Gene IRAKa_c-2 (S.moellendorffii)

IRAKa_c-2

Species: S.moellendorffii
Alias: IRAKa_c-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKa

Sequence

Name Sequence Type Origin Length Description Download
IRAKa_c-2.AA Protein None 757 None Fasta, JSON
IRAKa_c-2.NA RNA None 2274 None Fasta, JSON
IRAKa_c-2.kin_dom Protein Kinase Domain None 202 None Fasta, JSON

Protein domain

Protein domains of IRAKa_c-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAKa_c-2.AA TKL 448-711 22 4.4e-65 222.53 In-house 1-364 (364) Show / Hide 
Range on Protein: 448-711
Range on HMM: 1-364/364
Sequence Identity: 22% (86 aa)

LGKGAFGTVYKGVLEN---------GQAVAIKRAST----SSTRSS-----------------------ELFEKELQLLTRTHHSCLVNLVGYCMEEK--
.|.|.||.||||.. .         |. ||.|. ..    ..|..|                       . .|.|. .. |..|  .| ..|||....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------------LLVFEFMSRGSLYDNIFARSGPSAGLQWICRIKLAAQAARGLEYLHKYAC-----PPIIHRDVKSANILLDDEWN------------
              .| |....|||....           |  |...| ..|||..|||         ||||||| ||.|||.|. |.            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AHVSDFGLSLFGPLGSATHLS----------------NMTIVGTPGYLDPEYGFFM----------------KLTTKSDVYSFGVVLLELLSGQKPVD
  . ..||||| |    .    .                .||..|||... ||    .                . ..|.||||||.|| |.|....| .
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

--HFRPVQ------NIVIWAKELLNDDTLH-----QLFDPALAVPEMPEPLYRAAKLALECTDVRGKMRPSMTNVAKSL
  ...|..       . ... .  .  ..       .     . .  |  . . .||. .| |   . |||.. . | |
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH---K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKa_c-2.AA IRAK 442-645 36 8.7e-59 201.62 In-house 1-225 (317) Show / Hide 
Range on Protein: 442-645
Range on HMM: 1-225/317
Sequence Identity: 36% (81 aa)

YSEEMVLGKGAFGTVYKGVLENGQ-AVAIK----RASTSSTRSSELFEK---ELQLLTRTHHSCLVNLVGYCMEEKL--LVFEFMSRGSLYDNIFARSG-
.... ..|.|.||.||.|.. |    .|.|     |..| . . . |     ||....| .|  .| | ||| |.    ||...|. ||| |   .. | 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-PSAGLQWICRIKLAAQAARGLEYLHKYA-CPPIIHRDVKSANILLDDEWNAHVSDFGLSLFG-PLG--SATHL---SNMTIVGTPGYLDPEYGF--FMK
 |   | |. |.. .  .|.|...||    | ||||.|.||||||||.  ..  .||||  || | .   .. .      ...||  |. ||.    . .
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTTKSDVYSFGVVLLELLSGQKPVD
||.|.||||||.||||.|.|...|.
LTKKTDVYSFGIVLLEVLTGCRAVY
Kinase IRAKa_c-2.AA LRRK 442-647 25 3e-44 153.34 In-house 1-286 (351) Show / Hide 
Range on Protein: 442-647
Range on HMM: 1-286/351
Sequence Identity: 25% (75 aa)

YSEEMVLGKGAFG-TVYKGVLEN---------------------------GQAVAIKRASTS----------------------------------STRS
  .|  .|.|.|| .||.. ...                           .| ||||   .                                   ..|.
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

SELFEKELQLLTRTHHSCLVNLVGYCMEEKLLVFEFMSRGSLYDNIFARSGPS-----AGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILL
  .| .|. .. . .|...|.|.|.|..   .| |... |.||. .....  .     | . |  ..|.| | |.|.||||. . ||||||| || ||||
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNILL

---D---------DEWNAHVSDFGLSL-FGPLGSA-THLSNMTIVGTPGYLDPEYGFFM---KLTTKSDVYSFGVVLLELLSGQ-KPVDHF
   .         .. .|...|||.|  | ..... .    .. ||.||.. ||   ..     |.|.|.||||..| |||..|  | |..
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVA----KGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEH
Kinase IRAKa_c-2.AA TKL-Unique 447-643 32 2.9e-41 143.28 In-house 4-233 (290) Show / Hide 
Range on Protein: 447-643
Range on HMM: 4-233/290
Sequence Identity: 32% (76 aa)

VLGKGAFGTVYKGVLENGQAVAIKRAST---SSTRSSELFEKELQLLTRTH-HSCLVNLVGYCM----EEK--LLVFEFMSRGSLYDNIF---ARS---G
..| |..|.||||.  .|  ||||. .    || .... ||.|. .. . | |  .| ..||||     ..   .| |....|||||..      .    
KIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

PSAGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDE-----WNAHVSDFGLSLFGPLGSATHLSNM------TIVGTPGYLDPEYGFFM
..  | .  |.|.| ..|.|..||| .  | ||||| || |.|.| .     ||. ..||||| |    ... ...       | .|.. .. ||  . |
NNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV-LRM

---KLTTKSDVYSFGVVLLELLSGQK------P
   . ..||||||||.|| |.....       |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase IRAKa_c-2.AA Pkinase 442-641 28 2.3e-38 136.72 Pfam 1-209 (293) Show / Hide 
Range on Protein: 442-641
Range on HMM: 1-209/293
Sequence Identity: 28% (61 aa)

YSEEMVLGKGAFGTVYKGVLENGQA-VAIKRASTSSTRSSELFEK----ELQLLTRTHHSCLVNLVGYCMEEKLLV--FEFMSRG----SLYDNIF-ARS
|  . ..|.|.||.|||..  . .  ||.|. . ....|... ..    |.|.. | .| . | | ....... .   .|..  |    .|.| |   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPSAGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNA----HVSDFGLSLFGPLGSATHLSNMTIVGTPGYLDPEYGF-FMKLTTK
|.   ...   .. . | .|||||.|.     |||||.|..|||.|.. .     ...||||. .          ..|..|||.|. ||      . ..|
GCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

SDVYSFGVVLLELLSGQ
.|..|.|..| |.|.|.
VDMWSCGCILYEMLCGR
Kinase IRAKa_c-2.AA MLK 442-643 29 9e-37 125.12 In-house 1-235 (291) Show / Hide 
Range on Protein: 442-643
Range on HMM: 1-235/291
Sequence Identity: 29% (70 aa)

YSEEMVLGKGAFGTVYKGVLENGQ----AVAIKRAST------SSTRSSELFEKELQLLTRTHHSC----LVNLVGYCMEE-K--LLVFEFMSRGSLYDN
  .. ..|.|.|| |.||.  |       ||.||. .      ..  ... ||.|  .| .  |       . ..| | .. .  ..| |... ||||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IFA-RSGPS---------AGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDD------EWNAHVSDFGLSLFGPLGSATHLSNMTI-VGT
. . ||...         .       .. | | |||..|||. | .|||||| || |||.|.      . .. ..|||.| .    . .. .||.   ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD---WHQMC-TNMMSNAGT

PGYLDPEY---GFFMKLTTKSDVYSFGVVLLELLSGQKP
. .  ||        | . |.||.|.|||| |.|... |
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAKa_c-2.AA TK 442-643 17 1.1e-36 119.99 In-house 1-394 (486) Show / Hide 
Range on Protein: 442-643
Range on HMM: 1-394/486
Sequence Identity: 17% (68 aa)

YSEEMVLGKGAFG---TVYKGVLENG--------------------------QAVAIKRASTSSTRSSELFEK-----------------ELQLLT--RT
   . .||.|.||   .|||| ....                          . ||.|     .. |.| |.                  |....     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHSCLVNLVGYCMEEK--------------LLVFEFMSRGS----LYDNIFARSGPSAG-----------------------------------------
||  .|.|.|.|....              ..| |.|. |.    | |   .....                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LQWICRIKLAAQAARGLEYLHKYAC---PPIIHRDVKSANILLDDEWN-----------AHVSDFGLS-
                               |   ...  ..|.|.|.||||.  |   . ..|||.   |.|.... .           . ..||||| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LFGPLGSATHLSNMTIVGTPG-------------------------YLDPEYGF---------FMKLTTKSDVYSFGVVLLELLS-GQKP
     |   ..| .    ..  ||..                         .. ||  .         . | ||||||.||||.. |... ||.|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase IRAKa_c-2.AA S_TKc 442-715 24 2.4e-34 121.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 442-715
Range on HMM: 1-231/231
Sequence Identity: 24% (71 aa)

YSEEMVLGKGAFGTVYKGVLEN-GQAVAIKRASTSSTRSSELFEKELQLLTRTHHSCLVNLVGYCM-EEKLLVFEFMSR--GSLYDNIFARSGPSAG--L
|    ..||||||.|||..  . |. ||||. .       | ...|.|.| . ||  .|.| ...  ..  .|.|...   |.|.| |  | ..  .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLGSATHLSNMTIVGTPGYLDPEYGFFMKLTT-KSDVYSFGVVL
      ....| ...|||.|.     |||||.| .|||||.  .  ..||||. .           .|..||| |. ||     . .. |.|..|.|..|
PE-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LELLSGQKPVDHFRPVQNIVIWAKELLNDDTLHQLFDPALAVPEMPEPLYRAAKLALECTDVRGKMRPSMTNVAK-----SLEDIL
 |.|.|. | .      ..    | ..                        |  .   | ..  . ||.   . .      .   .
YEMLCGYPPFP------QMQMMFKKIG---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKa_c-2.AA Dicty4 442-655 33 3.9e-34 111.38 In-house 1-229 (277) Show / Hide 
Range on Protein: 442-655
Range on HMM: 1-229/277
Sequence Identity: 33% (79 aa)

YSEEMVLGKGAFGTVYKGVLENGQAVAIKRA--STSSTRSSEL--FEKELQLLTRTHHSCLVNLVGYCM------EEKLLVFEFMSRGSLYDNIFA---R
.  |  .|||.||.||||    |..||.| .       ....|  | ||  ..    |  .. . |.|       .. . | |.|..|.||  . .    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

SGPSAGLQWICRIK---LAAQAARGLEYLHKYAC--PPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLGSATHLSNMTIVGTPGYLDPEYGFFMKLTT
  .|  |.|. ...   .|  ||||. .||   |  | ||||| ||.|.| |. |.. |.|||||     ..      || .|||..  ||   .   . 
QQQSIKLDWPLIKRAMRMAFDAARGMNWLH---CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

KSDVYSFGVVLLELLSGQKPVD-HFRPVQNIVI
|.|||||| || |.| .| |   |..|  ..|.
KADVYSFGIVLWEILTRQEPYQKHHMPYMQFVR
Kinase IRAKa_c-2.AA RIPK 448-643 25 2.8e-30 100.38 In-house 1-227 (290) Show / Hide 
Range on Protein: 448-643
Range on HMM: 1-227/290
Sequence Identity: 25% (58 aa)

LGKGAFGTVYKGVLENGQAVAIKRASTSSTRS-------SELFEKELQLLTRTHHSCLVNLVGYCMEE--------KLLVFEFMSRGSLYDNIFARSG-P
.|.|.||.|.| .      ...| ....  .        ..    | . . .  ..  | . | | .|          .| |.|  ||| .   ...   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

SAGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLGSATH--------LSNMTIV--GTPGYLDPEYGF--FM
   . |  |  .  . ..|  |||    ||||||| | .|||.| . .. ..||||. .    . .         .|       ||  |..||  .    
HHPDPWPLRCRMIHEISCGMCYLHSMN-PPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

KL----TTKSDVYSFGVVLLELLSGQKP
|     |.|.|||||..|. |.|.. .|
KPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase IRAKa_c-2.AA Dicty4-Unclassified 445-643 32 3e-30 100.76 In-house 4-207 (263) Show / Hide 
Range on Protein: 445-643
Range on HMM: 4-207/263
Sequence Identity: 32% (69 aa)

EMVLGKGAFGTVYKGVLENGQAVAIKRASTSSTRSS----ELFEKELQLLTRTHHSCLVNLVGYCMEE------KLLVFEFMSRGSLYDNIF---ARSGP
   .|||.|  |.||.   |  ||.|     . .      . | ||  .|    |  || . |||.           | ||| .| |   |    .    
DQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

SAGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLGSATHLSNMTIVG-TPGYLDPEYGFFMKLTTKSDVYSF
.  |     || |   |.|. .||      .||||.||.|||.|   |. . |||.|            ||| .. ||    ||       . ||||||.
PIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISRV-----IDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSY

GVVLLELLSGQKP
...| ||. |  |
AMMLYELATGDEP
Kinase IRAKa_c-2.AA STE 442-641 23 1.1e-28 98.43 In-house 1-265 (359) Show / Hide 
Range on Protein: 442-641
Range on HMM: 1-265/359
Sequence Identity: 23% (64 aa)

YSEEMVLGKGAFGTVYKGVLEN----------------GQAVAIKRASTSST-----------------RSSELFEKELQLLTRTH--HSCLVNLVGYCM
.    ..||||||||||..  .                |. .|||. . ..                     . ..||.... . .  |   |.  |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

---------EEKLLVFEFMSRGSLYDNIFARSGPSAG------------LQWICRIKLAAQAARG-LEYLHKYACPPIIHRDVKSANILLDDEWNAHVSD
         .|  .. |.|. ||| | |  . |.  .             ..|..|  . |  .| |.|||.     |||||.|.|||||     .  .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYI--CRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCD

FGLSL-FGPLGS------------ATHLSNMTIVGTPGYLDPEY--GFFMK----LTTKSDVYSFGVVLLELLSGQ
||..  . . ..             .   . |.|||| .  ||   .   .     .||.|..|.| ...|.. |.
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase IRAKa_c-2.AA Pkinase_Tyr 442-588 27 1.1e-27 94.34 Pfam 1-158 (270) Show / Hide 
Range on Protein: 442-588
Range on HMM: 1-158/270
Sequence Identity: 27% (45 aa)

YSEEMVLGKGAFGTVYKGVLE-----NGQAVAIKRASTSSTRS---SELFEKELQLLTRT-HHSCLVNLVGYCM--EEK---LLVFEFMSRGSLYDNIFA
 .   .||.||||.||||..      ... ||.|    ... .   .| | .|.....   ||  .|.|.| |.  .|    ..|.|.|  |.|.|   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R--SGPSAGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLS
.  ....  ...   .. ..| |.|.|||.      .||||.   |.|....  . ..||||.
HREDKQPLTMKD--LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLA
Kinase IRAKa_c-2.AA TyrKc 442-711 24 6.6e-25 89.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 442-711
Range on HMM: 1-280/280
Sequence Identity: 24% (75 aa)

YSEEMVLGKGAFGTVYKGVLENGQAVAIKRASTSSTRSSELFEKELQLLTRT--HHSCLVNLVGYCM---------EEKLLVFEFMSRGSLYDNIFARSG
 . . .|| ||||.||||..   . ||.|    ..    | | .|......   || ..|.|.|.|.         |  ..|.|.|. |.| | . .. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

PSAGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLG-------SATH-----LSN--MTIVGTPGYLDPEYG
    |..   .. . |.|.| ||||.    ..||||    |.|....  . .|||||| ..  .       .  .      ..  . |  ..    ||  
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA----PECI

FFMKLTTKSDVYSFGVVLLELLS-GQKPVDH---FRPVQNIVIWAKELLNDDTLHQLFD--PALAVPEMPEPLYRAAKLALECTDVRGKMRPSMTNVAKS
.. | ||||||.||||.. |... ||.|        .. |. . .. . . . . |  .  | .. ...|. .|   .. ..| .   ..||..... . 
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEY-VKQGYRMPQPPNDYP-MSFVCCPDEMY---QIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase IRAKa_c-2.AA Pkinase_Tyr 617-643 50 1e-06 23.24 Pfam 187-214 (270) Show / Hide 
Range on Protein: 617-643
Range on HMM: 187-214/270
Sequence Identity: 50% (14 aa)

FFMKLTTKSDVYSFGVVLLELLS-GQKP
...| ||||||.||||.. |... |..|
NYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase IRAKa_c-2.AA IRAK 689-711 30 0.006496 6.36 In-house 295-317 (317) Show / Hide 
Range on Protein: 689-711
Range on HMM: 295-317/317
Sequence Identity: 30% (7 aa)

LALECTDVRGKMRPSMTNVAKSL
.|..|.  | . |..|. | ..|
CACCCGHHRANRRCDMAWVMQQL