Gene IRAKh_c-2 (S.moellendorffii)

IRAKh_c-2

Species: S.moellendorffii
Alias: IRAKh_c-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKh

Sequence

Name Sequence Type Origin Length Description Download
IRAKh_c-2.AA Protein None 302 None Fasta, JSON
IRAKh_c-2.NA RNA None 909 None Fasta, JSON
IRAKh_c-2.kin_dom Protein Kinase Domain None 290 None Fasta, JSON

Protein domain

Protein domains of IRAKh_c-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAKh_c-2.AA TKL 14-288 20 2e-65 223.69 In-house 1-364 (364) Show / Hide 
Range on Protein: 14-288
Range on HMM: 1-364/364
Sequence Identity: 20% (79 aa)

VGEGSFGQVFRGILTN---------GKVVAIKRMDTFAGQC-----------------------AEAEKEFRIEVD-LLSRMNHPHLVRLFGYCADGSQ-
.|.|.||.|..|.. .         ||.||.|.. .   ..                       |. ...|..|.  ..|| .||..|.. ||| .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLIVYEFMSNGSLESYFAGRCLYRSGFKLDFRRRLLISLGCAKGLAFLHA-----GGEDGDPIVHRDFKSSNILLDSYFS--------
              ||.|....|||..|.             . .|. ..|..|.|...||.     ..    ||.||| ||.|||.|. .         
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCT--KPPIIHRDLKSKNILVDENWTNVSNYMYN

------AKISDFGFAKLL-------------------QRNQSHASTRVIGTFGYFDPHYTA----------------TGRLTVKADVYSFGVVLLQLLTG
      .||.|||... .                   | |.. .. ...||...  |                     .  . |.||||||.||  .||.
PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTR

KPAVVSFGGDDVPQNIVSWAEPCLNDKRKLRR--ILDKDLGSTYP--------PKCAHKLALLASCCLRENAEARPSMAQCVQTI
..       .| | . . .. | . .  ...    |   . .. .        | | . .. |. .|  ...|.|||. ......
CR-----PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKh_c-2.AA IRAK 8-219 36 5.4e-53 182.37 In-house 1-226 (317) Show / Hide 
Range on Protein: 8-219
Range on HMM: 1-226/317
Sequence Identity: 36% (83 aa)

FNMRNLVGEGSFGQVFRGILTNGK-VVAIKRMDTFAG-QCAEAEKEFRI---EVDLLSRMNHPHLVRLFGYCADGSQRLIVYEFMSNGSLESYFAGRCLY
|.  |. ||| || |.|| . |   ..|.|.    |  .. | ...|.    |. ...|  ||..| | |||.....   ||..|.|||||     .|. 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRL--WCQD

RSGFK--LDFRRRLLISLGCAKGLAFLHAGGED-GDPIVHRDFKSSNILLDSYFSAKISDFGFAKLL---QRNQSHAS-----TRVIGTFGYFDPHYTA-
 ..    |   .|. |..| |.|. |||    . . || |.| ||.|||||  | .||.||| .      . . .. .      .|.||  |  |..   
GQCPPKPLSWHQRCSICWGTACGIQFLH--QNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRD

-TGRLTVKADVYSFGVVLLQLLTGKPAVVS
 .|.||.| ||||||.||| .||| .||..
PQGQLTKKTDVYSFGIVLLEVLTGCRAVYD
Kinase IRAKh_c-2.AA TKL-Unique 10-214 30 4.4e-41 142.65 In-house 1-225 (290) Show / Hide 
Range on Protein: 10-214
Range on HMM: 1-225/290
Sequence Identity: 30% (69 aa)

MRNLVGEGSFGQVFRGILTNGKVVAIKRMDTFAGQCAEAEKEFRIEVDLLSRMN-HPHLVRLFGYCA----DGSQRLIVYEFMSNGSLESYFA-GRCLY-
  |..|||..|||..|.  .|. ||||.    ...  | ..||. || .... . || .|...|||.    . ... || |... ||| .. .    .  
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--RSGFKLDFRRRLLISLGCAKGLAFLHAGGEDGDPIVHRDFKSSNILLDSY-----FSAKISDFGFAKLLQ-RNQSHAS-------TRVIGTFGYFDPH
  ..  ||.. .|. . . .|.|. .||  .    || ||| ||||.|.|.      ...||.|||..|..  .|.. ..       . ..|.| .  | 
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEP---PIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

YTAT--GRLTVKADVYSFGVVLLQLLTGK
 .       . |.||||||.||  ..|.|
VLRMNFCQYSEKSDVYSFGIVLWEIATRK
Kinase IRAKh_c-2.AA S_TKc 8-293 21 3.3e-37 130.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-293
Range on HMM: 1-231/231
Sequence Identity: 21% (64 aa)

FNMRNLVGEGSFGQVFRGILTN-GKVVAIKRMDTFAGQCAEAEKEFRIEVDLLSRMNHPHLVRLFGYCADGSQRLIVYEFMSN--GSLESYFAGRCLYRS
. . ...|.|.||.|.... .. |..||||...          . .| |...|.. .||..|.|.... | .   .| |....  |.| .|   |   . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

GFKLDFRRRLLISLGCAKGLAFLHAGGEDGDPIVHRDFKSSNILLDSYFSAKISDFGFAKLLQRNQSHASTRVIGTFGY-----FDPHYTATGRLTV-KA
.|...  .   .    ...|...|  |     |.||| | .|||||.    ||.|||.|..|        | ..||  |     .          .  |.
RFPFPE-HARFYMYQICCALEYCHSHG-----IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--------GYGKCKC

DVYSFGVVLLQLLTGKPAVVSFGGDDVPQNIVSWAEPCLNDKRKLRRILDKDLGSTYPPKCAHKLALLASCCLRENAEARPSMAQCVQ----TIEEILV
|..|.|..|  .|.|.|                      .... ...|.             . .  . . ||. . | ||.  .. |          .
DWWSCGCILYEMLCGYPPFP-------------------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKh_c-2.AA MLK 8-214 26 8.2e-36 121.76 In-house 1-233 (291) Show / Hide 
Range on Protein: 8-214
Range on HMM: 1-233/291
Sequence Identity: 26% (63 aa)

FNMRNLVGEGSFGQVFRGILTNGK----VVAIKRMDTFAGQCAEAE----KEFRIEVDLLSRMNHPH----LVRLFGYCAD-GSQRLIVYEFMSNGSLES
..    .|.||||.|..|   |      .||.|| .. .  ..  .    ..|. |. .|....||      ... | |.. ... .|| |....||| .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

YFAG-RCLYR-------SGFKLDFRRRLLISLGCAKGLAFLHAGGEDGDPIVHRDFKSSNILLDS------YFSAKISDFGFAKLLQRNQSHASTRVIGT
. .| |           . .  |.   . ..| ||.|...||.  .. .||.||| ||.|||.|       .  .||.||| .. .....    .  .||
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHS--MAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGT

FGYFDPHYT---ATGRLTVKADVYSFGVVLLQLLTGK
. .  |  .     .. . |.||.|.|||| ..||..
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase IRAKh_c-2.AA Dicty4 8-214 29 9.6e-36 116.81 In-house 1-214 (277) Show / Hide 
Range on Protein: 8-214
Range on HMM: 1-214/277
Sequence Identity: 29% (67 aa)

FNMRNLVGEGSFGQVFRGILTNGKVVAIKRMDTFAGQCAEAE-KEFRIEVDLLSRMNHPHLVRLFGYCA----DGSQRLIVYEFMSNGSLESYFAGRCLY
 |  .. |.||||.|..|.   || ||.| .        |.. .||| ||....   ||... . |.|       .  .|| |.|. |.|.|      | 
INIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYS------LL

RS-------GFKLDFRRRLL---ISLGCAKGLAFLHAGGEDGDPIVHRDFKSSNILLDSYFSAKISDFGFAKLLQRNQSHAS--TRVIGTFGYFDPHYTA
..         |||. ...    . . .|.|.. ||.   .   |.||| ||.|.| |  . .|..|||.... ..  .|    . ..|| ..  |   .
HDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV---IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMM

TGRLTVKADVYSFGVVLLQLLTGK
  . . |||||||| || ..||..
HQPYNEKADVYSFGIVLWEILTRQ
Kinase IRAKh_c-2.AA STE 8-215 19 1.5e-34 119.5 In-house 1-266 (359) Show / Hide 
Range on Protein: 8-215
Range on HMM: 1-266/359
Sequence Identity: 19% (56 aa)

FNMRNLVGEGSFGQVFRGILTN----------------GKVVAIKRMD----------TFAGQCA------EAEKEFRIEVDLLSRMN--HPHLVRLFGY
.     .|.|.||.|....  .                |...|||.|.          . . |        | ....  |.......|  ||. |. .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC

CADG-------SQRLIVYEFMSNGSLESYFAGRCLYRSGFK--------LDFRRRLLISLGCAKG-LAFLHAGGEDGDPIVHRDFKSSNILLDSYFSAKI
. ..       ..  |. |.|..|||..    ..    ...        ..      |   . || |..||  .     |.||| |..||||     .|.
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-----IIHRDIKPANILL-----VKL

SDFGFAKLLQRN-------------QSHASTR--VIGTFGYFDPHYTATGRLTV-----------KADVYSFGVVLLQLLTGKP
.|||... |. .             .. .. |  ..||       . |  ...            |.|..|.| ... ..||||
CDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKP
Kinase IRAKh_c-2.AA TK 8-212 15 9.2e-32 103.17 In-house 1-389 (486) Show / Hide 
Range on Protein: 8-212
Range on HMM: 1-389/486
Sequence Identity: 15% (60 aa)

FNMRNLVGEGSFG---QVFRGILTNGK--------------------------VVAIKRMDTFAGQCAEAEKE--------------FRIEVDLLS--RM
  . .  ||| ||   .|..|.. ...                           ||.| .   ... .|....              .  |  ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHPHLVRLFGYCADG------------SQRLIVYEFMSNGS----LESYFAGRCLYRSG-----------------------------------------
.||..|||.|.| .|               .|| |.|..|.    | .|   .  ...                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------------------------FKLDFRRRLLISLGCAKGLAFLHAGG-EDGDPI---VHRDFKSSNILLDSYFS-----------AKISDFG
                              .|. ...| ...  |.|...||. . | .  |   ||||    |.|...              .||.|||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-F--IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFG

FAK-----LLQRNQSHASTRVIGTFG----------------------------------YFDPHYTAT---GRLTVKADVYSFGVVLLQLLT
 ..     |  . .|.   .. .. |                                   .| ...     |. | | ||.||||..  ..|
LSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAKh_c-2.AA DRK 8-212 30 1.4e-29 97.34 In-house 1-197 (258) Show / Hide 
Range on Protein: 8-212
Range on HMM: 1-197/258
Sequence Identity: 30% (64 aa)

FNMRNLVGEGSFGQVFRGILTNGKVVAIKRMDTFAGQCAEAEKEFRIEVDLLSRMNHPHLVRLFGYCADGSQRLIVYEFMSNGSLESYFAGRCLYRSGFK
    | .| |..|.||||    |  ||.|..        .  .||. |..|...  ||  .   | |   .  .|. |.|. |||      . |     .
IKIGNRIGRGNYGEVFRGTW-RGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLY-----NILHDESIE

LDFRRRLLISLGCAKGLAFLHAGGEDGDPIV-HRDFKSSNILLDSYFSAKISDFGFAKLLQRNQSHASTR-VIGTFGYFDPHYTATGRLTVKADVYSFGV
.|  ... . . ||||. .||      .||. ||| || | | |  .  |..||| .   .. ..|  ..  .|| .   |   .  | | |||||||..
MDWPLMKQMMFDCAKGMIYLHC----CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAI

VLLQLLT
||  ..|
VLWECVT
Kinase IRAKh_c-2.AA Pkinase 8-177 25 2.3e-29 104.94 Pfam 1-172 (293) Show / Hide 
Range on Protein: 8-177
Range on HMM: 1-172/293
Sequence Identity: 25% (47 aa)

FNMRNLVGEGSFGQVFRGILTNG-KVVAIKRMDTFAGQCAEAEKEFR-IEVDLLSRMNHPHLVRLFGYCADGSQRLIVYEFMSNG----SLESYFAGRCL
.     .|.||||.|....  .  |.||.|...     . . .  .|  |. .. |.|||. |||.... |..   .| |.. .|    .| .|  .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

YRSGFKL--DFRRRLLISLGCAKGLAFLHAGGEDGDPIVHRDFKSSNILLDSYFSA----KISDFGFAKLL-QRNQSHASTRV
 ... ..  . .    . .  ..||...|.       |.||| |..|||.|.        ||.|||.||..   |.| ..|..
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM-----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC
Kinase IRAKh_c-2.AA LRRK 8-216 24 1.6e-28 97.98 In-house 1-282 (351) Show / Hide 
Range on Protein: 8-216
Range on HMM: 1-282/351
Sequence Identity: 24% (72 aa)

FNMRNLVGEGSFG-QVFRGILTN---------------------------GKVVAIKRMDTF-------------------------------AGQCAEA
.   ...|.|.||  |.|... .                           .. |||| ...                                .  |..|
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EKEFRIEVDLLSRMNHPHLVRLFGYCADGSQRLIVYEFMSNGSLESYFAGRCLYRSGF-----KLDFRRRLLISLGCAKGLAFLHAGGEDGD-PIVHRDF
  ||| || ..|..|||..| |.|.| .   . .| |....|.| ..   .   ..||     ...   .| |.|  |||...||    . . ||.||| 
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFL--HNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH----SHNPPIIHRDL

KSSNILLDSY------------FSAKISDFGFAKLLQRNQSHASTRVIGTFGYFDPHYTATG---RLTVKADVYSFGVVLLQLLTGK-PA
|| |||| |               |||.|||   . |  .. .  .. |..|.  |     .     | |.|.||||..|  |||.. ..
KSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase IRAKh_c-2.AA TK-Unique 8-176 23 3.3e-26 87.45 In-house 1-193 (294) Show / Hide 
Range on Protein: 8-176
Range on HMM: 1-193/294
Sequence Identity: 23% (47 aa)

FNMRNLVGEGSFGQVFRGILTN-------GKVVAIKRMDTFAGQCAEAEKEFRIEVDLLSRMN-HPHLVRLFGYCADGS-QRLIVYEFMSNGSLESYFA-
... ...|||.||||.|| ...        |.||.|     | .  . ...|  |  ...    ||..|...|.| . . . .|..|....|.|..|.  
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATD--TDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRT

GRCLYRSG---------------FKLD---FRRRLL-ISLGCAKGLAFLHA--GGEDGDPIVHRDFKSSNILLDSYFSAKISDFGFAKLLQRNQSHASTR
 |.  |..               ....     ..|. .  ..|.|...|.    .     |||||  ..|.|| ... .||.|||.|. .. |. .....
CRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK-----IVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMC
Kinase IRAKh_c-2.AA Pkinase_Tyr 8-166 25 3.4e-25 85.97 Pfam 1-161 (270) Show / Hide 
Range on Protein: 8-166
Range on HMM: 1-161/270
Sequence Identity: 25% (44 aa)

FNMRNLVGEGSFGQVFRGILT-----NGKVVAIKRMDTFAGQCAEAE---KEFRIEVDLLSRM-NHPHLVRLFGYCA-DGSQ--RLIVYEFMSNGSLESY
  .    |||.||.|..|...     ..  ||.| .     .. . .   ..|  |. ... . .||..||| | |  .| .   .|| |.| .|.| .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

FAGRCLYRSGFKLDFRRRLLISLGCAKGLAFLHAGGEDGDPIVHRDFKSSNILLDSYFSAKISDFGFAKLL
   ..   .. .|.  . | ...  |||...|.. .     ..|||    |.|... . .||.||| |...
LRKHR--EDKQPLTMKDLLQMCWQIAKGMEYLESKN-----CIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase IRAKh_c-2.AA TyrKc 8-288 20 4.2e-24 87.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-288
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

FNMRNLVGEGSFGQVFRGILTNGKVVAIKRMDTFAGQCAEAEKEFRIEVDLLSRM--NHPHLVRLFGYCADG-------SQRLIVYEFMSNGSLESYF-A
  .    ||| ||.|..|...    ||.| .   |      ...|. |  ....   .||..|||.|.| ..        . .|| |.|..|.| .|  .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

GRCLYRSGFKLDFRRRLLISLGCAKGLAFLHAGGEDGDPIVHRDFKSSNILLDSYFSAKISDFGFAKLLQRN-------QSHA-----STR---------
 |        |  .  | ...  |.| ..||       ...|||    |.|... . .|||||| .. .          .        ...         
HRPK------LCMKDLLSFCWQIACGMEYLHSK-----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

--VIGTFGYFDPHYTATGRLTVKADVYSFGVVLLQLLTGKPAVVSFGGD----DVPQNIVSWAEPCLNDKRKLRRILDKDLGSTYPPK----CAHKLALL
  .|            .|. | | ||.||||..  ..|         |.      .| .. . .     ... ... . |.    |      |  ..  .
PECI-----------NYGKFTTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVK-----QGYRMPQPPNDY----P-MSFVCCPDEMYQI

ASCCLRENAEARPSMAQCVQTI
 ..| .|..| ||....... .
MKQCWHEDPEDRPTFSEIHECF
Kinase IRAKh_c-2.AA Pkinase 195-288 16 1.5e-09 34.89 Pfam 190-293 (293) Show / Hide 
Range on Protein: 195-288
Range on HMM: 190-293/293
Sequence Identity: 16% (19 aa)

TVKADVYSFGVVLLQLLTGKPAVVSFGGDDVPQNIVSWAEPCLNDKRKLRRILDKDLGSTYPPKCA-------------------HKLALLASCCLRENA
. |.|..|.|..| ..|.|.            .. . | .. .... ...||....| . .| .|                      .  . ..||. . 
GPKVDMWSCGCILYEMLCGR---------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

EARPSMAQCVQT--I
. ||. .|..|   .
KKRPTAEQILQHPWF
Kinase IRAKh_c-2.AA MLK 256-288 30 1e-06 19.43 In-house 259-291 (291) Show / Hide 
Range on Protein: 256-288
Range on HMM: 259-291/291
Sequence Identity: 30% (10 aa)

PPKCAHKLALLASCCLRENAEARPSMAQCVQTI
|. | . .. | ..|  .... |||..|.||  
PSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase IRAKh_c-2.AA TK 256-288 19 3e-06 15.98 In-house 440-486 (486) Show / Hide 
Range on Protein: 256-288
Range on HMM: 440-486/486
Sequence Identity: 19% (9 aa)

PPKCA--------------HKLALLASCCLRENAEARPSMAQCVQTI
|| |                 ...|  .| ....| ||...|... .
PPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAKh_c-2.AA DRK 256-290 34 2.7e-05 13.91 In-house 224-258 (258) Show / Hide 
Range on Protein: 256-290
Range on HMM: 224-258/258
Sequence Identity: 34% (12 aa)

PPKCAHKLALLASCCLRENAEARPSMAQCVQTIEE
|. |  | . |   |. |.   |||| .|.. .| 
PQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase IRAKh_c-2.AA TK-Unique 256-288 29 3.9e-05 13.81 In-house 261-294 (294) Show / Hide 
Range on Protein: 256-288
Range on HMM: 261-294/294
Sequence Identity: 29% (10 aa)

PPKC-AHKLALLASCCLRENAEARPSMAQCVQTI
|..|  | .  | ..|.....| ||| .|... .
PEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase IRAKh_c-2.AA IRAK 256-288 30 0.0001 12.86 In-house 285-317 (317) Show / Hide 
Range on Protein: 256-288
Range on HMM: 285-317/317
Sequence Identity: 30% (10 aa)

PPKCAHKLALLASCCLRENAEARPSMAQCVQTI
||. . ... .|.||. . |  |..||. .|..
PPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAKh_c-2.AA Dicty4 256-290 24 0.000119 11.63 In-house 241-277 (277) Show / Hide 
Range on Protein: 256-290
Range on HMM: 241-277/277
Sequence Identity: 24% (9 aa)

PPKCAHKLALLASCCLRENAEARPSMAQCVQT--IEE
|. |  ... |   |. .. . |||.....|    |.
PDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase IRAKh_c-2.AA Pkinase_Tyr 256-288 21 0.00057 14.07 Pfam 238-270 (270) Show / Hide 
Range on Protein: 256-288
Range on HMM: 238-270/270
Sequence Identity: 21% (7 aa)

PPKCAHKLALLASCCLRENAEARPSMAQCVQTI
|..|  ..  |   | ....| ||....... .
PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase IRAKh_c-2.AA LRRK 270-290 23 0.014549 4.87 In-house 331-351 (351) Show / Hide 
Range on Protein: 270-290
Range on HMM: 331-351/351
Sequence Identity: 23% (5 aa)

CLRENAEARPSMAQCVQTIEE
|  .. . ||.. | |.....
CWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKh_c-2.AA Pkinase_Tyr 190-207 50 0.018034 8.99 Pfam 187-204 (270) Show / Hide 
Range on Protein: 190-207
Range on HMM: 187-204/270
Sequence Identity: 50% (9 aa)

ATGRLTVKADVYSFGVVL
..|. |.| ||.||||..
NYGKFTTKSDVWSFGVLM
Kinase IRAKh_c-2.AA TK-Unique 195-207 61 0.05483 2.79 In-house 217-229 (294) Show / Hide 
Range on Protein: 195-207
Range on HMM: 217-229/294
Sequence Identity: 61% (8 aa)

TVKADVYSFGVVL
| | ||.||||..
TTKSDVWSFGVLM