IRAK-Un_am-1

Species: S.moellendorffii
Alias: IRAK-Un_am-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_am-1.AA Protein None 661 None Fasta, JSON
IRAK-Un_am-1.NA RNA None 1986 None Fasta, JSON
IRAK-Un_am-1.kin_dom Protein Kinase Domain None 195 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_am-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_am-1.AA TKL 375-563 26 1e-61 211.36 In-house 1-284 (364) Show / Hide
Range on Protein: 375-563
Range on HMM: 1-284/364
Sequence Identity: 26% (78 aa)

LGTGGFGEVYKGTLDD---------GVVVAIKLAKLGNIKGR---------------------------DQVINEVRVLSQVNHRNLVRIWGCCVDTGE-
.| |||||||||..           | .||.|  |  | . .                           .. ..|....|. .| |.|.. |.| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PLVVYEYIPNGTLYEWLHVGRGFLDWRSRLRIALQTAEGLAYLHSAAY-----PPIYHRDVKSSNILLDNSLV--------------A
            .  |.||.|.|.|.. ||       |  |.|.||..| |..||||        ||| ||| ||.|||.|. .               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

RVCDFGLSRLAEPDLSHVSTC------------------AQGTLGYLDPEYYR----------------KYQLTDKSDVYSFGVVLLELVT
 .|||||||  ... .   |                     ||.... ||  |                ... . |.||||||.|| |..|
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILT

Kinase IRAK-Un_am-1.AA IRAK 369-569 36 1.3e-54 187.74 In-house 1-225 (317) Show / Hide
Range on Protein: 369-569
Range on HMM: 1-225/317
Sequence Identity: 36% (82 aa)

FSKERLLGTGGFGEVYKGTLDDGV-VVAIK------LAKLGNIKGRDQV-INEVRVLSQVNHRNLVRIWGCCVDTGEPLVVYEYIPNGTLYEWLHVGRG-
|.|....| ||||.||.| ..    ..|.|        . . .. | |  .||..|..   | |.| . | | .....  ||.|.|||.|   |.   | 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-F---LDWRSRLRIALQTAEGLAYLHSAA-YPPIYHRDVKSSNILLDNSLVARVCDFGLSR---LAEPDLSHVSTCA-----QGTLGYLDPEYYR--KYQ
     | |  |. |.. || |. .||..    || |.|.||.|||||  ...  ||||| |    |.  .....||.     .||. |. ||. |  . |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTDKSDVYSFGVVLLELVTSQKAID
|| |.||||||.||||..| ..| .
LTKKTDVYSFGIVLLEVLTGCRAVY

Kinase IRAK-Un_am-1.AA Pkinase 369-563 28 1.2e-46 165.97 Pfam 1-207 (293) Show / Hide
Range on Protein: 369-563
Range on HMM: 1-207/293
Sequence Identity: 28% (60 aa)

FSKERLLGTGGFGEVYKGTLDDGVV-VAIKLAKLGNIKGRDQVIN----EVRVLSQVNHRNLVRIWGCCVDTGEPLVVYEYIPNG----TLYEWLH-VGR
. ..| .| |.||.|||..  .    ||.|  |. ..|   ....    |....  .|| | ||..... | ... .| || ..|     |.....   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GFL--DWRSRLRIALQTAEGLAYLHSAAYPPIYHRDVKSSNILLDNSLVA----RVCDFGLSRLAEPDLSHVSTCAQGTLGYLDPEYYR-KYQLTDKSDV
| .  ...   ....|...||.|.||     | |||.|..|||.||  .     ..|||||.....   ..  |   ||..|. ||  |     . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGVVLLELVT
.|.|..| |...
WSCGCILYEMLC

Kinase IRAK-Un_am-1.AA MLK 369-563 29 8.9e-44 149.75 In-house 1-231 (291) Show / Hide
Range on Protein: 369-563
Range on HMM: 1-231/291
Sequence Identity: 29% (70 aa)

FSKERLLGTGGFGEVYKGTLDDGV----VVAIKLAK---LGNIKG----RDQVINEVRVLSQVNHRN----LVRIWGCCVDTGE-PLVVYEYIPNGTLYE
.  .. .| |.||.|.||.         .||.| ..      .      ....  |.| |. ..|.|     ... |.| ...   ..| ||...| ||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLHVGRG-------------FLDWRSRLRIALQTAEGLAYLHSAAYPPIYHRDVKSSNILLDN------SLVARVCDFGLSRLAEPDLSHV---STCAQG
 || .|.               |  . ...||| |.|..|||| | .|| ||| ||.|||.|.       .....||||.||    |...     ....|
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR----DWHQMCTNMMSNAG

TLGYLDPEYY---RKYQLTDKSDVYSFGVVLLELVT
|. .  ||     |  . . |.||.|.|||| |..|
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT

Kinase IRAK-Un_am-1.AA Dicty4 369-563 35 2.3e-41 135.82 In-house 1-212 (277) Show / Hide
Range on Protein: 369-563
Range on HMM: 1-212/277
Sequence Identity: 35% (76 aa)

FSKERLLGTGGFGEVYKGTLDDGVVVAIKLAKLGNIKGRDQVIN----EVRVLSQVNHRNLVRIWGCCV----DTGEPLVVYEYIPNGTLYEWLHV----
  .| ..|.|.||||||||   |  ||.|.... |.. .   .|    ||  ...  | |..   | |       |... | || | |.||. ||     
INIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

--GRGFLDWRSRLR---IALQTAEGLAYLHSAAYPPIYHRDVKSSNILLDNSLVARVCDFGLSRLAEPDLSHVS--TCAQGTLGYLDPEYYRKYQLTDKS
   .  |||  ..|   .|. .| |...||.   | | ||| ||.|.| | .... |||||||..  .. .|    . | || ..  ||  ..   . |.
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCN-PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGVVLLELVT
|||||| || |..|
DVYSFGIVLWEILT

Kinase IRAK-Un_am-1.AA TK 369-563 16 1.8e-40 132.84 In-house 1-389 (486) Show / Hide
Range on Protein: 369-563
Range on HMM: 1-389/486
Sequence Identity: 16% (66 aa)

FSKERLLGTGGFG---EVYKGTLDDG--------------------------VVVAIKLAKLGNIKGRDQVIN--------------EVRVLSQVN----
   .. || | ||   |||||.. ..                          . ||.|  |.|.    .. .               |...... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLVRIWGCCVDT------------GEPLVVYEYIPNGT----LYEWLHVGRG---------------------------------------------
 | |.||. |.|..             . ...| || |.|     | ..|.  |.                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------FLDWRSRLRIALQTAEGLAYLHSAAY---PPIYHRDVKSSNILLDNSLV-----------ARVCDFG---
                              .|. . .| ...| |.|..||||  .   . . |||.   |.|.....|           ....|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRLAEPDLSHVSTCAQGTLG-------------------------YLDPEYYR---------KYQLTDKSDVYSFGVVLLELVT
     |.|  ..|   ...  .|| .                         .. ||  .         .   | ||||.||||.. |..|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT

Kinase IRAK-Un_am-1.AA TKL-Unique 373-565 30 6.7e-39 134.84 In-house 3-225 (290) Show / Hide
Range on Protein: 373-565
Range on HMM: 3-225/290
Sequence Identity: 30% (69 aa)

RLLGTGGFGEVYKGTL--DDGVVVAIK-LAKLGNIKGRDQVINEVRVLSQVN-HRNLVRIWGCCV----DTGEPLVVYEYIPNGTLYEWLH---------
 ..|.||.|.||||.   ..  .. .. .... |.. ..  .|||....  . | |.|.. | |.    . ..   | ||.| |.||. ||         
NKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEM-MQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

VGRGFLDWRSRLRIALQTAEGLAYLHSAAYPPIYHRDVKSSNILLDNS-----LVARVCDFGLSRLAEPDLSHVST--------CAQGTLGYLDPEYYRK
     |..  |...|.. | |. |||.   | |.||| ||||.|.||      . ...||||||...  ..   ..          .|.. .. ||  | 
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--YQLTDKSDVYSFGVVLLELVTSQ
  .| . ||||||||.|| |..|..
NFCQYSEKSDVYSFGIVLWEIATRK

Kinase IRAK-Un_am-1.AA S_TKc 369-649 22 2.2e-36 128.13 SMART 1-231 (231) Show / Hide
Range on Protein: 369-649
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

FSKERLLGTGGFGEVYKGTLDD-GVVVAIKLAKLGNIKGRDQVINEVRVLSQVNHRNLVRIWGCCVDTGEPLVVYEYIPN--GTLYEWLHVGRGF-----
. . |..| |.||.|||..  . | .||||  |       .....|...|.. .| |.|.. ....| ..  .| ||...  |.|.. ..  ..      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWRSRLRIALQTAEGLAYLHSAAYPPIYHRDVKSSNILLDNSLVARVCDFGLSRLAEPDLSHVSTCAQGTLGYLDPEYYRKYQLTD-KSDVYSFGVVLL
..     ... |....|.|.||     | |||.| .|||||.  .  .|||||.|.         |   ||. |. ||     . .  |.|..|.|..| 
FPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELVTSQKAIDFSRDQDDINLAMYVIARTERGDVMDVVDKRLLDFHNGDNAFEVVTRETIVGVVMLALNCLRESKDERPTMKEVSD-E-----LNYI
|... .   .      .... . .|                                    .  .  .||.   ..|||  |.   |       ..
EMLCGYPPFP------QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IRAK-Un_am-1.AA LRRK 369-563 28 4.1e-36 125.26 In-house 1-277 (351) Show / Hide
Range on Protein: 369-563
Range on HMM: 1-277/351
Sequence Identity: 28% (82 aa)

FSKERLLGTGGFG-EVYKGTLDD---------------------------GVVVAIKLAKLG------------------------------NIKGRDQV
. .|...| |||| .||.... .                           .  ||||  ...                              |. ..  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

INEVR----VLSQVNHRNLVRIWGCCVDTGEPLV-VYEYIPNGTLYEWLH--VGRGF------LDWRSRLRIALQTAEGLAYLHSAAYPPIYHRDVKSSN
 .| |    ..|  || |.| . | |    .||  | ||.|.|.||. ||     ||      ..|  .|.|||| |.|..||||.  ||| ||| || |
FREFRHEVWIMSHLNHPNIVSLKGFCI---HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHN-PPIIHRDLKSPN

ILL---D---------NSLVARVCDFGLSR-LAEPDLSH-VSTCAQGTLGYLDPEYYRKY---QLTDKSDVYSFGVVLLELVT
|||   .         .  .| ..|||.||    ....  ...|  |. |.. ||  |.    . |.|.|.||||..| ||.|
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCV-GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLT

Kinase IRAK-Un_am-1.AA Pkinase_Tyr 369-520 34 3.1e-34 116.57 Pfam 1-164 (270) Show / Hide
Range on Protein: 369-520
Range on HMM: 1-164/270
Sequence Identity: 34% (57 aa)

FSKERLLGTGGFGEVYKGTLD-----DGVVVAIKLAKLGNIKG---RDQVINEVRVLSQV-NHRNLVRIWGCCVDTGEP---LVVYEYIPNGTLYEWLHV
 .. . || | ||||||||..     ... ||.|  | |  .    |.  ..|.....|  .| |.||  |.|.| |||   ..| || |.| |.. |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

G---RGFLDWRSRLRIALQTAEGLAYLHSAAYPPIYHRDVKSSNILLDNSLVARVCDFGLSRLAEPD
    .. |.    | ...| |.|..||.|     . |||.   |.|.....|...|||||.|. ..|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYND

Kinase IRAK-Un_am-1.AA DRK 376-563 35 6.3e-34 112.32 In-house 8-197 (258) Show / Hide
Range on Protein: 376-563
Range on HMM: 8-197/258
Sequence Identity: 35% (68 aa)

GTGGFGEVYKGTLDDGVVVAIKLAKLGNIKGRD---QVINEVRVLSQVNHRNLVRIWGCCVDTGEPLVVYEYIPNGTLYEWLHVGRGFLDWRSRLRIALQ
| |..|||. ||   |  ||.| ... ||   .       |. ...|  | | .   | |    ..... ||.| | ||  ||     .||  ...... 
GRGNYGEVFRGTW-RGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFD

TAEGLAYLHSAAYPPIYHRDVKSSNILLDNSLVARVCDFGLSRLAEPDLSHVST-CAQGTLGYLDPEYYRKYQLTDKSDVYSFGVVLLELVT
 | |. |||.   | | ||| || | | | .    | |||||      ..|  .  . || .   ||  |    | | |||||..|| |.||
CAKGMIYLHCCN-PIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT

Kinase IRAK-Un_am-1.AA RIPK 375-567 30 2.5e-33 110.9 In-house 1-227 (290) Show / Hide
Range on Protein: 375-567
Range on HMM: 1-227/290
Sequence Identity: 30% (71 aa)

LGTGGFGEVYKGT-LDDGVVVAIKLAK-LGNIKG-----RDQVINEVRVLSQVNHRNLVRIWGCCVDT-----GE-PLVVYEYIPNGTLYEWLHVGRGF-
.| ||||||.| .  . |..||.| .. .  ..      | ... |.  . .  ... |.| | | .      .. .  | || .|| | . ||    . 
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

---LDWRSRLRIALQTAEGLAYLHSAAYPPIYHRDVKSSNILLDNSLVARVCDFGLSRLAEPDLSHVST--C----------AQ--GTLGYLDPEYYR--
   . |  | |.  ....|  ||||   ||| ||| | .|||.|| . . . ||||.   .   ||. .  |          ..  ||| |..|| .|  
HHPDPWPLRCRMIHEISCGMCYLHSMN-PPIIHRDLKPENILVDNNFHVKIADFGLATWMM--WSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTD

-KYQ---LTDKSDVYSFGVVLLELVTSQKA
 |      | |.|||||..|. |. |  ..
NKKPIKVVTPKYDVYSFAIVMWEVLTQKHP

Kinase IRAK-Un_am-1.AA TK-Unique 369-563 25 3.3e-32 108.4 In-house 1-234 (294) Show / Hide
Range on Protein: 369-563
Range on HMM: 1-234/294
Sequence Identity: 25% (60 aa)

FSKERLLGTGGFGEVYKGTLDD-------GVVVAIKLAKLGNIKG-RDQVINEVRVLSQVN-HRNLVRIWGCCVDTG-EPLVVYEYIPNGTLYEWLHVGR
.  ....|.| ||.|..|..          ..||.|. | .. .  ...  .| ......  | |.|.. |||....  .. ..||.|.|.|   |.  |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

G-------------------------FLDWRSRLRIALQTAEGLAYLHS--AAYPPIYHRDVKSSNILLDNSLVARVCDFGLSRLAEPDLSHVSTCAQGT
.                         ... .. ...| | | |..||.|       | |||. ..|.|| . .|. .||||..|  . .  ....| ||.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK---IVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR

LG--YLDPEYYR--KYQL-TDKSDVYSFGVVLLELVT
.   .. ||. .  . .  | ||||.||||.. |..|
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT

Kinase IRAK-Un_am-1.AA TyrKc 369-646 25 8.5e-32 112.88 SMART 1-280 (280) Show / Hide
Range on Protein: 369-646
Range on HMM: 1-280/280
Sequence Identity: 25% (77 aa)

FSKERLLGTGGFGEVYKGTLDDGVVVAIKLAKLGNIKGRDQVINEVRVLSQV--NHRNLVRIWGCCVDT-------GEPLVVYEYIPNGTLYEWLHVGRG
 .... || | ||||||||..  . ||.|  | .    |   ..| |.....  .| |.||. |.|..        . ...| || |.| | . |.  |.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

FLDWRSRLRIALQTAEGLAYLHSAAYPPIYHRDVKSSNILLDNSLVARVCDFGLSRLAEPD--------LSHVST--CAQ--GTLGYLDPEYYRKYQLTD
 | ..  | ...| |.| .||||    .. |||    |.|... ......||||||  . |          ....  ..     .  . ||  ...  | 
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDVYSFGVVLLELVTSQKAIDFSRDQDDI----NLAMYVIARTERGDVMDVVDK----RLLDFHNGDNAFEVVTRETIVGVVMLALNCLRESKDERPTM
||||.||||.. |. |     .      ..      .  ||.. ..|. |.  .                |     .    . .. . | .|  ..|||.
KSDVWSFGVCMWEIFT-----YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------F----VCCPDEMYQIMKQCWHEDPEDRPTF

KEVSDEL
.|. ...
SEIHECF

Kinase IRAK-Un_am-1.AA TK 624-646 26 0.001145 7.32 In-house 464-486 (486) Show / Hide
Range on Protein: 624-646
Range on HMM: 464-486/486
Sequence Identity: 26% (6 aa)

LALNCLRESKDERPTMKEVSDEL
| . | ..  ..|||.... ..|
LMQQCWHYDPEDRPTFSQLHEQL

Kinase IRAK-Un_am-1.AA IRAK 623-646 25 0.002646 7.76 In-house 294-317 (317) Show / Hide
Range on Protein: 623-646
Range on HMM: 294-317/317
Sequence Identity: 25% (6 aa)

MLALNCLRESKDERPTMKEVSDEL
..|. |. . . .|..|..|  .|
QCACCCGHHRANRRCDMAWVMQQL

Kinase IRAK-Un_am-1.AA TK-Unique 627-646 25 0.003205 7.1 In-house 275-294 (294) Show / Hide
Range on Protein: 627-646
Range on HMM: 275-294/294
Sequence Identity: 25% (5 aa)

NCLRESKDERPTMKEVSDEL
.|.... .|||.  .. ..|
SCWQWEPEERPSFRQIKHRL

Kinase IRAK-Un_am-1.AA TKL 624-646 26 0.003209 7.46 In-house 342-364 (364) Show / Hide
Range on Protein: 624-646
Range on HMM: 342-364/364
Sequence Identity: 26% (6 aa)

LALNCLRESKDERPTMKEVSDEL
|.  |  .  ..||...|. ..|
LMQDCWDHDPEKRPSFQEILKRL

Kinase IRAK-Un_am-1.AA Pkinase_Tyr 546-563 61 0.005716 10.68 Pfam 192-209 (270) Show / Hide
Range on Protein: 546-563
Range on HMM: 192-209/270
Sequence Identity: 61% (11 aa)

TDKSDVYSFGVVLLELVT
| ||||.||||.. |..|
TTKSDVWSFGVLMWEIFT

Kinase IRAK-Un_am-1.AA Dicty4 636-648 26 0.049733 2.76 In-house 263-277 (277) Show / Hide
Range on Protein: 636-648
Range on HMM: 263-277/277
Sequence Identity: 26% (4 aa)

RPTMKEVSDE--LNY
||...|.. .  |. 
RPSFEEIIQRRILEH

Kinase IRAK-Un_am-1.AA Pkinase_Tyr 626-646 28 0.247102 5.14 Pfam 250-270 (270) Show / Hide
Range on Protein: 626-646
Range on HMM: 250-270/270
Sequence Identity: 28% (6 aa)

LNCLRESKDERPTMKEVSDEL
. | ..  ..|||..|.  .|
KQCWHYDPEDRPTFSEIHEQL