Gene IRAK-Un_bf (S.moellendorffii)

IRAK-Un_bf

Species: S.moellendorffii
Alias: IRAK-Un_bf
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_bf.AA Protein None 314 None Fasta, JSON
IRAK-Un_bf.NA RNA None 945 None Fasta, JSON
IRAK-Un_bf.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_bf.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_bf.AA TKL 19-285 20 2.7e-60 206.62 In-house 1-364 (364) Show / Hide 
Range on Protein: 19-285
Range on HMM: 1-364/364
Sequence Identity: 20% (77 aa)

LGEGGSAVVYKGIIQTIG---------PVAIKFLQIKA--------------------------HSISNEEFINEVSTISYLQHKNLIRLVGFCCEGEH-
.|.||...||||. . .|         .||.| . ..                            |  ......|.  .| |.| |.....|.||.... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEFLENNS-LALAILSGPNKLYIPWAKRYEICLGVARGIAYLHEESR-----TRIVHRDIKASNILLDKEFN------------
              .|.|. .. | | . .          | .|  ..|..|||..||| .         |.|||.| .|||.|. ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--ARVSDFGLARLL----KDGDTH--------------LSTRVAGTFGYLAPEYAL----------------RGKLTEKADVYSFGILLLEILSGRSSID
  . ..||||.| .    .. ||                . .. ||....|||                    .. .||.|||||||.| |||...    
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

FELPPE--KSFLLEWAWELYEEGQWLDLVDEKLPPET----------CPKEELQRVMTVSLICTQGAPSARPAMSRVVAML
   | .  ...  ...   .|| .... .. . ||            ...  ....      | .  |..|| .....  |
---PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-Un_bf.AA IRAK 13-212 35 1.9e-53 183.88 In-house 1-221 (317) Show / Hide 
Range on Protein: 13-212
Range on HMM: 1-221/317
Sequence Identity: 35% (78 aa)

FHAANKLGEGGSAVVYKGIIQTIG-PVAIK-FLQIKAHSI--SNEEFIN---EVSTISYLQHKNLIRLVGFCCEGEHRLLVYEFLENNSLA--LAILSGP
||..|..|||| ..||.| .. .. ..|.| . . .  |.  . ..|     |. . . ..|.|.  | |.| |..   |||... | ||   |. . | 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

NKL-YIPWAKRYEICLGVARGIAYLHEES-RTRIVHRDIKASNILLDKEFNARVSDFGLARLL--KDGDTHLST------RVAGTFGYLAPEYAL--RGK
. .   .| .| .||.| |.|| .||. .  | | |.||| .|||||. |..  .||||.|    . .  . .       .| ||  |..||.     |.
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTEKADVYSFGILLLEILSGR
|| | ||||||| |||.|.|.
LTKKTDVYSFGIVLLEVLTGC
Kinase IRAK-Un_bf.AA TKL-Unique 15-211 30 3.9e-47 162.9 In-house 1-224 (290) Show / Hide 
Range on Protein: 15-211
Range on HMM: 1-224/290
Sequence Identity: 30% (69 aa)

AANKLGEGGSAVVYKGIIQTIGPVAIKFLQI--KAHSISNEEFINEVSTISYLQ-HKNLIRLVGFCC----EGEHRLLVYEFLENNSLALAIL-------
  ||.||||...||||.  .. ||||| . .  . .... .||.|||.... |. |.|. ...|.|        .. .| |... .||   .        
FWNKIGEGGYGQVYKGKWRGY-PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

SGPNKLYIPWAKRYEICLGVARGIAYLHEESRTRIVHRDIKASNILLDKE-----FNARVSDFGLARLLKDGDTHLSTRV--------AGTFGYLAPEYA
  .|.. .....|. . . .|.|  ||| .. . | |||.| ||.|.| .     .|....||||.....  ..  ...          |.| ..|||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV-

LRG---KLTEKADVYSFGILLLEILSG
||.   . .||.||||||| | ||...
LRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAK-Un_bf.AA Pkinase 13-212 26 2.6e-41 147.14 Pfam 1-209 (293) Show / Hide 
Range on Protein: 13-212
Range on HMM: 1-209/293
Sequence Identity: 26% (57 aa)

FHAANKLGEGGSAVVYKGIIQTIG-PVAIKFLQIKAHSISNEEFIN-----EVSTISYLQHKNLIRLVGFCCEGEHRLLVYEFLENN----SLALAILSG
.|   |.|.|....|||.. .  |  ||.| .  .  ... .. ..     |..    |.|.| .|| ... .. |  .| |..|.     .|. ...|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-DYIST

PNKLYI--PWAKRYEICLGVARGIAYLHEESRTRIVHRDIKASNILLDKEFNA----RVSDFGLARLLKDGDTHLSTRVAGTFGYLAPEYAL-RGKLTEK
 ..  .  ..     ... ..||..|.|..   .|.|||.| .|||.|.. .     ...|||||....    .  | ..|| .|.|||  . . . . |
WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

ADVYSFGILLLEILSGR
.|..|.|..| | |.||
VDMWSCGCILYEMLCGR
Kinase IRAK-Un_bf.AA TK 13-210 16 7.9e-38 123.87 In-house 1-389 (486) Show / Hide 
Range on Protein: 13-210
Range on HMM: 1-389/486
Sequence Identity: 16% (65 aa)

FHAANKLGEGGSA---VVYKGIIQTIG--------------------------PVAIKFLQIKAHSISNEEFI-------------NEVSTISYLQ----
 .  .|||||      .||||. ....                          |||.| |  .... ..|.|              .|.. .. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNLIRLVGFCCEG------------EHRLLVYEFLENNS----LALAILS-GPNKLY-----------------------------------------
 |.|..||.| |..|            |. ..| |. .. .    |     .  |..                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------IPWAKRYEICLGVARGIAYLHEE--SRT--RIVHRDIKASNILLDKEFN-----------ARVSDFGLA
                               .. . .  .|. .|.| .|||.   .    ..||||. | |.|.... .           ....||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

R-----LLKDGDTHLSTRVAGTFG----------------------------YLAPEYAL---------RGKLTEKADVYSFGILLLEILS
|     | .| . .   ..... |                            ..|||  .          || |.| ||.|||.|. ||..
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_bf.AA Dicty4 13-209 28 2.7e-35 115.26 In-house 1-211 (277) Show / Hide 
Range on Protein: 13-209
Range on HMM: 1-211/277
Sequence Identity: 28% (62 aa)

FHAANKLGEGGSAVVYKGIIQTIGPVAIKFL---QIKAHSISNEEFINEVSTISYLQHKNLIRLVGFCC----EGEHRLLVYEFLENNSLALAILS----
    ...|.|. . ||||.   .  ||.| |   .... .   .|| .||.  . ..| |.. . | |     . .  . | |..   .|.  ...    
INIEQRIGKGSFGEVYKGTWRGKE-VAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

GPNKLYIPWAKRYE---ICLGVARGIAYLHEESRTRIVHRDIKASNILLDKEFNARVSDFGLARLLKDGDTHLS--TRVAGTFGYLAPEYALRGKL-TEK
   .  ..|  .     ... .|||...||. . ..|.|||.|..|.| || ... |.||||... | . .|    . ..|| .. |||  ....  .||
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPE-VMMHQPYNEK

ADVYSFGILLLEIL
||||||||.| |||
ADVYSFGIVLWEIL
Kinase IRAK-Un_bf.AA Pkinase_Tyr 13-213 30 2.9e-35 120.06 Pfam 1-213 (270) Show / Hide 
Range on Protein: 13-213
Range on HMM: 1-213/270
Sequence Identity: 30% (66 aa)

FHAANKLGEGGSAVVYKGIIQ-----TIGPVAIKFLQIKAHSIS--NEEFINEVSTISYL-QHKNLIRLVGFCC-EGEH--RLLVYEFLENNSLALAILS
 .   |||||   .||||.       |  |||.| |  .|..     |.|..|... . | .|.|..||.| |  .||.   ..| |. .. .|     .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

G-PNKLYIPWAKRYEICLGVARGIAYLHEESRTRIVHRDIKASNILLDKEFNARVSDFGLARLL-KDGDT-HLST----RVAGTFGYLAPEYALRGKLTE
  ..|  ..     ..|. .|.| .||..     ..|||. | |.|..... ....||||||.. .|.   . ..     .  .    |||    || |.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFTT

KADVYSFGILLLEILS-GRS
| ||.|||.|. ||.. |..
KSDVWSFGVLMWEIFTYGEQ
Kinase IRAK-Un_bf.AA MLK 13-212 25 5e-35 118.99 In-house 1-233 (291) Show / Hide 
Range on Protein: 13-212
Range on HMM: 1-233/291
Sequence Identity: 25% (60 aa)

FHAANKLGEGGSAVVYKGIIQTIG----PVAIKFLQIKAHSISN-----EEFINEVSTISYLQHKN----LIRLVGFCCEGEH-RLLVYEFLENNSLALA
.    ..|.|.. .|.||  .        ||.|   . . ..|      ..|  |.   . |.|.|     |...| | . ..  ..| |..|. ||.  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

ILSGPNKLY-----------IPWAKRYEICLGVARGIAYLHEESRTRIVHRDIKASNILLD------KEFNARVSDFGLARLLKDG-DTHLSTRVAGTFG
. ....| .           .. .    ..| .|||..|||.. .  |.|||.| .|||.|      .. .....|||..| ...  ... |.  |||. 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSN--AGTYA

YLAPEY---ALRGKLTEKADVYSFGILLLEILSGR
. |||    .  .| .||.||.|.|..| |.|...
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase IRAK-Un_bf.AA LRRK 13-212 22 1.4e-33 116.15 In-house 1-279 (351) Show / Hide 
Range on Protein: 13-212
Range on HMM: 1-279/351
Sequence Identity: 22% (64 aa)

FHAANKLGEGGSA-VVYKGIIQT---------------------------IGPVAIKFLQIK-----------------------------------AHS
.   ...|.||.. .||... .                              .|||| . .                                    ...
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

ISNEEFINEVSTISYLQHKNLIRLVGFCCEGEHRLLVYEFLENNSLALAILSGP-NKL-----YIPWAKRYEICLGVARGIAYLHEESRT-RIVHRDIKA
 .  || .||. .| |.| |.. |.|||   ... .| |.. . .|   . .   ...      |.|  ...| | .|.|..|||  |..  |.||| | 
FR--EFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH--SHNPPIIHRDLKS

SNILL---D---------KEFNARVSDFGLARLLKDGDTH-LSTRVAGTFGYLAPEYALRG---KLTEKADVYSFGILLLEILSGR
 ||||   .          . .| ..|||. |.    ... .  .. |..|..|||    .     |||.|.||||..| |.|...
PNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase IRAK-Un_bf.AA Src 13-212 33 4.1e-31 102.9 In-house 1-198 (255) Show / Hide 
Range on Protein: 13-212
Range on HMM: 1-198/255
Sequence Identity: 33% (68 aa)

FHAANKLGEGGSAVVYKGIIQTIGPVAIKFLQIKAHSISNEEFINEVSTISYLQHKNLIRLVGFCCEGEHRLLVYEFLENNSLALAILS-GPNKLYIPWA
..   |||.|    |..|. .   .||.| |  .    |.| |  |  .   |.|..|..|   | ..|  . | |. ...|| |. |   .   ...  
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSL-LDYLKKDGEGRHLHLP

KRYEICLGVARGIAYLHEESRTRIVHRDIKASNILLDKEFNARVSDFGLARLLKDGDTHLSTRVAGTFGY--LAPEYALRGKLTEKADVYSFGILLLEIL
.  ..   ||.| |||   .. ...|||  | |.| ...  . | |||||||.|..|   . |    | .   ||| ...|. | |.|| |||||| || 
QLIDMAAQVAEGMAYL---ESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIV

S-GR
. ||
TYGR
Kinase IRAK-Un_bf.AA TyrKc 13-285 25 4.3e-31 110.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-285
Range on HMM: 1-280/280
Sequence Identity: 25% (77 aa)

FHAANKLGEGGSAVVYKGIIQTIGPVAIKFLQIKAHSISNEEFINEVSTISYL--QHKNLIRLVGFCCEG-------EHRLLVYEFLENNSLALAILSGP
 .   |||||   .||||.     .||.| |.  |     |.|..| .  . |  .|.|..||.| | ..       |  ..| |. .. .|   . .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

NKLYIPWAKRYEICLGVARGIAYLHEESRTRIVHRDIKASNILLDKEFNARVSDFGLARLLKDG-------DTHL-----STRVAGTFGYLAPEYALRGK
.|  .....  ..|. .|.| .|||.    ...|||. | |.|..... ...|||||.| ..|.       |.       ...       .|||    ||
PK--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LTEKADVYSFGILLLEILSGRSSIDFELPPEKS-----FLLEWAWELYEEGQWLDLVDEKLPPET----CPKEELQRVMTVSLICTQGAPSARPAMSRVV
 |.| ||.|||... ||..      .  .|           . . |. ..|  ..  .. . |      ||.|  | .|   . | .  |. || .| ..
FTTKSDVWSFGVCMWEIFT------YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQ-IM---KQCWHEDPEDRPTFSEIH

AML
  .
ECF
Kinase IRAK-Un_bf.AA STE 13-212 20 1.1e-30 105.68 In-house 1-265 (359) Show / Hide 
Range on Protein: 13-212
Range on HMM: 1-265/359
Sequence Identity: 20% (55 aa)

FHAANKLGEGGSAVVYKGIIQ----------------TIGPVAIKFLQIKAHSI----------------SNEEFINEVSTISYLQ--HKNLIRLVGFCC
.    |.|.|.. .|||..                  |   .||| . ..  .                   .....|... . ..  |.| ..  | . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------EHRLLVYEFLENNSLALAILS--GPNK---------LYIPWAKRYEICLGVARG-IAYLHEESRTRIVHRDIKASNILLDKEFNARVSDFG
 .       ..  .. |.... ||   | .  |..|          ..|      ||  . .|  .|||.     |.|||||..||||     .  .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LARLLKDG-------------DTHLSTR--VAGTFGYLAPEYALR------GKLTEKADVYSFGILLLEILSGR
..  | |              .|  . |  ..||  . |||  ..      .. ..|.|..|.|....| . |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase IRAK-Un_bf.AA Dicty4-Unclassified 13-211 29 3.8e-30 100.41 In-house 1-204 (263) Show / Hide 
Range on Protein: 13-211
Range on HMM: 1-204/263
Sequence Identity: 29% (62 aa)

FHAANKLGEGGSAVVYKGIIQTIGPVAIKFLQIKAHSIS---NEEFINEVSTISYLQHKNLIRLVGFCCEG-EHR---LLVYEFLENNSLALAILSGPNK
      .|.|  . |.||.      ||.| .     .      ..|  ||     .|| ||... | |     |.     | ||.    |   | | |  
IQIDQFIGKGHFSKVHKGNWKGKD-VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

LYIPWAKRY----EICLGVARGIAYLHEESRTRIVHRDIKASNILLDKEFNARVSDFGLARLLKDGDTHLSTRVAGTFGYLAPEYALRGKLTEKADVYSF
   |          . . .|.|...||  .|  ..|||||.||||.|| ||... |||..|      .   | .|||    .||       . |.||||.
QQQPIKLDDTLIIKYAFDIAQGMQHLH--TRN-FIHRDIKSSNILMDKHFNIKIADFGISRVID--FNFNMTTIAGTPKWESPECLMHESYNQKSDVYSY

GILLLEILSG
...| | . |
AMMLYELATG
Kinase IRAK-Un_bf.AA S_TKc 13-309 20 1.3e-28 102.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-309
Range on HMM: 1-231/231
Sequence Identity: 20% (63 aa)

FHAANKLGEGGSAVVYKGI-IQTIGPVAIKFLQIKAHSISNEEFINEVSTISYLQHKNLIRLVGFCCEGEHRLLVYEFLEN--NSLALAILSGPNK----
..  .|.|.|. ..|||.. . |   |||| .         | ...|..  .  .|.|...| ... . .|  .| |....   .|   | . . .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LYIPWAKRYEICLGVARGIAYLHEESRTRIVHRDIKASNILLDKEFNARVSDFGLARLLKDGDTHLSTRVAGTFGYLAPEYALRGKLTE-KADVYSFGI
 .   .|..|  .  ......|.|  |. .|.|||.| .|||||.  .  ..||||||.|        | . ||  |.|||     . .  |.|..|.|.
PFPE-HARFY--MYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LLLEILSGRSSIDFELPPEKSFLLEWAWELYEEGQWLDLVDEKLPPETCPKEELQRVMTVSLICTQGAPSARPAMSRVVAMLLGDIAPTLDITRPGFLPD
.| | |.|.   .     .   ...                                                  |. .  ..  .       ||.    
ILYEMLCGYPPFP-----QMQMMFKKIG-----------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA

LK-------HAAL
|.       |  .
LQDEWDIKCHPWF
Kinase IRAK-Un_bf.AA TK 248-285 23 0.002073 6.44 In-house 439-486 (486) Show / Hide 
Range on Protein: 248-285
Range on HMM: 439-486/486
Sequence Identity: 23% (12 aa)

PPETCPK-------------EELQRVMTVSLICTQGAPSARPAMSRVVAML
.|. ||              ||....|   . | .  |. || .| .. .|
QPPHCPDWMRYRMHPPHCPPEEYYDLM---QQCWHYDPEDRPTFSQLHEQL