Gene IRAK-Un_ca (S.moellendorffii)

IRAK-Un_ca

Species: S.moellendorffii
Alias: IRAK-Un_ca
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_ca.AA Protein None 195 None Fasta, JSON
IRAK-Un_ca.NA RNA None 588 None Fasta, JSON
IRAK-Un_ca.kin_dom Protein Kinase Domain None 45 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_ca.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_ca.AA TKL-Unique 79-127 27 1.5e-10 33.57 In-house 113-165 (290) Show / Hide 
Range on Protein: 79-127
Range on HMM: 113-165/290
Sequence Identity: 27% (15 aa)

IQDSREIARGICFLHEECSTRVLHLAINPQNTLLAEN-----FGVKIADVGLSR
... . ||.| ..|| .  . ..|... ..|.|. .|     . .||.|.|||.
VKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSK
Kinase IRAK-Un_ca.AA TKL 82-146 18 4.5e-10 32.47 In-house 138-279 (364) Show / Hide 
Range on Protein: 82-146
Range on HMM: 138-279/364
Sequence Identity: 18% (26 aa)

SREIARGICFLHEECS-----TRVLHLAINPQNTLLAENFG--------------VKIADVGLSRW--------------------------RMMKV---
...||||...|| .         ..|  ....| |. ||.               .||.| ||||.                          .|...   
ALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTP

-----------------------------SDKLDVYSFALCW
                             | | |||||....
RWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL
Kinase IRAK-Un_ca.AA RIPK 84-131 44 1.1e-09 29.2 In-house 115-161 (290) Show / Hide 
Range on Protein: 84-131
Range on HMM: 115-161/290
Sequence Identity: 44% (22 aa)

EIARGICFLHEECSTR--VLHLAINPQNTLLAENFGVKIADVGLSRWRMM
||..| |.||   |    ..|.   |.| |.  || ||||| ||. |.|.
EISCGMCYLH---SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMW
Kinase IRAK-Un_ca.AA MSN 82-126 44 4.7e-07 19.09 In-house 110-151 (265) Show / Hide 
Range on Protein: 82-126
Range on HMM: 110-151/265
Sequence Identity: 44% (20 aa)

SREIARGICFLHEECSTRVLHLAINPQNTLLAENFGVKIADVGLS
.||| ||. .||..   .|.|  |  || || .|  ||. | | |
CREILRGLAHLHQH---KVIHRDIKGQNVLLTHNAEVKLVDFGVS
Kinase IRAK-Un_ca.AA MLK 82-127 28 2e-06 18.56 In-house 130-181 (291) Show / Hide 
Range on Protein: 82-127
Range on HMM: 130-181/291
Sequence Identity: 28% (15 aa)

SREIARGICFLHEECSTRVLHLAINPQNTLLAE------NFGVKIADVGLSR
.  .|||. .||..    . |  ....| |..|      .  .||.| |.||
ALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR
Kinase IRAK-Un_ca.AA CDK4 82-127 41 3e-06 17.45 In-house 116-158 (290) Show / Hide 
Range on Protein: 82-127
Range on HMM: 116-158/290
Sequence Identity: 41% (19 aa)

SREIARGICFLHEECSTRVLHLAINPQNTLLAENFGVKIADVGLSR
.... ||. |||   | |. |    ||| |.. .  ||.|| ||.|
MHQLLRGVDFLH---SHRIIHRDLKPQNILVTSDGHVKLADFGLAR
Kinase IRAK-Un_ca.AA Fused 97-127 45 2e-05 14.35 In-house 115-145 (251) Show / Hide 
Range on Protein: 97-127
Range on HMM: 115-145/251
Sequence Identity: 45% (14 aa)

STRVLHLAINPQNTLLAENFGVKIADVGLSR
| |.||  . ||| ||. | ..|  | |. |
SHRILHRDMKPQNILLDKNMHIKLCDFGFAR
Kinase IRAK-Un_ca.AA Dicty4 85-127 37 3.2e-05 13.56 In-house 121-162 (277) Show / Hide 
Range on Protein: 85-127
Range on HMM: 121-162/277
Sequence Identity: 37% (16 aa)

IARGICFLHEECSTRVLHLAINPQNTLLAENFGVKIADVGLSR
.|||.  ||. | ....|. . . | |  .|. ||..| |||.
AARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQ
Kinase IRAK-Un_ca.AA CDC2 85-127 39 3.9e-05 11.15 In-house 112-151 (301) Show / Hide 
Range on Protein: 85-127
Range on HMM: 112-151/301
Sequence Identity: 39% (17 aa)

IARGICFLHEECSTRVLHLAINPQNTLLAENFGVKIADVGLSR
| .|..|.|   . |..|  . ||| |. ..  .|||| ||.|
ILQGVHFCH---QRRIMHRDLKPQNILIDKKGNIKIADFGLAR
Kinase IRAK-Un_ca.AA Trio 88-124 29 5.8e-05 7.95 In-house 107-144 (258) Show / Hide 
Range on Protein: 88-124
Range on HMM: 107-144/258
Sequence Identity: 29% (12 aa)

GICFLHEECSTRVLHLAINPQNTLLAENFG----VKIADVG
... ||   . ..||| | | | ....  .    .||.| |
AVHYLH---NCHILHLDIKPENMMMWHYNAGRPQIKICDFG