Gene IRAKm_f (S.moellendorffii)

IRAKm_f

Species: S.moellendorffii
Alias: IRAKm_f
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKm

Sequence

Name Sequence Type Origin Length Description Download
IRAKm_f.AA Protein None 737 None Fasta, JSON
IRAKm_f.NA RNA None 2214 None Fasta, JSON
IRAKm_f.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of IRAKm_f.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKm_f.AA B_lectin 144-212 31 5.1e-17 60.05 Pfam 39-137 (137) Show / Hide 
Range on Protein: 144-212
Range on HMM: 39-137/137
Sequence Identity: 31% (31 aa)

LSDLD-G-NT--VWST-D----PS--NATTIELQESGNLVLR-DAG--DREVWQS--FDNPSDVILEGQKIFT------GQR----LTSSKNRS----S
|.| . |  .  |||| .     .  |... ..|.||||||. |..  .. .|||  ||.|.| .| |.|. .      ...    |||.|. .    |
LYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPTDTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTNYDPS
B_lectin IRAKm_f.AA B_lectin 70-188 31 8.8e-17 63.0 SMART 1-126 (126) Show / Hide 
Range on Protein: 70-188
Range on HMM: 1-126/126
Sequence Identity: 31% (42 aa)

PAPSSPGEKLVSANGTFA--LCFFTFRGTEKSHLSIVIRSANSPNTSAAVVWTA--NRRDPIRGG---GALRWNSTKKSLDLSDLDGNTVWSTDPS---N
  . | |. ||| |..|   |.|||| .     . . |   |..|    ||| |  ||  | ..|   . |. .|    | . |  ...|||.. .   .
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ----WCNGIWYKNISNKQRTVVWVAQPNRDNPVHDGNNSCYLTMQSD-GNLVIYD--NRPVWSSNTTRNNG

ATTIELQESGNLVLRDAG----DREVWQSFDNP
 .. .||..||.|..| .    .. .|||||.|
NYVAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
B_lectin IRAKm_f.AA B_lectin 114-132 30 0.254447 6.11 Pfam 1-26 (137) Show / Hide 
Range on Protein: 114-132
Range on HMM: 1-26/137
Sequence Identity: 30% (8 aa)

SAAVVWTANRR---DPI----RGGGA
.  |||.|||    .|.     .|..
NQTVVWVANRDLTGNPVTDSSNNGNY
Kinase IRAKm_f.AA TKL 417-689 21 1.1e-65 224.47 In-house 1-364 (364) Show / Hide 
Range on Protein: 417-689
Range on HMM: 1-364/364
Sequence Identity: 21% (82 aa)

VGSGGSGTVFQGTFLD---------GTKVAIKKLEN----------------------------TSQGQKEFVAEVNSIGSISHMNIIKLCGFCAERSH-
.||||.|.|..|..           |. ||.||.                              .|. ..... |.... ...| ||... |.| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEFIANGSLDHWLFHDDAASQDSSANFLDWRTRFGIALGVARGLSYLHEESR-----QLIMHLDIKPQNILLDEQFV-------
              .|.|.. .||| | |                |  |. .||..|||..||| .         | | |.|..|||.|| .        
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMY

-------AKIADFGTSKLMASREISQE-----------------TTNVRGTPGYLAPEWLLHS----------------VATKKCDVYSYGMVLLEIIAG
       .||.|||.|. |  .. ..                  | ...|||...||| |  .                 ...||||||.|.|| ||...
NPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTR

RRNLMSSCEDEDLAWYFPALAVKKASQGMIREIYDRRIAGEVE------------EKEGERIARVALWCIQENPAMRPSMESVVKML
.|        .|.  . . ..    .. |.  ..|..   ..             .   ..... . .| ...|  |||.. ..| |
CR------PYYDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase IRAKm_f.AA Pkinase 411-689 20 3e-49 174.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 411-689
Range on HMM: 1-293/293
Sequence Identity: 20% (65 aa)

ANFSSMVGSGGSGTVFQGTFLDGTK-VAIKKLENTSQGQKEFVA-----EVNSIGSISHMNIIKLCGFCAERSHRLLVYEFIANG----SLDHWLFHDDA
  . . .|||..|.|....  .  | ||.|...  ..  .. ..     |.    ...| ||..| ... ...|  .| |.  .|    .| ...     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

ASQDSSANFL--DWRTRFGIALGVARGLSYLHEESRQLIMHLDIKPQNILLDEQFVA----KIADFGTSKLMASREISQETTNVRGTPGYLAPEWLL-HS
    .. . .  ....   ... ..||| |.|..    |.| |.||.|||.|.. .     ||.||| .|..     .. .| . |||.|.|||... ..
----WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQ

VATKKCDVYSYGMVLLEIIAGRRNLMSSCEDEDLAWYFPALAVKKASQGMIREIYDRRIAGEVEEKEG-----------------------ERIARVALW
  ..|.|..|.| .| | . ||               ||       .    .....|.  ..... .                        |    .  |
YYGPKVDMWSCGCILYEMLCGR-------------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

CIQENPAMRPSMESVVKM--L
|.. .|. ||. | ...   .
CLCKDPKKRPTAEQILQHPWF
Kinase IRAKm_f.AA IRAK 412-689 27 1.4e-44 154.38 In-house 2-317 (317) Show / Hide 
Range on Protein: 412-689
Range on HMM: 2-317/317
Sequence Identity: 27% (89 aa)

NFSSMVGSGGSGTVFQGTFLDGTK--VAIKKLEN-----TSQGQKEFVA---EVNSIGSISHMNIIKLCGFCAERSHRLLVYEFIANGSLDHWLFHDDAA
. .   |.|| |.|..|  ...|   .|.||| .     . .  ..| .   |. .  .. | ||  | |.|.||.   |||....||||   |     .
HKDNRIGEGGFGCVYRGQ-WKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRL-----W

SQDSSANF--LDWRTRFGIALGVARGLSYLHEES-RQLIMHLDIKPQNILLDEQFVAKIADFGTSK------LMASREI-SQETTNVRGTPGYLAPEWLL
 || .     | | .|. |..| |.|. .||. .    | | |||. |||||..|..||.|||          . . ..   .|  ||||  |..|| . 
CQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIR

--HSVATKKCDVYSYGMVLLEIIAGRRNLMSS-CEDEDLAWYFPALAVKKAS--------------------QGM-IREIYDRRIAGEVEEKEGERIARV
      ||| |||| | ||||...|.|   .   | . |  .   .. . ..                      | |.|..  . .. ....... .. .
DPQGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQC

ALWCIQENPAMRPSMESVVKML
|. |  .  . |..|. |.. |
ACCCGHHRANRRCDMAWVMQQL
Kinase IRAKm_f.AA MLK 411-615 28 3.9e-41 140.45 In-house 1-233 (291) Show / Hide 
Range on Protein: 411-615
Range on HMM: 1-233/291
Sequence Identity: 28% (68 aa)

ANFSSMVGSGGSGTVFQGTFLDGTK-----VAIKKLE-------NTSQGQKEFVAEVNSIGSISHMN----IIKLCGFCAER-SHRLLVYEFIANGSLDH
 .|.  .|||..| |. |..  ..      ||.|. .        |.  |..|  |..    .|| |    ||.. | |..  .| ..| |....||| .
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLFHDDAASQDS-----SANFLDWRTRFGIALGVARGLSYLHEESRQLIMHLDIKPQNILLDE------QFVAKIADFGTSKLMASREISQETTNVRGTP
 |   .  . |.     ..   |    . .|| .|||..|||.. ...| | |.|..|||.||      . ..||.|||||. . ...  .  .. .||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTY

GYLAPEWL---LHSVATKKCDVYSYGMVLLEIIAGR
 . ||| .    ..  ..||||.|.|.|| |.....
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase IRAKm_f.AA TKL-Unique 413-612 29 1.2e-40 141.04 In-house 1-222 (290) Show / Hide 
Range on Protein: 413-612
Range on HMM: 1-222/290
Sequence Identity: 29% (67 aa)

FSSMVGSGGSGTVFQGTFLDGTKVAIKKLE-NTSQG-Q--KEFVAEVNSIGSIS-HMNIIKLCGFCA----ERSHRLLVYEFIANGSLDHWLF-HDDAAS
|.. .|.||.|.|..|..  |..||||... | ..  .  .||  ||| .  .  | || .. |.|.      ... .| |..  |||.  |        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

QDSSANFLDWRTRFGIALGVARGLSYLHEESRQLIMHLDIKPQNILLDEQ-----FVAKIADFGTSKLMA--SREISQET-----TNVRGTPGYLAPEWL
  .. . |..  |  .|. .|.|. ||| ..   |.|.|.|..|.|.|.      . .||.|||.||. .  ..... |      . . |.. ..||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LH--SVATKKCDVYSYGMVLLEII
    .  ..|.||||.|.|| ||.
RMNFCQYSEKSDVYSFGIVLWEIA
Kinase IRAKm_f.AA Dicty4 412-611 34 7.6e-34 110.39 In-house 2-210 (277) Show / Hide 
Range on Protein: 412-611
Range on HMM: 2-210/277
Sequence Identity: 34% (73 aa)

NFSSMVGSGGSGTVFQGTFLDGTKVAIKKL--ENT---SQGQKEFVAEVNSIGSISHMNIIKLCGFCA----ERSHRLLVYEFIANGSLDHWLFHDDAAS
|. .  |.|. |.|. ||   |..||.|||   |.   .   .|| .||.  ..|.| ||... | |     . .  . | |.   |.| . | ||  . 
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNL-YSLLHDKPSE

QDSSANFLDWRTRFG---IALGVARGLSYLHE-ESRQLIMHLDIKPQNILLDEQFVAKIADFGTSKLMASREISQE-TTNVRGTPGYLAPEWLLHSVATK
| .|   ||| ..     .|. .|||. .||.  ..  | |.|.|. |.| |. ...|..||| |..|   |  .  .. . |||.. ||| . |   . 
QQQSIK-LDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

KCDVYSYGMVLLEI
| ||||.|.|| ||
KADVYSFGIVLWEI
Kinase IRAKm_f.AA Dicty4-Unclassified 433-614 36 1.7e-31 105.09 In-house 22-204 (263) Show / Hide 
Range on Protein: 433-614
Range on HMM: 22-204/263
Sequence Identity: 36% (71 aa)

GTKVAIKKLENTSQGQK-----EFVAEVNSIGSISHMNIIKLCGFC-AERSHR---LLVYEFIANGSLDHWLFHDDAASQDSSANFLDWRTRFGIALGVA
|  ||.||.   .         .| .||   |||.| | .|. | | . |||.     | ||.  | |   . |   . |. .   ||      .|. .|
GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNL-FEVIHSKPSEQQQPIK-LDDTLIIKYAFDIA

RGLSYLHEESRQLIMHLDIKPQNILLDEQFVAKIADFGTSKLMASREIS--QETTNVRGTPGYLAPEWLLHSVATKKCDVYSYGMVLLEIIAG
.|. .||  .| .| | |||  |||.|  | .||||||      ||.|.  .  | . |||   .|| | |   . | |||||.|.| | . |
QGMQHLH--TRNFI-HRDIKSSNILMDKHFNIKIADFG-----ISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATG
Kinase IRAKm_f.AA LRRK 411-616 23 7.2e-31 106.42 In-house 1-281 (351) Show / Hide 
Range on Protein: 411-616
Range on HMM: 1-281/351
Sequence Identity: 23% (68 aa)

ANFSSMVGSGGSG-TVFQGTFLD---------------------------GTKVAIKKLENT-----------------------------------SQG
  . ...|.||.| .|..... .                           ...|||||.. .                                   .  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

QKEFVAEVNSIGSISHMNIIKLCGFCAERSHRLLVYEFIANGSLDHWLFHDDAASQDSSAN-FLDWRTRFGIALGVARGLSYLHEESRQL--IMHLDIKP
  ||  ||  . .  | ||..| |||   ... .| |.. .|.|.| |..    .. .     ..| ..  ||| .|.|. |||   ..   | | | |.
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGF-HFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKS

QNILL---D---------EQFVAKIADFGTSKLMASREISQE-TTNVRGTPGYLAPEWLL---HSVATKKCDVYSYGMVLLEIIAGR-R
 ||||   .         .. .|||||||.|  |    .  . .  . |.||..||| .     .. | | |.||.||.| |.. .. .
PNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH
Kinase IRAKm_f.AA TK 411-611 16 3.1e-28 91.15 In-house 1-387 (486) Show / Hide 
Range on Protein: 411-611
Range on HMM: 1-387/486
Sequence Identity: 16% (64 aa)

ANFSSMVGSGGSG---TVFQGTFLDG--------------------------TKVAIKKLENT-SQGQKEFVA--------------EVNSIGSIS----
  .    |.|  |   .|..|.  ..                          |.||.| |  . .. |.|| .              |.. .   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HMNIIKLCGFCAER------------SHRLLVYEFIANGS----LDHWLFHDDA---ASQDSSAN----------------------------------
 | ||..| | | .              . ..| |. ..|.    |...|   .     .||...|                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------FLDWRTRFGIALGVARGLSYLHEE----SRQLIMHLDIKPQNILLDEQFV-----------AKIADFGTS
                              .|. ...  ... .|.|..|||.       | . | |.   |.|..|. |           .|||||| |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

KLM---ASREISQETTNVRGTPGY-----------------------------LAPEWLLHSV---------ATKKCDVYSYGMVLLEI
. .    .|.| ...  .| ....                             .||| |.. |          | | ||.|.| .. ||
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase IRAKm_f.AA TK-Unique 411-611 24 3.2e-27 91.0 In-house 1-232 (294) Show / Hide 
Range on Protein: 411-611
Range on HMM: 1-232/294
Sequence Identity: 24% (56 aa)

ANFSSMVGSGGSGTVFQGTFLDGT-------KVAIKKLENTSQGQK--EFVAEVNSIGSIS-HMNIIKLCGFCAERS-HRLLVYEFIANGSLDHWLFHDD
 .. . .|.|  |.|. |..  ..       .||.|.|.  .....  .|  | .   ..  | ||....| | . .   ....|....|.|.| |    
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

AA--SQ---------------DSSANFLDWRTRFGIALGVARGLSYLHEESRQLIMHLDIKPQNILLDEQFVAKIADFGTSK-LMASREISQETTNVRGT
 |  ..               . . .... .. . .| ..|.|..||..  |. | | |.   |.|| | .|.||.||| .. ... ...| ...  |  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQ-RKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

PGYLAPEWLL--HSVA-TKKCDVYSYGMVLLEI
  ..||| |.  | .. | | ||.|.| .. ||
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEI
Kinase IRAKm_f.AA S_TKc 411-696 22 8e-26 93.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 411-696
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

ANFSSMVGSGGSGTVFQGTFLD-GTKVAIKKLENTSQGQKEFVAEVNSIGSISHMNIIKLCGFCAERSHRLLVYEFIAN--GSLDHWLFHDDAASQDSSA
  .   .|.|. |.|....  . | .||||..       . .  |..   .  | ||.|| ... . .|  .| |.. .  |.| . . .      .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR--F

NFLDWRTRFGIALGVARGLSYLHEESRQLIMHLDIKPQNILLDEQFVAKIADFGTSKLMASREISQETTNVRGTPGYLAPEWLLHSVATK-KCDVYSYGM
 |   ..|| ..  ....| |.|.   . |.| |.||.||||||  . ||.||| ....         | . ||| |.||| |     .| |||..| | 
PFPE-HARF-YMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

VLLEIIAGRRNLMSSCEDEDLAWYFPALAVKKASQGMIREIYDRRIAGEVEEKEGERIARVALWCIQENPAMRPSMESVVK--MLEGLEEVL
.| | ..|.         .. . .   .                           .        | | .|. ||.   . .  ..  . . .
ILYEMLCGYPPFP-----QMQMMFKKIG--------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKm_f.AA DRK 417-612 33 9e-25 80.85 In-house 7-196 (258) Show / Hide 
Range on Protein: 417-612
Range on HMM: 7-196/258
Sequence Identity: 33% (67 aa)

VGSGGSGTVFQGTFLDGTKVAIKKLENTSQG----QKEFVAEVNSIGSISHMNIIKLCGFCAERSHRLLVYEFIANGSLDHWLFHDDAASQDSSANFLDW
.| |. | || ||   ||.||.|.| |         .||  |.| .    | ||.   | | . .  . . |..  |||   | ||.. .       .||
IGRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNIL-HDESIE-------MDW

RTRFGIALGVARGLSYLHEESRQLIMHLDIKPQNILLDEQFVAKIADFGTSKLMASREISQETTNVRGTPGYLAPEWLLHSVATKKCDVYSYGMVLLEII
  .  ... .|.|. |||  .   |.| | |  | | || .  |.|||| |      .    .    |||.  ||| |     | | ||||.. || |..
PLMKQMMFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase IRAKm_f.AA TyrKc 411-689 20 6.7e-23 83.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 411-689
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

ANFSSMVGSGGSGTVFQGTFLDGTKVAIKKLENTSQGQKEFVAEVNSIGSI--SHMNIIKLCGFCAER-------SHRLLVYEFIANGSLDHWL-FHDDA
  .  . |.|  |.|..||    ..||.|.| . .  ...|  | .   ..  .| ||..| | | .           ..| |. ..|.|.. |  | . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

ASQDSSANFLDWRTRFGIALGVARGLSYLHEESRQLIMHLDIKPQNILLDEQFVAKIADFGTSKLMASR---EISQETTNVR---GTPG-----YLAPEW
         | ...   ... .|.| .|||.     . | |.   |.|..|....||.||| |.   .      |...  ..   |. .      .||| 
---------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LLHSVATKKCDVYSYGMVLLEIIAGRRNLMSS-----CEDEDLAWYFPALAVKKASQGMIREIYDRRIAGEVEE-----KEGERIARVALWCIQENPAMR
. ... | | ||.|.| .. ||        .      ......        ...  ||. ... .        .        |    . ..| .|.|..|
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV--------IEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQ-IMKQCWHEDPEDR

PSMESVVKML
|... ... .
PTFSEIHECF
Kinase IRAKm_f.AA Pkinase_Tyr 411-531 23 9.5e-18 60.74 Pfam 1-129 (270) Show / Hide 
Range on Protein: 411-531
Range on HMM: 1-129/270
Sequence Identity: 23% (31 aa)

ANFSSMVGSGGSGTVFQGTFL-----DGTKVAIKKL-ENTSQGQ---KEFVAEVNSIGSI-SHMNIIKLCGFCA-ERSH--RLLVYEFIANGSLDHWLFH
  |  . |.|  |.|..||       ....||.|.| |.... |   ..| .|..   .. .| ||..| | |  .. .   ..| |. ..|.|.. |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

DDAASQDSSANFLDWRTRFGIALGVARGLSYLHE
       .. . |.  .  .... .|.|..||..
HR-----EDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase IRAKm_f.AA DRK 671-691 42 2e-06 17.54 In-house 238-258 (258) Show / Hide 
Range on Protein: 671-691
Range on HMM: 238-258/258
Sequence Identity: 42% (9 aa)

CIQENPAMRPSMESVVKMLEG
|  |.|  ||||. ... || 
CWNEDPQHRPSMQECLERLEA
Kinase IRAKm_f.AA Pkinase_Tyr 546-612 29 4e-06 21.34 Pfam 141-208 (270) Show / Hide 
Range on Protein: 546-612
Range on HMM: 141-208/270
Sequence Identity: 29% (20 aa)

NILLDEQFVAKIADFGTSKLMASREIS-QETTNVRGTPGYLAPEWLLHSVATKKCDVYSYGMVLLEII
|.|..|..|.||.||| .... . .   . ... .     .||| . ... | | ||.|.| .. ||.
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIF
Kinase IRAKm_f.AA TK 662-689 21 1.9e-05 13.43 In-house 459-486 (486) Show / Hide 
Range on Protein: 662-689
Range on HMM: 459-486/486
Sequence Identity: 21% (6 aa)

ERIARVALWCIQENPAMRPSMESVVKML
| .... . | ...|. ||... ....|
EEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAKm_f.AA Dicty4-Unclassified 670-689 35 6.8e-05 12.66 In-house 244-263 (263) Show / Hide 
Range on Protein: 670-689
Range on HMM: 244-263/263
Sequence Identity: 35% (7 aa)

WCIQENPAMRPSMESVVKML
||  . |  ||.|. ... |
WCWHNDPNKRPTMNQIIQYL
Kinase IRAKm_f.AA TK-Unique 671-689 36 8.6e-05 12.6 In-house 276-294 (294) Show / Hide 
Range on Protein: 671-689
Range on HMM: 276-294/294
Sequence Identity: 36% (7 aa)

CIQENPAMRPSMESVVKML
|.|..| .||| ......|
CWQWEPEERPSFRQIKHRL
Kinase IRAKm_f.AA Dicty4 670-691 37 0.000198 10.88 In-house 254-277 (277) Show / Hide 
Range on Protein: 670-691
Range on HMM: 254-277/277
Sequence Identity: 37% (9 aa)

WCIQENPAMRPSMESVVKM--LEG
||  ..|  |||.| ...   || 
WCWDHDPQHRPSFEEIIQRRILEH
Kinase IRAKm_f.AA LRRK 670-691 36 0.000848 9.3 In-house 330-351 (351) Show / Hide 
Range on Protein: 670-691
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

WCIQENPAMRPSMESVVKMLEG
.| |..|  ||.....|| |. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKm_f.AA MLK 671-689 36 0.000959 9.02 In-house 273-291 (291) Show / Hide 
Range on Protein: 671-689
Range on HMM: 273-291/291
Sequence Identity: 36% (7 aa)

CIQENPAMRPSMESVVKML
| ...|. |||. ..|. |
CWNQDPHKRPSFRQIVQHL
Kinase IRAKm_f.AA Pkinase_Tyr 662-689 21 0.004267 11.11 Pfam 243-270 (270) Show / Hide 
Range on Protein: 662-689
Range on HMM: 243-270/270
Sequence Identity: 21% (6 aa)

ERIARVALWCIQENPAMRPSMESVVKML
. | .. . | ...|..||... .. .|
DEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase IRAKm_f.AA TKL-Unique 671-689 31 0.142238 1.54 In-house 272-290 (290) Show / Hide 
Range on Protein: 671-689
Range on HMM: 272-290/290
Sequence Identity: 31% (6 aa)

CIQENPAMRPSMESVVKML
|   .|  ||| ..... |
CWHHDPSQRPSFDEIIHRL