Gene IRAK-0_m-2 (S.moellendorffii)

IRAK-0_m-2

Species: S.moellendorffii
Alias: IRAK-0_m-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_m-2.AA Protein None 849 None Fasta, JSON
IRAK-0_m-2.NA RNA None 2550 None Fasta, JSON
IRAK-0_m-2.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_m-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-0_m-2.AA TKL 542-800 20 2.5e-63 216.72 In-house 1-364 (364) Show / Hide 
Range on Protein: 542-800
Range on HMM: 1-364/364
Sequence Identity: 20% (78 aa)

LGKGSFATVYKGVLHN---------GCQVAIKQAKACTRSG----------------------------EMFRKELKLLARTHHSCVLNLIGYCEQEK--
.|.|.|..||||....         |  ||.|. |    .                             . ...|.... |..|  .. ..||| ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------------LLVFEFMSRGTLHDNLYSSNSLEWTTRIKISAQAARGLEYLHRYVS-----PSVTHRDVKSSNILLDCDWN--------------AK
              .| |....|.|...|       |  |.... ..|||..|||         | . ||| ||.|||.| .|.              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

VSNFGLSVCG-----PQDNATHLS-----------NLTIVGTPGYLDPEY----------------GNSSQLTTTSDVYSFGVVLLELMSGQKPID-LSR
.. |||| .       .|..|.             . |..|||... ||                  .... .. .||||||.|| |......| . .  
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

EIQSLV-------AWVLDLVER----DEWSSVLDARLAVPLEPEPLYRAVKLALECTKVSGKERPSMSHVAKTL
. . .        ..| |  .|    ..|....  . . . .|  . .  ||. .| .   ..|||.. . |.|
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-0_m-2.AA IRAK 536-800 26 3.6e-49 169.67 In-house 1-317 (317) Show / Hide 
Range on Protein: 536-800
Range on HMM: 1-317/317
Sequence Identity: 26% (83 aa)

YCDDSILGKGSFATVYKGVLHNGC-QVAIK--QAKACTRSGEM---FRK---ELKLLARTHHSCVLNLIGYC-EQEKL-LVFEFMSRGTLHDNLYSSN--
.  |  .|.| |..||.|...|    .|.|   . |..  .|.   |.    |||...| .|  .. | ||| | ... ||...|. |.|.| |   .  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-S---LEWTTRIKISAQAARGLEYLHRYVSP-SVTHRDVKSSNILLDCDWNAKVSNFGLSVCG---PQDNATHL---SNLTIVGTPGYLDPEYGN--SSQ
 .   |.| .|..|.  .|.|...||   .  .. |.|.||.||||| . ..| . |||  .|   .   .. .      ...||  |. ||. .  . |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTTTSDVYSFGVVLLELMSGQKPIDLS-REIQSLVAWVLDLVERDE-WSSVLD------------------------ARLAVPLEPEPLYRAVKLALECT
||. .||||||.||||. .|... .   .| . |.  . .. |      | .                          ... |..|.       .|..|.
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQCACCCG

KVSGKERPSMSHVAKTL
    ..|..|  | ..|
HHRANRRCDMAWVMQQL
Kinase IRAK-0_m-2.AA TKL-Unique 538-732 28 1.9e-42 147.35 In-house 1-233 (290) Show / Hide 
Range on Protein: 538-732
Range on HMM: 1-233/290
Sequence Identity: 28% (67 aa)

DDSILGKGSFATVYKGVLHNGCQVAIKQAKA----CTRSGEMFRKELKLLARTH-HSCVLNLIGYCE----QEK--LLVFEFMSRGTLHDNLY-------
. . .| |....||||. ..| .||||| .       .. . |..|.... . | |  .. ..|||     ...   .| |....|.|.|.|        
FWNKIGEGGYGQVYKGK-WRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

---SSNSLEWTTRIKISAQAARGLEYLHRYVSPSVTHRDVKSSNILLDCD-----WNAKVSNFGLSVCGPQDNATHLSNL------TIVGTPGYLDPEYG
   ... | .  |.|.  ..|.|..|||..  | ..||| ||||.|.| .     ||.|.. ||||    ..|.. ....      | .|.. .. ||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

NS--SQLTTTSDVYSFGVVLLELMSGQK------P
..  .| .. |||||||.|| |. ...       |
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase IRAK-0_m-2.AA Pkinase 536-730 25 7.5e-42 149.07 Pfam 1-209 (293) Show / Hide 
Range on Protein: 536-730
Range on HMM: 1-209/293
Sequence Identity: 25% (54 aa)

YCDDSILGKGSFATVYKGVLHNGCQ-VAIKQAKACTRSGEMFRK-----ELKLLARTHHSCVLNLIGYCE--QEKLLVFEFMSRG----TLHDNLY--SS
|.  ...|.|||..|||.. .. .. ||.|. | .... .. .      |.....| .| ... |....|  ..  .|.|..  |     |.| .   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NSL--EWTTRIKISAQAARGLEYLHRYVSPSVTHRDVKSSNILLDCDWNA----KVSNFGLSVCGPQDNATHLSNLTIVGTPGYLDPEYGN-SSQLTTTS
...  .. . ...  | .|||||.|.    .. |||.|..|||.| . .     |.. |||. .    .     . |..|||.|. ||  . ..  .. .
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGVVLLELMSGQ
|..|.|..| |...|.
DMWSCGCILYEMLCGR
Kinase IRAK-0_m-2.AA LRRK 524-734 22 7.8e-33 113.48 In-house 1-284 (351) Show / Hide 
Range on Protein: 524-734
Range on HMM: 1-284/351
Sequence Identity: 22% (67 aa)

FSASELQAATNNYCDDSILGKGSFA-TVYKGVLHN---------------------------GCQVAIKQAKAC--------------------------
.   |.            .|.|.|. .||.. . .                           .  ||||. . .                          
LKIEEQ------------IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVE

---------TRSGEMFRKELKLLARTHHSCVLNLIGYCEQEKLLVFEFMSRGTLHDNLY---SSN------SLEWTTRIKISAQAARGLEYLHRYVSPSV
         .|.   ||.|. .. . .|.....|.|.| .   .| |... |.|.. |    ..       .. |....||. | |.|.||||.  .|..
DMDQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPI

THRDVKSSNILL---D---------CDWNAKVSNFGLSVCGPQDNATHLS-NLTIVGTPGYLDPEYGN---SSQLTTTSDVYSFGVVLLELMSGQ-KPID
 ||| || ||||   .          . .||.. ||.|       ..| .   . ||.||.. ||  .    .. |. .|.||||..| ||...|  | |
IHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR--MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase IRAK-0_m-2.AA LISK 541-732 26 1.9e-30 95.95 In-house 1-238 (296) Show / Hide 
Range on Protein: 541-732
Range on HMM: 1-238/296
Sequence Identity: 26% (63 aa)

ILGKGSFATVYKGVLH-NGCQVAIKQAKA-----CTRSGE-MFRKELKLLARTHHSCVLNLIGYCEQ-EKLL--VFEFMSRGTLHDNLYSSN----SLEW
..|||.|. |||| .   |  .|||. .      . .. .  . .|.... .  |  ... .| |.. .. |  | |... |.||. | ...     | |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

TTRIKISAQAARGLEYLHRYVSPSVTHRDVKSSNILLD----CDWNAKVSNFGLS-VCGPQDNA------------------------------THLSNL
. |.||.   |.|..|||   |  . ||| || |.|..     .|..||  ||.  .   ..|                               .  . .
PQRVKIALDIACGMSYLH---SMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

TIVGTPGYLDPEYGNSSQLTTTSDVYSFGVVLLELMSGQKP
||.|||    ||  . .. ....||.|||.||.|.  . |.
TICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA
Kinase IRAK-0_m-2.AA S_TKc 536-804 22 3.6e-30 107.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 536-804
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

YCDDSILGKGSFATVYKGVLHN-GCQVAIKQAKACTRSGEMFRKELKLLARTHHSCVLNLIGYCE-QEKLLVFEFMSR--GTLHDNLYSSNS------LE
|    ..|||.|..|||.. .. | .||||. |      |..|.|...| . ||  . .|..... ..  .|.|...   |.|.| . . ..      . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

WTTRIKISAQAARGLEYLHRYVSPSVTHRDVKSSNILLDCDWNAKVSNFGLSVCGPQDNATHLSNLTIVGTPGYLDPEYGNSSQLTT-TSDVYSFGVVLL
  .  .. .| ...|||.|   |  . |||.| .|||||   . |.. |||.              |..||| |. ||     . ..  .|..|.|..| 
E-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELMSGQKPIDLSREIQSLVAWVLDLVERDEWSSVLDARLAVPLEPEPLYRAVKLALECTKVSGKERPSMSHVAK-----TLEEVL
|...|. | .   ..| .   ..                           |  .   | ..  ..||.   . .      . . .
EMLCGYPPFP---QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-0_m-2.AA STE 536-730 21 6.2e-29 99.35 In-house 1-265 (359) Show / Hide 
Range on Protein: 536-730
Range on HMM: 1-265/359
Sequence Identity: 21% (58 aa)

YCDDSILGKGSFATVYKGVLHN----------------GCQVAIKQAKACT------------------RSGEMFRKELKLLARTH--HSCVLNLIGYCE
. . ...|||.| ||||.. |.                |. .|||| . ..                     . . ||.|.. . .  |  . . .|...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

---------QEKLLVFEFMSRGTLH---DNLYSSNS-----------LEWTTRIKISAQAARG-LEYLHRYVSPSVTHRDVKSSNILLDCDWNAKVSNFG
         .|  .. |.|. |.|    .. |. .            .. .  ..|  |  .| |.|||.     . |||.|..||||     .| ..||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LSVCGPQDNA------------THLSNL-TIVGTPGYLDPEYGNS------SQLTTTSDVYSFGVVLLELMSGQ
.. .  ...|            |  ..  |.|||| .  ||  .       .. .| .|..|.| ...|.  |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase IRAK-0_m-2.AA TK 536-677 16 1.6e-28 92.08 In-house 1-298 (486) Show / Hide 
Range on Protein: 536-677
Range on HMM: 1-298/486
Sequence Identity: 16% (48 aa)

YCDDSILGKGSFA---TVYKGVLHNG--------------------------CQVAIKQAKAC-TRSGEMFRK-----------------ELKLLA--RT
      ||.| |    .|||| ....                          ..||.|. |.  . | |.|.                  |.|..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHSCVLNLIGYCEQEK--------------LLVFEFMSRGT----LHDNLYSSNS---------------------------------------------
||  ...|.|.| |..              ..| |.|. |     |.| | ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LEWTTRIKISAQAARGLEYLHRY----VSPSVTHRDVKSSNILLDCDWN-----------AKVSNFGLS
                               |   ... ...|.|.|.||||.     . . . |||.   |.|.. . .           .|.. ||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS
Kinase IRAK-0_m-2.AA Dicty4 536-732 31 3.7e-28 91.16 In-house 1-216 (277) Show / Hide 
Range on Protein: 536-732
Range on HMM: 1-216/277
Sequence Identity: 31% (69 aa)

YCDDSILGKGSFATVYKGVLHNGCQVAIKQA---KACTRSGEM--FRKELKLLARTHHSCVLNLIGYCE----QE--KLLVFEFMSRGTLHDNLYS----
.  ....|||||..||||    | .||.| .   .   .. ..  |||| ....   |  .. . |.|     .    . | |.|..|.|.  | .    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

---SNSLEWTTRIK---ISAQAARGLEYLHRYVS--PSVTHRDVKSSNILLDCDWNAKVSNFGLSVCGPQDNATHLS-NLTIVGTPGYLDPEYGNSSQLT
   | .|.|.....   .   ||||. .||   .  | . ||| ||.|.| | .|..||. ||||    .   .|     | .|||..  ||   .   .
QQQSIKLDWPLIKRAMRMAFDAARGMNWLH---CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQY-MKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

TTSDVYSFGVVLLELMSGQKP
  .|||||| || |.  .| |
EKADVYSFGIVLWEILTRQEP
Kinase IRAK-0_m-2.AA MLK 541-732 27 2.9e-27 91.7 In-house 6-235 (291) Show / Hide 
Range on Protein: 541-732
Range on HMM: 6-235/291
Sequence Identity: 27% (63 aa)

ILGKGSFATVYKGVLHNGC----QVAIKQAKACT----------RSGEMFRKELKLLARTH-HSCVLNLIGYCEQE-K--LLVFEFMSRGTLHDNLYSSN
..|.|||  |.||. .|       ||.|...| .          .  ||. ..|. | .   |.|.  . | | |. .  ..| |... | |.. |.. .
WIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGAR

S--------------LEWTTRIKISAQAARGLEYLHRYVSPSVTHRDVKSSNILLD------CDWNAKVSNFGLSVCGPQDNATHLSNLTIVGTPGYLDP
|                    .... | |||..|||    . . ||| ||.|||.|      .. ..|.. ||.|    |  ... ||    ||. .  |
SKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSN---AGTYAWMAP

EY---GNSSQLTTTSDVYSFGVVLLELMSGQKP
|      ... .  .||.|.|||| |..... |
EVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAK-0_m-2.AA Pkinase_Tyr 542-677 29 1.1e-26 91.01 Pfam 7-158 (270) Show / Hide 
Range on Protein: 542-677
Range on HMM: 7-158/270
Sequence Identity: 29% (45 aa)

LGKGSFATVYKGVLH-----NGCQVAIKQAKACTRSG----EMFRKELKLLART-HHSCVLNLIGYCE--QEK---LLVFEFMSRGTLHDNLYS----SN
||.|.| .||||...     ....||.|  |  . .     |.| .|.|..    ||  ...|.| |   .|    ..|.|.|  | |.| | .     .
LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQ

SLEWTTRIKISAQAARGLEYLHRYVSPSVTHRDVKSSNILLDCDWNAKVSNFGLS
.|   . .....| |.|.|||..       |||.   |.|....  .|.. |||.
PLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLA
Kinase IRAK-0_m-2.AA TyrKc 536-800 24 2.2e-18 68.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 536-800
Range on HMM: 1-280/280
Sequence Identity: 24% (76 aa)

YCDDSILGKGSFATVYKGVLHNGCQVAIKQAKACTRSGEMFRKELKLLART--HHSCVLNLIGYCE---------QEKLLVFEFMSRGTLHDNL-YSSNS
   . .|| | | .||||..    |||.|  |...   |.|..|.... .   || ....|.|.|          .  ..|.|.|. | |.| | .. . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LEWTTRIKISAQAARGLEYLHRYVSPSVTHRDVKSSNILLDCDWNAKVSNFGLSVCGPQD-------NATH-----LSN--LTIVGTPGYLDPEYGNSSQ
| . . .... |.|.| ||||.     . |||    |.|.. .  .|.| ||||  .  |          .      ..  | |  ..    ||  | . 
LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA----PECINYGK

LTTTSDVYSFGVVLLELMS-GQKPIDLS----REIQSLVAWVLDLVERDEWSSVLDARLAVPLE---------PEPLYRAVKLALECTKVSGKERPSMSH
 || |||.||||.. |... ||.|         . | ....| .             |.  | .         |. .|   .. ..| .   ..||..| 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ-----------GYRMPQPPNDYPMSFVCCPDEMY---QIMKQCWHEDPEDRPTFSE

VAKTL
. . .
IHECF
Kinase IRAK-0_m-2.AA LISK-DD1 607-732 34 3.1e-17 59.04 In-house 90-230 (290) Show / Hide 
Range on Protein: 607-732
Range on HMM: 90-230/290
Sequence Identity: 34% (49 aa)

EFMSRGTLHDNLYS-------------SNSLEWTTRIKISAQAARGLEYLHRYVSPSVTHRDVKSSNILLDCD----WNAKVSNFGLSVCGPQD-NATHL
||.. | ||. | .             .  . |. |.||.   | . .|||   | .. ||| || |||.|      | .||  ||.   . |. | . .
EFIEGGDLHWYLKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLH---SKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNN

SNLTIVGTPGYLDPEYGNSSQLTTTSDVYSFGVVLLELMSGQKP
. .||.||..   ||    ..  . .||.|||.||||| .. ||
RHMTICGTDNWMAPEVILGMSYDWSCDVFSFGMVLLELITRKKP
Kinase IRAK-0_m-2.AA LISK-DD1 541-565 56 3e-06 18.88 In-house 1-24 (290) Show / Hide 
Range on Protein: 541-565
Range on HMM: 1-24/290
Sequence Identity: 56% (14 aa)

ILGKGSFATVYKGVLHNGCQVAIKQ
. |||||. ||||.. .|  ||||.
EIGKGSFGKVYKGCY-FGTPVAIKK
Kinase IRAK-0_m-2.AA LISK-DD1 777-800 33 2.3e-05 15.64 In-house 267-290 (290) Show / Hide 
Range on Protein: 777-800
Range on HMM: 267-290/290
Sequence Identity: 33% (8 aa)

KLALECTKVSGKERPSMSHVAKTL
.|...|.|.  ..||| ...  ||
DLCMWCCKYDPNNRPSFKEIVQTL
Kinase IRAK-0_m-2.AA TK 707-732 43 2.8e-05 12.81 In-house 363-394 (486) Show / Hide 
Range on Protein: 707-732
Range on HMM: 363-394/486
Sequence Identity: 43% (14 aa)

SSQ-----LTTTSDVYSFGVVLLELMS-GQKP
|..      || |||.||||.. |... ||.|
SEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase IRAK-0_m-2.AA Pkinase_Tyr 711-732 52 0.000128 16.27 Pfam 192-214 (270) Show / Hide 
Range on Protein: 711-732
Range on HMM: 192-214/270
Sequence Identity: 52% (12 aa)

TTTSDVYSFGVVLLELMS-GQKP
|| |||.||||.. |... |..|
TTKSDVWSFGVLMWEIFTYGEQP
Kinase IRAK-0_m-2.AA LISK 776-800 32 0.000136 10.62 In-house 272-296 (296) Show / Hide 
Range on Protein: 776-800
Range on HMM: 272-296/296
Sequence Identity: 32% (8 aa)

VKLALECTKVSGKERPSMSHVAKTL
..|...|.|.  |.||| ... ..|
LDLCFDCCKYDPKNRPSFKEIVQWL
Kinase IRAK-0_m-2.AA LRRK 788-802 40 0.045302 3.1 In-house 337-351 (351) Show / Hide 
Range on Protein: 788-802
Range on HMM: 337-351/351
Sequence Identity: 40% (6 aa)

KERPSMSHVAKTLEE
|.||..| . |.|..
KKRPHFSQIVKRLSQ
Kinase IRAK-0_m-2.AA TK 778-800 26 0.070248 1.22 In-house 464-486 (486) Show / Hide 
Range on Protein: 778-800
Range on HMM: 464-486/486
Sequence Identity: 26% (6 aa)

LALECTKVSGKERPSMSHVAKTL
| ..| .   ..||..| . . |
LMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-0_m-2.AA Dicty4 788-802 29 0.146771 1.17 In-house 261-277 (277) Show / Hide 
Range on Protein: 788-802
Range on HMM: 261-277/277
Sequence Identity: 29% (5 aa)

KERPSMSHVAKT--LEE
. |||.. . .   ||.
QHRPSFEEIIQRRILEH
Kinase IRAK-0_m-2.AA MLK 788-800 30 0.196948 0.89 In-house 279-291 (291) Show / Hide 
Range on Protein: 788-800
Range on HMM: 279-291/291
Sequence Identity: 30% (4 aa)

KERPSMSHVAKTL
..|||.... . |
HKRPSFRQIVQHL