Gene IRAK-Un_cj (S.moellendorffii)

IRAK-Un_cj

Species: S.moellendorffii
Alias: IRAK-Un_cj
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_cj.AA Protein None 736 None Fasta, JSON
IRAK-Un_cj.NA RNA None 2211 None Fasta, JSON
IRAK-Un_cj.kin_dom Protein Kinase Domain None 213 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_cj.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LysM IRAK-Un_cj.AA LysM 244-292 22 0.011042 6.66 SMART 1-45 (45) Show / Hide 
Range on Protein: 244-292
Range on HMM: 1-45/45
Sequence Identity: 22% (11 aa)

PYEIAPDDTTLFIIAKEKFQGLTRDDWIAEATPLKDKNTIFAGLNVKVP
 | . . | ||. ||. ...  .  . |... |... ..|..|   ..|
TYTVKKGD-TLWSIAQ-RYGITV--QDIMKWNPILNCDMIYPGQKLCIP
LysM IRAK-Un_cj.AA LysM 311-356 28 6.8e-10 40.11 SMART 1-45 (45) Show / Hide 
Range on Protein: 311-356
Range on HMM: 1-45/45
Sequence Identity: 28% (13 aa)

TYVVQPGDTLSTISARFKVPDQQLLQRFNPHIDFQRLIAQSIVFVP
||.|..||||. |..|....  | ... ||...  .. .     .|
TYTVKKGDTLWSIAQRYGITV-QDIMKWNPILNCDMIYPGQKLCIP
LysM IRAK-Un_cj.AA LysM 312-356 26 8.6e-08 30.39 Pfam 1-45 (45) Show / Hide 
Range on Protein: 312-356
Range on HMM: 1-45/45
Sequence Identity: 26% (12 aa)

YVVQPGDTLSTISARFKVPDQQLLQRFNPHIDFQR-LIAQSIVFVP
|.|..||||. |..|....  | ... ||... .. . .     .|
YTVKKGDTLWKIAQRYGTT-VQQIMEWNPNLKSPNHIYPGQKLCIP
Kinase IRAK-Un_cj.AA TKL 499-725 23 3.2e-53 183.13 In-house 88-364 (364) Show / Hide 
Range on Protein: 499-725
Range on HMM: 88-364/364
Sequence Identity: 23% (73 aa)

VQLIGYCTVES--------------LFLVYEFVDNGTLAQHLHSATRPPLSWSSRIQIAMDAARGLEYIHEHT-----KPTYIHRDIKSTNILIDKNLH-
||..|||. ..              |..|.|....|.|  .||        |. |...|.|.|||..| | ..     ||  ||||.|| |||.|.|.. 
VQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTN

-------------AKVADFGLSK-LTETG-MTSISLT------------QPTRLVGTFGYMSPEYARYG----------------DVSPFLDVYSFGVVL
             .|..|||||. ....| |. .. |            .  . .||...|.||  |                  . |.  ||||||.||
VSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL

FEIISAQEAIVRTQSGILSNKDEQKGLATLFEDVLQD------------DTNGKERLRDLMDPRLGD----NYPLEAAWSLAKLAGACTKENPELRPNMR
.||.. ..                      ..|   .              .....|| ...|.  .      .  .  |..||.  | ...|| ||.. 
WEILTRCR---------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQ

TVVVAL
...  |
EILKRL
Kinase IRAK-Un_cj.AA IRAK 499-725 28 6.7e-40 138.87 In-house 66-317 (317) Show / Hide 
Range on Protein: 499-725
Range on HMM: 66-317/317
Sequence Identity: 28% (72 aa)

VQLIGYCTVESLF-LVYEFVDNGTLAQHLHSATR--PP--LSWSSRIQIAMDAARGLEYIHEHT-KPTYIHRDIKSTNILIDKNLHAKVADFGLSKLT-E
| | |||| .. . |||..  ||.|   |.  .   ||  |||  |. |.  .|.|... |.   .   ||.|||| ||| |... .| .||||     .
VPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHP

TG---MTSISLTQPTRLVGTFGYMSPEYAR--YGDVSPFLDVYSFGVVLFEIISAQEAIVRTQSG------ILSNKDEQKG-----LATLFEDVLQDDTN
..    ....     ...||  || ||. |   |  .. .||||||.|| |... . | .  ..       ....  |. |     . ||   |  |   
ASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWA

GKERL---RDLMDPRLGDNYPLEAAWSLAKLAGACTKENPELRPNMRTVVVAL
   |.    .. |.| ..  | . . ... .|. |. .   .|. |. |.  |
APRRMQIYEKFIDHRMPP-CPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAK-Un_cj.AA TKL-Unique 499-640 31 1.3e-34 119.53 In-house 59-223 (290) Show / Hide 
Range on Protein: 499-640
Range on HMM: 59-223/290
Sequence Identity: 31% (53 aa)

VQLIGYCT----VES-LFLVYEFVDNGTLAQHLHS--------ATRPPLSWSSRIQIAMDAARGLEYIHEHTKPTYIHRDIKSTNILIDKN-----LHAK
|...|||.     .. ...| |... |.|  .||         .   .|... |...| |.|.|..|.|   .|  ||||.||.|.|.| |     . .|
VHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIK

VADFGLSKLTETGMTSISLTQ----PTRLVGTFGYMSPEYARY--GDVSPFLDVYSFGVVLFEIIS
..||||||.  . ..... .      .  .|.| .|.||  |    . |   ||||||.|| ||..
ICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIAT
Kinase IRAK-Un_cj.AA MLK 499-643 28 2.9e-30 102.26 In-house 72-234 (291) Show / Hide 
Range on Protein: 499-643
Range on HMM: 72-234/291
Sequence Identity: 28% (49 aa)

VQLIGYCTVE-S-LFLVYEFVDNGTLAQHLHSAT-RPP-----------LSWSSRIQIAMDAARGLEYIHEHTKPTYIHRDIKSTNILID------KNLH
.|. | |. . . ...| |....| |.  ||.|.  .             . .. ...|.. |||..| |.. ....||||.|| |||||      ....
IQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGT

AKVADFGLSK-LTET-G-MTSISLTQPTRLVGTFGYMSPEY---ARYGDVSPFLDVYSFGVVLFEIISAQE
.|..|||.|. ....   |.|          ||. .|.||    .| . .|   ||.|.|||| |... ..
LKICDFGTSRDWHQMCTNMMS--------NAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREV
Kinase IRAK-Un_cj.AA Dicty5 510-644 31 7.6e-28 92.91 In-house 74-202 (260) Show / Hide 
Range on Protein: 510-644
Range on HMM: 74-202/260
Sequence Identity: 31% (44 aa)

LFLVYEFVDNGTLAQHLHSATR---PPLSWSSRIQIAMDAARGLEYIHEHTKPTYIHRDIKSTNILIDKNLHAKVADFGLSK--LTETGMTSISLTQPTR
.| | |.. ||.|   |    .    |...  .. .|.|.|......|       ||||.|| |.|| .|. .|. ||| |       .||         
PFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSM---NIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMT---------

L-VGTFGYMSPEYARYGDVSPFLDVYSFGVVLFEIISAQEA
. |||  .|..|           ||||||.||.|..   |.
MHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEP
Kinase IRAK-Un_cj.AA LRRK 499-640 32 8.6e-27 91.8 In-house 120-277 (351) Show / Hide 
Range on Protein: 499-640
Range on HMM: 120-277/351
Sequence Identity: 32% (54 aa)

VQLIGYCTVESLFLVYEFVDNGTLAQHLHSATRPP-------LSWSSRIQIAMDAARGLEYIHEHTKPTYIHRDIKSTNILI---D---------KNLHA
|.|.|.|  . | .| |....|.| ..||.  . .       .||. ...||.. |.|.|| | |. |  |||| || |||.   .          . .|
VSLKGFCI-HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHN-PPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCA

KVADFGLSK---LTETGMTSISLTQPTRLVGTFGYMSPEYARYG---DVSPFLDVYSFGVVLFEIIS
|.||||.|     . .| ..       ..||..|.|.||  ||.     .   |.||||..|.|...
KIADFGISRMFQCFHMGVAK-------GCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLT
Kinase IRAK-Un_cj.AA Dicty4 499-615 32 9.4e-26 83.01 In-house 61-187 (277) Show / Hide 
Range on Protein: 499-615
Range on HMM: 61-187/277
Sequence Identity: 32% (42 aa)

VQLIGYCTV---ES--LFLVYEFVDNGTLAQHLHS-----ATRPPLSWSSRIQ---IAMDAARGLEYIHEHTKPTYIHRDIKSTNILIDKNLHAKVADFG
... |.||    ..  .  | |..  |.|.  ||.       . .|.|. ...   .| |||||. . |. . |  ||||.|| |.|.|||. .||.|||
CLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCN-PVIIHRDLKSHNLLVDKNWRVKVCDFG

LSKLTETGMTSISLTQ-PTRLVGTFGYMSPE
||..  ..   .....  .  .|| ..|.||
LSQYMKKH---EDHKDNQMTACGTPCWMAPE
TyrKc IRAK-Un_cj.AA TyrKc 427-725 21 1.7e-25 91.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 427-725
Range on HMM: 1-280/280
Sequence Identity: 21% (72 aa)

FNETNKIGQGGYGSVYYGYFRDQKLAVKRMNMQATKEFLSELKILSRV--HHSNLVFSQALYFQLTPTIIFLLQVQLIGYCTV--------ESLFLVYEF
     |.| | .| || |  . .. ||| ..  | ..|..|..|....  || |.                   |.|.|.||         | |..| |.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNI-------------------VRLYGVCTQQGRNFMYIEPLMIVMEY

VDNGTLAQHLHSATRPPLSWSSRIQIAMDAARGLEYIHEHTKPTYIHRDIKSTNILIDKNLHAKVADFGLSKLTETG--------MTSISLTQPTRLVGT
...| | ..|..  .  |...  .... ..|.| ||.|..    .||||.   |.|...|...|..|||||.  . .        . . . .. .. .  
MPHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

FGYMSPEYARYGDVSPFLDVYSFGVVLFEI---------------ISAQEAIVRTQSG-ILSNKDE----QKGLATLFEDVLQDDTNGKERLRDLMDPRL
   |.||  .||  ..  ||.||||...||               .|.||.| . ..|  .   ..                                  
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------

GDNYPLEAAWSLAKLAGACTKENPELRPNMRTVVVAL
   .  ..   . ..   | .|.|| ||......  .
---F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
S_TKc IRAK-Un_cj.AA S_TKc 427-729 19 3.2e-25 91.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 427-729
Range on HMM: 1-231/231
Sequence Identity: 19% (63 aa)

FNETNKIGQGGYGSVYYGYFRD--QKLAVKRMNMQATKEFLSELKILSRVHHSNLVFSQALYFQLTPTIIFLLQVQLIGYCTVESLFLVYEFVDN--GTL
.   .|||.|..|.|| .. ..  .. |.|...    . ...|..||.. || |.|     .                     ..|..| |..|.  |.|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-------------------DHLYMVMEYCDGDLGDL

AQHLHSATRPP----LSWSSRIQIAMDAARGLEYIHEHTKPTYIHRDIKSTNILIDKNLHAKVADFGLSKLTETGMTSISLTQPTRLVGTFGYMSPEYAR
 .....  |..    ..      ..   ...|||.|.| .   ||||.|  |||.|.  | |..||||...             | ..||  ||.||   
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL-

YGDVSP-FLDVYSFGVVLFEIISAQEAIVRTQSGILSNKDEQKGLATLFEDVLQDDTNGKERLRDLMDPRLGDNYPLEAAWSLAK-LAGACTKENPELRP
    ..   |..|.|..|.| ..  .   .              ....|. ..                            . || .   | . .|| ||
--GYGKCKCDWWSCGCILYEMLC-GYPPFP-------------QMQMMFKKIG---------------------------SPEAKDFIRKCLQKDPEKRP

NMRTVVV-----ALMTLV
    .       ...  .
TA-EALQDEWDIKCHPWF
Kinase IRAK-Un_cj.AA Pkinase 499-640 29 1.7e-24 87.69 Pfam 63-207 (293) Show / Hide 
Range on Protein: 499-640
Range on HMM: 63-207/293
Sequence Identity: 29% (45 aa)

VQLIGYC-TVESLFLVYEFVDNG----TLAQHLHSATRPPL--SWSSRIQIAMDAARGLEYIHEHTKPTYIHRDIKSTNILIDKNLHA----KVADFGLS
|.|.... .  .. .| |....|     |. ...   . ..  |.   . ..   .|||||.|..     ||||.|. |||||.| |     |..||||.
VRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLA

KLTETGMTSISLTQPTRLVGTFGYMSPEYAR-YGDVSPFLDVYSFGVVLFEIIS
|. .      . . .| ..|| .||.||  | . . .|  |..|.|..|.| ..
KQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC
Kinase IRAK-Un_cj.AA TK 499-640 15 5.2e-24 76.72 In-house 106-389 (486) Show / Hide 
Range on Protein: 499-640
Range on HMM: 106-389/486
Sequence Identity: 15% (44 aa)

VQLIGYCTVES-------------LFLVYEFVDNGT----LAQHLHSATRP-------------------------------------------------
|.|.|.|| .              . .| |....|     | ..|..  ..                                                 
VRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLI

-------------------------PLSWSSRIQIAMDAARGLEYIHEH----TKPTYIHRDIKSTNILIDKNLH-----------AKVADFGLSKLTET
                         .|.   .. .....|.|.||.|..      . ..|||.   |.|...|..           .|.||||||. .. 
KDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGS-

GMTSISLTQ--PTRLVGTFG----------------------------YMSPEYAR---------YGDVSPFLDVYSFGVVLFEIIS
|. .  . .    . ... |                            .|.||  .         ||  ..  ||.||||...|| .
GVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_cj.AA TK-Unique 499-640 23 1.1e-21 71.69 In-house 67-234 (294) Show / Hide 
Range on Protein: 499-640
Range on HMM: 67-234/294
Sequence Identity: 23% (40 aa)

VQLIGYCT-V-ESLFLVYEFVDNGTLAQHLHSATRP------------------------PLSWSSRIQIAMDAARGLEYIHE--HTKPTYIHRDIKSTN
||..|.||   |. ....|.. .|.|  .|..  ..                        |.|  . ...| . |.|.||...  .     .|||. . |
VQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI---VHRDLCARN

ILIDKNLHAKVADFGLSKLTETGMTSISLTQPTRLVGTFGYMSPEYAR--YGDV-SPFLDVYSFGVVLFEIIS
.|.  .. .|..|||... ..|.   .. ..  |.     .|.||. .  .|   ..  ||.||||...|| .
VLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP--IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_cj.AA Pkinase_Tyr 499-589 30 1.4e-21 73.71 Pfam 67-160 (270) Show / Hide 
Range on Protein: 499-589
Range on HMM: 67-160/270
Sequence Identity: 30% (30 aa)

VQLIGYCT-V-ES--LFLVYEFVDNGTLAQHLHSA--TRPPLSWSSRIQIAMDAARGLEYIHEHTKPTYIHRDIKSTNILIDKNLHAKVADFGLSKL
|.|.| ||   |.  ...| |.. .| |  .|..    ..||. .  .|.... |.|.|| ...    .||||.   |.|...|...|..||||...
VRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARD
Kinase IRAK-Un_cj.AA STE 499-639 23 7.9e-20 66.78 In-house 93-262 (359) Show / Hide 
Range on Protein: 499-639
Range on HMM: 93-262/359
Sequence Identity: 23% (42 aa)

VQLIGYCTVE--------SLFLVYEFVDNGTLAQHLHS--ATRPPLS----------WSSRIQIAMDAARG-LEYIHEHTKPTYIHRDIKSTNILIDKNL
|. .|.. .|        .|... |..|.|.| . ...   .  ||.           |  . |. .  .| |.|.|.|    .||||||. |||.    
VKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----

HAKVADFGLSK-LTETGMTSISLT------------QPTRLVGTFGYMSPEYARY------GDVSPFLDVYSFGVVLFEII
 .| .|||... ||...  . . .            . . .|||  .|.||  .       .. .   |..|.| .. | .
-VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase IRAK-Un_cj.AA IRAK 427-480 33 3.8e-12 39.48 In-house 1-66 (317) Show / Hide 
Range on Protein: 427-480
Range on HMM: 1-66/317
Sequence Identity: 33% (22 aa)

FNETNKIGQGGYGSVYYGYFRDQK--LAVKRMNMQAT-------KEFLS---ELKILSRVHHSNLV
|.. |.||.||.| || | .. .    |||.    |        ..|..   |||...| .| |.|
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIV
Kinase IRAK-Un_cj.AA TKL-Unique 430-480 36 5e-11 35.31 In-house 2-59 (290) Show / Hide 
Range on Protein: 430-480
Range on HMM: 2-59/290
Sequence Identity: 36% (21 aa)

TNKIGQGGYGSVYYGYFRDQKLAVKRMNM------QATKEFLSELKILSRVH-HSNLV
 ||||.||||.|| | .|  . |.|. .       . ..|| .|...... | | |.|
WNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIV
Kinase IRAK-Un_cj.AA STE 427-480 19 9.2e-11 34.35 In-house 1-93 (359) Show / Hide 
Range on Protein: 427-480
Range on HMM: 1-93/359
Sequence Identity: 19% (18 aa)

FNETNKIGQGGYGSVYYGYFRDQK-----------------LAVKRMNMQATK--------------------EFLSELKILSRVH--HSNLV
.    |||.|..|.||... ...                   |.|.||..  .                    ..| |.||... .  | | |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIV
Kinase IRAK-Un_cj.AA TKL 433-480 20 1.6e-10 34.08 In-house 1-88 (364) Show / Hide 
Range on Protein: 433-480
Range on HMM: 1-88/364
Sequence Identity: 20% (18 aa)

IGQGGYGSVYYGYFRD----------QKLAVKRMNMQ------------------------------ATKEFLSELKILSRVHHSNLV
||.||.| || |..|           .  |||.....                              . ...  |....|| .| |.|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIV
Kinase IRAK-Un_cj.AA MLK 427-481 22 9.7e-10 30.09 In-house 1-74 (291) Show / Hide 
Range on Protein: 427-481
Range on HMM: 1-74/291
Sequence Identity: 22% (17 aa)

FNETNKIGQGGYGSVYYGYFRDQK-----LAVKRMNMQA---------TKEFLSELKILSRVHHSN-----LVF
...  .|| |..|.|. |..| .      .|||| .  .          ..|  | ..|... | |      .|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQF
Kinase IRAK-Un_cj.AA Pkinase_Tyr 427-480 29 5.8e-09 30.98 Pfam 1-67 (270) Show / Hide 
Range on Protein: 427-480
Range on HMM: 1-67/270
Sequence Identity: 29% (20 aa)

FNETNKIGQGGYGSVYYGYFR------DQKLAVKRMNMQATKE------FLSELKILSRV-HHSNLV
     |.|.| .|.|| |. .      ... ||| .. .|..|      |..|.||..   || |.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIV
Kinase IRAK-Un_cj.AA Dicty4 427-469 32 2.6e-07 20.62 In-house 1-46 (277) Show / Hide 
Range on Protein: 427-469
Range on HMM: 1-46/277
Sequence Identity: 32% (15 aa)

FNETNKIGQGGYGSVYYGYFRDQKLAVKRM---NMQATKEFLSELK
 | ...||.|..|.|| |  | .. ||| .   |  .  ..|.|..
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFR
Kinase IRAK-Un_cj.AA LRRK 427-480 17 5e-06 17.23 In-house 1-120 (351) Show / Hide 
Range on Protein: 427-480
Range on HMM: 1-120/351
Sequence Identity: 17% (21 aa)

FNETNKIGQGGYG-SVYYGYFRD----------------------------QKLAVKRMNM-------------------------------------QA
. . ..||.||.| .|| . .|.                            |. |.| .|.                                      |
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

TKEFLSELKILSRVHHSNLV
  ||  |. |.|. .|.|.|
FREFRHEVWIMSHLNHPNIV
Kinase IRAK-Un_cj.AA TK 427-480 17 1.5e-05 13.75 In-house 1-106 (486) Show / Hide 
Range on Protein: 427-480
Range on HMM: 1-106/486
Sequence Identity: 17% (19 aa)

FNETNKIGQGGYG---SVYYGYFRD---------------------------QKLAVKRMN----MQATKEFL----------------SELKILS--RV
    .|.|.| .|    || |  |.                           .. ||| .     |... .|.                .|.|...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHSNLV
|| |.|
HHPNIV
Kinase IRAK-Un_cj.AA Pkinase 427-480 28 4.3e-05 19.1 Pfam 1-63 (293) Show / Hide 
Range on Protein: 427-480
Range on HMM: 1-63/293
Sequence Identity: 28% (18 aa)

FNETNKIGQGGYGSVYYGYFRDQK--LAVKRMNMQATKEFL-------SELKILSRVHHSNLV
.    |||.|..|.|| .. ..     |||... . .|.         ||..|. |..| | |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIV
Kinase IRAK-Un_cj.AA TK-Unique 427-480 25 6.8e-05 12.94 In-house 1-67 (294) Show / Hide 
Range on Protein: 427-480
Range on HMM: 1-67/294
Sequence Identity: 25% (17 aa)

FNETNKIGQGGYGSVYYGYFR--------DQKLAVKRMNMQATKE----FLSELKILSRVH-HSNLV
..  ..||.| .| |. | ..        ... |||  .  ||..    ||.|..... .  | |.|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIV
Kinase IRAK-Un_cj.AA TK 707-725 31 0.001716 6.72 In-house 468-486 (486) Show / Hide 
Range on Protein: 707-725
Range on HMM: 468-486/486
Sequence Identity: 31% (6 aa)

CTKENPELRPNMRTVVVAL
| ...|| ||...... .|
CWHYDPEDRPTFSQLHEQL
Kinase IRAK-Un_cj.AA Dicty4 627-638 83 0.002186 7.35 In-house 199-210 (277) Show / Hide 
Range on Protein: 627-638
Range on HMM: 199-210/277
Sequence Identity: 83% (10 aa)

DVYSFGVVLFEI
|||||| ||.||
DVYSFGIVLWEI
Kinase IRAK-Un_cj.AA Pkinase_Tyr 627-640 57 0.00803 10.18 Pfam 196-209 (270) Show / Hide 
Range on Protein: 627-640
Range on HMM: 196-209/270
Sequence Identity: 57% (8 aa)

DVYSFGVVLFEIIS
||.||||...||..
DVWSFGVLMWEIFT
Kinase IRAK-Un_cj.AA TK-Unique 707-725 36 0.010424 5.31 In-house 276-294 (294) Show / Hide 
Range on Protein: 707-725
Range on HMM: 276-294/294
Sequence Identity: 36% (7 aa)

CTKENPELRPNMRTVVVAL
|....|| ||. |...  |
CWQWEPEERPSFRQIKHRL
Kinase IRAK-Un_cj.AA MLK 699-725 33 0.035411 3.51 In-house 265-291 (291) Show / Hide 
Range on Protein: 699-725
Range on HMM: 265-291/291
Sequence Identity: 33% (9 aa)

SLAKLAGACTKENPELRPNMRTVVVAL
...||   | ...|. ||..| .|  |
HWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase IRAK-Un_cj.AA TKL-Unique 706-725 25 0.099136 2.1 In-house 271-290 (290) Show / Hide 
Range on Protein: 706-725
Range on HMM: 271-290/290
Sequence Identity: 25% (5 aa)

ACTKENPELRPNMRTVVVAL
.| . .|. ||.  ...  |
QCWHHDPSQRPSFDEIIHRL
Kinase IRAK-Un_cj.AA LRRK 707-727 28 0.152344 1.21 In-house 331-351 (351) Show / Hide 
Range on Protein: 707-727
Range on HMM: 331-351/351
Sequence Identity: 28% (6 aa)

CTKENPELRPNMRTVVVALMT
| ...|. || . ..|  | .
CWQHDPKKRPHFSQIVKRLSQ
Kinase IRAK-Un_cj.AA Pkinase_Tyr 709-725 29 2.005707 2.06 Pfam 254-270 (270) Show / Hide 
Range on Protein: 709-725
Range on HMM: 254-270/270
Sequence Identity: 29% (5 aa)

KENPELRPNMRTVVVAL
...|| || .. ..  |
HYDPEDRPTFSEIHEQL