Kinase Family TAM

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Kinase Classification: Group TK: Family TAM

Vertebrate-specific family of receptor tyrosine kinases. This family was named "Axl" until 2016. TAM represents the three human members: Tyro3, Axl, and Mer

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Evolution

Domain Structure

Function

References

  1. Exposito JY, Larroux C, Cluzel C, Valcourt U, Lethias C, and Degnan BM. Demosponge and sea anemone fibrillar collagen diversity reveals the early emergence of A/C clades and the maintenance of the modular structure of type V/XI collagens from sponge to human. J Biol Chem. 2008 Oct 17;283(42):28226-35. DOI:10.1074/jbc.M804573200 | PubMed ID:18697744 | HubMed [Exposito]