IRAKm_q-2

Species: S.moellendorffii
Alias: IRAKm_q-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKm

Sequence

Name Sequence Type Origin Length Description Download
IRAKm_q-2.AA Protein None 770 None Fasta, JSON
IRAKm_q-2.NA RNA None 2313 None Fasta, JSON
IRAKm_q-2.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of IRAKm_q-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKm_q-2.AA B_lectin 94-135 29 5.6e-08 28.98 Pfam 66-119 (137) Show / Hide
Range on Protein: 94-135
Range on HMM: 66-119/137
Sequence Identity: 29% (16 aa)

AASLVLQNSGNVLIYSY--N--G-SVWQS--FDFPSEFLLPTQILKT------GM
......|.|||  .| .  |  .  .|||  ||.|.  .||.. | .      .|
NCRAQMQDSGNLVLY-DDNNDSNNVLWQSNTFDHPTDTWLPGMKLGWDNNVTIYM

Kinase IRAKm_q-2.AA TKL 474-752 22 7e-62 211.9 In-house 1-364 (364) Show / Hide
Range on Protein: 474-752
Range on HMM: 1-364/364
Sequence Identity: 22% (86 aa)

LGAGGYGSVYKGVLSD---------GRVVAVKKLDYSGTQGA---------------------------KQFVTEIAGIGGISHVNIVKLCGFCIEGAT-
.| ||.| ||||..           |..|||||.     .                             .... ||  .  ..| |||.. |.|...   
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------QWLLVYEFMPNGSLDKWLFEQTSENLWLSWQQRIDIALGMAQGLVYLHE----ECREP--ILHLDIKPQNILLDTEFV-----------
           |  .|.|..|.|||   |           |.||...||..|.|. |||      |. .  |.| |.|..|||.|  .            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AKVADFGMAKLLENRNETQVMTTM-----------------RGTPGYMAPEWLT----------------HFMATKRCDVYSYGKVLLELIGGRRNI
   .|..||| .. ...... . . |.                 .|||..|||| |                 .| ....|||||.| || |.. ..|  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

DLSKAVNSGDNTQPDESWYFPTWVVNQVEKGNFLEVIDERVRASASE----------NYHQAKKMVHLALWCIQDNADARPSMRTIVEVL
             | .   ....... ...  |  |.|.. |    .          . .  . |  |. .| . ....|||. .|.. |
-------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase IRAKm_q-2.AA Pkinase 473-669 28 1.8e-49 175.47 Pfam 6-209 (293) Show / Hide
Range on Protein: 473-669
Range on HMM: 6-209/293
Sequence Identity: 28% (61 aa)

KLGAGGYGSVYKGVLSDGRV-VAVKKLDYSGTQGAKQFVT-----EIAGIGGISHVNIVKLCGFCIEGATQWLLVYEFMPNG----SLDKWLFEQTSENL
|.|.|..|.|||..  . .  ||||..... ..  .. .|     ||.    ..| |||.| ... ..   . .| |....|    .|  ..    ... 
KIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIST--WRHG

WL--SWQQRIDIALGMAQGLVYLHEECREPILHLDIKPQNILLDTEFVA----KVADFGMAKLLENRNETQVMTTMRGTPGYMAPEWLT-HFMATKRCDV
..  |... ..... ...|| |.|..    |.| |.||.|||.| . .     |..||| ||...     . |||  |||.|||||..  . . ....|.
CFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSYGKVLLELIGGR
.|.| .| |.. ||
WSCGCILYEMLCGR

Kinase IRAKm_q-2.AA IRAK 471-673 37 2.3e-46 160.36 In-house 4-225 (317) Show / Hide
Range on Protein: 471-673
Range on HMM: 4-225/317
Sequence Identity: 37% (84 aa)

STKLGAGGYGSVYKGVLSDGR-VVAVKKL----DYSGTQGAKQFVT---EIAGIGGISHVNIVKLCGFCIEGATQWLLVYEFMPNGSLDKWLFEQTSENL
. ..| ||.| ||.|...    ..|||||    | | ..  ..| .   |.     . | ||| | |.|.|.  .  |||..||||||   |  |.  . 
DNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQ-CHCLVYPYMPNGSLEDRLWCQDGQCP

W--LSWQQRIDIALGMAQGLVYLHEEC-REPILHLDIKPQNILLDTEFVAKVADFGMAKLL---ENRNETQV---MT-TMRGTPGYMAPEWLT--HFMAT
   |||.||..|..| | |. .||.     || | |||. |||||  |..| .|||..      ...  . .   || . |||  ||.|| ..      |
PKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLT

KRCDVYSYGKVLLELIGGRRNID
|. |||| | ||||.. |.|  .
KKTDVYSFGIVLLEVLTGCRAVY

Kinase IRAKm_q-2.AA TKL-Unique 470-666 31 2.5e-42 146.95 In-house 1-222 (290) Show / Hide
Range on Protein: 470-666
Range on HMM: 1-222/290
Sequence Identity: 31% (70 aa)

YSTKLGAGGYGSVYKGVLSDGRVVAVKKLDY---SGTQGAKQFVTEIAGIGGIS-HVNIVKLCGFCIE---GATQWLLVYEFMPNGSLDKWLF------E
 . |.|.||||.||||.   |  ||.|..     |  .  . |  |.  .  .  | |||.. |.|.     . .. .| |..| |||.. |        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

QTSENLWLSWQQRIDIALGMAQGLVYLHEECREPILHLDIKPQNILLDTE-----FVAKVADFGMAKLLENRNETQVM-------TTMRGTPGYMAPEWL
  ..|. |..|||...|. .|||. ||| .    |.|.|.|..|.|.| .     . .|..||| .|.. ..|.. .        .|  |.. .|||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

TH--FMATKRCDVYSYGKVLLELI
.   .. .. .||||.| || |..
RMNFCQYSEKSDVYSFGIVLWEIA

Kinase IRAKm_q-2.AA MLK 468-666 25 6.9e-41 139.59 In-house 1-230 (291) Show / Hide
Range on Protein: 468-666
Range on HMM: 1-230/291
Sequence Identity: 25% (60 aa)

KGYSTKLGAGGYGSVYKGVLSDGR----VVAVKKLD---YSGTQG----AKQFVTEIAGIGGISHVN----IVKLCGFCIEGATQWLLVYEFMPNGSLDK
   ....|.|..|.|.||.    .    .||||. .   .   .     ...| .|.     .|| |    |... | |..   . ..| |....|||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLFEQTSENL----------WLSWQQRIDIALGMAQGLVYLHEECREPILHLDIKPQNILLD------TEFVAKVADFGMAKLLENRNETQVMTTMRGTP
 | ...|.              . .. ...|| .|.|. |||.. . || | |.|..|||.|       . ..|..||| .. . .. ..  |. ..||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTN--MMSNAGTY

GYMAPEWL---THFMATKRCDVYSYGKVLLELI
 .|||| .    . . .. |||.|.| || |..
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEML

Kinase IRAKm_q-2.AA LISK 473-670 28 1.3e-35 113.04 In-house 1-237 (296) Show / Hide
Range on Protein: 473-670
Range on HMM: 1-237/296
Sequence Identity: 28% (70 aa)

KLGAGGYGSVYKGVLS-DGRVVAVKKLD-------YSGTQGAKQFVTEIAGIGGISHVNIVKLCGFCIEGATQWLLVYEFMPNGSLDKWLFEQTSENLWL
..| |..|.|||| .  .|.|.|.|..        .  .|  | .  |.. .  ..| |||.  | | .   |  .| |..  | |   |.   .    |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQ--KFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPL

SWQQRIDIALGMAQGLVYLHEECREPILHLDIKPQNILLDTE----FVAKVADFGMAKLLENRNET---------------------------------Q
.|.||..|||. |.|. |||. .   |.| | | .|.|...     . .||.||| |.... .|                                   .
PWPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKR

VMTTMRGTPGYMAPEWLTHFMATKRCDVYSYGKVLLELIGGRR
 ||   |||  |||| |.    . .|||.|.| ||.|.|....
RMTIC-GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVK

Kinase IRAKm_q-2.AA Dicty4-Unclassified 471-668 33 4.1e-35 117.69 In-house 4-204 (263) Show / Hide
Range on Protein: 471-668
Range on HMM: 4-204/263
Sequence Identity: 33% (71 aa)

STKLGAGGYGSVYKGVLSDGRVVAVKKLDYSGTQGAK-----QFVTEIAGIGGISHVNIVKLCGFCIEG---ATQWLLVYEFMPNGSLDKWLFEQTSE-N
   .| |    |.||.   |. |||||.  ..   .       |  |..  | |.| | ||. | ||           | |||. | |      . || .
DQFIGKGHFSKVHKGNW-KGKDVAVKKFN-ENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

LWLSWQQ--RIDIALGMAQGLVYLHEECREPILHLDIKPQNILLDTEFVAKVADFGMAKLLENRNETQVMTTMRGTPGYMAPEWLTHFMATKRCDVYSYG
  ..      | .|.  |||. .||   |. . | |||  |||.|  | .|.||||..   ..   .. |||  |||   .|| | |   . . |||||.
QPIKLDDTLIIKYAFDIAQGMQHLH--TRN-FIHRDIKSSNILMDKHFNIKIADFGISRVIDF---NFNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

KVLLELIGG
 .| ||. |
MMLYELATG

Kinase IRAKm_q-2.AA S_TKc 468-752 22 1.7e-33 118.53 SMART 1-231 (231) Show / Hide
Range on Protein: 468-752
Range on HMM: 1-231/231
Sequence Identity: 22% (68 aa)

KGYSTKLGAGGYGSVYKGVLSD-GRVVAVKKLDYSGTQGAKQFVTEIAGIGGISHVNIVKLCGFCIEGATQWLLVYEFMPN--GSLDKWLFEQTSENLW-
     |.| |..|.|||..  . ||.||.|...       ...  ||.      | ||||| ... .  .   .| |....  |.| . . .. .. |  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSWQQRIDIALGMAQGLVYLHEECREPILHLDIKPQNILLDTEFVAKVADFGMAKLLENRNETQVMTTMRGTPGYMAPEWLTHFMATK-RCDVYSYGKV
 ..  .   ..  ....| |.|.     |.| |.||.|||||.  . |..|||.|..|         ||. ||| ||||| |     .| .||..| | .
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LLELIGGRR----NIDLSKAVNSGDNTQPDESWYFPTWVVNQVEKGNFLEVIDERVRASASENYHQAKKMVHLALWCIQDNADARPSMRTIVE-------
| |.. |.        . | .                                              . . ..   | | . . ||.   . .       
LYEMLCGYPPFPQMQMMFKKIG--------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

--VL
   .
HPWF

Kinase IRAKm_q-2.AA Dicty4 473-665 31 8.1e-32 103.52 In-house 6-210 (277) Show / Hide
Range on Protein: 473-665
Range on HMM: 6-210/277
Sequence Identity: 31% (65 aa)

KLGAGGYGSVYKGVLSDGRVVAVKKL--DYSG--TQGAKQFVTEIAGIGGISHVNIVKLCGFCI---EGATQWLLVYEFMPNGSLDKWLFE---QTSENL
..| |..|.||||    |  ||||||  .  .      . |  |..  . |.| ||... | |.         . | |.|| |.| . |        .. 
RIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSI

WLSWQQRID---IALGMAQGLVYLHE-ECREPILHLDIKPQNILLDTEFVAKVADFGMAKLLENRNETQV-MTTMRGTPGYMAPEWLTHFMATKRCDVYS
 |.|  ..    .|.  |.|. .||.  ..  |.|.|.|. |.| |  ...||.||| ...     . .  ..|. |||..|||| . |   .   ||||
KLDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYS

YGKVLLEL
.| || |.
FGIVLWEI

Kinase IRAKm_q-2.AA STE 470-669 22 1.5e-31 108.75 In-house 1-265 (359) Show / Hide
Range on Protein: 470-669
Range on HMM: 1-265/359
Sequence Identity: 22% (63 aa)

YST--KLGAGGYGSVYKGVLSD----------------GRVVAVKKLDYSGTQG-----------------AKQFVTEIAGIGGIS--HVNIVKLCGFCI
.    |.| |..|.|||..  .                |...|.|.....  .                   .|.  ||      .  | ||||  | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EGA------TQWLLVYEFMPNGSLDKWLFE--QTSENL--------WLSWQQRIDIALGMAQG-LVYLHEECREPILHLDIKPQNILLDTEFVAKVADFG
 .       ..  .. |.|..||||. . .   . ..|        ... .| . |.    .| | |||.     | | ||||.||||     .| .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

MAKLLEN--------------RNETQVMTTMRGTPGYMAPEWLTHFM------ATKRCDVYSYGKVLLELIGGR
 .. |..               .  |  .|. ||| .|||| ..          . .||..| | ...|.. |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK

Kinase IRAKm_q-2.AA RIPK 474-669 26 8.9e-29 95.17 In-house 1-225 (290) Show / Hide
Range on Protein: 474-669
Range on HMM: 1-225/290
Sequence Identity: 26% (61 aa)

LGAGGYGSVYKGVLSDGRVVAVKKLDYSGT-------QGAKQFVTEIAGIGGISHVNIVKLCGFCIEG--ATQWL---LVYEFMPNGSLDKWLFEQTS-E
.| || | |.| .  . .....||   .         |  ..   | .    . . .||.. |||..   . .     .| |.|.|||| . |  ...  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

NLWLSWQQRIDIALGMAQGLVYLHEECRE-PILHLDIKPQNILLDTEFVAKVADFGMAKLLENRNETQ---------VMTTMR--GTPGYMAPEWLT--H
.  . |  |  .   .. |  |||  .   ||.|.| ||.|||.| .| .|.|||| |. ..    .|          |.     ||  ||.|| .    
HHPDPWPLRCRMIHEISCGMCYLH--SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

FMA----TKRCDVYSYGKVLLELIGGR
  .    |.  ||||.. |. |.  ..
KKPIKVVTPKYDVYSFAIVMWEVLTQK

Kinase IRAKm_q-2.AA Pkinase_Tyr 473-659 28 4e-26 89.11 Pfam 6-201 (270) Show / Hide
Range on Protein: 473-659
Range on HMM: 6-201/270
Sequence Identity: 28% (57 aa)

KLGAGGYGSVYKGVLS-----DGRVVAVKKL-DYSGTQG--AKQFVTEIAGIGGI-SHVNIVKLCGFCI-EGAT-QWLLVYEFMPNGSLDKWLFEQTSEN
|||.| .|.||||..      ..  ||||.| ...  .    . |  |..    . .| |||.| | |. .|   |...| |.||.|.|.. | .. ...
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDK

LWLSWQQRIDIALGMAQGLVYLHEECREPILHLDIKPQNILLDTEFVAKVADFGMAKLLENRNET-QVMTTMRGTPGYMAPEWLTHFMATKRCDVYSYG
  |. .. .....  |.|. ||..     . | |.   |.|.. ..|.|..|||.|....|  .  .. .  .     |||| . .   |   ||.|.|
QPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFG

Kinase IRAKm_q-2.AA TK-Unique 473-665 26 1.5e-25 85.17 In-house 6-232 (294) Show / Hide
Range on Protein: 473-665
Range on HMM: 6-232/294
Sequence Identity: 26% (61 aa)

KLGAGGYGSVYKGVLSD-------GRVVAVKKLD-YSGTQGAKQFVTEIAGIGGIS-HVNIVKLCGFCIEGATQWLLVYEFMPNGSLDKWLFEQTSE---
..| | .| |..| ..         ..||||.|  ..  .  ..|  ||.    .  | |||...| |..   .|....|..|.|.|.. | .   .   
VIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQ

-----NLW--------------LSWQQRIDIALGMAQGLVYLHE---ECREPILHLDIKPQNILLDTEFVAKVADFGMAKLLENRNETQVMTTMRGTPG-
     ||               .| .. . .| . |.|. ||..   ..     | |.   |.||   .|.|..|||||. ... |. ..|.. .|.   
HQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI----VHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIPI

-YMAPEWLT--HFMA-TKRCDVYSYGKVLLEL
 .|||| |   | |. | . ||.|.| .. |.
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEI

Kinase IRAKm_q-2.AA TyrKc 471-752 21 5.2e-24 87.02 SMART 4-280 (280) Show / Hide
Range on Protein: 471-752
Range on HMM: 4-280/280
Sequence Identity: 21% (68 aa)

STKLGAGGYGSVYKGVLSDGRVVAVKKLD-YSGTQGAKQFVTEIAGIGGI--SHVNIVKLCGFCIEGA------TQWLLVYEFMPNGSLDKWLFEQTSEN
  ||| | .| ||||...  . ||||.|  ..     . |  |.     .  .| |||.| | |...        . ..| |.||.|.|.. | .   . 
GKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

LWLSWQQRIDIALGMAQGLVYLHEECREPILHLDIKPQNILLDTEFVAKVADFGMAKLLENR----NETQVMTTMR--GTPG-----YMAPEWLTHFMAT
  |.... .....  |.|  |||.    .. | |.   |.|.. ....|..|||... ...      .... ...   |. .      |||| . . . |
--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KRCDVYSYGKVLLELI-------GG-----RRNIDLSKAVNSG-DNTQPDE----SWYFPTWVVNQVEKGNFLEVIDERVRASASENYHQAKKMVHLALW
   ||.|.| .. |.         |       |... . | .|    ||..    |                            .   .  ..|  . ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------F--VCCPDEMYQIMKQ

CIQDNADARPSMRTIVEVL
| . ... ||....|.| .
CWHEDPEDRPTFSEIHECF

Kinase IRAKm_q-2.AA TK-Unique 734-752 42 0.000236 11.06 In-house 276-294 (294) Show / Hide
Range on Protein: 734-752
Range on HMM: 276-294/294
Sequence Identity: 42% (8 aa)

CIQDNADARPSMRTIVEVL
|.|.... ||| |.|. .|
CWQWEPEERPSFRQIKHRL

Kinase IRAKm_q-2.AA MLK 734-752 42 0.001065 8.86 In-house 273-291 (291) Show / Hide
Range on Protein: 734-752
Range on HMM: 273-291/291
Sequence Identity: 42% (8 aa)

CIQDNADARPSMRTIVEVL
| ....  |||.| ||. |
CWNQDPHKRPSFRQIVQHL

Kinase IRAKm_q-2.AA Dicty4-Unclassified 730-752 34 0.011207 4.95 In-house 241-263 (263) Show / Hide
Range on Protein: 730-752
Range on HMM: 241-263/263
Sequence Identity: 34% (8 aa)

LALWCIQDNADARPSMRTIVEVL
|  ||  .    ||.|  |.. |
LIKWCWHNDPNKRPTMNQIIQYL

Kinase IRAKm_q-2.AA LISK 730-752 34 0.013274 4.05 In-house 274-296 (296) Show / Hide
Range on Protein: 730-752
Range on HMM: 274-296/296
Sequence Identity: 34% (8 aa)

LALWCIQDNADARPSMRTIVEVL
|...|.  . . |||  .||..|
LCFDCCKYDPKNRPSFKEIVQWL

Kinase IRAKm_q-2.AA IRAK 724-752 27 0.030293 3.96 In-house 289-317 (317) Show / Hide
Range on Protein: 724-752
Range on HMM: 289-317/317
Sequence Identity: 27% (8 aa)

AKKMVHLALWCIQDNADARPSMRTIVEVL
.|.|  .|. |    |  |..|.  .. |
EKEMCQCACCCGHHRANRRCDMAWVMQQL

Kinase IRAKm_q-2.AA Pkinase_Tyr 732-752 28 0.116973 6.24 Pfam 250-270 (270) Show / Hide
Range on Protein: 732-752
Range on HMM: 250-270/270
Sequence Identity: 28% (6 aa)

LWCIQDNADARPSMRTIVEVL
. | . ... ||... |.| |
KQCWHYDPEDRPTFSEIHEQL

Kinase IRAKm_q-2.AA TKL-Unique 734-752 31 0.142238 1.54 In-house 272-290 (290) Show / Hide
Range on Protein: 734-752
Range on HMM: 272-290/290
Sequence Identity: 31% (6 aa)

CIQDNADARPSMRTIVEVL
|  .. . |||  .|.. |
CWHHDPSQRPSFDEIIHRL