Gene LRR10_e (S.moellendorffii)

LRR10_e

Species: S.moellendorffii
Alias: LRR10_e
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR10

Sequence

Name Sequence Type Origin Length Description Download
LRR10_e.AA Protein None 947 None Fasta, JSON
LRR10_e.NA RNA None 2844 None Fasta, JSON
LRR10_e.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of LRR10_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR10_e.AA LRRNT_2 29-69 39 3.3e-12 42.57 Pfam 4-46 (46) Show / Hide 
Range on Protein: 29-69
Range on HMM: 4-46/46
Sequence Identity: 39% (17 aa)

EADALLEFKRSVVP-SGGGGALADWSAGS-RQLVCNWTGITCD
...|||.|| |... ....|.|..|.. |     |.|||.|||
DGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR10_e.AA LRR_1 71-93 37 1.491739 6.13 Pfam 1-26 (26) Show / Hide 
Range on Protein: 71-93
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

GLVFLNLSA-N--LLRGALPPS-LELC
 |  |.||  |   | | .||| .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 96-118 44 0.011077 13.68 Pfam 1-26 (26) Show / Hide 
Range on Protein: 96-118
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

SIATLDLSS-N--GLGGAIPPS-LGNC
.. .||||. |   | | |||| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 120-142 55 9.4e-05 21.02 Pfam 1-26 (26) Show / Hide 
Range on Protein: 120-142
Range on HMM: 1-26/26
Sequence Identity: 55% (15 aa)

GLQELDLSH-N--NLTGGLPAS-MANL
 ||.||||. |  |||| .| |   ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 144-166 33 15.243927 2.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 144-166
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLATFAAEE-N--NLTGEIPSF-IGEL
.| .      |  ||||.||.  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 168-190 44 0.010448 13.77 Pfam 1-26 (26) Show / Hide 
Range on Protein: 168-190
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

ELQLLNLIG-N--SFSGGIPPS-LANC
 || |.| | |  ...| |||| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 192-214 44 0.004856 14.95 Pfam 1-26 (26) Show / Hide 
Range on Protein: 192-214
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

RLQFLFLFR-N--AITGEIPPS-LGRL
.|| | | . |   .||.|||| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 216-238 40 0.001218 17.08 Pfam 1-26 (26) Show / Hide 
Range on Protein: 216-238
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLKTLGLDN-N--FLSGPIPPS-LANC
.|..| |.. |   |.| |||| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 240-262 25 1.121006 6.57 Pfam 1-26 (26) Show / Hide 
Range on Protein: 240-262
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SLSRILLYY-N--NITGEVPLE-IARI
.| .. | . |  |.||..| . .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 264-287 33 0.658195 7.39 Pfam 1-26 (26) Show / Hide 
Range on Protein: 264-287
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

GLFTLELTG-N--QLTGSLEDFPVGHL
 | .| | | |  .|||.. .    .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 289-311 29 21.08645 2.05 Pfam 1-26 (26) Show / Hide 
Range on Protein: 289-311
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

NLTYVSFAA-N--AFRGGIPGS-ITNC
||.. ..   |   . | || | . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 313-335 29 0.004376 15.11 Pfam 1-26 (26) Show / Hide 
Range on Protein: 313-335
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

KLINMDFSR-N--SFSGEIPHD-LGRL
.|   |.|. |  ...|.||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 337-359 37 0.002271 16.12 Pfam 1-26 (26) Show / Hide 
Range on Protein: 337-359
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLRSLRLHD-N--QLTGGVPPE-IGSL
.|..| | . |  .||| .||. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 363-385 25 0.463515 7.93 Pfam 1-26 (26) Show / Hide 
Range on Protein: 363-385
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SFQGLFLQR-N--KLEGVLPAE-ISSC
. | | |.. |  .|.| .| . . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 387-409 40 0.000581 18.22 Pfam 1-26 (26) Show / Hide 
Range on Protein: 387-409
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLVEMDLSG-N--LLSGSIPRE-LCGL
.| . |||| |   |.|.|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 411-433 37 0.009728 13.88 Pfam 1-26 (26) Show / Hide 
Range on Protein: 411-433
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLEHMNLSR-N--SLGGTIPEE-IGIM
||.| .||. |  .| |.||.. .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 435-457 33 0.009728 13.88 Pfam 1-26 (26) Show / Hide 
Range on Protein: 435-457
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

MVEKINLSG-N--NLSGGIPRG-ISKC
  ....||| |  ||.| || . . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 459-481 40 0.001076 17.27 Pfam 1-26 (26) Show / Hide 
Range on Protein: 459-481
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

QLDTLDLSS-N--ELSGLIPDE-LGQL
.| .||||. |   |.| ||.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 506-524 47 0.014177 13.3 Pfam 5-26 (26) Show / Hide 
Range on Protein: 506-524
Range on HMM: 5-26/26
Sequence Identity: 47% (11 aa)

LDLSN-N--RLTGKIPVF-LAKL
||||. |  .|||.||   . .|
LDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_e.AA LRR_1 526-547 44 2.2e-05 23.26 Pfam 1-26 (26) Show / Hide 
Range on Protein: 526-547
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

KLEHLNLSS-N--NFSGEIPS--FANI
.|.||.||. |  |..|.||.  | | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR10_e.AA TKL 655-845 21 1.2e-47 164.63 In-house 1-285 (364) Show / Hide 
Range on Protein: 655-845
Range on HMM: 1-285/364
Sequence Identity: 21% (62 aa)

LGVTATSTVYKATLLD---------GSAAAVKRFKDLLSDSISS-------------------------NLFTKELRIILSIRHRNLVKTLG--------
.|  . ..|||...           |   |||.||   .|. ..                           . .|.......|| |.|. .|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-YCRN-------RSLVLDFMPNGSLEMQLHKTPCKLTWAMRLDIALGTAQALAYLHESCD-----PPVVHCDLKPSNILLDADYE--------------A
 .| .         .| ...|.|||. .||       |  |...||..|....||| .       ||..|.|||..|||.| ...              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

HVADFGISKLLETSEE---------------IASVSLMLRG-TLGYIPPEY--------GYA--------SKPSVRGDVYSFGVILLELITG
 ..|||.|. ...|..                 .  .| .. |... .||          ..        .. | . ||||||..| |..|.
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTR
Kinase LRR10_e.AA IRAK 649-847 31 2.6e-39 136.93 In-house 1-223 (317) Show / Hide 
Range on Protein: 649-847
Range on HMM: 1-223/317
Sequence Identity: 31% (71 aa)

YAAQNILGVTATSTVYKATLLDGSA--AAVKRFK---DLLSDSISSNLFT--KELRIILSIRHRNLVKTLGYCRNR---SLVLDFMPNGSLEMQLH--KT
... | .|  .  .||..  ... .   |||..|   |.  ...   . .  .||.. ...|| |.|  .|||  |   .|| ..||||||| .|.  ..
FHKDNRIGEGGFGCVYRGQ-WKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDG

PCK---LTWAMRLDIALGTAQALAYLHESC-DPPVVHCDLKPSNILLDADYEAHVADFGISKLL-ETSEEIASVS-----LMLRGTLGYIPPEYGY--AS
 |    |.| .|..|..||| .. .||.     |. | | |..|||||.. ..  .|||      ..|.  ....       .|||. | |||. .    
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

KPSVRGDVYSFGVILLELITGL-A
. ... ||||||. |||..||. |
QLTKKTDVYSFGIVLLEVLTGCRA
Kinase LRR10_e.AA TKL-Unique 651-845 29 1.2e-36 126.82 In-house 1-224 (290) Show / Hide 
Range on Protein: 651-845
Range on HMM: 1-224/290
Sequence Identity: 29% (66 aa)

AQNILGVTATSTVYKATLLDGSAAAVKRFKDLLSDSISS--NLFTKELRIILSIR-HRNLVKTLGYCR-------NRSLVLDFMPNGSLEMQLH------
  | .|  . ..||| .   |.  |.|.|.  ..|| ..    | .|....  .. | |.|.  |||        |...|....| |||   ||      
FWNKIGEGGYGQVYK-GKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---KTPCKLTWAMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNILLDAD-----YEAHVADFGISKLLETS-EEIASVS-----LMLRGTLGYIPPEY
   .  |||....|...|.  ||.. ||| .|.||. |.|||.||.|.| .     . . ..|||.||.. .. ..... .         |.. ...|| 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLH-HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

GYA--SKPSVRGDVYSFGVILLELITG
     .. |   ||||||..| |..|.
LRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase LRR10_e.AA RIPK 655-848 26 3.1e-33 110.59 In-house 1-227 (290) Show / Hide 
Range on Protein: 655-848
Range on HMM: 1-227/290
Sequence Identity: 26% (61 aa)

LGVTATSTVYKATLLDGSAAAVKRFKDLLS-----DSISSNLFTKELRIILSIRHRNLVKTLGYCRNR---------SLVLDFMPNGSLEMQLHKTPCK-
.|  . ..|.||.  .    ..|  |  .      |.  ..    |  .  ..|... |. .| |.           ..|  .|.||||.  ||  . . 
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

---LTWAMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNILLDADYEAHVADFGISKLLETS----EEI-----ASVSLMLR-GTLGYIPPEYGY--AS
   . |  |  .   .. .  ||| | .||. | ||||.|||.|... . .|||| .. ...|    ..       |    .| ||| |.|||      .
HHPDPWPLRCRMIHEISCGMCYLH-SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

KP----SVRGDVYSFGVILLELITGLAP
||    .   |||||.... |. |.  |
KPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LRR10_e.AA Pkinase 649-848 22 2e-32 115.74 Pfam 1-211 (293) Show / Hide 
Range on Protein: 649-848
Range on HMM: 1-211/293
Sequence Identity: 22% (48 aa)

YAAQNILGVTATSTVYKATLLDGSA-AAVKRFKDLLSDSISSNLFTK--ELRIILSIRHRNLVKTLGYCR---NRSLVLDFMPNG----SLEMQLH-KTP
|    ..|  . ..|||..  . .   |||..|    .|      ..  |..| ....| | |.......   .  .|......|    .|   .. .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

CKL--TWAMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNILLDADYEA----HVADFGISKLLETSEEIASVSLMLRGTLGYIPPEY-GYASKPSVRG
...  ..    .... ....|.|.|.     ..|.||||.|||.| ...     ...|||..|...  .   |    . ||..|..||    ... . . 
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGVILLELITGLAP
|..|.|.|| |...|  |
DMWSCGCILYEMLCGRPP
Kinase LRR10_e.AA LRRK 649-793 21 3.4e-28 96.84 In-house 1-225 (351) Show / Hide 
Range on Protein: 649-793
Range on HMM: 1-225/351
Sequence Identity: 21% (49 aa)

YAAQNILGVTATS-TVYKATLLD---------------------------GSAAAVKRFKD-------------------------------LLSDSISS
   .. .|. ..  .||.|.. .                           .. .|.| ..                                ...|.. .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-NLFTKELRIILSIRHRNLVKTLGYCRN-RSLVLDFMPNGSLEMQLH---KTP-----CKLTWAMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNILL
 ..| .|. |. . .| |.|. .|.| . . .|....|.|.|   ||   ...      ...| ..| |||  | ...||| |..||..|.|||. ||||
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNILL

---D---------ADYEAHVADFGIS
   .         |.. |..||||||
WSSPQNHSPNYPNAHVCAKIADFGIS
Kinase LRR10_e.AA STE 649-848 19 1.5e-22 76.52 In-house 1-267 (359) Show / Hide 
Range on Protein: 649-848
Range on HMM: 1-267/359
Sequence Identity: 19% (53 aa)

YAAQNILGVTATSTVYKATLLD----------------GSAAAVKRFK---------------DLLSDSISSNLFTKELRIILSIR--HRNLVKTLGYCR
.  . ..|  |. |||||   .                |   |.|. .               .  ...   . . ||..|    .  | | || .|.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

----------NRSLVLDFMPNGSLEMQLH---KTPCKLT----------WAMRLDIALGTAQA-LAYLHESCDPPVVHCDLKPSNILLDADYEAHVADFG
          .  ... .|..|||.  ..   .... |.                |.  . .. |.|||.     ..| |.||.||||     .  .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

ISKLLETS-------------EEIASVSLMLRGTLGYIPPEYGYA------SKPSVRGDVYSFGVILLELITGLAP
... |. |             | ... .  . ||  .  ||          .. ... |..|.|  ..|..||  |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase LRR10_e.AA MLK 649-845 23 1.4e-21 71.72 In-house 1-232 (291) Show / Hide 
Range on Protein: 649-845
Range on HMM: 1-232/291
Sequence Identity: 23% (55 aa)

YAAQNILGVTATSTVYKATLLDGSA-----AAVKRFK-DLLSDSIS----SNLFTKELRIILSIRHRN----LVKTLGYCRNR-S---LVLDFMPNGSLE
   . ..|. .   |.|..   .        ||||.. .   |. .    .  | .| |.   ..|.|     .. .| | .  .   .|. ....||| 
IQFHEWIGSGSFGKVWKGR-WRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

MQLHK-TP------------CKLTWAMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNILLDA------DYEAHVADFGISKLLETSEE-IASVSLMLR
  ||  ..               . .  ...||  |....|||.   .|..| |||..|||.|.      .  . ..|||.|. . ....   |     .
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMS----NA

GTLGYIPPEY---GYASKPSVRGDVYSFGVILLELITG
||. .  ||      ..| |   ||.|.||.| |..|.
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTR
Kinase LRR10_e.AA S_TKc 649-904 20 4.2e-21 77.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 649-904
Range on HMM: 1-231/231
Sequence Identity: 20% (54 aa)

YAAQNILGVTATSTVYKATLLD-GSAAAVKRFKDLLSDSISSNLFTKELRIILSIRHRNLVKTLGYCR--NRSLVLDFMPN--GSLEMQLHKTPCK----
|   ...|  | ..|||..  . |   |.|. |         . . .|..|  . .| |.|| .....  .  .|......  |.|   ..| ...    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTWAMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNILLDADYEAHVADFGISKLLETSEEIASVSLMLRGTLGYIPPEYGYASKPSV-RGDVYSFGV
 ..  .   ..  ...||.|.|.     ..|.||||.|||||   .  ..|||....|            . ||. |..||     . .  . |..|.|.
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

ILLELITGLAPTNSLFHGGTIQGWVSSCWPDEFGAVVDRSMGLTKDNWMEVEQAINLGLLCSSHSYM
|| |...|  |     .  ...  .    ..|.   ... .    .. . . .| . ...  .| ..
ILYEMLCGYPPFP--QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR10_e.AA Dicty4-Unclassified 692-845 33 2.7e-20 66.18 In-house 45-204 (263) Show / Hide 
Range on Protein: 692-845
Range on HMM: 45-204/263
Sequence Identity: 33% (56 aa)

FTKELRIILSIRHRNLVKTLGYCRNR-------SLVLDFMPNGSLEMQLH------KTPCKLTWAMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNIL
| ||  |  || | ||||  ||| |          |  ||. | |    |      . | ||   . . .|.  || ...|| . .  ..| |.| ||||
FKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLH-TRN--FIHRDIKSSNIL

LDADYEAHVADFGISKLLETSEEIASVSLMLRGTLGYIPPEYGYASKPSVRGDVYSFGVILLELITG
.| .. . .||||||   .       .     ||     ||         . ||||....| ||.||
MDKHFNIKIADFGISRVIDFNFNMTTIA----GTPKWESPECLMHESYNQKSDVYSYAMMLYELATG
Kinase LRR10_e.AA Dicty4 649-794 28 3.5e-20 64.16 In-house 1-162 (277) Show / Hide 
Range on Protein: 649-794
Range on HMM: 1-162/277
Sequence Identity: 28% (47 aa)

YAAQNILGVTATSTVYKATLLDGSAAAVKRF---KDLL-SDSISSNLFTKELRIILSIRHRNLVKTLGYCR----NR---SLVLDFMPNGSLEMQLHK--
.. ....|  . ..|||.|   |.. ||| .   .. . .. ...  | ||  |  .||| |... .|.|     .    . |  .|| |.|.  ||.  
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNE--FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKP

----TPCKLTWAMRLD---IALGTAQALAYLHESCDPPVVHCDLKPSNILLDADYEAHVADFGISK
       || |  ..    .|. .|. ...|| .|.| ..| |||..|.| |... . |.|||.|.
SEQQQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQ
Kinase LRR10_e.AA LISK 654-797 25 5.2e-18 54.92 In-house 1-156 (296) Show / Hide 
Range on Protein: 654-797
Range on HMM: 1-156/296
Sequence Identity: 25% (40 aa)

ILGVTATSTVYKATLL-DGSAAAVKRFK---DLLSDSISSNLFTKELRIILSIRHRNLVKTLGYCRN-RS---LVLDFMPNGSLEMQLHKTPC---KLTW
..|  . . ||| |.. .|.  |.|  .   . . |      . .|. .. ..||.| |.  | |..  .   .|  ..  | |.  |....     |.|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

AMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNILLD----ADYEAHVADFGISKLLE
  |..|||. |....|||. .   ..| |||  |.|..     .... |.|||  ....
PQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMD
Kinase LRR10_e.AA Pkinase_Tyr 662-809 22 8.9e-14 47.28 Pfam 14-176 (270) Show / Hide 
Range on Protein: 662-809
Range on HMM: 14-176/270
Sequence Identity: 22% (38 aa)

TVYKATLL-----DGSAAAVKRFKDLLSDSIS--SNLFTKELRIILSI-RHRNLVKTLGYCR----N--RSLVLDFMPNGSLEMQLHKT---PCKLTWAM
.|||.|.      ..   |||  |.  ...    .  | .|..|  .. .| |.|. .| |          .|. .||.|.|   |.|    . .||  .
EVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

RLDIALGTAQALAYLHESCDPPVVHCDLKPSNILLDADYEAHVADFGISKLL-ETSEE-IASVSLML
 |....  |....||..      .| ||   |.|.. .  . ..||| .... ....   .. . .|
LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKL
Kinase LRR10_e.AA TyrKc 649-877 20 6.5e-13 -13.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 649-877
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

YAAQNILGVTATSTVYKATLLDGSAAAVKRFKDLLSDSISSNLFTKELRIILSI--RHRNLVKTLGYCRNR----------SLVLDFMPNGSLEMQLHKT
     .||  |  .|||.|.      |||  |.          | .|.||  ..  .| |.|. .|.|.             .|. .||.|.|   |.|.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

PCKLTWAMRLDIALGTAQALAYLHESCDPPVVHCDLKPSNILLDADYEAHVADFGISKLLETS------EEIASVSL--MLR--GTLGYIPPEYGYASKP
  ||...  |....  |.  .|||.    ...| ||   |.|..... . ..||| |. ..        ..  ...     .    .   .||    .| 
RPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SVRGDVYSFGVILLELITG-----LA-----PTNSLFHGGTIQG--------W---------------VSSCWPD------EFGAVVDRS
.   ||.|||| . |. |              .|.  .    ||                         ..||         | ..... 
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRR10_e.AA LISK 831-850 45 8e-06 14.68 In-house 221-240 (296) Show / Hide 
Range on Protein: 831-850
Range on HMM: 221-240/296
Sequence Identity: 45% (9 aa)

DVYSFGVILLELITGLAPTN
||.|||..|.|.||.  ...
DVFSFGIVLCEIITRVKADP
Kinase LRR10_e.AA Dicty4 831-848 55 0.000148 11.31 In-house 199-216 (277) Show / Hide 
Range on Protein: 831-848
Range on HMM: 199-216/277
Sequence Identity: 55% (10 aa)

DVYSFGVILLELITGLAP
|||||| .| |. |. .|
DVYSFGIVLWEILTRQEP
Kinase LRR10_e.AA LRRK 831-848 57 0.000294 10.95 In-house 264-282 (351) Show / Hide 
Range on Protein: 831-848
Range on HMM: 264-282/351
Sequence Identity: 57% (11 aa)

DVYSFGVILLELITGL-AP
|.||||.|| ||.|..  |
DCYSFGMILWELLTRQHHP