Gene IRAK-Un_bo-1 (S.moellendorffii)

IRAK-Un_bo-1

Species: S.moellendorffii
Alias: IRAK-Un_bo-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_bo-1.AA Protein None 319 None Fasta, JSON
IRAK-Un_bo-1.NA RNA None 960 None Fasta, JSON
IRAK-Un_bo-1.kin_dom Protein Kinase Domain None 198 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_bo-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_bo-1.AA TKL 33-290 20 5.9e-52 178.93 In-house 1-364 (364) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-364/364
Sequence Identity: 20% (79 aa)

IGRGRFGLVYKGLLED---------GTIVAIKTRASAP------------------------------TQEFVTEVVNLSQLRHKNVVSLLGFCQEHDH-
||.|.|| |||| .           |. ||.|.  |                                 .... |.. .|.||| |.|...|.|.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------QMLVYDYLPNGSVSSHLCDPNGNPTGELDFKQRVAIALGAARGLEYLHSGN------PPRVHQDFKTSNVLLDENLV-----------
             ..|..| |.||  ..|            . ||. .||..|||..|||| |      || .| | |..|.|.|||.            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AKVTDVGLSKLLVTSHN-------------------AMPSANGSSSHFADPAAVYNTY--------------RVDPKSDVYSYGVFLLELISGRQAI
   .|..| |||. . .| |                   .  .  |.  . |  .   ...                ..|.||||.|. | |......  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

NRSRPAQPSPGIVEWESS------SSMEGMVDKSLVGTEE------------AGT---LLLLGLHCTAQSPEKRPTMSQVSQQV
       |  .. . .          ... .||.|  .                .   .  |  .| .. |||||..... .. 
-------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-Un_bo-1.AA IRAK 27-171 36 2.7e-38 133.35 In-house 1-159 (317) Show / Hide 
Range on Protein: 27-171
Range on HMM: 1-159/317
Sequence Identity: 36% (58 aa)

FNPSNLIGRGRFGLVYKGLLEDGT-IVAIK-------TRASAPTQEFVT---EVVNLSQLRHKNVVSLLGFCQEHDHQMLVYDYLPNGSVSSHL-CDPNG
|...|.|| | || ||.| .   | |.|.|       .      |.| .   |.  .. .||.|.|.|.|.| | .   |||.|.||||    | |  . 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

NPTGELDFKQRVAIALGAARGLEYLHSGNP--PRVHQDFKTSNVLLDENLVAKVTDVGL
.|   |   ||. |..|.|.|...||.  |  |  |.| |..|.|||.....| .| ||
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGL
Kinase IRAK-Un_bo-1.AA TKL-Unique 29-175 35 2.9e-30 103.99 In-house 1-167 (290) Show / Hide 
Range on Protein: 29-175
Range on HMM: 1-167/290
Sequence Identity: 35% (60 aa)

PSNLIGRGRFGLVYKGLLEDGTIVAIKTRA----SAPT--QEFVTEVVNLSQLR-HKNVVSLLGFCQ----EHDHQMLVYDYLPNGSVSSHLCD--PNG-
..|.||.| .| ||||    |..||||. .    | ..  |||  ||  .. |. |.|.| . |.|        .  .| .|.| ||  ..| .  .|  
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--NPTGELDFKQRVAIALGAARGLEYLHSGNPPRVHQDFKTSNVLLDEN-----LVAKVTDVGLSKLL
  |.  .|...||| .|. .|.|..|||. .||  | | |.||.|.|.|     . .|. |.||||..
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFN
Kinase IRAK-Un_bo-1.AA TK 27-222 16 1e-29 96.16 In-house 1-389 (486) Show / Hide 
Range on Protein: 27-222
Range on HMM: 1-389/486
Sequence Identity: 16% (65 aa)

FNPSNLIGRGRFG---LVYKGLLEDG--------------------------TIVAIKTRA--SAPTQE------------------FVTEVVNLSQ--L
    . .|.| ||    ||||.....                          | ||.|.    .| .||                  .. |   ...  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHKNVVSLLGFCQEH------------DHQMLVYDYLPNGS----VSSHLCDPNGNPTGE----------------------------------------
.|.|.|.|.| | ..             . |.|  | |.|.      ..| .  .. . |                                        
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDFKQRVAIALGAARGLEYLHSGNP----PRVHQDFKTSNVLLDENLV-----------AKVTDVGLSK
                               |. .|.. ... .|.|.||||| |       || |  . |.|..||.|           .|..| |||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LLVTSHN------------AMPSANGSSSHFADPAA---------------------VYN---------TYRVDPKSDVYSYGVFLLELIS
     |    ..            ..|      . |.| ..                     . |         . .  .||||.|.||.. |. .
QGSGVLARDIYSDDDYYRKSSYGTGRPM-W---P-FED-DPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_bo-1.AA MLK 27-188 25 3.3e-28 95.02 In-house 1-196 (291) Show / Hide 
Range on Protein: 27-188
Range on HMM: 1-196/291
Sequence Identity: 25% (51 aa)

FNPSNLIGRGRFGLVYKGLLEDGT----IVAIKTRASAP---------TQEFVTEVVNLSQLRHKN----VVSLLGFCQEHDHQ-MLVYDYLPNGSVSSH
.. .  || | || |.||     .    |||.|  .. .          ..| .|.  |. |.|.|    .. ..| |... ..  .|  |...|| .. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LCDPNGNPT---------GELDFKQRVAIALGAARGLEYLHSGNP-PRVHQDFKTSNVLLDE------NLVAKVTDVGLSKLLVTSHNA-MPSANGS
| . ....          .  |. . . .||  |||..||||  | | .| | | .|.|.||      ....|..| |.|. . ... . |.|. |.
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGT
Kinase IRAK-Un_bo-1.AA Pkinase_Tyr 27-182 26 6.8e-27 91.7 Pfam 1-175 (270) Show / Hide 
Range on Protein: 27-182
Range on HMM: 1-175/270
Sequence Identity: 26% (47 aa)

FNPSNLIGRGRFGLVYKGLLE-----DGTIVAIKTR---ASAP---TQEFVTEVVNLSQL-RHKNVVSLLGFCQ-EHDH--QMLVYDYLPNGSVSSHLCD
      .|.| || |||| .      ... ||.|.    |. .    ..|  |.  ..|| .|.|.|.|.| |  . ..   ..|  | |.|.  ..| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

PNGNPTGELDFKQRVAIALGAARGLEYLHSGNPPRVHQDFKTSNVLLDENLVAKVTDVGLSKLL-------VTSHNAM
.  .. . |. |. . ...  |.|.|||.| |   .| |  . |.|..||.|.|..| ||....       .......
HR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK
Kinase IRAK-Un_bo-1.AA LRRK 27-172 24 2.2e-24 83.19 In-house 1-225 (351) Show / Hide 
Range on Protein: 27-172
Range on HMM: 1-225/351
Sequence Identity: 24% (57 aa)

FNPSNLIGRGRFG-LVYKGLLED---------------------------GTIVAIKT--R-----------------------------------ASAP
.   ..|||| || .||.. ...                           .. ||||.  |                                   ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

TQEFVTEVVNLSQLRHKNVVSLLGFCQEHDHQMLVYDYLPNGSVSSHLCDPNGNP------TGELDFKQRVAIALGAARGLEYLHSGNPPRVHQDFKTSN
 .||  ||. .| |.| |.|||.|||  ... ..| .|.|.|. ...| ..  ..           .|..  |||  |.|.||||| ||| .| | |. |
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLK--IALQIAKGMEYLHSHNPPIIHRDLKSPN

VLL---D---------ENLVAKVTDVGLS
.||   .         .. .||. | |.|
ILLWSSPQNHSPNYPNAHVCAKIADFGIS
Kinase IRAK-Un_bo-1.AA Dicty4 27-188 31 7.2e-24 76.64 In-house 1-180 (277) Show / Hide 
Range on Protein: 27-188
Range on HMM: 1-180/277
Sequence Identity: 31% (57 aa)

FNPSNLIGRGRFGLVYKGLLEDGTIVAIKTR------ASAPT-QEFVTEVVNLSQLRHKNVVSLLGFCQ----EHDHQMLVYDYLPNGSVSSHLCD--PN
 |  ..||.| || ||||    |..||.|        ... . .||  ||  ....|| |.. ..| |     .    . |  |.| |.. | | |    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

GNPTGELDFKQRVA---IALGAARGLEYLHSGNPPRVHQDFKTSNVLLDENLVAKVTDVGLSKLL--VTSHNA-MPSANGS
  .  .||.  . .   .|. ||||. .||. ||  .| | |..| | |.|...||.| |||..   ...|.. . .| |.
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGT
Kinase IRAK-Un_bo-1.AA TK-Unique 27-173 26 1.6e-23 78.08 In-house 1-181 (294) Show / Hide 
Range on Protein: 27-173
Range on HMM: 1-181/294
Sequence Identity: 26% (48 aa)

FNPSNLIGRGRFGLVYKGLLEDGT-------IVAIKTRASAPTQE----FVTEVVNLSQLR-HKNVVSLLGFCQEHD-HQMLVYDYLPNGSVSSHLC---
..  ..||.|.|| |..| .. ..       .||.|..    |..    |  |   ...|  |.|.|..|| |.. |  .|... |.|.|.  ..|    
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

------------------DPNGNPTGELDFKQRVAIALGAARGLEYLHS--GNPPRVHQDFKTSNVLLDENLVAKVTDVGLSK
                  .| ...| ... |. . .| . |.|.|||.|   .   || |  ..|||| |..|.|..| |...
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI--VHRDLCARNVLLTEDKVCKICDFGMAR
Kinase IRAK-Un_bo-1.AA TyrKc 27-290 23 5.2e-21 77.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 27-290
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FNPSNLIGRGRFGLVYKGLLEDGTIVAIKT-RASAPTQEFVTEVVNLSQL--RHKNVVSLLGFCQEH-------DHQMLVYDYLPNGSVSSHLCDPNGNP
      .|.| || |||| .   . ||.|. ...|  ..|  |   ...|  .|.|.| |.| | ..       .  |.|  | |.|.  ..| .. .. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

TGELDFKQRVAIALGAARGLEYLHSGNPPRVHQDFKTSNVLLDENLVAKVTDVGLSKLLVTS------HNAMPSANGSSSHFADPAA-----VYNTYRVD
   |  |. . ... .|.| |||||   . .| |  . |.|..||...|..| |||. .         .    .. ......  |       . |...  
---LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKSDVYSYGVFLLELISGRQAINRSRPAQPSPGIVEWESSSSMEGMVDKSLVGTEEAGTLLLLGLH--------CT-----------AQSPEKRPTMSQV
.||||.|.|| . |.         .. .|| ||...         | .. ..   ..|  .    .        |.           .  ||.|||.|..
TKSDVWSFGVCMWEIF--------TYGQQPYPGMIQQ-------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

SQQV
 .. 
HECF
Kinase IRAK-Un_bo-1.AA Pkinase 27-224 24 1.3e-20 73.98 Pfam 1-209 (293) Show / Hide 
Range on Protein: 27-224
Range on HMM: 1-209/293
Sequence Identity: 24% (54 aa)

FNPSNLIGRGRFGLVYKGLLEDGTI-VAIKTRASAPTQEFVT-------EVVNLSQLRHKNVVSLLGFCQEHDHQMLVYDYLPNG----SVSSHLCDPNG
.     ||.| || |||.   .  . ||.|.     . . .        |.  .  |.|.|.| |.......||  .| .|...|    . ....     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

NPTGEL--DFKQRVAIALGAARGLEYLHSGNPPRVHQDFKTSNVLLDENLVA----KVTDVGLSKLLVTSHNAMPSANGSSSHFADPAAVYN-TYRVDPK
   | .  . ..   ...  .|||||.|| .   .| | | .|.|.|.| .     |..| ||.|.. . .|  ..    ..... |  | .     .||
WRHGCFYFSEWECKFYMYQILRGLEYCHS-M-GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAP-EVIRGGQYYGPK

SDVYSYGVFLLELISGR
.|..|.|. | |...||
VDMWSCGCILYEMLCGR
Kinase IRAK-Un_bo-1.AA RIPK 133-226 32 1.5e-20 66.68 In-house 117-227 (290) Show / Hide 
Range on Protein: 133-226
Range on HMM: 117-227/290
Sequence Identity: 32% (36 aa)

ARGLEYLHSGNPPRVHQDFKTSNVLLDENLVAKVTDVGLSKLLVTS--HN---------AMPSAN--GSSSHFADPAAVY--NTYR---VDPKSDVYSYG
..|  |||| |||  | | |..|.|.| |. .|. | ||.. . .|  |.          | |.|  |  |. . | .    |  .   |.||.||||..
SCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMP-PEHFRTDNKKPIKVVTPKYDVYSFA

VFLLELISGRQA
. . |. .....
IVMWEVLTQKHP
Kinase IRAK-Un_bo-1.AA UTK 27-175 26 3e-20 65.96 In-house 1-178 (296) Show / Hide 
Range on Protein: 27-175
Range on HMM: 1-178/296
Sequence Identity: 26% (47 aa)

FNPSNLIGRGRFGLVYKGLLEDGT------IVAIKTRA---SAPTQ-----EFVTEVV---NLSQLR-HKNVVSLLGFCQEHDHQMLVYDYLPNGSVSSH
  .....|.|.|| |.|. ... .      .||.|..    .|...     .|  |      ..|.. | ||. |.| |      |.|. | .||. .| 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LCDPNGNPT-GELDFK--QRVAIALGAARGLEYLHSGNPPRVHQDFKTSNVLLDEN-------LVAKVTDVG---LSKLL
|..   .|   .. ..  ||.  |.  |||..|||| .   || |    |.|....       .|.|. |.|   .|...
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG--FVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRV
Kinase IRAK-Un_bo-1.AA S_TKc 27-294 22 4.1e-16 59.42 SMART 1-231 (231) Show / Hide 
Range on Protein: 27-294
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

FNPSNLIGRGRFGLVYKGLLED-GTIVAIKTRASAPTQEFVTEVVNLSQLRHKNVVSLLGFCQEHDHQMLVYDYLPN--GSVSSHLCDPNGNPTGE-LDF
.   ..||.| || |||.   . | |||||       . .  |.  |.. .|.|.| |....|. ||  .| .|...  |.. ..... ......  .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

KQRVAIALGAARGLEYLHSGNPPRVHQDFKTSNVLLDENLVAKVTDVGLSKLLVTSHNAMPSANGSSSHFADPAAVYNTYRVDP-KSDVYSYGVFLLELI
 .   ..   ...|||.|| .   .| | | .|.||||  . |..| ||...|        .    . ..  |  .      .. |.|..| |. | |..
-HARFYMYQICCALEYCHSHG--IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

SGRQAINRSRPAQPSPGIVEWESSSSMEGMVDKSLVGTEEAGTLLLLGLHCTAQSPEKRPTMSQVSQ-----QVERIL
.|.                       |. | .| .        .. .  .|    ||||||  .. |          .
CGYPPFP------------------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-Un_bo-1.AA RIPK 33-104 26 3e-06 17.35 In-house 1-88 (290) Show / Hide 
Range on Protein: 33-104
Range on HMM: 1-88/290
Sequence Identity: 26% (23 aa)

IGRGRFGLVYKGLLED-GTIVAIKTRASAP---------TQEFVTEVVNLSQLRHKNVVSLLGFCQEHDH------QMLVYDYLPNGS
.|.| || |.|    . |. ||.|   . .          ..   |.  . .||....|...||||. .       . .|  | .|||
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGS
Kinase IRAK-Un_bo-1.AA IRAK 206-234 33 1.2e-05 16.19 In-house 203-232 (317) Show / Hide 
Range on Protein: 206-234
Range on HMM: 203-232/317
Sequence Identity: 33% (10 aa)

PKSDVYSYGVFLLELISGR-QAINRSRPAQ
.|.|||| |. |||...|. .. ..... .
KKTDVYSFGIVLLEVLTGCRAVYDDRPEHY
Kinase IRAK-Un_bo-1.AA LRRK 207-226 38 0.000105 12.56 In-house 262-282 (351) Show / Hide 
Range on Protein: 207-226
Range on HMM: 262-282/351
Sequence Identity: 38% (8 aa)

KSDVYSYGVFLLELISGR-QA
|.|.||.|..| ||.... ..
KVDCYSFGMILWELLTRQHHP
Kinase IRAK-Un_bo-1.AA LRRK 271-292 36 0.000322 10.81 In-house 330-351 (351) Show / Hide 
Range on Protein: 271-292
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

HCTAQSPEKRPTMSQVSQQVER
|| .. |.|||..||. .. . 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAK-Un_bo-1.AA TK 270-290 42 0.000331 9.16 In-house 466-486 (486) Show / Hide 
Range on Protein: 270-290
Range on HMM: 466-486/486
Sequence Identity: 42% (9 aa)

LHCTAQSPEKRPTMSQVSQQV
. | .  ||.|||.||. .| 
QQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-Un_bo-1.AA Dicty4 276-292 26 0.000542 9.4 In-house 259-277 (277) Show / Hide 
Range on Protein: 276-292
Range on HMM: 259-277/277
Sequence Identity: 26% (5 aa)

SPEKRPTMSQVSQQ--VER
.|..||......|.   | 
DPQHRPSFEEIIQRRILEH
Kinase IRAK-Un_bo-1.AA MLK 207-224 44 0.002146 7.79 In-house 216-233 (291) Show / Hide 
Range on Protein: 207-224
Range on HMM: 216-233/291
Sequence Identity: 44% (8 aa)

KSDVYSYGVFLLELISGR
|.||.|.|| | |.....
KCDVWSWGVVLWEMLTRE
Kinase IRAK-Un_bo-1.AA UTK 272-290 31 0.002158 7.47 In-house 278-296 (296) Show / Hide 
Range on Protein: 272-290
Range on HMM: 278-296/296
Sequence Identity: 31% (6 aa)

CTAQSPEKRPTMSQVSQQV
| ...|..||.. .. ||.
CWHYDPQERPDFEDLVQQM
Kinase IRAK-Un_bo-1.AA TK-Unique 206-222 47 0.004545 6.57 In-house 218-234 (294) Show / Hide 
Range on Protein: 206-222
Range on HMM: 218-234/294
Sequence Identity: 47% (8 aa)

PKSDVYSYGVFLLELIS
.||||.|.||.. |. .
TKSDVWSFGVLMWEIFT
Kinase IRAK-Un_bo-1.AA UTK 207-223 47 0.005499 6.06 In-house 220-236 (296) Show / Hide 
Range on Protein: 207-223
Range on HMM: 220-236/296
Sequence Identity: 47% (8 aa)

KSDVYSYGVFLLELISG
||||.|.||.. |. ..
KSDVWSFGVVCWEIWTW
Kinase IRAK-Un_bo-1.AA TK-Unique 272-290 31 0.01229 5.06 In-house 276-294 (294) Show / Hide 
Range on Protein: 272-290
Range on HMM: 276-294/294
Sequence Identity: 31% (6 aa)

CTAQSPEKRPTMSQVSQQV
|.  .||.||. .|. .. 
CWQWEPEERPSFRQIKHRL
Kinase IRAK-Un_bo-1.AA MLK 275-290 43 0.025859 3.99 In-house 276-291 (291) Show / Hide 
Range on Protein: 275-290
Range on HMM: 276-291/291
Sequence Identity: 43% (7 aa)

QSPEKRPTMSQVSQQV
| |.|||...|. |. 
QDPHKRPSFRQIVQHL
Kinase IRAK-Un_bo-1.AA TKL-Unique 207-225 47 0.032289 3.84 In-house 208-226 (290) Show / Hide 
Range on Protein: 207-225
Range on HMM: 208-226/290
Sequence Identity: 47% (9 aa)

KSDVYSYGVFLLELISGRQ
||||||.|. | |.... .
KSDVYSFGIVLWEIATRKI
Kinase IRAK-Un_bo-1.AA Pkinase_Tyr 207-225 50 0.041056 7.78 Pfam 194-213 (270) Show / Hide 
Range on Protein: 207-225
Range on HMM: 194-213/270
Sequence Identity: 50% (10 aa)

KSDVYSYGVFLLELIS-GRQ
||||.|.|| . |... |.|
KSDVWSFGVLMWEIFTYGEQ
Kinase IRAK-Un_bo-1.AA Dicty4 207-220 57 0.108789 1.61 In-house 197-210 (277) Show / Hide 
Range on Protein: 207-220
Range on HMM: 197-210/277
Sequence Identity: 57% (8 aa)

KSDVYSYGVFLLEL
|.||||.|  | |.
KADVYSFGIVLWEI
Kinase IRAK-Un_bo-1.AA IRAK 272-290 31 0.186097 1.13 In-house 299-317 (317) Show / Hide 
Range on Protein: 272-290
Range on HMM: 299-317/317
Sequence Identity: 31% (6 aa)

CTAQSPEKRPTMSQVSQQV
|...   .|..| .| || 
CGHHRANRRCDMAWVMQQL
Kinase IRAK-Un_bo-1.AA Pkinase_Tyr 270-290 38 0.220131 5.31 Pfam 250-270 (270) Show / Hide 
Range on Protein: 270-290
Range on HMM: 250-270/270
Sequence Identity: 38% (8 aa)

LHCTAQSPEKRPTMSQVSQQV
..| .. ||.|||.|.. .| 
KQCWHYDPEDRPTFSEIHEQL