IRAKk_b-1

Species: S.moellendorffii
Alias: IRAKk_b-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKk

Sequence

Name Sequence Type Origin Length Description Download
IRAKk_b-1.AA Protein None 345 None Fasta, JSON
IRAKk_b-1.NA RNA None 1038 None Fasta, JSON
IRAKk_b-1.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of IRAKk_b-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAKk_b-1.AA TKL 36-301 21 1.5e-62 214.13 In-house 1-364 (364) Show / Hide
Range on Protein: 36-301
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

IGHGGFGLVYRGVLPD---------GRLAAVKLMDRQGKQGE---------------------------REFRVEVDMLTRLHSPYLLDLIGYCADKDY-
|| |||| ||.|..           |.  ||| . ..  . .                            ....|. |. ||. | .. ..||| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYSYMANGSLQEHLHSKGKSTLDWGTRILVAFDAAKGLEYLHEYVI-----PPIIHRDFKSSNILLDEHND--------------
              .|. |. .||| ..||        |  |.  | |.|.|..|||         ||||||| ||.|||.||..               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VVLADFGLAKTGA---DKIAGQPSTR--------------VLGTQGYLAPEYAM----------------TGHLTTKSDVYSYGIVLLELITGRLPVDAK
. ..||||...     .. ... ...              . || ...|||  .                 .  ..|.||||.|||| |..|...     
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----

RPPGQNVLVNWALPRLTDREKLAQMVDPYLRS------------QYNMKELVQVAAIAAMCVQPEPDYRPLITDVVQSL
 |  ..    . . ..   | ... .|  ||             . .   . ... .. .| ...|. ||  ..... |
-PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase IRAKk_b-1.AA IRAK 30-237 37 3.9e-59 202.76 In-house 1-230 (317) Show / Hide
Range on Protein: 30-237
Range on HMM: 1-230/317
Sequence Identity: 37% (87 aa)

FSPLNKIGHGGFGLVYRGVLPDGR-LAAVK-LM---DRQGKQGEREFRV---EVDMLTRLHSPYLLDLIGYCADKDYRLLVYSYMANGSLQEHLHSKG-K
|.. |.|| |||| ||||..       ||| |.   | . .. ...|.    |.  ..|.. | ...| |||.. .   ||| ||.||||.  |.  .  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

ST---LDWGTRILVAFDAAKGLEYLHEYV-IPPIIHRDFKSSNILLDEHNDVVLADFGLAKTG--ADKIAGQPS-----TRVLGTQGYLAPEYAM--TGH
 .   | | .|. ..  .|.|...||.     ||||.| ||.|||||.|    ..||||.  |  |     |..      .| ||  |..||.    .| 
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTTKSDVYSYGIVLLELITGRLPVDAKRPP
||.|.|||| ||||||..||. .|.  ||.
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPE

Kinase IRAKk_b-1.AA TKL-Unique 32-230 30 6.2e-47 162.25 In-house 1-233 (290) Show / Hide
Range on Protein: 32-230
Range on HMM: 1-233/290
Sequence Identity: 30% (71 aa)

PLNKIGHGGFGLVYRGVLPDGRLAAVKLM--DRQGKQGEREFRVEVDMLTRLH-SPYLLDLIGYCA----DKDYRLLVYSYMANGSLQEHLHS-------
..|||| ||.| ||.|. .    | ...     . .. ..||. ||  . .|| .| .. ..|||.    .  .. .| .|.  ||| ..||        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-KGKSTLDWGTRILVAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDEH-----NDVVLADFGLAKTGADKIAGQPS-------TRVLGTQGYLAPEYAM
 . ...|..  |.  | |.|.|..||| .  | ||||| ||||.|.|..     . . ..||||.|. .  ...  .       . ..|.  ..|||  .
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

T--GHLTTKSDVYSYGIVLLELITGRL------P
    . ..||||||.|||| |..|. .      |
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP

Kinase IRAKk_b-1.AA Pkinase 30-244 26 7.1e-44 156.22 Pfam 1-228 (293) Show / Hide
Range on Protein: 30-244
Range on HMM: 1-228/293
Sequence Identity: 26% (63 aa)

FSPLNKIGHGGFGLVYRGVLPDGRL-AAVKLMDRQGKQG--EREFRV--EVDMLTRLHSPYLLDLIGYCADKDYRLLVYSYMANG----SLQEHLH--SK
.  . ||| |.|| ||...  . .   ||| ......    ... |   |. .. ||..|. . |.... |||.  .|  |. .|    .| ....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKSTLDWGTRILVAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDEHNDV----VLADFGLAKTGADKIAGQPSTRVLGTQGYLAPEYAM-TGHLTTKSD
|. .... . . ..   ..||||.|.     ||||| |..|||.|.....     ..||||||       ..  | . || .|.|||  .   . ..|.|
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSYGIVLLELITGRLPVDAK----RPPGQNVLVN
..|.|..| |...||.| . .    .   |.....
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMIC

Kinase IRAKk_b-1.AA S_TKc 30-305 23 4.4e-41 143.71 SMART 1-231 (231) Show / Hide
Range on Protein: 30-305
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

FSPLNKIGHGGFGLVYRGVLPD-GRLAAVKLMDRQGKQGEREFRVEVDMLTRLHSPYLLDLIGYCADKDYRLLVYSYMAN--GSLQEHLHSKGK----ST
.  |.|||.|.|| ||...  . ||. |.| ..       . .| |...| . | |..  |.... | |.  .|  |. .  |.| ......|.    . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWGTRILVAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDEHNDVVLADFGLAKTGADKIAGQPSTRVLGTQGYLAPEYAMTGHLTT-KSDVYSYGIVL
..  .   ..   ...|||.|.     ||||| | .||||||   . ..|||||.           | . ||  |.|||     . .. |.|..| |..|
FPE-HARFYMYQICCALEYCHSH---GIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LELITGRLPVDAKRPPGQNVLVNWALPRLTDREKLAQMVDPYLRSQYNMKELVQVAAIAAMCVQPEPDYRPLITDVVQ-----SLIPLV
 |...|. | .      .... .  .                           ..  .   | | .|. || . .. |      . | .
YEMLCGYPPFP-----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IRAKk_b-1.AA TK 30-301 15 5.8e-38 124.32 In-house 1-486 (486) Show / Hide
Range on Protein: 30-301
Range on HMM: 1-486/486
Sequence Identity: 15% (78 aa)

FSPLNKIGHGGFG---LVYRGVLPDGR--------------------------LAAVKLMDRQGKQGERE-----------------FRVEVDMLT--RL
   ..|.|.| ||    ||.| . ...                            ||| .     . ..|                 .  |  |.    .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HSPYLLDLIGYCADK------------DYRLLVYSYMANGS----LQEHLHSKG----------------------------------------------
| | .. |.|.| ..               ..|  ||..|.    |...|...                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------KSTLDWGTRILVAFDAAKGLEYLHEY---VIPPIIHRDFKSSNILLDEHND-----------VVLADFGLAK
                            |..|.  ...  ....|.|.||||.     |. ..|||    |.|..|.|            . .|||||..
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

TGA----DKIAGQPSTRVLGTQG----------------------------YLAPEYAM---------TGHLTTKSDVYSYGIVLLELIT-GRLPVDAKR
.|      .|      .. ...|                            ..|||  .         .|. ||||||.|.|... |. | |. |     
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP-----

PPG-QNVLVNWA-------LPRLTDREKL-----------AQMVDPYLRSQ---YNMKELV-----QVAAI-AAMCVQPEPDYRPLITDVVQSL
..|  .    |.       . .|..  .|            .|  | . .    |.|         .. ..   .| ...|. ||  ..... |
YYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase IRAKk_b-1.AA STE 30-230 22 5.3e-37 128.23 In-house 1-267 (359) Show / Hide
Range on Protein: 30-230
Range on HMM: 1-267/359
Sequence Identity: 22% (61 aa)

FSPLNKIGHGGFGLVYRGVLPD----------------GRLAAVKLMDRQGKQG-----------------EREFRVEVDMLTRLH--SPYLLDLIGYCA
.  . |||.|.|| ||...  .                |.. |.| |. . ..                  . ..  |.... ...  .|.    .|.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DK-------DYRLLVYSYMANGSLQEHLH---SKGK---------STLDWGTRILVAFDAAKG-LEYLHEYVIPPIIHRDFKSSNILLDEHNDVVLADFG
..       |.  ..  ||..||| . ..   ..||         ....    . ....  || |.|||.     ||||| |..||||     | |.|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LAKTGADKIA--------------GQPSTRVLGTQGYLAPEYAMT------GHLTTKSDVYSYGIVLLELITGRLP
...  .|..|              .| .. . ||. . |||  .       .. .||.|..| |....|..||. |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP

Kinase IRAKk_b-1.AA LRRK 30-232 25 1.5e-36 126.81 In-house 1-284 (351) Show / Hide
Range on Protein: 30-232
Range on HMM: 1-284/351
Sequence Identity: 25% (75 aa)

FSPLNKIGHGGFG-LVYRGVLPD---------------------------GRLAAVKLMDR------------------------QGKQGE---------
.   ..|| |||| .|||. . .                           .  .|.| ..|                        |.             
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

--REFRVEVDMLTRLHSPYLLDLIGYCADKDYRLLVYSYMANGSLQEHLHSKGKST-------LDWGTRILVAFDAAKGLEYLHEYVIPPIIHRDFKSSN
  |||| || .. .|. |....|.|.|   . . .|  |. .|.|...||.| ..        ..|.... .| . |||.||||    ||||||| || |
AFREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPN

ILL---DEH-------NDVV--LADFGLAKTGADKIAGQP-STRVLGTQGYLAPEYAMTG---HLTTKSDVYSYGIVLLELITGR-LPVD
|||   ...       ..|.  .||||.      .. .     ...|. |..|||    .     |.|.|.||.|..| ||.|.. .| |
ILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD

Kinase IRAKk_b-1.AA Dicty4 30-227 34 4e-36 118.09 In-house 1-213 (277) Show / Hide
Range on Protein: 30-227
Range on HMM: 1-213/277
Sequence Identity: 34% (74 aa)

FSPLNKIGHGGFGLVYRGVLPDGRLAAVKLM--DRQG--KQGEREFRVEVDMLTRLHSPYLLDLIGYCA----DKDYRLLVYSYMANGSLQEHLHS----
    ..|| |.|| ||.|    |   |||..  . |.       ||| ||. .  .  | .. . |.|      .   . |  ||  |.| . ||.    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

-KGKSTLDWGTRIL---VAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDEHNDVVLADFGLAK---TGADKIAGQPSTRVLGTQGYLAPEYAMTGHLTT
 . . .|||....     |||||.|. .||.  .| ||||| ||.|.| |... |  .||||..   .. |. ..| .  . || .. |||  |    . 
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMT--ACGTPCWMAPEVMMHQPYNE

KSDVYSYGIVLLELITG
|.||||.|||| |. |.
KADVYSFGIVLWEILTR

Kinase IRAKk_b-1.AA MLK 30-230 26 1.8e-32 110.03 In-house 1-235 (291) Show / Hide
Range on Protein: 30-230
Range on HMM: 1-235/291
Sequence Identity: 26% (64 aa)

FSPLNKIGHGGFGLVYRGVLPDGRL-----AAVKLMDRQG----------KQGEREFRVEVDMLTRLH-SPYLLDLIGYCADKDY-RLLVYSYMANGSLQ
.  . .||.|.|| |..|.   ...      |||  .             .. |.|.| .. .| ..  .|.   . | |..  .  ..|  |...||| 
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECR-HLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

EHLHS-KGKST-----------LDWGTRILVAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDE------HNDVVLADFGLAKTGADK---IAGQPSTRV
. ||. ..|.             | .  .  |.. |.|..|||.   .|||||| ||.|||.||      | ... .|||...   ..     ...    
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNA----

LGTQGYLAPEY---AMTGHLTTKSDVYSYGIVLLELITGRLP
 ||  . |||    .  .  . |.||.|.|.|| |..|...|
-GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP

Kinase IRAKk_b-1.AA DRK 34-226 37 1.8e-30 100.4 In-house 5-197 (258) Show / Hide
Range on Protein: 34-226
Range on HMM: 5-197/258
Sequence Identity: 37% (74 aa)

NKIGHGGFGLVYRGVLPDGRLAAVKLMDRQGKQGE---REFRVEVDMLTRLHSPYLLDLIGYCADKDYRLLVYSYMANGSLQEHLHSKGKSTLDWGTRIL
| || |..| |.||    |   ||| .       |    ||. |.... .|  |     .| |      . .  ||  |||   ||   .  .||. .. 
NRIGRGNYGEVFRGTW-RGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDE-SIEMDWPLMKQ

VAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDEHNDVVLADFGLAKTGADKIAGQPSTR-VLGTQGYLAPEYAMTGHLTTKSDVYSYGIVLLELIT
 .||.|||. |||    | ||||| || | | |||  |  |||||. |   |.  .  ..   || .  |||       | | ||||..||| |..|
MMFDCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLS-TRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT

Kinase IRAKk_b-1.AA Dicty4-Unclassified 33-227 34 9.5e-30 99.03 In-house 4-204 (263) Show / Hide
Range on Protein: 33-227
Range on HMM: 4-204/263
Sequence Identity: 34% (72 aa)

LNKIGHGGFGLVYRGVLPDGRLAAVKLMDRQGKQGER-----EFRVEVDMLTRLHSPYLLDLIGYC-AD---KDYRLLVYSYMANGSLQEHLH----SKG
.  || | |  |..|.   |.  ||| .   .|   |     .|. ||..|  .  | |. . ||| .    |     |   |  | | |  |     . 
DQFIGKGHFSKVHKGNW-KGKDVAVKKFN-ENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

KS-TLDWGTRILVAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDEHNDVVLADFGLAKTGADKIAGQPSTRVLGTQGYLAPEYAMTGHLTTKSDVYSYG
..  ||    | .||| |.|. .||      .|||| ||||||.| |. .  ||||..         .  | . ||    .||  |    . |||||||.
QPIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFN---FNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

IVLLELITG
..| ||.||
MMLYELATG

Kinase IRAKk_b-1.AA TyrKc 30-301 23 5.2e-27 96.96 SMART 1-280 (280) Show / Hide
Range on Protein: 30-301
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

FSPLNKIGHGGFGLVYRGVLPDGRLAAVKLMDRQGKQGEREFRVEVDMLTRL--HSPYLLDLIGYCADK-------DYRLLVYSYMANGSLQEHLHSKGK
 . . |.|.| || ||.|..   .  ||| .       ...|. |  ....|  | | .. |.|.| ..       .  ..|  ||..|.|...|.....
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

STLDWGTRILVAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDEHNDVVLADFGLAKTGADK-IAGQPSTRVLGT----QGY-------LAPEYAMTGHL
  | . . .  ....|.| ||||.    ..||||    |.|..| . |  .||||.. . |.  .|  |. .  .    .|        .|||  ..|  
K-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TTKSDVYSYGIVLLELITGRLPVDAKRPPGQN----VLVNWALPRLTDREKLAQMVDPYLRSQYNM----KELVQVAAIAAMCVQPEPDYRPLITDVVQS
||||||.|.|... |. |     . . |.       .    .. .. ... . |. ..|      |            |  .| . .|. ||  ..... 
TTKSDVWSFGVCMWEIFT-----YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----P-MSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHEC

L
.
F

Kinase IRAKk_b-1.AA Pkinase_Tyr 30-178 29 1e-25 87.75 Pfam 1-160 (270) Show / Hide
Range on Protein: 30-178
Range on HMM: 1-160/270
Sequence Identity: 29% (49 aa)

FSPLNKIGHGGFGLVYRGVLP-----DGRLAAVKLMDRQGKQGE----REFRVEVDMLTRL-HSPYLLDLIGYCA-DKDY--RLLVYSYMANGSLQEHLH
 . . |.|.| || ||.|..      ..   ||| . ..|   |    ..|  |. ... | | | .. |.| |  ...    ..|  ||..|.| ..|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SK--GKSTLDWGTRILVAFDAAKGLEYLHEYVIPPIIHRDFKSSNILLDEHNDVVLADFGLAKT
..  .|  |.  . .  ... |||.|||..     .||||    |.|..| | |  .|||||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARD

Kinase IRAKk_b-1.AA Pkinase_Tyr 198-230 47 2.9e-07 25.21 Pfam 181-214 (270) Show / Hide
Range on Protein: 198-230
Range on HMM: 181-214/270
Sequence Identity: 47% (16 aa)

LAPEYAMTGHLTTKSDVYSYGIVLLELIT-GRLP
.|||  ..|  ||||||.|.|... |..| |. |
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQP