Gene IRAK-0_bk (S.moellendorffii)

IRAK-0_bk

Species: S.moellendorffii
Alias: IRAK-0_bk
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_bk.AA Protein None 556 None Fasta, JSON
IRAK-0_bk.NA RNA None 1671 None Fasta, JSON
IRAK-0_bk.kin_dom Protein Kinase Domain None 198 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_bk.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUF26 IRAK-0_bk.AA DUF26 85-131 28 8.4e-08 25.64 Pfam 11-55 (55) Show / Hide 
Range on Protein: 85-131
Range on HMM: 11-55/55
Sequence Identity: 28% (14 aa)

MSQGDCGQCFNIARDGI-DEAAPLTVGAQYWVNSSSYRCYLRFENYN-F
.| .|| .|.. | ...  .  |  .|.. |    . .||||...|. |
LSPSDCRDCLATAVRQMLPQCCPNRQGGRIW----YDWCYLRYSDYPNF
Kinase IRAK-0_bk.AA TKL 242-433 25 4.7e-64 219.11 In-house 1-285 (364) Show / Hide 
Range on Protein: 242-433
Range on HMM: 1-285/364
Sequence Identity: 25% (74 aa)

LGQGGFGPVYKGVLTD---------GSEVAVKKLSLHSSQGN---------------------------QEFVNEVNIITGIQHRNLTRLRGYSVKGDE-
.|.|||| ||||..           | .|||||.. |... .                           .....|....  ..| |. .. ||.  ..  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEYLPNGSLDRTLTNSNGKIVLDWPTRYNIAIGVARGLAYLHEES-----QIQIIHRDIKASNILLDKDLT-------------
              .|.|| |.|||  .|.         |. | ..|...|||..||| .        .|||||.| .|||.|...|             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKISDFGISKLFDQDRTSVDTK------------------IAGTYGYMAPEYAMGG----------------RLTVKADVFSFGVLLLEIICG
 .||.|||.|. ..|.  . ||.                  . ||...||||  .|                   . |.||.|||..| ||...
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTR
Kinase IRAK-0_bk.AA IRAK 236-435 36 1.4e-60 207.62 In-house 1-222 (317) Show / Hide 
Range on Protein: 236-435
Range on HMM: 1-222/317
Sequence Identity: 36% (81 aa)

FGEQNKLGQGGFGPVYKGVLTDGSE--VAVKKL----SLHSSQGNQEFVN---EVNIITGIQHRNLTRLRGYSVKGDERLLVYEYLPNGSLDRTLTNSNG
| . |..|.|||| ||.|.. .. .  .|||||    ..   .  |.|     |. . . ..| |.  | ||. ....  |||.|.|||||   |   .|
FHKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDG

KIV---LDWPTRYNIAIGVARGLAYLHEES-QIQIIHRDIKASNILLDKDLTPKISDFGISKLF----DQDRTSV---DT-KIAGTYGYMAPEYAM--GG
      | |..|  |..| |.|. .||. .  . |||.||| .|||||...||||.|||         .  ....    | .. ||  ||.||.     |
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

RLTVKADVFSFGVLLLEIICGMK
.||.| ||.|||. |||.. | .
QLTKKTDVYSFGIVLLEVLTGCR
Kinase IRAK-0_bk.AA Pkinase 236-433 30 6.3e-47 167.01 Pfam 1-208 (293) Show / Hide 
Range on Protein: 236-433
Range on HMM: 1-208/293
Sequence Identity: 30% (66 aa)

FGEQNKLGQGGFGPVYKGVLTDGSE-VAVKKLSLHSSQGNQE--FVN--EVNIITGIQHRNLTRLRGYSVKGDERLLVYEYLPNG----SLDRTLT-NSN
.    |.|.|.|| |||..  . .. ||||......   ...   ..  |. |   ..| |  ||...   .|.  .| ||...|    .| . ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKIVLDWPTRYNIAIGVARGLAYLHEESQIQIIHRDIKASNILLDKDLTP----KISDFGISKLFDQDRTSVDTKIAGTYGYMAPEYAM-GGRLTVKADV
|.. ... .  ...  ..|||.|.|..    |||||.| .|||.|.. ..    ||.|||..|.||  . |  | ..||..|||||  . |   . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSFGVLLLEIICG
.|.|..| | .||
WSCGCILYEMLCG
Kinase IRAK-0_bk.AA TKL-Unique 240-431 33 1.4e-45 157.7 In-house 3-222 (290) Show / Hide 
Range on Protein: 240-431
Range on HMM: 3-222/290
Sequence Identity: 33% (75 aa)

NKLGQGGFGPVYKGVLTDGSEVAVKKLSLHSSQGNQ---EFVNEVNIITGIQ-HRNLTRLRGYSV----KGDERLLVYEYLPNGSLDRTLT----NS---
||.|.||.|.||||.   |..||.|.... ... |.   || ||||..  .. | |.... ||..    .  .. .| ||.| |||.  |.    |.   
NKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

NGKIVLDWPTRYNIAIGVARGLAYLHEESQIQIIHRDIKASNILLDKD-----LTPKISDFGISKLFDQDRTSVDTKI--------AGTYGYMAPEYAMG
| .. |..  |...|| .|.|. ||| ..   |||||.| ||.|.| .     .  ||.|||.||. ... ..  . .         |.. .||||  ..
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GRLTVKADVFSFGVLLLEII
     . |.||.|||. | ||.
NFCQYSEKSDVYSFGIVLWEIA
Kinase IRAK-0_bk.AA MLK 236-431 28 1.9e-43 148.61 In-house 1-230 (291) Show / Hide 
Range on Protein: 236-431
Range on HMM: 1-230/291
Sequence Identity: 28% (66 aa)

FGEQNKLGQGGFGPVYKGVLTDGS----EVAVKKLSL------HSSQGNQEFVNEVNIITGIQHRN-----LTRLRGYSVKGDERLLVYEYLPNGSLDRT
. .. ..| |.|| |.||.         .||||.          ..   ..|  |...   ..|.|        . . .  . . ..| ||...||| . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LTNSNGKIV-----------LDWPTRYNIAIGVARGLAYLHEESQIQIIHRDIKASNILLD------KDLTPKISDFGISKLFDQDRTSVDTKIAGTYGY
| . ..|.             |     |.|  .|||..|||.. . .|||||.| .|||.|      ...| ||.|||.|. . |   .  .. |||| .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPEY---AMGGRLTVKADVFSFGVLLLEII
||||    . ... . |.||.|.||.| |..
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEML
Kinase IRAK-0_bk.AA Dicty4 239-430 36 2.2e-43 142.63 In-house 4-210 (277) Show / Hide 
Range on Protein: 239-430
Range on HMM: 4-210/277
Sequence Identity: 36% (78 aa)

QNKLGQGGFGPVYKGVLTDGSEVAVKKLSLHSSQGN------QEFVNEVNIITGIQHRNLTRLRGYSV----KGDERLLVYEYLPNGSLDRTLTN----S
....|.|.|| ||||    |.||||||| .|  . |      .|| .||.|   |.| |.  . |..     .  . . | ||.| |.| . | .     
EQRIGKGSFGEVYKGTWR-GKEVAVKKLNNH--NQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

NGKIVLDWPTRYN---IAIGVARGLAYLHEESQIQIIHRDIKASNILLDKDLTPKISDFGISKLFDQDRTSVD--TKIAGTYGYMAPEYAMGGRLTVKAD
  .| ||||..     .|. .|||...||. .   |||||.|..|.| ||... |..|||.|...  . .  |  .  .|| ..||||  |. . . |||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VFSFGVLLLEI
|.||| .| ||
VYSFGIVLWEI
Kinase IRAK-0_bk.AA LISK 241-435 29 5.7e-40 127.43 In-house 1-237 (296) Show / Hide 
Range on Protein: 241-435
Range on HMM: 1-237/296
Sequence Identity: 29% (71 aa)

KLGQGGFGPVYKGVLT-DGSEVAVKKLSL----HSSQGNQEFVN-EVNIITGIQHRNLTRLRGYSVK-GDERLLVYEYLPNGSLDRTLTNSNG-KIVLDW
..|.|.|| |||| .  .|...|.|...          .| |.. || ..  ..|.|  .  | ...  ..  .| ||   | | . | ...  ||.| |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

PTRYNIAIGVARGLAYLHEESQIQIIHRDIKASNILLD----KDLTPKISDFGISKLFDQDRTSVDT-----------------------------K---
| | .|| ..|.|..|||.    .||||| |. |.|..     . . |. |||  ...|... | .                              |   
PQRVKIALDIACGMSYLHSM---NIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

-IAGTYGYMAPEYAMGGRLTVKADVFSFGVLLLEIICGMK
 | ||   ||||   |   . ..||||||..|.|||...|
TICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVK
Kinase IRAK-0_bk.AA Pkinase_Tyr 236-431 31 1.4e-39 134.68 Pfam 1-208 (270) Show / Hide 
Range on Protein: 236-431
Range on HMM: 1-208/270
Sequence Identity: 31% (68 aa)

FGEQNKLGQGGFGPVYKGVLT-----DGSEVAVKKLSLHSSQGN---QEFVNEVNIITGI-QHRNLTRLRGYSV-KGDE--RLLVYEYLPNGSLDRTLTN
     |||.| || ||||...     .. .||||.|  .... .   ..| .|..| . . .| |. || |  . .|.    ..| || |.|.|.  | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

S-NGKIVLDWPTRYNIAIGVARGLAYLHEESQIQIIHRDIKASNILLDKDLTPKISDFGISKLF---DQD-RTSVDTKIAGTYGYMAPEYAMGGRLTVKA
  ..|  |. ..  .... .|.|..||..   ...||||. | |.|...... ||.||| ...    |.  |.. ..|       ||||  . |. |.| 
HREDKQPLTMKDLLQMCWQIAKGMEYLES---KNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK--LPIKWMAPECINYGKFTTKS

DVFSFGVLLLEII
|| |||||. ||.
DVWSFGVLMWEIF
Kinase IRAK-0_bk.AA TK 236-430 17 1.4e-39 129.82 In-house 1-387 (486) Show / Hide 
Range on Protein: 236-430
Range on HMM: 1-387/486
Sequence Identity: 17% (70 aa)

FGEQNKLGQGGFG---PVYKGVLTDGS--------------------------EVAVKKLSLHSSQGNQEFVN--------------EVNIITGIQ----
    .|||.| ||    |||| . ...                          .|||| | .....  .||                |....   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLTRLRGYSVKGDE------------RLLVYEYLPNGS----LDRTLTNSNGKIV------------------------------------------
 | |. || |....|..             ..| || |.|.    |.  | .. .|                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWPTRYNIAIGVARGLAYLHEE--SQI--QIIHRDIKASNILLDKDLT-----------PKISDFGIS
                               |. ...  ..  .|.|..|||.   .    ...|||. | |.|......            ||.||| |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-----LFDQDRTSVDTKIAGTYG----------------------------YMAPEYAM---------GGRLTVKADVFSFGVLLLEI
.     |   .  . |   ...||                            .||||  .          |. | | ||.|||||. ||
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase IRAK-0_bk.AA LRRK 236-431 24 1.1e-38 134.48 In-house 1-276 (351) Show / Hide 
Range on Protein: 236-431
Range on HMM: 1-276/351
Sequence Identity: 24% (70 aa)

FGEQNKLGQGGFG-PVYKGVLTD---------------------------GSEVAVKKLSLH---------SSQG-------------------------
. .....|.|||| .||.. . .                           ...||.||. ..         .| .                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

NQEFVNEVNIITGIQHRNLTRLRGYSVKGDERLLVYEYLPNGSLDRTLTNSN-GK-----IVLDWPTRYNIAIGVARGLAYLHEESQIQ--IIHRDIKAS
 .|| .|| |. . .| |.  | |..   . . .| ||.|.|.|.. | |.   .     ....| ... ||. .|.|..|||        ||||| |  
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKSP

NILLDKDLTP------------KISDFGISKLFDQDRTSVDTKIAGTYGYMAPEYAMGG---RLTVKADVFSFGVLLLEII
|||| .  ..            ||.||||| .|  ....|  .  |. |.||||   ..     | |.|..|||..| |..
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELL
Kinase IRAK-0_bk.AA STE 236-433 22 1.8e-37 129.9 In-house 1-264 (359) Show / Hide 
Range on Protein: 236-433
Range on HMM: 1-264/359
Sequence Identity: 22% (61 aa)

FGEQNKLGQGGFGPVYKGVLTD----------------GSEVAVKKLSLHSSQG-----------------NQEFVNEVNIITGIQ--HRNLTRLRGYSV
.  . |.|.|.|| |||..  .                |  .|.|...| ...                   |.. .|..|    .  | |  .  |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KG-------DERLLVYEYLPNGSLDRTLT-NSNGKIVLD----------WPTRYNIAIGVARG-LAYLHEESQIQIIHRDIKASNILLDKDLTPKISDFG
|.       ||  .. ||...||||  .  .   .  |.           .    |.  . .| |.|||.     |||||||..||||      |..|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

ISKLFDQ---------------DRTSVDTKIAGTYGYMAPEYAMGGR------LTVKADVFSFGVLLLEIICG
... ...               .. .  . ..||  .||||  ....       ..|.|. |.| ...| ..|
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATG
Kinase IRAK-0_bk.AA Dicty4-Unclassified 239-433 34 2.8e-37 125.23 In-house 4-204 (263) Show / Hide 
Range on Protein: 239-433
Range on HMM: 4-204/263
Sequence Identity: 34% (71 aa)

QNKLGQGGFGPVYKGVLTDGSEVAVKKLSLHSSQGN----QEFVNEVNIITGIQHRNLTRLRGYSVKG----DERLLVYEYLPNGSLDRTLT----NSNG
   .|.| |  |.||.   | .|||||.   . .      |.|  || |   ||| || ...||..           | | .. | |           . 
DQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

KIVLDWPTRYNIAIGVARGLAYLHEESQIQIIHRDIKASNILLDKDLTPKISDFGISKLFDQDRTSVDTKIAGTYGYMAPEYAMGGRLTVKADVFSFGVL
 | ||      .|. .|.|...||      .||||||.||||.||.   || |||||   |   .   | ||||    .||  |.   . |.||.|....
PIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNM--TTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LLEIICG
| | . |
LYELATG
Kinase IRAK-0_bk.AA S_TKc 236-512 22 1.4e-35 125.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 236-512
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

FGEQNKLGQGGFGPVYKGVLTD-GSEVAVKKLSLHSSQGNQEFVNEVNIITGIQHRNLTRLRGYSVKGDERLLVYEYLPN--GSLDRTLTNSNGK---IV
.   .|.|.|.|| |||.. .. | .||.|...       . . .|..|    .| |. .| .. .  |.  .| ||...  |.| . . . ...    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWPTRYNIAIGVARGLAYLHEESQIQIIHRDIKASNILLDKDLTPKISDFGISKLFDQDRTSVDTKIAGTYGYMAPEYAMGGRLTV-KADVFSFGVLLL
..  .   ..  ....|.|.|  |. .|||||.| .|||||.  . ||.|||.....        | . ||  |||||       .  |.|. |.|..| 
FPE-HARFYMYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EIICGMKCRDPRLSPNYDGILEWLWSFHPGGNVEEIVDKELLRSKNYSQTEALRSIHIALLCTHEDEASRPSMSEVVAMF-----LGYL
| .||    .     ... ... .                               ...   | . | . ||.  |. ..        ..
EMLCGYPPFP-----QMQMMFKKIG--------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-0_bk.AA TyrKc 236-508 28 5.9e-35 123.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 236-508
Range on HMM: 1-280/280
Sequence Identity: 28% (85 aa)

FGEQNKLGQGGFGPVYKGVLTDGSEVAVKKLSLHSSQGNQEFVNEVNIITGI--QHRNLTRLRGYSVKG-------DERLLVYEYLPNGSLDRTLTNSNG
     ||| | || ||||...   .||||.|  ..    ..| .| .| . .  .| |. || |. ...       .  ..| || |.|.|.  | .. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KIVLDWPTRYNIAIGVARGLAYLHEESQIQIIHRDIKASNILLDKDLTPKISDFGISKLFDQD--------RTSV----DTKIAGTYGYMAPEYAMGGRL
|  | ...  .... .|.| .|||.    ..||||. | |.|.....| |||||| |.  . |          ..    ..|    .  ||||  . |. 
K--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TVKADVFSFGVLLLEIICGMKCRDPRLSPNYDGILEWLWSFHPGGNVEEIVDKELLRSKNYS--------QTEALRSIHIALLCTHEDEASRPSMSEVVA
| | ||.||||.. ||     .  |     | |. .    . .   | | |..   . .  .         .... .  | . | ||| ..||..||.. 
TTKSDVWSFGVCMWEIF--TYGQQP-----YPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--IMKQCWHEDPEDRPTFSEIHE

MF
 |
CF
Kinase IRAK-0_bk.AA TK 486-508 26 0.000174 10.11 In-house 464-486 (486) Show / Hide 
Range on Protein: 486-508
Range on HMM: 464-486/486
Sequence Identity: 26% (6 aa)

IALLCTHEDEASRPSMSEVVAMF
. . | |.| . ||..|... ..
LMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-0_bk.AA TKL 486-508 26 0.015633 4.95 In-house 342-364 (364) Show / Hide 
Range on Protein: 486-508
Range on HMM: 342-364/364
Sequence Identity: 26% (6 aa)

IALLCTHEDEASRPSMSEVVAMF
..  | ..|  .|||..|..  .
LMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-0_bk.AA Dicty4-Unclassified 490-508 31 0.099107 1.66 In-house 245-263 (263) Show / Hide 
Range on Protein: 490-508
Range on HMM: 245-263/263
Sequence Identity: 31% (6 aa)

CTHEDEASRPSMSEVVAMF
| |.|   ||.| ...   
CWHNDPNKRPTMNQIIQYL
Kinase IRAK-0_bk.AA MLK 496-508 30 0.151562 1.29 In-house 279-291 (291) Show / Hide 
Range on Protein: 496-508
Range on HMM: 279-291/291
Sequence Identity: 30% (4 aa)

ASRPSMSEVVAMF
..|||....|  .
HKRPSFRQIVQHL
Kinase IRAK-0_bk.AA Pkinase_Tyr 488-508 33 0.331009 4.71 Pfam 250-270 (270) Show / Hide 
Range on Protein: 488-508
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

LLCTHEDEASRPSMSEVVAMF
..| |.| . ||..||.. ..
KQCWHYDPEDRPTFSEIHEQL