Gene IRAK-Un_bk-2 (S.moellendorffii)

IRAK-Un_bk-2

Species: S.moellendorffii
Alias: IRAK-Un_bk-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_bk-2.AA Protein None 893 None Fasta, JSON
IRAK-Un_bk-2.NA RNA None 2682 None Fasta, JSON
IRAK-Un_bk-2.kin_dom Protein Kinase Domain None 150 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_bk-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 IRAK-Un_bk-2.AA LRR_1 111-133 25 48.049006 0.78 Pfam 1-26 (26) Show / Hide 
Range on Protein: 111-133
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

LLRYLNASGF--HAR-GLLPYW-IGEL
 |..|. ||.  .   | .| . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-Un_bk-2.AA LRR_1 135-158 48 3.8e-05 22.41 Pfam 1-26 (26) Show / Hide 
Range on Protein: 135-158
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

QLQVLDLSSC--SGLQGSIPDS-LGQL
.||.||||.|  . |.|.||.| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-Un_bk-2.AA LRR_1 160-182 51 0.000164 20.17 Pfam 1-26 (26) Show / Hide 
Range on Protein: 160-182
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

QLKFLSLSG-N--NLTGGLPYS-LGNL
.|. |.||| |  |||| .| | . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-Un_bk-2.AA LRR_1 184-206 40 0.005283 14.82 Pfam 1-26 (26) Show / Hide 
Range on Protein: 184-206
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ALEALNLSS-N--GLSGGIPGS-FQAM
 |. |.||. |   |.| || | | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP IRAK-Un_bk-2.AA LRR_TYP 206-228 37 0.048533 10.62 SMART 1-24 (24) Show / Hide 
Range on Protein: 206-228
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

MRRLVTLDVSRNLLDGLP-RLGSG
.. | .|| |.| |  || .. .|
LPNLRELDLSNNQLTHLPPGAFQG
LRR_TYP IRAK-Un_bk-2.AA LRR_TYP 158-181 37 0.117951 7.46 SMART 1-24 (24) Show / Hide 
Range on Protein: 158-181
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

LRQLKFLSLSGNNLTGGLPYSLGN
|..|. |.||.|.||   |  ...
LPNLRELDLSNNQLTHLPPGAFQG
LRR_TYP IRAK-Un_bk-2.AA LRR_TYP 182-205 45 0.117951 7.46 SMART 1-24 (24) Show / Hide 
Range on Protein: 182-205
Range on HMM: 1-24/24
Sequence Identity: 45% (11 aa)

LVALEALNLSSNGLSGGIPGSFQA
|..|. |.||.| |.   || || 
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 IRAK-Un_bk-2.AA LRR_1 208-228 25 10.529986 3.12 Pfam 1-26 (26) Show / Hide 
Range on Protein: 208-228
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RLVTLDVSR-N--LL-DGLPR--LGSG
.| .||.|. |   | . .|   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-Un_bk-2.AA LRR_1 242-264 33 9.1e-05 21.07 Pfam 1-26 (26) Show / Hide 
Range on Protein: 242-264
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RIEVLDLSS-N--RINGSLPPE-LGKL
....||||. |  .. |..||. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-Un_bk-2.AA LRR_1 266-288 40 0.000296 19.26 Pfam 1-26 (26) Show / Hide 
Range on Protein: 266-288
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLRVLDLSR-N--SLGGTIPAG-IGSL
.|..||||. |  .| |.|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAK-Un_bk-2.AA LRR_1 290-312 40 0.000296 19.26 Pfam 1-26 (26) Show / Hide 
Range on Protein: 290-312
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLTKMDLSR-N--NLTGFLPRE-LSSL
.|.. |||. |  |||| .| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP IRAK-Un_bk-2.AA LRR_TYP 264-287 44 0.043863 10.98 SMART 1-24 (24) Show / Hide 
Range on Protein: 264-287
Range on HMM: 1-24/24
Sequence Identity: 44% (11 aa)

LASLRVLDLSRNSLGGTIPAGI-GS
| .||.||||.| |  ..|.|. ..
LPNLRELDLSNNQL-THLPPGAFQG
LRR_TYP IRAK-Un_bk-2.AA LRR_TYP 288-311 37 0.094203 8.26 SMART 1-24 (24) Show / Hide 
Range on Protein: 288-311
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

LARLTKMDLSRNNLTGFLPRELSS
|  |.. |||.|.||   |. ...
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 IRAK-Un_bk-2.AA LRR_1 314-336 25 0.177284 9.41 Pfam 1-26 (26) Show / Hide 
Range on Protein: 314-336
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RMEALVLSH-N--EFYGSLPEG-LTAL
. . | ||. |   . |..|.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP IRAK-Un_bk-2.AA LRR_TYP 312-336 32 0.407259 3.05 SMART 1-24 (24) Show / Hide 
Range on Protein: 312-336
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

LARMEALVLSHNEFYGSLPEGLTAL
|   . | ||.| .  .||.|. . 
LPNLRELDLSNNQL-THLPPGAFQG
LRR_TYP IRAK-Un_bk-2.AA LRR_TYP 240-263 32 0.862235 0.38 SMART 1-24 (24) Show / Hide 
Range on Protein: 240-263
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

FERIEVLDLSSNRINGSLPPEL-GK
    ..||||.|..  .|||.. . 
LPNLRELDLSNNQL-THLPPGAFQG
Kinase IRAK-Un_bk-2.AA TKL 516-792 17 7.6e-29 100.99 In-house 1-364 (364) Show / Hide 
Range on Protein: 516-792
Range on HMM: 1-364/364
Sequence Identity: 17% (67 aa)

IKAGHTGDLYRGILDG---------GLLVVVKRVDVTSLKK----------------------------DFLLSELEFFSKASHTRLVPLLGHCLEREN-
|  |. |  |.|.. |         |  |.||.  ... ..                            .|.  |.   |. .|  .|...| |.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------EKFLVYKYMQHGDLARALHRKIVPSPPKDILQSLDWITRLKIAIGAAEGLSYLHHECS-----PALVHRDIKATSILLDDKFE------
           . ..|. |...|.|   ||                |  |...|...| |..||| .       |...|||.|   ||.|....      
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYM

--------VRLGSLSEARIQDGGVHPNLIM-------------------R---------FLRSRSQTSEQ---DPDS---PVASCAYDVYCFGKVLLELV
        . .. .  .|  ..  . | .|                   .          ||   ...|    |.       .| . ||| || || |..
YNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEIL

SGKLGISGTMDPGADTWVETILPLIDRHEKENLSKIVDSSLLVDDD----------LLEEVWA-VAIVAKMCLNPKPSRRPAIRQVLKAL
....       | .| . .....     ..| .....| .|    .            . ..  ..  ...| ...|. ||   ..|| |
TRCR-------PYYDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-Un_bk-2.AA IRAK 510-655 32 7.8e-18 59.92 In-house 1-151 (317) Show / Hide 
Range on Protein: 510-655
Range on HMM: 1-151/317
Sequence Identity: 32% (50 aa)

FNPVNLIKAGHTGDLYRGILDGGL-LVVVK------RVDVTSLKKDFLL--SELEFFSKASHTRLVPLLGHCLERENEKFLVYKYMQHGDLARALHRKIV
|.. |.|  |  |. ||| ...    ..||       .  ..... |.    ||.  ..  |  .|||.| |.||. .  ||| ||  | |   |.    
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQ-CHCLVYPYMPNGSLEDRLWCQDG

PSPPKDILQSLDWITRLKIAIGAAEGLSYLHHECSP-ALVHRDIKATSILLDDKFE
  |||     | |..|..|..|.| |. .||   .  .. |.|||   ||||. |.
QCPPK----PLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFT
Kinase IRAK-Un_bk-2.AA TK 510-659 14 8.1e-15 45.36 In-house 1-293 (486) Show / Hide 
Range on Protein: 510-659
Range on HMM: 1-293/486
Sequence Identity: 14% (43 aa)

FNPVNLIKAGHTG---DLYRGILDGGL--------------------------LVVVKRVDV--TSLKKDFLL----------------SELEFFS--KA
   .. . .|. |   . |.|.. |.                            | || .    .. ...|..                .|.. ..  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHTRLVPLLGHCLERE-----------NEKFLVYKYMQHGD----LARALHRKIV---------------------------------------------
 |  .| |.|.|.. |               .|  ||.|||    |   |...                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------PSPPKDILQ-----------SLDWITRLKIAIGAAEGLSYLHHE-CSPA---LVHRDIKATSILLDDKFE-----------VRLG
          | . || ||            |.  ..| ..  .|.|..|||   |.     .||||. |  .|....             ....
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIA
Kinase IRAK-Un_bk-2.AA MLK 510-656 21 8.9e-15 47.81 In-house 1-171 (291) Show / Hide 
Range on Protein: 510-656
Range on HMM: 1-171/291
Sequence Identity: 21% (37 aa)

FNPVNLIKAGHTGDLYRGILDGGL----LVVVKRVD-------VTSLKKDFLLSELEFFSKASHTR----LVPLLGHCLERENEKFLVYKYMQHGDLARA
..    | .|. |. ..|   . .     | ||||.       .|.  .. .  | . ... ||       ....| ||. ... ..|  |...| |.. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHR-KIVPS------PPKDILQSLDWITRLKIAIGAAEGLSYLHHECSPALVHRDIKATSILLDD-----KFEV
||  .. ..      .  |. ...| .  ...|   |.|..||| .  ....|||.|   ||.|.     . ..
LHGARSKWMDANHNQK-NDRVYDHDHA--MNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGT
Kinase IRAK-Un_bk-2.AA TyrKc 513-792 16 5.6e-11 -45.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 513-792
Range on HMM: 1-280/280
Sequence Identity: 16% (54 aa)

VNLIK---AGHTGDLYRGILDGGLLVVVKRVDVTSLKKDFLLSELEFFSKA--SHTRLVPLLGHCLERE------NEKFLVYKYMQHGDLARALHRKIVP
. |.|    |. |  |.|...  . | || .   .  .  ...|..  .|   .|  .| |.| |.. .         ..|  || ||||   |...   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

SPPKDILQSLDWITRLKIAIGAAEGLSYLHHECSPALVHRDIKATSILLDDKFEVRLGSLSEARIQDGGVHPNLIMRFLRSR-------SQTSEQ---DP
         | . . |.... .|.| .|||.     ..|||. |  .|.....         ..| | |      .|.. .        .  . .   . 
---------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH--------TVKISDFG-----LSRDIYDDDQQGESKDYYRKKEHKGG

D--SPV------ASCAY------DVYCFGKVLLELVSGKLGISGTMDPGA-----DTWVETILPLIDRHEKENLSK-----IVDSSLLVDDDLLEEVWAV
.   |.      .   .      ||. || .. |. .      | . .        .. | |  . ...  .                      .   ..
KTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTY-----GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-----------VCCPDEM

AIVAKMCLNPKPSRRPAIRQVLKAL
  . |.| . .|. ||  ... . .
YQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAK-Un_bk-2.AA Pkinase_Tyr 525-643 24 1.2e-10 36.67 Pfam 16-137 (270) Show / Hide 
Range on Protein: 525-643
Range on HMM: 16-137/270
Sequence Identity: 24% (32 aa)

YRGILD-----GGLLVVVKRV--DVTSL---KKDFLLSELEFFSKA-SHTRLVPLLGHCL-EREN-EKFLVYKYMQHGDLARALHRKIVPSPPKDILQSL
|.|...     ... | || .  . ..    ..||.  |..  ..  .|  .| |.| |. ..|  . ..|  ||.||||   |...       .  |.|
YKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR------EDKQPL

DWITRLKIAIGAAEGLSYLHHECSPALVHRDI
.  . |....  |.|..||.      ..|||.
TMKDLLQMCWQIAKGMEYLESKN---CIHRDL
Kinase IRAK-Un_bk-2.AA MLK 510-655 26 2.4e-10 30.19 In-house 1-141 (280) Show / Hide 
Range on Protein: 510-655
Range on HMM: 1-141/280
Sequence Identity: 26% (40 aa)

FNPVNLIKAGHTGDLYRGILDGGLLVVVK-----RVDVTSL--KKDFLLSELEFFSKASHTRLVPLLGHCLERENEKFLVYKYMQHGDLARALHRKIVPS
 .   .| .|  |  ||.  .| .  |       . |. .   . . .  |   |   .|   . |.| ||| . .  ||  | . | | |..  | .  
LKIKEIIGNGGFGKVYRAQWKGEEVAVKAHRQDPEQDMQQTDEQAEQVRQEARLFWMLKHPNIIALRGVCLE-DPHLCLVMEYCRGGSLNRVCAGKRI--

PPKDILQSLDWITRLKIAIGAAEGLSYLHHECSPALVHRDIKATSILLDDKFE
 | ..|   .|      |.  |.|. |||.|   ...|||.|.  ||. .| .
-PPHVL--VNW------AVQIARGMNYLHNEAPVPIIHRDLKSSNILILEKIC
Kinase IRAK-Un_bk-2.AA S_TKc 510-798 13 4.3e-10 -28.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 510-798
Range on HMM: 1-231/231
Sequence Identity: 13% (43 aa)

FNPVNLIKAGHTGDLYRGILDG-GLLVVVKRVDVTSLKKDFLLSELEFFSKASHTRLVPLLGHCLERENEKFLVYKYMQH--GDLARALHRKIVPSPPKD
.  ...|  |  |  |...  . | .| .|...      . ...|..  .|  |  .| |.... .  .. ..|  |. .  ||| . ....  . ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR--

ILQSLDWITRLKIAIGAAEGLSYLHHECSPALVHRDIKATSILLDDKFEVRLGSLSEARIQDGGVHPNLIMRFLRSRSQTSEQDPDSPVAS---------
  . ..  .  ...   ...| |.|       .|||.|   ||||.  .. ..    ||.                         .. . .         
--FPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL------------------------TTFCGTPWYMAPEVL

---C-AYDVYCFGKVLLELVSGKLGISGTMDPGADTWVETILPLIDRHEKENLSKIVDSSLLVDDDLLEEVWAVAIVAKMCLNPKPSRRPAIRQVLK---
   . . |.. .| .| |...|.   .       ..  . |.                              |     . ||.  |..|| . ..|.   
GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG---------------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEW

ALENPQRV
.  . . .
DIKCHPWF
Kinase IRAK-Un_bk-2.AA LRRK 585-650 36 6e-09 27.78 In-house 136-199 (351) Show / Hide 
Range on Protein: 585-650
Range on HMM: 136-199/351
Sequence Identity: 36% (26 aa)

YMQHGDLARALHRKI------VPSPPKDILQSLDWITRLKIAIGAAEGLSYLHHECSPALVHRDIKATSILL
|..|||| . || |       ..        ...| ..||||.  |.|. || | ..| ..||| |   |||
YAPHGDLYHFLHNKKQDGFHFMK-------AHISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDLKSPNILL
Kinase IRAK-Un_bk-2.AA STE 510-658 18 6.4e-09 27.76 In-house 1-188 (359) Show / Hide 
Range on Protein: 510-658
Range on HMM: 1-188/359
Sequence Identity: 18% (36 aa)

FNPVNLIKAGHTGDLYRGILDG----------------GLLVVVKRVDVTS------------------LKKDFLLSELEFFSKAS--HTRLVPLLGHCL
.  .  |  | .|  |...                   | .. .|.... .                   ... .| |... .| .  |   |  .|...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ER------ENEKFLVYKYMQHGDLARALHRKIVPSPPKD------ILQSLDWITRLKIAIGAAEG-LSYLHHECSPALVHRDIKATSILLDDKFEVRL
        ..| ...  ||  | |   ...|  .  | .         . ..|   .|.    .| |.|||       .|||||.  |||     | |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIA--YICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKL
Kinase IRAK-Un_bk-2.AA TKL-Unique 512-658 25 6.4e-09 27.78 In-house 1-158 (290) Show / Hide 
Range on Protein: 512-658
Range on HMM: 1-158/290
Sequence Identity: 25% (40 aa)

PVNLIKAGHTGDLYRGILDGGLLVVVKRVDV---TSLKKDF-LLSELEFFSKAS-HTRLVPLLGHCLE---RENEKFLVYKYMQHGDLARALHRKIVPSP
..|.|..|  |  |.|.   |  | .|.  .    |... . . .|.   .|   |  .| . | |      ... ..|  |...| |   ||.    . 
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

PKDILQSLDWITRLKIAIGAAEGLSYLHHECSPALVHRDIKATSILLDDK-----FEVRL
       |..  |.|.|| .| |. ||||.  |   |||.| ...|.| .     . ...
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKI
Kinase IRAK-Un_bk-2.AA DRK 610-656 34 1.8e-08 24.84 In-house 94-139 (258) Show / Hide 
Range on Protein: 610-656
Range on HMM: 94-139/258
Sequence Identity: 34% (16 aa)

SLDWITRLKIAIGAAEGLSYLHHECSPALVHRDIKATSILLDDKFEV
..||  ...... .| |. || | | |  .||| |    | |. . |
EMDWPLMKQMMFDCAKGMIYL-HCCNPIIIHRDLKSHNLLVDEHWQV
Kinase IRAK-Un_bk-2.AA Dicty4 610-656 36 9.1e-08 22.17 In-house 105-153 (277) Show / Hide 
Range on Protein: 610-656
Range on HMM: 105-153/277
Sequence Identity: 36% (18 aa)

SLDWITRLK---IAIGAAEGLSYLHHECSPALVHRDIKATSILLDDKFEV
.|||.....   .|. || |. .| |.| |  .|||.|.  .| |. . |
KLDWPLIKRAMRMAFDAARGMNWL-HCCNPVIIHRDLKSHNLLVDKNWRV
Kinase IRAK-Un_bk-2.AA Pkinase 530-659 18 0.000122 17.49 Pfam 22-154 (293) Show / Hide 
Range on Protein: 530-659
Range on HMM: 22-154/293
Sequence Identity: 18% (27 aa)

DGGLLVVVKRVDVTSLKKDFL-----LSELEFFSKASHTRLVPLLGHCLERENEKFLVYKYMQHG----DLARALHRKIVPSPPKDILQSL--DWITRLK
. | .|.||.... . |....     |||..   . .|   | |.. . . ...  .|  |...|    ||.. ...        .   ..  .. .  .
GTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST--------WRHGCFYFSEWECKF

IAIGAAEGLSYLHHECSPALVHRDIKATSILLDDKFEV----RLG
..   ..|| |.| .     .|||.|   ||.|.. ..    ...
YMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKIC
Kinase IRAK-Un_bk-2.AA DRK 774-794 38 0.000132 11.56 In-house 238-258 (258) Show / Hide 
Range on Protein: 774-794
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CLNPKPSRRPAIRQVLKALEN
|.|  |. ||   ..|. || 
CWNEDPQHRPSMQECLERLEA
Kinase IRAK-Un_bk-2.AA MLK 772-792 42 0.000391 10.39 In-house 271-291 (291) Show / Hide 
Range on Protein: 772-792
Range on HMM: 271-291/291
Sequence Identity: 42% (9 aa)

KMCLNPKPSRRPAIRQVLKAL
|.| |..|..||  ||... |
KQCWNQDPHKRPSFRQIVQHL
Kinase IRAK-Un_bk-2.AA Dicty4 774-794 26 0.000451 9.67 In-house 255-277 (277) Show / Hide 
Range on Protein: 774-794
Range on HMM: 255-277/277
Sequence Identity: 26% (6 aa)

CLNPKPSRRPAIRQVLKA--LEN
|... |..||   .....  || 
CWDHDPQHRPSFEEIIQRRILEH
Kinase IRAK-Un_bk-2.AA TK 766-792 22 0.000806 7.84 In-house 460-486 (486) Show / Hide 
Range on Protein: 766-792
Range on HMM: 460-486/486
Sequence Identity: 22% (6 aa)

AVAIVAKMCLNPKPSRRPAIRQVLKAL
..... ..| ...|..||  .|....|
EYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-Un_bk-2.AA TKL-Unique 772-792 28 0.01361 5.18 In-house 270-290 (290) Show / Hide 
Range on Protein: 772-792
Range on HMM: 270-290/290
Sequence Identity: 28% (6 aa)

KMCLNPKPSRRPAIRQVLKAL
..| .. || ||   .... |
QQCWHHDPSQRPSFDEIIHRL
Kinase IRAK-Un_bk-2.AA IRAK 701-715 66 0.050284 3.17 In-house 206-220 (317) Show / Hide 
Range on Protein: 701-715
Range on HMM: 206-220/317
Sequence Identity: 66% (10 aa)

DVYCFGKVLLELVSG
||| || ||||...|
DVYSFGIVLLEVLTG
Kinase IRAK-Un_bk-2.AA MLK 774-792 36 0.057026 2.04 In-house 262-280 (280) Show / Hide 
Range on Protein: 774-792
Range on HMM: 262-280/280
Sequence Identity: 36% (7 aa)

CLNPKPSRRPAIRQVLKAL
| |. | .||   ..|. |
CWNQDPHKRPKFSEILQQL
Kinase IRAK-Un_bk-2.AA TKL-Unique 697-717 47 0.066903 2.71 In-house 206-226 (290) Show / Hide 
Range on Protein: 697-717
Range on HMM: 206-226/290
Sequence Identity: 47% (10 aa)

SCAYDVYCFGKVLLELVSGKL
|.  ||| || || |....|.
SEKSDVYSFGIVLWEIATRKI
Kinase IRAK-Un_bk-2.AA Pkinase 774-792 33 0.103048 7.14 Pfam 273-293 (293) Show / Hide 
Range on Protein: 774-792
Range on HMM: 273-293/293
Sequence Identity: 33% (7 aa)

CLNPKPSRRPAIRQVLKA--L
||...|..|| ..|.|.   .
CLCKDPKKRPTAEQILQHPWF
Kinase IRAK-Un_bk-2.AA IRAK 774-792 26 0.13944 1.58 In-house 299-317 (317) Show / Hide 
Range on Protein: 774-792
Range on HMM: 299-317/317
Sequence Identity: 26% (5 aa)

CLNPKPSRRPAIRQVLKAL
|.  .  ||.....|.. |
CGHHRANRRCDMAWVMQQL
Kinase IRAK-Un_bk-2.AA LRRK 774-794 33 0.221026 0.63 In-house 331-351 (351) Show / Hide 
Range on Protein: 774-794
Range on HMM: 331-351/351
Sequence Identity: 33% (7 aa)

CLNPKPSRRPAIRQVLKALEN
| . .| .||   |..| |. 
CWQHDPKKRPHFSQIVKRLSQ
Kinase IRAK-Un_bk-2.AA Pkinase_Tyr 772-792 28 0.817591 3.38 Pfam 250-270 (270) Show / Hide 
Range on Protein: 772-792
Range on HMM: 250-270/270
Sequence Identity: 28% (6 aa)

KMCLNPKPSRRPAIRQVLKAL
|.| ...|..||  ....  |
KQCWHYDPEDRPTFSEIHEQL