Gene RKF3_a-2 (S.moellendorffii)

RKF3_a-2

Species: S.moellendorffii
Alias: RKF3_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
RKF3_a-2.AA Protein None 611 None Fasta, JSON
RKF3_a-2.NA RNA None 1836 None Fasta, JSON
RKF3_a-2.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of RKF3_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RKF3_a-2.AA TKL 301-495 25 2.4e-65 223.42 In-house 1-286 (364) Show / Hide 
Range on Protein: 301-495
Range on HMM: 1-286/364
Sequence Identity: 25% (73 aa)

IGEGGYGRVYRGVLAKRG-------NSEVAVKVMKA---------------------------SSKENNAEFLNEVEVINRVRHRNLLSVRGACVHAN--
||.||.| ||.|..   |       . .||||..|                             .. .. .. .|. ...| || |...  |.|   .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------GPDSQHILVYDYMPNGC-LKTYLSSGTLSWQQRRKIAIGIAVGINYLHNEV-----EPSIIHRDIKPSNILLDEDLN--------------AR
       ||..|. .|..|.|.|. | ...      |.|| ..|..|| |.||||..       | |||||.|..|||.||...              . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

VADFGLAKISPEGMS------------------HLTTRVAGTPIYMAVEYALYG----------------QCSDKVDVYSFGVLLLELMSGR
..||||..   . ..                    | .. ||| .|| |                     . | |.||||||..| |.....
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC
Kinase RKF3_a-2.AA IRAK 295-504 36 1.3e-58 201.03 In-house 1-231 (317) Show / Hide 
Range on Protein: 295-504
Range on HMM: 1-231/317
Sequence Identity: 36% (87 aa)

FSSKNFIGEGGYGRVYRGVLAKRGNS-EVAVK----VMKASSKENNAEFLN---EVEVINRVRHRNLLSVRGACVHANGPDSQHILVYDYMPNGCLKTYL
|.  | |||||.| ||||..  ...   .|||    . . | .|   .|.    |..| .| || |.... | |       ..| |||.||||| |   |
FHKDNRIGEGGFGCVYRGQW--KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTER----QCHCLVYPYMPNGSLEDRL

S----SGT---LSWQQRRKIAIGIAVGINYLHNEV-EPSIIHRDIKPSNILLDEDLNARVADFGLAKIS---P--EGMSH---LTTRVAGTPIYMAVEYA
.    ...   |||.|| .|..|.| ||..||.     .|||.|||..|||||.....  .||||.  .   .  |  .     | .| || .||. |. 
WCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFI

L--YGQCSDKVDVYSFGVLLLELMSGR-SALDTSQEN
    || . |.||||||. |||. .|.  ..| . |.
RDPQGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEH
Kinase RKF3_a-2.AA Pkinase 295-495 28 2.4e-47 168.4 Pfam 1-209 (293) Show / Hide 
Range on Protein: 295-495
Range on HMM: 1-209/293
Sequence Identity: 28% (64 aa)

FSSKNFIGEGGYGRVYRGVLAKRGNSEVAVKVMKASSKENNAE--FLN--EVEVINRVRHRNLLSVRGACVHANGPDSQHIL-VYDYMPNG----CLKTY
.  .  ||.|..|.||...  . |  .||||..| .... . .   ..  |... .|..| | .  ....       ..||  | .|...|     |..|
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDY

LS---SGTL--SWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIKPSNILLDEDLNA----RVADFGLAK-ISPEGMSHLTTRVAGTPIYMAVEYAL-YGQ
.|   .|..  |... ....  |. |..|.|..   .|||||.||.|||.|.. .     ...|||||| .. .  .. .| ..||| ||| |  . .  
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQY

CSDKVDVYSFGVLLLELMSGR
 . |||..|.|..| |...||
YGPKVDMWSCGCILYEMLCGR
Kinase RKF3_a-2.AA TKL-Unique 299-494 33 1.5e-44 154.31 In-house 3-224 (290) Show / Hide 
Range on Protein: 299-494
Range on HMM: 3-224/290
Sequence Identity: 33% (76 aa)

NFIGEGGYGRVYRGVLAKRGNSEVAVKVMKA-SSKENN--AEFLNEVEVINRVR-HRNLLSVRGACVHANGPDSQHILVYDYMPNGCLKTYLS-------
| |||||||.||.|. ..   ..||.|. .  ....|    || ||| .... . | |..   |.|.    . .. ..| .|.| | |  .|.       
NKIGEGGYGQVYKGKWRG---YPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

----SGTLSWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIKPSNILLDED-----LNARVADFGLAKISPEGMSHLTTRV--------AGTPIYMAVEYA
    . .|..||| |.|| || | .|||..  | |||||.|.||.|.|..     .|....||||.|..   .   ...          |....||.|  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV-

LYG---QCSDKVDVYSFGVLLLELMSG
| .   | | |.||||||. | |. ..
LRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase RKF3_a-2.AA MLK 295-495 23 2.8e-40 137.45 In-house 1-233 (291) Show / Hide 
Range on Protein: 295-495
Range on HMM: 1-233/291
Sequence Identity: 23% (56 aa)

FSSKNFIGEGGYGRVYRGVLAKRG--NSEVAVKVMK------ASSKENNAEFLNEVEVINRVRHRN----LLSVRGACVHANGPDSQHILVYDYMPNGCL
.  . .||.|..| |..|.  ..     .||||  .      ... .   .|  |..  ....|.|       ..|.|   .   ..  .|  |...|.|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP---CHFCIVMEYCEGGSL

KTYLSSGT---------------LSWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIKPSNILLDE------DLNARVADFGLAKISPEGMSHL---TTRV
 ..| ...                . ..  ..|  .| |..|||..  . |||||.|..|||.||      .......|||...     ...     .  
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD----WHQMCTNMMSN

AGTPIYMAVEY---ALYGQCSDKVDVYSFGVLLLELMSGR
|||...|| |    .  ...| |.||.|.||.| |.....
AGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase RKF3_a-2.AA LISK 300-497 28 4e-40 127.94 In-house 1-238 (296) Show / Hide 
Range on Protein: 300-497
Range on HMM: 1-238/296
Sequence Identity: 28% (70 aa)

FIGEGGYGRVYRGVLAKRGNSEVAVKVMKA-----SSKENNAEFLNEVEVINRVRHRNLLSVRGACVHANGPDSQHILVYDYMPNGCLKTYLSSG-----
 ||.|..| ||.| .   |. ..|.|  .        .|.   .| ||..... ||.| .   |.|.|    |.|  .|  |.  |.|. ||..      
EIGKGFFGKVYKGTHRQTGQ-VMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYH---NDGQLHIVTEYINGGDLHQYLKDMDKHKI

TLSWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIKPSNILLD----EDLNARVADFGLAKISPEGM----------------------------------
 |.|.|| ||| .|| |  |||   .  ||||| |  |.|..    .. ...|.|||.|..  .                                    
PLPWPQRVKIALDIACGMSYLH---SMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQR

-SHLTTRVAGTPIYMAVEYALYGQCSDKVDVYSFGVLLLELMSGRSA
 ...|  . |||. || |  |  . ....||.|||..|.|.  .. |
KRRMT--ICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA
Kinase RKF3_a-2.AA S_TKc 295-563 21 2.5e-38 134.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 295-563
Range on HMM: 1-231/231
Sequence Identity: 21% (63 aa)

FSSKNFIGEGGYGRVYRGVLAKRGNSEVAVKVMKASSKENNAEFLNEVEVINRVRHRNLLSVRGACVHANGPDSQHILVYDYMPN--GCLKTYLSSGT--
.   . ||.|..|.||...  |  . .||.|..|         ...|...  . .| |.    .....     .   .| .|...  | |..|. .    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LSWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIKPSNILLDEDLNARVADFGLAKISPEGMSHLTTRVAGTPIYMAVEYALYGQCSD-KVDVYSF
     ..  . |...  |. ...|.|.     |||||.||.||||||  .  ..|||||..         | . ||| ||| |     . .  |.|..|.
GLRFPFPE-HARFYMYQICCALEYCHSH---GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GVLLLELMSGRSALDTSQENPVHYHIVDWAWSLVKAGRLPEIIDEKIRDSDPAA--------IVLQQRFVLVGILCAHLLVAVRPPI
|..| |...|.   .  |.. .  .|.                      |..|            ..|     .| . ....  | .
GCILYEMLCGYPPFP--QMQMMFKKIG----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RKF3_a-2.AA LRRK 295-499 25 4.1e-38 132.41 In-house 1-284 (351) Show / Hide 
Range on Protein: 295-499
Range on HMM: 1-284/351
Sequence Identity: 25% (73 aa)

FSSKNFIGEGGYG-RVYRGVLAK-------------------------RGNSEVAVKVMKAS----------------------------------SKEN
. . . ||.||.| .|||. . .                         .  ..||.|...                                    . ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

NAEFLNEVEVINRVRHRNLLSVRGACVHANGPDSQHILVYDYMPNGCLKTYLS----SG------TLSWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIK
  || .|| .... .| |..|  | | |   |    ..| .|.|.| | ..|.    .|       .||. . |||. || |..|||.   |.||||| |
FREFRHEVWIMSHLNHPNIVSLKGFCIH---P---LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLK

PSNILL---D---------EDLNARVADFGLAKISPEGMSH-LTTRVAGTPIYMAVEYALYG---QCSDKVDVYSFGVLLLELMSGR-SALD
. ||||   .         .. .| .||||.  .      . .. .. |.|..|| |   |.   ....|||.||||..| ||....  . |
SPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase RKF3_a-2.AA STE 295-495 20 9.5e-37 127.31 In-house 1-265 (359) Show / Hide 
Range on Protein: 295-495
Range on HMM: 1-265/359
Sequence Identity: 20% (55 aa)

FSSKNFIGEGGYGRVYRGVLAK-----RGNSE---------VAVKVMKASSK-----------------ENNAEFLNEVEVINRVR--HRNLLSVRGACV
.    .||.|..| ||...  |     . . .         .|.|.|. ...                 |.  ..|.|... .. .  | |     |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HANGP---DSQHILVYDYMPNGCLKTYLSS---------------GTLSWQQRRKIAIGIAVG-INYLHNEVEPSIIHRDIKPSNILLDEDLNARVADFG
. . .   |..  ..  ||..|.|   . .               .... .| ..|.  |  |  .|||.     ||||||||.||||     .  .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LAK-ISPEGMSH--------------LTTRVAGTPIYMAVEYALY------GQCSDKVDVYSFGVLLLELMSGR
... ..... .                .. ..||| .|| |  .       .... |.|..|.| ...|.  |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase RKF3_a-2.AA TK 295-493 16 4.1e-36 118.01 In-house 1-389 (486) Show / Hide 
Range on Protein: 295-493
Range on HMM: 1-389/486
Sequence Identity: 16% (64 aa)

FSSKNFIGEGGYG---RVYRGVLAKRG------------------------NSEVAVKVMKASSKENNAE--------------FLNEVEVINRVR----
    . .||| .|   .||.| .  |.                        . .||||..|. . .. .|              ||.|.|..   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLLSVRGACVHANGP--------DSQHILVYDYMPNGC----LKTYLS--SGT--------------------------------------------
 | |...  |.|..  .         .   ..|  |||.|.    |..||   ...                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSWQQRRKIAIGIAVGINYLHNE----VEPSIIHRDIKPSNILLDEDLN-----------ARVADFGLA
                               |. .|.  ..  || |  |||      . . ..|||.   |.|..|...           ...|||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-----ISPEGMSHLTTRVAGTPI----------------------------YMAVEYAL---------YGQCSDKVDVYSFGVLLLELMS
.      . .  |.   ......                             .|| |  .         || .. | ||.|||||. |...
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase RKF3_a-2.AA Pkinase_Tyr 295-496 29 4.3e-36 122.86 Pfam 1-213 (270) Show / Hide 
Range on Protein: 295-496
Range on HMM: 1-213/270
Sequence Identity: 29% (65 aa)

FSSKNFIGEGGYGRVYRGVLA---KRGNSEVAVKVMKASSKENN---AEFLNEVEVINRV-RHRNLLSVRGACVHANGPDSQHILVYDYMPNGCLKTYLS
 .    .||| .|.||.|..    . .. .||||..| .. . .   ..|..|...     .| |...  |.|..  .|  |...|  |||.|.|..|| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLR

SG-----TLSWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIKPSNILLDEDLNARVADFGLAKISPEGMSHLTTRVAG---TPI-YMAVEYALYGQCSDK
.       |. ..  .... || | .||..     .||||.   |.|..|.. ....|||||.   .  .   .|..|    ||  || |   || .. |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTK

VDVYSFGVLLLELMS-GRS
 ||.|||||. |... |..
SDVWSFGVLMWEIFTYGEQ
Kinase RKF3_a-2.AA RIPK 301-495 26 2.3e-34 114.48 In-house 1-225 (290) Show / Hide 
Range on Protein: 301-495
Range on HMM: 1-225/290
Sequence Identity: 26% (61 aa)

IGEGGYGRVYRGVLAKRGNSEVAVKVMKASS------KENNAEFLNEVEVINRVRHRNLLSVRGACVHA-NGPDSQ-HILVYDYMPNGCLKTYLSSGT--
.| || | |.. . .. |  .||.|. .         .. . . . |..  .. |... ... | |       |..   .|  ||.|| |   |.. .  
VGGGGFGEVFKARHRHWGD-WVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPY

----LSWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIKPSNILLDEDLNARVADFGLAKISPEGMSHLTT-RV-------------AGTPIYMAVEYALY
    . |  |  .   |..| .|||.   | ||||| ||.|||.| .... .||||||.    ..||... |               || .||. |  . 
QHHPDPWPLRCRMIHEISCGMCYLHSM-NPPIIHRDLKPENILVDNNFHVKIADFGLATW--MMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRT

GQCSD------KVDVYSFGVLLLELMSGR
.. .       | |||||.... |.....
DNKKPIKVVTPKYDVYSFAIVMWEVLTQK
Kinase RKF3_a-2.AA Dicty4 295-491 33 1.3e-32 106.26 In-house 1-210 (277) Show / Hide 
Range on Protein: 295-491
Range on HMM: 1-210/277
Sequence Identity: 33% (72 aa)

FSSKNFIGEGGYGRVYRGVLAKRGNSEVAVKVM---KASSKENN-AEFLNEVEVINRVRHRNLLSVRGACVHANGPDSQHILVYDYMPNGCLKTYLSS--
    ..||.|..| ||.|    || .|||||..   .  . ||   ||..||.     || |..   |||       .    |  ||| | | . | .  
INIEQRIGKGSFGEVYKGTW--RG-KEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKP

------GTLSWQQRRK---IAIGIAVGINYLHNEVEPSIIHRDIKPSNILLDEDLNARVADFGLAKISPEGMSHLT--TRVAGTPIYMAVEYALYGQCSD
       .|.|  ...   .|. .| |.|.||.   | |||||.|..|.| |..... |.||||...  .. .| .  . ..||| .|| |         
SEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

KVDVYSFGVLLLEL
|.|||||| .| |.
KADVYSFGIVLWEI
Kinase RKF3_a-2.AA TyrKc 295-570 24 2.8e-26 94.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 295-570
Range on HMM: 1-280/280
Sequence Identity: 24% (74 aa)

FSSKNFIGEGGYGRVYRGVLAKRGNSEVAVKVMKASSKENNAEFLNEVEVINRV--RHRNLLSVRGACVHA--NGPD---SQHILVYDYMPNGCLKTYL-
 . .  .||| .|.||.|..      .||||..|...    ..|..| ..  ..  .| |..   |.|..   |       .. .|  |||.|.|| || 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLR

-SSGTLSWQQRRKIAIGIAVGINYLHNEVEPSIIHRDIKPSNILLDEDLNARVADFGLAKISPEG----MSHLTTRV----AGT---PI-YMAVEYALYG
 . ..|....  .... || | .|||      .||||.   |.|..|.. ....||||..   ..     |. . |.     |    ||  || |   ||
KHRPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

QCSDKVDVYSFGVLLLELMSGRSALDTSQENPVHYHIVDWAWSLVKAGRLPEIIDEKIRDSDP-----AAIVLQQRFVLVGILCAHLLVAVRPPISQALK
 .. | ||.||||.. |...        ..        . .  .||.|. ... ..      |     .   . |   .    | |   . ||  |.  .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDY----PMSFVCCPDEMYQ-IMK---QCWHEDPEDRPTFSEIHE

LL
..
CF
Kinase RKF3_a-2.AA IRAK 552-570 21 0.166872 1.3 In-house 299-317 (317) Show / Hide 
Range on Protein: 552-570
Range on HMM: 299-317/317
Sequence Identity: 21% (4 aa)

CAHLLVAVRPPISQALKLL
|.|  .. |... .....|
CGHHRANRRCDMAWVMQQL