IRAK-Un_dp

Species: S.moellendorffii
Alias: IRAK-Un_dp
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_dp.AA Protein None 324 None Fasta, JSON
IRAK-Un_dp.NA RNA None 975 None Fasta, JSON
IRAK-Un_dp.kin_dom Protein Kinase Domain None 199 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_dp.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_dp.AA IRAK 47-317 27 1.6e-59 204.09 In-house 1-317 (317) Show / Hide
Range on Protein: 47-317
Range on HMM: 1-317/317
Sequence Identity: 27% (87 aa)

FSENRRLGDGGFGTVYAGTLGGGGDVVAVKLLHR----SPQQASPQFMA---EIDILSRFKHPNLVQLLGCSTDGQSLLLVYEFVGNGTLADHLHTKKS-
|....|.| ||||.|| | . . . ..|||.|.     |. .   .| .   |. ...|. |||.| |.| .|..| . |||..  ||.| | |.  .  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-R---LPWLTRLAIAIDIAQVLAYLHSYS----ILHRDVKSTNVLLDEGFHAKLGDFGLSKAAAAAAAVEGHVS-----IGAQGTAGYLDPEYHQ--CYA
     |.| .|. |.. .|  . .||. .    | |.|.|| |.|||. | .|..||||      | . | ...        .||. |. ||.       
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTDKSDVYSFGVLLMELITAK-PAVDFSRERVNLAPYAVGMLQAGAF----------------------EQIIDPHLEAARNCMVRAMALRVAEIAFQCL
|| |.||||||. |.|..|   ...| ..|   |  .     .  .                        ||.  ..    . ....|..  .  | .|.
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQCACCCG

AANPEDRPRMGEVAAAL
..    |. | .| . |
HHRANRRCDMAWVMQQL

Kinase IRAK-Un_dp.AA TKL 53-317 21 1.1e-58 201.27 In-house 1-364 (364) Show / Hide
Range on Protein: 53-317
Range on HMM: 1-364/364
Sequence Identity: 21% (83 aa)

LGDGGFGTVYAGTLGGGG--------DVVAVKLLHR---------------------------SPQQASPQFMAEIDILSRFKHPNLVQLLGCSTDGQS-
.| ||||.|| |.. | |         .|||| ...                            ....  ..  || ..||..|||.||..|....... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LLLVYEFVGNGTLADHLHTKKSRLPWLTRLAIAIDIAQVLAYLHSYS--------ILHRDVKSTNVLLDEGFH--------------A
            | .|.|.. .|.| ..||       |  |. .|.|||. ..||||          |.||| || |.|.|| ..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLGDFGLSK-------------------AAAAAAAVEGHVSIGAQGTAGYLDPEY----------------HQCYALTDKSDVYSFGVLLMELITAKPAV
|..|||||.                   .   .. . .  ..   || ... ||                  ...  . |.||||||..| |..| ..  
KICDFGLSRFMSQSGNMNDTMTTMMESAE---HQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

DFSRERVNLAPYA-VGMLQAGAF-------EQIIDPHLEAARN---------CMVRAMALRVAEIAFQCLAANPEDRPRMGEVAAAL
          ||.  .. .  ..       ....|  |   .          |    .  ...... .| ...||.|| . |.   |
----------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase IRAK-Un_dp.AA Pkinase 47-245 28 2.5e-46 164.89 Pfam 1-210 (293) Show / Hide
Range on Protein: 47-245
Range on HMM: 1-210/293
Sequence Identity: 28% (61 aa)

FSENRRLGDGGFGTVYAGTLGGGGDVVAVKLLHRSPQQASPQFMA-----EIDILSRFKHPNLVQLLGCSTDGQSLLLVYEFVGNG----TLADHLH-TK
.   |..| |.||.|| ..  | |..|||| . ..  . | . ..     || |. |..||| |.|... .|.... .| |....|     |.|...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KSRL--PWLTRLAIAIDIAQVLAYLHSYSILHRDVKSTNVLLDEGFHA----KLGDFGLSKAAAAAAAVEGHVSIGAQGTAGYLDPEYHQ-CYALTDKSD
. ..  .. .   ..  |.. |.|.|| .|.|||.|. |.|.|.  |     |..||||.| .       ..   .  || .|. || .. .   . |.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSFGVLLMELITAKP
..|.|..| |... .|
MWSCGCILYEMLCGRP

Kinase IRAK-Un_dp.AA S_TKc 47-318 24 1.6e-45 158.51 SMART 1-231 (231) Show / Hide
Range on Protein: 47-318
Range on HMM: 1-231/231
Sequence Identity: 24% (70 aa)

FSENRRLGDGGFGTVYAGTLGGGGDVVAVKLLHRSPQQASPQFMAEIDILSRFKHPNLVQLLGCSTDGQSLLLVYEFVGN--GTLADHLHTKKSR-----
.   | .| |.||.|| ..  . | .||.| ..        ... ||.||.. .|||.|.|...  | ..| .| |....  |.| |... ....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LPWLTRLAIAIDIAQVLAYLHSYSILHRDVKSTNVLLDEGFHAKLGDFGLSKAAAAAAAVEGHVSIGAQGTAGYLDPEYHQCYALTD-KSDVYSFGVLLM
.|  .   ..  |.. |.|.||  |.|||.|  |.||||  | |..||||..                 ||  |. ||       .  |.|..|.|..| 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELITAKPAVDFSRERVNLAPYAVGMLQAGAFEQIIDPHLEAARNCMVRAMALRVAEIAFQCLAANPEDRPRMGEVAA--------ALI
|... .|  .                ..  |..|                   . ..  .||  .||.||   |. .          .
EMLCGYPPFP---------------QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IRAK-Un_dp.AA TK 47-317 16 2.7e-45 149.36 In-house 1-486 (486) Show / Hide
Range on Protein: 47-317
Range on HMM: 1-486/486
Sequence Identity: 16% (81 aa)

FSENRRLGDGGFG---TVYAGTLGGGG-------------------------DVVAVKLLHRSPQQASPQFMA--------------EIDILSRFK----
    . || | ||   .|| |.. |..                           |||| |.    ... .|..              |  ... ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVQLLGCSTDGQS------------LLLVYEFVGNGT----LADHLHTK-----------------------------------------------
 |||.|.|.|..|.|..            ...| |.. .|     | |.|...                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------KSRLPWLTRLAIAIDIAQVLAYLHSY------SILHRDVKSTNVLLDEGFH-----------AKLGDFGLSK
                            |..|.  ..| .. .||. ..||||        . |||.   |.|..|. .           .|..|||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----AAAAAAAVEGHVSIGAQGTAG-------------------------YLDPEYHQCYA---------LTDKSDVYSFGVLLMELIT---AKPAVDF
      | .    .  .. . .||..                         .. ||  .             | ||||.|||||. |. |   . .. . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SRERVNLA---PYAVGMLQAG-------AFEQIIDPHLEAA-RNCM---------VRAMALRVAEIAFQCLAANPEDRPRMGEVAAAL
| ..|  .      . .|..|         ... . .  ..  .|           ...   ....  || ...|||||.. ..  .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGL-NEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase IRAK-Un_dp.AA Pkinase_Tyr 47-192 31 4.7e-40 136.27 Pfam 1-160 (270) Show / Hide
Range on Protein: 47-192
Range on HMM: 1-160/270
Sequence Identity: 31% (51 aa)

FSENRRLGDGGFGTVYAGTLG----GGGDVVAVKLL-HRSPQQA--SPQFMAEIDILSRF-KHPNLVQLLGCST-DGQS--LLLVYEFVGNGTLADHLHT
 . .. || | ||.|| ||.     ...  |||| | . . ...  .  ||.|. |.. . .|||.|.|.|. | .|..  ...| |.. .| | |.|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K---KSRLPWLTRLAIAIDIAQVLAYLHSYSILHRDVKSTNVLLDEGFHAKLGDFGLSKA
.   | .|.  . | ....||. ..||.|  . |||.   |.|..|....| .||||...
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD

Kinase IRAK-Un_dp.AA TKL-Unique 51-244 30 2.4e-39 136.41 In-house 3-225 (290) Show / Hide
Range on Protein: 51-244
Range on HMM: 3-225/290
Sequence Identity: 30% (69 aa)

RRLGDGGFGTVYAGTLGGGGDVVAVKLLH-RSPQQAS--PQFMAEIDILSRFK-HPNLVQLLGCST----DGQSLLLVYEFVGNGTLADHLH--------
  .| ||.|.|| |.  . |. ||.| .|  . .  .    |  |. ...... |||.|.. | ..    .   . .| |..  |.| |.||        
NKIGEGGYGQVYKGK--WRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-TKKSRLPWLTRLAIAIDIAQVLAYLHSYS--ILHRDVKSTNVLLDEG-----FHAKLGDFGLSKAAA--AAAAVEGHV---SIGAQGTAGYLDPEYHQC
  ... |... |. .||||||.. |||...  |.||| ||.|.|.|..     . .|. |||||| ..   .  . .|      . .|.. .. ||    
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--YALTDKSDVYSFGVLLMELITAK
  .  . ||||||||. | |..| |
NFCQYSEKSDVYSFGIVLWEIATRK

Kinase IRAK-Un_dp.AA LISK 52-191 34 6.8e-38 120.56 In-house 1-153 (296) Show / Hide
Range on Protein: 52-191
Range on HMM: 1-153/296
Sequence Identity: 34% (53 aa)

RLGDGGFGTVYAGTLGGGGDVVAVKLLHR-----SPQQASPQFMAEIDILSRFKHPNLVQLLGCSTD-GQSLLLVYEFVGNGTLADHLHT---KKSRLPW
 .| |.|| || ||.   | |.|.| .||         .   .  |. .. .. ||| ||  | .     .| .| |... |.| . |.    .|. |||
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

LTRLAIAIDIAQVLAYLHSYSILHRDVKSTNVLLD----EGFHAKLGDFGLSK
  |. || |||. ..||||  |.||| ||.|.|..    ... .|..|||. .
PQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFAR

Kinase IRAK-Un_dp.AA LRRK 47-248 26 1.5e-37 130.43 In-house 1-284 (351) Show / Hide
Range on Protein: 47-248
Range on HMM: 1-284/351
Sequence Identity: 26% (76 aa)

FSENRRLGDGGFG-TVYAGTLGG--------------------------GGDVVAVKLLHRSP----------------------------------QQA
. ... .|.|||| .|| ... |                           .  ||.| ..| |                                    |
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

SPQFMAEIDILSRFKHPNLVQLLGCSTDGQSLLLVYEFVGNGTLADHLHTKK-SR-------LPWLTRLAIAIDIAQVLAYLHSYS--ILHRDVKSTNVL
   |  |. |.|...|||.|.|.| . .   | .| |.. .|.| ..|| || ..       ..| ..| ||..||  ..|||| .  |.||| || |.|
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

L---D---------EGFHAKLGDFGLSKAAAAAAAVEGHVSIGAQGTAGYLDPEYHQCY---ALTDKSDVYSFGVLLMELITAK-PAVD
|   .         .  .||..|||.|      ...   |  |  |. |.. ||  .       |.|.|.||||..| ||.| . .. |
LWSSPQNHSPNYPNAHVCAKIADFGISR-MF--QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD

Kinase IRAK-Un_dp.AA TK-Unique 47-191 26 1.5e-35 120.09 In-house 1-181 (294) Show / Hide
Range on Protein: 47-191
Range on HMM: 1-181/294
Sequence Identity: 26% (48 aa)

FSENRRLGDGGFGTVYAGTLGGGG------DVVAVKLLHRSPQQAS-PQFMAEIDILSRFK-HPNLVQLLGCSTDGQ-SLLLVYEFVGNGTLADHLHTKK
.  ....|.| ||.|. |.. |.       ..||||.|... .. .  .|. || ...  . |||.||.|||.|. . . ....|.. .|.| ..|.|..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

SR-------------------------LPWLTRLAIAIDIAQVLAYLHS--YSILHRDVKSTNVLLDEGFHAKLGDFGLSK
                           .   . . .|..||. ..||.|  . | |||. . |||| |.. .|..|||...
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMAR

Kinase IRAK-Un_dp.AA Dicty5 89-246 33 1.7e-35 119.62 In-house 43-202 (260) Show / Hide
Range on Protein: 89-246
Range on HMM: 43-202/260
Sequence Identity: 33% (55 aa)

FMAEIDILSRFK--HPNLVQLLGCSTDGQSL-LLVYEFVGNGTLADHLHTKKS----RLPWLTRLAIAIDIAQVLAYLHSYSILHRDVKSTNVLLDEGFH
|  |. |.| |.  |||..  .|  .  .     | |.. ||.| . |  ..      . . ..| .|||||| . .||| .| |||.|| |.|. | . 
FYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWK

AKLGDFGLSKAAAAAAAVEGHVSIGAQGTAGYLDPEYHQCYALTDKSDVYSFGVLLMELITAKPA
.|. ||| |   ...     ||     ||  .  .|  .    ..| ||||||. | |..| | .
IKIIDFGTSRFVDNRYHMTMHV-----GTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEP

Kinase IRAK-Un_dp.AA TyrKc 47-317 25 3.4e-35 124.16 SMART 1-280 (280) Show / Hide
Range on Protein: 47-317
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

FSENRRLGDGGFGTVYAGTLGGGGDVVAVKLLHRSPQQASPQFMAEIDILSRF--KHPNLVQLLGCSTDG-------QSLLLVYEFVGNGTLADHLHTKK
 . .. || | ||.|| ||.      |||| |. .       || |. |....  .|||.|.|.|. |..       . |..| |.. .| | |.|. ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

SRLPWLTRLAIAIDIAQVLAYLHSYSILHRDVKSTNVLLDEGFHAKLGDFGLSKAAAAA-----AAVEGHVS--IGAQ--GTAGYLDPEYHQCYALTDKS
 .|.. . | ....||.  .||||  . |||    |.|..|....| .|||||..         .    ...   |.        . ||  . .  | ||
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVYSFGVLLMELITAKPAVDFSR---ERVNLAPYAVGMLQAGAFEQIIDPHLEAARNCMVRA----MALRVAEIAFQCLAANPEDRPRMGEVAAAL
||.||||.. |. |   .   .    . .  .  ..  ...|    . . ..              .   . .|  || ...|||||.. |.   .
DVWSFGVCMWEIFT-YGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY-------P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase IRAK-Un_dp.AA UTK 51-194 29 1.3e-29 98.52 In-house 5-179 (296) Show / Hide
Range on Protein: 51-194
Range on HMM: 5-179/296
Sequence Identity: 29% (52 aa)

RRLGDGGFGTVYAGTLG-----GGGDVVAVKLLH-RSPQQASP----QFMAEID---ILSRFK-HPNLVQLLGCSTDGQSLLLVYEFVGNGTLADHLHTK
|.|| | ||.|. ...      .. ..|||| .  ... | .|    .|| |     ....|. |||...|.|  |... ...|.|.  || |.. | . 
RQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRH

KS----RLPWLT---RLAIAIDIAQVLAYLHSYSILHRDVKSTNVLLDEG-------FHAKLGDFG---LSKAAA
.     .  |||   ||  | |||  ..||||  . |||.   |.|...          .|..|||   .|....
RPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVN

Kinase IRAK-Un_dp.AA MLK 47-191 25 1.8e-28 95.96 In-house 1-181 (291) Show / Hide
Range on Protein: 47-191
Range on HMM: 1-181/291
Sequence Identity: 25% (46 aa)

FSENRRLGDGGFGTVYAGTLGGGG---DVVAVKLLHRSPQQASPQ-------FMAEIDILSRFKHPN----LVQLLGCSTDGQS-LLLVYEFVGNGTLAD
. . . .| |.|| |. |.  .      .||||  . ..  .. .       |  |. .|....|||     .|..|.... .. ...| |.. .| |..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLHTKKS-------------RLPWLTRLAIAIDIAQVLAYLHSYS---ILHRDVKSTNVLLDE------GFHAKLGDFGLSK
 ||...|             . .    . .| ..|. ..||||     | ||| || |.|.||      . ..|  |||.|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR

Kinase IRAK-Un_dp.AA LISK 225-246 45 9e-06 14.46 In-house 217-238 (296) Show / Hide
Range on Protein: 225-246
Range on HMM: 217-238/296
Sequence Identity: 45% (10 aa)

TDKSDVYSFGVLLMELITAKPA
....||.|||..| |.|| . |
DESCDVFSFGIVLCEIITRVKA

Kinase IRAK-Un_dp.AA UTK 225-242 61 2.1e-05 14.43 In-house 218-235 (296) Show / Hide
Range on Protein: 225-242
Range on HMM: 218-235/296
Sequence Identity: 61% (11 aa)

TDKSDVYSFGVLLMELIT
| ||||.||||...|. |
TTKSDVWSFGVVCWEIWT

Kinase IRAK-Un_dp.AA MLK 227-242 56 0.000208 11.35 In-house 216-231 (291) Show / Hide
Range on Protein: 227-242
Range on HMM: 216-231/291
Sequence Identity: 56% (9 aa)

KSDVYSFGVLLMELIT
|.||.|.||.| |..|
KCDVWSWGVVLWEMLT

Kinase IRAK-Un_dp.AA Pkinase_Tyr 225-242 66 0.000268 15.18 Pfam 192-209 (270) Show / Hide
Range on Protein: 225-242
Range on HMM: 192-209/270
Sequence Identity: 66% (12 aa)

TDKSDVYSFGVLLMELIT
| ||||.|||||. |..|
TTKSDVWSFGVLMWEIFT

Kinase IRAK-Un_dp.AA UTK 286-317 15 0.000297 10.46 In-house 265-296 (296) Show / Hide
Range on Protein: 286-317
Range on HMM: 265-296/296
Sequence Identity: 15% (5 aa)

RAMALRVAEIAFQCLAANPEDRPRMGEVAAAL
... ..| ..  .| ...|..||.. .. ...
WDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase IRAK-Un_dp.AA MLK 298-317 30 0.000738 9.42 In-house 272-291 (291) Show / Hide
Range on Protein: 298-317
Range on HMM: 272-291/291
Sequence Identity: 30% (6 aa)

QCLAANPEDRPRMGEVAAAL
||  ..|..|| . ..   |
QCWNQDPHKRPSFRQIVQHL

Kinase IRAK-Un_dp.AA TK-Unique 227-242 68 0.002923 7.24 In-house 219-234 (294) Show / Hide
Range on Protein: 227-242
Range on HMM: 219-234/294
Sequence Identity: 68% (11 aa)

KSDVYSFGVLLMELIT
||||.|||||. |. |
KSDVWSFGVLMWEIFT

Kinase IRAK-Un_dp.AA Pkinase_Tyr 298-317 45 0.00803 10.18 Pfam 251-270 (270) Show / Hide
Range on Protein: 298-317
Range on HMM: 251-270/270
Sequence Identity: 45% (9 aa)

QCLAANPEDRPRMGEVAAAL
|| ...|||||.. |.   |
QCWHYDPEDRPTFSEIHEQL

Kinase IRAK-Un_dp.AA TK-Unique 298-317 30 0.061327 2.62 In-house 275-294 (294) Show / Hide
Range on Protein: 298-317
Range on HMM: 275-294/294
Sequence Identity: 30% (6 aa)

QCLAANPEDRPRMGEVAAAL
.|.  .||.||   ...  |
SCWQWEPEERPSFRQIKHRL

Kinase IRAK-Un_dp.AA TKL-Unique 298-317 35 0.161811 1.34 In-house 271-290 (290) Show / Hide
Range on Protein: 298-317
Range on HMM: 271-290/290
Sequence Identity: 35% (7 aa)

QCLAANPEDRPRMGEVAAAL
|| . .|..||   |.   |
QCWHHDPSQRPSFDEIIHRL