LRR10_d

Species: S.moellendorffii
Alias: LRR10_d
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR10

Sequence

Name Sequence Type Origin Length Description Download
LRR10_d.AA Protein None 1130 None Fasta, JSON
LRR10_d.NA RNA None 3393 None Fasta, JSON
LRR10_d.kin_dom Protein Kinase Domain None 202 None Fasta, JSON

Protein domain

Protein domains of LRR10_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR10_d.AA LRRNT_2 121-162 32 1.2e-10 37.47 Pfam 1-46 (46) Show / Hide
Range on Protein: 121-162
Range on HMM: 1-46/46
Sequence Identity: 32% (15 aa)

ETDEALVLLSFKRALS--LQ-VDALPDWDEAN-RQSFCSWTGVRCS
  |... ||.|| .|.      ..| .|.  .   . |||||| |.
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD

LRR_1 LRR10_d.AA LRR_1 190-212 40 0.000214 19.76 Pfam 1-26 (26) Show / Hide
Range on Protein: 190-212
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLQQLNLSD-N--SLSGNIPGE-LFSL
.|| |.||. |  .|.|.|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 215-237 37 0.04869 11.4 Pfam 1-26 (26) Show / Hide
Range on Protein: 215-237
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLTALNLSF-N--TLTGPIPST-IYAS
.|. |.||  |   ||| ||.  . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 239-261 40 0.001242 17.05 Pfam 1-26 (26) Show / Hide
Range on Protein: 239-261
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

NLESIDLSR-N--SLTGGVPVD-LGLL
||...|||. |  .||| .| . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 263-285 40 9.3e-05 21.04 Pfam 1-26 (26) Show / Hide
Range on Protein: 263-285
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLRVLRLEG-N--NITGSVPAS-LGNC
.|..| | | |  |.||..| | . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 287-309 33 0.06072 11.06 Pfam 1-26 (26) Show / Hide
Range on Protein: 287-309
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

QLVELSLIE-N--QLDGEIPEE-LGKL
.| .|.|   |  .| |.||.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 311-333 37 0.000366 18.93 Pfam 1-26 (26) Show / Hide
Range on Protein: 311-333
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLRYLRLYR-N--KLTGNVPGS-LSNC
.|..| | . |  .|||..| | . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 335-357 33 4.498659 4.43 Pfam 1-26 (26) Show / Hide
Range on Protein: 335-357
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

GIEELLVSE-N--FLVGRIPES-YGLL
 ...| .|  |   |.| ||.|    |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 359-381 40 0.000388 18.84 Pfam 1-26 (26) Show / Hide
Range on Protein: 359-381
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KVKLLYLWG-N--RLTGSIPSS-LSNC
. . |.| | |  .|||.||.| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 383-405 40 0.263454 8.8 Pfam 1-26 (26) Show / Hide
Range on Protein: 383-405
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ELVQLLLDG-N--SLTGPLPPE-LGNR
 |  | |.| |  .||| .||. . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 408-430 37 0.02915 12.19 Pfam 1-26 (26) Show / Hide
Range on Protein: 408-430
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

KLQILSIHS-N--ILSGVIPES-VANF
.||.|.. . |   |.| ||.|   |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 432-454 25 1.327184 6.31 Pfam 1-26 (26) Show / Hide
Range on Protein: 432-454
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SLHSLWSHE-N--RFSGSIPRS-LGAM
.| .|     |  ...|.|| | . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 480-502 37 0.003442 15.48 Pfam 1-26 (26) Show / Hide
Range on Protein: 480-502
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLQVLRLQE-N--QLEGEIPAT-LGFL
.||.| |.  |  .|.|.||   .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 504-526 37 0.011368 13.64 Pfam 1-26 (26) Show / Hide
Range on Protein: 504-526
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

DLQGLSLQS-N--RLEGRIPPE-LGRC
 || |.|.. |  .|.| |||. .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 528-550 33 0.002156 16.2 Pfam 1-26 (26) Show / Hide
Range on Protein: 528-550
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLNYLKLQD-N--RLVGTIPSN-LSQL
.| .| |.. |  .|.|.||.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 552-574 40 7.2e-05 21.44 Pfam 1-26 (26) Show / Hide
Range on Protein: 552-574
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

QLRNLDVSR-N--QLTGVIPAS-LSSC
.|. ||.|. |  .||| || | . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 576-598 40 0.027317 12.29 Pfam 1-26 (26) Show / Hide
Range on Protein: 576-598
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLENVDLSY-N--SLGGSIPPQ-VLKL
.|.  |||. |  .| |.|||    .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 601-623 37 0.014456 13.27 Pfam 1-26 (26) Show / Hide
Range on Protein: 601-623
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

LLSGFNLSH-N--RLTGEIPRD-FASM
 |   .||. |  .|||.|| . | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 625-647 40 0.057272 11.15 Pfam 1-26 (26) Show / Hide
Range on Protein: 625-647
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

LVQAIDLSA-N--QLTGFIPES-LGAC
  | .|||  |  .||| ||.| . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 649-671 48 0.003397 15.5 Pfam 1-26 (26) Show / Hide
Range on Protein: 649-671
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

GLAKLDLSS-N--LLTGEIPPA-LGDL
 | .||||. |   |||.|||  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 678-696 43 0.010247 13.8 Pfam 5-26 (26) Show / Hide
Range on Protein: 678-696
Range on HMM: 5-26/26
Sequence Identity: 43% (10 aa)

LNLSR-N--NITGSIPEK-LSKL
|.||. |  |.||.||.  . .|
LDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 720-742 37 0.023073 12.55 Pfam 1-26 (26) Show / Hide
Range on Protein: 720-742
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

DLTVLDISS-N--NLEGPIPGP-LASF
 |..||.|. |  ||.| ||   . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10_d.AA LRR_1 698-719 33 0.284805 8.68 Pfam 1-26 (26) Show / Hide
Range on Protein: 698-719
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ALSQLDLSH-N--QLSGFVPA--LDLP
 |  ||||. |  .|.| .|   .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL

Kinase LRR10_d.AA TKL 838-1033 25 1.3e-53 184.42 In-house 1-288 (364) Show / Hide
Range on Protein: 838-1033
Range on HMM: 1-288/364
Sequence Identity: 25% (77 aa)

VGVGALSSVYKAQLPG---------GRCIAVKKMAS----------------------------ARTSRKLFLRELHTLGTLRHRNLGRVIGYCSTPEL-
.| |. . |||... |         |. .||||. |                            |.  |. . .|.  .  ||| |. . .|||  |.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------MAIILEFMPNGSLDKQLHDHQSRLEAFSTWEVRYKIALGTAQGLEYLHH----QCSSP--VLHCDLKPSNILLDSELQ----------
            ..|. |..|.|||  .||           |..| ..||..|.|..|||      |  .  ..|.|||..|||.|. ..          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----SRISDFGISKVRVQ------------------NTRTTTSSFKGTIGYVAPEY-----SYSS-----------IPSTKGDVFSYGVVLLELVTGKRP
      |.|||.|..  |                  |.|.||..  ||... |||       |..             |.| ||.|.|.|| |..|..||
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP





Kinase LRR10_d.AA IRAK 832-1033 31 2.8e-44 153.41 In-house 1-223 (317) Show / Hide
Range on Protein: 832-1033
Range on HMM: 1-223/317
Sequence Identity: 31% (70 aa)

FSSSNVVGVGALSSVYKAQLPGGR-CIAVK-----KMASARTSRKLFLR---ELHTLGTLRHRNLGRVIGYCSTPELMAIILEFMPNGSLDKQLHDHQS-
|. .|. | |.   ||..|. .     |||     .. |   ... |.    || .. ..|| |.  . |||. ..    . ..||||||  .|. .   
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-RLEAFSTWEVRYKIALGTAQGLEYLHHQCSS-PVLHCDLKPSNILLDSELQSRISDFGISKVR----VQNTRTT----TSSFKGTIGYVAPEYSY--SS
  . . | |  | .|..||| |...||   .  |. | | |..|||||  ..  |.|||    .    .    |     || ..||  | .||. .  . 
CPPKPLS-WHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

IPSTKGDVFSYGVVLLELVTGKRP
. ..| ||.| |.||||..|| |.
QLTKKTDVYSFGIVLLEVLTGCRA

Kinase LRR10_d.AA TKL-Unique 834-1033 30 1e-43 151.53 In-house 1-233 (290) Show / Hide
Range on Protein: 834-1033
Range on HMM: 1-233/290
Sequence Identity: 30% (71 aa)

SSNVVGVGALSSVYKAQLPGGRCIAVKKMA----SARTSRKLFLRELHTLGTLR-HRNLGRVIGYCS----TPELMAIILEFMPNGSLDKQLHD--HQS-
 .|..| |. ..|||.  . |  .|.|. .    |  .... | .|. .. .|. | |. . .|||     .|  | |..|..| |||.. ||.    . 
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--RLEAFSTWEVRYKIALGTAQGLEYLHHQCSSPVLHCDLKPSNILLDSE-----LQSRISDFGISKVRVQNTRTTTS--------SFKGTIGYVAPEYS
  . .   ....|.|.|.  |||..|||| |. |..|.|||.||.|.|..     .. .|.|||.||.. .....|..        ...|.. ..|||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHH-CEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

YS--SIPSTKGDVFSYGVVLLELVTGKR------P
 .  .  |.| ||.|.|.|| |..|.|.      |
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP

Kinase LRR10_d.AA MLK 832-1033 27 1.4e-39 134.95 In-house 1-235 (291) Show / Hide
Range on Protein: 832-1033
Range on HMM: 1-235/291
Sequence Identity: 27% (65 aa)

FSSSNVVGVGALSSVYKAQLPGGR----CIAVKKMA-------SARTSRKLFLRELHTLGTLRHRN----LGRVIGYCSTPEL-MAIILEFMPNGSLDKQ
.  . ..|.|.  .|.|..  . .     .|||. .       .. .... | .|   |  |.|.|      .. | |. |.   .|..|....|||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHDHQSRLE---------AFSTWEVRYKIALGTAQGLEYLHHQCSSPVLHCDLKPSNILLDS------ELQSRISDFGISKVRVQNTRTTTSSFKGTIGY
||. .|  .         .  . ..  ..||  |.|..||| .   |. | |||..|||.|       ... .|.|||.|.   |.. |.  |..||  .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

VAPEY---SYSSIPSTKGDVFSYGVVLLELVTGKRP
 |||    . ..  | | ||.|.|||| |..|.. |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP

Kinase LRR10_d.AA Pkinase 832-1031 25 1.1e-38 137.81 Pfam 1-209 (293) Show / Hide
Range on Protein: 832-1031
Range on HMM: 1-209/293
Sequence Identity: 25% (55 aa)

FSSSNVVGVGALSSVYKAQLPGGRC-IAVKKMASARTSRKL---FLR--ELHTLGTLRHRNLGRVIGYCSTPELMAIILEFMPNG----SLDKQLH-DHQ
.    ..| |. ..|||..  | ..  |||..   ... .     .|  |.. .  |.| |  | .... ..  . ...|....|    .|   .. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SRLEAFSTWEVRYKIALGTAQGLEYLHHQCSSPVLHCDLKPSNILLDSELQS----RISDFGISKV-RVQNTRTTTSSFKGTIGYVAPEYSY-SSIPSTK
 ..  || ||.. .... ...||||.| .    ..|.||||.|||.|.. .     .|.|||..|. .     . ...| ||..|.|||    ..  ..|
GCFY-FSEWECK-FYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

GDVFSYGVVLLELVTGK
 |..|.|..| |...|.
VDMWSCGCILYEMLCGR

Kinase LRR10_d.AA RIPK 838-1033 26 8.2e-34 112.59 In-house 1-227 (290) Show / Hide
Range on Protein: 838-1033
Range on HMM: 1-227/290
Sequence Identity: 26% (61 aa)

VGVGALSSVYKAQLPGGRCIAVKKMAS---ARTS-----RKLFLRELHTLGTLRHRNLGRVIGYCSTP------ELMAIILEFMPNGSLDKQLHDHQSRL
|| |. . |.||.    .  ..|| .      |      |.  ..|   .  ||...  .. | |  .      .|..|  |.|.|||| . || . . .
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

EAFSTWEVRYKIALGTAQGLEYLHHQCSS-PVLHCDLKPSNILLDSELQSRISDFGISKVRVQNTRTT-----------TSSFK-GTIGYVAPEYSY--S
.    | .|  .   .. |  |||  .   |..| ||||.|||.|...   |.||| .. . . ....           .| .. ||. | .||      
HHPDPWPLRCRMIHEISCGMCYLH--SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

SIP----STKGDVFSYGVVLLELVTGKRP
. |    ..| || |...|. |. |.| |
KKPIKVVTPKYDVYSFAIVMWEVLTQKHP

Kinase LRR10_d.AA LRRK 832-1033 22 5.2e-33 114.11 In-house 1-282 (351) Show / Hide
Range on Protein: 832-1033
Range on HMM: 1-282/351
Sequence Identity: 22% (65 aa)

FSSSNVVGVGALS-SVYKAQLPG---------------------------GRCIAVKKMASAR-----------------------------------TS
. . . .|.|.   .||.| . |                           .  .|.||.   .                                   ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

RKLFLRELHTLGTLRHRNLGRVIGYCSTPELMAIILEFMPNGSLDKQLHDHQ-SRLEAF---S-TWEVRYKIALGTAQGLEYLHHQCSS-PVLHCDLKPS
  .| .|.. . .|.| |.   .|.|  |  .....|..|.|.|.. ||... ...  |   . .| ...||||  | |.|||| .  . |..|.|||. 
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGF-HFMKAHISWMLKLKIALQIAKGMEYLHSH--NPPIIHRDLKSP

NILL---D---------SELQSRISDFGISKVRVQNTRTT-TSSFKGTIGYVAPEYSY---SSIPSTKGDVFSYGVVLLELVTGK-RP
||||   .          .    |.||||| .  | .... .. . |..|..|||       .  ..| |..|.|..| ||.|.. .|
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP

Kinase LRR10_d.AA S_TKc 832-1102 20 1.8e-30 108.51 SMART 1-231 (231) Show / Hide
Range on Protein: 832-1102
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

FSSSNVVGVGALSSVYKAQLPG-GRCIAVKKMASARTSRKLFLRELHTLGTLRHRNLGRVIGYCSTPELMAIILEFMPN--GSLDKQLHDHQSRL--EAF
.   ...| || ..|||..  . ||  |.|..       . ..||.  |   .| |. . .... . . . ...|....  |.| . .......     |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

STWEVRYKIALGTAQGLEYLHHQCSSPVLHCDLKPSNILLDSELQSRISDFGISKVRVQNTRTTTSSFKGTIGYVAPEYSYSSIPST-KGDVFSYGVVLL
.  ..|. ..  ....|||.| .    ..|.||||.|||||.  .  |.|||....         ..| ||  |.|||       .. | |. | |..| 
PE-HARF-YMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELVTGKRPTGNFGDGTSLVQWARSHFPGEIASLLDETIVFDRQEEHLQILQVFAVALACTREDPQQRPTMQDVLA---------FL
|...|. |     .   . .  .                           ..      | . ||..|||  ..|.         ..
EMLCGYPPFP---QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LRR10_d.AA Dicty4-Unclassified 835-1033 32 5.4e-28 92.94 In-house 4-207 (263) Show / Hide
Range on Protein: 835-1033
Range on HMM: 4-207/263
Sequence Identity: 32% (69 aa)

SNVVGVGALSSVYKAQLPGGRCIAVKKMASARTSRK-----LFLRELHTLGTLRHRNLGRVIGYCSTP----ELMAIILEFMPNGSLDKQLH----DHQS
   .| |..| |.|     |. .||||. . . .        |..|   || . | || .. |||  |      | |. |||. | |    |    . | 
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

RLEAFSTWEVRYKIALGTAQGLEYLHHQCSSPVLHCDLKPSNILLDSELQSRISDFGISKVRVQNTRTTTSSFKGTIGYVAPEYSYSSIPSTKGDVFSYG
 .   .|  .  |.|.  |||. .||   .  . | |.| ||||.|     .| ||||| | . .. . |    ||    .||         | ||.||.
PIKLDDTLII--KYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRV-IDFNFNMT-TIAGTPKWESPECLMHESYNQKSDVYSYA

VVLLELVTGKRP
..| ||.||  |
MMLYELATGDEP

Kinase LRR10_d.AA Dicty4 827-1033 28 5.9e-28 90.46 In-house 1-216 (277) Show / Hide
Range on Protein: 827-1033
Range on HMM: 1-216/277
Sequence Identity: 28% (64 aa)

IATDNFSSSNVVGVGALSSVYKAQLPGGRCIAVKKMASARTS--RKL---FLRELHTLGTLRHRNLGRVIGYCS----TPELMAIILEFMPNGSLDKQLH
|.....      | |....|||.    |   ||||. .  .    ..   |..| | .. .|| |.    |.|     .|. | |  |.|| |.| . ||
INIEQR-----IGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLH

D----HQSRLEAFSTWEVRYK---IALGTAQGLEYLHHQCSSPVLHCDLKPSNILLDSELQSRISDFGISK-VRVQNTRTT-TSSFKGTIGYVAPEYSYS
|     |.. .  . |. . .   .|. .|.|. .||  | . ..| |||..|.| |  ..  ..|||.|.  .   . .. ... .|| ...|||   .
DKPSEQQQSIK--LDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMH

SIPSTKGDVFSYGVVLLELVTGKRP
     | ||.|.| || |..|.. |
QPYNEKADVYSFGIVLWEILTRQEP

Kinase LRR10_d.AA TK 832-1033 14 7.9e-26 82.93 In-house 1-394 (486) Show / Hide
Range on Protein: 832-1033
Range on HMM: 1-394/486
Sequence Identity: 14% (57 aa)

FSSSNVVGVGALS---SVYKAQLPGGR----------------------------CIAVKKMASARTSR-KL------------FLRELHTLGTLR----
    .. | |.      |||... |..                             ....|  .| ... ..            ||.|.. .  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLGRVIGYCSTP------------ELMAIILEFMPNGS----LDKQLHDHQSRLEA-----------------------------------------
 | |. | .|.|. .            | . |..|.||.|.    |.. |...  .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------FSTWEVRYKIALGTAQGLEYLHHQ-CSSP---VLHCDLKPSNILLDSELQ-----------SRISDFGIS
                              . | . .  ...  |.|.|||| . |.     . | ||   |.|......            .|.||| |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-------VRVQNTRTTTSSFKGTIGY--------------------------VAPEYSYSSI---------PSTKGDVFSYGVVLLELVT-GKRP
.        ....    ...  .. |                            |||   . .          .|| ||.|.||.. |..| |. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP

Kinase LRR10_d.AA DRK 872-1029 33 4.3e-23 75.07 In-house 44-197 (258) Show / Hide
Range on Protein: 872-1029
Range on HMM: 44-197/258
Sequence Identity: 33% (54 aa)

FLRELHTLGTLRHRNLGRVIGYCSTPELMAIILEFMPNGSLDKQLHDHQSRLEAFSTWEVRYKIALGTAQGLEYLHHQCSSPV-LHCDLKPSNILLDSEL
| ||   .  ||| |    .| |  |    |. |.|| ||| . |||    ..    |  . ....  | |. |||  |. |. .| |||  | | |   
FHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMD----WPLMKQMMFDCAKGMIYLH--CCNPIIIHRDLKSHNLLVDEHW

QSRISDFGISK-VRVQNTRTTTSSFKGTIGYVAPEYSYSSIPSTKGDVFSYGVVLLELVT
|  ..||| |   .    ....    || . .|||   .     | ||.|...|| |.||
QVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT

Kinase LRR10_d.AA TyrKc 832-1102 23 9.1e-18 64.55 SMART 1-280 (280) Show / Hide
Range on Protein: 832-1102
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FSSSNVVGVGALSSVYKAQLPGGRCIAVKKMASARTSRKLFLRELHTLGTL--RHRNLGRVIGYCSTP-------ELMAIILEFMPNGSLDKQLHDHQSR
 .   . | ||   |||...   .  |||.. .    |. |.||.  .  |  .| |. | .|.|...       | . |..|.||.|.|.. |..|. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LEAFSTWEVRYKIALGTAQGLEYLHHQCSSPVLHCDLKPSNILLDSELQSRISDFGISKVRVQN------TRTTTS----SFK--GTIGYVAPEYSYSSI
     ...   ....  |.| ||||..   .. | ||   |.|...... .||||| |.           . . ..    . |    |   |||    ..
----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

PSTKGDVFSYGVVLLELVT-GKRPTGN----FGDGTSLVQWARSH-FPGEIASLLDETIVFDRQEEHLQILQVFAVALACTREDPQQRPTMQDVLAFL
 .|| ||.|.||.. |. | |. |  .    . . . .... ..   .   .. . . . |           .. . . | .||| .|||....  ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF-----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase LRR10_d.AA Pkinase_Tyr 832-981 25 7.8e-17 57.63 Pfam 1-159 (270) Show / Hide
Range on Protein: 832-981
Range on HMM: 1-159/270
Sequence Identity: 25% (42 aa)

FSSSNVVGVGALSSVYKAQLP-----GGRCIAVKKM--ASARTS--RKLFLRELHTLGTL-RHRNLGRVIGYCS-TPEL--MAIILEFMPNGSLDKQLHD
 .   . | ||  .|||. .      ..   |||..   .      |. |.||. .. .| .| |. | .| |.   |   . |..|.||.|.|.. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

HQSRLEAFSTWEVRYKIALGTAQGLEYLHHQCSSPVLHCDLKPSNILLDSELQSRISDFGISK
| .  ..... .   ....  |.|.|||. .      | ||   |.|...... .|.||| ..
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLAR

Kinase LRR10_d.AA TK 1077-1102 26 9e-06 14.42 In-house 461-486 (486) Show / Hide
Range on Protein: 1077-1102
Range on HMM: 461-486/486
Sequence Identity: 26% (7 aa)

VFAVALACTREDPQQRPTMQDVLAFL
.. . . | ..||..|||..... .|
YYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase LRR10_d.AA DRK 1084-1104 52 1e-05 15.48 In-house 238-258 (258) Show / Hide
Range on Protein: 1084-1104
Range on HMM: 238-258/258
Sequence Identity: 52% (11 aa)

CTREDPQQRPTMQDVLAFLTR
|  ||||.||.||..|  |  
CWNEDPQHRPSMQECLERLEA

Kinase LRR10_d.AA TKL 1084-1102 42 0.000577 10.18 In-house 346-364 (364) Show / Hide
Range on Protein: 1084-1102
Range on HMM: 346-364/364
Sequence Identity: 42% (8 aa)

CTREDPQQRPTMQDVLAFL
|  .||..||..|..|  |
CWDHDPEKRPSFQEILKRL

Kinase LRR10_d.AA Dicty4-Unclassified 1084-1102 42 0.000886 8.78 In-house 245-263 (263) Show / Hide
Range on Protein: 1084-1102
Range on HMM: 245-263/263
Sequence Identity: 42% (8 aa)

CTREDPQQRPTMQDVLAFL
|  .||. |||| ..   |
CWHNDPNKRPTMNQIIQYL

Kinase LRR10_d.AA LRRK 1084-1104 28 0.001061 8.95 In-house 331-351 (351) Show / Hide
Range on Protein: 1084-1104
Range on HMM: 331-351/351
Sequence Identity: 28% (6 aa)

CTREDPQQRPTMQDVLAFLTR
|  .||..||...... .|  
CWQHDPKKRPHFSQIVKRLSQ

Kinase LRR10_d.AA TKL-Unique 1083-1102 35 0.002125 8.06 In-house 271-290 (290) Show / Hide
Range on Protein: 1083-1102
Range on HMM: 271-290/290
Sequence Identity: 35% (7 aa)

ACTREDPQQRPTMQDVLAFL
.| . ||.|||. ....  |
QCWHHDPSQRPSFDEIIHRL

Kinase LRR10_d.AA MLK 1087-1102 31 0.006408 6.12 In-house 276-291 (291) Show / Hide
Range on Protein: 1087-1102
Range on HMM: 276-291/291
Sequence Identity: 31% (5 aa)

EDPQQRPTMQDVLAFL
.|| .||... .. .|
QDPHKRPSFRQIVQHL

Kinase LRR10_d.AA Dicty4 1087-1104 30 0.008947 5.28 In-house 258-277 (277) Show / Hide
Range on Protein: 1087-1104
Range on HMM: 258-277/277
Sequence Identity: 30% (6 aa)

EDPQQRPTMQDVLAF--LTR
.|||.||... ..    |  
HDPQHRPSFEEIIQRRILEH

Kinase LRR10_d.AA Pkinase_Tyr 1086-1102 35 0.019172 8.9 Pfam 254-270 (270) Show / Hide
Range on Protein: 1086-1102
Range on HMM: 254-270/270
Sequence Identity: 35% (6 aa)

REDPQQRPTMQDVLAFL
..||..|||..... .|
HYDPEDRPTFSEIHEQL

Kinase LRR10_d.AA Pkinase_Tyr 1012-1033 47 0.081582 6.77 Pfam 192-214 (270) Show / Hide
Range on Protein: 1012-1033
Range on HMM: 192-214/270
Sequence Identity: 47% (11 aa)

STKGDVFSYGVVLLELVT-GKRP
.|| || |.||.. |..| |. |
TTKSDVWSFGVLMWEIFTYGEQP

Kinase LRR10_d.AA Pkinase 1088-1102 35 9.033326 0.27 Pfam 277-293 (293) Show / Hide
Range on Protein: 1088-1102
Range on HMM: 277-293/293
Sequence Identity: 35% (6 aa)

DPQQRPTMQDVLAF--L
||..||| ...|    .
DPKKRPTAEQILQHPWF