Gene IRAK-Un_dg (S.moellendorffii)

IRAK-Un_dg

Species: S.moellendorffii
Alias: IRAK-Un_dg
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_dg.AA Protein None 368 None Fasta, JSON
IRAK-Un_dg.NA RNA None 1107 None Fasta, JSON
IRAK-Un_dg.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_dg.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_dg.AA TKL 85-221 23 5.7e-34 119.18 In-house 1-195 (364) Show / Hide 
Range on Protein: 85-221
Range on HMM: 1-195/364
Sequence Identity: 23% (48 aa)

IGQGSTNRVYKGILSD---------GMEVAVKKLKQDVS------------------------ECSDVEASFRFQMELLSRVHHQHLANLVGICDEKQE-
||.|.   ||||..           | .|||||.|.. .                        | |  .  ..... ..|| .|...  ..|.| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RMLLFQYAPNGTLFENLHTGDENLSWKQRMRIIVGAAYGLAYLHHLCN-----PPVIHGDLRSRNILLTEDFA--------------A
             ..  .|.|.|.|...||       | ||.|.. ..| |..|||         ||.|| || |.|||. |..               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KV
|.
KI
Kinase IRAK-Un_dg.AA IRAK 82-342 26 1.8e-32 112.41 In-house 4-317 (317) Show / Hide 
Range on Protein: 82-342
Range on HMM: 4-317/317
Sequence Identity: 26% (84 aa)

SNLIGQGSTNRVYKGILSDGME--VAVKKLKQDV-SECSDVEASFRF---QMELLSRVHHQHLANLVGICDEKQERMLLFQYAPNGTLFENLHTGDE--N
.|.||.|    ||.| . .. .  .||||||. . ...  .. .|.     .....| .| ..  | | | | |.  | ..| |||.|.  |.  |    
DNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCP

---LSWKQRMRIIVGAAYGLAYLHHLC-NPPVIHGDLRSRNILLTEDFAAKV--WAMVVP-------IAGSS---ELALVRKTGGYVDPEIVH--RGVYS
   ||| ||  |  |.| |. .|| .    |.||||  | |||| ..| .|    ... .        ....   .  .||.|  |  ||      | ..
PKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLT

RAGDVFSFGVLLLEVLSGK-QAFSE--ETGMLVEWAQQFLQSRD---------------------RMM----DLVDKSMSNVCPMELYSVCELARLCTQR
   ||.|||. |||||.|  .. ..  |.  |..  .   ...                      | |    ...|. |. . | .  . | .|  |. .
KKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQCACCCGHH

ESSSRPSMRDVSDLL
    |..|. |  .|
RANRRCDMAWVMQQL
Kinase IRAK-Un_dg.AA TKL-Unique 81-221 26 3.9e-24 82.11 In-house 1-158 (290) Show / Hide 
Range on Protein: 81-221
Range on HMM: 1-158/290
Sequence Identity: 26% (43 aa)

FSNLIGQGSTNRVYKGILSDGMEVAVKKLKQDVSECS-DVEASFRFQMELLSRVH-HQHLANLVGICD----EKQERMLLFQYAPNGTLFENLH------
|.|.||.|.  .||||.   | .||.|...   .. | ...  |. .  .... | |  .  ..|.|        .. .   | | |.| ..||      
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---TGDENLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTED-----FAAKV
       .|...||....  .| |. ||||.  | .||.||.|.|.|....     . .|.
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKI
Pkinase_Tyr IRAK-Un_dg.AA Pkinase_Tyr 74-221 23 4.5e-23 78.77 Pfam 1-152 (270) Show / Hide 
Range on Protein: 74-221
Range on HMM: 1-152/270
Sequence Identity: 23% (39 aa)

VELLSEGFSNLIGQGSTNRVYKGILS-----DGMEVAVKKLKQDVSECSDVE---ASFRFQMELLSRV-HHQHLANLVGICD-EKQE--RMLLFQYAPNG
.... .     .|.|.  .||||..      ....||||.||.    ... .   ..|   .....   ||... .|.|.|  ...    .. . |.|.|
ITFGKK-----LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG

TLFENLHTG---DENLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAKV
 | . |..    ...|. |.   . .  | |..||.       || ||. ||.|.||.. .|.
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKI
Kinase IRAK-Un_dg.AA TK 92-221 13 1.4e-21 68.45 In-house 17-292 (486) Show / Hide 
Range on Protein: 92-221
Range on HMM: 17-292/486
Sequence Identity: 13% (37 aa)

RVYKGILSDG--------------------------MEVAVKKLKQD-VSECSDVEA-------------SFRFQMELLS--RVHHQHLANLVGICDEK-
.||||.. ..                          ..|||| || .  ..  . ..             ..   |....    ||... .|.|.| .. 
EVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGE

-----------QERMLLFQYAPNGT----LFENLHTGDEN------------------------------------------------------------
           .  |..  |.|.|     | . |.. ...                                                            
PKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKD

---------------LSWKQRMRIIVGAAYGLAYLHHL----CNPPVIHGDLRSRNILLTEDFA-----------AKV
               |. .|.. . . .| |..||| .      . ..|.||  ||.|..|.             .|.
LLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKI
Kinase IRAK-Un_dg.AA MLK 79-221 22 9.4e-18 58.26 In-house 1-174 (291) Show / Hide 
Range on Protein: 79-221
Range on HMM: 1-174/291
Sequence Identity: 22% (39 aa)

EGFSNLIGQGSTNRVYKGILSDGME-----VAVKKLKQDVSECSDVE----ASFRFQMELLSRVHHQH----LANLVGICDEK-QERMLLFQYAPNGTLF
  |.  || ||   |.||    ...     ||||. ...   .. ..      |.   ..|... |.        ..|.| .  ..  .. .|...| |.
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

ENLHTGDE-------------NLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTE------DFAAKV
. ||...              . .  . |.. .  | |..||| .  .|.|| || |.|||..|      .  .|.
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKI
Kinase IRAK-Un_dg.AA LRRK 79-213 22 9.9e-18 59.29 In-house 1-199 (351) Show / Hide 
Range on Protein: 79-213
Range on HMM: 1-199/351
Sequence Identity: 22% (46 aa)

EGFSNLIGQGSTN-RVYKGILSD---------------------------GMEVAVKKLKQD-------------------------------VSECSDV
  . ..||.|... .||.... .                           . .||.||.. |                                ..|. .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EASFRFQMELLSRVHHQHLANLVGICDEKQERMLLFQYAPNGTLFENLH--TGDE------NLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNI
  .||  . ..|. .| .. .|.|.|   . ...   |||.|.| . ||    |.      ..||  . .| .  | |..|||  .|||.|| ||.| ||
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNI

LL
||
LL
Kinase IRAK-Un_dg.AA TKL-ciliate1 81-220 26 2e-17 56.2 In-house 3-145 (279) Show / Hide 
Range on Protein: 81-220
Range on HMM: 3-145/279
Sequence Identity: 26% (39 aa)

FSNLIGQGSTNRVYKGILSDGMEVAVKKLKQDVSEC--SDVEASFRFQMELLSRVHHQHLANLVGICDEKQERMLLFQYAPNGTLFENLHTGDE---NLS
. . || |.   ||||  .   .||..... . |.    .  . .|    .   . |  |  |.||   .    .   . . ||.|. .|        ..
MGQKIGSGHFCNVYKGRCNS-YDVAIMNMNYFNSQESFINQKEFQREIQQHIKIKQHINLQQLQGISFYDNNFYIIMEHCHKGTMFDICHRKHSQIYMIK

WKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAK
| .|||..   | |. ||| . ..| || || . |||. |..  |
WQHRMRWCKDIAQGMQYLHMR-QNPLIHRDLKMQNILYDEPYQYK
Kinase IRAK-Un_dg.AA TyrKc 79-342 22 6.4e-17 50.83 SMART 1-280 (280) Show / Hide 
Range on Protein: 79-342
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

EGFSNLIGQGSTNRVYKGILSDGMEVAVKKLKQDVSECSDVEASFRFQMELLSRV--HHQHLANLVGICDEK-------QERMLLFQYAPNGTLFENLHT
  .   .| |   .||||...  ..||||.|| |       .. |.  .......  ||... .|.|.| ..       .  |... |.|.| | . |. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

GDENLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAKV--WAMVVPIAGS-----SELALVRKTGGYVD---------PEIVHRGV
  ..|..|.   . . .| | .|||.    ..|| ||  ||.|..|.. .|.    .   |        |.   . |...  .         ||    |.
HRPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YSRAGDVFSFGVLLLEVLS-GKQAFSEETG--MLVEWAQQFLQSRDRMMDLVDKSMSNV-------CPMELYSVCELARLCTQRESSSRPSMRDVSDLL
.. . ||.||||.. |... |.|  ....   |  . . .......||.      . |.       || |.|   .. . | ... ..||..... ...
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMP-----QPPNDYPMSFVCCPDEMY---QIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAK-Un_dg.AA Dicty5 80-221 26 5.6e-16 51.49 In-house 2-145 (260) Show / Hide 
Range on Protein: 80-221
Range on HMM: 2-145/260
Sequence Identity: 26% (40 aa)

GFSNLIGQGSTNRVYKGILSDGMEVAVKKLKQDVSECSDVEASFRFQMELLSRVH--HQHLANLVGICDEKQER-MLLFQYAPNGTLFENLHTGDE----
 |   |  |.  |||.||   || ||.| . |..  | | . .|     ..| .   |  ..   |     .     .  |  ||.||. |         
SFHDWIASGASGRVYNGIY-KGMDVAIKVYSQENCMCFDWN-EFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQ

NLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAKV
.... |.. . ...| .. .||      .|| || | |.|.||.. .|.
PIAYFQQLHMAIDIAQSMRHLHSMN---IIHRDLKSMNFLITENWKIKI
Kinase IRAK-Un_dg.AA S_TKc 79-347 18 2.4e-14 33.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 79-347
Range on HMM: 1-231/231
Sequence Identity: 18% (52 aa)

EGFSNLIGQGSTNRVYKGILSD-GMEVAVKKLKQDVSECSDVEASFRFQME--LLSRVHHQHLANLVGICDEKQERMLLFQYAPN--GTLFENLHTGDEN
  . ..||.|.  .|||..  . | .||.|..|             ... |  .|.. || .. .| ..... ..  . . |...  |.||. ..    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAKV----WAMVVPIAGSSELALVRKTGGYVDPEIVHRGVYSR-AGDVFSF
     ..  .  ...   . .|.|.| .    .|| ||   ||||.|    |.     | ..          .  |  |. ||..    |.. . |. |.
GLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GVLLLEVLSGKQAFSEETGMLVEWAQQFLQSRDRMMDLVDKSMSNVCPMELYSVCELARLCTQRESSSRPSMRDVSD----LLVQSLA
|..| | |.|.  |.     . .  .. .                       ..... | | |.. . ||.  ..             
GCILYEMLCGYPPFP----QMQMMFKKIG---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-Un_dg.AA UTK 81-216 23 3.3e-14 45.03 In-house 3-154 (296) Show / Hide 
Range on Protein: 81-216
Range on HMM: 3-154/296
Sequence Identity: 23% (38 aa)

FSNLIGQGSTNRVYKGILSD------GMEVAVKKLKQDVSECSDVEASFRFQME-------------LLSRVH-HQHLANLVGICDEKQERMLLFQYAPN
.....|||    |.|. . .       | ||||...        ..|. ....|             .....| |.....|||.|   .  |..  |..|
LGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ--------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMEN

GTLFENLHTGDEN-------LSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTED
| |   | .  ..       |.  ||.   .  | |..|||      ..|.||  ||.|....
GDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG---FVHRDLAARNCLVHMH
Kinase IRAK-Un_dg.AA TK-Unique 81-221 22 4e-14 45.2 In-house 3-174 (294) Show / Hide 
Range on Protein: 81-221
Range on HMM: 3-174/294
Sequence Identity: 22% (40 aa)

FSNLIGQGSTNRVYKGILSDGM-------EVAVKKLKQDVSECSDVEASFRFQMELLSRVH-HQHLANLVGICDEKQ-ERMLLFQYAPNGTLFENLHTGD
. ..||.|.   |..| .. ..        ||||.|| .... .. .   ..||  .. .  |... ...|.| ...   |... |.|.|.|   |.|  
VGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQM--MKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

EN-------------------------LSWKQRMRIIVGAAYGLAYLHH-LCNPPVIHGDLRSRNILLTEDFAAKV
 .                         .| |.  ..... | |..||.  ...  ..|.|| .||.|||||. .|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK--IVHRDLCARNVLLTEDKVCKI
Kinase IRAK-Un_dg.AA TKL 245-342 20 7.8e-14 46.2 In-house 258-364 (364) Show / Hide 
Range on Protein: 245-342
Range on HMM: 258-364/364
Sequence Identity: 20% (23 aa)

DPEIVHRGVYSRAGDVFSFGVLLLEVLSGKQAFSEETGMLVEWA-----QQFLQSRDRMMDLVD-------KSMSNVCPMELYSVCELARLCTQRESSSR
|. . . . || . ||.|||..| |.|.... ....  | ....      . . . ...  ...       | |   ||  . |...|.  | . . ..|
DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHK-M-CPCPDCPPSMKKLMQDCWDHDPEKR

PSMRDVSDLL
||. .. . |
PSFQEILKRL
Kinase IRAK-Un_dg.AA Pkinase 85-221 22 6e-09 32.73 Pfam 7-153 (293) Show / Hide 
Range on Protein: 85-221
Range on HMM: 7-153/293
Sequence Identity: 22% (34 aa)

IGQGSTNRVYKGILSDGME-VAVKKLKQDVSECSDVEASFR-FQMELLSRVHHQHLANLVGICDEKQERMLLFQYAPNG----TLFENLH-TGDENL--S
||.||  .|||..  .  . ||||..| .  ...  .. .|    ... |..| .   | ... .|..  . . |...|     ||. ..   . ..  |
IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFS

WKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAA----KV
...  ...   . ||.|.|      .|| || . |||. ..       |.
EWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKI
Kinase IRAK-Un_dg.AA TK 246-342 17 7.1e-09 25.09 In-house 354-486 (486) Show / Hide 
Range on Protein: 246-342
Range on HMM: 354-486/486
Sequence Identity: 17% (23 aa)

PEIVH---------RGVYSRAGDVFSFGVLLLEVLS-GKQAFSEETGMLVEWA----QQFLQSRDRMMDL-----------VDKSMSNVCP---------
|| .           |... . ||.|||||. |... |.. . ..      |.    |....   |   |             .     ||         
PECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHP

--MELYSVCELARLCTQRESSSRPSMRDVSDLL
  ..   . .| . | ... . ||..... . |
PHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-Un_dg.AA UTK 246-273 31 7.6e-07 19.46 In-house 208-236 (296) Show / Hide 
Range on Protein: 246-273
Range on HMM: 208-236/296
Sequence Identity: 31% (9 aa)

PEIVHRG-VYSRAGDVFSFGVLLLEVLSG
||..  .  .... ||.||||.. |....
PEALTHHTRFTTKSDVWSFGVVCWEIWTW
Kinase IRAK-Un_dg.AA TK-Unique 246-272 40 4e-05 13.77 In-house 205-234 (294) Show / Hide 
Range on Protein: 246-272
Range on HMM: 205-234/294
Sequence Identity: 40% (12 aa)

PEIVH--RGVY-SRAGDVFSFGVLLLEVLS
||.    .|.| .  .|| |||||. |...
PESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_dg.AA LRRK 246-279 34 4.5e-05 13.87 In-house 248-285 (351) Show / Hide 
Range on Protein: 246-279
Range on HMM: 248-285/351
Sequence Identity: 34% (13 aa)

PEIVHRG---VYSRAGDVFSFGVLLLEVLSGK-QAFSE
|||.  .   .|.   |..|||..| | |... ..| |
PEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDE
Kinase IRAK-Un_dg.AA MLK 254-274 47 0.000191 11.48 In-house 213-233 (291) Show / Hide 
Range on Protein: 254-274
Range on HMM: 213-233/291
Sequence Identity: 47% (10 aa)

YSRAGDVFSFGVLLLEVLSGK
||.. ||.|.||.| |.|...
YSEKCDVWSWGVVLWEMLTRE
Kinase IRAK-Un_dg.AA Pkinase 246-280 30 0.001771 13.38 Pfam 180-215 (293) Show / Hide 
Range on Protein: 246-280
Range on HMM: 180-215/293
Sequence Identity: 30% (11 aa)

PEIVH-RGVYSRAGDVFSFGVLLLEVLSGKQAFSEE
||..  .  |... |..|.|..| |.|.|.  |...
PEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH
Kinase IRAK-Un_dg.AA TKL-Unique 246-275 37 0.002195 8.01 In-house 195-226 (290) Show / Hide 
Range on Protein: 246-275
Range on HMM: 195-226/290
Sequence Identity: 37% (12 aa)

PEIVHR--GVYSRAGDVFSFGVLLLEVLSGKQ
||.  .    ||.  ||.|||. | | ...|.
PEVLRMNFCQYSEKSDVYSFGIVLWEIATRKI
Kinase IRAK-Un_dg.AA Pkinase_Tyr 246-275 41 0.004757 10.95 Pfam 183-213 (270) Show / Hide 
Range on Protein: 246-275
Range on HMM: 183-213/270
Sequence Identity: 41% (13 aa)

PEIVHRGVYSRAGDVFSFGVLLLEVLS-GKQ
||  . |... . || |||||. |... |.|
PECINYGKFTTKSDVWSFGVLMWEIFTYGEQ
Kinase IRAK-Un_dg.AA TK-Unique 324-342 42 0.009695 5.42 In-house 276-294 (294) Show / Hide 
Range on Protein: 324-342
Range on HMM: 276-294/294
Sequence Identity: 42% (8 aa)

CTQRESSSRPSMRDVSDLL
|.|.| ..||| |.. . |
CWQWEPEERPSFRQIKHRL
Kinase IRAK-Un_dg.AA Dicty5 240-281 26 0.010581 5.12 In-house 166-207 (260) Show / Hide 
Range on Protein: 240-281
Range on HMM: 166-207/260
Sequence Identity: 26% (11 aa)

TGGYVDPEIVHRGVYSRAGDVFSFGVLLLEVLSGKQAFSEET
|  .  .|.     |    ||.|||. | |..  | .. . .
TQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNIN
Kinase IRAK-Un_dg.AA UTK 310-342 24 0.021283 4.02 In-house 267-296 (296) Show / Hide 
Range on Protein: 310-342
Range on HMM: 267-296/296
Sequence Identity: 24% (8 aa)

CPMELYSVCELARLCTQRESSSRPSMRDVSDLL
||...|   .| . | . . . ||...|. . .
CPHPVY---RLMHRCWHYDPQERPDFEDLVQQM
Kinase IRAK-Un_dg.AA LRRK 323-344 27 0.032035 3.64 In-house 330-351 (351) Show / Hide 
Range on Protein: 323-344
Range on HMM: 330-351/351
Sequence Identity: 27% (6 aa)

LCTQRESSSRPSMRDVSDLLVQ
.| | .  .||.. .. . | |
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAK-Un_dg.AA Pkinase_Tyr 310-342 27 2.329273 1.84 Pfam 241-270 (270) Show / Hide 
Range on Protein: 310-342
Range on HMM: 241-270/270
Sequence Identity: 27% (9 aa)

CPMELYSVCELARLCTQRESSSRPSMRDVSDLL
|| |.|   .| ..| . . . ||.....   |
CPDEIY---DLMKQCWHYDPEDRPTFSEIHEQL