LLEC_f-2

Species: S.moellendorffii
Alias: LLEC_f-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LLEC

Sequence

Name Sequence Type Origin Length Description Download
LLEC_f-2.AA Protein None 646 None Fasta, JSON
LLEC_f-2.NA RNA None 1941 None Fasta, JSON
LLEC_f-2.kin_dom Protein Kinase Domain None 203 None Fasta, JSON

Protein domain

Protein domains of LLEC_f-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Lectin_legB LLEC_f-2.AA Lectin_legB 20-246 32 4.4e-49 174.17 Pfam 12-268 (268) Show / Hide
Range on Protein: 20-246
Range on HMM: 12-268/268
Sequence Identity: 32% (88 aa)

SAQ----PHLALLNDATIAQSGDLWLT-SDQS------PRSTGRAMHDRAIQI---CNTTAG----FSTSFVFSIQNS---TATRGDGLAFIISGNL--L
| |    . | |  |||.. .| | ||  . .      ..|.|.| .   |..    ... |    |||||||.|.|    . . |.|.||.|. .    
SNQCPSWSNLTLQGDATVHPNGALQLTPNVTNNPPPQPTNSMGHAFYPKPIHFWEDWDSSTGKVASFSTSFVFAIYNIPSYNTNGGHGMAFFIAPSDTQN

PAPSGSSGSWLGLFDPAMDR-ERSNKLVAVEFDSVHNPELQDIND--DHVGVDINQIRSQVSPTFESDAG---------NRVDLHDSSANVSAWIEYDAV
|  . ||| .||||.|  ..   ||  |||||| ..|||..|..|  .|||.|.| ||| .|     .||         ...|| .   .. .||.||. 
PPGA-SSGQYLGLFNPTNNGDNPSNHFVAVEFDTFQNPEFNDWDDNYNHVGIDVNSIRSVKS----EPAGYYDDDDGRFVNWDLNSYGKPMQVWIDYDGS

KHSLVVFVARN----SRRRPAAPLVPPQPVNLCEEAAVEGAVFVGFSAAT-GDLSRDVHIVHAWNFS
.  | | .| .    .  .|  ||.  ..|.| .   ..  ..|||||.| |.     | ...|.||
SKQLNVTLAYPWTNMA-FKPKRPLL-SWSVDLSQ--VLPDWMYVGFSASTGGN-YTESHYILSWSFS

Kinase LLEC_f-2.AA TKL 344-602 20 2.4e-56 193.53 In-house 1-364 (364) Show / Hide
Range on Protein: 344-602
Range on HMM: 1-364/364
Sequence Identity: 20% (77 aa)

LGSGGFGNVYAGLLPG--------DGSPVAVKRIGENSRQGERE-------------------------FLAEVEIITKLS--HRNLVHLRG--------
.|||||| || | . |        .| .||||.. ... . . .                         |  |.||  ...  | |.|.. |        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-WCCR----SRELLLVYEFMPNGS-LDKAIATNSSLDWSKRYEIICGLAAALLYLHE----ECEER--IVHRDVKPSNVMLDAGFN--------------
 .|..    . .| .|.|..|.|| |.  .       |..|  .. . | .. |||      |     |.||| |..|...|  ..              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

ARLGDFGLARLIDRKREARTTA------------------IAGTFGYLAPELNI----------------TGQCTTASDVYSFGIVLLEVASGKKPFFDD
. ..||||.| .... .   |.                  . ||....|||.                   .. ....||||||||| |......|..|.
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

Y---TVLG----EWIWELY--RKRSLVE-----AADPALGGVFDGGEMESVLTIGLACSDPSPRNRPTMRQVVNSL
     ...    |...  .  ..| ..            . .     ..|.  .   | |. |..||.. ...  |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LLEC_f-2.AA IRAK 338-540 33 5.9e-55 188.9 In-house 1-227 (317) Show / Hide
Range on Protein: 338-540
Range on HMM: 1-227/317
Sequence Identity: 33% (77 aa)

FDPKNLLGSGGFGNVYAGLLPGDGSPVAVKRIGENSR----QGEREFLA---EVEIITKLSHRNLVHLRGWCCRSRELLLVYEFMPNGSLD---KAIATN
|.. |..|.|||| || | . . . ..|||.. |.      . ...|..   |... ... | |.| | | |  . .. |||..||||||     . .. 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

SS---LDWSKRYEIICGLAAALLYLHEEC-EERIVHRDVKPSNVMLDAGFNARLGDFGLARL-----IDRKREA---RTTAIAGTFGYLAPELNI--TGQ
 .   | | .| .|  |.| .. .||.      | |.|.|..|. ||. |.. ..||||.|         | .    .|  . ||  |..|| .   .||
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

CTTASDVYSFGIVLLEVASGKKPFFDD
 |. .||||||||||||..| ..  ||
LTKKTDVYSFGIVLLEVLTGCRAVYDD

Kinase LLEC_f-2.AA Pkinase 338-540 27 9.5e-47 166.37 Pfam 1-215 (293) Show / Hide
Range on Protein: 338-540
Range on HMM: 1-215/293
Sequence Identity: 27% (61 aa)

FDPKNLLGSGGFGNVYAGLLPGDGSPVAVKRI---GENSRQGEREFL-AEVEIITKLSHRNLVHLRGWCCRSRELLLVYEFMPNG----SLDKAIA--TN
.  .  .|||.|| || .   |.|  ||||.|   .|.| . .. .. .|..|  .|.| | | |..|. ..... .| |....|    .|   |    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SSL--DWSKRYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLDAGFNA----RLGDFGLARLIDRKREARTTAIAGTFGYLAPELNI-TGQCTTASDV
 ..  ..     ..  .. .| |.|..   .|.|||.||.|...|   .     ...|||||...|  .   .| ..|| .|.|||.       ....|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGIVLLEVASGKKPFFDD
.|.|..| |...|. || ..
WSCGCILYEMLCGRPPFPGH

Kinase LLEC_f-2.AA TK 338-602 15 5.8e-46 151.61 In-house 1-486 (486) Show / Hide
Range on Protein: 338-602
Range on HMM: 1-486/486
Sequence Identity: 15% (76 aa)

FDPKNLLGSGGFG---NVYAGLLPGDG-------------------------SPVAVKRIGENSRQGEREFLA--------------EVEIITKLS----
    . ||.| ||    || |.. |..                          ||||| . | . . ..||..              |.|.. ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLVHLRGWCCRSRE------------LLLVYEFMPNGS----LDKAIATNSS---------------------------------------------
 | |.|.| | |.....            ...| |.||.|.    |..   ...                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWSKRYEIICGLAAALLYLHEE---CEERIVHRDVKPSNVMLDAGFN-----------ARLGDFG---
                               |.   .  . . .|... |||.     . ..||||.   |.... . .           ....|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARLIDRKREARTTAIAGTFG-------------------------YLAPELNI---------TGQCTTASDVYSFGIVLLEVAS-GKKPFFDDY
     ||| |... . ...   || .                         ..|||            .| .||.|||.|||... |. . |..|.  . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TVLGEWI-------WELYRKRSL------------VEAADPALGG-------VFDGGEMESVLTI-GLACSDPSPRNRPTMRQVVNSL
.  . |.        |. |. .              . . |..           .  ... .. .  . | .. |. |||..|... |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase LLEC_f-2.AA TKL-Unique 340-537 30 1.8e-43 150.76 In-house 1-234 (290) Show / Hide
Range on Protein: 340-537
Range on HMM: 1-234/290
Sequence Identity: 30% (73 aa)

PKNLLGSGGFGNVYAGLLPGDGSPVAVKRIGENSRQG-E--REFLAEVEIITKLS-HRNLVHLRGWCC----RSRELLLVYEFMPNGSLDKAIA------
. |..|.||.|.|| |   . |.|||.|.. .|. .  |  .||  || .. ||  | |.||. |.|        .. .| |..| |||.. ..      
FWNKIGEGGYGQVYKGK--WRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

----TNSSLDWSKRYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLDAG-----FNARLGDFGLARLIDRKREARTTAI--------AGTFGYLAPEL
     |. |....|. ..   | .. ||| .    | ||| |.||. .| .     .|... ||||... ..  .  .. .         |.| ..|||.
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

NITG---QCTTASDVYSFGIVLLEVASGKK------PF
 ...   | .. |||||||||| | |..|       |.
-LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPY

Kinase LLEC_f-2.AA S_TKc 338-609 22 8.2e-42 146.15 SMART 1-231 (231) Show / Hide
Range on Protein: 338-609
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

FDPKNLLGSGGFGNVYAGLLPGDGSPVAVKRIGENSRQGEREFLAEVEIITKLSHRNLVHLRGWCCRSRELLLVYEFMPN--GSLDKAIATNSS------
..  ...|.|.|| || .   ..|  ||.|.|        . .. |..|  |  | |.|.| ...    .| .| |....  |.| . |  . .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWSKRYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLDAGFNARLGDFGLARLIDRKREARTTAIAGTFGYLAPELNITGQCTT-ASDVYSFGIVLL
..      ... .. || |.|   . .|.|||.||.|..||   .  ..||||||..        | . ||  |.|||.    . .. ..|..|.|..| 
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EVASGKKPFFDDYTVLGEWIWELYRKRSLVEAADPALGGVFDGGEMESVLTIGLACSDPSPRNRPTMRQVVN--SLKGNAPAL
| ..|. ||  .. .. . |                          .... .   | .  |..|||  .. .  ..  . | .
EMLCGYPPFP-QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LLEC_f-2.AA Pkinase_Tyr 338-537 28 2.1e-36 123.9 Pfam 1-216 (270) Show / Hide
Range on Protein: 338-537
Range on HMM: 1-216/270
Sequence Identity: 28% (64 aa)

FDPKNLLGSGGFGNVYAGLLP----GDGSPVAVKRIGENSRQGE---REFLAEVEIITKL-SHRNLVHLRGWCC-RSRE--LLLVYEFMPNGSLDKAIAT
      ||.| ||.|| | .     ... ||||| . |.. . .   ..|..|..| ..| .| |.| | | |  ...   ...| |.||.|.|..   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----NSSLDWSKRYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLDAGFNARLGDFGLARLI-----D-RKREARTTAIAGTFGYLAPELNITGQCTT
    . .|. .   ..    |... ||..     ..|||.   |.... .. .. .||||||.|       |||.     |  .    |||   .| .||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFTT

ASDVYSFGIVLLEVAS-GKKP-F
.|||.|||... |. . |..| .
KSDVWSFGVLMWEIFTYGEQPTY

Kinase LLEC_f-2.AA LISK 343-536 26 4e-34 108.12 In-house 1-238 (296) Show / Hide
Range on Protein: 343-536
Range on HMM: 1-238/296
Sequence Identity: 26% (65 aa)

LLGSGGFGNVYAGLLPGDGSPVAVKRIGE-----NSRQGEREFLAEVEIITKLSHRNLVHLRGWCCR-SRELLLVYEFMPNGSLDKAIA-TNS---SLDW
 .|.|.|| || | .  .|...|.| | .     | .  .. .| ||... .|.|.| |.  | |.. ...| .| |..  | |   .. ...    | |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

SKRYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLD----AGFNARLGDFGLARLIDRKREA---------------------------------RTT
..|  |  . | .. |||. .   |.||| |  |. ..     .......|||.||..| ..                                   |. 
PQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

AIAGTFGYLAPELNITGQC-TTASDVYSFGIVLLEVASGKKP
.| ||    |||  ..||  ....||.||||||.|   ..|.
TICGTPYWMAPEM-LLGQSYDESCDVFSFGIVLCEIITRVKA

Kinase LLEC_f-2.AA MLK 338-537 23 1.8e-33 113.5 In-house 1-236 (291) Show / Hide
Range on Protein: 338-537
Range on HMM: 1-236/291
Sequence Identity: 23% (57 aa)

FDPKNLLGSGGFGNVYAGLLPGDGSP-----VAVKRIG----ENSRQG--EREFLAEVEIITKLSHRN----LVHLRGWCCRS-RELLLVYEFMPNGSLD
.. .  .|||.|| |. |     .       |||||.     . |. .   ..|  |...  .|||.|     . ..| | ..  ....| |....||| 
IQFHEWIGSGSFGKVWKGRW--RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

KAIATNSS--------------LDWSKRYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLDA------GFNARLGDFGLARLIDRKREARTTAIAGTF
  .....|               | .    .    | .. |||..    |.||| |..|...|.      . ...  |||..| . ..  .  .  |||.
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTY

GYLAPEL---NITGQCTTASDVYSFGIVLLEVASGKKPF
 . |||       .... ..||.|.|.|| |. ... |.
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPY

Kinase LLEC_f-2.AA Dicty4-Unclassified 341-537 30 3.3e-33 111.08 In-house 4-208 (263) Show / Hide
Range on Protein: 341-537
Range on HMM: 4-208/263
Sequence Identity: 30% (65 aa)

KNLLGSGGFGNVYAGLLPGDGSPVAVKRIGENSRQGE----REFLAEVEIITKLSHRNLVHLRGWCCRS----RELLLVYEFMPNGSLDKAIA-----TN
   .| | |  |. |     |  |||| . ||. .       .|..||||   ..| ||| ..| |         .  | |||. | |   |       .
DQFIGKGHFSKVHKGNW--KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

SSLDWSK--RYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLDAGFNARLGDFGLARLIDRKREARTTAIAGTFGYLAPELNITGQCTTASDVYSFGI
 ..         .    |  . .||      ..|||.| ||...|  ||.. .|||..| ||       |.||||    .||       . .|||||...
QPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNM--TTIAGTPKWESPECLMHESYNQKSDVYSYAM

VLLEVASGKKPF
.| | | |  |.
MLYELATGDEPY

Kinase LLEC_f-2.AA TyrKc 338-602 23 5.8e-33 116.76 SMART 1-280 (280) Show / Hide
Range on Protein: 338-602
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FDPKNLLGSGGFGNVYAGLLPGDGSPVAVKRIGENSRQGEREFLAEVEIITKL--SHRNLVHLRGWCCRS-------RELLLVYEFMPNGSLDKAIATNS
   .  ||.| || || | .     .|||| . |..   ...|. | .| .||  .| |.| | | |  .         |..| |.||.|.|.. .  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

S-LDWSKRYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLDAGFNARLGDFGLARLIDRK-------REART----TAIA-GTFGYLAPELNITGQCT
  | ...  ..    |.   |||.    ...|||    |....... .. .||||.| |. .          |.     . .      .|||   .| .|
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

TASDVYSFGIVLLEVAS-GKKPFFDDYT--VLGEWIWELYRKRSLVEAADPALGGVFDGGEM------ESVLTIGLACSDPSPRNRPTMRQVVNSL
|.|||.|||... |. . |..|  ..    .  . . |. ...   .  . ..       .|      . . .| . | .  | .|||.....  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-------PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase LLEC_f-2.AA STE 338-541 21 8.3e-32 109.64 In-house 1-272 (359) Show / Hide
Range on Protein: 338-541
Range on HMM: 1-272/359
Sequence Identity: 21% (62 aa)

FDPKNLLGSGGFGNVYAG-------LLPGDGSP---------VAVKRIG-----------ENSRQG--------EREFLAEVEIITKLS--HRNLVHLRG
..    .|.|.|| || .       .    |           .|.|..            || .          . ..| |..|  |..  | | |.  |
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG

WCCRSR-------ELLLVYEFMPNGSLDKAIA----TNSSLD----------WSKRYEIICGLAAA-LLYLHEECEERIVHRDVKPSNVMLDAGFNARLG
 . .         || .. |.|..||||. |     .. .|.           |    |.. .  . | |||.     |.|||.||.|..|     . | 
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLC

DFGLARLIDRK--------------REA-RTTAIAGTFGYLAPELNIT------GQCTTASDVYSFGIVLLEVASGKKPFFDDY
|||..  .. .                . ... ..||  . |||          ....| .|..|.|....| | || |..| .
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMH

Kinase LLEC_f-2.AA Dicty4 338-538 28 1.1e-29 96.37 In-house 1-218 (277) Show / Hide
Range on Protein: 338-538
Range on HMM: 1-218/277
Sequence Identity: 28% (63 aa)

FDPKNLLGSGGFGNVYAGLLPGDGSPVAVKRI---GENSRQGE-REFLAEVEIITKLSHRNLVHLRGWCC----RSRELLLVYEFMPNGSLDKAIAT---
 .  ...|.|.|| || |     |. ||||      .|... .  ||..||.|  |..| |.. . | |      . ... | |.|| |.| . .     
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

----NSSLDWSKRYE-IICGLAAAL--LYLHE-ECEERIVHRDVKPSNVMLDAGFNARLGDFGLARLIDRKREART--TAIAGTFGYLAPELNITGQCTT
    . .|||. .   .  .. ||.   .||.  .  .|.||| |..| . |. ...  .||||.... .  .  .  .. .|| .. |||       . 
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNP--VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

ASDVYSFGIVLLEVASGKKPFF
..||||||||| | . .. |..
KADVYSFGIVLWEILTRQEPYQ

Kinase LLEC_f-2.AA TK-Unique 338-532 24 1.8e-28 95.34 In-house 1-234 (294) Show / Hide
Range on Protein: 338-532
Range on HMM: 1-234/294
Sequence Identity: 24% (58 aa)

FDPKNLLGSGGFGNVYAGLLPGDG------SPVAVKRIGENSRQGE-REFLAEVEIITKLS-HRNLVHLRGWCCRSR-ELLLVYEFMPNGSLDKAIATNS
.  ....|.| || |. | . |.       . ||||   .|... . ..|| | ..  .|  | |.|.. | |..|    ....|..|.|.|.. . |. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

S--------------------------LDWSKRYEIICGLAAALLYLHEECEERIVHRDVKPSNVMLDAGFNARLGDFGLAR------LIDRKREARTTA
                           ..    | .....| .. ||..   ..|||||.  .||.|  .... ..|||.||       ......  .. 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLAS-QRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

IAGTFGYLAPELNI--TGQC-TTASDVYSFGIVLLEVAS
|.    ..|||     .|.. || |||.|||... |...
IR----WMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT

Kinase LLEC_f-2.AA MLK 586-602 41 0.000953 9.03 In-house 275-291 (291) Show / Hide
Range on Protein: 586-602
Range on HMM: 275-291/291
Sequence Identity: 41% (7 aa)

DPSPRNRPTMRQVVNSL
.. |..||..||.|  |
NQDPHKRPSFRQIVQHL

Kinase LLEC_f-2.AA Dicty4-Unclassified 584-602 42 0.001103 8.45 In-house 245-263 (263) Show / Hide
Range on Protein: 584-602
Range on HMM: 245-263/263
Sequence Identity: 42% (8 aa)

CSDPSPRNRPTMRQVVNSL
|   .|. |||| |... |
CWHNDPNKRPTMNQIIQYL

Kinase LLEC_f-2.AA Dicty4 584-604 26 0.006237 5.81 In-house 255-277 (277) Show / Hide
Range on Protein: 584-604
Range on HMM: 255-277/277
Sequence Identity: 26% (6 aa)

CSDPSPRNRPTMRQVVNS--LKG
| |..| .||.. ....   |  
CWDHDPQHRPSFEEIIQRRILEH

Kinase LLEC_f-2.AA IRAK 590-602 30 0.041481 3.47 In-house 305-317 (317) Show / Hide
Range on Protein: 590-602
Range on HMM: 305-317/317
Sequence Identity: 30% (4 aa)

RNRPTMRQVVNSL
..|..|..|...|
NRRCDMAWVMQQL

Kinase LLEC_f-2.AA TKL-Unique 583-602 25 0.125841 1.73 In-house 271-290 (290) Show / Hide
Range on Protein: 583-602
Range on HMM: 271-290/290
Sequence Identity: 25% (5 aa)

ACSDPSPRNRPTMRQVVNSL
.| .. | .||.  .....|
QCWHHDPSQRPSFDEIIHRL

Kinase LLEC_f-2.AA Pkinase_Tyr 586-602 29 0.326539 4.73 Pfam 254-270 (270) Show / Hide
Range on Protein: 586-602
Range on HMM: 254-270/270
Sequence Identity: 29% (5 aa)

DPSPRNRPTMRQVVNSL
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HYDPEDRPTFSEIHEQL