Gene LLEC_h-1 (S.moellendorffii)

LLEC_h-1

Species: S.moellendorffii
Alias: LLEC_h-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LLEC

Sequence

Name Sequence Type Origin Length Description Download
LLEC_h-1.AA Protein None 669 None Fasta, JSON
LLEC_h-1.NA RNA None 2010 None Fasta, JSON
LLEC_h-1.kin_dom Protein Kinase Domain None 207 None Fasta, JSON

Protein domain

Protein domains of LLEC_h-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LLEC_h-1.AA TKL 348-618 21 2.7e-59 203.32 In-house 1-364 (364) Show / Hide 
Range on Protein: 348-618
Range on HMM: 1-364/364
Sequence Identity: 21% (84 aa)

LGRGGTSTVYKGFLQN------TPTSRIEVAVKDLQSNSPDHEAE-------------------------QQFREELNMISRVRHQNLVALQGWCHEHDK
.|.|| ..|||| ...      .  .  .|||| . |.. | . .                         ....||..|.|| ||.|.| . | | . ..
IGSGGFGEVYKGKWRGWGGKCPS-DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------LLLVYECMSKGS-LDKVLFTSASGSTNPLSWNQRFNIIRCVAEALRYLHE-----GLEK-RIVHRDIKAANVLLDERMT--------
             | .|.| ...|| |. ..            |.||..... .| .. |||      .  |  |.|||.| .|.|.|| .|        
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYN

------AKMGDFGLARLMQHTIG------------------SQTMTRAGTLGYISPELAY----------------SGRATEKSDVYSFGILVLEIVAGR
      .| .||||.| |... .                  ..|||. ||... .||.                  .. ..||.|||||||.  ||....
PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC

RAVDHRFAGDTKMVLLEWAGTLSQPAELVDPRIQDGIDMKQVER------------------------VIQLALRCCSWHSEERPTMRLCCQVL
|                ...  . | .. || ... . |  ...                        ...|. .|..   |.||..  . . |
R---------------PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LLEC_h-1.AA IRAK 344-618 29 1.2e-50 174.6 In-house 1-317 (317) Show / Hide 
Range on Protein: 344-618
Range on HMM: 1-317/317
Sequence Identity: 29% (97 aa)

FKE--VLGRGGTSTVYKGFLQNTP-TSRIEVAVK--DLQSNSPDHEAEQQFRE---ELNMISRVRHQNLVALQGWCHEHDKLLLVYECMSKGSLDKVLFT
| .  ..| ||  .||.| ..||. .    .|||      ..   | .|.|.    ||   .| || |.|.| | | | ... |||. |. |||   |  
FHKDNRIGEGGFGCVYRGQWKNTTGI----YAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWC

SASGST-NPLSWNQRFNIIRCVAEALRYLHEGLEKR----IVHRDIKAANVLLDERMTAKMGDFGLAR-------LMQHTI-GSQTMTRAGTLGYISPEL
 .   .  |||| ||. |    | ....||   ...    | |.||| ||.|||...|.| .||||.|       . ..|.    | .  ||. |  || 
QDGQCPPKPLSWHQRCSICWGTACGIQFLH---QNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEF

AY--SGRATEKSDVYSFGILVLEIVAGRRAVDHRFAG-----DTKMVLLEWAG----TLS------------------QPAELVDPRIQDGIDMKQVERV
 .  .|. | |.||||||| .||...|.|||. . .      | .... | .|    ..|                      ..|.|. .  . . ..  
IRDPQGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPP-CPPNMEKEM

IQLALRCCSWHSEERPTMRLCCQVL
 |.|..|      .|..|.   | |
CQCACCCGHHRANRRCDMAWVMQQL
Pkinase LLEC_h-1.AA Pkinase 342-548 26 2.6e-47 168.31 Pfam 1-209 (293) Show / Hide 
Range on Protein: 342-548
Range on HMM: 1-209/293
Sequence Identity: 26% (58 aa)

ADFKEVLGRGGTSTVYKGFLQNTPTSRIEVAVKDLQSNSPDHEAEQQFRE--ELNMISRVRHQNLVALQGWCHEHDKLLLVYECMSKG----SLDKVLFT
  .....|.|. ..|||.  ..|.    .|||| .   . ... .|. |   |. .  |..| | | | .|....|.. .| |.. .|    .|  .. |
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

SASGSTNPLSWNQRFNIIRCVAEALRYLHEGLEKRIVHRDIKAANVLLDERMTA----KMGDFGLARLMQHTIGSQTMTRAGTLGYISPELAY-SGRATE
...|.   .|...  .... ....| |.|.    .|.|||.| .|.|.|....     | .|||||.....  .| ..|..||..|..||.   .   . 
WRHGCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KSDVYSFGILVLEIVAGR
|.|..|.|... | . ||
KVDMWSCGCILYEMLCGR
Kinase LLEC_h-1.AA TKL-Unique 344-545 28 4.4e-40 139.07 In-house 1-222 (290) Show / Hide 
Range on Protein: 344-545
Range on HMM: 1-222/290
Sequence Identity: 28% (66 aa)

FKEVLGRGGTSTVYKGFLQNTPTSRIEVAVKDLQ-SNSPDHEAEQQFREELNMISRVR-HQNLVALQGWCH----EHDKLLLVYECMSKGSLDKVLFTSA
| ...|.|| ..||||        ...||.| .   ...  | .| |..|.| ... . | |.| . |.|.       .. .| |... |||..|| .. 
FWNKIGEGGYGQVYKGKWR-----GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNN

SGS-----TNPLSWNQRFNIIRCVAEALRYLHEGLEKRIVHRDIKAANVLLDER-----MTAKMGDFGLARLMQHTIGSQTM--------TRAGTLGYIS
  .      ..|...|| ......| .. |||  .|. | |||.|  |.|.|..     . .|  ||||...    . . .         || |.. ...
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLH-HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMA

PELAYS--GRATEKSDVYSFGILVLEIV
||.  .     .|||||||||| . ||.
PEVLRMNFCQYSEKSDVYSFGIVLWEIA
S_TKc LLEC_h-1.AA S_TKc 342-618 21 1.4e-39 138.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 342-618
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

ADFKEVLGRGGTSTVYKGFLQNTPTSRIEVAVKDLQSNSPDHEAEQQFREELNMISRVRHQNLVALQGWCHEHDKLLLVYECMSK--GSLDKVLFTSASG
 .. ...|.|. ..|||.   .   .  .||.| .          ...| |... .. .| |.| | ..... |.| .| |...   |.| ...    ..
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

STN-PLSWNQRFNIIRCVAEALRYLHEGLEKRIVHRDIKAANVLLDERMTAKMGDFGLARLMQHTIGSQTMTRAGTLGYISPELAYSGRATE-KSDVYSF
 .. |..  .   ... ...|| |.|   ...|.|||.| .|.||||  . | .||||||..        .|  ||. |..||.      .  |.|..|.
GLRFPFPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GILVLEIVAGRRAVDHRFAGDTKMVLLEWAGTLSQPAELVDPRIQDGIDMKQVERVIQLALRCCSWHSEERPTMRLCCQ---------VL
|... | ..|.   .      . .....  |                      . ....  .|. .  |.|||   . |          .
GCILYEMLCGYPPFP------QMQMMFKKIG---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LLEC_h-1.AA TK 342-618 16 5.1e-39 127.91 In-house 1-486 (486) Show / Hide 
Range on Protein: 342-618
Range on HMM: 1-486/486
Sequence Identity: 16% (79 aa)

ADFKEVLGRGGTS---TVYKGFLQNTP----------------------TSRIEVAVKDLQSNSPDHEAEQQ---------------FREELNMIS--RV
  . ..||.|      .|||| ... .                        ...|||| | . ......|..               . ||. | .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHQNLVALQGWCHEHDK------------LLLVYECMSKGS----LDKVLFTSASGSTN-----------------------------------------
.|.|.| | | |....             ...| |.|..|.    |.. | ..  . ..                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------PLSWNQRFNIIRCVAEALRYLHEG---LEKRIVHRDIKAANVLLDERMT-----------AKMGDFGLAR
                              .|.  |.  . . .|....|||.    .....||||. | |.|..|...           .| .||||.|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

L----MQHTIGS-QTMTRAGTLG----------------------------YISPELAY---------SGRATEKSDVYSFGILVLEIVA-G-RRAVDHR
     .   |.| .  .|... |                            . .||             |. |.||||.|||.|. ||.  |        
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

FA------GDTKMVLLEWAGT---------------LSQPA-ELVDP----RIQDGIDMKQVERVIQLALRCCSWHSEERPTMRLCCQVL
        | .   ..|   .               . .|. ..  .    |.   .  .  | . .| ..|...  |.|||.. . . |
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LLEC_h-1.AA MLK 342-548 25 6.3e-39 132.7 In-house 1-233 (291) Show / Hide 
Range on Protein: 342-548
Range on HMM: 1-233/291
Sequence Identity: 25% (60 aa)

ADFKEVLGRGGTSTVYKGFLQNTPTSRIEVAVKDLQSNSPDHEAE-----QQFREELNMISRVRHQN----LVALQGWCHEHDK-LLLVYECMSKGSLDK
 .|.|..| |.   |.||  .|.  .  .||||   ..     ..     ..|..| .  ....|.|     ... | |... . ...| | ...|||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

VLFTSASGST-----NP----LSWNQRFNIIRCVAEALRYLHEGLEKRIVHRDIKAANVLLDE------RMTAKMGDFGLARLMQHTIGSQTMTRAGTLG
|| .  |..      ..     .  . .|.   .|... |||. . | |.|||.|  |.|.||       .|.|  |||..| ....  .  | .|||. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YISPEL---AYSGRATEKSDVYSFGILVLEIVAGR
. .||    . ... .||.||.|.|..  |.....
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase LLEC_h-1.AA STE 342-548 22 1.7e-36 126.41 In-house 1-265 (359) Show / Hide 
Range on Protein: 342-548
Range on HMM: 1-265/359
Sequence Identity: 22% (63 aa)

ADFKEVLGRGGTSTVYKGFLQNT----PTSRI--------EVAVK--DLQSNSP-------------DHEAEQQFREELNMISRVR--HQNLVALQGWC-
 .. |..|.|.. ||||.   ..    .| ..         .|.|  .|.....             .|| .||. .|... .. .  |.| |   | . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HE------HDKLLLVYECMSKGSLDKVLF-TSASGSTNPLSW--------NQRFNIIRCVAEA-LRYLHEGLEKRIVHRDIKAANVLLDERMTAKMGDFG
.|      .|.| .. | |. ||||...  .   | .....         .|   |.| . .. | |||.     |.|||||.||.||     .|  |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LARLMQH---------------TIGSQTMTRAGTLGYISPELAYSGR------ATEKSDVYSFGILVLEIVAGR
..  ...               |..... | .||  . .||    ..       ..|.|..|.|....| . |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LLEC_h-1.AA LRRK 342-553 22 4.9e-34 117.78 In-house 1-285 (351) Show / Hide 
Range on Protein: 342-553
Range on HMM: 1-285/351
Sequence Identity: 22% (65 aa)

ADFKEVLGRGGTS-TVYKGFLQN-----------------------TPTSRIEVAVKDLQS----------NSPD----------------------HEA
  . | .||||.  .||.. ...                       .  .. .||.| .            || .                      ..|
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EQQFREELNMISRVRHQNLVALQGWCHEHDKLLLVYECMSKGSLDKVLFTSASGST----NPLSWNQRFNIIRCVAEALRYLHEGLEKR--IVHRDIKAA
 . || |. ..|. .| |.| | | |...  | .| | .. |.|...|. ... .       .||. .  |   .|....|||    ..  |.||| |  
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKSP

NVLL---D---------ERMTAKMGDFGLARLMQHTIGSQ-TMTRAGTLGYISPELAYSG---RATEKSDVYSFGILVLEIVAGR-RAVDH
|.||   .         . ..|| .|||. | |  ....  ...  |. |. .||    .     |||.|.||||..  |.. .. .. |.
NILLWSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDE
Kinase LLEC_h-1.AA Pkinase_Tyr 342-545 30 1.8e-33 113.98 Pfam 1-208 (270) Show / Hide 
Range on Protein: 342-545
Range on HMM: 1-208/270
Sequence Identity: 30% (66 aa)

ADFKEVLGRGGTSTVYKGFLQ-NTPTSRIEVAVKDLQSNSPDHEA--EQQFREELNMISRV-RHQNLVALQGWCH-EHDK--LLLVYECMSKGSLDKVLF
  | ..||.|   .|||| .       .|.|||| |  .. .||.   . | .|... .   .|.|.| | | |  . .   ...| | | .|.|.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

TSASGSTNPLSWNQRFNIIRCVAEALRYLHEGLEKRIVHRDIKAANVLLDERMTAKMGDFGLARLMQHTIGSQTMTRAGTLGYI-----SPELAYSGRAT
.    . .||.  .  .. . .|... ||.   .|...|||. | |.|..| ...| .||||||..  .  ..  .|... | .     .||    |. |
KHR-EDKQPLTMKDLLQMCWQIAKGMEYLE---SKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYY-YRKRGGGKLPIKWMAPECINYGKFT

EKSDVYSFGILVLEIV
.||||.|||.|  ||.
TKSDVWSFGVLMWEIF
Kinase LLEC_h-1.AA TK-Unique 342-545 28 1.1e-31 106.55 In-house 1-233 (294) Show / Hide 
Range on Protein: 342-545
Range on HMM: 1-233/294
Sequence Identity: 28% (67 aa)

ADFKEVLGRGGTSTVYKGFLQNTP---TSRIEVAVKDLQSNSPDHEAEQQFREELNMISRVR-HQNLVALQGWCHEHD-KLLLVYECMSKGSLDKVLFTS
  ...|.|.|  ..|..| . ...     .. |||| |. |. |.. .|.|  |..| . .  |.|.| . | | . |   ....| ...|.|.. | |.
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTD-KQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

A---------------------SGSTNPLSWNQRFNIIRCVAEALRYLHEGLEKRIVHRDIKAANVLLDERMTAKMGDFGLARLMQHTIGSQTMTRAGTL
.                     . .|.|.|  . ....  .| .. ||.. . |.|||||. | |||| |. ..| .|||.||  ...   ..|.. |..
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLAS-QRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRI

G--YISPELAY--SGRA-TEKSDVYSFGILVLEIV
   . .||  .   | . |.||||.|||.|  ||.
PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIF
Kinase LLEC_h-1.AA RIPK 348-550 25 3.3e-31 103.58 In-house 1-227 (290) Show / Hide 
Range on Protein: 348-550
Range on HMM: 1-227/290
Sequence Identity: 25% (61 aa)

LGRGGTSTVYKGFLQNTPTSRIEVAVKDLQSNSPDHE----AEQQFREELNMISRVRHQNLVALQGWCHEHDK------LLLVYECMSKGSLDKVLFTSA
.|.|| ..|.| .     . . .||.|   .  .. .     ...  ||  .  . |... | . | | . ..      . .| | | .||| ..| |  
VGGGGFGEVFKARHR---HWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKW

SGSTNPLSWNQRFNIIRCVAEALRYLHEGLEKR--IVHRDIKAANVLLDERMTAKMGDFGLARLMQHTIGSQTMT---------------RAGTLGYISP
.    |. |  |. .|  ....  |||    .   | ||| | .|.|.|  . .|  |||||  |.   .|. ..               | ||| |. |
PYQHHPDPWPLRCRMIHEISCGMCYLH---SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMM---WSHSHQDRCNQREVYSMKSKNRWGTLSYMPP

ELAY---SGR---ATEKSDVYSFGILVLEIVAGRRA
|.     . .   .|.|.|||||.|.. |. ... .
EHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LLEC_h-1.AA UTK 342-547 24 1.7e-30 101.53 In-house 1-236 (296) Show / Hide 
Range on Protein: 342-547
Range on HMM: 1-236/296
Sequence Identity: 24% (58 aa)

ADFKEVLGRGGTSTVYKGFLQNTP--TSRIEVAVKDLQSNSPDHEAEQ---QFREELN---MISRVR-HQNLVALQGWCHEHDKLLLVYECMSKGSLDKV
  . . ||.|   .|.|. ... .       ||||..|. ...  ..    .|.|| .   | .... |.|.. |.| |     ...|.|.|..|.|...
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LFTSAS---GSTNPLSWNQRFNIIRCVAEALRYLHEGLEKRIVHRDIKAANVLLDER-------MTAKMGDFG---LARLMQH--------TIGSQTMTR
| ...    . .  |.  ||    . .|... |||   ....||||. | |.|...        |..| .|||   ..|...              ... 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLH---SCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH

AGT--LGYISPELAYSG-RATEKSDVYSFGILVLEIVAG
..   .   .||  ... | |.||||.|||... ||...
QDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW
Kinase LLEC_h-1.AA TyrKc 342-618 22 3.2e-30 107.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 342-618
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

ADFKEVLGRGGTSTVYKGFLQNTPTSRIEVAVKDLQSNSPDHEAEQQFREELNMISRV--RHQNLVALQGWCHEH-------DKLLLVYECMSKGSLDKV
  ....||.|   .|||| .       |.|||| |....     .. |..|... ...  .|.|.|.| | | ..       . |..| | |..|.|.. 
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LFTSASGSTNPLSWNQRFNIIRCVAEALRYLHEGLEKRIVHRDIKAANVLLDERMTAKMGDFGLARLMQHT---------IGSQT--MTRA-GTLGYISP
|  .       |.. .  ..   .|.  .|||.    ...|||. | |.|..|. |.| .||||.|   .          . ...   ...   .   .|
LRKHRPK----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

ELAYSGRATEKSDVYSFGILVLEIVAGRRAVDHR-----FAGDTKMVLLEWAGTLSQPAELVDPRIQDGIDMKQVERVIQLALRCCSWHSEERPTMRLCC
|    |. |.||||.|||..  ||                  .  . ...  . . ||..   | .         . . |. ..|.    |.|||.. ..
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEIH

QVL
. .
ECF
Kinase LLEC_h-1.AA TK-Unique 600-618 42 0.239788 0.55 In-house 276-294 (294) Show / Hide 
Range on Protein: 600-618
Range on HMM: 276-294/294
Sequence Identity: 42% (8 aa)

CCSWHSEERPTMRLCCQVL
| .|  ||||. | . ..|
CWQWEPEERPSFRQIKHRL
Kinase LLEC_h-1.AA Pkinase_Tyr 595-618 29 0.834438 3.35 Pfam 247-270 (270) Show / Hide 
Range on Protein: 595-618
Range on HMM: 247-270/270
Sequence Identity: 29% (7 aa)

QLALRCCSWHSEERPTMRLCCQVL
.| ..|  .  |.|||.. . . |
DLMKQCWHYDPEDRPTFSEIHEQL