Gene LRR10a_b-1 (S.moellendorffii)

LRR10a_b-1

Species: S.moellendorffii
Alias: LRR10a_b-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR10a

Sequence

Name Sequence Type Origin Length Description Download
LRR10a_b-1.AA Protein None 1068 None Fasta, JSON
LRR10a_b-1.NA RNA None 3207 None Fasta, JSON
LRR10a_b-1.kin_dom Protein Kinase Domain None 206 None Fasta, JSON

Protein domain

Protein domains of LRR10a_b-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR10a_b-1.AA LRRNT_2 6-40 38 8.9e-10 34.66 Pfam 8-46 (46) Show / Hide 
Range on Protein: 6-40
Range on HMM: 8-46/46
Sequence Identity: 38% (15 aa)

LLRFKRSLL--LANPSALQSWKPDD--RSPCEWQGVSCV
||.|| ||     ....|.||.|..   ..| | ||.| 
LLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR10a_b-1.AA LRR_1 43-65 33 0.03854 11.76 Pfam 1-26 (26) Show / Hide 
Range on Protein: 43-65
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

HVISIDLSN-Q--RLTGPIPDD-IGLL
.  ..|||.    .||| ||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 138-160 40 2.5e-05 23.05 Pfam 1-26 (26) Show / Hide 
Range on Protein: 138-160
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ALERLDLSG-N--QFHGSIPSS-LGGC
 |..||||| |  .. |.||.| . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 113-136 44 0.00052 18.39 Pfam 1-26 (26) Show / Hide 
Range on Protein: 113-136
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

GIQFLNISS-N--NLTGAIPPELFSQC
 .| |..|. |  |||| |||. | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 91-112 29 0.008543 14.08 Pfam 1-26 (26) Show / Hide 
Range on Protein: 91-112
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

GLRTLDISN-N--SLSGSLPR--ILSP
 |..||.|. |  .|.|..|   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 89-112 41 0.03887 11.41 SMART 1-24 (24) Show / Hide 
Range on Protein: 89-112
Range on HMM: 1-24/24
Sequence Identity: 41% (10 aa)

LGGLRTLDISNNSLSGSLPRILSP
|. ||.|| ||| |.   |.....
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 67-89 37 0.064374 10.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 67-89
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

DLESLILAA-N--SLNGSIPDV-IGNL
 |..| |   |  .| |.||.  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 136-160 32 0.33643 3.73 SMART 1-24 (24) Show / Hide 
Range on Protein: 136-160
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

CQALERLDLSGNQFHGSIPSSLGGC
  .|..||||.||.  ..|. . ..
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 162-184 33 0.095664 10.36 Pfam 1-26 (26) Show / Hide 
Range on Protein: 162-184
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ALEVLSLEN-T--NLVGEIPPE-LASG
 |..|.| . .  ||.|.|||. . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 256-279 37 0.000231 21.74 SMART 1-24 (24) Show / Hide 
Range on Protein: 256-279
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

LRSLRFLVLGRNNITELPASIANC
|..|| | |..|..|.||. . ..
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 258-279 33 0.001218 17.08 Pfam 1-26 (26) Show / Hide 
Range on Protein: 258-279
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLRFLVLGR-N--NIT-ELPAS-IANC
.|. | |.. |  |.| ..| | . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 211-234 44 0.00147 16.79 Pfam 1-26 (26) Show / Hide 
Range on Protein: 211-234
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

SLRNIDLSL-N--NLTGEIPREIFRSA
.|. .|||  |  ||||.|| ..| . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 186-210 40 0.015035 14.79 SMART 1-24 (24) Show / Hide 
Range on Protein: 186-210
Range on HMM: 1-24/24
Sequence Identity: 40% (10 aa)

LASLTDLNLANNHLVGSIPGGLFVP
| .|. |.| ||.|  ..| |.| .
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 188-207 34 0.042208 11.62 Pfam 1-26 (26) Show / Hide 
Range on Protein: 188-207
Range on HMM: 1-26/26
Sequence Identity: 34% (9 aa)

SLTDLNLAN-N--HLVGSIPG---GL
.|. |.| . |  .|.|.||    .|
NLQHLDLSGCNCCNLTGHIPPSCFNL
LRR_1 LRR10a_b-1.AA LRR_1 235-256 33 0.080279 10.63 Pfam 1-26 (26) Show / Hide 
Range on Protein: 235-256
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

DLESLFLSQ-N--HFT-RIPQE-IGLL
 |..| ||  |  ..|  || . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 234-255 30 0.537856 2.06 SMART 2-24 (24) Show / Hide 
Range on Protein: 234-255
Range on HMM: 2-24/24
Sequence Identity: 30% (7 aa)

ADLESLFLSQNHFTRIPQEI-GL
  |..| || |..|..|... . 
PNLRELDLSNNQLTHLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 281-303 33 0.299992 8.6 Pfam 1-26 (26) Show / Hide 
Range on Protein: 281-303
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ELRVLILNE-N--LLAGEIPAA-IAKL
 |..| |.  |   | |.||   . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 305-327 33 2.892906 5.11 Pfam 1-26 (26) Show / Hide 
Range on Protein: 305-327
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

KLQFLVLHT-N--GFTGGIPEW-IATS
.|| | |   |   .|| ||.. .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 330-352 44 0.001186 17.12 Pfam 1-26 (26) Show / Hide 
Range on Protein: 330-352
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

QLLHLDLSD-N--SITGVIPSG-FNAT
.| |||||. |  ..|| ||.. | . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 329-351 39 0.534843 2.08 SMART 2-24 (24) Show / Hide 
Range on Protein: 329-351
Range on HMM: 2-24/24
Sequence Identity: 39% (9 aa)

RQLLHLDLSDNSITGVIPSGFNA
..| .||||.| .| . |  |. 
PNLRELDLSNNQLTHLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 356-378 48 0.00121 17.09 Pfam 1-26 (26) Show / Hide 
Range on Protein: 356-378
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

KLQFLLLAG-N--RLTGSIPPS-LGEI
.|| | | | |  .|||.|||| .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 354-378 36 0.142787 6.78 SMART 1-24 (24) Show / Hide 
Range on Protein: 354-378
Range on HMM: 1-24/24
Sequence Identity: 36% (9 aa)

LAKLQFLLLAGNRLTGSIPPSLGEI
| .|. | | .|.|| ..|| . . 
LPNLRELDLSNNQLT-HLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 380-402 59 9.5e-07 28.1 Pfam 1-26 (26) Show / Hide 
Range on Protein: 380-402
Range on HMM: 1-26/26
Sequence Identity: 59% (16 aa)

QLQFLDLSG-N--RLTGSIPPS-LGKL
.|| ||||| |  .|||.|||| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 404-426 37 0.012945 13.44 Pfam 1-26 (26) Show / Hide 
Range on Protein: 404-426
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLLWLMLAN-N--NLSGAIPRE-LGNC
.|  | | . |  ||.| || . . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 402-426 32 0.04922 10.57 SMART 1-24 (24) Show / Hide 
Range on Protein: 402-426
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

LTRLLWLMLANNNLSGAIPRELGNC
|. |  | | ||.|  ..|... ..
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 428-450 22 1.030259 6.7 Pfam 1-26 (26) Show / Hide 
Range on Protein: 428-450
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

SLLWLNAAK-N--SIAGELPPE-LESM
.|  |.    |  .. |..||. . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 526-548 29 7.320681 3.68 Pfam 1-26 (26) Show / Hide 
Range on Protein: 526-548
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SMGYIQLSE-N--RLSGSIPAS-YGGI
.  .. ||  |  .|.|.|| |   . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 597-619 48 0.000108 20.81 Pfam 1-26 (26) Show / Hide 
Range on Protein: 597-619
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

CLQSLDLSS-N--RLSGQIPYS-LTRL
 ||.||||. |  .|.|.|| | .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 573-595 40 0.001499 16.76 Pfam 1-26 (26) Show / Hide 
Range on Protein: 573-595
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLTGLNLSH-N--ALEGAIPDS-FGQF
.|. |.||. |   |.| ||.| | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR10a_b-1.AA LRR_1 550-572 40 0.058021 11.13 Pfam 1-26 (26) Show / Hide 
Range on Protein: 550-572
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLSLLFLYQ-N--RLSGAIPGS-LSNL
.|  | |   |  .|.| || | . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR10a_b-1.AA LRR_TYP 595-619 32 0.441831 2.76 SMART 1-24 (24) Show / Hide 
Range on Protein: 595-619
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

FQCLQSLDLSSNRLSGQIPYSLTRL
   |..||||.|.|  ..|  . . 
LPNLRELDLSNNQL-THLPPGAFQG
LRR_TYP LRR10a_b-1.AA LRR_TYP 569-594 38 0.774943 0.76 SMART 1-24 (24) Show / Hide 
Range on Protein: 569-594
Range on HMM: 1-24/24
Sequence Identity: 38% (10 aa)

LSNLKLTGLNLSHNALEGAIPDSFGQ
|.||  . |.||.|.|.   |. |. 
LPNL--RELDLSNNQLTHLPPGAFQG
LRR_1 LRR10a_b-1.AA LRR_1 621-643 29 4.738499 4.35 Pfam 1-26 (26) Show / Hide 
Range on Protein: 621-643
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLNKFNVSY-N-PGLAGPIPF--AGQL
.| . ..|. | . | | ||     .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR10a_b-1.AA IRAK 791-999 38 2.7e-64 219.89 In-house 1-226 (317) Show / Hide 
Range on Protein: 791-999
Range on HMM: 1-226/317
Sequence Identity: 38% (88 aa)

FHDSNIVGCGGFGVVYKAQLSDGS-TVAIKKLIREGP----AGEREFQA---EMHTLGHIVHENLVPLMGYSSYGAQMLLVYELMVNGSVEDWLYGCRRH
|| .|  | ||||.||..|..    ..|.|||. .        ...||.   |. ..  . |.|.||| ||.. . .  |||..| ||| || |  |.  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLW-CQDG

AGGAGGLDWPARLDVAIGTARGLKFLHHSCSP-PIIHRDMKASNILLDAGFRPRVTDFGLARAL--AGQEETHVS-----TIVAGTLGYVPPEYCQ--TW
..    | |. |.....|||.|. |||   .  ||||.| | .|||||. | |  .||||.|    |.  | ...      .| ||. | |||.    . 
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

RATVKGDVYSYGVVLLELLSGRRPMLD
. |.| |||| |.||||.|.|.|...|
QLTKKTDVYSFGIVLLEVLTGCRAVYD
Kinase LRR10a_b-1.AA TKL 797-1059 21 5.6e-53 182.33 In-house 1-364 (364) Show / Hide 
Range on Protein: 797-1059
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

VGCGGFGVVYKAQLSD---------GSTVAIKKLIREGPAGERE-------------------------FQAEMHTLGHIV--HENLVPLMGYSSYGAQ-
.| ||||.|||...           | .||.||. ..    . .                         |. |  .. ..   |.|.|..|||. .. . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------MLLVYELMVNGSVEDWLYGCRRHAGGAGGLDWPARLDVAIGTARGLKFLHHSCS-----PPIIHRDMKASNILLDAGFR---------
            . .|.|.. .|| .. |              |. |.. |...|||. .|| .       ||||||| | .|||.|  ..         
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNP

-----PRVTDFGLAR-ALAGQEETHV----------------STIVAGTLGYVPPEY----------------CQTWRATVKGDVYSYGVVLLELLSGRR
     . ..||||.|     .. ..                 .  . ||... .||                 |. . .. | ||||.|.|| |.|...|
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR

PMLDAGNY------------IMAGEDSGRDL-------HHNVEEFEDQCYSNLVEWA-FLRLALDCTQDVPVRRPCMRDVCQRL
|  | ...            .|..... | .       ||     . . . .   .  . .|. || .  |  || . .. .||
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-----K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR10a_b-1.AA Pkinase 791-994 25 9.2e-38 134.61 Pfam 1-209 (293) Show / Hide 
Range on Protein: 791-994
Range on HMM: 1-209/293
Sequence Identity: 25% (56 aa)

FHDSNIVGCGGFGVVYKAQLSDGST-VAIKKLIREGPAGEREFQA-----EMHTLGHIVHENLVPLMGYSSYGAQMLLVYELMVNG----SVEDWLYGCR
.|   ..| |.||.|||..  . .  ||.|.. ..  . . . |.     | . . .. |.| | | ..  ..  . .| |.. .|    .  |.. .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

RHAGGAGGL--DWPARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRP----RVTDFGLARALAGQEETHVSTIVAGTLGYVPPEYCQ-TWR
      |..  ..    ...  ..|||...|      |||||.| .|||.|    .    ...|||||. .      .  | ..||..|..|| ..    
---WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQY

ATVKGDVYSYGVVLLELLSGR
 . | |..|.|..| |.|.||
YGPKVDMWSCGCILYEMLCGR
Kinase LRR10a_b-1.AA TK 791-1059 13 9.8e-33 106.49 In-house 1-486 (486) Show / Hide 
Range on Protein: 791-1059
Range on HMM: 1-486/486
Sequence Identity: 13% (68 aa)

FHDSNIVGCGGFG---VVYKAQLSDGS--------------------------TVAIKKLIREGPAGEREFQA--------------EMHTLGHIV----
 .  .  | | ||   .|||... ...                          .||.| |  . .. ..||..              |.. .        
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENLVPLMGYSSYGAQ------------MLLVYELMVNGS----VEDWLYGCRRHAGG-----------------------------------------
 |.|.| | |... |.             ...| |.| .|.      |.|  ||...                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------AGGLDWPARLDVAIGTARGLKFLHHS----CSPPIIHRDMKASNILLDAGFR-----------PRVTDFG--
                             . |. . .|  .   |.|. .||        . ..|||  | |.|.. . .            ...|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LARALAGQEETHVSTIVAGTLG------------------------YVPPEYCQ---------TWRATVKGDVYSYGVVLLELLS-G-RRPMLD
      |||..   .. ....   ....                        . .||  .         . . | | ||.|.||.. |... |   .  .
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

AGN----------YIMAGEDSGRDL---------HHNVEEFEDQCYS---------NLVEWAFLRLALDCTQDVPVRRPCMRDVCQRL
  |           .|    .|. |         . .  .  ..| .         .  . .. .| ..| .  | .|| .... ..|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR10a_b-1.AA MLK 791-996 25 1.3e-28 96.39 In-house 1-235 (291) Show / Hide 
Range on Protein: 791-996
Range on HMM: 1-235/291
Sequence Identity: 25% (62 aa)

FHDSNIVGCGGFGVVYKAQLSDGS----TVAIKKLI--REGPAGE-----REFQAEMHTLGHIVHEN----LVPLMGY-SSYGAQMLLVYELMVNGSVED
.  . ..| |.||.|.|..         .||.|.     .  ...     ..|. |   | .. |.|     ....|  .... . ..| | . .||  .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLYGCRRHAGGA-------GGLDWPARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDA------GFRPRVTDFGLARALAGQEETHVSTIVAGTL
 |.| | .  .|       .  |    .. |   |||. .||    .|||||| | .|||.|.      .   ...|||..| .   .... |.  |||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSN--AGTY

GYVPPEY-----CQTWRATVKGDVYSYGVVLLELLSGRRP
 .  ||      |...   .  ||.|.|||| |.|... |
AWMAPEVIQQFRCEKYSEKC--DVWSWGVVLWEMLTREVP
Kinase LRR10a_b-1.AA TKL-Unique 793-996 28 1.5e-27 94.31 In-house 1-233 (290) Show / Hide 
Range on Protein: 793-996
Range on HMM: 1-233/290
Sequence Identity: 28% (69 aa)

DSNIVGCGGFGVVYKAQLSDGSTVAIKKLI-REGPAGE--REFQAEMHTLGHIV-HENLVPLMGYSS----YGAQMLLVYELMVNGSVEDWLYG------
..| .| ||.|.|||.    |. ||||..   |..  |  .||  |  ..  .  |.|.| .|||.     | ..| .| | .  ||  | |        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--CRRHAGGAGGLDWPARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAG-----FRPRVTDFGLARALAGQEETHVSTI-------VAGTLGYV
   . .      |..  |.. ||  |.|. .|||.  | |||||.| ||.|.| .     .. .. ||||.. ..   .. ....       . |.. ..
NNNNNCK-----LNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWM

PPEYCQT--WRATVKGDVYSYGVVLLELLSGRR------P
.||         . | ||||.|.|| |.... .      |
APEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR10a_b-1.AA S_TKc 791-1063 24 1.8e-26 95.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 791-1063
Range on HMM: 1-231/231
Sequence Identity: 24% (68 aa)

FHDSNIVGCGGFGVVYKAQLSD-GSTVAIKKLIREGPAGEREFQAEMHTLGHIVHENLVPLMGYSSYGAQMLLVYELMVN--GSVEDWLYGCRRHAGGAG
..  ...| |.||.|||..  . |  ||||..        . .. |.  | .  |.|.| | ..      . .| |.. .  |.. | .  ..|| ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR-F

GLDWPARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPRVTDFGLARALAGQEETHVSTIVAGTLGYVPPEYCQTWRATV-KGDVYSYGVV
...      ..  ....|...|      ||||| | .|||||   .  ..|||||| |         | . ||. |..|| .     .  | |..| |..
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LLELLSGRRPMLDAGNYIMAGEDSGRDLHHNVEEFEDQCYSNLVEWAFLRLALDCTQDVPVRRPCMRDVCQ-----RLEDIK
| |.|.|. |     .. |  .  |                   . |   .   | |  | .||   .. |     ..    
LYEMLCGYPPFP---QMQMMFKKIG------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR10a_b-1.AA Pkinase_Tyr 791-996 26 7e-26 88.28 Pfam 1-214 (270) Show / Hide 
Range on Protein: 791-996
Range on HMM: 1-214/270
Sequence Identity: 26% (59 aa)

FHDSNIVGCGGFGVVYKAQLS-----DGSTVAIKKLIREGPAGE----REFQAEMHTLGHI-VHENLVPLMGYSS-YGAQ--MLLVYELMVNGSVEDWLY
 .     | | ||.|||. .      .. .||.|.| .||   |    ..| .|. .. ..  |.|.| |.|  .  | .  ...| |.| .|.  | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

GCRRHAGGAGGLDWPARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPRVTDFGLARALAGQEET-HVSTIVAGTLGYVPPEYCQTWRATV
  |    . . |. .  |. ..  |.|. .|.      .||||  | |.|.. ..  ...||||||..   ..  ....         .||  .. . |.
KHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTT

KGDVYSYGVVLLELLS-GRRP
| ||.|.||.. |... |. |
KSDVWSFGVLMWEIFTYGEQP
Kinase LRR10a_b-1.AA RIPK 901-1005 34 4.9e-22 71.86 In-house 116-236 (290) Show / Hide 
Range on Protein: 901-1005
Range on HMM: 116-236/290
Sequence Identity: 34% (42 aa)

TARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPRVTDFGLARALAGQEETH-----------VSTIVAGTLGYVPPEYCQ--TWRA----TVKGDVYSY
...|  .| ||  ||||||| | .|||.|. |   . |||||  . . . .             |    ||| | |||        .    | | ||||.
ISCGMCYL-HSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSF

GVVLLELLSGRRPMLDAGNYIM
..|. |.|... | .|.... |
AIVMWEVLTQKHPYEDRKCMMM
Kinase LRR10a_b-1.AA Dicty4 791-991 32 1.3e-21 69.05 In-house 1-211 (277) Show / Hide 
Range on Protein: 791-991
Range on HMM: 1-211/277
Sequence Identity: 32% (71 aa)

FHDSNIVGCGGFGVVYKAQLSDGSTVAIKKL--IREG--PAGEREFQAEMHTLGHIVHENLVPLMGYSS----YGAQMLLVYELMVNGSVEDWLYGCRRH
    .. | |.|| |||.    |. ||.|||    ..   .   || .| | .. | | |.. .||..         |. | |.|  |...  |     |
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLL-----H

A-----GGAGGLDWPARLD---VAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPRVTDFGLARALAGQEETHV-STIVAGTLGYVPPEYCQTWR
.          |||| ..     |. .|||.  | |.| | ||||| |..|.| |. .|  |.||||..     |.     . ..|| ... ||  .  .
DKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWL-HCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP

ATVKGDVYSYGVVLLELL
 . | ||||.| || |.|
YNEKADVYSFGIVLWEIL
Kinase LRR10a_b-1.AA Dicty4-Unclassified 895-999 35 1.8e-21 70.27 In-house 112-210 (263) Show / Hide 
Range on Protein: 895-999
Range on HMM: 112-210/263
Sequence Identity: 35% (37 aa)

LDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPRVTDFGLARALAGQEETHVSTIVAGTLGYVPPEYCQTWRATVKGDVYSYGVVLLELLSGR
. .|.  |.|. .||   .  .||||.|.||||.|  |  .. |||..|     . .   | .|||     ||       . | |||||...| ||. | 
IKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGD

RPMLD
 | ..
EPYQE
Kinase LRR10a_b-1.AA DRK 889-991 35 3.3e-20 65.18 In-house 95-196 (258) Show / Hide 
Range on Protein: 889-991
Range on HMM: 95-196/258
Sequence Identity: 35% (37 aa)

LDWPARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPRVTDFGLARALAGQEETHVSTIVAGTLGYVPPEYCQTWRATVKGDVYSYGVVLL
.||| ..  ..  |.|. .| |.| | ||||| |  | | |  ..  | ||||.      ..        || . . ||     | | | ||||...|| 
MDWPLMKQMMFDCAKGMIYL-HCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLW

ELL
|..
ECV
Kinase LRR10a_b-1.AA TyrKc 791-1059 20 5.2e-20 73.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 791-1059
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FHDSNIVGCGGFGVVYKAQLSDGSTVAIKKLIREGPAGEREFQAEMHTLGHI--VHENLVPLMGYSSYG-------AQMLLVYELMVNGSVEDWLYGCRR
 .   . |.| ||.|||....   .||.|.|  .    ...|  |.  . ..   |.|.| | |. . .        ....| |.| .|.  | |  .|.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

HAGGAGGLDWPARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPRVTDFGLARALAGQ-------EETHVST--IVA--GTLGYVPPEYCQ
.      | ..  |. ..  |.|  .||.    ..||||  | |.|...... ...||||.|..          .  ....         .   .||  .
K------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

TWRATVKGDVYSYGVVLLELLSGRRPMLDAGNYIMAGEDSGRDLHHNVEEF-EDQCYSNL-------VEWAFLRLALDCTQDVPVRRPCMRDVCQRL
. . | | ||.|.||.. |...  . .    . |     | ......|..     .  |           .  .. ..| .  |  ||.........
YGKFTTKSDVWSFGVCMWEIFT--YGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRR10a_b-1.AA LRRK 889-997 33 2e-16 54.58 In-house 161-283 (351) Show / Hide 
Range on Protein: 889-997
Range on HMM: 161-283/351
Sequence Identity: 33% (42 aa)

LDWPARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILL---D---------AGFRPRVTDFGLARALAGQEETH-VSTIVAGTLGYVPPEYCQ---TW
..|  .| .|.  |.|...| ||..||||||| |  ||||   .         |     . |||. | .  |  .. |   . |. |.. ||  .   . 
ISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEE

RATVKGDVYSYGVVLLELLSGR-RPM
  | | |.||.|..| |||... .|.
EYTEKVDCYSFGMILWELLTRQHHPF
Kinase LRR10a_b-1.AA LRRK 791-854 19 2.8e-10 32.55 In-house 1-126 (351) Show / Hide 
Range on Protein: 791-854
Range on HMM: 1-126/351
Sequence Identity: 19% (24 aa)

FHDSNIVGCGGFG-VVYKAQLSD---------------------------GSTVAIKKLIREG----------------------------------PAG
.   . .| |||| .||.| . .                           ...|||||..|..                                  .  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EREFQAEMHTLGHIVHENLVPLMGYS
 |||. |.. . |  | |.|.|.|..
FREFRHEVWIMSHLNHPNIVSLKGFC
Kinase LRR10a_b-1.AA Dicty4-Unclassified 813-870 34 0.000223 10.86 In-house 22-87 (263) Show / Hide 
Range on Protein: 813-870
Range on HMM: 22-87/263
Sequence Identity: 34% (23 aa)

GSTVAIKKLIREGPAGER-----EFQAEMHTLGHIVHENLVPLMGYSSYG----AQMLLVYELMVNG
|  ||.||.  |.    |     .| .|   || | | ||| . ||.       . |  | |.|  |
GKDVAVKKF-NENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKG
Kinase LRR10a_b-1.AA RIPK 797-809 69 0.002207 7.35 In-house 1-13 (290) Show / Hide 
Range on Protein: 797-809
Range on HMM: 1-13/290
Sequence Identity: 69% (9 aa)

VGCGGFGVVYKAQ
|| |||| |.||.
VGGGGFGEVFKAR
Kinase LRR10a_b-1.AA DRK 1034-1061 35 0.007979 5.44 In-house 231-258 (258) Show / Hide 
Range on Protein: 1034-1061
Range on HMM: 231-258/258
Sequence Identity: 35% (10 aa)

FLRLALDCTQDVPVRRPCMRDVCQRLED
. .|  ||    |  || | .. .||| 
YIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase LRR10a_b-1.AA LRRK 1040-1061 31 0.013999 4.93 In-house 330-351 (351) Show / Hide 
Range on Protein: 1040-1061
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

DCTQDVPVRRPCMRDVCQRLED
.| |  | .|| . .. .||..
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR10a_b-1.AA Dicty4-Unclassified 1036-1059 33 0.016242 4.39 In-house 240-263 (263) Show / Hide 
Range on Protein: 1036-1059
Range on HMM: 240-263/263
Sequence Identity: 33% (8 aa)

RLALDCTQDVPVRRPCMRDVCQRL
.|  .|  . | .|| | .. |.|
KLIKWCWHNDPNKRPTMNQIIQYL
Kinase LRR10a_b-1.AA Dicty4 1046-1061 38 0.310275 0.07 In-house 260-277 (277) Show / Hide 
Range on Protein: 1046-1061
Range on HMM: 260-277/277
Sequence Identity: 38% (7 aa)

PVRRPCMRDVCQR--LED
| .|| .  . ||  || 
PQHRPSFEEIIQRRILEH