Gene IRAK-14_d-2 (S.moellendorffii)

IRAK-14_d-2

Species: S.moellendorffii
Alias: IRAK-14_d-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-14

Sequence

Name Sequence Type Origin Length Description Download
IRAK-14_d-2.AA Protein None 396 None Fasta, JSON
IRAK-14_d-2.NA RNA None 1191 None Fasta, JSON
IRAK-14_d-2.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of IRAK-14_d-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-14_d-2.AA IRAK 87-289 42 2.3e-79 269.97 In-house 7-230 (317) Show / Hide 
Range on Protein: 87-289
Range on HMM: 7-230/317
Sequence Identity: 42% (95 aa)

IGEGGFGTVFYGTLSGQA--VAVK----ARSSSSIQGTREFNT---ELNLLSRIQHENLVPLLGFCAEDEQEILIYPYMPNGSLQDRLYGEGFKRKP--L
|||||||.|. | .....  .|||     ...| ..  ..|..   || ...|..|.|.|||.|.|.| ..  |.|||||||||.||| . .    |  |
IGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPL

DWPTRLSIALGAAKGLSFLHAGG-DLSIIHRDIKSSNILLDQSMTAKVADFGFSKF---APQDGDSVV----SLEVRGTAGYLDPEYYL--TQELTVKSD
 |..|.||..|.|.|. |||  .   .|||.||||.|||||| .|.| .|||   |   |.   ....       ||||. |. ||.    . .||.|.|
SWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLTKKTD

VYSFGVVLLEVICGREPLSIDRPR
|||||.|||||. |. .   |||.
VYSFGIVLLEVLTGCRAVYDDRPE
Kinase IRAK-14_d-2.AA TKL 87-352 21 2.2e-62 213.6 In-house 1-364 (364) Show / Hide 
Range on Protein: 87-352
Range on HMM: 1-364/364
Sequence Identity: 21% (83 aa)

IGEGGFGTVFYGTLSG----------QAVAVKARSSSSIQGT---------------------------REFNTELNLLSRIQHENLVPLLGFCAEDEQE
||.||||.|. |.. |          . ||||  .| . . .                            ... |....||..|.|.|...|.| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------------ILIYPYMPNGSLQDRLYGEGFKRKPLDWPTRLSIALGAAKGLSFLHA-----GGDLS--IIHRDIKSSNILLDQSMT----------
              ... |.|.||| ..|           |. |...||..|.|...||.     ..     |||||.||.|||.|. .|          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT--KPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----AKVADFGFSKFAPQDGDSV-----------------VSLEVRGTAGYLDPEYYLTQ----------------ELTVKSDVYSFGVVLLEVICGREP
    .|..|||.|.|  |.|..                   .  ..|| ... ||    |                | . |.||||||.|| |......|
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

LS-ID-RPRS---------EWSLVEWARPYIQDTNIEAIVDSSISSSYSPEAMWRVLEVAMLSVQPHSSRRPSMSDIVREL
 . .. .|.          ..  ..  || | ..  .         .  | .. .. . ..   ..  . |||...|. .|
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH---K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-14_d-2.AA MLK 81-282 27 7.5e-39 132.44 In-house 1-235 (291) Show / Hide 
Range on Protein: 81-282
Range on HMM: 1-235/291
Sequence Identity: 27% (66 aa)

NCYKTMIGEGGFGTVFYGTLSGQA-----VAVKARS----SSSIQG--TREFNTELNLLSRIQHEN----LVPLLGFCAEDEQE-ILIYPYMPNGSLQDR
   .. ||.|.|| |. |.  ..      ||||.      ..|. .   ..|..| ..|....|.|     ....| |......  ..  |...||| . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LYGEGFKRK----------PLDWPTRLSIALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQ------SMTAKVADFGFSKFAPQDGDS-VVSLEVRGTA
|.|.  |              |    ...||  |.|...||.     |||||.||.|||.|.       .|.|..||| |..  | . .   |   .||.
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSN--AGTY

GYLDPEYY---LTQELTVKSDVYSFGVVLLEVICGREP
 .  ||       .  . |.||.|.|||| |.. ...|
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAK-14_d-2.AA TKL-Unique 83-275 31 1.3e-38 133.87 In-house 1-220 (290) Show / Hide 
Range on Protein: 83-275
Range on HMM: 1-220/290
Sequence Identity: 31% (69 aa)

YKTMIGEGGFGTVFYGTLSGQAVAVKARSS---SSIQGTREFNTELNLLSRIQ-HENLVPLLGFCA----EDEQEILIYPYMPNGSLQDRLY------GE
    |||||.|.|. |.  |  ||.|  .    || . ..||. |.|...... |.|.| . |.|.       . ...  |.| ||| | |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

GFKRKPLDWPTRLSIALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQS-----MTAKVADFGFSKFAPQDGDSVVS-------LEVRGTAGYLDPEYYL
  . ..|..  |...|. .|.|. .||  .   |||||.||||.|.|.      . .|..|||.|||. .. .. ..        .. |.. .. ||   
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

T--QELTVKSDVYSFGVVLLE
      . ||||||||.|| |
MNFCQYSEKSDVYSFGIVLWE
Kinase IRAK-14_d-2.AA Pkinase 87-291 24 2.2e-38 136.78 Pfam 7-223 (293) Show / Hide 
Range on Protein: 87-291
Range on HMM: 7-223/293
Sequence Identity: 24% (55 aa)

IGEGGFGTVFYGTLSGQA--VAVKARSSSSIQGTRE---FN-TELNLLSRIQHENLVPLLGFCAEDEQEILIYPYMPNG----SLQDRLYGEGFKRKPL-
||.|.||.|. ..  |    ||||  . ...    .   .. .|. .. |..|.| | |.... ..    .. .|...|    .| |.. .   ..... 
IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--WRHGCFY

-DWPTRLSIALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQSMTA----KVADFGFSKFAPQDGDSVVSLEVRGTAGYLDPEYYL-TQELTVKSDVYSF
 .. .  ....  ..|| ..|.    .|||||.|..|||.|. ..     |..|||..|..     ..    . || .|. ||  .  |. . |.|..|.
FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLLEVICGREPLSID----RPRSE
|..| |..||| | . .    . ...
GCILYEMLCGRPPFPGHCWHDN-HDQ
Kinase IRAK-14_d-2.AA LISK 86-291 28 5.3e-36 114.31 In-house 1-247 (296) Show / Hide 
Range on Protein: 86-291
Range on HMM: 1-247/296
Sequence Identity: 28% (70 aa)

MIGEGGFGTVFYGTLS--GQAVAVKARSS-----SSIQGTREFNTELNLLSRIQHENLVPLLGFCAE-DEQEILIYPYMPNGSLQDRLYGEGFKRKPLDW
 ||.|.|| |. ||.   || .|.|  ..          .. .. |. .. ...| | |   | | . | |  ..  |.  | |...|  .... .|| |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

PTRLSIALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQS----MTAKVADFGFSKFAPQDGDSV--------------------------------VSL
| |..|||. |.|.|.||. .   ||||| || |.|....     ..||.|||| . . .. .|                                  ..
PQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

EVRGTAGYLDPEYYLTQELTVKSDVYSFGVVLLEVICGREPLSIDRPRSE
 . ||.    ||  | |. . ..||.|||.||.| |.....   ..||..
TICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTP
Kinase IRAK-14_d-2.AA Dicty4 87-282 34 5e-35 114.38 In-house 7-216 (277) Show / Hide 
Range on Protein: 87-282
Range on HMM: 7-216/277
Sequence Identity: 34% (72 aa)

IGEGGFGTVFYGTLSGQAVAVKAR----SSSSIQGTREFNTELNLLSRIQHENLVPLLGFCA----EDEQEILIYPYMPNGSLQDRLYG---EGFKRKPL
||.|.||.|. ||  |..||||        ..     ||  | .... |.| |.. ..| |     . .       ||| |.|   |     |  ....|
IGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKL

DWPTRLS---IALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQSMTAKVADFGFSKFAPQDGDSVV-SLEVRGTAGYLDPEYYLTQELTVKSDVYSFGV
|||....   .|. ||.|.  ||.  .  |||||.||.|.| |.....||.|||.|.    . |       . ||...  ||    |. . |.|||||| 
DWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGI

VLLEVICGREP
|| |   . ||
VLWEILTRQEP
Kinase IRAK-14_d-2.AA RIPK 87-282 28 4.5e-34 113.48 In-house 1-227 (290) Show / Hide 
Range on Protein: 87-282
Range on HMM: 1-227/290
Sequence Identity: 28% (66 aa)

IGEGGFGTVFYGT--LSGQAVAVKARSSSSIQGT------REFNTELNLLSRIQHENLVPLLGFCAEDEQ------EILIYPYMPNGSLQDRLYGEG-FK
.| ||||.||  .    |  ||.|.  .  .. .       .   |   . ....|. ||..||| . |.        .   ||.|||| . |  .  . 
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

RKPLDWPTRLSIALGAAKGLSFLHAGGDLS--IIHRDIKSSNILLDQSMTAKVADFGFSKFAPQD--GD---------SVVSLEVRGTAGYLDPEYYLTQ
 .|. || |  .    . |  .||   .    ||||| | .|||.|  . .|.|||| ...  .   ..         |  |..  ||  |..|| ..| 
HHPDPWPLRCRMIHEISCGMCYLH---SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTD

ELTV------KSDVYSFGVVLLEVICGREP
.         |.|||||..|. ||  ...|
NKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase IRAK-14_d-2.AA TK 81-282 16 1.7e-33 109.04 In-house 1-394 (486) Show / Hide 
Range on Protein: 81-282
Range on HMM: 1-394/486
Sequence Identity: 16% (64 aa)

NCYKTMIGEGGFG---TVFYGTLSG---------------------------QAVAVKARSSSSIQGTREFNT-----------------ELNLLS--RI
  .   .||| ||   .|. |.. |                           . ||||   . . .  .||                   |. ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHENLVPLLGFCAED------------EQEILIYPYMPNGS----LQDRLY--GEGFKRKP---------------------------------------
.|.|.| |.| | ..            |  ...  |||.|.    |.| |    ..|.  .                                       
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWPTRLSIALGAAKGLSFLHAGGD---LSIIHRDIKSSNILLDQSMT-----------AKVADFG---
                               |. ...| ... .|.|...||. .      ..|||.   |.|......           .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FSKFAPQDGDSVVSLEVRGT-------------------AG-----YLDPEYYLTQE---------LTVKSDVYSFGVVLLEVIC-GREP
      ..  ..|.| ... . ...                    |     .. ||  ....          | ||||.||||.. |.   |.||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Pkinase_Tyr IRAK-14_d-2.AA Pkinase_Tyr 71-226 27 1.3e-31 107.65 Pfam 1-156 (270) Show / Hide 
Range on Protein: 71-226
Range on HMM: 1-156/270
Sequence Identity: 27% (46 aa)

LTLKEVVNATNCYKTMIGEGGFGTVFYGTLS------GQAVAVKARSSSSIQG---TREFNTELNLLSRI-QHENLVPLLGFCA-EDEQ--EILIYPYMP
.|. ..          .||| ||.|. ||.       .. ||||    .. .     ..|  |..... . .|.|.| |.| |  ..|.   ... .|||
ITFGKK----------LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMP

NGSLQDRLYGEGFKRKPLDWPTRLSIALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQSMTAKVADFG
.|.| | |      ..||. .. |....  |||...|.. .   .||||.   |.|.. ....|..|||
HGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFG
Kinase IRAK-14_d-2.AA Dicty5 82-282 30 4.9e-31 104.05 In-house 2-202 (260) Show / Hide 
Range on Protein: 82-282
Range on HMM: 2-202/260
Sequence Identity: 30% (65 aa)

CYKTMIGEGGFGTVFYGTLSGQAVAVKARSSSS--IQGTREFNTELNLLSRIQ--HENLVPLLGFCAEDEQE-ILIYPYMPNGSLQDRLYGEGFKRK---
    .|  |  |.|. |   |  ||.|  |.         ||  |  ..| .|  | |..  .|    ..     .  |  |||| . |     .||   
SFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLND---QRKTTG

-PLDWPTRLSIALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQSMTAKVADFGFSKFAPQDGDSVVSLEVRGTAGYLDPEYYLTQELTVKSDVYSFGVV
 |. ....|..|...|... .||     .|||||.|| |.|.    ..|. ||| | |   |      ..| ||  .  .| .  |  . | ||||||.|
QPIAYFQQLHMAIDIAQSMRHLHS---MNIIHRDLKSMNFLITENWKIKIIDFGTSRFV--DNRYHMTMHV-GTQCWMACELFNGQPYHQKCDVYSFGIV

LLEVICGREP
| |..   ||
LWEMFTRKEP
Kinase IRAK-14_d-2.AA DRK 87-277 36 6.3e-30 98.56 In-house 7-196 (258) Show / Hide 
Range on Protein: 87-277
Range on HMM: 7-196/258
Sequence Identity: 36% (71 aa)

IGEGGFGTVFYGTLSGQAVAVKARSSSSIQ---GTREFNTELNLLSRIQHENLVPLLGFCAEDEQEILIYPYMPNGSLQDRLYGEGFKRKPLDWPTRLSI
|| |..| || ||  |  ||||      |       ||  | ||...  | | .  .| | .      .  ||| |||   |  |  .   .||| ....
IGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIE---MDWPLMKQM

ALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQSMTAKVADFGFSKFAPQDGDSVVSLEVRGTAGYLDPEYYLTQELTVKSDVYSFGVVLLEVI
.. .|||. .|| . .  ||||| || | | | .   |||||| |    .  .        || .   ||    |  | | |||||..|| |..
MFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase IRAK-14_d-2.AA TyrKc 81-352 24 1.1e-27 99.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 81-352
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

NCYKTMIGEGGFGTVFYGTLSGQAVAVKARSSSSIQGTREFNTELNLLSRI--QHENLVPLLGFCAED-------EQEILIYPYMPNGSLQDRL-YGEGF
   . ..||| ||.|. ||.. . ||||   ...    ..|  |.......  .|.|.| |.| | ..       |.  ..  |||.|.|.|.| . .. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

KRKPLDWPTRLSIALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQSMTAKVADFGFSKFAPQD------GDSVVSLE---VR--GTAGYLDPEYYLTQE
    | ... ||... .|.| ..||      .||||.   |.|..   |.|..||| |..   |      .|  .. |    .       . ||   . .
----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LTVKSDVYSFGVVLLEVICGREPLSIDRPRSE-----WSLVEWARPYIQDTNIEAIVDS-----SISSSYSPEAMWRVLEVAMLSV-QPHSSRRPSMSDI
 | ||||.||||.. |.         . | ..      |  | .. |... .   . ..     .      |..| ..    |..  .   . ||..|.|
FTTKSDVWSFGVCMWEIFTY-----GQQPYPGMIQQMMSNQE-VIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQI----MKQCWHEDPEDRPTFSEI

VREL
....
HECF
Kinase IRAK-14_d-2.AA S_TKc 81-357 20 1.6e-23 85.42 SMART 1-231 (231) Show / Hide 
Range on Protein: 81-357
Range on HMM: 1-231/231
Sequence Identity: 20% (58 aa)

NCYKTMIGEGGFGTVFYGTL--SGQAVAVKARSSSSIQGTREFNTELNLLSRIQHENLVPLLGFCAEDEQEILIYPYMPN--GSLQDRLYGEGF--KRKP
      ||.|.||.|. ..   .|. ||.|  .       . .  |...|.. .|.|.| |.... . .   ..  |...  |.| |..   |   .|.|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWPTRLSIALGAAKGLSFLHAGGDLSIIHRDIKSSNILLDQSMTAKVADFGFSKFAPQDGDSVVSLEVRGTAGYLDPEYYLTQELTV-KSDVYSFGVVL
..  .  ...   ...| ..|   .. |||||.| .|||||.  . |..|||....            . ||  |. ||       .  |.|..|.|..|
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LEVICGREPLSIDRPRSEWSLVEWARPYIQDTNIEAIVDSSISSSYSPEAMWRVLEVAMLSVQPHSSRRPSMSDIVR----ELEDALI
 | .||. | .      .  . .  .                     .. ..  .   .| . |  ..||.  .. .       .  .
YEMLCGYPPFP-----QMQMMFKKIG---------------------SPEAKD-FIRKCLQKDP--EKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-14_d-2.AA Pkinase_Tyr 261-282 52 0.000384 14.65 Pfam 192-214 (270) Show / Hide 
Range on Protein: 261-282
Range on HMM: 192-214/270
Sequence Identity: 52% (12 aa)

TVKSDVYSFGVVLLEVIC-GREP
|.||||.||||.. |..  |..|
TTKSDVWSFGVLMWEIFTYGEQP
Kinase IRAK-14_d-2.AA Dicty4 340-354 35 0.002719 7.03 In-house 261-277 (277) Show / Hide 
Range on Protein: 340-354
Range on HMM: 261-277/277
Sequence Identity: 35% (6 aa)

SRRPSMSDIVRE--LED
..|||.. |. .  || 
QHRPSFEEIIQRRILEH
Kinase IRAK-14_d-2.AA TK 336-352 23 0.009789 4.14 In-house 470-486 (486) Show / Hide 
Range on Protein: 336-352
Range on HMM: 470-486/486
Sequence Identity: 23% (4 aa)

QPHSSRRPSMSDIVREL
..  ..||..|.....|
HYDPEDRPTFSQLHEQL
Kinase IRAK-14_d-2.AA MLK 336-352 35 0.011329 5.25 In-house 275-291 (291) Show / Hide 
Range on Protein: 336-352
Range on HMM: 275-291/291
Sequence Identity: 35% (6 aa)

QPHSSRRPSMSDIVREL
.. ...|||.. || .|
NQDPHKRPSFRQIVQHL
Kinase IRAK-14_d-2.AA DRK 340-354 40 0.024107 3.79 In-house 244-258 (258) Show / Hide 
Range on Protein: 340-354
Range on HMM: 244-258/258
Sequence Identity: 40% (6 aa)

SRRPSMSDIVRELED
. |||| ...  || 
QHRPSMQECLERLEA
Kinase IRAK-14_d-2.AA TKL-Unique 339-352 42 0.078098 2.47 In-house 277-290 (290) Show / Hide 
Range on Protein: 339-352
Range on HMM: 277-290/290
Sequence Identity: 42% (6 aa)

SSRRPSMSDIVREL
.| ||| ..|. .|
PSQRPSFDEIIHRL
Kinase IRAK-14_d-2.AA Pkinase_Tyr 336-352 29 0.148398 5.89 Pfam 254-270 (270) Show / Hide 
Range on Protein: 336-352
Range on HMM: 254-270/270
Sequence Identity: 29% (5 aa)

QPHSSRRPSMSDIVREL
..  ..||..|.|...|
HYDPEDRPTFSEIHEQL