Gene IRAK-Un_v-2 (S.moellendorffii)

IRAK-Un_v-2

Species: S.moellendorffii
Alias: IRAK-Un_v-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_v-2.AA Protein None 357 None Fasta, JSON
IRAK-Un_v-2.NA RNA None 1074 None Fasta, JSON
IRAK-Un_v-2.kin_dom Protein Kinase Domain None 195 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_v-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_v-2.AA TKL 41-308 22 5.4e-60 205.62 In-house 1-364 (364) Show / Hide 
Range on Protein: 41-308
Range on HMM: 1-364/364
Sequence Identity: 22% (86 aa)

LGHGGHGTVYKGKLPD---------GRDVAVKRINH--ISSHGI-------------------------EQVLNEVKVLLSVSHPNLVQLLGCCLEVYD-
.| || |.|||||.           |.|||||...    ... .                         ..  .|...... .|||.||..|.|..  . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PLLVYEFVPNGTLAEHLQRERGDGLDWFTRVAIAAEAAQGIAYLHSRS------PPIYHRDVKSTNILLDGEFN--------------
            . .|.|..|.|.| ..|.        |  |. .| ..|.|..||||.       ||| ||| || |||.|  ..              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

TKVGDFGLSRTALTEASHVSTA------------------PQGTPGYVDPDY----------------HQSFQLSDKSDVYSFGVVLVEMITSMKVVDFT
 |..||||||.  .. .   |.                  . |||..  |                   ..|. | |.||||||.|| |..|  . . . 
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYD

RDKREVNLAALAVGKIATDCLDEIIDPAL------MIQACRNPVVRC--MIQRMAELAFRCLAHEKDARPSMAEVFDEV
 . ... .. . .  ..  . |.   | .      .    . . . |  . ..|..|. .| .|. ..|||. |. .. 
YPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHH---K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-Un_v-2.AA IRAK 35-308 29 1.5e-53 184.23 In-house 1-317 (317) Show / Hide 
Range on Protein: 35-308
Range on HMM: 1-317/317
Sequence Identity: 29% (96 aa)

FSPAQMLGHGGHGTVYKGKLPDGRD--VAVKRI---NHISSHGIEQVLNE----VKVLLSVSHPNLVQLLGCCLEVYDPLLVYEFVPNGTLAEHLQRERG
|...  .| || |.||.|.. .. .  .|||..   . .|  ...| ..     .||...  |||.| |.| |.|  .. |||.. |||.|   |.   |
FHKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDG

-DG---LDWFTRVAIAAEAAQGIAYLHSRSP--PIYHRDVKSTNILLDGEFNTKVGDFGLSR------TALTEAS---HVSTAPQGTPGYVDPDYHQ--S
 .    | | .|. |.  .| || .||. .|  || |.|.|| |||||  |. | .|||| |        .   .   ..|.  .||  |  |..    .
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHV-RGTTWYMPPEFIRDPQ

FQLSDKSDVYSFGVVLVEMITSMKVVDFTRDKREVNLAALAVGKIATDCL---------------DEIIDPALM------IQACRNPVVRCMIQRMAELA
 ||. |.||||||.|| | .|  ..|.   | .|. .  . .  |.  .                |    |  |      |    .|... | . |. .|
GQLTKKTDVYSFGIVLLEVLTGCRAVY--DDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQCA

FRCLAHEKDARPSMAEVFDEV
 .|..| .  |..||.|  . 
CCCGHHRANRRCDMAWVMQQL
Kinase IRAK-Un_v-2.AA TKL-Unique 37-231 33 1.1e-42 148.11 In-house 1-225 (290) Show / Hide 
Range on Protein: 37-231
Range on HMM: 1-225/290
Sequence Identity: 33% (76 aa)

PAQMLGHGGHGTVYKGKLPDGRDVAVKRINH---ISSHGIEQVLNEVKVLLSVS-HPNLVQLLGCCL--EVYDP--LLVYEFVPNGTLAEHLQR------
.   .| || |.||||| . | .||.|...    .|.  ..   |||...     |||.|.. | |    || |   .| |..| |.| ..|..      
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--ERGDGLDWFTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNILLDGE-----FNTKVGDFGLSRTALTE-ASHVS-------TAPQGTPGYVDPDYHQ
  ..   |..  || .|  .|||  |||...|||.||| ||.|.|.| .     .| |. |||||... .. .. ..       . ..|.. .. |    
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

S--FQLSDKSDVYSFGVVLVEMITSM
.  .| | ||||||||.|| |..|..
MNFCQYSEKSDVYSFGIVLWEIATRK
Kinase IRAK-Un_v-2.AA Pkinase 35-229 25 3.6e-42 150.18 Pfam 1-207 (293) Show / Hide 
Range on Protein: 35-229
Range on HMM: 1-207/293
Sequence Identity: 25% (54 aa)

FSPAQMLGHGGHGTVYKGKLPDGRD-VAVKRINHISSHGIEQVLN----EVKVLLSVSHPNLVQLLGCCLEVYDPLLVYEFVPNG----TLAEHLQRERG
.   . .| |. |.|||..  . .. ||||.|.  . .  ... .    |........||| |.|.... .  .. .| |....|     |.......|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DGL--DWFTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNILLDGEFNT----KVGDFGLSRTA-LTEASHVSTAPQGTPGYVDPDYHQ-SFQLSDKSDV
 ..  .. .   .. . ..|..|.||.   | |||.|. |||.| . ..    |..||||.. . .   |   | . |||.|. |  .. .   . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGVVLVEMIT
.|.|..| ||..
WSCGCILYEMLC
Kinase IRAK-Un_v-2.AA Dicty4 35-229 32 1e-39 130.21 In-house 1-212 (277) Show / Hide 
Range on Protein: 35-229
Range on HMM: 1-212/277
Sequence Identity: 32% (69 aa)

FSPAQMLGHGGHGTVYKGKLPDGRDVAVKRI---NH-ISSHGIEQVLNEVKVLLSVSHPNLVQLLGCCL----EVYDPLLVYEFVPNGTLAEHLQR----
    | .| |. |.||||.   | .||||     |   ..  ..  ..||. . . .|||.....| |.    .  ... | |..| |.|.. |      
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

-ERGDGLDWFTRVA---IAAEAAQGIAYLHSRSPPIYHRDVKSTNILLDGEFNTKVGDFGLSRTALTEASHVS--TAPQGTPGYVDPDYHQSFQLSDKSD
    . ||| .. .   .|  ||.|...||.. | | ||| || |.| |  .. ||.|||||.   .. .|    ... |||... |   ..     |.|
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSFGVVLVEMIT
||||| || |. |
VYSFGIVLWEILT
Kinase IRAK-Un_v-2.AA S_TKc 35-316 22 1.5e-37 132.01 SMART 1-231 (231) Show / Hide 
Range on Protein: 35-316
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

FSPAQMLGHGGHGTVYKGKLPD-GRDVAVKRINHISSHGIEQVLNEVKVLLSVSHPNLVQLLGCCLEVYDPLLVYEFVPN--GTLAEHLQRERGDG----
.   . .|.|. |.|||..  . || ||.|.|.       |....|...| .  |||.|.|.... .  .  .| |....  |.| ..... .. |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWFTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNILLDGEFNTKVGDFGLSRTALTEASHVSTAPQGTPGYVDPDYHQSFQLSD-KSDVYSFGVVLVE
..  .   .... .....|.||.   | |||.|  |||||   . |..||||.|          |   ||| |. |      . .  |.|..|.|..| |
FPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MITSMKVVDFTRDKREVNLAALAVGKIATDCLDEIIDPALMIQACRNPVVRCMIQRMAELAFRCLAHEKDARPSMAEVFD-EVEGIRHSCL
|..     .                           ....|.. ..        . . ..  .||  . . ||.  |..  |..   |  .
MLCGYPPFP---------------------------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-Un_v-2.AA Dicty4-Unclassified 38-229 34 4.1e-37 124.63 In-house 4-203 (263) Show / Hide 
Range on Protein: 38-229
Range on HMM: 4-203/263
Sequence Identity: 34% (72 aa)

AQMLGHGGHGTVYKGKLPDGRDVAVKRINHIS-SHG---IEQVLNEVKVLLSVSHPNLVQLLGCCLEVYDP-------LLVYEFVPNGTLAEHLQ-----
 | .| |    |.||    |.||||| .|  . .     |.  . || .| |..|||||.. | |.    |         | || . |.| |        
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN---PRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

RERGDGLDWFTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNILLDGEFNTKVGDFGLSRTALTEASHVSTAPQGTPGYVDPDYHQSFQLSDKSDVYSFG
...   ||    ...| . |||...||.|   . |||.|| |||.|  || |..|||.||   ..     |.  |||    |          ||||||..
QQQPIKLDDTLIIKYAFDIAQGMQHLHTRN--FIHRDIKSSNILMDKHFNIKIADFGISR--VIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

VVLVEMIT
..| |..|
MMLYELAT
Kinase IRAK-Un_v-2.AA LRRK 35-229 25 2.9e-36 125.77 In-house 1-277 (351) Show / Hide 
Range on Protein: 35-229
Range on HMM: 1-277/351
Sequence Identity: 25% (71 aa)

FSPAQMLGHGGHG-TVYKGKLPD---------------------------GRDVAVKRINHI----------------------------------SSHG
.   ...| || | .||..|. .                           . .||.| .| .                                  ... 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

IEQVLNEVKVLLSVSHPNLVQLLGCCLEVYDPL-LVYEFVPNGTLAEHLQRERGDG-------LDWFTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNI
     .|| .. .  |||.|.|.| |..   || .| |..|.|.| ..|. .. ||       ..| ..  || . | |..||||..||| ||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH---PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNI

LL---D---------GEFNTKVGDFGLSR--TALTEASHVSTAPQGTPGYVDPDYHQSF---QLSDKSDVYSFGVVLVEMIT
||   .          . . |..|||.||  ......  |     |.||.. |   .     . ..|.|.||||..| | .|
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMG--VAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLT
Kinase IRAK-Un_v-2.AA TK 35-229 15 2.8e-34 111.77 In-house 1-389 (486) Show / Hide 
Range on Protein: 35-229
Range on HMM: 1-389/486
Sequence Identity: 15% (61 aa)

FSPAQMLGHGGHG---TVYKGKLPDGR--------------------------DVAVKRINHISSHGIEQVLN-----------------EVKVLLS--V
    . ||.|  |   .||||.. ...                          .|||| .   ...  |. .                  | |....   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPNLVQLLGCCLEV------------YDPLLVYEFVPNGT----LAEHLQRERGDG-------------------------------------------
 |||.|.|.|.|...              ...| |..|.|     | ..|.. |...                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWFTRVAIAAEAAQGIAYLHSRSP----PIYHRDVKSTNILLDGEFN-----------TKVGDFG---
                               |.  ... ... .|.| .||||.       . |||.   |.|.. . .            |..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRTALTEASHVSTAPQGTP-GYVD-------PDYHQS---------------FQ------------LSDKSDVYSFGVVLVEMIT
     |.|    .   ... ..||. .. .        ||  .               ..             . ||||.||||.. |. |
QGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_v-2.AA MLK 35-229 29 7.2e-33 111.4 In-house 1-231 (291) Show / Hide 
Range on Protein: 35-229
Range on HMM: 1-231/291
Sequence Identity: 29% (69 aa)

FSPAQMLGHGGHGTVYKGKLPDGRD-----VAVKRINH------ISSHGIEQVLNEVKVLLSVSHPN----LVQLLGCCLEV-YDPLLVYEFVPNGTLAE
.   . .|.|. | |.||.   ..|     |||||...      ...  ....  |.. |  .||||     .|..|.||.  .. ..| |....| |..
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HL--QRERGD----------GLDWFTRVAIAAEAAQGIAYLHSRSP-PIYHRDVKSTNILLD------GEFNTKVGDFGLSRTALTEASHV---STAPQG
 |  .|  ..            |    . .|   |.|..||||  | || ||| || |||.|      .. . |. |||.||    . ..     .  .|
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR----DWHQMCTNMMSNAG

TPGYVDPDY---HQSFQLSDKSDVYSFGVVLVEMIT
|. .  |      .. . | |.||.|.|||| ||.|
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT
Kinase IRAK-Un_v-2.AA Pkinase_Tyr 39-182 29 3.4e-32 109.68 Pfam 5-160 (270) Show / Hide 
Range on Protein: 39-182
Range on HMM: 5-160/270
Sequence Identity: 29% (47 aa)

QMLGHGGHGTVYKGKLP-----DGRDVAVKRINHISSHG---IEQVLNEVKVLLSV-SHPNLVQLLGCCLEVYDP---LLVYEFVPNGTLAEHLQRE--R
..||.|  |.||||..      .. .|||| ... ..|    .|  ..|.|.. .  .|||.|.|.|.|..  .|   ..| |..|.| | ..|..    
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHRED

GDGLDWFTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNILLDGEFNTKVGDFGLSRT
.. |.  . . .... |.| .||.|.   . |||.   |.|.. ..  |..||||.|.
KQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARD
Kinase IRAK-Un_v-2.AA RIPK 41-229 27 1.9e-30 100.93 In-house 1-223 (290) Show / Hide 
Range on Protein: 41-229
Range on HMM: 1-223/290
Sequence Identity: 27% (61 aa)

LGHGGHGTVYKGKLPDGRDVAVKRI---NHISSH----GIEQVLNEVKVLLSVSHPNLVQLLGCCLEVYD------PLLVYEFVPNGTLAEHLQRERG--
.| || |.|.|    . .|...| .    |.  |      .... |.| . .  . . |...| | .. .      . .| |. .|| |.. |...    
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-DGLDWFTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNILLDGEFNTKVGDFGLSRTALTEASHVST-------------APQ-GTPGYVDPDYHQSFQ
   . |  |  .  | . |  ||||  ||| ||| |  |||.|..|. |. ||||.  .  . ||. .             ... ||  | .|      .
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLA--TWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

LSD------KSDVYSFGVVLVEMIT
 .       |.|||||..|. |  |
KKPIKVVTPKYDVYSFAIVMWEVLT
Kinase IRAK-Un_v-2.AA LISK 40-183 33 1.9e-26 82.74 In-house 1-155 (296) Show / Hide 
Range on Protein: 40-183
Range on HMM: 1-155/296
Sequence Identity: 33% (52 aa)

MLGHGGHGTVYKGKLP-DGRDVAVKRINH-----ISSHGIEQVLNEVKVLLSVSHPNLVQLLGCCLE-VYDPLLVYEFVPNGTLAEHLQRE--RGDGLDW
 .| |. | |||| .  .|...|.| |       .    .  .| ||... . .||| ||  | | .      .| |..  |.| . | ..  .   | |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

FTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNILLD----GEFNTKVGDFGLSRTA
. || ||   |.| .||||.   | ||| ||.|.|..    . .. ||.|||. |..
PQRVKIALDIACGMSYLHSMN--IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMM
Kinase IRAK-Un_v-2.AA TyrKc 35-311 22 5.4e-23 83.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 35-311
Range on HMM: 1-280/280
Sequence Identity: 22% (70 aa)

FSPAQMLGHGGHGTVYKGKLPDGRDVAVKRINHISSHGIEQVLNEVKVLLSV--SHPNLVQLLGCCLEV-------YDPLLVYEFVPNGTLAEHLQRERG
 .  ..||.|  |.||||..   ..|||| ... .   .|  ..| ... ..  .|||.|.|.|.|..          ...| |..|.| | ..|.. |.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

DGLDWFTRVAIAAEAAQGIAYLHSRSPPIYHRDVKSTNILLDGEFNTKVGDFGLSRTALTE----ASHVSTAPQ---GTPG-----------YVDPDYHQ
. | . . . ..  .|.| .||||.  .. |||    |.|.. ..  |..||||||    .    .|.    ..   |. .                  .
K-LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI------N

SFQLSDKSDVYSFGVVLVEMITSMKVVDFT-----RDKREVNLAALAVG----KIATDCLDEIIDPALMIQACRNPVVRCMIQRMAELAFRCLAHEKDAR
    . ||||.||||.. |. |  .           . .|| .. .  |    . . |.  . .               |. . | ..  .| ... . |
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV-IEYVKQGYRMPQPPNDY--P-MS-----------F-VCCPDEMYQIMKQCWHEDPEDR

PSMAEVFDEVEGI
|...|.   .| .
PTFSEI---HECF
Kinase IRAK-Un_v-2.AA LISK 212-233 50 4.3e-07 18.88 In-house 217-238 (296) Show / Hide 
Range on Protein: 212-233
Range on HMM: 217-238/296
Sequence Identity: 50% (11 aa)

SDKSDVYSFGVVLVEMITSMKV
....||.|||.||.|.|| .|.
DESCDVFSFGIVLCEIITRVKA
Kinase IRAK-Un_v-2.AA Pkinase_Tyr 214-229 62 0.004097 11.17 Pfam 194-209 (270) Show / Hide 
Range on Protein: 214-229
Range on HMM: 194-209/270
Sequence Identity: 62% (10 aa)

KSDVYSFGVVLVEMIT
||||.||||.. |..|
KSDVWSFGVLMWEIFT
Kinase IRAK-Un_v-2.AA TK 277-308 15 0.026224 2.68 In-house 455-486 (486) Show / Hide 
Range on Protein: 277-308
Range on HMM: 455-486/486
Sequence Identity: 15% (5 aa)

RCMIQRMAELAFRCLAHEKDARPSMAEVFDEV
.|. . ...|  .| ... . ||..... .. 
HCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL