Gene IRAKm_n-1 (S.moellendorffii)

IRAKm_n-1

Species: S.moellendorffii
Alias: IRAKm_n-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKm

Sequence

Name Sequence Type Origin Length Description Download
IRAKm_n-1.AA Protein None 891 None Fasta, JSON
IRAKm_n-1.NA RNA None 2676 None Fasta, JSON
IRAKm_n-1.kin_dom Protein Kinase Domain None 206 None Fasta, JSON

Protein domain

Protein domains of IRAKm_n-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKm_n-1.AA B_lectin 123-218 26 1.8e-08 30.69 Pfam 4-137 (137) Show / Hide 
Range on Protein: 123-218
Range on HMM: 4-137/137
Sequence Identity: 26% (35 aa)

PVWIANRG---GAV-DDN----ATLLLTPQNGKIILLDSS-H-NF--RWGP-NSEAIAG------VELLESGNLGFFT-AQ--GAVVWQS--FELPQEVI
.|| |||      | |      .|| ..  .|  .|.|..        |   |. . .|      .....||||  .. ..  ..|.|||  |. |   .
VVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPTDTW

LPGQALKP------GMQ----LTSS--GT--NRS
|||. |        .|     |||.  .|  . |
LPGMKLGWDNNVTIYMNWIGYLTSWKSNTNYDPS
B_lectin IRAKm_n-1.AA B_lectin 73-194 21 3.8e-05 7.57 SMART 1-126 (126) Show / Hide 
Range on Protein: 73-194
Range on HMM: 1-126/126
Sequence Identity: 21% (30 aa)

QRHDLEDVT--SDNGTFA--LAFFHLHGGFYLAVVLQAPGHGEISSSSSSSSAIPVWIA--NRGGAVDD---NATLLLTPQNGKIILLDSSHNFRWGPNS
. . ... |  |.|..|   | || . . ... ..     ...|| .       .|| |  ||.. | |   ...| ... .| ....|   .  |  |.
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQWCNGIW-----YKNISNK----QRTVVWVAQPNRDNPVHDGNNSCYLTMQS-DGNLVIYD--NRPVWSSNT

E-AIAGV--ELLESGNLGFFTAQ----GAVVWQSFELP
  .  ..  .|...||.  .       | ..||||. |
TRNNGNYVAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
PAN_AP IRAKm_n-1.AA PAN_AP 393-471 17 0.000797 16.01 SMART 1-85 (85) Show / Hide 
Range on Protein: 393-471
Range on HMM: 1-85/85
Sequence Identity: 17% (16 aa)

YVNHHFLNVSGVSYFAVPLAVP-----DMRGASREKCAAACRWNCSCAALFFDNRTGECFFVL-DEILGSLT------IDPARSSSMIAML
   ..|. ......     .        .  .| | |...|..|||| .  ..| |..| .   |  ||. .      . |... .    .
CCDDCFVRMPNMKL----FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN-TKGCHLWSWDSHLGDPRQFKRFMKFPNQGVDYYEKN
Kinase IRAKm_n-1.AA TKL 571-844 20 3e-60 206.48 In-house 1-364 (364) Show / Hide 
Range on Protein: 571-844
Range on HMM: 1-364/364
Sequence Identity: 20% (81 aa)

LGAGGFGSVYEGFLEDGK--------RSIAVKKLEGASAQGA---------------------------RQFIAEVATIGSISHINVVKLCGFCVEGCH-
.| |||| || | .            . .||||.   . .                              ... |.  . ...| |.|.. |.| .. . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RMLVYEFMPNGSLDRWLFVSNQTPEHPRGVLSWDRRVEIALGTARGLAYLHE----ECREP--IIHLDVKPQNILLDERFV-------
             ..|.|..|.|||   |               |..|. .||..|||..|||      |. .  ||| | |..|||.|| .        
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMY

-------AKVADFGMSKLLGGRD----------------VSHVVTCVRG-TPGYLAPEWLLHS----------------IATKKCDVYSFGMVLLEIIGG
       .|..||| |. . ..                 ...  |. .. ||...||| |  .                 ...||||||||.|| ||. .
NPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTR

RKNLEVSRMNSDLAWYFPAWVVNEVR---EGRLMEIVDERIRALVS------------EKAAAQMIRIALWCVQESAASRPTMPEIVQMI
..            .| .     ...   |  .| ..|.. | ..             . .  .|.... .| .. . .||.. ||.. .
CR-----------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKm_n-1.AA IRAK 565-771 38 5e-48 165.87 In-house 1-222 (317) Show / Hide 
Range on Protein: 565-771
Range on HMM: 1-222/317
Sequence Identity: 38% (86 aa)

WGFSRKLGAGGFGSVYEGFLEDGKRSIAVKKL-EGASAQGA---RQFIA---EVATIGSISHINVVKLCGFCVEGCHRMLVYEFMPNGSL-DRWLFVSNQ
.  ....| |||| || | .       ||||| |.|. .     ..| .   |. .  .. | |.| | |.| |.    |||..|||||| ||     .|
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

TPEHPRGVLSWDRRVEIALGTARGLAYLHEEC-REPIIHLDVKPQNILLDERFVAKVADFGMSKLL---GGRDVSHV----VTCVRGTPGYLAPEWLL--
.|  |   ||| .|..|..|||.|. .||.     |||| |.|. |||||..|..| .|||.       ...  . .    .  ||||  |..|| .   
CPPKP---LSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDP

HSIATKKCDVYSFGMVLLEIIGGRK
  . ||| |||||| ||||.. |..
QGQLTKKTDVYSFGIVLLEVLTGCR
Pkinase IRAKm_n-1.AA Pkinase 565-844 21 5.5e-48 170.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 565-844
Range on HMM: 1-293/293
Sequence Identity: 21% (69 aa)

WGFSRKLGAGGFGSVYEGFLEDGKRSIAVKKLEGASAQG--ARQFIA--EVATIGSISHINVVKLCGFCVEGCHRMLVYEFMPNG----SLDRWLFVSNQ
. . ||.|.|.||.||..   .  .  |||...  ..     .. .   |..   ...| |.|.| ... .. |  .| |....|    .| ... .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

TPEHPRGVL--SWDRRVEIALGTARGLAYLHEECREPIIHLDVKPQNILLDERFVA----KVADFGMSKLLGGRDVSHVVTCVRGTPGYLAPEWLL-HSI
   . .|..  |..    ... ..|||.|.|..    ||| |.||.|||.|.. .     |..||| .|..     ..  | . |||.|.|||... .. 
---WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQY

ATKKCDVYSFGMVLLEIIGGRKNLEVSRMNSDLAWYFPAWVVNEVREGRLMEIVDERIRALVSEKAA-----------------------AQMIRIALWC
 ..|.|..|.| .| | . ||               ||  . .. .  . |...... .. ...                            .. .  ||
YGPKVDMWSCGCILYEMLCGR-------------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

VQESAASRPTMPEIVQM--I
 .   ..||| ..|.|   .
LCKDPKKRPTAEQILQHPWF
Kinase IRAKm_n-1.AA MLK 565-767 28 4.3e-40 136.8 In-house 1-230 (291) Show / Hide 
Range on Protein: 565-767
Range on HMM: 1-230/291
Sequence Identity: 28% (68 aa)

WGFSRKLGAGGFGSVYEGFLEDGK---RSIAVKKLE------GASAQGARQFIAEVATIGSISHIN----VVKLCGFCVE-GCHRMLVYEFMPNGSLDRW
  |....|.|.||.|. |         . .|||. .      . .   ...|  |.     .|| |    .... | | . .||  .| |....||| . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LFVSNQTPE---HPRG---VLSWDRRVEIALGTARGLAYLHEECREPIIHLDVKPQNILLDE------RFVAKVADFGMSKLLGGRDVSHV---VTCVRG
|   .  ..   |.     | . |  . .||  |||..|||.. . |||| | |..|||.||        ..|..||| |     ||...     .. .|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS-----RDWHQMCTNMMSNAG

TPGYLAPEWL---LHSIATKKCDVYSFGMVLLEII
|. . ||| .    ..  ..||||.|.|.|| |..
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEML
Kinase IRAKm_n-1.AA TKL-Unique 567-767 30 2.1e-36 125.94 In-house 1-222 (290) Show / Hide 
Range on Protein: 567-767
Range on HMM: 1-222/290
Sequence Identity: 30% (67 aa)

FSRKLGAGGFGSVYEGFLEDGKRSIAVKK-LEGASAQGARQFIAEVATIGSIS-HINVVKLCGFCV----EGCHRMLVYEFMPNGSLDRWLF--VSNQTP
|. |.|.||.|.|| |     .  | ... .|. | .  . |. || ..  .  |.|.|.. |.|.       .. .| |..| |||.  |     |   
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

EHPRGVLSWDRRVEIALGTARGLAYLHEECREPIIHLDVKPQNILLDER-----FVAKVADFGMSKLLGGRDVSHVV-------TCVRGTPGYLAPEWLL
  .   |.. .|| .|.  |.|. ||| .    |||.| |..|.|.|..     . .|..||| ||..  .. . .        . . |.. ..||| | 
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

H--SIATKKCDVYSFGMVLLEII
   .  ..|.||||||.|| ||.
MNFCQYSEKSDVYSFGIVLWEIA
Kinase IRAKm_n-1.AA Dicty4-Unclassified 567-769 34 3.4e-35 117.96 In-house 3-204 (263) Show / Hide 
Range on Protein: 567-769
Range on HMM: 3-204/263
Sequence Identity: 34% (73 aa)

FSRKLGAGGFGSVYEGFLEDGKRSIAVKKLEGASAQGAR-----QFIAEVATIGSISHINVVKLCGFCVEG-CHR---MLVYEFMPNGSLDRWLFVSNQT
  . .| | |  |. |    ||  .||||.   . . .|      | .||.  |||.| | ||. | |.    |.   . | |||. | |   . | .  
IDQFIGKGHFSKVHKGNWK-GK-DVAVKKFNENKFK-FREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNL---FEVIHSK

PEHPRGVLSWDR--RVEIALGTARGLAYLHEECREPIIHLDVKPQNILLDERFVAKVADFGMSKLLGGRDVSHVVTCVRGTPGYLAPEWLLHSIATKKCD
|      .. |    . .|.  |.|...||   |. .|| |.|  |||.|  | .|.||||.|      |     | . |||   .|| | |   . | |
PSEQQQPIKLDDTLIIKYAFDIAQGMQHLH--TRN-FIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESYNQKSD

VYSFGMVLLEIIGG
|||..|.| | . |
VYSYAMMLYELATG
Kinase IRAKm_n-1.AA LISK 570-771 28 8.1e-35 110.41 In-house 1-237 (296) Show / Hide 
Range on Protein: 570-771
Range on HMM: 1-237/296
Sequence Identity: 28% (69 aa)

KLGAGGFGSVYEGFLE-DGKRSIAVKKLEG-----ASAQGARQFIAEVATIGSISHINVVKLCGFCVE-GCHRMLVYEFMPNGSLDRWLFVSNQTPEHPR
..| |.||.|| | .  .|.  .|.|...            . .. ||... ...| |.|.  | |..   . ..| |..  | | . |. ...      
EIGKGFFGKVYKGTHRQTGQ-VMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDK----HK

GVLSWDRRVEIALGTARGLAYLHEECREPIIHLDVKPQNILLDER----FVAKVADFGMSKLLGGRDVS-------------------------------
 .|.|. || |||. |.|..|||. .   ||| | | .|.|..|.    . .||.|||  ...  .. |                               
IPLPWPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQ

--HVVTCVRGTPGYLAPEWLLHSIATKKCDVYSFGMVLLEIIGGRK
     |.. |||   ||| || .  . .|||.|||.||.|||...|
RKRRMTIC-GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVK
Kinase IRAKm_n-1.AA Pkinase_Tyr 567-767 28 1.3e-33 114.48 Pfam 3-208 (270) Show / Hide 
Range on Protein: 567-767
Range on HMM: 3-208/270
Sequence Identity: 28% (63 aa)

FSRKLGAGGFGSVYEGFLE----DGKRSIAVKKL-EGASAQG--ARQFIAEVATIGSI-SHINVVKLCGFCV-EGCH--RMLVYEFMPNGSLDRWLFVSN
| .|||.| ||.||.| .     ..|   |||.| |||. .    . |..|...  .. .| |.|.| | |. .| .   ..| |.||.|.|.  |    
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR

QTPEHPRGVLSWDRRVEIALGTARGLAYLHEECREPIIHLDVKPQNILLDERFVAKVADFGMSKLLGGRDVSHVV------TCVRGTPGYLAPEWLLHSI
    .... |.  . .....  |.|..||..     .|| |.   |.|..| .|.|..|||.....   |   ..        .. .    ||| . ...
----EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWM----APECINYGK

ATKKCDVYSFGMVLLEII
 | | ||.||| .. ||.
FTTKSDVWSFGVLMWEIF
Kinase IRAKm_n-1.AA RIPK 571-771 28 2e-33 111.23 In-house 1-226 (290) Show / Hide 
Range on Protein: 571-771
Range on HMM: 1-226/290
Sequence Identity: 28% (68 aa)

LGAGGFGSVYEGFLEDGKRSIAVKKLEGAS------AQGARQFIAEVATIGSISHINVVKLCGFCVEG-----CH-RMLVYEFMPNGSLDRWLFVSNQTP
.| |||| |.  .  . .  .|.|   .         |   . . |..   .. . ..|.. ||| .      |    .| |.|.||||  | | . ..|
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSL--WHFLHTKWP

--EHPRGVLSWDRRVEIALGTARGLAYLHEECRE-PIIHLDVKPQNILLDERFVAKVADFGMSKLLGGRDVSHVVT--C-----------VR-GTPGYLA
  .||   . |. |  .   ...|  |||  .   ||||.| ||.|||.|  | .|.|||| .. ...   ||. .  |            | ||  |..
YQHHP---DPWPLRCRMIHEISCGMCYLH--SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMW---SHSHQDRCNQREVYSMKSKNRWGTLSYMP

PEWLL----HS--IATKKCDVYSFGMVLLEIIGGRK
|| ..     .  ..|.| |||||..|. |.  ...
PEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKH
Kinase IRAKm_n-1.AA Dicty4 567-766 33 3.1e-32 104.95 In-house 3-210 (277) Show / Hide 
Range on Protein: 567-766
Range on HMM: 3-210/277
Sequence Identity: 33% (72 aa)

FSRKLGAGGFGSVYEGFLEDGKRSIAVKKL----EGASAQGARQFIAEVATIGSISHINVVKLCGFCV----EGCHRMLVYEFMPNGSLDRWLFV--SNQ
.  ..| |.||.|| |    ||   |||||    .....     | .||.  ..|.| |.... | |     .    . | |.|| |.| . |    | |
IEQRIGKGSFGEVYKGTWR-GKE-VAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

TPEHPRGVLSWDRRVE---IALGTARGLAYLHE-ECREPIIHLDVKPQNILLDERFVAKVADFGMSK-LLGGRDVSHVVTCVRGTPGYLAPEWLLHSIAT
 .. .   |.| ..     .|. .|||...||.  ..  |||.| |. |.| |. ...||.||| |.    . | .   . . |||.. ||| . |   .
QQSIK---LDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

KKCDVYSFGMVLLEI
 | ||||||.|| ||
EKADVYSFGIVLWEI
Kinase IRAKm_n-1.AA TK 567-766 17 7e-32 103.58 In-house 3-387 (486) Show / Hide 
Range on Protein: 567-766
Range on HMM: 3-387/486
Sequence Identity: 17% (66 aa)

FSRKLGAGGFG---SVYEGFLEDGK-------------------------RSIAVKKLEGASAQGARQFIA--------------EVATIGSIS-----H
. .|||.| ||    ||.| .....                            ||| |   .|. ...|..              |.. .   .     |
LGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHH

INVVKLCGFCVEGC------------HRMLVYEFMPNGS----LDRWLFVSNQTPEH-------------------------------------------
 |.|.| | |..|             . |.| |.||.|.    |. .|  .  .  |                                           
PNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDD

-------------------------PRGVLSWDRRVEIALGTARGLAYLHEE----CREPIIHLDVKPQNILLDERFV-----------AKVADFGMSKL
                         ... |.  ... ...  |.|..|||.         ..| |.   |.|..|. |           .|.||||.|. 
DLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

L---GGRDVSHVVTCVRGTPGY-----------------------------LAPEWLLHSI---------ATKKCDVYSFGMVLLEI
      ||. .    .| ....                             .||| |.. .          | | ||.||| .. ||
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase IRAKm_n-1.AA LRRK 565-767 25 5.1e-31 106.96 In-house 1-276 (351) Show / Hide 
Range on Protein: 565-767
Range on HMM: 1-276/351
Sequence Identity: 25% (72 aa)

WGFSRKLGAGGFG-SVYEGFLED-------------------------GKR-SIAVKKLEGA----------------------------------SAQG
  . ...| |||| .|| . ...                          .. ..|.||..                                    ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

ARQFIAEVATIGSISHINVVKLCGFCVEGCHRMLVYEFMPNGSLDRWLFVSNQTP----EHPRGVLSWDRRVEIALGTARGLAYLHEECREPIIHLDVKP
 | |  ||. . .  | |.|.| ||| .  ....| |..|.|.|.. |. . |..         ..||  . .|||  |.|..|||  .. |||| | |.
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMK---AHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKS

QNILL---D---------ERFVAKVADFGMSKLLGGRDVSH-VVTCVRGTPGYLAPEWLL---HSIATKKCDVYSFGMVLLEII
 ||||   .         .  .||.|||| |  .    . . |.  . |.||..||| .     .  | | |.|||||.| |..
PNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELL
Kinase IRAKm_n-1.AA TyrKc 567-844 24 3.8e-28 100.76 SMART 3-280 (280) Show / Hide 
Range on Protein: 567-844
Range on HMM: 3-280/280
Sequence Identity: 24% (75 aa)

FSRKLGAGGFGSVYEGFLEDGKRSIAVKKLEGASAQGARQFIAEVATIGSI--SHINVVKLCGFCVEG-------CHRMLVYEFMPNGSLDRWLFVSNQT
. .||| | || ||.| .    .  |||.|   .    . |. |     ..  .| |.|.| | |...          |.| |.||.|.|.  |  .  .
LGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PEHPRGVLSWDRRVEIALGTARGLAYLHEECREPIIHLDVKPQNILLDERFVAKVADFGMSKLLGGRD---VSHVVTCVR---GTPG-----YLAPEWLL
       |...  .....  |.| .|||.    ..|| |    |.|..|....|..|||.|. ..  |   .|. .  ..   |. .      .||| . 
-------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

HSIATKKCDVYSFGMVLLEIIGGRKNLEVS-----RMNSDLAWYFPAWVVNEVREGRLMEIVDERIRALVSEK----AAAQMIRIALWCVQESAASRPTM
... | | ||.||| .. ||    .            |..        |.. |..|. |.. ..       .     . . | .| ..| .| ...|||.
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQE--------VIEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQIMKQCWHEDPEDRPTF

PEIVQMI
 ||.. .
SEIHECF
Kinase IRAKm_n-1.AA S_TKc 565-844 23 1.7e-25 91.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 565-844
Range on HMM: 1-231/231
Sequence Identity: 23% (68 aa)

WGFSRKLGAGGFGSVYEGFLEDGKRSIAVKKLEGASAQGARQFIAEVATIGSISHINVVKLCGFCVEGCHRMLVYEFMPN--GSLDRWLFVSNQTPEHPR
. . ||.| |.||.|| .   . .|  |.|..        .... |..   .  | |.||| .....  |  .| |....  |.| . .   .. .. .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI--KKRGRHGLR

GVLSWDRRVEIALGTARGLAYLHEECREPIIHLDVKPQNILLDERFVAKVADFGMSKLLGGRDVSHVVTCVRGTPGYLAPEWLLHSIATKKCDVYSFGMV
 ...  .   ..  ....|.|.|.     ||| |.||.||||||  . |..|||....|         | . ||| |.||| |  .  ..|||..|.| .
FPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCI

LLEIIGGRKNLEVSRMNSDLAWYFPAWVVNEVREGRLMEIVDERIRALVSEKAAAQMIRIALWCVQESAASRPTMPEIVQ---------MI
| | . |.   .      ...  |   .                           ... .   | |   . |||  |. |          .
LYEMLCGYPPFP------QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKm_n-1.AA TK 806-844 12 0.00043 8.77 In-house 450-486 (486) Show / Hide 
Range on Protein: 806-844
Range on HMM: 450-486/486
Sequence Identity: 12% (5 aa)

RIRALVSEKAAAQMIRIALWCVQESAASRPTMPEIVQMI
|. .  .... . . .. . | .. .. |||. ......
RM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAKm_n-1.AA Dicty4-Unclassified 825-844 40 0.000466 9.75 In-house 244-263 (263) Show / Hide 
Range on Protein: 825-844
Range on HMM: 244-263/263
Sequence Identity: 40% (8 aa)

WCVQESAASRPTMPEIVQMI
||  ..   |||| .|.|  
WCWHNDPNKRPTMNQIIQYL
Kinase IRAKm_n-1.AA Dicty4 833-846 37 0.025523 3.74 In-house 262-277 (277) Show / Hide 
Range on Protein: 833-846
Range on HMM: 262-277/277
Sequence Identity: 37% (6 aa)

SRPTMPEIVQM--IEG
.||...||.|    | 
HRPSFEEIIQRRILEH
Kinase IRAKm_n-1.AA IRAK 813-844 21 0.037435 3.63 In-house 286-317 (317) Show / Hide 
Range on Protein: 813-844
Range on HMM: 286-317/317
Sequence Identity: 21% (7 aa)

EKAAAQMIRIALWCVQESAASRPTMPEIVQMI
.. .. |   |. |. . |. |..| . .| .
PNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAKm_n-1.AA MLK 826-844 31 0.068617 2.5 In-house 273-291 (291) Show / Hide 
Range on Protein: 826-844
Range on HMM: 273-291/291
Sequence Identity: 31% (6 aa)

CVQESAASRPTMPEIVQMI
| .. ...||.. .|||  
CWNQDPHKRPSFRQIVQHL
Kinase IRAKm_n-1.AA LRRK 825-846 27 0.150402 1.23 In-house 330-351 (351) Show / Hide 
Range on Protein: 825-846
Range on HMM: 330-351/351
Sequence Identity: 27% (6 aa)

WCVQESAASRPTMPEIVQMIEG
.| |.   .||.. .||. .. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKm_n-1.AA Pkinase_Tyr 824-844 28 0.351895 4.62 Pfam 250-270 (270) Show / Hide 
Range on Protein: 824-844
Range on HMM: 250-270/270
Sequence Identity: 28% (6 aa)

LWCVQESAASRPTMPEIVQMI
. | .. .. |||. ||....
KQCWHYDPEDRPTFSEIHEQL