Gene LRR10_b (S.moellendorffii)

LRR10_b

Species: S.moellendorffii
Alias: LRR10_b
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR10

Sequence

Name Sequence Type Origin Length Description Download
LRR10_b.AA Protein None 908 None Fasta, JSON
LRR10_b.NA RNA None 2727 None Fasta, JSON
LRR10_b.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of LRR10_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 LRR10_b.AA LRR_1 43-65 29 2.289896 5.47 Pfam 1-26 (26) Show / Hide 
Range on Protein: 43-65
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RVRALNLSR-L--GLEGVISPQ-IAAL
. . |.||.     |.| |.|  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 67-89 40 0.00035 19.0 Pfam 1-26 (26) Show / Hide 
Range on Protein: 67-89
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

HLAVLDLQT-N--NLSGSIPSE-LGNC
.| .|||.  |  ||.|.||.. . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 91-113 48 0.014363 13.28 Pfam 1-26 (26) Show / Hide 
Range on Protein: 91-113
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

SLQGLFLAS-N--LLTGAIPHS-LGNL
.|| | | . |   ||| ||.| . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 115-137 40 0.022192 12.61 Pfam 1-26 (26) Show / Hide 
Range on Protein: 115-137
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLRGLHLHE-N--LLHGSIPPS-LGNC
.|. |.|   |   | |.|||| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 139-161 37 0.399208 8.16 Pfam 1-26 (26) Show / Hide 
Range on Protein: 139-161
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

LLTDLELAK-N--GLTGRIPEA-LGRL
 |. | |   |   ||| ||.  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 163-185 40 0.006895 14.41 Pfam 1-26 (26) Show / Hide 
Range on Protein: 163-185
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

MLQSLYLFE-N--RLTGRIPEQ-IGGL
 ||.|.|   |  .||| ||.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 187-209 44 0.000205 19.82 Pfam 1-26 (26) Show / Hide 
Range on Protein: 187-209
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

RLEELILYS-N--KLSGSIPPS-FGQL
.|..| | . |  .|.|.|||| | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 211-233 37 0.007077 14.37 Pfam 1-26 (26) Show / Hide 
Range on Protein: 211-233
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLRLLYLYA-N--ELEGSIPPV-LSNC
.|. |.|   |   |.|.|||  . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 235-257 37 0.003745 15.35 Pfam 1-26 (26) Show / Hide 
Range on Protein: 235-257
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLEDVELSQ-N--RLTGSIPTE-LGSL
.|.   ||  |  .|||.|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 259-281 33 0.054727 11.22 Pfam 1-26 (26) Show / Hide 
Range on Protein: 259-281
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

KLAFLSIFE-T--NLTGSIPDE-LGHL
.|  |..   .  ||||.||.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 283-305 37 0.005529 14.75 Pfam 1-26 (26) Show / Hide 
Range on Protein: 283-305
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

ELTELLLYS-N--RLTGSLPQS-LGRL
 |..| | . |  .|||..| | .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 307-329 40 0.000253 19.5 Pfam 1-26 (26) Show / Hide 
Range on Protein: 307-329
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLTTLFLYD-N--NLTGELPAS-LGNC
.|..| | . |  ||||..| | . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 331-353 33 27.157073 1.66 Pfam 1-26 (26) Show / Hide 
Range on Protein: 331-353
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

LLVDVELQM-N--NFSGGLPPS-LAFL
 |    |.  |  |..| .||| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 355-377 25 0.45163 7.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 355-377
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

ELQVFRIMS-N--RLSGPFPSA-LTNC
 ||.  . . |  .|.| .|.  . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 379-401 29 0.000366 18.93 Pfam 1-26 (26) Show / Hide 
Range on Protein: 379-401
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

QLKVLDLGD-N--HFSGKVPEE-IGSL
.|..|||.. |  ...|..|.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 403-425 37 0.039298 11.73 Pfam 1-26 (26) Show / Hide 
Range on Protein: 403-425
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLQQLQLYE-N--EFSGPIPSS-LGTL
.|| | |   |   ..| ||.| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 427-449 44 0.002553 15.94 Pfam 1-26 (26) Show / Hide 
Range on Protein: 427-449
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

ELYHLAMSY-N--RLSGSIPDS-FASL
 | || .|. |  .|.|.||.| | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 451-474 29 0.066068 10.93 Pfam 1-26 (26) Show / Hide 
Range on Protein: 451-474
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SIQGIYLHG-N--YLSGEVPFAALRRL
..| ..| | |   |.|..|  ..  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 487-509 51 6.2e-05 21.67 Pfam 1-26 (26) Show / Hide 
Range on Protein: 487-509
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

SLVTLDLSS-N--NLTGRIPKS-LATL
.| .||||. |  |||| ||.| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10_b.AA LRR_1 511-535 35 0.510937 7.78 Pfam 1-26 (26) Show / Hide 
Range on Protein: 511-535
Range on HMM: 1-26/26
Sequence Identity: 35% (10 aa)

GLSSLNVSM-N--NLQGPVPQEGVFLKL
 | .|..|  |  ||.| .| .  | .|
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
Kinase LRR10_b.AA TKL 639-903 20 1.2e-51 177.9 In-house 1-364 (364) Show / Hide 
Range on Protein: 639-903
Range on HMM: 1-364/364
Sequence Identity: 20% (79 aa)

LGAGGFSKVYKGTNALNG--------ETVAVKVLSS----------------------------SCADLKSFVSEVNMLDVLKHRNLVKVLGYCWTWEV-
.| |||..||||.   .|        ..||||...|                            ..   . .. |..|.  |.| |.|. .|||   .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KALVLEFMPNGSLASFAARNSHRLDWKIRLTIAEGIAQGLYYMHNQL-----KDPVIHCDLKPGNVLLDAGLS--------------P
             ..| |..|.||| ..         |  |. .| .||.|..|.|..      | |.||.|||. |.|.|  .               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

HVADFGLSKLVHGE-----------------NGETSVSAFKGTIGYAPPEY----------------GTSYRVSTKGDVYSYGVVLLELLTGVAPSS--E
 ..|||||. ....                 |...  .   ||... .||                   ..  |.| ||||.|.|| |.||.  | .   
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

CLRVRGQ----TLREWILDEGREDLCQ-----VLDPALALVDTDHGVEIRNLVQVGLLCTAYNPSQRPSIKDVVAML
.  . .|       ... |.|.  ..      ..      .  .     . . .    | ...|..||| ....  |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH----K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR10_b.AA IRAK 633-829 33 3.8e-46 159.62 In-house 1-220 (317) Show / Hide 
Range on Protein: 633-829
Range on HMM: 1-220/317
Sequence Identity: 33% (74 aa)

FSEANLLGAGGFSKVYKGTNALNGET--VAVK----VLSSSCADLK-SFVS---EVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPNGSL-ASFAARN
|...|..| |||  ||.|   ....|  .|||    . ..|.  .. .| .   |.  .  . | |.| ..|||   .   || ..|||||| .  ....
FHKDNRIGEGGFGCVYRG--QWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQD

-SHR---LDWKIRLTIAEGIAQGLYYMHNQL-KDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLV----HGENGET---SVSAFKGTIGYAPPEYGT--S
 .     | | .|. |..|.| |... |.   . |.|| | |. |.|||. . |  .||||        | | ..     .| ..||  | |||. .  .
GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQ

YRVSTKGDVYSYGVVLLELLTG
 . ..| |||| |.||||.|||
GQLTKKTDVYSFGIVLLEVLTG
Kinase LRR10_b.AA TKL-Unique 636-836 30 2.6e-44 153.54 In-house 2-237 (290) Show / Hide 
Range on Protein: 636-836
Range on HMM: 2-237/290
Sequence Identity: 30% (72 aa)

ANLLGAGGFSKVYKGTNALNGETVAVKVLSS---SCADLKS-FVSEVNMLDVLK-HRNLVKVLGYCW--TWEVK--ALVLEFMPNGSLASFAA-------
 |..|.||...||||.   .|. ||.|...    |  ...  | .||| . .|. | |.|.  |||   .   .   .|.|..| ||| .  .       
WNKIGEGGYGQVYKGK--WRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--RNSHRLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAG-----LSPHVADFGLSKLVHGENGETSV-------SAFKGTIGYAPPEYG
  .|.. |... |...|. ||||.|| |.  .  .||.|||. |.|.| .     ..  ..||||||.   .| .|.        . ..|.. ...||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

TS--YRVSTKGDVYSYGVVLLELLTGVA------PSSEC
..  .  |.| ||||.|.|| |..|.        | ...
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGM
Kinase LRR10_b.AA Pkinase 633-832 24 1.5e-42 151.54 Pfam 1-211 (293) Show / Hide 
Range on Protein: 633-832
Range on HMM: 1-211/293
Sequence Identity: 24% (54 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCADLKSFVS-----EVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPNG----SLASFAA-RNS
.     .|.|.|..|||...  .|..||||... . .. .  ..     |. ..  |.| | |. .... .     .|.|....|    .|...   ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HRL--DWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSP----HVADFGLSKLVHGENGETSVSAFKGTIGYAPPEY-GTSYRVSTKGD
 ..  ...    ..  |..||.|.|..    .||.|||| |.|.|    .    ...||||.|..  .   .  . | ||..|..||   ..   ..| |
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSYGVVLLELLTGVAP
..|.|..| |.|.|  |
MWSCGCILYEMLCGRPP
Kinase LRR10_b.AA RIPK 639-832 27 9.1e-38 126.27 In-house 1-227 (290) Show / Hide 
Range on Protein: 639-832
Range on HMM: 1-227/290
Sequence Identity: 27% (64 aa)

LGAGGFSKVYKGTNALNGETVAVKVLSSSCAD-------LKSFVSEVNMLDVLKHRNLVKVLGYCWTWEV------KALVLEFMPNGSLASFAARNS---
.| |||..|.| . .  |. ||.|.  .   .        .    |. ..  |.... |...| |   |        ..| |.|.||||. | .. .   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-HRLDWKIRLTIAEGIAQGLYYMHNQLKD-PVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGE--NG--------ETSVSAFK-GTIGYAPPEYGT---
 | . |. |  .   |. |  | |.  .. |.|| ||||.|.|.|. .   .|||||..   .   ..          . |... ||. | |||      
HHPDPWPLRCRMIHEISCGMCYLHS--MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

SYR---VSTKGDVYSYGVVLLELLTGVAP
. .   |..| ||||...|. |.||.  |
KKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LRR10_b.AA S_TKc 633-906 21 6.9e-36 126.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 633-906
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCADLKSFVSEVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPN--GSLASFAARNSHR-----L
.   ...| |.|.||||...   |. ||.|...      ... .|...|   .| |.|| .... . .   .|.|....  |.| ..  .. ..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGENGETSVSAFKGTIGYAPPEYGTSYRVST-KGDVYSYGVVLL
.      ..  |...| |.|.. .  .||.|||| |.|||      ..||||....         . | ||  | .||       .. | |..| |..| 
PE-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELLTGVAPSSECLRVRGQTLREWILDEGREDLCQVLDPALALVDTDHGVEIRNLVQVGLLCTAYNPSQRPSIKDVVA------MLEQL
|.|.|  | .       |.. . |.                        | .....    |  ..|..||.. .. .      . . .
EMLCGYPPFP-----QMQMMFKKIG----------------------SPEAKDFIR---KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR10_b.AA MLK 633-829 27 1.2e-31 107.17 In-house 1-232 (291) Show / Hide 
Range on Protein: 633-829
Range on HMM: 1-232/291
Sequence Identity: 27% (64 aa)

FSEANLLGAGGFSKVYKGTNALNGET-----VAVKVLS-------SSCADLKSFVSEVNMLDVLKHRN----LVKVLGYCWTWEV-KALVLEFMPNGSLA
. .   .|.|.| ||.||.    ...     ||||          .. .  . |  |.. | .|.|.|     ....| |   .   ..|.|....|||.
IQFHEWIGSGSFGKVWKGR--WRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

SFA--AR-----------NSHRLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDA------GLSPHVADFGLSKLVHGENGETSVSAFKGT
..   ||           |. . |    ...|  .|.|. | |.....|.|| |||. |.|.|.      ..   ..|||.|. .| ... |    ..||
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWH-QMC-TNMMSNAGT

IGYAPPEY---GTSYRVSTKGDVYSYGVVLLELLTG
  .  ||      . ..| | ||.|.|||| |.||.
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTR
Kinase LRR10_b.AA LRRK 633-829 22 3.2e-28 96.95 In-house 1-278 (351) Show / Hide 
Range on Protein: 633-829
Range on HMM: 1-278/351
Sequence Identity: 22% (66 aa)

FSEANLLGAGGFS-KVYKGTNALN--------------------------GETVAVKVLSS-----------------------------------SCAD
. . ...| |||  .||...   .                          ...||.|..                                     .|  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LKSFVSEVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPNGSLASFAARNS-HR-------LDWKIRLTIAEGIAQGLYYMHNQLKD-PVIHCDLKPGN
. .|  || ..  |.| |.|. .|.|   .  ..|.|..|.|.| .|   .. ..       ..| ..| ||  || |. |.|.  .. |.||.|||. |
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS--HNPPIIHRDLKSPN

VLL---D---------AGLSPHVADFGLSK---LVHGENGETSVSAFKGTIGYAPPEYGT-----SYRVSTKGDVYSYGVVLLELLTG
.||   .         |    ..||||.|     .| .   ..|    |..|.  ||        .|  ..| |.||.|..| ||||.
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV----GNPGWMAPEIMRYNGEEEY--TEKVDCYSFGMILWELLTR
Kinase LRR10_b.AA TK 633-828 15 8.4e-28 89.65 In-house 1-389 (486) Show / Hide 
Range on Protein: 633-828
Range on HMM: 1-389/486
Sequence Identity: 15% (61 aa)

FSEANLLGAGGFS---KVYKGTNALNG-------------------------ETVAVKVLSSSCADLKS------------------FVSEVNMLD--VL
    . ||.| |    .||||.    .                         ..||||.| . .|. .                   ...|  |..  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KHRNLVKVLGYCWTWEVK------------ALVLEFMPNGS----LASFAARNS----------------------------------------------
.| |.|. .|.|   | |             .|.|.||.|.    | ..  ...                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------------------------HRLDWKIRLTIAEGIAQGLYYMHNQ----LKDPVIHCDLKPGNVLLDAGLS-----------PHVADFGLS
                             |.|. . .| ..  ||.|. |.| .        ..| ||   |.|.. ..              .||||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-------LVHGENGETSVSAFKGTIG-------------------------YAPPEYGT---------SYRVSTKGDVYSYGVVLLELLT
.         ......  ..  .|| .                         . .||  .           . .|| ||.|.||.. |..|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase LRR10_b.AA Abl 633-832 30 4.8e-26 83.47 In-house 1-198 (252) Show / Hide 
Range on Protein: 633-832
Range on HMM: 1-198/252
Sequence Identity: 30% (62 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCADLKSFVSEVNMLDVLKHRNLVKVLGYCWTWEVKALVLEFMPNGSLASFAARNSHR-LDWKIRL
 .  . || | .  ||.|     . ||||| |     ... |. |  ..  .||.|||..|| |       .. |||..| |  .  ..... |.  . |
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

TIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGENGETSVSAFKGTIGYAPPEYGTSYRVSTKGDVYSYGVVLLELLT-GV
 .|  || |. |. ..     || ||   | |.       ||||||.......   |     |  | .  ||    .. |.| ||. .||.| |. | |.
YMATQIASGMSYLEKRH---FIHRDLAARNCLVGEHHIVKVADFGLARMMKDDT-YTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGM

AP
.|
SP
Kinase LRR10_b.AA Dicty4 633-832 31 5.7e-26 83.75 In-house 1-216 (277) Show / Hide 
Range on Protein: 633-832
Range on HMM: 1-216/277
Sequence Identity: 31% (68 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVL-----SSSCADLKSFVSEVNMLDVLKHRNLVKVLGYCW----TWEVKALVLEFMPNGSLASFAAR---
    ...| |.|..|||||    |  ||||.|      .. . |..|  ||. .  . | |... .|.|     . .    | |.|| |.|.|       
INIEQRIGKGSFGEVYKGT--WRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---NSHRLDWKIRLT---IAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSK-LVHGENGETSVSAFKGTIGYAPPEYGTSYRVSTK
    |  |||  ..    .|  .|.|. . |.   . .|| |||. | | |. .   |.|||||.    .|.  .  .. .|| ..  ||   . .   |
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEK

GDVYSYGVVLLELLTGVAP
 ||||.| || |.||. .|
ADVYSFGIVLWEILTRQEP
Kinase LRR10_b.AA Dicty4-Unclassified 636-829 32 5.8e-26 85.88 In-house 4-204 (263) Show / Hide 
Range on Protein: 636-829
Range on HMM: 4-204/263
Sequence Identity: 32% (69 aa)

ANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCADLK-----SFVSEVNMLDVLKHRNLVKVLGYCWTW----EVKALVLEFMPNGSLASFAA------R
   .| | ||||.||     |  |||| . .            |  || .|  . | ||||. |||            | |||. | |            
DQFIGKGHFSKVHKG--NWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

NSHRLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGENGETSVSAFKGTIGYAPPE--YGTSYRVSTKGDVYS
 . .||  . . .|  ||||. ..|      .|| |.|  |.|.|      .||||.|  .      | .    ||     ||   . ||    | ||||
QPIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIA---GTPKWESPECLMHESY--NQKSDVYS

YGVVLLELLTG
|...| ||.||
YAMMLYELATG
Kinase LRR10_b.AA TyrKc 633-903 23 9.9e-21 76.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 633-903
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

FSEANLLGAGGFSKVYKGTNALNGETVAVKVLSSSCADLKSFVSEVNMLDVL--KHRNLVKVLGYCWTW-------EVKALVLEFMPNGSLASFAARNSH
 .    || | | .|||||     ..||||.| ...  .. | .| ...  |  .| |.|. .|.| .        |   .|.|.||.|.| ..  .. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLVHGE------NGETSVS---AFK--GTIGYAPPEYGTSYRVST
.| .|  | ..  ||.|  | | .   ..|| ||   |.|.....   ..|||||. .. .          ...     |    |   .||    .. .|
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KGDVYSYGVVLLELLT-GVAPSSECLR--VRGQTLREWILDEGREDLCQV-LDPALALVDTDHGVEIRNLVQVGLLCT--AYNPSQRPSIKDVVAML
| ||.|.||.. |..| |  | ..     .  | ..|.. . .| .  .  . | ..       |.    .   .  .  ...|..||. ....  .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF------VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase LRR10_b.AA Pkinase_Tyr 633-832 27 3.4e-19 65.62 Pfam 1-214 (270) Show / Hide 
Range on Protein: 633-832
Range on HMM: 1-214/270
Sequence Identity: 27% (60 aa)

FSEANLLGAGGFSKVYKGTNA----LNGETVAVKVL--SSSCAD--LKSFVSEVNMLDVL-KHRNLVKVLGYCW-TWEV--KALVLEFMPNGSLASFAAR
 .    ||.| | .|||||       .. .||||.|  ...  .  ...| .|....  | .| |.|. .| |    |     .|.|.||.|.| ..  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N---SHRLDWKIRLTIAEGIAQGLYYMHNQLKDPVIHCDLKPGNVLLDAGLSPHVADFGLSKLV-HGENG-ETSVSAFKGTIGYAPPEYGTSYRVSTKGD
.    ..|. |  | ..  ||.|. | ...     || ||   |.|.. ..   ..||||.... . ..   .. ..    |   .||    .. .|| |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSD

VYSYGVVLLELLT-GVAP
|.|.||.. |..| |  |
VWSFGVLMWEIFTYGEQP
Kinase LRR10_b.AA TK 883-903 28 8.5e-05 11.17 In-house 466-486 (486) Show / Hide 
Range on Protein: 883-903
Range on HMM: 466-486/486
Sequence Identity: 28% (6 aa)

LLCTAYNPSQRPSIKDVVAML
. | .|.|..||. .... .|
QQCWHYDPEDRPTFSQLHEQL
Kinase LRR10_b.AA Dicty4 889-905 31 0.009643 5.17 In-house 259-277 (277) Show / Hide 
Range on Protein: 889-905
Range on HMM: 259-277/277
Sequence Identity: 31% (6 aa)

NPSQRPSIKDVVAM--LEQ
.|..||| . ..    || 
DPQHRPSFEEIIQRRILEH
Kinase LRR10_b.AA LRRK 884-905 31 0.010555 5.37 In-house 330-351 (351) Show / Hide 
Range on Protein: 884-905
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

LCTAYNPSQRPSIKDVVAMLEQ
.| . .| .||.  ..|  |.|
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR10_b.AA TKL-Unique 885-903 42 0.020963 4.51 In-house 272-290 (290) Show / Hide 
Range on Protein: 885-903
Range on HMM: 272-290/290
Sequence Identity: 42% (8 aa)

CTAYNPSQRPSIKDVVAML
| . .||||||  ...  |
CWHHDPSQRPSFDEIIHRL
Kinase LRR10_b.AA Pkinase_Tyr 883-903 28 0.052441 7.42 Pfam 250-270 (270) Show / Hide 
Range on Protein: 883-903
Range on HMM: 250-270/270
Sequence Identity: 28% (6 aa)

LLCTAYNPSQRPSIKDVVAML
..| .|.|..||. .... .|
KQCWHYDPEDRPTFSEIHEQL
Kinase LRR10_b.AA Pkinase 887-903 15 9.767259 0.15 Pfam 275-293 (293) Show / Hide 
Range on Protein: 887-903
Range on HMM: 275-293/293
Sequence Identity: 15% (3 aa)

AYNPSQRPSIKDVVAM--L
...|..||......    .
CKDPKKRPTAEQILQHPWF