Gene IRAK-Un_bg (S.moellendorffii)

IRAK-Un_bg

Species: S.moellendorffii
Alias: IRAK-Un_bg
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_bg.AA Protein None 253 None Fasta, JSON
IRAK-Un_bg.NA RNA None 762 None Fasta, JSON
IRAK-Un_bg.kin_dom Protein Kinase Domain None 71 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_bg.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_bg.AA IRAK 64-76 38 0.187294 1.12 In-house 1-13 (317) Show / Hide 
Range on Protein: 64-76
Range on HMM: 1-13/317
Sequence Identity: 38% (5 aa)

FSKSRSIGSGAIA
|.|.. ||.|...
FHKDNRIGEGGFG
Pkinase_Tyr IRAK-Un_bg.AA Pkinase_Tyr 160-223 28 6.2e-16 54.58 Pfam 1-73 (270) Show / Hide 
Range on Protein: 160-223
Range on HMM: 1-73/270
Sequence Identity: 28% (21 aa)

FSKECEVGCGGFGRVYRGNLE-----DGRTVAIKQASAKSKQGQ---REFRNEIQLLSRL-HHRHLVRLLGFC
 ..  . | | ||.||.| .      .. .||.|    .. . |   ..| .|..... | || ..|||.| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVC
Kinase IRAK-Un_bg.AA IRAK 160-223 30 1.3e-14 48.4 In-house 1-72 (317) Show / Hide 
Range on Protein: 160-223
Range on HMM: 1-72/317
Sequence Identity: 30% (22 aa)

FSKECEVGCGGFGRVYRGNLEDGR-TVAIK----QASAKSKQGQREFRN---EIQLLSRLHHRHLVRLLGFC
|.|.   | |||| |||| .     ..|.|     |. . ..  ..|.    |.....|..| ..| |.|.|
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYC
Kinase IRAK-Un_bg.AA LRRK 160-225 20 9.4e-13 41.43 In-house 1-128 (351) Show / Hide 
Range on Protein: 160-225
Range on HMM: 1-128/351
Sequence Identity: 20% (26 aa)

FSKECEVGCGGFG-RVYRGNLED---------------------------GRTVAIKQASAK----------------------------------SKQG
. .| ..| |||| .|||.....                           . .||||.                                      .   
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

QREFRNEIQLLSRLHHRHLVRLLGFCQS
 ||||.|. ..|.|.| ..| |.||| .
FREFRHEVWIMSHLNHPNIVSLKGFCIH
Kinase IRAK-Un_bg.AA TKL 166-228 21 1.7e-12 41.3 In-house 1-99 (364) Show / Hide 
Range on Protein: 166-228
Range on HMM: 1-99/364
Sequence Identity: 21% (21 aa)

VGCGGFGRVYRGNLED---------GRTVAIKQASAKSKQGQ---------------------------REFRNEIQLLSRLHHRHLVRLLGFCQSGKN
.| |||| ||.|..           |..||.|. . .. .                              ....|| ..|||.| ..|...|.|.....
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC
Kinase IRAK-Un_bg.AA ULK 160-228 22 2.1e-11 36.17 In-house 1-94 (329) Show / Hide 
Range on Protein: 160-228
Range on HMM: 1-94/329
Sequence Identity: 22% (21 aa)

FSKECEVGCGGFGRVYRG-NLED----GRTVAIKQASAKS-KQGQRE---------FRNEIQLLSRLH--------HRHLVRLLGFCQSG--KN
...  . | | ||.||.| | ..    .  ||.|. . .. .| . |         ..|||... .|.        | . |.|. ....   .|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNN
Kinase IRAK-Un_bg.AA TK 160-226 19 2.6e-11 33.37 In-house 1-115 (486) Show / Hide 
Range on Protein: 160-226
Range on HMM: 1-115/486
Sequence Identity: 19% (22 aa)

FSKECEVGCGGFG---RVYRGNLEDGR--------------------------TVAIKQASAKSKQGQREFRN-----------------EIQLLS--RL
   . . | | ||   .||.| .....                          .||.|.  ... . |.||.                  |.....   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHRHLVRLLGFCQSG
|| ..|||.| |  |
HHPNIVRLYGVCTQG
Kinase IRAK-Un_bg.AA ULK 160-228 23 5e-10 31.83 In-house 1-91 (324) Show / Hide 
Range on Protein: 160-228
Range on HMM: 1-91/324
Sequence Identity: 23% (22 aa)

FSKECEVGCGGFG-RVYRG-NLED---GRTVAIKQASAKSKQGQREF----------RNEIQLLSRLH------HRHLVRLLGFCQSG--KN
...  . | | ||  ||.| | ..   .  ||.|. . |. . .             .||||..  |.      | | |.|. ....   .|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNN
Kinase IRAK-Un_bg.AA CAMK 165-220 15 5.2e-10 27.72 In-house 1-104 (425) Show / Hide 
Range on Protein: 165-220
Range on HMM: 1-104/425
Sequence Identity: 15% (16 aa)

EVGCGGFGRVYRGNLE-DG------------RTVAIKQASAK----------------------------SKQGQREFRNEIQLLSR-------LHHRHL
. | |.|| |...    ..            . ||||  . |                            . . ....|.||.....       |.|...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLL
..|.
IKLY
Kinase IRAK-Un_bg.AA LISK 165-223 30 5.9e-10 28.32 In-house 1-65 (296) Show / Hide 
Range on Protein: 165-223
Range on HMM: 1-65/296
Sequence Identity: 30% (20 aa)

EVGCGGFGRVYRGNLE-DGRTVAIKQASA-----KSKQGQREFRNEIQLLSRLHHRHLVRLLGFC
| | |.|| ||.|..  .|. .|||. .      . .  |. .  |.|.. .| |.. |.  | |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVC
Kinase IRAK-Un_bg.AA STE20 160-221 21 1.3e-09 31.59 In-house 1-71 (288) Show / Hide 
Range on Protein: 160-221
Range on HMM: 1-71/288
Sequence Identity: 21% (15 aa)

FSKECEVGCGGFGRVYRGNL-EDGRT----VAIKQASAKSK----QGQREFRNEIQLLSRLHHRHLVRLLG
. .  ..| |..| ||...  . |.     ||||. . ...    . ...  .||. .....| . |. .|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYG
Kinase IRAK-Un_bg.AA MLK 160-225 23 1.3e-09 29.66 In-house 1-80 (291) Show / Hide 
Range on Protein: 160-225
Range on HMM: 1-80/291
Sequence Identity: 23% (19 aa)

FSKECEVGCGGFGRVYRGNLEDGR----TVAIKQAS----AKSKQG--QREFRNEIQLLSRLHHRH----LVRLLGFCQS
.  .  .| |.|| |..|.    .    .||.|..     .||. .  |..|. |. .|..| |.      ....| |..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQ
Kinase IRAK-Un_bg.AA Pkinase 160-228 27 2.5e-09 34.04 Pfam 1-74 (293) Show / Hide 
Range on Protein: 160-228
Range on HMM: 1-74/293
Sequence Identity: 27% (20 aa)

FSKECEVGCGGFGRVYRG-NLEDGRTVAIKQASAKSKQG--QREFRN--EIQLLSRLHHRHLVRLLGFCQSGKN
. ..  .| |.||.||.. .  .|..||.|. . ...    ... |.  |||.. ||.| . |||.........
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDH