDB0229851_Ddis_LISK-DD1 RDIAASMAYLHENGVIHRDLKSTNLLVAEN----WVIKVCDMGLARKMDK---------- DDB0229853_Ddis_LISK-DD1 LDIASAFSYLHSKKVIFRDLKAKNILVDEIGDGLYRAKVIDFGFARIFDG---------- DDB0229854_Ddis_LISK-DD1 VDLAKAMVFLHAKKIIHRDLKSKNILLDEFQ----RIRLCDFGFARMSEQ---------- DDB0229863_Ddis_LISK-DD1 LDIAQSCRFLHARGILHRDLKSQNILLSTN----RRAKLCDLGLARMFEE---------- DDB0229865_Ddis_LISK-DD1 KDIAEGMEYLHSKQIMHRDLKSNNLLLGRN----WTIKICDFGFAKEITI---------- DDB0229866_Ddis_LISK-DD1 YDVACAMAYLHSRNVIHRDLKSTNLLVGDNW----RIKVCDMGFARTAQVGGG------- DDB0229867_Ddis_LISK-DD1 LGVAKTFLFLHSKNLLHRDLKSKNILLDISR---NQIKLCDFGFARVGSQYSNGSDSSSS KinX_Ddis_LISK-DD1 LDVSLAMSYLHSKSIVHRDLKSTNLLVDKN----WKIKVCDFGFARIVEE---------- KinY_Ddis_LISK-DD1 LDIALAMAYLHSRDIIFRDLKSKNILIDDSSS-PIRGKVCDFGFARILNKK--------- LIMK_Spur_LIMK RDIASGMSYLHSMGIIHRDLNSNNCLVRDDG----SVVVADFGLARVFIDENDSRC---- Tesk_Spur_TESK TDIARGMTYLHSQNVCHRDLTSANCLVRQKPNNVLEAILTDFGLARVLGCMPDPP----- CC1G_09729_Ccin_LISK-DD1 TDVARALAYLHARKCIHRDLKGENLLVTSN----GRIKVTDFGFARIAARN--------- AqueK481_Aque_LIMK LDISAGMN----------------------S----RAVVADFGLARVFYPLDFSN----- AqueK482_Aque_TESK HDIANGMAYLHNRGVFHRDLTSKNCLIQKSDDGSLNCVVADFGLAAKIV----------- AqueK483_Aque_TESK LDMAMGMEYLHNNGMLHRDFNSHNCLLRKEGD-RYTAVVADFGLATKNPNLIK------- AqueK484_Aque_TESK LDMALGMEYLHENGMLHRDFNSNNCLLRKEGD-RYTAVVADFGLAAKNPNLMK------- .:: : *:*:: TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK --------------------------------PMEKATT-----------------KKRT LIMK1_Hsap_LIMK --------------------------------------E-----------------GLRS LIMK1_Dmel_LIMK P--------GG-Y-----------GSGANSDAPMSPSG------------------TLRR cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK --------------------------------PVEKATT-----------------KKRT LIMK1_Mmus_LIMK --------------------------------------E-----------------DLRS TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 EDESDSECVNGAAGGGGDDVYKNNGNGKPA------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK --------------------------------PNSF-GP-----------------GRDK Tesk_Spur_TESK --------------------------------PNSPRTPESPEPDIIDAPNGGPMLPRIP CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ----------------------------------------------------------DK AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ----MGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTE TESK1_Hsap_TESK ---GARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTE LIMK2_Hsap_LIMK LRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTL LIMK1_Hsap_LIMK LKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTM LIMK1_Dmel_LIMK SKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKLDVFSFGIMLCEIIGRVEADPDFMPRNS cdi_Dmel_TESK ----SRKSRLETVGSPYWVSPECLKGQWYDQTSDVFSFGIIQCEIIARIEADPDMMPRTA LIMK2_Mmus_LIMK LRKSDRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTL LIMK1_Mmus_LIMK LKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTM TESK1_Mmus_TESK ---GTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTE TESK2_Mmus_TESK ----IGREKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTE DDB0229851_Ddis_LISK-DD1 ----SEKSKMTICGTDDWMAPEVLIGEEYDASCDVFSFGMVLIELITRENLTPR--IRNE DDB0229853_Ddis_LISK-DD1 ----KDTNNLTICGSENTMSPEVIVGSSYNDSCDVYSYGVLLLELICGSRVVKTQLKRTP DDB0229854_Ddis_LISK-DD1 ---TKKSRHMTMCGTEGWVAPEILLGMSYDTSCDVFSYGVVLAELITGRKPGVDLWVRSP DDB0229863_Ddis_LISK-DD1 ----RINKRYTCVGTEIWMAPEVCLDQSYSTAVDVFSFGIVLVEIITEKIPDE--RFPQH DDB0229865_Ddis_LISK-DD1 ----QNPLSMTICGTDEFMSPEVILGIQYSYSADIYSFGMVLLELITRSKLDER--LPQN DDB0229866_Ddis_LISK-DD1 ---SRAKRTMTICGTTNCMAPEVVLGQDYNEACDVFSYGIVLSEIITRMDTTNNLRPSSL DDB0229867_Ddis_LISK-DD1 ---NYRLRRMSICGTPSFMPPEILLQQKYDWSVDVFSFGILCTELITLKRPGKDYWVRSQ KinX_Ddis_LISK-DD1 ----DNNKSMTICGTDNWMSPEMITGLDYDERSDIFSFGIVLLEIISRVKPAP--YMRDA KinY_Ddis_LISK-DD1 ---QQGNRHLSICGTDSIMAPELILGMEYDESVDIFSFGVVLLEMILRKKVSK-VLERGP LIMK_Spur_LIMK HQPAGRKKRYTMVGTAFWMAPEMLKGKDYNERVDVFSFGIVMCELIGRVSACPDDLPRSG Tesk_Spur_TESK SACMDVPRKMSVVGTAFWMAPEVLRGEEYTRQVDVFSFGIVVCEIVARITANPDDLPRTG CC1G_09729_Ccin_LISK-DD1 ---EEELRRLTFCGTDSYMSPEILLGDEFDLPTDVFSLGIIFCEIAARRLADDRHFKRHP AqueK481_Aque_LIMK SKKRNNRSRMTVVGSPYWMAPEMLKGQDYDETVDIFSFGIVLCEIISRVKSDPDELPRLN AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ----KLRRNQSMVGTPYWMAPEVLHGKEYNEKADTYSYGIVLCEIVSRKDADPDEIPR-- AqueK484_Aque_TESK ----DLRCNQSVVGTPFWMAPEVLHGKRYDKKADTYSYGIVLCEIVSRKDADPDEIPRND TESK2_Hsap_TESK --NFGLDY--DAFQH---MV-GDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTL------- TESK1_Hsap_TESK --DFGLDV--PAFRT---LVGDDCPLPFLLLAIHCCNLEPSTRAPFTEITQHL------- LIMK2_Hsap_LIMK --DFGLNV--KLFWEK--FVPTDCPPAFFPLAAICCRLEPESRAPPGAAGEGPGCADDEG LIMK1_Hsap_LIMK --DFGLNV--RGFLDR--YCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWL------- LIMK1_Dmel_LIMK --DFSLNQ--QEFREK---FCAQCPEPFVKVAFVCCDLNPDMRPCFETLHVWL------- cdi_Dmel_TESK --SFGLDY--LAFVE---LCPMDTPPVFLRLAFYCCLYDAKSRPTFHDATKKL------- LIMK2_Mmus_LIMK --DFGLNV--KLFWEK--FVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSF------- LIMK1_Mmus_LIMK --DFGLNV--RGFLDR--YCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWL------- TESK1_Mmus_TESK --DFGLDV--PAFRT---LVGNDCPLPFLLLAIHCCSMEPSTRAPFTEITQHL------- TESK2_Mmus_TESK --NFGLDY--DAFQN---MV-GDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTL------- DDB0229851_Ddis_LISK-DD1 --DLGVDQ--KFFLS---KVPADCPKELLRLVSECCKVAPSGRPSASNILGLL------- DDB0229853_Ddis_LISK-DD1 MNAFDMNL--EKAEH---LAPESCPRAFMDLAKWCCSYNPKDRPTFKIVVEGL------- DDB0229854_Ddis_LISK-DD1 ETCFDINP--EELKQ---KSIPGCPSELISVCVECCLYEPLTRPKFDEILSQL------- DDB0229863_Ddis_LISK-DD1 --RFQFDA--PAFLK---KVPKECPPDFSKLCVDCTKYNPKERPSFIKVLDTI------- DDB0229865_Ddis_LISK-DD1 --NFDIDY--EELQN---KIPSECPREFLELSMKCCNYDPNDRPSFTDIVQTL------- DDB0229866_Ddis_LISK-DD1 --KYGLDV--DVLLPL---VPKDCPPPFLKLVLDCTEYDPDNRPTFKEITERL------- DDB0229867_Ddis_LISK-DD1 --NNGFDINIEELNVN-IPSPNDCPIQFYDLALKCCSYKHTNRPMFSTIVTIL------- KinX_Ddis_LISK-DD1 --SFGLAE--DIVRNQ--LIPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTL------- KinY_Ddis_LISK-DD1 QSAFEIDQ--DSARQ---LIPDDIPVLYSDLALDCIKYQPEERPNFSHIIHVL------- LIMK_Spur_LIMK --DFGLDE--VPFMAQ---CCDTCPKTFHQIMLMCVRMDSDERPSFDELDQRL------- Tesk_Spur_TESK --KFGLDL--QLFKEK---CP-GIPEPFLQIAEDCCSMDPRDRPVFAELVRRF------- CC1G_09729_Ccin_LISK-DD1 -PTFGIDP--EEVRK---LATPGCPEDFLKLCLDCLNTEPARRPGTREILDRL------- AqueK481_Aque_LIMK --SFGLDE--LKFRE---M-RGDCPLLFYNLAVQCTSLNPEERPLFLDIRKGL------- AqueK482_Aque_TESK --------------------------------------DPDGRPTFDEIVQML------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --NFSLNE--AAFRELPEVIGSPCPPAFIDLACNCSKFVPDERPGFPIIPHPP------- TESK2_Hsap_TESK --------------EEILSRLQ-------EE-EQ----ERDR----------------K- TESK1_Hsap_TESK --------------EWILEQLP-------EP-AP----LTRT------------------ LIMK2_Hsap_LIMK PVRRQGKVTIKYDPKELRKHLNLEEWILEQLT-RLYDCQEEEISE--------------- LIMK1_Hsap_LIMK --------------ETLRMHLA-------GH-LPL----GPQLEQ--------------- LIMK1_Dmel_LIMK --------------QRLADDLA-------ADRVPP----ERLLHEIETFQEWYASSEDA- cdi_Dmel_TESK --------------TLLLEKYE-------HE-SS----AGAS----------------P- LIMK2_Mmus_LIMK --------------EALSLFLG-------ELAIPL----PAELED--------------- LIMK1_Mmus_LIMK --------------ETLRMHLS-------GH-LPL----GPQLEQ--------------- TESK1_Mmus_TESK --------------EQILEQQP-------EA-TP----LAKP------------------ TESK2_Mmus_TESK --------------KEIMSRLP-------EE-EL----ERDR----------------K- DDB0229851_Ddis_LISK-DD1 --------------EYILESEL-------IV-NSG---G-D-----------------Y- DDB0229853_Ddis_LISK-DD1 --------------KVLTNQQL-------KD-LPV---K-G------------------- DDB0229854_Ddis_LISK-DD1 --------------KVCQNNLK-------VA-TAA---A-AA------------------ DDB0229863_Ddis_LISK-DD1 --------------QNIYDSLP-------DD-D--------------------------- DDB0229865_Ddis_LISK-DD1 --------------DQLAIKLV-------KE-TPD---G-PY----------------P- DDB0229866_Ddis_LISK-DD1 --------------KSLTKKLS-------TP-HIL---P--------------------- DDB0229867_Ddis_LISK-DD1 --------------ESIKLQLE-------LF-ENQ---Q--------------------- KinX_Ddis_LISK-DD1 --------------KQIKTTLD-------SN-IVY---P--------------------- KinY_Ddis_LISK-DD1 --------------KQLTSLFP-------VV-HTF---D--N------------------ LIMK_Spur_LIMK --------------SSFSLHFE-------RL-SPR----AKDLES--------------- Tesk_Spur_TESK --------------EIIRGTLD-------TE-TSD----TTCYD---------------- CC1G_09729_Ccin_LISK-DD1 --------------RLIEAEVL-------AR-PAE---DGDV----------------N- AqueK481_Aque_LIMK --------------SHYINLIE-------SN-SPL----PDNLYD--------------- AqueK482_Aque_TESK --------------DPLVSAYQ-------SN-STP---PPAP----------------P- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --------------A-IMTNLR-------EN-YL----VLLQ----------------SL TESK2_Hsap_TESK -LQP-----TA------------------------------------------------- TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK -LSPTSQRSLNN--LDELVKSAVDSE------------IS-------------------- cdi_Dmel_TESK -LSSLE---LINCSP---------GGSDSENVTLTPRASV--PTVATICTAPAGTLTPRH LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK -LQP-----TA------------------------------------------------- DDB0229851_Ddis_LISK-DD1 -EPPLR--SFKP--P---------EL------------HL-------------------- DDB0229853_Ddis_LISK-DD1 ---KSK--PYID------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ---AAA--AAAAAAA---------VV------------ST--PT---------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 -STPIV---VSN--P---------HF------------DDQSI----------------- DDB0229866_Ddis_LISK-DD1 ---PLR--VLAQ--S---------PL------------TS--P----------------- DDB0229867_Ddis_LISK-DD1 ---QQQ--QLQQ-QQ---------QL------------QQ--Q----------------- KinX_Ddis_LISK-DD1 ---EIR--DFEQ------------------------------------------------ KinY_Ddis_LISK-DD1 ---PL----------------------------------S--P----------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ----V---NL-----------------------------T-------------------- CC1G_09729_Ccin_LISK-DD1 -VGSVR--FI----S---------GA------------RR--P----------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -IAP-----LSN--P---------SS----------------P----------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK EVDP-----V-------------------------------------------------- TESK2_Hsap_TESK -----------------RGLLEKAPGV---------KRL-S-S------LD--------- TESK1_Hsap_TESK ------------------------ALT---------HNQ-G-S------VA--------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK -------------------PVEK-------------EKE-N-MVIKPQDI---------- cdi_Dmel_TESK LQEVDEDGFRFPSKKSASAALPGTPNGS--------AGS-S-G------FD--------- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -------------------PLTKAPLT---------YNQ-G-S------VP--------- TESK2_Mmus_TESK -----------------KGPLEKVPGG---------KRL-S-S------LD--------- DDB0229851_Ddis_LISK-DD1 -------------------------------------------P-----LNE---KNN-- DDB0229853_Ddis_LISK-DD1 ------------------------------------PDE-D-SF-----IDPND------ DDB0229854_Ddis_LISK-DD1 -I---------------QTPII--------------QTP-NIS------FSPNNSNNNNN DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ---------------------------NDWCMLSLIPDDCL-EN-----LNEFA-EIE-- DDB0229866_Ddis_LISK-DD1 -I---------------QSPISTKNQFN--------PNL-F-KS-----IVHNN-HNH-- DDB0229867_Ddis_LISK-DD1 -Q---------------QQQQQQQ-QQQ--------QQ--Q-LQ-----LQQQQ-SSE-- KinX_Ddis_LISK-DD1 ----------------------------------------Q-QK-----ISTTN---G-- KinY_Ddis_LISK-DD1 -T---------------SSPIT--------------PRK-N-S------LN--------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK -------------------D-----------------------------II--------- CC1G_09729_Ccin_LISK-DD1 -G---------------AAPRI--PSFG-------------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -SKVELPAELCPSPQS--------PS---------------------------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -----------------------LPFL---------YAE-G-L------LT--------- TESK2_Hsap_TESK --------DK--------------------I-----P----------------------- TESK1_Hsap_TESK --------RG--------------------G-----P----------------------- LIMK2_Hsap_LIMK -----------------------------------------L------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------PKSPHLGKDFSPSGERLRDSM--- cdi_Dmel_TESK --------DH--------------------I-----L----------K-SRVRRATQKLE LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --------RG--------------------G-----P----------------------- TESK2_Mmus_TESK --------DK--------------------I-----P----------------------- DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 NNNNISNISPDITTGIQQINLSSSGGSNNSS-----PSTPPQGSQLVSLAQSRRNTM--- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 --------SP--------------------F-----TKS------------MRMNSF--- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK --------RT--------------------NDSDDDDDDCSFGFQFQTDLDDKRRSG--- CC1G_09729_Ccin_LISK-DD1 --------MG--------------------V-----GKD------------IRGGSG--- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK AEILLHRRSLSENIIHFP------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ---SLHRKSMELNLVDGQLSTTPPPTSPIQSRPHKPSDSIWKIAAKPKHVGYQTLKRKQG DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ---DFN------------LSNIVSSTS--------------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------MSSA-------------------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 PCYAALTSHITKMIERATSDYYYDTSYIQDFLLAYRCFAPPQQIFELLLSRYIANSPDNF DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 TNDINGWKKVQRVIQLRVIIFFKRWIDYYPQDFLEEAMEDNLNEFDKISAQQNSSTALLL DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ---------------------------------------------HKS------------ TESK1_Hsap_TESK ---------------------------------------------SA------------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK --------------------------------------------MHTS------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ---------------------------------------------SA------------- TESK2_Mmus_TESK ---------------------------------------------HKS------------ DDB0229851_Ddis_LISK-DD1 ----------------------------------------NNKNNNNNN---N------- DDB0229853_Ddis_LISK-DD1 ------------------------------------------DSNNNNN---S------- DDB0229854_Ddis_LISK-DD1 GTTISNNELLIDPKLMTELQKKRSELELLIQINSPSDFINNNNNNNN-N-PVN------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ----------------------------------------NNINNNNNN----------- DDB0229866_Ddis_LISK-DD1 ----------------------------------------SSSSNNSSG---Y------- DDB0229867_Ddis_LISK-DD1 ----------------------------------------SSSSSSSQP---L------- KinX_Ddis_LISK-DD1 ----------------------------------------NNKQNGGAP---K------- KinY_Ddis_LISK-DD1 --------------------------------------VQNNLKSQNLNFTLL------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ----------------------------------------------SSA---SSDESDEE AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 -----NNNNNN------------NNN------NNNNNNNNNNNNNNNNNNNNNNL---GN DDB0229853_Ddis_LISK-DD1 -----ENNNNN------------NDN------SNENNE-NNNENNNNSNENNN------- DDB0229854_Ddis_LISK-DD1 -----NINNIN------------NNNSVNSSSSNNNN-NNN------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------NNNNN------------NKN------NINNNNNNN-NNNNNNNNNN-------- DDB0229866_Ddis_LISK-DD1 -----NNNSNHNINITVNSININSSN------I--NNN-NNNNNINNNNNNNNNI----- DDB0229867_Ddis_LISK-DD1 -----VNNNNN------------NSN------CNNNNF-NNSSNNNNSIANNDSISNVST KinX_Ddis_LISK-DD1 -----INNLPL------------QYS------NNNNNIYDDDDDDDDDDDDND------- KinY_Ddis_LISK-DD1 -----NLNQIN------------NQD------LNENN-NNNI------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 LMEAVSRLTIT------------KAG------LEER-SAWST------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK --------PCPR-------RTI-------------------------------------- TESK1_Hsap_TESK --------TLPR-------PDP-------------------------------------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK --------RARRRQRFLGAQEE-------------------------------------- cdi_Dmel_TESK --------PSDKA------RCH-------------------------------------- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --------TLPR-------PDP-------------------------------------- TESK2_Mmus_TESK --------PRPR-------RTI-------------------------------------- DDB0229851_Ddis_LISK-DD1 SGNIYDDFSFPR-------PYQPDDSAVDNINNN---------GNDDSHFSFPRP----- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ----------------------------------------SFSGRQ---EELMSPISM-- DDB0229867_Ddis_LISK-DD1 -----TTTSIPT-------TTTTTTTT-----TTTTNNITAINGTS---NKYLQPLSKHQ KinX_Ddis_LISK-DD1 --------SFPR-------PYSDNSNSNVTLESNSNYNSSTINGQE---QQEQQEQQQQQ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK --------RTRLREVLCGCSKG-------------------------------------- CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 -----------------------------------YQP---------------------- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 -----------GDESDLDSDDEDDSYTSSA----------SSSRCN-------------- DDB0229867_Ddis_LISK-DD1 QQQQRNQNSSIIDNNSLIGSSNTESMITSFSISTFKERKKQSLNKLIRANTINILIGQQQ KinX_Ddis_LISK-DD1 QVKEERDEGEIEQDDD-----NIEV--YDSDYQKKLEEHQ-------------------- KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ---------------------------GQSNINGGVNNNNSNDESHFSFPRP--YQPGQ- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 -------------------------SRNGKIINGGKQMGYI-IKHHYSSDLE--SSPNG- DDB0229867_Ddis_LISK-DD1 QQQQQQQQQQQQQQDNQSSSQNQLIEREGVIKL------------------DTTKYPNGW KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 -----------------SNING---CVNNNNNNSNNNNDSHFSFPRPH------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 -------------------------NNNSNNNNN-------------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 -----------------NNIN---NNNNNNNNNN-------------------------- DDB0229867_Ddis_LISK-DD1 KEFGIDNSTNKIWIIYQSNIIKIGS---NNNNNLIEMTCGTIIKLKKHSITLSIVDSNLI KinX_Ddis_LISK-DD1 -----------------KEL---------------------------------------- KinY_Ddis_LISK-DD1 -------------------------SNNINNINN-------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 -------------------------SSSVQPLLD-------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 --------------------------------------------------QTSVVILNDR DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 SGANIINVKSYLKDYPYVNKPIKVNQQQQQQQQIITNNYELNLIIKLQSRIR-------- KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK -----W------------------------------------------------------ TESK1_Hsap_TESK -----R------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK -----R------------------------------------------------------ cdi_Dmel_TESK -----Q------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -----R------------------------------------------------------ TESK2_Mmus_TESK -----W------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 GEEEP---------------------------------------------LVVSQKDQLE DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ----GWLVRRRYKIFLSNWKLNNSNTSQSNKNQWIRLFNQLISSELEYKKQ-------LD KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK -----W------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 QVIKSYLLPIQSKFRINKPLLNYKEIGSIFSNIESLSEIHNELLKIVNQISKSPFFIMNF KinX_Ddis_LISK-DD1 -LE--------------------------------------------------------- KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK --------------------------------------LSRSQSDIFSRKPPRTVS---- TESK1_Hsap_TESK --------------------------------------LSRSRSDLFLPPSPE------- LIMK2_Hsap_LIMK ------------------------------------------------EID--------- LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ---------------------------------------R------NLTPDTE------- cdi_Dmel_TESK --------------------------------------MQRQRSSTHSPTPPRQLSSVQL LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --------------------------------------LSRSRSDLFLPPSPE------- TESK2_Mmus_TESK --------------------------------------LSRSQSDIFSHKPPRTVS---- DDB0229851_Ddis_LISK-DD1 -HDLEGGDDNEEDEMKQLKSQLNYSKFSFPRPYQSSKIISFNETELLSFPRPW------- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 EN---------------------------------------------------------- KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK --------------------------------------MT------NAEVDEQ------- CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ----------------------------------------RAEYDRLQSPEMMAQ----- TESK2_Hsap_TESK -----------------------VLDPYYRPRDGAA-RTPKVNPFSARQ---D------- TESK1_Hsap_TESK -----------------------------SPPNWGD-NLTRVNPFSLRE---D------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ----------------------------SKERALKKA-LKKCRPFGERGYLVD------- cdi_Dmel_TESK PATSIPDPPPLPKPVPAVLTLRKVGDPQYKPTSEKDHNGSKPNPFEALA---Q------- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -----------------------------SPPSWGD-NLTRVNPFSLRE---D------- TESK2_Mmus_TESK -----------------------VLDPYYQPRDGAT-HTPKVNPFSARQ---D------- DDB0229851_Ddis_LISK-DD1 -----------------------------NPESEEN-NNNKNNNNNEKS----------- DDB0229853_Ddis_LISK-DD1 ----------------------------------------KKNKNGSGG----------- DDB0229854_Ddis_LISK-DD1 ---------------------------------NNN-NNNNNNNNNN------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 --------------------------------------------NNCK------------ DDB0229866_Ddis_LISK-DD1 ---------------------------------NNN-NNNNNNNNNSGN----------- DDB0229867_Ddis_LISK-DD1 ---------------------------------EKD-DRSNQNNTSATT----------- KinX_Ddis_LISK-DD1 ----------------------------------------RQNQNQ-EG----------- KinY_Ddis_LISK-DD1 ---------------------------------NNN-NLNDCNSNLSS------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ----------------------------DCEKSFVDV-L-KEYAYAARQYFR-------- CC1G_09729_Ccin_LISK-DD1 ---------------------------------NQ------HTPNGS------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK --------------------------------------------SSLLS---S------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -----------------------------DRKTRAD-HLLRLLPNKGKN---YFQKFCIC TESK2_Hsap_TESK ------------LMG--GK-IK----------------FFD---LPS------------- TESK1_Hsap_TESK ------------LRG--GK-IK----------------LLD---TPS------------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------LRA--GAELQ----------------LED---VRD------------- cdi_Dmel_TESK ------------LRG--VK--K----------------ILD---ANP------------- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------LRG--GK-IK----------------LLD---TPC------------- TESK2_Mmus_TESK ------------LKG--GK-VK----------------FFD---LPS------------- DDB0229851_Ddis_LISK-DD1 L---------------------------LEDPKYSFPRPYN---PDSDSNLSFKS----- DDB0229853_Ddis_LISK-DD1 D-----------ISG--SS-VI----------------IKT---DEE------------- DDB0229854_Ddis_LISK-DD1 -GLNI-INIAAANQS--K--MMLQNGNNRYSVLVTSNGI--------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 NGICI-NSLSLGVSS--S------------------------------------------ DDB0229867_Ddis_LISK-DD1 D-----------IFG--DSSIQ----------------FTNISINT-------------- KinX_Ddis_LISK-DD1 S-----------TDE--NE-VY--EQEEEEEEEDEEEQVIS---TPAKKRISFGQDTFHT KinY_Ddis_LISK-DD1 -STSTIYND-----SQQT--IID------------------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------VVT--GFIVC----------------LLP---MLS------------- CC1G_09729_Ccin_LISK-DD1 ------------TYS--TS-V--------------------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------LLG--GS-VE----------------RDG---IIR------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK I-----------GKS--GQ-IE----------------LLE---KIG------------- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 YEAYRTDDEDDDDDEEDEEEGDEYDHGYDDFDEDDEDDEEYDEDEDDEDERQIQYYQQQL KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 QYQQQLQKQQEQEYQRQQQLQLQREEEEYQRQLQQQQQQQQQQQQQQQQHQQQYDDDDDD KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK -----KSVI--S------------------------------------------------ TESK1_Hsap_TESK -----KPVL--P------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK -----LN--TYS------------------------------------------------ cdi_Dmel_TESK -----KTYA--A------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -----KPATPLP------------------------------------------------ TESK2_Mmus_TESK -----KSVI--S------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ---------------TAKV----------------------------------------- DDB0229853_Ddis_LISK-DD1 -----ESFN--S------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ----KDSSN--QINSITQFIVKNISQIKNQYGIYAFNFKYSTNIYNWCRLNPDFSIFCDT KinX_Ddis_LISK-DD1 DDEEEEEYD--D------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK -----LW--MYC------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -----ERKI--S------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -----FDLTLLP------------------------------------------------ TESK2_Hsap_TESK -------------------------------LV---FD-------L---D---------- TESK1_Hsap_TESK -------------------------------LV---P------------P---------- LIMK2_Hsap_LIMK ----------------------------------------------VDE----------- LIMK1_Hsap_LIMK ----------------------------------------------LDR----------- LIMK1_Dmel_LIMK -------------------------------------D--------VDSS---------- cdi_Dmel_TESK -------------------------------GV---GD-------L---F---------- LIMK2_Mmus_LIMK ----------------------------------------------LDH----------- LIMK1_Mmus_LIMK ----------------------------------------------LER----------- TESK1_Mmus_TESK -------------------------------LV---P------------P---------- TESK2_Mmus_TESK -------------------------------LV---FD-------L---D---------- DDB0229851_Ddis_LISK-DD1 ------------------------------------------------IT---------- DDB0229853_Ddis_LISK-DD1 -------------------------------VV---YK-------EHAVA---------- DDB0229854_Ddis_LISK-DD1 ------------------------------------GN-------G---E---------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 -------PIQ---------------------IG---LS-------S---K---------- DDB0229867_Ddis_LISK-DD1 IRSQLNQQFPDQENDLASLLSLPINKIQKYLLV---FE-------KL--A---------- KinX_Ddis_LISK-DD1 -------------------------------VI----RHDTDSEEESKDK---------- KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ----------------------------------------------Y------------- Tesk_Spur_TESK -------------------------------------D--------LNNV---------- CC1G_09729_Ccin_LISK-DD1 --------------------------------IRQAAH-------S---NTPSAPALSSI AqueK481_Aque_LIMK ----------------------------------------------LL------------ AqueK482_Aque_TESK -------------------------------TV----S-------L---D---------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ---------------------------------------------A---E---------- TESK2_Hsap_TESK -----A-P------GPG------------------------------------------- TESK1_Hsap_TESK -----S-P------FPS------------------------------------------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK -------CDTSLNYHDV------------------------------------------- cdi_Dmel_TESK -----SSC-------F------------EMLAPFFKELAAMQSKAGAQGG---------G LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -----S-P------LTS------------------------------------------- TESK2_Mmus_TESK -----A-P------GPG------------------------------------------- DDB0229851_Ddis_LISK-DD1 -----N-P------TPL------------------------------------------- DDB0229853_Ddis_LISK-DD1 -----Q-P------LPN------------------------------------------- DDB0229854_Ddis_LISK-DD1 -----E-P------YPV------------------------------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 -----S-P------TPP------------------------------------------- DDB0229867_Ddis_LISK-DD1 -----Q-I------TPI------------------------------------------- KinX_Ddis_LISK-DD1 -----T-P------LPW------------------------------------------- KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------LLWTSLIYASI------------------------------------------- CC1G_09729_Ccin_LISK-DD1 LTIRPS-P------DPN------------------------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -----SGC------GP------------ERVDP---------------SSYWKNIG---F AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -----K-P------LRTFENQSGPARESDRLKPV---------------QI--HLQGAHF TESK2_Hsap_TESK T--MPLA---DWQEPL---A----------------------------PPI--------- TESK1_Hsap_TESK TQ-LPLV---TTPETLVQPG----------------------------TPA--------- LIMK2_Hsap_LIMK -----------------------L------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK NN-LPAA---QEDENTVKPGKEELLEESTNKPSNQESQHHRLAIDDMRTRL--------- cdi_Dmel_TESK TSTEETST--GNKASA---A----------------------------T-P--------- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK TQ-LPLV---TTPDILVQPE----------------------------TPV--------- TESK2_Mmus_TESK S--TTLA---DCQEPL---A----------------------------MSS--------- DDB0229851_Ddis_LISK-DD1 --------------------------------------------------TTTTTTTTAT DDB0229853_Ddis_LISK-DD1 --------------------------------------------------I--------- DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 --------------------------------------------------THSEYKDIKS KinX_Ddis_LISK-DD1 --------------------------------------------------D--------- KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK GL---------------------VLEN--------------------STRC--------- CC1G_09729_Ccin_LISK-DD1 --------------------------------------------------R--------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK YKTPSLTD--GKTTPL---T----------------------------PSS--------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK NP-VPLIYQETTPTSQGEPT----------------------------PKT--------- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ATTTSS-----------------------------------SSTNSKVTTNSTSLPTTTT DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ----------------------------------------------VICENC-------- DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 AFTLIRETSNYIQSQLEMSFEHSHIMSIDIMLQKKDNQSLMQ------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK -----------RRWR-------------------------SL------------------ TESK1_Hsap_TESK -----------RRCR-------------------------SL------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK -----------NQCR-------------------------SKFEHLEEASRRNFNQSQHS cdi_Dmel_TESK -----------SEPK-------------------------SL------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -----------RRCR-------------------------SL------------------ TESK2_Mmus_TESK -----------RRWR-------------------------SL------------------ DDB0229851_Ddis_LISK-DD1 TTTTTTATTSSSSLS-------------------------SI------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ---------------------------------------SI------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ---------------------------------------SM------------------- DDB0229867_Ddis_LISK-DD1 ----------SGRWFIRQGQFTELSSNKQYYLFLLSDICLI------------------- KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK -----------VEVL-------------------------HSSQS--------------- CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -----------THFR-------------------------QI------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -----------QRIL-------------------------IL--------------Y--- TESK2_Hsap_TESK --------------------------------PGSPEFLHQEACPFVG------------ TESK1_Hsap_TESK --------------------------------PSSPELPRRMETALPG------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK MKNFFKTPPVALKMFQRLEHEAAALNGGNNCPPPPPRTQRINQTPIFGRKNPPVAIVGQK cdi_Dmel_TESK --------------------------------PVSPHMTRKYSAIELR------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --------------------------------PSSPELPRRMETALPG------------ TESK2_Mmus_TESK --------------------------------PGSPEFLHQ-ACPFMG------------ DDB0229851_Ddis_LISK-DD1 --------------------------------GKPPQSTYKVP----------------- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ---IFR------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK --------------------------------SDSSEVSFQ------------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --------------------------------SNDPQ----------------------- TESK2_Hsap_TESK ------------------RE--------ESLSDGPPP-------------RLSS------ TESK1_Hsap_TESK --------------------------------PGPPA--V----GPSAEEKMEC------ LIMK2_Hsap_LIMK -------LDMES------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK LQHAESLEDLASSGVAKQLA-----------TPAPKR--S----KATA-T---T------ cdi_Dmel_TESK ------------------LPQRISNAAPPAVTSAPPPSIA----LPT-DE-DDC------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --------------------------------PGPSP--M----GPT-EERMDC------ TESK2_Mmus_TESK ------------------CE--------ESLSDGPPP-------------RLSS------ DDB0229851_Ddis_LISK-DD1 --------------------TTI----------------N-----PST------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ---------------------------------------I-------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ---------------------------------------S-----P-------------- DDB0229867_Ddis_LISK-DD1 ---------------------------------------T-----K-------------- KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ---------------------------------------VPEHVLPAT------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------LP-------SPSFAWAPPPSP------ST-S----------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------VSSLPPD--V----RHTQDEYLKRVSDFVQ TESK2_Hsap_TESK ------------------------LKYRVKEI---------------------------- TESK1_Hsap_TESK ------------------------EGSSPEPE---------------------------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------KG-GQSSN---------------------------- cdi_Dmel_TESK ------------------------DDCNSEGEDPDGGGNCADAESSSDDSAVRPSTVPTA LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------EGSSPEPE---------------------------- TESK2_Mmus_TESK ------------------------LKYGVREI---------------------------- DDB0229851_Ddis_LISK-DD1 ------SQRVITIPSRIVTS-----------------------------------TATAQ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK TLQMFSTVSGTDGRSYSAYKCIYDV----DES---------------------------- TESK2_Hsap_TESK -----------PPF-R----------------AS------AL------------PAAQ-A TESK1_Hsap_TESK -----------PPG-P----------------AP------QL------------PLAV-A LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK -----------PPL-F----------------LPP-----SL------------NISV-A cdi_Dmel_TESK RKYRANSLYAHPLF-RGSNGTSMKSTSTGEFESP------TLLKASASTITLTASVGATN LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -----------PPG-L----------------AP------QL------------PLAV-A TESK2_Mmus_TESK -----------PPF-R----------------TS------AL------------SAAS-G DDB0229851_Ddis_LISK-DD1 PKSRSNSNPPK---------------------PT------VVISNSNNNFN--------- DDB0229853_Ddis_LISK-DD1 ----------------------------------------------------DYG-GQNK DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 PTSVK-SY-----------------------------------HPNNNNNNIN----INN DDB0229867_Ddis_LISK-DD1 PIKSK-SS-----------------------------------KYNNN-NNIN----TNN KinX_Ddis_LISK-DD1 ----------------------------------------------------QHFEKQ-- KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK -----------TLFNL----------------ISRLFSRLWN------------VVSL-L CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -LYRLSLT---SPI-D----------------TP------SH------------QVGA-S AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -----------QRE-H----------------IQ--------------------NFNV-W TESK2_Hsap_TESK --------------------HE-------------------------------------- TESK1_Hsap_TESK --------------------TDNF------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK -----------LNSNGNVTTTTNT------------------------------------ cdi_Dmel_TESK --------------------S--------------------------------------- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --------------------TDNF------------------------------------ TESK2_Mmus_TESK --------------------HE-------------------------------------- DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 --------------------RQNN------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 --------------------TNTN------------------------------------ DDB0229867_Ddis_LISK-DD1 --------------------NNNN------------------------------------ KinX_Ddis_LISK-DD1 --------------------KESENKVEQEETNVVVANSQETEQQQQQQQQPKEEEEEEP KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK LQRVHCTRSAGSDLNENVT-YPNQ------------------------------------ CC1G_09729_Ccin_LISK-DD1 ---------------------TSD------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK --------------------R--------------------------------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --------------------SFEN------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ---------------------------------DIVKPSS-------------------- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 TKVEDVKVETEEQTKEEHDVKVDEESTKVDEPVDE--PTKVEESVEQVKAEEPNKVEELV KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 EEVKVEEEPTNVEEVKAEEPVEEVKVEEPVEEVKAEEPVEEVKAEEPVEEVKTEEPVEEV KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 ------------------------------------------------------------ KinX_Ddis_LISK-DD1 KVEEPVEEVKVEEPVEEVEAEESVQEPVEEVKVDEPTKVEEPTKVEEPIEEVKVEEPTKV KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK --------------AM-DCSILQ--E--------------E------------------- TESK1_Hsap_TESK --------------IS-TCSSAS--Q--------------P----WSPRSG-----PV-- LIMK2_Hsap_LIMK ----------------------D--D--------------A----WASRVK-----EL-- LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK --------------NS-SCPPSA--S--------------D----WLPKKH-----KL-- cdi_Dmel_TESK --------------CE-DLTES------------------ARKSKEQASSG-----AT-- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --------------IS-TCSSAS--Q--------------P----WSPRSG-----PP-- TESK2_Mmus_TESK --------------AM-DCSNPQ--E--------------E------------------- DDB0229851_Ddis_LISK-DD1 ------------TIVN-QNKTTT---------------------------Q-----PTT- DDB0229853_Ddis_LISK-DD1 --------------IF-NPSFFT---------------------------P-----PP-- DDB0229854_Ddis_LISK-DD1 --------------------------------------------------P-----PP-- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 --------------IN-NNKISS---------------------------S-----PP-- DDB0229867_Ddis_LISK-DD1 --------------LT------S---------------------------S-----AT-- KinX_Ddis_LISK-DD1 EESIEEVKVEEPTKVE-EPVEEI---------------------------K-----PEEP KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK --------------NGGPTKSLQHGDTPSEVLRNTSTRVAD----LVP------------ CC1G_09729_Ccin_LISK-DD1 --------------IS-HASTAS---------------------------VDPLESP--- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK --------------EG-SLSSP------------------E----HSPITG-----ED-- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --------------LE-TCDAII--L--------------L----MSPSIG-----EV-- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK --LNNNP----------------------------------------------------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK --AAVQA----------------------------------------------------- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --LNNNP----------------------------------------------------- TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 --LINA------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 --VKNS------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 --QTNSNKDLSTSINQSTSNANS------------------------------------- KinX_Ddis_LISK-DD1 TKVEESVEDVKVEDVKVEEVKAEEPTKAEESVEDVKVEEPIKVEEPVKVEEPVKVEEPVK KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK --SDHTP----------------------------------------------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --LRGRS----------------------------------------------------- TESK2_Hsap_TESK -------------------------------------------NGFGSRP--QGTSPCPA TESK1_Hsap_TESK -----------------------------------PAVVVNSPQGWAGEPWNRAQHSLPR LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ----------------------------------------TLPLPSAQQQRTSSNHRLPM cdi_Dmel_TESK -----------------------------------LPTPMSGC-STRLVETPVSVSSCTD LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -----------------------------------PAVVVNSPQGWAREPWNRAQHSLPR TESK2_Mmus_TESK -------------------------------------------NGFGPRL--KGTSLCTG DDB0229851_Ddis_LISK-DD1 ------------------PQ---------------------------------------- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------------------PK---------------------------------------- DDB0229867_Ddis_LISK-DD1 --------------DNSGNN---------------------------------------- KinX_Ddis_LISK-DD1 VEEPIKVEEPIKVEE--------------------------------------------- KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK -----------------------------------------------------------I CC1G_09729_Ccin_LISK-DD1 -------------------SIVSIATLDSYRTANTGESVISSTY---------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -----------------------------------SPDPISGN-QFDLEDWNIIRATCTN AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -----------------------------------PVL--EMEKGVADSH--TLINVLPR TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK LELD-----------ELKNTCDLNELKNSCEQ--------------------LPL----- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ----------------------KV--T----TP--------------------------- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ----------------------SNRFSN---GSLKQQFQQYQQQ--------------QQ DDB0229867_Ddis_LISK-DD1 ----------------------NNNLIN---SKYYYRLKTIINL--------------KE KinX_Ddis_LISK-DD1 ----------------------------------PIKVEEPIKV--------------EE KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ----------------------A------------TEGGSTIRSLHAPGHAVLPTVHRF- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK MSLV-----------EE------------------------------------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK KRVIPVYLNMPKVADW------------------------------------LPVFLKST TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK KTNL-----------------------------TRRDSIESGFFSCFNEESDAAITN--- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229853_Ddis_LISK-DD1 --NSKSMMDLKQSSA--------------------------------------------- DDB0229854_Ddis_LISK-DD1 --TTSEYLDVKDIHSTELARQITIINSFYFNRIKAREFIEYIWEKCGEESTTTPYVGTSF DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 QL----------FLN--------------------------------------------- DDB0229867_Ddis_LISK-DD1 EV----------SMR--------------------------------------------- KinX_Ddis_LISK-DD1 PIKVEEPVKVEVASP--------------------------------------------- KinY_Ddis_LISK-DD1 ----EDELDKEEE----------------ENRNKVNNLKEKMLLVMGEFDIYINKVGKEL LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------EE---------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK PSY---------------------------------------F----------------- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 -------------------------VN-------K------------------------- DDB0229853_Ddis_LISK-DD1 --VDE--------------------DE-------D------------------------- DDB0229854_Ddis_LISK-DD1 VEVVP--------------------AE-------NIHKFVRKCNNLARFVSTEILKQTKL DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 --INE--------------------DD-------K------------------------- DDB0229867_Ddis_LISK-DD1 --INPDISNGVLFIGPNKTYKWLLPND-------E------------------------- KinX_Ddis_LISK-DD1 --VV------------------------------Q------------------------- KinY_Ddis_LISK-DD1 LLVSE--------------------ED-------HISQKYDEC----------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 --------------------------TLLKPGTKP------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK -----------------------NSFGRQLNGIGSLGFGCGGGGNSSNCCYEKL------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 --QIQPLHKS----------------------------------------------NE-- DDB0229853_Ddis_LISK-DD1 --EDE----------------------------------------------------D-- DDB0229854_Ddis_LISK-DD1 QKRV-----------------------------------------------------ATI DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 --ELEELSKS----------------------------------------------ID-- DDB0229867_Ddis_LISK-DD1 --EAKDWVNDFERTTILIYRNNPNGGGSNNNSIGGGGGGRGGSGNNSNNGSIDLTEIN-- KinX_Ddis_LISK-DD1 --EQP----------------------------------------------------P-- KinY_Ddis_LISK-DD1 -RKV-----------------------------------------------------IEI LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 --KKV--------------------------SLGGGPGGIGGAGGTA------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -------------------------------E-------EGGGGG--------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --------------------------------IDLLGFQSGMST---------------- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK -----------------------------------KTQLMLDACVSADSEINDK------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------SVTVAATT-ATTPTTATS-----T----------------TIKSSPTT DDB0229853_Ddis_LISK-DD1 ----------------------------DV----PS-----------------ELLTSLT DDB0229854_Ddis_LISK-DD1 ERFIEAAEKCLANNDYAAVFSIVEPLV--------------------------------D DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 -------------------------------------------------------ASPQS DDB0229866_Ddis_LISK-DD1 ----------------------------DTFRLHFS----------------PLNISPTQ DDB0229867_Ddis_LISK-DD1 ----------------------------QIHHINNQ----------------AIPLSSSN KinX_Ddis_LISK-DD1 ----------------------------QQ----EE-----------------KPEVVST KinY_Ddis_LISK-DD1 KKV-----------------------L--------------------------------G LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --------------------------------------------VTSEEE---------- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ------------------------------------------------------------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 --------PTSTNQNIEQIKITTPKDEDENKSETNDGGGDTV-SHRRSRSLDIKNSTKAI DDB0229853_Ddis_LISK-DD1 VND---IRYS-------------------------------------------------- DDB0229854_Ddis_LISK-DD1 QSIERLSD---TWR-----------------N---V---------SQRN----------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 --------TSS------------------------------------------------- DDB0229866_Ddis_LISK-DD1 --------NNNNNN-----------------NNSNNNNG-NV-NHNHHH----------- DDB0229867_Ddis_LISK-DD1 NNI---T-NNN----------------------SINNNI-IMNNNN--N----------- KinX_Ddis_LISK-DD1 STI---TIAS-------------------------------------------------- KinY_Ddis_LISK-DD1 EVI---ES---------------------------------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK ---LA----------------------SLCRCCYYATSTSNAAVTAAAAAAQQQQQSHLL LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 IKKFEELTRF------------------------------------------SSQQS--- DDB0229853_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229854_Ddis_LISK-DD1 ------LATFEHLKSIVSKENDHKKYRELLPDAKPPCI--------------PNIHLLLD DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ------LNQH------------------------------------------SHINGHLI DDB0229867_Ddis_LISK-DD1 ------NNKD------------------------------------------TEGKGFIK KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 --------------DMS------------------------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------------------------------------ AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK N--DTSSTSSSVLLIDNDPAVIGGNTSSSTALDSMDDLDADIVASRRTHQRRYTCHHALL LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ----N-----------------------------------------------------LV DDB0229853_Ddis_LISK-DD1 --NP-------------------------------------------------------- DDB0229854_Ddis_LISK-DD1 ELS--------------------------------------------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 --SPT-----------------------------------------------------II DDB0229867_Ddis_LISK-DD1 --R-F-----------------------------------------------------RL KinX_Ddis_LISK-DD1 --SP-------------------------------------------------------- KinY_Ddis_LISK-DD1 --N--------------------------------------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ----G-----------------------------------------------------VV AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------ILTDRD------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -----FG-RRSYLLLDEDPNL-----------KEMRDL---------------------- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------------------------------------------------------ LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK ------------------------------------------------------------ cdi_Dmel_TESK SGNGS-ESQMAATA------------SL-INRLALDSEIHTLLQRSPFATNQLLYCKNRT LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------------------------------------------------------ TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 HQPSSSSSSTKQPPTSQFLQNP----RM-EA------------KLSFAQ----------- DDB0229853_Ddis_LISK-DD1 ---KSF-AATISTP---------------------------------------------- DDB0229854_Ddis_LISK-DD1 -------FIETSSPRL----L----PGGIVN------------------F---------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 -----------------VNS---------------------------------------- DDB0229866_Ddis_LISK-DD1 SSSST-TSSSTSTPS------------L-V-------------SLTS------------- DDB0229867_Ddis_LISK-DD1 SFSA-----GTSTPER----KT----SL-V-------------NMSPSTT---------- KinX_Ddis_LISK-DD1 ---QQSSNSPPSTP-----------------------------VKQPQQ----------- KinY_Ddis_LISK-DD1 -------SQQSNTPRK----NSNVTN---------------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 TQ--SSVETSVWNPLEIFF----------------------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------------------------------------------------------ TESK2_Hsap_TESK --------------------------------------G----------ASEEM------ TESK1_Hsap_TESK --------------------------------------A----------AALE------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK --------------------------------------C----------NNKG------- cdi_Dmel_TESK SSIYTDSSDDISSLAGSDSLLWD-----D-RSFTALPST-RSAQIAKIVEYFER------ LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK --------------------------------------A----------AALE------- TESK2_Mmus_TESK --------------------------------------A----------ASEEM------ DDB0229851_Ddis_LISK-DD1 ----------------------E-----T-LVFEKSPS---------------------- DDB0229853_Ddis_LISK-DD1 -------------------------------------N-LN--YA----TALD------- DDB0229854_Ddis_LISK-DD1 -FHYRQL-SRK--------IL-QSQQLQS-HCFRPIPS-IQ------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229866_Ddis_LISK-DD1 ---------------------------------------------S---RDHH------- DDB0229867_Ddis_LISK-DD1 -SSLNNI-DSN--------YNNN-----N-NNVTNTPI-KS-VTSS---PSIHYTPVNDN KinX_Ddis_LISK-DD1 -QEIEVN-STP--------IK-Q-----Q-QQQQQTPT-QQ--TQT---PTKQHTEI--- KinY_Ddis_LISK-DD1 -----SR-VAL--------FL-KSMERSLNEIYSSSDVLKQ------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK --------------------------------------L----------KNRQ------- CC1G_09729_Ccin_LISK-DD1 ------S-SGL--------LI-------S-KCDLCAKRI-G------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK -------------------------------GRERIE----------------------- AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --------------------------------------L----------AVLR------- TESK2_Hsap_TESK -EVEE-----------RPAGSTPA------------------------------------ TESK1_Hsap_TESK -RTEP-----------SPPPSAPREPDEGLPCPGCCLGPFSFGFLSMCPRPT--P----- LIMK2_Hsap_LIMK -----------------------------------LVDC---------YKPT--EAFI-- LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK --KTL-----------K--PLPSRTGSQGIP----ASNC---------VSPT--RSSRPG cdi_Dmel_TESK -KRQD-----------SSPPSVHHRNGNGTVAAAVAASALGSNYLSYESRRY--S----- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK -RTEP-----------SPPPSAPREPEEGLPCPGCCLGPFSFGFLSMCPRPT--P----- TESK2_Mmus_TESK -EVEEE----------RPR-RASV------------------------------------ DDB0229851_Ddis_LISK-DD1 -T-SPKSLD-------IPT--SSSL----------------------------------- DDB0229853_Ddis_LISK-DD1 -Q-DPP----------KPL--SQSA----------------------------------- DDB0229854_Ddis_LISK-DD1 -----K-----------VL----------------------------------------- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 --------S--------FS--NSSL----------------------------------- DDB0229866_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229867_Ddis_LISK-DD1 NQ-QPQ----------LPS--QPNE----------------------------------- KinX_Ddis_LISK-DD1 -N-VQP----------TPT----------------------------------------- KinY_Ddis_LISK-DD1 -----R-----------IV----------------------------------------- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK --KGP-----------G--PGAEDPESQGARKKTLLANELEETELDKLHNPNINRVLL-- CC1G_09729_Ccin_LISK-DD1 ---WKPFLE-------CDD--CGLR----------------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK --REPP-PENPTTVFAVPPPKSSDLKSQGIPTK----------YLDLVTRMI--P----- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK ------------AVA-----------------RY-------------------------- LIMK2_Hsap_LIMK ------------------------------------------------------------ LIMK1_Hsap_LIMK ------------------------------------------------------------ LIMK1_Dmel_LIMK SPTKHLAQRHTAATAQ----------------RLTNAAATHQQQHQQQSSKTTRLNILSP cdi_Dmel_TESK ------------DFK-----------------RH-------------------------- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ------------------------------------------------------------ TESK1_Mmus_TESK ------------AVA-----------------RY-------------------------- TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 ------------------------------TSN--------------------------- DDB0229853_Ddis_LISK-DD1 --------------------------------C--------------------------- DDB0229854_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 ------------------------------GSN--------------------------- DDB0229866_Ddis_LISK-DD1 --------------------------------H--------------------------- DDB0229867_Ddis_LISK-DD1 --------------------------------E--------------------------- KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 ------------------------------------------------------------ LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ------------------------------------------------------------ CC1G_09729_Ccin_LISK-DD1 ------------------------------THV--------------------------- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK ------------HIWDRVGLKLGFTLMEIESIRS-------------------------- TESK2_Hsap_TESK ------------------------------------------------------------ TESK1_Hsap_TESK -------------------------------------------R------N--LNCE--- LIMK2_Hsap_LIMK ---------------------------------------SGL------------------ LIMK1_Hsap_LIMK ----------------------------------------GF------------------ LIMK1_Dmel_LIMK EKVHRLGARLTDQKQKMREEAAATASSVGGAGCAAGTAAGSLNG-----HRTIGS----- cdi_Dmel_TESK -------------------------------------------L------N--ADGL--- LIMK2_Mmus_LIMK ------------------------------------------------------------ LIMK1_Mmus_LIMK ----------------------------------------GF------------------ TESK1_Mmus_TESK -------------------------------------------R------N--LNCE--- TESK2_Mmus_TESK ------------------------------------------------------------ DDB0229851_Ddis_LISK-DD1 -------------------------------------------S------N--SS----- DDB0229853_Ddis_LISK-DD1 -------------------------------------------A------T--VL----- DDB0229854_Ddis_LISK-DD1 --------------------------------------------------T---K----- DDB0229863_Ddis_LISK-DD1 ------------------------------------------------------------ DDB0229865_Ddis_LISK-DD1 -------------------------------------------G-----SN--SS----- DDB0229866_Ddis_LISK-DD1 -------------------------------------------H-----HI--SV----- DDB0229867_Ddis_LISK-DD1 -------------------------------------------F-----QF--TV----- KinX_Ddis_LISK-DD1 ------------------------------------------------------------ KinY_Ddis_LISK-DD1 --------------------------------------------------K--ED----- LIMK_Spur_LIMK ------------------------------------------------------------ Tesk_Spur_TESK ---------------------------------------NGR------------------ CC1G_09729_Ccin_LISK-DD1 -------------------------------------------KCGDLAP---RD----- AqueK481_Aque_LIMK ------------------------------------------------------------ AqueK482_Aque_TESK ------------------------------------------------------------ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK -------------------------------------------R------N--KDDPEQS TESK2_Hsap_TESK ---------------------------------------T---FSTSGIGL---QTQGKQ TESK1_Hsap_TESK --------------------------AGSL-LC---HRGH---HAKPPTPS---LQLPGA LIMK2_Hsap_LIMK --------------------------------LDKI-RA-------MQK------LSTPQ LIMK1_Hsap_LIMK --------------------------------WETYRRG-------ESG-L---PAHPEV LIMK1_Dmel_LIMK --------------------SGTPNS--A--VGERRRRAA---P--SPP-V---RTHFNT cdi_Dmel_TESK ----------------CFDLDKKPAQQRMM-VC---EGAV---KSKLPIFD---KKKQQQ LIMK2_Mmus_LIMK ----------------------------------TV-SM-------EYG------LTRDS LIMK1_Mmus_LIMK --------------------------------WETYRRG-------ESS-L---PAHPEV TESK1_Mmus_TESK --------------------------AGSL-LC---HRGH---HAKPPTPS---LQLPGA TESK2_Mmus_TESK ---------------------------------------Y---FSISGISL---QTQAKQ DDB0229851_Ddis_LISK-DD1 --------------------IPAPSS---------------------PTKK---TFWNKP DDB0229853_Ddis_LISK-DD1 --------------------GGIPP------MQ---PK-------KKPNNK---NKKKKK DDB0229854_Ddis_LISK-DD1 ----------------------PPSE--LF--------DD---ELIKNNSL---KCEPPV DDB0229863_Ddis_LISK-DD1 ---------------------------------------------------------EEN DDB0229865_Ddis_LISK-DD1 --------------------GTSTSS--G-------GK-------KRSQKR---KSWKCL DDB0229866_Ddis_LISK-DD1 --------------------TSSPTN--IKPLS---SSIASNSSVFTPLGS---GLTRTV DDB0229867_Ddis_LISK-DD1 --------------------PTTPSD--KKKK---------RGSFSSKLKR---LSITFS KinX_Ddis_LISK-DD1 ---------------------KTPP------LP---PQTNEKIPLISPNNKSNRGCCSCF KinY_Ddis_LISK-DD1 ----------------------DLVE--SL-LL---ARVV---SKIKKI-H---LSSLDI LIMK_Spur_LIMK ----------------------------------------------HIS-P---TEDPPP Tesk_Spur_TESK --------------------------------MSQ-KRVS---FSLQNSID---RDEGDP CC1G_09729_Ccin_LISK-DD1 ----------------------CGMR--A--VM---NGHQ---HSTPVEMK---KISQSD AqueK481_Aque_LIMK ---------------------------------D--------------D-H---NQHELD AqueK482_Aque_TESK ---------------------RRP-------LF-----------N--RTSC---STPNLQ AqueK483_Aque_TESK ------------------------------------------------------------ AqueK484_Aque_TESK IHSMFSKWQERDGAEATIDILIKV--LQEL-RL---NGVV---YKVKAEVE---KDKQKE TESK2_Hsap_TESK DG TESK1_Hsap_TESK RS LIMK2_Hsap_LIMK KK LIMK1_Hsap_LIMK PD LIMK1_Dmel_LIMK RC cdi_Dmel_TESK GG LIMK2_Mmus_LIMK PP LIMK1_Mmus_LIMK PD TESK1_Mmus_TESK RS TESK2_Mmus_TESK DG DDB0229851_Ddis_LISK-DD1 KK DDB0229853_Ddis_LISK-DD1 KL DDB0229854_Ddis_LISK-DD1 SL DDB0229863_Ddis_LISK-DD1 YD DDB0229865_Ddis_LISK-DD1 IN DDB0229866_Ddis_LISK-DD1 QS DDB0229867_Ddis_LISK-DD1 KD KinX_Ddis_LISK-DD1 IQ KinY_Ddis_LISK-DD1 NN LIMK_Spur_LIMK KT Tesk_Spur_TESK NP CC1G_09729_Ccin_LISK-DD1 SK AqueK481_Aque_LIMK TV AqueK482_Aque_TESK TC AqueK483_Aque_TESK KL AqueK484_Aque_TESK KK