IRAK-Un_dn

Species: S.moellendorffii
Alias: IRAK-Un_dn
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_dn.AA Protein None 363 None Fasta, JSON
IRAK-Un_dn.NA RNA None 1092 None Fasta, JSON
IRAK-Un_dn.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_dn.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_dn.AA IRAK 57-257 35 4.2e-61 209.3 In-house 1-225 (317) Show / Hide
Range on Protein: 57-257
Range on HMM: 1-225/317
Sequence Identity: 35% (80 aa)

FSEENQLGQGGFGVVYKANLKDGT-QVAVKKL----SLHSKQGKQEFVN---ELNIITGIRHRNLAMLHGYCVEANERLLVYEFLENGSLD---SALFQS
|...| .|.||||.||.. .|  |  .|||||    ..  .. .|.|     || . . .|| |.  | ||| |  .  |||... ||||    ... ..
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

SS--ALNWQSRFQITIGIARGLAYLHEES-HFQIIHRDIKASNVLLDAKLQPKISDFGLSKL-----FDLDGKH---VVSKVAGTFGYMAPEYAV--HRR
 .  .| |. |. | .|.|.|. .||. .    |||.||| .|.|||. ..|||.||||          ....     .|.| ||  ||.||.     ..
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LSPKADVFSFGVPVLVILSGRKCVD
|..| ||.|||. .| .|.|.. |.
LTKKTDVYSFGIVLLEVLTGCRAVY

Kinase IRAK-Un_dn.AA TKL 63-244 23 3e-57 196.53 In-house 1-277 (364) Show / Hide
Range on Protein: 63-244
Range on HMM: 1-277/364
Sequence Identity: 23% (66 aa)

LGQGGFGVVYKANLKD---------GTQVAVKKLSLHSKQGK---------------------------QEFVNELNIITGIRHRNLAMLHGYCVEANE-
.|.||||.|||....          |. |||||.. |. . .                           .....|....  .|| |.  . ||| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEFLENGS-LDSALFQSSSALNWQSRFQITIGIARGLAYLHEESH-----FQIIHRDIKASNVLLDAKLQ--------------
              .|.|. ..|| |.  .        |. |... ..||||..||| .        .|||||.| .|.|.| ...              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

PKISDFGLSKLFDL------------------DGKHVVSKVAGTFGYMAPEY---------AV-------HRRLSPKADVFSFGV
.||.|||||. ..                   ...   ... ||...||||          .|       ..  |.|.||.|||.
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGI

Kinase IRAK-Un_dn.AA Pkinase 57-244 28 3.9e-42 150.05 Pfam 1-200 (293) Show / Hide
Range on Protein: 57-244
Range on HMM: 1-200/293
Sequence Identity: 28% (58 aa)

FSEENQLGQGGFGVVYKANLKDGTQ-VAVKKLSLHSKQGKQE--FVN--ELNIITGIRHRNLAMLHGYCVEANERLLVYEFLENG----SLDSALF-QSS
.  . ..|.|.||.|||.  |.  . ||||.......  ...   ..  |. |   ..| |   |.... . ..  .| |..|.|    .| . .  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SAL--NWQSRFQITIGIARGLAYLHEESHFQIIHRDIKASNVLLDAKLQP----KISDFGLSKLFDLDGKHVVSKVAGTFGYMAPEYAV-HRRLSPKADV
 ..   ..    .   |.|||.|.|..    |||||.| .|.|.| . ..    ||.||||.|.||.  ..  . ..|| .|||||    ..  .||.|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSFGV
.|.|.
WSCGC

Kinase IRAK-Un_dn.AA TK 57-244 15 1.4e-41 136.7 In-house 1-382 (486) Show / Hide
Range on Protein: 57-244
Range on HMM: 1-382/486
Sequence Identity: 15% (61 aa)

FSEENQLGQGGFG---VVYKANLKDG--------------------------TQVAVKKLSLHSKQGKQEFVN--------------ELNIITGIR----
   ...||.| ||   .|||. ....                          |.|||| | ... . ..||                |....   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLAMLHGYCVEA------------NERLLVYEFLENGS----LDSALFQSSSA--------------------------------------------
 | |.  |.|.|..                ..| |. ..|.    |.. | ...                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNWQSRFQITIGIARGLAYLHEE--SHF--QIIHRDIKASNVLLDAKLQ-----------PKISDFG--
                               |. . .  .   ||.|..|||.   . |  ...|||. | |.|.. ...            ||.|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSKLFDLDGKHVVSKVAGTFG-------------------------YMAPEYAV---------HRRLSPKADVFSFGV
      |..  . |.  ....  || .                         .||||            ... ..| ||.||||
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGV

Kinase IRAK-Un_dn.AA TKL-Unique 61-244 33 3.9e-41 142.83 In-house 3-216 (290) Show / Hide
Range on Protein: 61-244
Range on HMM: 3-216/290
Sequence Identity: 33% (73 aa)

NQLGQGGFGVVYKANLKDGTQVAVKKLSL---HSKQGKQEFVNELNIITGIR-HRNLAMLHGYCV----EANERLLVYEFLENGSLDSALF---------
| .|.||.|.|||.  . |..||.|....    |.. .||| ||.|..  .. | |.  . |||.     .... .| |... |||.. |          
NKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

QSSSALNWQSRFQITIGIARGLAYLHEESHFQIIHRDIKASNVLLDAK-----LQPKISDFGLSKLFDLDGKHVVS--------KVAGTFGYMAPEYAVH
 ... ||.| | .. | ||.|. ||| ..   |||||.| ||.|.| .     .. ||.||||||. . . |  ..         . |.| .||||    
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--RRLSPKADVFSFGV
     | |.||.|||.
NFCQYSEKSDVYSFGI

Kinase IRAK-Un_dn.AA MLK 57-244 26 2.1e-36 123.81 In-house 1-224 (291) Show / Hide
Range on Protein: 57-244
Range on HMM: 1-224/291
Sequence Identity: 26% (60 aa)

FSEENQLGQGGFGVVYKANLKDGTQ-----VAVKKLS---LHSKQG----KQEFVNELNIITGIRHRN----LAMLHGYCVEA-NERLLVYEFLENGSLD
. ..  .| |.||.|.|.. . ..      ||||.       .|.     ...|  | ..   ..|.|       . | | .  .. ..| |..|.||| 
IQFHEWIGSGSFGKVWKGRWR-NKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

SALFQSSS-------------ALNWQSRFQITIGIARGLAYLHEESHFQIIHRDIKASNVLLDA------KLQPKISDFGLSKLFDLDGKHVVSKVAGTF
. |   .|                 .. ...   .|||..|||..   .|||||.| .|.|.|.      ... ||.|||.|. .   .     . |||.
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTY

GYMAPEY---AVHRRLSPKADVFSFGV
 .||||    . . . | |.||.|.||
AWMAPEVIQQFRCEKYSEKCDVWSWGV

Kinase IRAK-Un_dn.AA Pkinase_Tyr 57-204 29 7.5e-35 118.65 Pfam 1-160 (270) Show / Hide
Range on Protein: 57-204
Range on HMM: 1-160/270
Sequence Identity: 29% (48 aa)

FSEENQLGQGGFGVVYKANLK-----DGTQVAVKKL--SLHSKQ-GKQEFVNELNIITGI-RHRNLAMLHGYCV-EANE--RLLVYEFLENGSLDSALFQ
 .   .||.| ||.|||. .|     ....||||.|  . ...|  ...| .|..| . . .| |.  |.| |. .      ..| |. ..|.|.. | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

S---SSALNWQSRFQITIGIARGLAYLHEESHFQIIHRDIKASNVLLDAKLQPKISDFGLSKL
      .|. .   |. . ||.|..||..     .||||. | |.|.. ... ||.||||...
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARD

Kinase IRAK-Un_dn.AA LRRK 57-244 23 1.1e-34 120.09 In-house 1-270 (351) Show / Hide
Range on Protein: 57-244
Range on HMM: 1-270/351
Sequence Identity: 23% (65 aa)

FSEENQLGQGGFG-VVYKANLKD---------------------------GTQVAVKKLSLH----------------------------------SKQG
. .|.|.|.|||| .||.|....                           .. ||.||. ..                                  .   
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

KQEFVNELNIITGIRHRNLAMLHGYCVEANERLLVYEFLENGSLDSALFQSS-SA-------LNWQSRFQITIGIARGLAYLHEESHFQ--IIHRDIKAS
 .|| .|. |. . .| |.  | |.|   . . .| |.. .|.|.. |. .. ..       ..|. . .| . ||.|..|||    .   ||||| |  
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS---HNPPIIHRDLKSP

NVLL---D---------AKLQPKISDFGLSKLFDLDGKHVVSKVAGTFGYMAPEYAVHR---RLSPKADVFSFGV
|.||   .         |    ||.|||.| .|  ... |.... |..|.||||          . |.|..|||.
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGM

Kinase IRAK-Un_dn.AA Dicty4 57-243 34 4.1e-34 111.28 In-house 1-204 (277) Show / Hide
Range on Protein: 57-243
Range on HMM: 1-204/277
Sequence Identity: 34% (72 aa)

FSEENQLGQGGFGVVYKANLKDGTQVAVKKLSLHSKQGK-----QEFVNELNIITGIRHRNLAMLHGYCV----EANERLLVYEFLENGSLDSALFQ---
   |. .|.|.|| |||.. . |..|||||| .| .|.      .|| .| .|   ||| |.  . |.|     .  . . | |..  |.| | |     
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNH-NQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---SSSALNWQSRFQ---ITIGIARGLAYLHEESHFQIIHRDIKASNVLLDAKLQPKISDFGLSKLF--DLDGKHVVSKVAGTFGYMAPEYAVHRRLSPK
   .|  | |  . .   . . .|||...||. .   |||||.|..| | |. .. |..|||||...  . | |   . ..|| ..||||  .|..   |
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEK

ADVFSFG
|||.|||
ADVYSFG

Kinase IRAK-Un_dn.AA STE 57-243 21 5e-34 117.58 In-house 1-255 (359) Show / Hide
Range on Protein: 57-243
Range on HMM: 1-255/359
Sequence Identity: 21% (56 aa)

FSEENQLGQGGFGVVYKANLKD----------------GTQVAVKKLSLHSKQG-----------------KQEFVNELNIITGIR--HRNLAMLHGYCV
.    ..|.|.||.||||  ..                |. .|.|...| ...                  .|.. .|..|    .  | |    .|...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EA-------NERLLVYEFLENGSLDSALFQSSSALN-------------WQSRFQITIGIARG-LAYLHEESHFQIIHRDIKASNVLLDAKLQPKISDFG
         .|  .. |....||||. . .  . ..              .    |.  | .| |.|||.     |||||||..|.||      |..|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LSKLFDLDGK------------HVVSK---VAGTFGYMAPEYAVHRR------LSPKADVFSFG
... .. ..               ..|   ..||  .||||    ..       . |.|. |.|
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLG

Kinase IRAK-Un_dn.AA Ciliate-E2 57-244 20 4.1e-31 104.03 In-house 1-284 (365) Show / Hide
Range on Protein: 57-244
Range on HMM: 1-284/365
Sequence Identity: 20% (61 aa)

FSEENQLGQGGFGVVYKANL-KDGTQVA--------------------VKKLSLHSKQGKQEFVNELNIITGIR----------------HRNLAMLHGY
.   ...|||.||.|||..  |.. |.|                     . .   .|...... .|..|.  |.                | |.  .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CV--EANERLLVYEFLENGSLDS-----ALFQ------SSSALNWQSRFQITIGIAR---------------GLAYLHEESHFQIIHRDIKASNVLLDAK
      |   || |... |.| .      ...          .... . .|.  |..               .| |||.. .  ||||||| .|.|.   
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF---

LQPKISDFGLSKLFDLDGK------------------------------HVVSKVAGTFGYMAPEYAV---------HRRLSPKADVFSFGV
  .||.|||||| .| | .                              ...  ..|| ||||||            . . . |.|..|.||
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

Kinase IRAK-Un_dn.AA TyrKc 57-325 25 4.9e-30 107.03 SMART 1-280 (280) Show / Hide
Range on Protein: 57-325
Range on HMM: 1-280/280
Sequence Identity: 25% (77 aa)

FSEENQLGQGGFGVVYKANLKDGTQVAVKKLSLHSKQGKQEFVNELNIITGI--RHRNLAMLHGYCVEA-------NERLLVYEFLENGSLDSALFQSSS
 . . .|| | ||.|||. .|  .|||||.|  ..   ...| .|..| . .  .| |.  |.|.|..           ..| |. ..|.|.. |  .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

ALNWQSRFQITIGIARGLAYLHEESHFQIIHRDIKASNVLLDAKLQPKISDFGLSKLFDLD------GKHVVSK---VA---GTFGYMAPEYAVHRRLSP
 |...   .. . ||.| .|||.    ..||||. | |.|...... ||||||||.  . |      ..  ..|    .        ||||   ... ..
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KADVFSFGVPVLV-ILSGRKCVDLARSSGQE-----HIVQMTWKLCEAGKLDECVDWKLGSDY----DPDEVYRMVHIALLCTQEREELRPVMSDVVTML
| ||.|||| ..  |..      .  .   .        |   .. ..|.  .. .  .         |||.|.   | . | .|  | || .|...  .
KSDVWSFGV-CMWEIFT------YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQ---IMKQCWHEDPEDRPTFSEIHECF





Kinase IRAK-Un_dn.AA S_TKc 57-325 22 9e-30 106.14 SMART 1-231 (231) Show / Hide
Range on Protein: 57-325
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

FSEENQLGQGGFGVVYKANLKD-GTQVAVKKLSLHSKQGKQEFVNELNIITGIRHRNLAMLHGYCVEANERLLVYEFLEN--GSLDSALFQSSS------
.   ...|.|.||.|||.  |. | .||.|...       . . .|..|    .| |.  |...... ..  .| |....  |.| . . .  .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

ALNWQSRFQITIGIARGLAYLHEESHFQIIHRDIKASNVLLDAKLQPKISDFGLSKLFDLDGKHVVSKVAGTFGYMAPEYAVHRRLSP-KADVFSFGVPV
    . || ..  |...|.|.|  || .|||||.| .|.|||   . ||.||||....        . . ||  |||||       .. |.|. |.|. .
FPE-HARF-YMYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LVILSGRKCVDLARSSGQEHIVQMTWKLCEAGKLDECVDWKLGSDYDPDEVYRMVHIALLCTQEREELRPVMSDVVT---------ML
   |.|.   .          .||..|..                        . ..   | |   | ||   .. .          .
YEMLCGYPPFP---------QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IRAK-Un_dn.AA Fer 57-203 32 1.3e-29 98.13 In-house 1-162 (283) Show / Hide
Range on Protein: 57-203
Range on HMM: 1-162/283
Sequence Identity: 32% (54 aa)

FSEENQLGQGGFGVVYKA--NLKDGT---------QVAVKKL--SLHSKQGKQEFVNELNIITG-IRHRNLAMLHGYCVEANERLLVYEFLENGSLDSAL
.  ...|| | || |||.   || .           |.|||.  .. .|  ..|| .| .|.     | |  ...|.||     ..| ||  .|||||.|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

FQSSS-ALNWQSRFQITIGIARGLAYLHEESHFQIIHRDIKASNVLLDA-KLQ--PKISDFGLSK
  ... ..    ........|.|..|||.     .||||| | |.|... |..  .||||||.|.
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKN---CIHRDIAARNCLYHKDKVKKKCKISDFGMSR

Kinase IRAK-Un_dn.AA Fer 222-244 52 0.001037 8.64 In-house 184-206 (283) Show / Hide
Range on Protein: 222-244
Range on HMM: 184-206/283
Sequence Identity: 52% (12 aa)

YMAPEYAVHRRLSPKADVFSFGV
..|||    .  ||| ||.||||
WLAPETWQTGIYSPKTDVWSFGV

Kinase IRAK-Un_dn.AA Pkinase_Tyr 223-244 50 0.009648 9.91 Pfam 181-202 (270) Show / Hide
Range on Protein: 223-244
Range on HMM: 181-202/270
Sequence Identity: 50% (11 aa)

MAPEYAVHRRLSPKADVFSFGV
||||   ... . | || ||||
MAPECINYGKFTTKSDVWSFGV

Kinase IRAK-Un_dn.AA IRAK 290-325 25 0.058279 2.94 In-house 282-317 (317) Show / Hide
Range on Protein: 290-325
Range on HMM: 282-317/317
Sequence Identity: 25% (9 aa)

SDYDPDEVYRMVHIALLCTQEREELRPVMSDVVTML
.. .|...  |   |. |. .|  .|. |  |.  |
PPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL

Kinase IRAK-Un_dn.AA TK 303-325 26 0.059342 1.47 In-house 464-486 (486) Show / Hide
Range on Protein: 303-325
Range on HMM: 464-486/486
Sequence Identity: 26% (6 aa)

IALLCTQEREELRPVMSDVVTML
. . | ..  | || .|... .|
LMQQCWHYDPEDRPTFSQLHEQL

Kinase IRAK-Un_dn.AA Fer 299-326 27 0.320656 0.04 In-house 255-283 (283) Show / Hide
Range on Protein: 299-326
Range on HMM: 255-283/283
Sequence Identity: 27% (8 aa)

RMVHIAL-LCTQEREELRPVMSDVVTMLL
... | .  | |.  | || |.... .| 
EIMQIMMKQCWQKDPEDRPTMKEICQKLK