Gene LRR10_a (S.moellendorffii)

LRR10_a

Species: S.moellendorffii
Alias: LRR10_a
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR10

Sequence

Name Sequence Type Origin Length Description Download
LRR10_a.AA Protein None 948 None Fasta, JSON
LRR10_a.NA RNA None 2847 None Fasta, JSON
LRR10_a.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of LRR10_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR10_a.AA LRRNT_2 44-85 30 8.5e-07 24.98 Pfam 1-46 (46) Show / Hide 
Range on Protein: 44-85
Range on HMM: 1-46/46
Sequence Identity: 30% (14 aa)

NGEEVQVLLEFRKCIKA-DP-SGLLDKWALRR--SPVCGWPGIACR
. ...| ||.|.. .   || .| |  |      |  | | |. | 
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR10_a.AA LRR_1 88-110 33 2.090912 5.61 Pfam 1-26 (26) Show / Hide 
Range on Protein: 88-110
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RVRALNLSG-L--GLEGAISPQ-IAAL
. . |.|||     |.| |.|  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 112-134 40 0.00035 19.0 Pfam 1-26 (26) Show / Hide 
Range on Protein: 112-134
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

HLAVLDLQT-N--NLSGSIPSE-LGNC
.| .|||.  |  ||.|.||.. . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 136-158 48 0.014363 13.28 Pfam 1-26 (26) Show / Hide 
Range on Protein: 136-158
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

SLQGLFLAS-N--LLTGAIPHS-LGNL
.|| | | . |   ||| ||.| . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 160-182 40 0.022192 12.61 Pfam 1-26 (26) Show / Hide 
Range on Protein: 160-182
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLRGLHLHE-N--LLHGSIPPS-LGNC
.|. |.|   |   | |.|||| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 184-206 37 0.186738 9.33 Pfam 1-26 (26) Show / Hide 
Range on Protein: 184-206
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

LLTDLELAK-N--GLTGSIPEA-LGRL
 |. | |   |   |||.||.  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 208-230 40 0.006895 14.41 Pfam 1-26 (26) Show / Hide 
Range on Protein: 208-230
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

MLQSLYLFE-N--RLTGRIPEQ-IGGL
 ||.|.|   |  .||| ||.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 232-254 44 0.000205 19.82 Pfam 1-26 (26) Show / Hide 
Range on Protein: 232-254
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

RLEELILYS-N--KLSGSIPPS-FGQL
.|..| | . |  .|.|.|||| | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 257-276 37 0.62083 7.48 Pfam 4-26 (26) Show / Hide 
Range on Protein: 257-276
Range on HMM: 4-26/26
Sequence Identity: 37% (9 aa)

ELLLYS-N--RLTGSLPQS-LGRL
.| | . |  .|||..| | .  |
HLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 278-300 40 0.0001 20.93 Pfam 1-26 (26) Show / Hide 
Range on Protein: 278-300
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLTTLSLYD-N--NLTGELPAS-LGNC
.|..|.| . |  ||||..| | . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 302-324 33 24.799464 1.8 Pfam 1-26 (26) Show / Hide 
Range on Protein: 302-324
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

MLVDVELQM-N--NFSGGLPPS-LALL
 |    |.  |  |..| .||| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 326-348 25 0.552344 7.66 Pfam 1-26 (26) Show / Hide 
Range on Protein: 326-348
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

ELQVFRMMS-N--RLSGPFPSA-LTNC
 ||.  . . |  .|.| .|.  . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 350-372 29 0.000322 19.13 Pfam 1-26 (26) Show / Hide 
Range on Protein: 350-372
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

QLKVLDLGD-N--HFSGNVPEE-IGSL
.|..|||.. |  ...|..|.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 374-396 37 0.039298 11.73 Pfam 1-26 (26) Show / Hide 
Range on Protein: 374-396
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLQQLQLYE-N--EFSGPIPSS-LGTL
.|| | |   |   ..| ||.| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 398-420 44 0.002553 15.94 Pfam 1-26 (26) Show / Hide 
Range on Protein: 398-420
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

ELYHLAMSY-N--RLSGSIPDS-FASL
 | || .|. |  .|.|.||.| | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 422-445 25 0.088492 10.48 Pfam 1-26 (26) Show / Hide 
Range on Protein: 422-445
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SIQGIYLHG-N--YLSGEVPFAALRRC
..| ..| | |   |.|..|  ..  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 457-474 40 0.864574 6.97 Pfam 6-26 (26) Show / Hide 
Range on Protein: 457-474
Range on HMM: 6-26/26
Sequence Identity: 40% (9 aa)

DLSH-N--SLAGPIPSW-IKNM
|||. |  .| | ||.. . |.
DLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 476-498 25 0.232874 8.99 Pfam 1-26 (26) Show / Hide 
Range on Protein: 476-498
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

KVLSISLAS-N--SLSGEIPSS-ISDC
.  ...| . |  .|.|.||.| .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 500-522 44 0.000534 18.35 Pfam 1-26 (26) Show / Hide 
Range on Protein: 500-522
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

GLQSLDLSS-N--GLVGQIPEG-LGTL
 ||.||||. |   |.|.||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 524-546 51 6.2e-05 21.67 Pfam 1-26 (26) Show / Hide 
Range on Protein: 524-546
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

SLVTLDLSS-N--NLTGRIPKS-LATL
.| .||||. |  |||| ||.| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_a.AA LRR_1 548-572 35 0.510937 7.78 Pfam 1-26 (26) Show / Hide 
Range on Protein: 548-572
Range on HMM: 1-26/26
Sequence Identity: 35% (10 aa)

GLSSLNVSM-N--NLQGPVPQEGVFLKL
 | .|..|  |  ||.| .| .  | .|
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
Kinase LRR10_a.AA TKL 679-943 20 1e-51 178.12 In-house 1-364 (364) Show / Hide 
Range on Protein: 679-943
Range on HMM: 1-364/364
Sequence Identity: 20% (79 aa)

LGAGGFSKVYKGTNALNG--------ETVAVKVLSS----------------------------SCVDLKSFVSEVNMLDVLKHRNLVKVLGYCWTWEV-
.| |||..||||.   .|        ..||||...|                            ..   . .. |..|.  |.| |.|. .|||   .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KALVLEFMPNGSLASFAARNSHRLDWKIRLTIAEGIAQGLYYMHNQL-----KDPVIHCDLKPGNVLLDAGLS--------------P
             ..| |..|.||| ..         |  |. .| .||.|..|.|..      | |.||.|||. |.|.|  .               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

HVADFGLSKLVHGE-----------------NGETSVSAFKGTIGYAPPEY----------------GTSYRVSTKGDVYSYGVVLLELLTGVAPSS--E
 ..|||||. ....                 |...  .   ||... .||                   ..  |.| ||||.|.|| |.||.  | .   
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

CLRVRGQ----TLREWILDEGREDLCQ-----VLDPALALVDTDHGVEIQNLVQVGLLCTAYNPSQRPSIKDVVAML
.  . .|       ... |.|.  ..      ..      .  .     . . .    | ...|..||| ....  |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH----K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR10_a.AA IRAK 673-869 33 8.1e-46 158.53 In-house 1-220 (317) Show / Hide 
Range on Protein: 673-869
Range on HMM: 1-220/317
Sequence Identity: 33% (74 aa)

FSEANLLGAGGFSKVYKGTNALNGET--VAVK----VLSSSCVDLK-SFVS---EVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPNGSL-ASFAARN
|...|..| |||  ||.|   ....|  .|||    . ..|.  .. .| .   |.  .  . | |.| ..|||   .   || ..|||||| .  ....
FHKDNRIGEGGFGCVYRG--QWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQD

-SHR---LDWKIRLTIAEGIAQGLYYMHNQL-KDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLV----HGENGET---SVSAFKGTIGYAPPEYGT--S
 .     | | .|. |..|.| |... |.   . |.|| | |. |.|||. . |  .||||        | | ..     .| ..||  | |||. .  .
GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQ

YRVSTKGDVYSYGVVLLELLTG
 . ..| |||| |.||||.|||
GQLTKKTDVYSFGIVLLEVLTG
Kinase LRR10_a.AA TKL-Unique 676-876 30 8.2e-44 151.87 In-house 2-237 (290) Show / Hide 
Range on Protein: 676-876
Range on HMM: 2-237/290
Sequence Identity: 30% (72 aa)

ANLLGAGGFSKVYKGTNALNGETVAVKVLSS---SCVDLKS-FVSEVNMLDVLK-HRNLVKVLGYCW--TWEVK--ALVLEFMPNGSLASFAA-------
 |..|.||...||||.   .|. ||.|...    |  ...  | .||| . .|. | |.|.  |||   .   .   .|.|..| ||| .  .       
WNKIGEGGYGQVYKGK--WRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--RNSHRLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAG-----LSPHVADFGLSKLVHGENGETSV-------SAFKGTIGYAPPEYG
  .|.. |... |...|. ||||.|| |.  .  .||.|||. |.|.| .     ..  ..||||||.   .| .|.        . ..|.. ...||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

TS--YRVSTKGDVYSYGVVLLELLTGVA------PSSEC
..  .  |.| ||||.|.|| |..|.        | ...
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGM
Kinase LRR10_a.AA Pkinase 673-872 24 2.6e-42 150.67 Pfam 1-211 (293) Show / Hide 
Range on Protein: 673-872
Range on HMM: 1-211/293
Sequence Identity: 24% (54 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCVDLKSFVS-----EVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPNG----SLASFAA-RNS
.     .|.|.|..|||...  .|..||||... .  . .  ..     |. ..  |.| | |. .... .     .|.|....|    .|...   ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HRL--DWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSP----HVADFGLSKLVHGENGETSVSAFKGTIGYAPPEY-GTSYRVSTKGD
 ..  ...    ..  |..||.|.|..    .||.|||| |.|.|    .    ...||||.|..  .   .  . | ||..|..||   ..   ..| |
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSYGVVLLELLTGVAP
..|.|..| |.|.|  |
MWSCGCILYEMLCGRPP
Kinase LRR10_a.AA RIPK 679-872 27 3.4e-38 127.74 In-house 1-227 (290) Show / Hide 
Range on Protein: 679-872
Range on HMM: 1-227/290
Sequence Identity: 27% (64 aa)

LGAGGFSKVYKGTNALNGETVAVKVLSSSCVD-------LKSFVSEVNMLDVLKHRNLVKVLGYCWTWEV------KALVLEFMPNGSLASFAARNS---
.| |||..|.| . .  |. ||.|.  .  ..        .    |. ..  |.... |...| |   |        ..| |.|.||||. | .. .   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-HRLDWKIRLTIAEGIAQGLYYMHNQLKD-PVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGE--NG--------ETSVSAFK-GTIGYAPPEYGT---
 | . |. |  .   |. |  | |.  .. |.|| ||||.|.|.|. .   .|||||..   .   ..          . |... ||. | |||      
HHPDPWPLRCRMIHEISCGMCYLHS--MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

SYR---VSTKGDVYSYGVVLLELLTGVAP
. .   |..| ||||...|. |.||.  |
KKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LRR10_a.AA S_TKc 673-946 21 2.1e-35 124.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 673-946
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCVDLKSFVSEVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPN--GSLASFAARNSHR-----L
.   ...| |.|.||||...   |. ||.|...      ... .|...|   .| |.|| .... . .   .|.|....  |.| ..  .. ..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGENGETSVSAFKGTIGYAPPEYGTSYRVST-KGDVYSYGVVLL
.      ..  |...| |.|.. .  .||.|||| |.|||      ..||||....         . | ||  | .||       .. | |..| |..| 
PE-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELLTGVAPSSECLRVRGQTLREWILDEGREDLCQVLDPALALVDTDHGVEIQNLVQVGLLCTAYNPSQRPSIKDVVA------MLEQL
|.|.|  | .       |.. . |.                        |  ....    |  ..|..||.. .. .      . . .
EMLCGYPPFP-----QMQMMFKKIG----------------------SPEAKDFIR---KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR10_a.AA MLK 673-869 27 4.5e-31 105.09 In-house 1-232 (291) Show / Hide 
Range on Protein: 673-869
Range on HMM: 1-232/291
Sequence Identity: 27% (65 aa)

FSEANLLGAGGFSKVYKGTNALNGET-----VAVKVLSSSC---VD----LKSFVSEVNMLDVLKHRN----LVKVLGYCWTWEV-KALVLEFMPNGSLA
. .   .|.|.| ||.||.    ...     ||||   ..    .|     . |  |.. | .|.|.|     ....| |   .   ..|.|....|||.
IQFHEWIGSGSFGKVWKGR--WRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

SFA--AR-----------NSHRLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDA------GLSPHVADFGLSKLVHGENGETSVSAFKGT
..   ||           |. . |    ...|  .|.|. | |.....|.|| |||. |.|.|.      ..   ..|||.|. .| ... |    ..||
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWH-QMC-TNMMSNAGT

IGYAPPEY---GTSYRVSTKGDVYSYGVVLLELLTG
  .  ||      . ..| | ||.|.|||| |.||.
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTR
Kinase LRR10_a.AA LRRK 673-869 22 6.4e-28 95.84 In-house 1-278 (351) Show / Hide 
Range on Protein: 673-869
Range on HMM: 1-278/351
Sequence Identity: 22% (66 aa)

FSEANLLGAGGFS-KVYKGTNALN--------------------------GETVAVKVLSS-----------------------------------SCVD
. . ...| |||  .||...   .                          ...||.|..                                     .|  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LKSFVSEVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPNGSLASFAARNS-HR-------LDWKIRLTIAEGIAQGLYYMHNQLKD-PVIHCDLKPGN
. .|  || ..  |.| |.|. .|.|   .  ..|.|..|.|.| .|   .. ..       ..| ..| ||  || |. |.|.  .. |.||.|||. |
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS--HNPPIIHRDLKSPN

VLL---D---------AGLSPHVADFGLSK---LVHGENGETSVSAFKGTIGYAPPEYGT-----SYRVSTKGDVYSYGVVLLELLTG
.||   .         |    ..||||.|     .| .   ..|    |..|.  ||        .|  ..| |.||.|..| ||||.
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV----GNPGWMAPEIMRYNGEEEY--TEKVDCYSFGMILWELLTR
Kinase LRR10_a.AA TK 673-868 15 3.2e-27 87.68 In-house 1-389 (486) Show / Hide 
Range on Protein: 673-868
Range on HMM: 1-389/486
Sequence Identity: 15% (60 aa)

FSEANLLGAGGFS---KVYKGTNALNG-------------------------ETVAVKVLSSSC-VDLKS-----------------FVSEVNMLD--VL
    . ||.| |    .||||.    .                         ..||||.| . .  . .                  ...|  |..  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KHRNLVKVLGYCWTWEVK------------ALVLEFMPNGS----LASFAARNS----------------------------------------------
.| |.|. .|.|   | |             .|.|.||.|.    | ..  ...                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------------------------HRLDWKIRLTIAEGIAQGLYYMHNQ----LKDPVIHCDLKPGNVLLDAGLS-----------PHVADFGLS
                             |.|. . .| ..  ||.|. |.| .        ..| ||   |.|.. ..              .||||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-------LVHGENGETSVSAFKGTIG-------------------------YAPPEYGT---------SYRVSTKGDVYSYGVVLLELLT
.         ......  ..  .|| .                         . .||  .           . .|| ||.|.||.. |..|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase LRR10_a.AA Dicty4-Unclassified 676-869 32 6.4e-26 85.73 In-house 4-204 (263) Show / Hide 
Range on Protein: 676-869
Range on HMM: 4-204/263
Sequence Identity: 32% (69 aa)

ANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCVDLK-----SFVSEVNMLDVLKHRNLVKVLGYCWTW----EVKALVLEFMPNGSLASFAA------R
   .| | ||||.||     |  |||| . .            |  || .|  . | ||||. |||            | |||. | |            
DQFIGKGHFSKVHKG--NWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

NSHRLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGENGETSVSAFKGTIGYAPPE--YGTSYRVSTKGDVYS
 . .||  . . .|  ||||. ..|      .|| |.|  |.|.|      .||||.|  .      | .    ||     ||   . ||    | ||||
QPIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIA---GTPKWESPECLMHESY--NQKSDVYS

YGVVLLELLTG
|...| ||.||
YAMMLYELATG
Kinase LRR10_a.AA Dicty4 673-872 31 1.3e-25 82.56 In-house 1-216 (277) Show / Hide 
Range on Protein: 673-872
Range on HMM: 1-216/277
Sequence Identity: 31% (68 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCVD-----LKSFVSEVNMLDVLKHRNLVKVLGYCW----TWEVKALVLEFMPNGSLASFAAR---
    ...| |.|..|||||    |  ||||.| .  ..     |..|  ||. .  . | |... .|.|     . .    | |.|| |.|.|       
INIEQRIGKGSFGEVYKGT--WRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---NSHRLDWKIRLT---IAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSK-LVHGENGETSVSAFKGTIGYAPPEYGTSYRVSTK
    |  |||  ..    .|  .|.|. . |.   . .|| |||. | | |. .   |.|||||.    .|.  .  .. .|| ..  ||   . .   |
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEK

GDVYSYGVVLLELLTGVAP
 ||||.| || |.||. .|
ADVYSFGIVLWEILTRQEP
Kinase LRR10_a.AA DRK 680-868 32 2.7e-23 75.76 In-house 8-197 (258) Show / Hide 
Range on Protein: 680-868
Range on HMM: 8-197/258
Sequence Identity: 32% (64 aa)

GAGGFSKVYKGTNALNGETVAVKVLSSSCVD----LKSFVSEVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPNGSLASFAARNSHRLDWKIRLTIAE
| |..  |. ||    |  |||| |    ..    |. |  |.|..  | | | .  .| |        . |.|| |||..     |  .||  .. .. 
GRGNYGEVFRGT--WRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMF

GIAQGLYYMHNQLKDPVI-HCDLKPGNVLLDAGLSPHVADFGLSK----LVHGENGETSVSAFKGTIGYAPPEYGTSYRVSTKGDVYSYGVVLLELLT
 .| |. | |.   .|.| | |||  | | |      |||||||             | .    || .   ||   . |   | ||||...|| |..|
DCAKGMIYLHC--CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC----GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT
Kinase LRR10_a.AA TyrKc 673-943 24 1.1e-20 75.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 673-943
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCVDLKSFVSEVNMLDVL--KHRNLVKVLGYCWTW-------EVKALVLEFMPNGSLASFAARNSH
 .    || | | .|||||     ..||||.| ...  .. | .| ...  |  .| |.|. .|.| .        |   .|.|.||.|.| ..  .. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGE------NGETSVS---AFK--GTIGYAPPEYGTSYRVST
.| .|  | ..  ||.|  | | .   ..|| ||   |.|.....   ..|||||. .. .          ...     |    |   .||    .. .|
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KGDVYSYGVVLLELLT-GVAPSSECLR--VRGQTLREWILDEGREDLCQV-LDPALALVDTDHGVE-IQNLVQVGLLCTAYNPSQRPSIKDVVAML
| ||.|.||.. |..| |  | ..     .  | ..|.. . .| .  .  . | ..       |.  . . |. . | ...|..||. ....  .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF------VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRR10_a.AA Pkinase_Tyr 673-872 27 6.9e-19 64.6 Pfam 1-214 (270) Show / Hide 
Range on Protein: 673-872
Range on HMM: 1-214/270
Sequence Identity: 27% (60 aa)

FSEANLLGAGGFSKVYKGTNA----LNGETVAVKVL--SSSCVD--LKSFVSEVNMLDVL-KHRNLVKVLGYCW-TWEV--KALVLEFMPNGSLASFAAR
 .    ||.| | .|||||       .. .||||.|  ...  .  ...| .|....  | .| |.|. .| |    |     .|.|.||.|.| ..  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N---SHRLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLV-HGENG-ETSVSAFKGTIGYAPPEYGTSYRVSTKGD
.    ..|. |  | ..  ||.|. | ...     || ||   |.|.. ..   ..||||.... . ..   .. ..    |   .||    .. .|| |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSD

VYSYGVVLLELLT-GVAP
|.|.||.. |..| |  |
VWSFGVLMWEIFTYGEQP
Kinase LRR10_a.AA TK 923-943 28 8.5e-05 11.17 In-house 466-486 (486) Show / Hide 
Range on Protein: 923-943
Range on HMM: 466-486/486
Sequence Identity: 28% (6 aa)

LLCTAYNPSQRPSIKDVVAML
. | .|.|..||. .... .|
QQCWHYDPEDRPTFSQLHEQL
Kinase LRR10_a.AA DRK 925-945 33 0.000498 9.58 In-house 238-258 (258) Show / Hide 
Range on Protein: 925-945
Range on HMM: 238-258/258
Sequence Identity: 33% (7 aa)

CTAYNPSQRPSIKDVVAMLEQ
|   .|..|||  ...  || 
CWNEDPQHRPSMQECLERLEA
Kinase LRR10_a.AA Dicty4 929-945 31 0.009643 5.17 In-house 259-277 (277) Show / Hide 
Range on Protein: 929-945
Range on HMM: 259-277/277
Sequence Identity: 31% (6 aa)

NPSQRPSIKDVVAM--LEQ
.|..||| . ..    || 
DPQHRPSFEEIIQRRILEH
Kinase LRR10_a.AA LRRK 924-945 31 0.010555 5.37 In-house 330-351 (351) Show / Hide 
Range on Protein: 924-945
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

LCTAYNPSQRPSIKDVVAMLEQ
.| . .| .||.  ..|  |.|
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR10_a.AA TKL-Unique 925-943 42 0.020963 4.51 In-house 272-290 (290) Show / Hide 
Range on Protein: 925-943
Range on HMM: 272-290/290
Sequence Identity: 42% (8 aa)

CTAYNPSQRPSIKDVVAML
| . .||||||  ...  |
CWHHDPSQRPSFDEIIHRL
Kinase LRR10_a.AA Pkinase_Tyr 923-943 28 0.052441 7.42 Pfam 250-270 (270) Show / Hide 
Range on Protein: 923-943
Range on HMM: 250-270/270
Sequence Identity: 28% (6 aa)

LLCTAYNPSQRPSIKDVVAML
..| .|.|..||. .... .|
KQCWHYDPEDRPTFSEIHEQL
Kinase LRR10_a.AA Pkinase 927-943 15 9.767259 0.15 Pfam 275-293 (293) Show / Hide 
Range on Protein: 927-943
Range on HMM: 275-293/293
Sequence Identity: 15% (3 aa)

AYNPSQRPSIKDVVAM--L
...|..||......    .
CKDPKKRPTAEQILQHPWF