Gene IRAKg_d-2 (S.moellendorffii)

IRAKg_d-2

Species: S.moellendorffii
Alias: IRAKg_d-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKg

Sequence

Name Sequence Type Origin Length Description Download
IRAKg_d-2.AA Protein None 842 None Fasta, JSON
IRAKg_d-2.NA RNA None 2529 None Fasta, JSON
IRAKg_d-2.kin_dom Protein Kinase Domain None 273 None Fasta, JSON

Protein domain

Protein domains of IRAKg_d-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKg_d-2.AA B_lectin 77-184 30 1.6e-19 68.64 Pfam 1-137 (137) Show / Hide 
Range on Protein: 77-184
Range on HMM: 1-137/137
Sequence Identity: 30% (42 aa)

PNTVVWSAMSNDTGGFPI-GLI--KGDQLVFQI-DGRLVLTSNAAG--I--IWGT--STSTLG---VIKALLQENGNLQLLT-SN--GVPVWQS--FERP
. ||||.|  .  .| |. .     . .|..|  || |||. ...|  .  .| |  .||. |      | .|..||| |.. .|  . ..|||  |. |
NQTVVWVANRDL-TGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHP

TDTLLPYQQL-------IGNTR---LVSSNRKY--DLR
|||.|| . |       |. ..   |.|.      | .
TDTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTNYDPS
B_lectin IRAKg_d-2.AA B_lectin 36-158 25 8.6e-11 43.09 SMART 1-126 (126) Show / Hide 
Range on Protein: 36-158
Range on HMM: 1-126/126
Sequence Identity: 25% (35 aa)

IVRGEDPQTWITSPNATFS--AGFSHINHTFPLYSFSIWYTKM---PNTVVWSAMSNDTGGFPIGLIKG----DQLVFQIDGRLVLTSNAAGIIWGTSTS
     . || . |.| .|.  .||   .        .||| ..   . ||||.|    ..    .. ..      |..| || ||.      ..| ..|.
DNTLSSGQT-LVSGNSLFEFYLGFFTFIMQ---WCNGIWYKNISNKQRTVVWVAQP-NRD----NPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNTT

-TLGVIKALLQENGNLQLLTSN----GVPVWQSFERP
 . |.  | ||..||. .  ..    |  .||||. |
RNNGNYVAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
S_locus_glycop IRAKg_d-2.AA S_locus_glycop 263-325 31 2.8e-13 47.76 Pfam 55-117 (117) Show / Hide 
Range on Protein: 263-325
Range on HMM: 55-117/117
Sequence Identity: 31% (20 aa)

RLTLDDDGNLRIYTLDEIKNRWLITWQAVLLECDIFGKCGRFGICTYRPTATCICPPGFHPTN
|.|.. .| | ..|  .  ..|   | |   .||. . ||..|.|    . .| | .||.| |
RFTMSSEGYLQRFTWNPNSQDWNLFWYAPKDQCDYYRRCGPYGYCDMNTSPMCNCIKGFVPKN
EGF IRAKg_d-2.AA EGF 294-334 25 0.000329 21.23 SMART 1-32 (32) Show / Hide 
Range on Protein: 294-334
Range on HMM: 1-32/32
Sequence Identity: 25% (12 aa)

ECDIFGKCGRF-----GICTYRPTATCICP-PGFHPTNASDPSQDCV
||.    |.       |.|.   . || || ||..          |.
ECA---PCHHGGCEQHGTCI---SYTC-CPGPGYTG--------RCE
B_lectin IRAKg_d-2.AA B_lectin 263-275 50 9.933461 0.64 Pfam 27-40 (137) Show / Hide 
Range on Protein: 263-275
Range on HMM: 27-40/137
Sequence Identity: 50% (7 aa)

RLTLDD-DGNLRIY
.||... |||| .|
TLTMQNRDGNLVLY
PAN_AP IRAKg_d-2.AA PAN_AP 351-433 15 0.000613 17.15 SMART 1-85 (85) Show / Hide 
Range on Protein: 351-433
Range on HMM: 1-85/85
Sequence Identity: 15% (15 aa)

PRNFKMIQLVRTDFQYNDYNSHP-----LPNPSSQEDCIQRCLRECECLGAAFQMGGAGICWLKGLDPSGLFNGKQ------SVDVDNVFFLKV
.. . .. . ..       .|.           | |.| |.||..|.| ....     . | |   . | |.. .|        ..  ... |.
CCDDCFVRMPNMKL-----FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN--TKGCHLWS-WDSHLGDPRQFKRFMKFPNQGVDYYEKN
Kinase IRAKg_d-2.AA TKL 536-730 25 8.5e-65 221.58 In-house 1-289 (364) Show / Hide 
Range on Protein: 536-730
Range on HMM: 1-289/364
Sequence Identity: 25% (75 aa)

LGSGGFGTVYKGRLPN---------GTLVAVKELEM----------------------------AMQADKQFQAEVKTLGKIHHINLVRLLGYCYEDNR-
.||||||.||||.. .         |. |||| . .                            |... ...  |.. . ...| |.|...||| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KLLVYEYMPNGS-LEKLLFLNDTEHFCGWASRFNIALGIARGITYLHDEC-----QECILHCDIKPQNILLDESFI------------
              .|.||.|.|| |. |.          |  |...||.||||. ||| .         |.|.|.|..|||.|| .             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PKVADFGLAKLMKRERELSVTT------------------VRGTRGYLAPEWISNL----------------PITTKVDVYSFGMVLLEIISGREKY
  .|..||||.. |... . . |                   ..|| ...||| . .                 . ..|.||||||.|| ||..... |
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY
Kinase IRAKg_d-2.AA IRAK 528-805 34 1.9e-63 217.11 In-house 1-317 (317) Show / Hide 
Range on Protein: 528-805
Range on HMM: 1-317/317
Sequence Identity: 34% (112 aa)

FTDNFYDRLGSGGFGTVYKGRLPNGT-LVAVKEL-EMAM----QADKQFQA---EVKTLGKIHHINLVRLLGYCYEDNRKLLVYEYMPNGSLEKLLFLND
|  ..  |.|.||||.||.|.. | |  .||| | |||.    . ...||.   |.|.. ...| |.| |.|||.|     |||.||||||||  |   |
FHKDN--RIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQD

TEHF---CGWASRFNIALGIARGITYLHDEC-QECILHCDIKPQNILLDESFIPKVADFGLAKL-----MKREREL---SVTTVRGTRGYLAPEWIS--N
.        |  |. |..|.|.|| .||.      | | |||. |||||. | || .||||.        |   ..    . .||||  |..|| |    
GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQ

LPITTKVDVYSFGMVLLEIISGR---------EKYLMTISAINSENNRW---CLS---------DWAYNMYQAGDLESIIDKKLVREDVDLVQFKRLLKV
  .|.|.|||||| ||||...|.          .||...   . |  .    |.|          ||    .. . |  ||..   .... .  | .. .
GQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWA-APRRMQIYEKFIDHRM--PPCPPNMEKEMCQC

ALWCIQHDANARPSMGKVVQMM
|. |  | || |..| .|.| .
ACCCGHHRANRRCDMAWVMQQL
Kinase IRAKg_d-2.AA Pkinase 531-805 21 1.1e-46 166.19 Pfam 2-293 (293) Show / Hide 
Range on Protein: 531-805
Range on HMM: 2-293/293
Sequence Identity: 21% (71 aa)

NFYDRLGSGGFGTVYKGRLPNG-TLVAVKELEMAMQADKQFQA-----EVKTLGKIHHINLVRLLGYCYEDNRKLLVYEYMPNG----SLEKLLF--LND
 .  ..|||.||.|||..  .   .||||...   . ... |.     |.. . ...| | |||.........  .| ||...|    .|  ..    . 
HIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHG

TEHFCGWASRFNIALGIARGITYLHDECQECILHCDIKPQNILLDESFIP----KVADFGLAKLM-KRERELSVTTVRGTRGYLAPEWIS-NLPITTKVD
.     .    .... |.||. |.|..    |.|.|.||.|||.|.   .    |..||||||..     .   ||. ||..|.|||.|  . ....|||
CFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSFGMVLLEIISGREKYLMTISAINSENNRWCLSDWAYNMYQAG------DLESIIDKKLVREDVDLVQF-----------------------KRLLKV
..|.| .| | ..||                          ..        |   .|.... . ...   .                       . ....
MWSCGCILYEMLCGR------------------------PPFPGHCWHDNHDQMQMICRIM-GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF

ALWCIQHDANARPSMGKVVQM--M
  ||.. | . ||.   ..|   .
IKWCLCKDPKKRPTAEQILQHPWF
Kinase IRAKg_d-2.AA TKL-Unique 532-726 31 6.6e-45 155.5 In-house 1-224 (290) Show / Hide 
Range on Protein: 532-726
Range on HMM: 1-224/290
Sequence Identity: 31% (71 aa)

FYDRLGSGGFGTVYKGRLPNGTLVAVKELEM-AMQADK--Q-FQAEVKTLGKIH-HINLVRLLGYCY----EDNRKLLVYEYMPNGSLEKLLF----LN-
|   .|.||.|.||||   .|. ||.| ..  . .  .  | |  ||... |.| |.|.|.. |||       ..  .| ||.| ||| ..|     .| 
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--DTEHFCGWASRFNIALGIARGITYLHDECQECILHCDIKPQNILLDES-----FIPKVADFGLAKLMKRERELSVT--------TVRGTRGYLAPEWI
    ..   .. | ..|. ||.|  ||| .    |.|.|.|..|.|.|.      .  |..||||.|. ... . ...        |. |.  ..||| .
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

SN--LPITTKVDVYSFGMVLLEIISG
..    ...|.||||||.|| ||...
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAKg_d-2.AA Dicty4 531-723 36 1.3e-44 146.77 In-house 2-210 (277) Show / Hide 
Range on Protein: 531-723
Range on HMM: 2-210/277
Sequence Identity: 36% (77 aa)

NFYDRLGSGGFGTVYKGRLPNGTLVAVKELEMAMQAD-----KQFQAEVKTLGKIHHINLVRLLGYCY----EDNRKLLVYEYMPNGSLEKLLFLND---
|. .|.|.|.||.||||.   |. |||| |    | .     . | .||. ..|| | |.. ..|.|     .  . . | |||| |.|..|  |.|   
NIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSL--LHDKPS

---TEHFCGWASRFN---IALGIARGITYLHDECQECILHCDIKPQNILLDESFIPKVADFGLAKLMKRERELSV--TTVRGTRGYLAPEWISNLPITTK
    .    |  .     .|. .|||...|| .|   |.| |.|. |.| |...  ||.||||...||.. ...   .|. || .. |||   . | . |
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEK

VDVYSFGMVLLEI
.||||||.|| ||
ADVYSFGIVLWEI
Kinase IRAKg_d-2.AA S_TKc 530-809 23 1.9e-40 141.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 530-809
Range on HMM: 1-231/231
Sequence Identity: 23% (70 aa)

DNFYDRLGSGGFGTVYKGRLPN-GTLVAVKELEMAMQADKQFQAEVKTLGKIHHINLVRLLGYCYEDNRKLLVYEYMPN--GSLEKLLFLNDTEH----F
  . . .|.|.||.|||.|  . | .||.|..       .... |.. | | || |.|.|...... ..  .| ||...  |.| ...  . ..     |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

CGWASRFNIALGIARGITYLHDECQECILHCDIKPQNILLDESFIPKVADFGLAKLMKRERELSVTTVRGTRGYLAPEWISNLPITT-KVDVYSFGMVLL
     || ..  |.... |.|   .  |.|.|.||.||||||    |..|||||...        ||. ||. |.||| .   . .. |.|..|.| .| 
PE-HARF-YMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EIISGREKYLMTISAINSENNRWCLSDWAYNMYQAGDLESIIDKKLVREDVDLVQFKRLLKVALWCIQHDANARPSMGKVVQ-----MMEDTI
| ..|.  .                           ... ...| .          . ..     | | | . ||.  .. |     ..   .
EMLCGYPPFP--------------------------QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKg_d-2.AA MLK 531-728 27 6e-40 136.28 In-house 2-234 (291) Show / Hide 
Range on Protein: 531-728
Range on HMM: 2-234/291
Sequence Identity: 27% (65 aa)

NFYDRLGSGGFGTVYKGRLPNGT----LVAVKELEM---AMQA----DKQFQAEVKTLGKIHHIN----LVRLLGYCYED-NRKLLVYEYMPNGSLEKLL
.|   .|||.|| |.|||  | .     ||||. .    ...     ...|. |.. | .. | |     ....| | .. .  ..| ||...|||  .|
QFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVL

FLNDTEHF-----------CGWASRFNIALGIARGITYLHDECQECILHCDIKPQNILLDE------SFIPKVADFGLAKLMKRERELSVTTVRGTRGYL
  .... .              .. .|.|| .|||. ||| . .  | | |.|..|||.||        . |..|||... ...      .  .||  . 
HGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWM

APEWI---SNLPITTKVDVYSFGMVLLEIISGRE
||| |    . . . |.||.|.|.|| |......
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREV
Kinase IRAKg_d-2.AA LISK 535-728 29 1.1e-38 123.12 In-house 1-237 (296) Show / Hide 
Range on Protein: 535-728
Range on HMM: 1-237/296
Sequence Identity: 29% (70 aa)

RLGSGGFGTVYKGRLP-NGTLVAVKELEM------AMQADKQFQAEVKTLGKIHHINLVRLLGYCYE-DNRKLLVYEYMPNGSLEKLLFLNDT-EHFCGW
 .|.|.|| ||||..   |. .|.|...          . | .. ||... .. | | |.  | ||. | .  .| ||.  | |. .|. .|       |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

ASRFNIALGIARGITYLHDECQECILHCDIKPQNILLDES----FIPKVADFGLAKLMKRER----------------------------------ELSV
  | .|||.||.| .|||.    .|.| | | .|.|..|.    .  ||.|||.|..|  |.                                    . 
PQRVKIALDIACGMSYLHS---MNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

TTVRGTRGYLAPEWISNLPITTKVDVYSFGMVLLEIISGRE
| . ||    ||| .     ....||.|||.||.||| ...
TIC-GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVK
Kinase IRAKg_d-2.AA STE 533-727 21 1.1e-35 123.47 In-house 1-265 (359) Show / Hide 
Range on Protein: 533-727
Range on HMM: 1-265/359
Sequence Identity: 21% (60 aa)

YDR---LGSGGFGTVYKGRLPN----------------GTLVAVKELEMAM------------------QADKQFQAEVKTLGKIH--HINLVRLLGYCY
...   .|.|.||||||..  .                |...|.|....                    .  .|.. |.|.. | .  | | |. .|...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------NRKLLVYEYMPNGSLEKLLF------LNDT----------EHFCGWASRFNIALGIARG-ITYLHDECQECILHCDIKPQNILLDESFIPK
 .       .   .. |||..|||....        ...          |.  ..     |.  | .|   |||.     | | ||||.||||      |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAY-----ICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VK

VADFGLAKLMKR---------------ERELSVTTVRGTRGYLAPEWISN------LPITTKVDVYSFGMVLLEIISGR
 .|||... .                  .    .|. ||  . ||| |..       . .||.|..|.| ...| . |.
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase IRAKg_d-2.AA Pkinase_Tyr 531-725 32 2.5e-34 116.87 Pfam 2-209 (270) Show / Hide 
Range on Protein: 531-725
Range on HMM: 2-209/270
Sequence Identity: 32% (70 aa)

NFYDRLGSGGFGTVYKGRLP-----NGTLVAVKEL-EMAMQAD---KQFQAEVKTLGKI-HHINLVRLLGYCYEDNRK---LLVYEYMPNGSLEKLLFLN
 |   ||.| ||.||||..      ... |||| | | ||. .   . | .|.|.. .. || |.|||.| |... .    ..| ||||.|.| . |  .
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

--DTEHFCGWASRFNIALGIARGITYLHDECQECILHCDIKPQNILLDESFIPKVADFGLAKLM-----K-RERELSVTTVRGTRGYLAPEWISNLPITT
  | ....      .... ||.|  ||..     . | |.   |.|..|... |..|||||...       | |. .   .. .    ||| |..   ||
REDKQPLTMKD-LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFTT

KVDVYSFGMVLLEIIS
| ||.||| .. ||..
KSDVWSFGVLMWEIFT
Kinase IRAKg_d-2.AA LRRK 520-727 23 7.3e-31 106.4 In-house 1-279 (351) Show / Hide 
Range on Protein: 520-727
Range on HMM: 1-279/351
Sequence Identity: 23% (69 aa)

FTYQQLQNFTDNFYDRLGSGGFG-TVYKGRLPN---------------------------GTLVAVKELEM-----------------------------
. ....          .|.|||| .||.... .                           .. ||.| ...                             
LKIEEQ----------IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDM

------AMQADKQFQAEVKTLGKIHHINLVRLLGYCYEDNRKLLVYEYMPNGSLEKLLFLND-TE-HFCG----WASRFNIALGIARGITYLHDECQE-C
      .. |   |. ||  . . .| |.| |.|.| .  .  .| ||.|.|.| ..|. .  .. ||      |  .  ||| ||.|. |||.  .   
DQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS--HNPP

ILHCDIKPQNILL---D---------ESFIPKVADFGLAKLMKRERELS--VTTVRGTRGYLAPEWIS---NLPITTKVDVYSFGMVLLEIISGR
|.|.| |. ||||   .         .  . |.||||.   |     ..  . .. |. |..||| .    .   |.|||.|||||.| |.....
IIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase IRAKg_d-2.AA TyrKc 530-805 23 7.2e-27 96.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 530-805
Range on HMM: 1-280/280
Sequence Identity: 23% (72 aa)

DNFYDRLGSGGFGTVYKGRLPNGTLVAVKELEMAMQADKQFQAEVKTLGKI--HHINLVRLLGYCYED-------NRKLLVYEYMPNGSLEKLLFLNDTE
  . . ||.| ||.||||..   . |||| |       . |  | . . |.  || |.|||.|.| ..          ..| ||||.|.| . |  .  .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

HFCGWASRFNIALGIARGITYLHDECQECILHCDIKPQNILLDESFIPKVADFGLAKLMKRE-------RELSVTTVRGTRG-----YLAPEWISNLPIT
    ..   .... ||.|  |||.    .. | |.   |.|..| .. |..||||..  . .          .... .|...      .||| |     |
--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

TKVDVYSFGMVLLEIIS-GREKYL------MTISAINSENNRWCLSDWAYNMYQAGDLESIIDKKLVREDVDLV----QFKRLLKVALWCIQHDANARPS
|| ||.||| .. || . | . |       |. . .             ..  ..|.   . .  .       .      . . .. ..| ..|.. ||.
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV-------------IEYVKQGYRMPQPPNDY-----P-MSFVCCPDEMYQIMKQCWHEDPEDRPT

MGKVVQMM
.  ... .
FSEIHECF
Kinase IRAKg_d-2.AA ULK 650-727 31 3.6e-20 67.16 In-house 151-253 (329) Show / Hide 
Range on Protein: 650-727
Range on HMM: 151-253/329
Sequence Identity: 31% (32 aa)

ILHCDIKPQNILLDESF------------IPKVADFGLAKLMK---RERELSVTTV-----RGTRGYLAPEWISNL----PIT-TKVDVYSFGMVLLEII
| |.||||||||... .            . |.||||.|| .     | .. .|.|     .||  | ||. ....    | .  |.|..|.|... |..
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

SGR
 |.
YGK
Kinase IRAKg_d-2.AA ULK 650-727 31 1.9e-19 65.74 In-house 147-249 (324) Show / Hide 
Range on Protein: 650-727
Range on HMM: 147-249/324
Sequence Identity: 31% (32 aa)

ILHCDIKPQNILLDESF------------IPKVADFGLAKLMK---RERELSVTTV-----RGTRGYLAPEWISNL----PIT-TKVDVYSFGMVLLEII
| |.||||||||. . .            . |.||||.||       |  .  |.|     .||  | ||. ....    | .  |.|..|.|... |..
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

SGR
 |.
YGK
Kinase IRAKg_d-2.AA ULK 531-614 24 1.1e-17 59.36 In-house 2-108 (324) Show / Hide 
Range on Protein: 531-614
Range on HMM: 2-108/324
Sequence Identity: 24% (26 aa)

NFYDRLGSGGFG-TVYKGR-LPN---GTLVAVKELE---MAMQADK--------QFQAEVKTLGKIH---HIN--LVRLLGYCYED--NRKLLVYEYMPN
.  ..||.| || .|||||   .   . .||.|  .   | ..  .        ... |.... |..   | |   |.|. .....  |   ...|| . 
CLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNG

GSLEKLL
| ||...
GDLEQYI
Kinase IRAKg_d-2.AA ULK 531-614 24 3.3e-16 53.16 In-house 2-111 (329) Show / Hide 
Range on Protein: 531-614
Range on HMM: 2-111/329
Sequence Identity: 24% (27 aa)

NFYDRLGSGGFGTVYKGR-LPN----GTLVAVKELE---MAMQADK--------QFQAEVKTLGKIH----HIN----LVRLLGYCYED--NRKLLVYEY
.  ..||.| ||.|||||   .    . .||.| ..   | .. .         ... |.|.. |..    |.|     |.|. .....  |   ...||
CLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEY

MPNGSLEKLL
 . | ||...
CNGGDLEQYI
Kinase IRAKg_d-2.AA TKL 778-805 25 0.000138 12.45 In-house 337-364 (364) Show / Hide 
Range on Protein: 778-805
Range on HMM: 337-364/364
Sequence Identity: 25% (7 aa)

KRLLKVALWCIQHDANARPSMGKVVQMM
... | . .| .||...|||. .... .
PSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKg_d-2.AA LRRK 775-807 21 0.000494 10.14 In-house 319-351 (351) Show / Hide 
Range on Protein: 775-807
Range on HMM: 319-351/351
Sequence Identity: 21% (7 aa)

VQFKRLLKVALWCIQHDANARPSMGKVVQMMED
... ....   .| ||| . ||.. ..|. ...
QPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKg_d-2.AA LISK 780-805 30 0.026662 3.05 In-house 271-296 (296) Show / Hide 
Range on Protein: 780-805
Range on HMM: 271-296/296
Sequence Identity: 30% (8 aa)

LLKVALWCIQHDANARPSMGKVVQMM
.|.....|.  | . |||  ..||  
FLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase IRAKg_d-2.AA Dicty4 786-807 37 0.04906 2.78 In-house 254-277 (277) Show / Hide 
Range on Protein: 786-807
Range on HMM: 254-277/277
Sequence Identity: 37% (9 aa)

WCIQHDANARPSMGKVVQM--MED
||  || . |||.  ..|   .| 
WCWDHDPQHRPSFEEIIQRRILEH
Kinase IRAKg_d-2.AA Pkinase_Tyr 785-805 19 0.969059 3.13 Pfam 250-270 (270) Show / Hide 
Range on Protein: 785-805
Range on HMM: 250-270/270
Sequence Identity: 19% (4 aa)

LWCIQHDANARPSMGKVVQMM
. | ..|.. ||..  .....
KQCWHYDPEDRPTFSEIHEQL