Gene IRAK-14_a-1 (S.moellendorffii)

IRAK-14_a-1

Species: S.moellendorffii
Alias: IRAK-14_a-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-14

Sequence

Name Sequence Type Origin Length Description Download
IRAK-14_a-1.AA Protein None 852 None Fasta, JSON
IRAK-14_a-1.NA RNA None 2559 None Fasta, JSON
IRAK-14_a-1.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of IRAK-14_a-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Malectin IRAK-14_a-1.AA Malectin 29-50 20 8.055749 1.67 Pfam 1-24 (202) Show / Hide 
Range on Protein: 29-50
Range on HMM: 1-24/202
Sequence Identity: 20% (5 aa)

DFYRIDCGAASN--TSSGDRHWQG
  ..|.||.     |.|. .....
YSWHINCGGPEHYTTDSDGITYEA
Malectin IRAK-14_a-1.AA Malectin 311-358 26 2e-06 26.66 Pfam 107-162 (202) Show / Hide 
Range on Protein: 311-358
Range on HMM: 107-162/202
Sequence Identity: 26% (15 aa)

VRLHFAELYYTK-------TYQRMFNVYINNRTAIDGLDLIVLG-PRFTPVYKDFV
|.|||||.|..          .| |.|||.  . .. .|       ......| |.
VILHFAEIYFQDTDQTWNSPGRRVFDVYIQGKLVLKDFDIWKEAGGKGKAAHKEFI
Kinase IRAK-14_a-1.AA IRAK 513-708 38 1e-73 251.24 In-house 1-218 (317) Show / Hide 
Range on Protein: 513-708
Range on HMM: 1-218/317
Sequence Identity: 38% (84 aa)

FDNDLLLGVGGFGKVYKGEINGGT-KVAVK--RGNPMSEQG--MTEFQT---EIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMANGPLRGHLYGSD-A
|. |...| |||| ||.|.... |  .|||  . . .....  . .||.   |.. ....|| ..|.| ||| |...  |||.||.|| |.  | . | .
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

PT---LSWKQRLEICIGAARGLHYLHTGA-QRAIIHRDVKTTNILLDEKFVAKVSDFGLSKVG---PSLDHTHV----STAVKGSFGYLDPEYFR--RQQ
 .   ||| ||..||.|.|.|...||.     .|||.|.|. |||||. |..| .||||   |   ... .. .       |.|.  |. ||. |    |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTEKSDVYSFGVVLMEVV
|| |.||||||.||.||.
LTKKTDVYSFGIVLLEVL
Kinase IRAK-14_a-1.AA TKL 519-783 23 2.1e-62 213.61 In-house 1-364 (364) Show / Hide 
Range on Protein: 519-783
Range on HMM: 1-364/364
Sequence Identity: 23% (87 aa)

LGVGGFGKVYKGEING---------GTKVAVKRGNP---------------------------MSEQGMTEFQTEIEMLSKLRHRHLVSLIGYCDENSE-
.| ||||.||||. .|         |. ||||. .                            .... . ..  || |.|.||| ..|...||| ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------MILVYDYMANGPLRGHLYGSDAPTLSWKQRLEICIGAARGLHYLHT-----GAQRAIIHRDVKTTNILLDEKFV--------------
            . .|..|. .| |. .|         | ||. .....|||..|||.     .  ..||||| |. |||.||..               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AKVSDFGLSK-VGPSLDHTHVSTA----------------VKGSFGYLDPEYFRRQ----------------QLTEKSDVYSFGVVLMEVVCARPAINPA
.|..|||||. . .| . .. .|.                . |..... || .| |                . .||.||||||.|| |... ..   | 
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---PY

--LPRDQVSIA---EWALHWQKLGRLSNIMDPRLAG----DCTPESLQKFGEIAERCLADRGSERPSIGDVLWNL
  .| ... ..   |. . .  . .|   ..|.        . |  .. . .....| .   ..|||  ..|  |
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-14_a-1.AA TKL-Unique 518-708 33 6.9e-46 158.76 In-house 4-222 (290) Show / Hide 
Range on Protein: 518-708
Range on HMM: 4-222/290
Sequence Identity: 33% (75 aa)

LLGVGGFGKVYKGEINGGTKVAVKRGNP---MSEQGMTEFQTEIEMLSKLR-HRHLVSLIGYCD----ENSEMILVYDYMANGPLRGHLYG--------S
..| ||.|.||||. . |..||.|. .|    | . | ||  |.  ..||. |  .| ..|||      ...|..| .|.  | |. .|          .
KIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

DAPTLSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEK-----FVAKVSDFGLSKVGPSLDHTHVS-------TAVKGSFGYLDPEYFRR-
.  .|...||. . | .|.|..|||.     ||||| |..|.|.|..     . .|..||||||.  . . . ..       . ..||| .. || .|. 
NNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMN

-QQLTEKSDVYSFGVVLMEVV
  | .|||||||||.|| | .
FCQYSEKSDVYSFGIVLWEIA
Kinase IRAK-14_a-1.AA Dicty4 513-706 33 3.6e-40 131.79 In-house 1-209 (277) Show / Hide 
Range on Protein: 513-706
Range on HMM: 1-209/277
Sequence Identity: 33% (71 aa)

FDNDLLLGVGGFGKVYKGEINGGTKVAVKRG---NP-MSEQGMTEFQTEIEMLSKLRHRHLVSLIGYCD----ENSEMILVYDYMANGPLRGHLYGS---
 . . ..| |.||.||||    |..||||     |   .|  ..||  |.. ..|.|| ... . |.|     . ..|  |  ||  | |   |  .   
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLY-SLLHDKPS

---DAPTLSWKQRLE---ICIGAARGLHYLHTGAQRA--IIHRDVKTTNILLDEKFVAKVSDFGLSK-VGPSLDHTHVSTAVKGSFGYLDPEYFRRQQLT
   .  .|.|  ..    ... ||||. .||.   .   ||||| |. |.| |. ...||.|||||.   .  ||.   ....|. ..  ||  . |  .
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC---CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

EKSDVYSFGVVLME
||.|||||| || |
EKADVYSFGIVLWE
Kinase IRAK-14_a-1.AA Pkinase_Tyr 513-708 31 1.9e-39 134.19 Pfam 1-208 (270) Show / Hide 
Range on Protein: 513-708
Range on HMM: 1-208/270
Sequence Identity: 31% (66 aa)

FDNDLLLGVGGFGKVYKGEIN-----GGTKVAVKRG--NPMSEQ-GMTEFQTEIEMLSKL-RHRHLVSLIGYCD-ENSE--MILVYDYMANGPLRGHLYG
   .  || | ||.||||. .     ....||||    . |.||  . .|  |......| .| ..|.|.| |  .     ...|  ||..| |. .|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

S--DAPTLSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVAKVSDFGLSKVGPSLDHT-HVSTAVKGSFGYLDPEYFRRQQLTEKSDV
   | . |. |. |..|.  |.|. ||.   .. .||||. . |.|..|..|.|..||||..   . |   ....  |     . || ..    |.||||
HREDKQPLTMKDLLQMCWQIAKGMEYLE---SKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

YSFGVVLMEVV
.||||.. |..
WSFGVLMWEIF
Kinase IRAK-14_a-1.AA Pkinase 513-712 28 5.9e-39 138.81 Pfam 1-210 (293) Show / Hide 
Range on Protein: 513-712
Range on HMM: 1-210/293
Sequence Identity: 28% (62 aa)

FDNDLLLGVGGFGKVYKG-EINGGTKVAVKRGNPMSEQGMTEFQT-----EIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMANG----PLRGHLYGSD
.     .| |.||.|||. ... | .||||. .   .. . . ||     ||... .|.| . | |.... ..... .| .|. .|     |  .. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

APTL--SWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVA----KVSDFGLSKVGPSLDHTHVSTAVKGSFGYLDPEYFR-RQQLTEKS
  ..  |...   ..   .||| |.|   .. |||||.|  |||.|.. .     |..||||.|.   . . .  | . |. .|. ||  | .|  . |.
HGCFYFSEWECKFYMYQILRGLEYCH---SMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGVVLMEVVCARP
|..|.|..| |..| ||
DMWSCGCILYEMLCGRP
Kinase IRAK-14_a-1.AA MLK 513-708 27 8e-39 132.33 In-house 1-230 (291) Show / Hide 
Range on Protein: 513-708
Range on HMM: 1-230/291
Sequence Identity: 27% (64 aa)

FDNDLLLGVGGFGKVYKGEINGGT----KVAVKRGNPMSEQGMTE-------FQTEIEMLSKLRHRH----LVSLIGYCDEN-SEMILVYDYMANGPLRG
...   .|.|.||||.||.  . .     ||||| . . .  . .       |..|.. |..|.|.      . . | | .. ..  .|  |...|.|  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLYG-SDAPT-----------LSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDE------KFVAKVSDFGLSKVGPSLDHTHVS--TAVKG
 |.| .. .             .  . . ..   |||.||||  |. .||||| |  |||.||      . ..|..|||.|.   .. ... .  .  .|
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR---DWHQMC-TNMMSNAG

SFGYLDPEYF---RRQQLTEKSDVYSFGVVLMEVV
.. .  || .   | .. .||.||.|.|||| |..
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEML
Kinase IRAK-14_a-1.AA TK 513-708 16 8.8e-39 127.12 In-house 1-388 (486) Show / Hide 
Range on Protein: 513-708
Range on HMM: 1-388/486
Sequence Identity: 16% (66 aa)

FDNDLLLGVGGFG---KVYKGEINGG--------------------------TKVAVKRGN---PMSEQGMTE--------------FQTEIEMLS--KL
      || | ||   .||||| .|.                          |.||||      .||.. . .              .  |..|..  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHRHLVSLIGYCDEN------------SEMILVYDYMANGP----LRGHLYGSDAP--------------------------------------------
.| ..|.|.|.| ..              ...|  ||..|     || .|  .. .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------TLSWKQRLEICIGAARGLHYLHTGAQR-----AIIHRDVKTTNILLDEKFV-----------AKVSDFGL
                              .|. .|.| .|  .|.|. |||  ...      ..|||. . |.|..|. |           .|..||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLH--SKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL

SK-----VGPSLDHTHVSTAVKGSFG---------------------------YLDPEYFRRQQ---------LTEKSDVYSFGVVLMEVV
|.         ... .  .....  .                           .. || .. ..          |.||||.||||.. |..
SRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIF
Kinase IRAK-14_a-1.AA TyrKc 513-783 24 5.1e-36 126.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 513-783
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

FDNDLLLGVGGFGKVYKGEINGGTKVAVKRGNPMSEQGMTEFQTEIEMLSKL--RHRHLVSLIGYCDEN-------SEMILVYDYMANGPLRGHLYGSDA
   .  || | ||.||||. .  ..||||  .. .   . .|  |.....||  .| ..| |.|.| .          . .|  ||..| |. .|  .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

PTLSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVAKVSDFGLSKVGPSL-------DHTHVST--AVK--GSFGYLDPEYFRRQQLT
  |..|. |..|. .|.|  |||      .||||  . |.|..|....|.||||||. . .        |  ....    |       . || ..    |
K-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKSDVYSFGVVLMEVV--CARPAINPAL-PRDQVSIAEWALHWQKLGRLSNIMDPRLAGDCTPESLQKFGEIAERCLADRGSERPSIGDVLWNL
.||||.||||.. |.   .. |  .... . .   . |.  .   . .  |.  | ..    ..  ..  .| ..| .   ..||.  ..   .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAK-14_a-1.AA DRK 520-708 34 1.3e-34 114.68 In-house 8-196 (258) Show / Hide 
Range on Protein: 520-708
Range on HMM: 8-196/258
Sequence Identity: 34% (67 aa)

GVGGFGKVYKGEINGGTKVAVKRGNPMSEQ---GMTEFQTEIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMANGPLRGHLYGSDAPTLSWKQRLEICI
| |..| |. |    ||.||||.     .     . ||. ||.....|||   .  .| | . ..   .  ||  | |   |   ..  ..|  .. . .
GRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH-DESIEMDWPLMKQMMF

GAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVAKVSDFGLSK-VGPSLDHTHVSTAVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLMEVV
 .|.|. ||| .    ||||| |. | | || .  ||.|||||      ..|.   |.. |  .   ||  | |  ||| |||||..|| |.|
DCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase IRAK-14_a-1.AA TK-Unique 513-709 23 6.1e-33 110.98 In-house 1-234 (294) Show / Hide 
Range on Protein: 513-709
Range on HMM: 1-234/294
Sequence Identity: 23% (57 aa)

FDNDLLLGVGGFGKVYKGEINGGT-------KVAVKRGN-PMSEQGMTEFQTEIEMLSKLR-HRHLVSLIGYCDENS-EMILVYDYMANGPLRGHLYGSD
. .. ..| | || |..||. |..       .||||  . . ...   .|  ||.|...|  | ..|...|.| ...  . ... |...| |...|  . 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

AP------------------------TLSWKQRLEICIGAARGLHYLHTGAQ--RAIIHRDVKTTNILLDEKFVAKVSDFGLSKVGPSLDHTHVSTA--V
 .                        ..| |. . .... |.|. ||   |.  . |.|||. . |.|| |..|.|..|||... .   .. ....    
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYL---ASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQG

KGSFGYLDPEYFR--RQQL-TEKSDVYSFGVVLMEVVC
. .  .. ||...  ...  |.||||.||||.. |...
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase IRAK-14_a-1.AA RIPK 519-707 30 1.9e-31 104.4 In-house 1-221 (290) Show / Hide 
Range on Protein: 519-707
Range on HMM: 1-221/290
Sequence Identity: 30% (68 aa)

LGVGGFGKVYKGE-INGGTKVAVKRGN------PMSEQGMTEFQTEIEMLSKLRHRHLVSLIGYCDEN-----SE-MILVYDYMANGPLRGHLYGSDA--
.| ||||.|.|      |. ||.|  .      .| .|  ..   | ... |||..| |.. | | .      .. . .|  ||.|| | . |       
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-PTLSWKQRLEICIGAARGLHYLHTGAQRA--IIHRDVKTTNILLDEKFVAKVSDFGLSKV-GPSLDHT--------HVSTAVK--GSFGYLDPEYFR--
 . . |. |  .    ..| .|||        ||||| |. |||.|  | .|..||||..  . |  |.          ..  .  |   |..|| ||  
HHPDPWPLRCRMIHEISCGMCYLH---SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTD

-RQQ---LTEKSDVYSFGVVLMEV
 .      |.|.|||||..|. ||
NKKPIKVVTPKYDVYSFAIVMWEV
Kinase IRAK-14_a-1.AA LRRK 513-704 25 2.2e-29 101.12 In-house 1-272 (351) Show / Hide 
Range on Protein: 513-704
Range on HMM: 1-272/351
Sequence Identity: 25% (72 aa)

FDNDLLLGVGGFG-KVYKGEING---------------------------GTKVAVKRGNP------------------------MSEQGM---------
.    ..|.|||| .||... .|                           ...||.|  |                         . |  |         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

--TEFQTEIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMANGPLRGHLY--GSDA-----PTLSWKQRLEICIGAARGLHYLHTGAQRA--IIHRDVKT
   ||. |. ..|.|.| ..|||.|.|   . ...| .|. .| |  .|    .|.     . .||  .|.| .  |.|. |||    .   ||||| |.
AFREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKS

TNILL---D---------EKFVAKVSDFGLSKVGPSLDHTHVSTAVKGSFGYLDPEYFR---RQQLTEKSDVYSFGVVL
 ||||   .         .  .||..|||.| .  . .|. |   . | .|.. ||  |   . . |||.|.||||..|
PNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase IRAK-14_a-1.AA S_TKc 513-786 21 4.9e-29 103.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 513-786
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

FDNDLLLGVGGFGKVYKGEING-GTKVAVKRGNPMSEQGMTEFQTEIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMAN--GPLRGHLYGSDAPT----
..   ..| |.||||||.  .. | .||.|. .         .. ||..|.| .| ..| |...... ... .| .|. .  | |. ..     .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVAKVSDFGLSKVGPSLDHTHVSTAVKGSFGYLDPEYFRRQQLTE-KSDVYSFGVVL
..  .   ..   ...| |.|   .. |||||.|  ||||||  . |..||||...          | . |.  |. || .   . .  |.|..|.|..|
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

MEVVCARPAINPALPRDQVSIAEWALHWQKLGRLSNIMDPRLAGDCTPESLQKFGEIAERCLADRGSERPSIGDVLW------NLEYS
 | .| .|        ..  . .  .                       | .    . ..||    ..||.. ..|       . .. 
YEMLCGYPPFP-----QMQMMFKKIG-----------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-14_a-1.AA IRAK 745-783 20 0.000767 9.69 In-house 279-317 (317) Show / Hide 
Range on Protein: 745-783
Range on HMM: 279-317/317
Sequence Identity: 20% (8 aa)

RLAGDCTPESLQKFGEIAERCLADRGSERPSIGDVLWNL
.....| |.. ...   | .|.. |  .|...  |.  |
HRMPPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAK-14_a-1.AA TK-Unique 763-783 28 0.303947 0.19 In-house 274-294 (294) Show / Hide 
Range on Protein: 763-783
Range on HMM: 274-294/294
Sequence Identity: 28% (6 aa)

ERCLADRGSERPSIGDVLWNL
..|. .  .||||. ...  |
KSCWQWEPEERPSFRQIKHRL