Gene IRAKg_n-2 (S.moellendorffii)

IRAKg_n-2

Species: S.moellendorffii
Alias: IRAKg_n-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKg

Sequence

Name Sequence Type Origin Length Description Download
IRAKg_n-2.AA Protein None 836 None Fasta, JSON
IRAKg_n-2.NA RNA None 2511 None Fasta, JSON
IRAKg_n-2.kin_dom Protein Kinase Domain None 195 None Fasta, JSON

Protein domain

Protein domains of IRAKg_n-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKg_n-2.AA B_lectin 71-162 32 4e-18 63.85 Pfam 1-109 (137) Show / Hide 
Range on Protein: 71-162
Range on HMM: 1-109/137
Sequence Identity: 32% (36 aa)

PNTVIWSAMSNDTGGSPIGLIKC----DQLAFQT-DGRLILTSKAAG--I--VWGT--STTTLS---VTKALLQENGNLELL-ASN--GVPAWQS--FDR
. || |.|  .  .|.|.   .      .| .|. || |.|.  ..|  .  || |  .|.. .    . | .|..||| |.  .|  . . |||  || 
NQTVVWVANRDL-TGNPV-TDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDH

PTDTILPDQQL
||||.|| . |
PTDTWLPGMKL
B_lectin IRAKg_n-2.AA B_lectin 27-152 24 4.2e-10 40.81 SMART 1-126 (126) Show / Hide 
Range on Protein: 27-152
Range on HMM: 1-126/126
Sequence Identity: 24% (34 aa)

TTTIVRGEDLQPWITSLKATFCAGFRHLDSKSSLYSFSIWYTKM---PNTVIWSAMSNDTGGSPIGLIKC----DQLAFQTDGRLILTSKAAGIVWGTST
. |.  |. |    .. .  | .||  ...       .||| ..   . ||.|.|          .. .       | .|.|| |..      .|| ..|
DNTLSSGQTLVSGNSLFE--FYLGFFTFIMQ---WCNGIWYKNISNKQRTVVWVAQP-----NRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNT

T-TLSVTKALLQENGNLELLASN----GVPAWQSFDRP
| . ... | ||..||. .  ..    |   ||||| |
TRNNGNYVAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
S_locus_glycop IRAKg_n-2.AA S_locus_glycop 259-321 30 2.1e-13 48.21 Pfam 55-117 (117) Show / Hide 
Range on Protein: 259-321
Range on HMM: 55-117/117
Sequence Identity: 30% (19 aa)

RLTVDDDGNLRIYTLDEINKRWIITWQAVLLECNIFGKCGRFGICTYRPTATCTCPPGFHPTN
|.|.. .| | ..|  . ...|.  | |   .| . . ||..|.|    . .|.| .||.| |
RFTMSSEGYLQRFTWNPNSQDWNLFWYAPKDQCDYYRRCGPYGYCDMNTSPMCNCIKGFVPKN
Kinase IRAKg_n-2.AA TKL 529-798 20 5.1e-69 235.61 In-house 1-364 (364) Show / Hide 
Range on Protein: 529-798
Range on HMM: 1-364/364
Sequence Identity: 20% (83 aa)

LGSGGFGTVYKGRLLN---------GTLVAVKELEM----------------------------AMQADKQFQTEVETLGKIHHINLVRLLGYCYEDNR-
.||||||.||||.. .         |. |||| . .                            |... ...  |.  . ...| |.|...||| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KLLVYEYMPNGS-LEKLLFLDDAKHFCSWANRFSIALGIARGITYLHDEC-----QECILHCDIKPQNILLDESFC------------
              .|.||.|.|| |. |.          |  |...||.||||. ||| .         |.|.|.|..|||.|| .             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PKVADFGLAKLMKRERALSVTT------------------VRGTRGYLAPEWISNL----------------PITTKVDVYSFGMVLLEIISGREKYI
  .|..||||.. |...   . |                   ..|| ...||| . .                 . ..|.||||||.|| ||.....   
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

MTISAINSENSRWCLSDWAYNMYQAGDMESIVDK-------KLVGEEV-----------------DFMQFKRLLKVALWCIQHDAHARPSMGKVVQMM
                      |.  ......         ..|...                       ... | . .| .||...|||. .... .
---------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKg_n-2.AA IRAK 521-720 41 1.4e-62 214.27 In-house 1-221 (317) Show / Hide 
Range on Protein: 521-720
Range on HMM: 1-221/317
Sequence Identity: 41% (92 aa)

FTDNFCDKLGSGGFGTVYKGRLLNGT-LVAVKEL-EMAM----QADKQFQT---EVETLGKIHHINLVRLLGYCYEDNRKLLVYEYMPNGSLEKLLFLDD
|  ..  ..|.||||.||.|.. | |  .||| | |||.    . ...||.   |.... ...| |.| |.|||.|     |||.||||||||  |   |
FHKDN--RIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQD

AKHF---CSWANRFSIALGIARGITYLHDEC-QECILHCDIKPQNILLDESFCPKVADFGLAKLM----KRERALS----VTTVRGTRGYLAPEWIS--N
.       ||  |.||..|.|.|| .||.      | | |||. |||||. | || .||||.        .|.. .    . .||||  |..|| |    
GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQ

LPITTKVDVYSFGMVLLEIISGR
  .|.|.|||||| ||||...|.
GQLTKKTDVYSFGIVLLEVLTGC
Kinase IRAKg_n-2.AA Pkinase 528-798 23 2.5e-48 171.68 Pfam 6-293 (293) Show / Hide 
Range on Protein: 528-798
Range on HMM: 6-293/293
Sequence Identity: 23% (76 aa)

KLGSGGFGTVYKGRLLNG-TLVAVKELEMAMQADKQFQT-----EVETLGKIHHINLVRLLGYCYEDNRKLLVYEYMPNG----SLEKLLFLDDAKHF-C
|.|||.||.|||..  .   .||||...   . ... ||     |.. . ...| | |||.........  .| ||...|    .|  ..  .. . |  
KIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYF

SWANRFSIALGIARGITYLHDECQECILHCDIKPQNILLDESFCP----KVADFGLAKLMKRERALSVTTVRGTRGYLAPEWIS-NLPITTKVDVYSFGM
|.    .... |.||. |.|..    |.|.|.||.|||.|.   .    |..||||||...  .    ||. ||..|.|||.|  . ....|||..|.| 
SEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGC

VLLEIISGREKYIMTISAINSENSRWCLSDWAYNMYQAG------DMESIVDKKLVGEEVDFMQF-----------------------KRLLKVALWCIQ
.| | ..||                          ..        |.  ...... | ...|  .                       . ....  ||..
ILYEMLCGR------------------------PPFPGHCWHDNHDQMQMICRIM-GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

HDAHARPSMGKVVQM--M
 | . ||.   ..|   .
KDPKKRPTAEQILQHPWF
Kinase IRAKg_n-2.AA TKL-Unique 525-719 31 6.8e-47 162.11 In-house 1-224 (290) Show / Hide 
Range on Protein: 525-719
Range on HMM: 1-224/290
Sequence Identity: 31% (71 aa)

FCDKLGSGGFGTVYKGRLLNGTLVAVKELEM-AMQADK--Q-FQTEVETLGKIH-HINLVRLLGYCY----EDNRKLLVYEYMPNGSLEKLLF----LD-
|  |.|.||.|.||||   .|. ||.| ..  . .  .  | |  || .. |.| |.|.|.. |||       ..  .| ||.| ||| ..|     .  
FWNKIGEGGYGQVYKG-KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--DAKHFCSWANRFSIALGIARGITYLHDECQECILHCDIKPQNILLDES-----FCPKVADFGLAKLMKRERALSVT--------TVRGTRGYLAPEWI
    ..  ....| ..|. ||.|  ||| .    |.|.|.|..|.|.|.      .  |..||||.|. ... . ...        |. |.  ..||| .
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

SN--LPITTKVDVYSFGMVLLEIISG
..    ...|.||||||.|| ||...
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAKg_n-2.AA Dicty4 524-716 35 8.1e-44 144.12 In-house 2-210 (277) Show / Hide 
Range on Protein: 524-716
Range on HMM: 2-210/277
Sequence Identity: 35% (76 aa)

NFCDKLGSGGFGTVYKGRLLNGTLVAVKELEMAMQAD-----KQFQTEVETLGKIHHINLVRLLGYCY----EDNRKLLVYEYMPNGSLEKLLFLD----
|. ...|.|.||.||||.   |. |||| |    | .     . |  ||. ..|| | |.. ..|.|     .  . . | |||| |.|..|| .|    
NIEQRIGKGSFGEVYKGT-WRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLL-HDKPSE

-DAKHFCSWANRFS---IALGIARGITYLHDECQECILHCDIKPQNILLDESFCPKVADFGLAKLMKRERALSV--TTVRGTRGYLAPEWISNLPITTKV
   .   .|  . .   .|. .|||...|| .|   |.| |.|. |.| |...  ||.||||...||..  ..   .|. || .. |||   . | . |.
QQQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGMVLLEI
||||||.|| ||
DVYSFGIVLWEI
Kinase IRAKg_n-2.AA LISK 528-721 29 1.2e-41 132.99 In-house 1-237 (296) Show / Hide 
Range on Protein: 528-721
Range on HMM: 1-237/296
Sequence Identity: 29% (71 aa)

KLGSGGFGTVYKGRLL-NGTLVAVKELEM------AMQADKQFQTEVETLGKIHHINLVRLLGYCYE-DNRKLLVYEYMPNGSLEKLLFLDDA-KHFCSW
..|.|.|| ||||...  |. .|.|...          . | .. ||... .. | | |.  | ||. | .  .| ||.  | |. .|.  |  |   .|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

ANRFSIALGIARGITYLHDECQECILHCDIKPQNILLDES----FCPKVADFGLAKLMKRER---------------------------------ALSVT
  | .|||.||.| .|||.    .|.| | | .|.|..|.    .  ||.|||.|..|  |.                                 . .  
PQRVKIALDIACGMSYLHS---MNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

TVRGTRGYLAPEWISNLPITTKVDVYSFGMVLLEIISGRE
|. ||    ||| .     ....||.|||.||.||| ...
TICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVK
Kinase IRAKg_n-2.AA MLK 524-721 27 2.9e-40 137.42 In-house 2-234 (291) Show / Hide 
Range on Protein: 524-721
Range on HMM: 2-234/291
Sequence Identity: 27% (65 aa)

NFCDKLGSGGFGTVYKGRLLNGT----LVAVKELEM---AMQA----DKQFQTEVETLGKIHHIN----LVRLLGYCYED-NRKLLVYEYMPNGSLEKLL
.|  ..|||.|| |.|||  | .     ||||. .    ...     ...|..|.. | .. | |     ....| | .. .  ..| ||...|||  .|
QFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVL

FLDDAKHF-----------CSWANRFSIALGIARGITYLHDECQECILHCDIKPQNILLDE------SFCPKVADFGLAKLMKRERALSVTTVRGTRGYL
   . | .            . .  ...|| .|||. ||| . .  | | |.|..|||.||          |..|||... ...      .  .||  . 
HGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWM

APEWI---SNLPITTKVDVYSFGMVLLEIISGRE
||| |    . . . |.||.|.|.|| |......
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREV
Kinase IRAKg_n-2.AA S_TKc 523-802 24 4.5e-37 130.41 SMART 1-231 (231) Show / Hide 
Range on Protein: 523-802
Range on HMM: 1-231/231
Sequence Identity: 24% (72 aa)

DNFCDKLGSGGFGTVYKGRLLN-GTLVAVKELEMAMQADKQFQTEVETLGKIHHINLVRLLGYCYEDNRKLLVYEYMPN--GSLEKLLFLDDAKH----F
  . .|.|.|.||.|||.|  . | .||.|..       .... |.. | | || |.|.|...... ..  .| ||...  |.| ...     .     |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

CSWANRFSIALGIARGITYLHDECQECILHCDIKPQNILLDESFCPKVADFGLAKLMKRERALSVTTVRGTRGYLAPEWISNLPITT-KVDVYSFGMVLL
     || ..  |.... |.|   .  |.|.|.||.||||||  . |..|||||...        ||. ||. |.||| .   . .. |.|..|.| .| 
PE-HARF-YMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EIISGREKYIMTISAINSENSRWCLSDWAYNMYQAGDMESIVDKKLVGEEVDFMQFKRLLKVALWCIQHDAHARPSMGKVVQ-----MMEDTV
| ..|.  .                           .|. . .| .          . ..     | | |   ||.  .. |     ..   .
EMLCGYPPFP--------------------------QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKg_n-2.AA Pkinase_Tyr 524-718 32 1.3e-34 117.88 Pfam 2-209 (270) Show / Hide 
Range on Protein: 524-718
Range on HMM: 2-209/270
Sequence Identity: 32% (71 aa)

NFCDKLGSGGFGTVYKGRLL-----NGTLVAVKEL-EMAMQAD---KQFQTEVETLGKI-HHINLVRLLGYCYEDNRK---LLVYEYMPNGSLEKLLFLD
 |  |||.| ||.||||..      ... |||| | | ||. .   . |  |.... .. || |.|||.| |... .    ..| ||||.|.|  | .| 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL--LDYLR

DA---KHFCSWANRFSIALGIARGITYLHDECQECILHCDIKPQNILLDESFCPKVADFGLAKLM-----K-RERALSVTTVRGTRGYLAPEWISNLPIT
.    |.  .     .... ||.|  ||..     . | |.   |.|..|... |..|||||...       | |  .   .. .    ||| |..   |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFT

TKVDVYSFGMVLLEIIS
|| ||.||| .. ||..
TKSDVWSFGVLMWEIFT
Kinase IRAKg_n-2.AA LRRK 513-720 23 2.3e-31 108.18 In-house 1-279 (351) Show / Hide 
Range on Protein: 513-720
Range on HMM: 1-279/351
Sequence Identity: 23% (71 aa)

FTYQQLQTFTDNFCDKLGSGGFG-TVYKGRLLN---------------------------GTLVAVKELEM-----------------------------
. ....          .|.|||| .||.... .                           .. ||.| ...                             
LKIEEQ----------IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDM

------AMQADKQFQTEVETLGKIHHINLVRLLGYCYEDNRKLLVYEYMPNGSLEKLLF---LDDAKHFCS----WANRFSIALGIARGITYLHDECQE-
      .. |   |. ||  . . .| |.| |.|.| .  .  .| ||.|.|.| ..|.    |   ||      |  .  ||| ||.|. |||.  .  
DQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGF-HFMKAHISWMLKLKIALQIAKGMEYLHS--HNP

CILHCDIKPQNILL---D---------ESFCPKVADFGLAKLMKRERALS--VTTVRGTRGYLAPEWIS---NLPITTKVDVYSFGMVLLEIISGR
 |.|.| |. ||||   .         .  | |.||||.   |     ..  . .. |. |..||| .    .   |.|||.|||||.| |.....
PIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase IRAKg_n-2.AA TyrKc 523-798 24 1.4e-29 105.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 523-798
Range on HMM: 1-280/280
Sequence Identity: 24% (75 aa)

DNFCDKLGSGGFGTVYKGRLLNGTLVAVKELEMAMQADKQFQTEVETLGKI--HHINLVRLLGYCYED-------NRKLLVYEYMPNGSLEKLL-FLDDA
  . .|||.| ||.||||..   . |||| |       . |  | . . |.  || |.|||.|.| ..          ..| ||||.|.| . |    . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

KHFCSWANRFSIALGIARGITYLHDECQECILHCDIKPQNILLDESFCPKVADFGLAKLMKRE----RALSVTTVR---GTRG-----YLAPEWISNLPI
    ...   |... ||.|  |||.    .. | |.   |.|..| .. |..||||..  . .     . .. ...   |...      .||| |     
---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TTKVDVYSFGMVLLEIIS-GREKYI------MTISAINSENSRWCLSDWAYNMYQAGDMESIVDKKLVGEEVDFM----QFKRLLKVALWCIQHDAHARP
||| ||.||| .. || . | . |       |. . .             ..  ..|..  . .  .       |      . . .. ..| ..|.. ||
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV-------------IEYVKQGYRMPQPPNDY-----P-MSFVCCPDEMYQIMKQCWHEDPEDRP

SMGKVVQMM
..  ... .
TFSEIHECF
Kinase IRAKg_n-2.AA ULK 643-720 31 4.5e-20 66.84 In-house 151-253 (329) Show / Hide 
Range on Protein: 643-720
Range on HMM: 151-253/329
Sequence Identity: 31% (32 aa)

ILHCDIKPQNILLDESF------------CPKVADFGLAKLMK---RERALSVTTV-----RGTRGYLAPEWISNL----PIT-TKVDVYSFGMVLLEII
| |.||||||||... .            . |.||||.|| .     | .. .|.|     .||  | ||. ....    | .  |.|..|.|... |..
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

SGR
 |.
YGK
Kinase IRAKg_n-2.AA STE 624-720 29 7.6e-20 66.84 In-house 156-265 (359) Show / Hide 
Range on Protein: 624-720
Range on HMM: 156-265/359
Sequence Identity: 29% (35 aa)

IALGIARG-ITYLHDECQECILHCDIKPQNILLDESFCPKVADFGLAKLMKRERA--------------LSVT-TVRGTRGYLAPEWISN------LPIT
|.  | .|   |||.     | | ||||.||||      | .|||... .  . |               . . |. ||  . ||| |..       . .
ICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD

TKVDVYSFGMVLLEIISGR
||.|..|.| ...| . |.
TKCDIWSLGCTIIEMATGK
Kinase IRAKg_n-2.AA ULK 643-720 31 1.8e-19 65.84 In-house 147-249 (324) Show / Hide 
Range on Protein: 643-720
Range on HMM: 147-249/324
Sequence Identity: 31% (32 aa)

ILHCDIKPQNILLDESF------------CPKVADFGLAKLMK---RERALSVTTV-----RGTRGYLAPEWISNL----PIT-TKVDVYSFGMVLLEII
| |.||||||||. . .            . |.||||.||       |  .  |.|     .||  | ||. ....    | .  |.|..|.|... |..
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

SGR
 |.
YGK
Kinase IRAKg_n-2.AA STE 523-607 19 4e-17 57.1 In-house 1-128 (359) Show / Hide 
Range on Protein: 523-607
Range on HMM: 1-128/359
Sequence Identity: 19% (25 aa)

DNFCDKLGSGGFGTVYKGRLLN----------------GTLVAVKELEMAM------------------QADKQFQTEVETLGKIH--HINLVRLLGYCY
  . .|.|.|.||||||..  .                |...|.|....                    .  .|.. |.... | .  | | |. .|...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------NRKLLVYEYMPNGSLEKLL
 .       .   .. |||..|||....
KEGHNHKNDDELWICMEYMDGGSLDDII
Kinase IRAKg_n-2.AA ULK 527-607 25 3.4e-16 54.02 In-house 5-108 (324) Show / Hide 
Range on Protein: 527-607
Range on HMM: 5-108/324
Sequence Identity: 25% (26 aa)

DKLGSGGFG-TVYKGR-LLN---GTLVAVKELE---MAMQADK--------QFQTEVETLGKIH---HIN--LVRLLGYCYED--NRKLLVYEYMPNGSL
..||.| || .|||||   .   . .||.|  .   | ..  .        ... |.... |..   | |   |.|. .....  |   ...|| . | |
HCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDL

EKLL
|...
EQYI
Kinase IRAKg_n-2.AA ULK 527-607 24 1e-14 47.84 In-house 5-111 (329) Show / Hide 
Range on Protein: 527-607
Range on HMM: 5-111/329
Sequence Identity: 24% (26 aa)

DKLGSGGFGTVYKGR-LLN----GTLVAVKELE---MAMQADK--------QFQTEVETLGKIH----HIN----LVRLLGYCYED--NRKLLVYEYMPN
..||.| ||.|||||   .    . .||.| ..   | .. .         ... |.... |..    |.|     |.|. .....  |   ...|| . 
HCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNG

GSLEKLL
| ||...
GDLEQYI
Kinase IRAKg_n-2.AA LRRK 779-800 31 0.00339 7.14 In-house 330-351 (351) Show / Hide 
Range on Protein: 779-800
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

WCIQHDAHARPSMGKVVQMMED
.| |||   ||.. ..|. ...
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKg_n-2.AA LISK 773-798 30 0.135375 0.72 In-house 271-296 (296) Show / Hide 
Range on Protein: 773-798
Range on HMM: 271-296/296
Sequence Identity: 30% (8 aa)

LLKVALWCIQHDAHARPSMGKVVQMM
.|.....|.  |   |||  ..||  
FLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase IRAKg_n-2.AA MLK 780-798 42 0.145722 1.35 In-house 273-291 (291) Show / Hide 
Range on Protein: 780-798
Range on HMM: 273-291/291
Sequence Identity: 42% (8 aa)

CIQHDAHARPSMGKVVQMM
| . |.| |||.  .||  
CWNQDPHKRPSFRQIVQHL
Kinase IRAKg_n-2.AA IRAK 771-798 32 0.156505 1.4 In-house 290-317 (317) Show / Hide 
Range on Protein: 771-798
Range on HMM: 290-317/317
Sequence Identity: 32% (9 aa)

KRLLKVALWCIQHDAHARPSMGKVVQMM
| .. .|. |  | |  |..| .|.| .
KEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAKg_n-2.AA Dicty4 779-800 37 0.265323 0.3 In-house 254-277 (277) Show / Hide 
Range on Protein: 779-800
Range on HMM: 254-277/277
Sequence Identity: 37% (9 aa)

WCIQHDAHARPSMGKVVQM--MED
||  ||   |||.  ..|   .| 
WCWDHDPQHRPSFEEIIQRRILEH
Kinase IRAKg_n-2.AA Pkinase_Tyr 778-798 19 4.820708 0.77 Pfam 250-270 (270) Show / Hide 
Range on Protein: 778-798
Range on HMM: 250-270/270
Sequence Identity: 19% (4 aa)

LWCIQHDAHARPSMGKVVQMM
. | ..|.  ||..  .....
KQCWHYDPEDRPTFSEIHEQL