Gene LLEC_a-1 (S.moellendorffii)

LLEC_a-1

Species: S.moellendorffii
Alias: LLEC_a-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LLEC

Sequence

Name Sequence Type Origin Length Description Download
LLEC_a-1.AA Protein None 1335 None Fasta, JSON
LLEC_a-1.NA RNA None 4008 None Fasta, JSON
LLEC_a-1.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of LLEC_a-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Lectin_legB LLEC_a-1.AA Lectin_legB 42-281 32 1e-60 212.83 Pfam 1-268 (268) Show / Hide 
Range on Protein: 42-281
Range on HMM: 1-268/268
Sequence Identity: 32% (88 aa)

TLVSFTFDPPF-TNN----RYLNVEGNAS-KTTEDVELT-TNSV--DVVIGNSAGRAYYVDPIQFLDPDDSSTC--VSFSSIFTFKLVQFNNSSYRPGDG
. |||.. . |  |.    . |.  |.|.  ..   .|| ...    ....||.|.| |  ||.|. . ||||    |||  |.|   . .... ..|.|
ETVSFNY-NGFTSNQCPSWSNLTLQGDATVHPNGALQLTPNVTNNPPPQPTNSMGHAFYPKPIHFWEDWDSSTGKVASFSTSFVFAIYNIPSYNTNGGHG

MAFMIVSDP-QLPLNS-AGAYLGLTNASLDG-DSRNHFLAVEFDTFQDSSAG--DPAR-DHIGVNINGIRSVDVFKLE------GELTNLLRSN--STLT
||| |.... | | .. .| ||||.| . .| .. |||.||||||||..  .  |.   .|.|...|.||||.. ..       |  .|.  ..  .. .
MAFFIAPSDTQNPPGASSGQYLGLFNPTNNGDNPSNHFVAVEFDTFQNPEFNDWDD-NYNHVGIDVNSIRSVKSEPAGYYDDDDGRFVNWDLNSYGKPMQ

AWVEYESSQQLLEIRVSTL--S--QRPRLPLLKYQVELAGIVQEKMYVGFSAAT-SLNYELHKILTWKFS
.|..| .|  .|   .. .  .   .|. ||| ..|.| ... ..|||||||.|  . .|.| || | ||
VWIDYDGSSKQLNVTLAYPWTNMAFKPKRPLLSWSVDLSQVLPDWMYVGFSASTGGNYTESHYILSWSFS
Kinase LLEC_a-1.AA TKL 377-642 21 8.3e-65 221.62 In-house 1-364 (364) Show / Hide 
Range on Protein: 377-642
Range on HMM: 1-364/364
Sequence Identity: 21% (83 aa)

IGSGGFGKVYKGILPK--------DGTLVAVKLLSEASLQSE---------------------------RQFLAELSVIGRLQHRNLVSLKG--------
|||||||.||||..          .|. |||| ... . ...                            ..  |. .. ||.| |.|...|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-WCHD----KGKLLLVYEFMPNGS-LDKHLFSADITLLWQQRFHILKGVGEALTFLHDGW-----EQRVIHRDVKAANVLLDSKFT--------------
 .|..    .|.| .|.|..|.|| |. ..        |.||... ...  .. .||  .        .|||| | .|.|.|...|              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

ARLGDFGLARLMEHS------------------RGPQTMTKAGTTGYIAPELA-----YT-----------GRATEKSDVYSFGILALEVVSGRRALDLD
. ..||||.| |..|                  .. .|||. ||... |||.      ||           . ..||.|||||||.  |.....|     
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----

FEFDKEGVLLLDWIWQ-MHERGRL---------MEVVDAKLQDDFD------------VEQVTVVLYMALQCCHPDANDRPTMRKCCQML
              .. .... ..         | |.| .|.   .                . .   . .|...|...||.. .. . |
-------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LLEC_a-1.AA IRAK 371-572 37 1.2e-58 201.14 In-house 1-226 (317) Show / Hide 
Range on Protein: 371-572
Range on HMM: 1-226/317
Sequence Identity: 37% (85 aa)

FSRKEMIGSGGFGKVYKGILPKDGTLVAVK-LLSEASLQ---SERQFLA---ELSVIGRLQHRNLVSLKGWCHDKGKLLLVYEFMPNGSLDKHLFSADI-
|..   ||.|||| ||.| .   .  .||| | ..|...   ....|..   || |  |..| |.|.| | | . ... |||..||||||   |   |  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-T---LLWQQRFHILKGVGEALTFLHDGW-EQRVIHRDVKAANVLLDSKFTARLGDFGLAR------LMEHSRG--PQTMTKAGTTGYIAPELAY--TGR
 .   | |.||. |. | . .. |||.      .||.|.| ||.|||  ||. ..||||.|       .|..      | .  ||| | .||  .  .|.
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ATEKSDVYSFGILALEVVSGR-RALD
 | |.|||||||  |||..|. ...|
LTKKTDVYSFGIVLLEVLTGCRAVYD
Kinase LLEC_a-1.AA Pkinase 371-642 21 4.7e-52 184.04 Pfam 1-293 (293) Show / Hide 
Range on Protein: 371-642
Range on HMM: 1-293/293
Sequence Identity: 21% (68 aa)

FSRKEMIGSGGFGKVYKGILPKDGTLVAVKLLSEASLQS--ERQFLA--ELSVIGRLQHRNLVSLKGWCHDKGKLLLVYEFMPNG----SLDKHLF-SAD
. ... ||||.||.|||..  ..| .|||| ..  .  |  ... .   |...  ||.| | | |..|..||... .| |....|    .|  ..  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ITL--LWQQRFHILKGVGEALTFLHDGWEQRVIHRDVKAANVLLDSKFTA----RLGDFGLARLMEHSRGPQTMTKAGTTGYIAPELAY-TGRATEKSDV
 ..   ...  .... . ..| ..|.    ..||||.| .|.|.|.. .     ...|||||..... ... ..| .|| .|.|||.       . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGILALEVVSGRRALDLDFEFDKEGVLLLDWIWQMH----ERGRLMEVVDAKLQ--DDFDVEQV---------------------TVVLYMALQCCHP
.|.|..  |...||                   ... |    .  . |.... ...   .|| ..                         .     |...
WSCGCILYEMLCGR------------------PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

DANDRPTMRKCCQM--L
| ..||| . ..|   .
DPKKRPTAEQILQHPWF
Kinase LLEC_a-1.AA TK 371-566 16 1.5e-44 146.76 In-house 1-389 (486) Show / Hide 
Range on Protein: 371-566
Range on HMM: 1-389/486
Sequence Identity: 16% (64 aa)

FSRKEMIGSGGFG---KVYKGILPKDG-------------------------TLVAVKLLSEASLQSERQFLA--------------ELSVIGRLQ----
    . .|.| ||   .||||..  ..                         | |||| | | . .|...|..              |....  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLVSLKGWCHDK------------GKLLLVYEFMPNGS----LDKHLFSADIT--------------------------------------------
 | |.|.| | |...            . ...| |.||.|.    |...| . . .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LLWQQRFHILKGVGEALTFLHDG---WEQRVIHRDVKAANVLLDSKFT-----------ARLGDFG---
                               |  .|.  .   . ... .||.     .|...|||. | |.|.... .           ....|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARLMEHSRGPQTMTKAGTTG-------------------------YIAPELAY---------TGRATEKSDVYSFGILALEVVS
     ||| ....    ...  ||..                         . |||            .|. |.||||.|||.|  |...
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase LLEC_a-1.AA S_TKc 371-642 21 4.5e-43 150.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 371-642
Range on HMM: 1-231/231
Sequence Identity: 21% (63 aa)

FSRKEMIGSGGFGKVYKGILPKDGTLVAVKLLSEASLQSERQFLAELSVIGRLQHRNLVSLKGWCHDKGKLLLVYEFMPN--GSLDKHLFSAD-------
.   . ||.|.||||||..  |.| .||.| ..       .... |...  . .| |.| |.....| ..| .| |....  |.| ... .         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

ITLLWQQRFHILKGVGEALTFLHDGWEQRVIHRDVKAANVLLDSKFTARLGDFGLARLMEHSRGPQTMTKAGTTGYIAPELAYTGRATE-KSDVYSFGIL
..  . .  .... . .|| ..|   ....||||.| .|.|||.  .  ..||||||..        .|  ||  |.|||.      .  |.|..|.|..
FPE-HAR--FYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

ALEVVSGRRALDLDFEFDKEGVLLLDWIWQMHERGRLMEVVDAKLQDDFDVEQVTVVLYMALQCCHPDANDRPTMRKCCQ---------ML
  | ..|.   .       .  .... |                            .. .  .|.. | ..|||  .. |          .
LYEMLCGYPPFP-------QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LLEC_a-1.AA Pkinase_Tyr 371-560 28 1e-42 145.27 Pfam 1-203 (270) Show / Hide 
Range on Protein: 371-560
Range on HMM: 1-203/270
Sequence Identity: 28% (59 aa)

FSRKEMIGSGGFGKVYKGILP----KDGTLVAVKLLSEASLQSE---RQFLAELSVIGRL-QHRNLVSLKGWCH-DKGK--LLLVYEFMPNGSLDKHLFS
 .  ...|.| ||.||||..     .... |||| | | . ...   . |..|...   | .| |.|.| | |  ...   ...| |.||.|.|...| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

A---DITLLWQQRFHILKGVGEALTFLHDGWEQRVIHRDVKAANVLLDSKFTARLGDFGLARLMEHSRGPQTMTKAGTTGYI-----APELAYTGRATEK
    .  |  ..  ..   . ... .|.   ... ||||. | |.|........ .||||||..      .  ..... | .     |||   .|. |.|
HREDKQPLTMKDLLQMCWQIAKGMEYLE---SKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTK

SDVYSFGIL
|||.|||.|
SDVWSFGVL
Kinase LLEC_a-1.AA TyrKc 371-642 24 4e-40 140.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 371-642
Range on HMM: 1-280/280
Sequence Identity: 24% (74 aa)

FSRKEMIGSGGFGKVYKGILPKDGTLVAVKLLSEASLQSERQFLAELSVIGRL--QHRNLVSLKGWCHDK-------GKLLLVYEFMPNGSLDKHLFSAD
 . ....|.| ||.||||..    . |||| | | .   .. |. |...  .|  .| |.| | | | ..       . |..| |.||.|.|...| .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

ITLLWQQRFHILKGVGEALTFLHDGWEQRVIHRDVKAANVLLDSKFTARLGDFGLARLMEHS-----RGPQTMTKA--GTTG-----YIAPELAYTGRAT
 .| ...  ..   . .   .||.    ..||||  | |.|.....|.. .||||.|  ..      ..   ..|   |. .       |||   .|. |
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKSDVYSFGILALEVVSGRRALDLDFEFDKEGVLLLDWIWQMHERGRLMEVVDA----KLQDDFDVEQVTVVLYMALQCCHPDANDRPTMRKCCQML
.||||.|||..  |. .       . ..    ..  . . .  ..|. |.  .          | |.  . .  . .||.| |..||||.. ... .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMS----F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LLEC_a-1.AA LISK 376-570 26 9e-39 123.47 In-house 1-238 (296) Show / Hide 
Range on Protein: 376-570
Range on HMM: 1-238/296
Sequence Identity: 26% (65 aa)

MIGSGGFGKVYKGILPKDGTLVAVKLLSE-----ASLQSERQFLAELSVIGRLQHRNLVSLKGWCHD-KGKLLLVYEFMPNGSLDKHLFS---ADITLLW
 ||.|.||||||| .  .|. .|.| ...          .. .| |. .. .|.|.| |   | |   .|.| .| |..  | |   |..    .| | |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

QQRFHILKGVGEALTFLHDGWEQRVIHRDVKAANVLLDSK----FTARLGDFGLARLMEHSRGP---------------------------------QTM
.|| .| ... .....||   .. .|||| |. |.|.. .    ......|||.||.|. ....                                 ..|
PQRVKIALDIACGMSYLH---SMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

TKAGTTGYIAPELAYTGRATEKSDVYSFGILALEVVSGRRA
|  ||.   |||       .|..||.||||. .| . ...|
TICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA
Kinase LLEC_a-1.AA STE 371-568 22 9.8e-38 130.85 In-house 1-265 (359) Show / Hide 
Range on Protein: 371-568
Range on HMM: 1-265/359
Sequence Identity: 22% (61 aa)

FSRKEMIGSGGFGKVYKGILPK---------------DGTLVAVKLLSEASL-----------------QSERQFLAELSVIGRLQ--HRNLVSLKGWCH
. . |.||.|.||.|||..  |                |...|.| ..  .                  . . |.| |...  ...  | | |   | . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DKG-------KLLLVYEFMPNGSLD---KHLFSADITLL----------WQQRFHILKGVGEA-LTFLHDGWEQRVIHRDVKAANVLLDSKFTARLGDFG
..|       .| .. |.|..||||   || ..   .|            .|  .|.. . .. | .||   ....||||.|.||.||     . | |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLH---SHHIIHRDIKPANILL-----VKLCDFG

LARLMEH---------------SRGPQTMTKAGTTGYIAPELAYTGR------ATEKSDVYSFGILALEVVSGR
..  ...               ... .. | .||  . |||    ..       ..|.|..|.|....| . |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LLEC_a-1.AA TKL-Unique 375-559 26 1.4e-34 119.43 In-house 3-216 (290) Show / Hide 
Range on Protein: 375-559
Range on HMM: 3-216/290
Sequence Identity: 26% (58 aa)

EMIGSGGFGKVYKGILPKDGTLVAVKL-LSEASLQSERQFLAELSVIGRLQ-HRNLVSLKGWCH----DKGKLLLVYEFMPNGSLDKHLF---------S
. ||.||.|.||||. ... . . ..  ... |..... |  |.... .|. | |.| . |.|.    . ... .| |..| |||...|          .
NKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

ADITLLWQQRFHILKGVGEALTFLHDGWEQRVIHRDVKAANVLLDSK-----FTARLGDFGLARLMEHS-RGPQTM-------TKAGTTGYIAPELAYT-
  ..| .||| .. . .  .. .||      .|||| |  |.|.|..     . ... ||||...   . ... ..       |. |.. ..|||.    
NNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMN

-GRATEKSDVYSFGI
    .||||||||||
FCQYSEKSDVYSFGI
Kinase LLEC_a-1.AA RIPK 377-570 26 4.6e-34 113.46 In-house 1-227 (290) Show / Hide 
Range on Protein: 377-570
Range on HMM: 1-227/290
Sequence Identity: 26% (60 aa)

IGSGGFGKVYKGILPKDGTLVAVKL---LS-EASLQS--ERQFLAELSVIGRLQHRNLVSLKGWCHDK-----GK-LLLVYEFMPNGSLDKHLFSAD---
.|.||||.|.|    . |. ||.|    .  .. ...  . . . |     .|.... |...| | ..     .| . .| |.|.|||| . | .     
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-ITLLWQQRFHILKGVGEALTFLHDGWEQR--VIHRDVKAANVLLDSKFTARLGDFGLARLMEHS------------RGPQTMTKAGTTGYIAPELAY--
   ..|  |. ... . ..  .||.   .   .|||| | .|.|.|. | . . |||||  |. |            .. .   . ||  |..||.    
HHPDPWPLRCRMIHEISCGMCYLHS---MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTD

-TGR---ATEKSDVYSFGILALEVVSGRRA
   .   .|.|.|||||.|.  || ... .
NKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LLEC_a-1.AA MLK 371-560 24 2.3e-33 113.13 In-house 1-225 (291) Show / Hide 
Range on Protein: 371-560
Range on HMM: 1-225/291
Sequence Identity: 24% (57 aa)

FSRKEMIGSGGFGKVYKGILPKDGTL-----VAVKLLS---EASLQSE----RQFLAELSVIGRLQHRN----LVSLKGWCHDKGK-LLLVYEFMPNGSL
.  .| ||||.||||.||     ...     ||||      . . ...    ..|  |     .|.|.|     . ..| |.. .. ...| |....|||
IQFHEWIGSGSFGKVWKGRW--RNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSL

DKHLFSAD-------------ITLLWQQRFHILKGVGEALTFLHDGWEQRVIHRDVKAANVLLDS------KFTARLGDFGLARLMEHSRGPQTMTK-AG
   | .|.             ..   .. . . . . ... .||    . .|||| |  |.|.|       . |..  |||..| . ..   ..|.. ||
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAG

TTGYIAPEL---AYTGRATEKSDVYSFGIL
|  . |||    .  .. .||.||.|.|..
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVV
Kinase LLEC_a-1.AA LRRK 371-572 22 4.8e-33 114.24 In-house 1-284 (351) Show / Hide 
Range on Protein: 371-572
Range on HMM: 1-284/351
Sequence Identity: 22% (65 aa)

FSRKEMIGSGGFG-KVYKGILPKD--------------------------GTLVAVKLLSEA----------------------------------SLQS
. . |.||.|||| .||.... .                           .. ||.| .                                     .. .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

ERQFLAELSVIGRLQHRNLVSLKGWCHDKGKLLLVYEFMPNGSLDKHLF---SAD-----ITLLWQQRFHILKGVGEALTFLHDGWEQR--VIHRDVKAA
 | |  |.... .|.| |.||||| |..   | .| |..|.|.|...|.   .       . . |. .  |   . ... .||.   ..  .|||| |  
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS---HNPPIIHRDLKSP

NVLL-DSK-----------FTARLGDFGLARLMEHSRGPQ-TMTKAGTTGYIAPELAYTG---RATEKSDVYSFGILALEVVSGR-RALD
|.||  |.            .| ..|||. | |  . ..  .... |. |. |||    .     |||.|.||||..  | .... .. |
NILLWSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase LLEC_a-1.AA Dicty4 490-560 39 4.6e-20 63.76 In-house 134-206 (277) Show / Hide 
Range on Protein: 490-560
Range on HMM: 134-206/277
Sequence Identity: 39% (29 aa)

RVIHRDVKAANVLLDSKFTARLGDFGLAR-LMEHSRGPQ-TMTKAGTTGYIAPELAYTGRATEKSDVYSFGIL
..|||| |..| | |  ...  .||||..   .|.   . .|| .||... |||     . .||.|||||||.
VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIV
Kinase LLEC_a-1.AA Dicty4 371-453 32 4.6e-13 40.09 In-house 1-89 (277) Show / Hide 
Range on Protein: 371-453
Range on HMM: 1-89/277
Sequence Identity: 32% (31 aa)

FSRKEMIGSGGFGKVYKGILPKDGTLVAVKLL-------SEASLQSERQFLAELSVIGRLQHRNLVSLKGWCH----DKGKLLLVYEFMPNGSL
  . . ||.|.||.||||.    |. ||||.|       .|. |..   |..| .  . ..| |.. ..| |      .||.. | |.|| |.|
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNE---FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNL
Kinase LLEC_a-1.AA TK 617-642 37 8e-06 14.67 In-house 460-486 (486) Show / Hide 
Range on Protein: 617-642
Range on HMM: 460-486/486
Sequence Identity: 37% (10 aa)

VLYM-ALQCCHPDANDRPTMRKCCQML
..|   .||.|.|..||||.. . ..|
EYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LLEC_a-1.AA Pkinase_Tyr 622-642 42 0.000187 15.71 Pfam 250-270 (270) Show / Hide 
Range on Protein: 622-642
Range on HMM: 250-270/270
Sequence Identity: 42% (9 aa)

LQCCHPDANDRPTMRKCCQML
.|| |.|..||||.. . ..|
KQCWHYDPEDRPTFSEIHEQL
Kinase LLEC_a-1.AA MLK 623-642 40 0.008112 5.76 In-house 272-291 (291) Show / Hide 
Range on Protein: 623-642
Range on HMM: 272-291/291
Sequence Identity: 40% (8 aa)

QCCHPDANDRPTMRKCCQML
|| ..|...||..| . | |
QCWNQDPHKRPSFRQIVQHL
Kinase LLEC_a-1.AA IRAK 621-642 40 0.041748 3.46 In-house 296-317 (317) Show / Hide 
Range on Protein: 621-642
Range on HMM: 296-317/317
Sequence Identity: 40% (9 aa)

ALQCCHPDANDRPTMRKCCQML
|..| |  || |..|..  | |
ACCCGHHRANRRCDMAWVMQQL
Lectin_legB LLEC_a-1.AA Lectin_legB 711-953 32 2.5e-50 178.33 Pfam 1-268 (268) Show / Hide 
Range on Protein: 711-953
Range on HMM: 1-268/268
Sequence Identity: 32% (90 aa)

EAISFDLRPSF-KQS----QALLIQGQARA-TNESLELTGAFDSSI-------INAGRVFYALPIRFVHQSGK-NIRISSFNTVFEFQVNSALDRSNCKQ
|..||   ..| . .    . |. || |.  .|  |.||   ...          .|..||. ||.| .   . . . .|| | | | . .  . .|.  
ETVSFNY-NGFTSNQCPSWSNLTLQGDATVHPNGALQLT--PNVTNNPPPQPTNSMGHAFYPKPIHFWEDWDSSTGKVASFSTSFVFAIYNIPS-YNTNG

GDGFAFVAAASASS-PPNGSDAGYLGLMNSSTAG-NASNHLFAVEFDSVQNVEFA--DPPWSHVGVNVNSMISLET----------ARWERPSFPPFKTA
|.|.||. | | .  ||..|...|||| |....| |.||| .||||| .||.||   |..  |||..|||..|  .                .|.... .
GHGMAFFIAPSDTQNPPGASSGQYLGLFNPTNNGDNPSNHFVAVEFDTFQNPEFNDWDDNYNHVGIDVNSIRSVKSEPAGYYDDDDG-----RFVNWDLN

N----SKAWIDYDASTDVLQVRVSNE--N-IGVKPANALLAVSGLQLSEVFHRSMFIGFSASS-GSCNDSHEIMRWQFD
.     ..|||||.|. .|.| ..    |    ||  .||  |   ||.|.. .|..|||||. |.   ||.|  | | 
SYGKPMQVWIDYDGSSKQLNVTLAYPWTNMA-FKPKRPLLSWSV-DLSQVLPDWMYVGFSASTGGNYTESHYILSWSFS
Kinase LLEC_a-1.AA TKL 1041-1303 21 1.9e-68 233.72 In-house 1-364 (364) Show / Hide 
Range on Protein: 1041-1303
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

LGRGAFGTVYKAEFKGPT---------TVAVKILAQTGLEVE---------------------------HQFLAELSTLGKIKHPNLVDLQG--------
.|.|.||.|||....| .         .||||.. ..    .                            ..  |.  . ...|||.| . |        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-WCHS----RGKLMLVYEYLPNGS-LDRHLFSESEKFLSWERRSQIIHGVAEAIKFLHQ-----GHEE-CILHRDIKAANVLLDKNFK------------
 .|..     |.|..|.|| |.|| |....         |..| ......| .. .||.     .     |.|||.| .|.|.|.|..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AKLGDFGLARLFDHTD----------------QGVLQTMTRVGTAGYIAPELAF----------------AGKATEKSDVYSFGVLILEIVTGRRTIS
  .|..||||.| ....                 ..  .|||..|| .. |||.                   ....||.||||||... ||.|..|   
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

LACSKTLIDRVWGMQES------NALLEIVDERMRSSYN------------PDEARMLLHLGLTCCSMDADERPTMGECCKIL
        .  . |..         .  ..|...|                ||  . .  |   |...|...||.. |. |.|
------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LLEC_a-1.AA IRAK 1035-1235 37 5.3e-63 215.63 In-house 1-222 (317) Show / Hide 
Range on Protein: 1035-1235
Range on HMM: 1-222/317
Sequence Identity: 37% (84 aa)

FDERLVLGRGAFGTVYKAEFKGPT-TVAVK-ILAQTGLE---VEHQFLA---ELSTLGKIKHPNLVDLQGWCHSRGKLMLVYEYLPNGSLDRHLFSES-E
|.. ...| |.||.||....|. | ..||| . .   ..   .. .|..   || .. .. |||.|.| | |  |... |||.|.|||||   |      
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

KF---LSWERRSQIIHGVAEAIKFLHQGH-EECILHRDIKAANVLLDKNFKAKLGDFGLARLF---DHTDQGVL---QTMTRVGTAGYIAPELAF--AGK
     ||| .|  |  | | .| |||| |    | |.||| ||.|||..| .|..||||.|      |  ....    | . .||. | .||      |.
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ATEKSDVYSFGVLILEIVTGRR
 | |.||||||. .||..||.|
LTKKTDVYSFGIVLLEVLTGCR
Kinase LLEC_a-1.AA S_TKc 1035-1302 23 1.4e-47 165.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 1035-1302
Range on HMM: 1-231/231
Sequence Identity: 23% (66 aa)

FDERLVLGRGAFGTVYKAEFKG-PTTVAVKILAQTGLEVEHQFLAELSTLGKIKHPNLVDLQGWCHSRGKLMLVYEYLPN--GSLDRHLFSESEKF----
..   ..|.||||.|||.  |.    ||.||.         ... |.. | | .|||.| | ..... ..| .| ||...  |.| ... .   .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSWERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANVLLDKNFKAKLGDFGLARLFDHTDQGVLQTMTRVGTAGYIAPELAFAGKATE-KSDVYSFGVL
..  .   ... ...|....   |.  |.|||.| .|.|||.    |..||||||..          .| .||  |.|||.    . .  |.|..|.|..
FPE-HARFYMYQICCALEYC---HSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

ILEIVTGRRTISLACSKTLIDRVWGMQESNALLEIVDERMRSSYNPDEARMLLHLGLTCCSMDADERPTMGECCK----------I
. | ..|.   .    .......                      ..||. ..     |. .| ..|||  |. .          .
LYEMLCGYPPFP--QMQMMFKKIG---------------------SPEAKDFIRK---CLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LLEC_a-1.AA Pkinase 1035-1303 21 7.9e-46 163.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1035-1303
Range on HMM: 1-293/293
Sequence Identity: 21% (66 aa)

FDERLVLGRGAFGTVYKAEFKGPTT-VAVKILAQTGLEV---EHQFL-AELSTLGKIKHPNLVDLQGWCHSRGKLMLVYEYLPNG----SLDRHLFSESE
.    ..|.|.||.|||.  ||    |||||.   . .    .. .. .|.. . ...||| | | .|....... .| ||...|    .| ...  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KFL--SWERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANVLLDKNFKA----KLGDFGLARLFDHTDQGVLQTMTRVGTAGYIAPELAF-AGKATEKS
. .  |..    ..  ........|. .   |.|||.| .|.|.|.|       |..|||||..||        ..|..|| .|.|||.   . . . |.
GCFYFSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGVLILEIVTGRRTISLACSKTLIDRVWGMQ----ESNALLEIVDERMRSSYNPDEA-----------------------RMLLHLGLTCCSMDAD
|..|.|... | ..||               .  .    . .  .......|.  .  |.                        . ....   |. .|  
DMWSCGCILYEMLCGR-------------PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK

ERPTMGECCKI--L
.|||  ....   .
KRPTAEQILQHPWF
Kinase LLEC_a-1.AA Pkinase_Tyr 1035-1232 32 8.5e-46 155.73 Pfam 1-209 (270) Show / Hide 
Range on Protein: 1035-1232
Range on HMM: 1-209/270
Sequence Identity: 32% (69 aa)

FDERLVLGRGAFGTVYKAEFK-----GPTTVAVKIL-AQTGLEV--EHQFLAELSTLGKI-KHPNLVDLQGWCH-SRGK--LMLVYEYLPNGSLDRHLFS
     .||.||||.|||.. |     . ..||||.|  ..  |      |..|.... .. .|||.| | | |   ..   ...| || |.|.|. .| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

E--SEKFLSWERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANVLLDKNFKAKLGDFGLARLFDHTDQG-VLQTMTRVGTAGYIAPELAFAGKATEKSD
   ... |. ..  |. . .|..  .|.. .   . |||. | |.|...|...| .||||||.  ..|.  . .. ...    . |||  . || |.|||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGKFTTKSD

VYSFGVLILEIVT
|.|||||. ||.|
VWSFGVLMWEIFT
Kinase LLEC_a-1.AA TK 1035-1232 18 1.1e-43 143.9 In-house 1-389 (486) Show / Hide 
Range on Protein: 1035-1232
Range on HMM: 1-389/486
Sequence Identity: 18% (72 aa)

FDERLVLGRGAFG---TVYKAEFKGP--------------------------TTVAVKILAQT-GLEVEHQFL-------------AELSTLGKIK----
     .||.|.||   .|||.| .|.                          |.||||.|  . . . | .|.             .|.. . . .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVDLQGWCHSR------------GKLMLVYEYLPNGS----LDRHLFSESEK--------------------------------------------
 |||.| | | |.              . .|.| || |.|.    |. .| . ..|                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------FLSWERRSQIIHGVAEAIKFLHQGH---EECILHRDIKAANVLLDKNFK-----------AKLGDFGLA-
                              .|. ...  . . .|..  .||. .   .  . |||. | |.|...| .           .|..||||. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RLFDHTDQGVLQTMTRVGTAG-------------------------YIAPELAF---------AGKATEKSDVYSFGVLILEIVT
     .  |. . .   ...  ||..                         . |||  .          || |.||||.|||||. ||.|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase LLEC_a-1.AA TKL-Unique 1040-1233 29 3.2e-43 149.93 In-house 4-224 (290) Show / Hide 
Range on Protein: 1040-1233
Range on HMM: 4-224/290
Sequence Identity: 29% (65 aa)

VLGRGAFGTVYKAEFKGPTTVAVKILAQ---TGLEVEHQFLAELSTLGKIK-HPNLVDLQGWCH----SRGKLMLVYEYLPNGSLDRHLFS--------E
..|.|..|.|||....| . ||.|...      .|..  |  |.... |.. |||.| . |.|.    . ... .| ||.| |||. .|          .
KIGEGGYGQVYKGKWRG-YPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

SEKFLSWERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANVLLDKN-----FKAKLGDFGLARLFDHTDQGVLQTM------TRVGTAGYIAPELAFA-
... |....| .... .| .  .||      |.|||.|  |.|.| |     ...|. ||||... .  ... . .       ||.|.. ..|||.    
NNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMN

-GKATEKSDVYSFGVLILEIVTG
  . .|||||||||.   ||.|.
FCQYSEKSDVYSFGIVLWEIATR
Kinase LLEC_a-1.AA Dicty4 1041-1233 32 3.1e-41 135.38 In-house 7-213 (277) Show / Hide 
Range on Protein: 1041-1233
Range on HMM: 7-213/277
Sequence Identity: 32% (70 aa)

LGRGAFGTVYKAEFKGPTTVAVKIL--AQTG--LEVEHQFLAELSTLGKIKHPNLVDLQGWCH----SRGKLMLVYEYLPNGSLDRHLFS-----ESEKF
.|.|.||.|||.  .| . ||||.|   ...  ..    |..| . ..|| |||.. . | |       ||.. | ||.| |.| . | .      ... 
IGKGSFGEVYKGTWRG-KEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIK

LSWERRSQ---IIHGVAEAIKFLHQGHEEC----ILHRDIKAANVLLDKNFKAKLGDFGLARLFDHTDQGVLQTMTRVGTAGYIAPELAFAGKATEKSDV
|.|... .   .   .|  .  ||     |    |.|||.|..| | |||...| .||||....    .    .|| .||... |||       .||.||
LDWPLIKRAMRMAFDAARGMNWLH-----CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YSFGVLILEIVTG
|||| .  ||.|.
YSFGIVLWEILTR
Kinase LLEC_a-1.AA LISK 1040-1236 26 6.6e-40 127.21 In-house 1-238 (296) Show / Hide 
Range on Protein: 1040-1236
Range on HMM: 1-238/296
Sequence Identity: 26% (65 aa)

VLGRGAFGTVYKAEFK--GPTTVAVKILAQ-----TGLEVEHQFLAELSTLGKIKHPNLVDLQGWCHS-RGKLMLVYEYLPNGSLDRHLFSESE--KFLS
..|.|.|| ||| . .  | . .|.| . .        | .. .| |. .. .. ||| |   | |    |.|..| ||   | | . |.....  . |.
EIGKGFFGKVYKGTHRQTG-QVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLP

WERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANVLLDKN----FKAKLGDFGLARLFDHTD-------------------------------QGVLQT
|. |  |  ..|..  .|   |. .|.||| |. |.|...|    ...|..|||.||..| ..                                   ..
WPQRVKIALDIACGMSYL---HSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRR

MTRVGTAGYIAPELAFAGKATEKSDVYSFGVLILEIVTGRRT
|| .||.   |||     . .|..||.|||.. .||.|....
MTICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA
Kinase LLEC_a-1.AA LRRK 1035-1235 23 1.5e-38 134.03 In-house 1-281 (351) Show / Hide 
Range on Protein: 1035-1235
Range on HMM: 1-281/351
Sequence Identity: 23% (68 aa)

FDERLVLGRGAFG-TVYKAEFKGP---------------------------TTVAVKILAQTG----------------------------------LEV
. .   .|||.|| .||.|...|.                           ..||.|..  ..                                  ...
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EHQFLAELSTLGKIKHPNLVDLQGWCHSRGKLMLVYEYLPNGSLDRHLFSES-EKF------LSWERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANV
 . |  |.. . . .|||.|.| | |..   |..| ||.|.|.|...|....  .|      .||  . .|   .|.....||  |   |.||| |  |.
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LL---D---------KNFKAKLGDFGLARLFDHTDQGVLQTMTRVGTAGYIAPELAFAG---KATEKSDVYSFGVLILEIVTGR-R
||   .          . .||..|||. |.|  ...  . ... ||. |. |||   ..     |||.|.||||... |..|.. .
LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGV-AKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH
Kinase LLEC_a-1.AA MLK 1035-1234 24 2.8e-38 130.45 In-house 1-233 (291) Show / Hide 
Range on Protein: 1035-1234
Range on HMM: 1-233/291
Sequence Identity: 24% (58 aa)

FDERLVLGRGAFGTVYKAEFKGPT----TVAVKILAQTGLEVEH------QFLAELSTLGKIKHPN----LVDLQGWCHSRGK-LMLVYEYLPNGSLDRH
...  ..| |.|| |.|..... .    .||||. ...  ..        .|  |   | ...|||     . . | |.. .. . .| ||...||| . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LFS-ESEKF-----------LSWERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANVLLD------KNFKAKLGDFGLARLFDHTDQGVLQTMTR-VGT
| . .|. .            . .   .. . .|... .||.     | |||.|  |.|.|      .. ..|  |||..| . ....    .|.   ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCT----NMMSNAGT

AGYIAPEL---AFAGKATEKSDVYSFGVLILEIVTGR
. . |||    . ..| .||.||.|.||.. |..|..
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase LLEC_a-1.AA TyrKc 1035-1303 26 1e-37 132.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 1035-1303
Range on HMM: 1-280/280
Sequence Identity: 26% (79 aa)

FDERLVLGRGAFGTVYKAEFKGPTTVAVKILAQTGLEVEHQFLAELSTLGKI--KHPNLVDLQGWCHSR-------GKLMLVYEYLPNGSLDRHLFSESE
     .||.||||.|||.. |  ..|||| |       .  |. |.. . |.  .|||.| | | | .        . ||.| || |.|.|. .| .  .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KFLSWERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANVLLDKNFKAKLGDFGLARLFDHT-------DQGVLQT--MTR-VGTAGYIAPELAFAGKAT
| |...   .. . .|.   .||.    .. |||. | |.|...|. .| .||||.|  ..        |  . ..   .. .      |||  . || |
K-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKSDVYSFGVLILEIVTGRRTISLACS----KTLIDRVWGMQESNALLEIVDERMRSSYNP-----DEARMLLHLGLTCCSMDADERPTMGECCKIL
.||||.||||.. || |  .  .        .   ..|    ..   ... ..       |       . |   . ..|.  |...|||. |.....
TKSDVWSFGVCMWEIFT--YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase LLEC_a-1.AA RIPK 1041-1234 25 1.3e-36 122.33 In-house 1-225 (290) Show / Hide 
Range on Protein: 1041-1234
Range on HMM: 1-225/290
Sequence Identity: 25% (59 aa)

LGRGAFGTVYKAEFKGPTTVAVKILAQTGLE--------VEHQFLAELSTLGKIKHPNLVDLQGWCHSR-----GK-LMLVYEYLPNGSLDRHLFSESE-
.|.|.||.|.||  .   .... ... ....        .. . . |   . |... . | . | |        .| . .| || .||||   | .... 
VGGGGFGEVFKARHRHWGDWVA-KKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPY

--KFLSWERRSQIIHGVAEAIKFLHQGHEECILHRDIKAANVLLDKNFKAKLGDFGLARLFDHT-DQG-------VLQTMTRV--GTAGYIAPELAF--A
  . . |  |  .|| ....  .|| .    |.||| | .|.|.| || .|. |||||        ..       |. .  .   ||  |..||. .   
QHHPDPWPLRCRMIHEISCGMCYLH-SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

GKA----TEKSDVYSFGVLILEIVTGR
 |.    |.|.|||||.... |. |..
KKPIKVVTPKYDVYSFAIVMWEVLTQK
Kinase LLEC_a-1.AA STE 1035-1234 23 4.3e-34 117.81 In-house 1-265 (359) Show / Hide 
Range on Protein: 1035-1234
Range on HMM: 1-265/359
Sequence Identity: 23% (64 aa)

FDERLVLGRGAFGTVYKAEFKGPT----------------TVAVKILA-QTGL----------------EVEHQFLAELSTLGKIK--HPNLVDLQGW--
..   ..|.|||||||||  . ..                 .|.|..  ..                  | . |.| |.... | .  ||| |   |   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----CHSRGKLMLVYEYLPNGSLD---RHLFSESE---------KFLSWERRSQIIHGVAEA-IKFLHQGHEECILHRDIKAANVLLDKNFKAKLGDFG
     ......| .. ||...||||   .| ..  .         .... .  . |.. . ..  ..||. |   | |||||.||.||     .|| |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LARLFDHT-------------DQGVLQTMTRVGTAGYIAPELAFA------GKATEKSDVYSFGVLILEIVTGR
..  ....             . .. .. | |||  . |||          .. ..|.|..|.| .|.| .||.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LLEC_a-1.AA TK 1283-1303 28 0.000208 9.85 In-house 466-486 (486) Show / Hide 
Range on Protein: 1283-1303
Range on HMM: 466-486/486
Sequence Identity: 28% (6 aa)

LTCCSMDADERPTMGECCKIL
. |.. |...|||. .. . |
QQCWHYDPEDRPTFSQLHEQL
Kinase LLEC_a-1.AA LISK 1278-1303 34 0.001435 7.24 In-house 271-296 (296) Show / Hide 
Range on Protein: 1278-1303
Range on HMM: 271-296/296
Sequence Identity: 34% (9 aa)

LLHLGLTCCSMDADERPTMGECCKIL
.| | . ||..| ..||.  |  ..|
FLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase LLEC_a-1.AA MLK 1285-1303 26 0.003554 7.02 In-house 273-291 (291) Show / Hide 
Range on Protein: 1285-1303
Range on HMM: 273-291/291
Sequence Identity: 26% (5 aa)

CCSMDADERPTMGECCKIL
| ..|. .||.. .. ..|
CWNQDPHKRPSFRQIVQHL
Kinase LLEC_a-1.AA Pkinase_Tyr 1285-1303 36 0.303009 4.84 Pfam 252-270 (270) Show / Hide 
Range on Protein: 1285-1303
Range on HMM: 252-270/270
Sequence Identity: 36% (7 aa)

CCSMDADERPTMGECCKIL
|   |...|||. |.  .|
CWHYDPEDRPTFSEIHEQL