LRR10a_b-2

Species: S.moellendorffii
Alias: LRR10a_b-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR10a

Sequence

Name Sequence Type Origin Length Description Download
LRR10a_b-2.AA Protein None 1067 None Fasta, JSON
LRR10a_b-2.NA RNA None 3204 None Fasta, JSON
LRR10a_b-2.kin_dom Protein Kinase Domain None 206 None Fasta, JSON

Protein domain

Protein domains of LRR10a_b-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR10a_b-2.AA LRRNT_2 6-40 38 8.9e-10 34.66 Pfam 8-46 (46) Show / Hide
Range on Protein: 6-40
Range on HMM: 8-46/46
Sequence Identity: 38% (15 aa)

LLRFKRSLL--LANPSALQSWKPDD--RSPCEWQGVSCV
||.|| ||     ....|.||.|..   ..| | ||.| 
LLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD

LRR_1 LRR10a_b-2.AA LRR_1 43-65 33 0.092008 10.42 Pfam 1-26 (26) Show / Hide
Range on Protein: 43-65
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

HVISIDLSN-Q--RLTGPIPDA-IGLL
.  ..|||.    .||| ||.  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 138-160 40 2.5e-05 23.05 Pfam 1-26 (26) Show / Hide
Range on Protein: 138-160
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ALERLDLSG-N--QFHGSIPSS-LGGC
 |..||||| |  .. |.||.| . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 113-136 44 0.00052 18.39 Pfam 1-26 (26) Show / Hide
Range on Protein: 113-136
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

GIQFLNISS-N--NLTGAIPPELFSQC
 .| |..|. |  |||| |||. | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 91-112 25 0.016676 13.05 Pfam 1-26 (26) Show / Hide
Range on Protein: 91-112
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

GLRTLNISN-N--SLSGSLPR--ILSP
 |..|..|. |  .|.|..|   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 67-89 37 0.037067 11.82 Pfam 1-26 (26) Show / Hide
Range on Protein: 67-89
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

DLESLILAA-N--SLNGSIPDA-IGNL
 |..| |   |  .| |.||.  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP LRR10a_b-2.AA LRR_TYP 89-112 37 0.058753 9.94 SMART 1-24 (24) Show / Hide
Range on Protein: 89-112
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

LGGLRTLNISNNSLSGSLPRILSP
|. ||.|. ||| |.   |.....
LPNLRELDLSNNQLTHLPPGAFQG

LRR_TYP LRR10a_b-2.AA LRR_TYP 136-160 32 0.33643 3.73 SMART 1-24 (24) Show / Hide
Range on Protein: 136-160
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

CQALERLDLSGNQFHGSIPSSLGGC
  .|..||||.||.  ..|. . ..
LPNLRELDLSNNQL-THLPPGAFQG

LRR_1 LRR10a_b-2.AA LRR_1 162-184 33 0.095664 10.36 Pfam 1-26 (26) Show / Hide
Range on Protein: 162-184
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ALEVLSLEN-T--NLVGEIPPE-LASG
 |..|.| . .  ||.|.|||. . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP LRR10a_b-2.AA LRR_TYP 256-279 37 0.000231 21.74 SMART 1-24 (24) Show / Hide
Range on Protein: 256-279
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

LRSLRFLVLGRNNITELPASIANC
|..|| | |..|..|.||. . ..
LPNLRELDLSNNQLTHLPPGAFQG

LRR_1 LRR10a_b-2.AA LRR_1 258-279 33 0.001218 17.08 Pfam 1-26 (26) Show / Hide
Range on Protein: 258-279
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLRFLVLGR-N--NIT-ELPAS-IANC
.|. | |.. |  |.| ..| | . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 211-234 44 0.00147 16.79 Pfam 1-26 (26) Show / Hide
Range on Protein: 211-234
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

SLRNIDLSL-N--NLTGEIPREIFRSA
.|. .|||  |  ||||.|| ..| . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP LRR10a_b-2.AA LRR_TYP 186-210 40 0.015035 14.79 SMART 1-24 (24) Show / Hide
Range on Protein: 186-210
Range on HMM: 1-24/24
Sequence Identity: 40% (10 aa)

LASLTDLNLANNHLVGSIPGGLFVP
| .|. |.| ||.|  ..| |.| .
LPNLRELDLSNNQL-THLPPGAFQG

LRR_1 LRR10a_b-2.AA LRR_1 188-207 34 0.042208 11.62 Pfam 1-26 (26) Show / Hide
Range on Protein: 188-207
Range on HMM: 1-26/26
Sequence Identity: 34% (9 aa)

SLTDLNLAN-N--HLVGSIPG---GL
.|. |.| . |  .|.|.||    .|
NLQHLDLSGCNCCNLTGHIPPSCFNL

LRR_1 LRR10a_b-2.AA LRR_1 235-256 37 0.054021 11.24 Pfam 1-26 (26) Show / Hide
Range on Protein: 235-256
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

DLENLFLSQ-N--HFT-RIPPE-IGLL
 |. | ||  |  ..|  |||. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP LRR10a_b-2.AA LRR_TYP 234-255 34 0.700408 1.12 SMART 2-24 (24) Show / Hide
Range on Protein: 234-255
Range on HMM: 2-24/24
Sequence Identity: 34% (8 aa)

ADLENLFLSQNHFTRIPPEI-GL
  |. | || |..|..||.. . 
PNLRELDLSNNQLTHLPPGAFQG

LRR_1 LRR10a_b-2.AA LRR_1 281-303 33 0.501079 7.81 Pfam 1-26 (26) Show / Hide
Range on Protein: 281-303
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ELRVLILNE-N--LLAGEIPAV-IAKL
 |..| |.  |   | |.||   . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 305-327 33 2.892906 5.11 Pfam 1-26 (26) Show / Hide
Range on Protein: 305-327
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

KLQFLVLHT-N--GFTGGIPEW-IATS
.|| | |   |   .|| ||.. .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 330-352 44 0.000644 18.06 Pfam 1-26 (26) Show / Hide
Range on Protein: 330-352
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

QLLHLDLSD-N--RITGVIPSG-FNAT
.| |||||. |  ..|| ||.. | . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP LRR10a_b-2.AA LRR_TYP 329-351 39 0.343112 3.66 SMART 2-24 (24) Show / Hide
Range on Protein: 329-351
Range on HMM: 2-24/24
Sequence Identity: 39% (9 aa)

RQLLHLDLSDNRITGVIPSGFNA
..| .||||.|..| . |  |. 
PNLRELDLSNNQLTHLPPGAFQG

LRR_1 LRR10a_b-2.AA LRR_1 356-378 48 0.00121 17.09 Pfam 1-26 (26) Show / Hide
Range on Protein: 356-378
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

KLQFLLLAG-N--RLTGSIPPS-LGEI
.|| | | | |  .|||.|||| .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP LRR10a_b-2.AA LRR_TYP 354-378 36 0.142787 6.78 SMART 1-24 (24) Show / Hide
Range on Protein: 354-378
Range on HMM: 1-24/24
Sequence Identity: 36% (9 aa)

LAKLQFLLLAGNRLTGSIPPSLGEI
| .|. | | .|.|| ..|| . . 
LPNLRELDLSNNQLT-HLPPGAFQG

LRR_1 LRR10a_b-2.AA LRR_1 380-402 59 9.5e-07 28.1 Pfam 1-26 (26) Show / Hide
Range on Protein: 380-402
Range on HMM: 1-26/26
Sequence Identity: 59% (16 aa)

QLQFLDLSG-N--RLTGSIPPS-LGKL
.|| ||||| |  .|||.|||| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 404-426 33 0.025934 12.37 Pfam 1-26 (26) Show / Hide
Range on Protein: 404-426
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RLLWLMLAN-N--MLSGTIPRE-LGNC
.|  | | . |   |.|.|| . . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP LRR10a_b-2.AA LRR_TYP 402-426 32 0.088059 8.5 SMART 1-24 (24) Show / Hide
Range on Protein: 402-426
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

LGRLLWLMLANNMLSGTIPRELGNC
|. |  | | || |  ..|... ..
LPNLRELDLSNNQL-THLPPGAFQG

LRR_1 LRR10a_b-2.AA LRR_1 428-450 22 3.047149 5.03 Pfam 1-26 (26) Show / Hide
Range on Protein: 428-450
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

SLLWLNAAK-N--SIGGELPPE-LESM
.|  |.    |  .. |..||. . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 526-548 29 7.320681 3.68 Pfam 1-26 (26) Show / Hide
Range on Protein: 526-548
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SMGYIQLSE-N--RLSGSIPAS-YGGI
.  .. ||  |  .|.|.|| |   . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 597-619 48 0.000108 20.81 Pfam 1-26 (26) Show / Hide
Range on Protein: 597-619
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

CLQSLDLSS-N--RLSGQIPYS-LTRL
 ||.||||. |  .|.|.|| | .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 573-595 40 0.001499 16.76 Pfam 1-26 (26) Show / Hide
Range on Protein: 573-595
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLTGLNLSH-N--ALEGAIPDS-FGQF
.|. |.||. |   |.| ||.| | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR10a_b-2.AA LRR_1 550-572 40 0.058021 11.13 Pfam 1-26 (26) Show / Hide
Range on Protein: 550-572
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLSLLFLYQ-N--RLSGAIPGS-LSNL
.|  | |   |  .|.| || | . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP LRR10a_b-2.AA LRR_TYP 595-619 32 0.441831 2.76 SMART 1-24 (24) Show / Hide
Range on Protein: 595-619
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

FQCLQSLDLSSNRLSGQIPYSLTRL
   |..||||.|.|  ..|  . . 
LPNLRELDLSNNQL-THLPPGAFQG

LRR_TYP LRR10a_b-2.AA LRR_TYP 569-594 38 0.774943 0.76 SMART 1-24 (24) Show / Hide
Range on Protein: 569-594
Range on HMM: 1-24/24
Sequence Identity: 38% (10 aa)

LSNLKLTGLNLSHNALEGAIPDSFGQ
|.||  . |.||.|.|.   |. |. 
LPNL--RELDLSNNQLTHLPPGAFQG

LRR_1 LRR10a_b-2.AA LRR_1 621-643 29 4.738499 4.35 Pfam 1-26 (26) Show / Hide
Range on Protein: 621-643
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLNKFNVSY-N-PGLAGPIPF--AGQL
.| . ..|. | . | | ||     .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

Kinase LRR10a_b-2.AA IRAK 790-998 38 3.7e-61 209.48 In-house 1-226 (317) Show / Hide
Range on Protein: 790-998
Range on HMM: 1-226/317
Sequence Identity: 38% (87 aa)

FHDSNIVGCGGFGVVYKARLSDGS-TVAIKKLIREGP----AGEREFQA---EMHTLGHIVHENLVPLMGYSSYGAQKLLVYELMVNGSVEDWLYGCRRH
|| .|  | ||||.||.....    ..|.|||. .        ...||.   |. ..  . |.|.||| ||.. . .  |||..| ||| || |  |.  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLW-CQDG

AGGAGGLDWLARLDVAIGTARGLKFLHHSCSP-PIIHRDMKASNILLDAGFRPCVTDFGLARAL--AGQEETHVS-----TIVAGTLGYVPPEYCQ--TW
..    | |  |.....|||.|. |||   .  ||||.| | .|||||. | |  .||||.|    |.  | ...      .| ||. | |||.    . 
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

RATVKGDVYSYGVVLLELLSGRRPMLD
. |.| |||| |.||||.|.|.|...|
QLTKKTDVYSFGIVLLEVLTGCRAVYD

Kinase LRR10a_b-2.AA TKL 796-1058 21 3.4e-52 179.74 In-house 1-364 (364) Show / Hide
Range on Protein: 796-1058
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

VGCGGFGVVYKARLSD---------GSTVAIKKLIREGPAGERE-------------------------FQAEMHTLGHIV--HENLVPLMGYSSYGAQ-
.| ||||.|||...           | .||.||. ..    . .                         |. |  .. ..   |.|.|..|||. .. . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KLLVYELMVNGSVEDWLYGCRRHAGGAGGLDWLARLDVAIGTARGLKFLHHSCS-----PPIIHRDMKASNILLDAGFR---------
              .|.|.. .|| .. |              |  |.. |...|||. .|| .       ||||||| | .|||.|  ..         
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNP

-----PCVTDFGLAR-ALAGQEETHV----------------STIVAGTLGYVPPEY----------------CQTWRATVKGDVYSYGVVLLELLSGRR
     ....||||.|     .. ..                 .  . ||... .||                 |. . .. | ||||.|.|| |.|...|
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR

PMLDAGNY------------IMAGEDSGRDL-------HHNVEEFEDQCYSNLVEWA-FLRLALDCTQDVPVRRPCMRDVCQRL
|  | ...            .|..... | .       ||     . . . .   .  . .|. || .  |  || . .. .||
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-----K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LRR10a_b-2.AA Pkinase 790-993 25 1.9e-36 129.97 Pfam 1-209 (293) Show / Hide
Range on Protein: 790-993
Range on HMM: 1-209/293
Sequence Identity: 25% (56 aa)

FHDSNIVGCGGFGVVYKARLSDGST-VAIKKLIREGPAGEREFQA-----EMHTLGHIVHENLVPLMGYSSYGAQKLLVYELMVNG----SVEDWLYGCR
.|   ..| |.||.|||..  . .  ||.|.. ..  . . . |.     | . . .. |.| | | ..  ..    .| |.. .|    .  |.. .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

RHAGGAGGL--DWLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRP----CVTDFGLARALAGQEETHVSTIVAGTLGYVPPEYCQ-TWR
      |..  ..    ...  ..|||...|      |||||.| .|||.|    .    ...|||||. .      .  | ..||..|..|| ..    
---WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQY

ATVKGDVYSYGVVLLELLSGR
 . | |..|.|..| |.|.||
YGPKVDMWSCGCILYEMLCGR

Kinase LRR10a_b-2.AA TK 790-1058 14 2.3e-31 101.78 In-house 1-486 (486) Show / Hide
Range on Protein: 790-1058
Range on HMM: 1-486/486
Sequence Identity: 14% (69 aa)

FHDSNIVGCGGFG---VVYKARLSDGS--------------------------TVAIKKLIREGPAGEREFQA--------------EMHTLGHIV----
 .  .  | | ||   .|||... ...                          .||.| |  . .. ..||..              |.. .        
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENLVPLMGYSSYGAQK------------LLVYELMVNGS----VEDWLYGCRRHAGG-----------------------------------------
 |.|.| | |... |. |            ..| |.| .|.      |.|  ||...                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------AGGLDWLARLDVAIGTARGLKFLHHS----CSPPIIHRDMKASNILLDAGFR-----------PCVTDFG--
                             . |.   .|  .   |.|. .||        . ..|||  | |.|.. . .             ..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LARALAGQEETHVSTIVAGTLG------------------------YVPPEYCQ---------TWRATVKGDVYSYGVVLLELLS-G-RRPMLD
      |||..   .. ....   ....                        . .||  .         . . | | ||.|.||.. |... |   .  .
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

AGN----------YIMAGEDSGRDL---------HHNVEEFEDQCYS---------NLVEWAFLRLALDCTQDVPVRRPCMRDVCQRL
  |           .|    .|. |         . .  .  ..| .         .  . .. .| ..| .  | .|| .... ..|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase LRR10a_b-2.AA MLK 790-995 26 1.1e-25 86.21 In-house 1-235 (291) Show / Hide
Range on Protein: 790-995
Range on HMM: 1-235/291
Sequence Identity: 26% (63 aa)

FHDSNIVGCGGFGVVYKARLSDGS----TVAIKKLI--REGPAGE-----REFQAEMHTLGHIVHEN----LVPLMGY-SSYGAQKLLVYELMVNGSVED
.  . ..| |.||.|.|.|         .||.|.     .  ...     ..|. |   | .. |.|     ....|  .... . ..| | . .||  .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLYGCRRHAGGA-------GGLDWLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDA------GFRPCVTDFGLARALAGQEETHVSTIVAGTL
 |.| | .  .|       .  |    .. |   |||. .||    .|||||| | .|||.|.      .    ..|||..| .   .... |.  |||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSN--AGTY

GYVPPEY-----CQTWRATVKGDVYSYGVVLLELLSGRRP
 .  ||      |...   .  ||.|.|||| |.|... |
AWMAPEVIQQFRCEKYSEKC--DVWSWGVVLWEMLTREVP

Kinase LRR10a_b-2.AA S_TKc 790-1062 25 1.2e-25 92.4 SMART 1-231 (231) Show / Hide
Range on Protein: 790-1062
Range on HMM: 1-231/231
Sequence Identity: 25% (71 aa)

FHDSNIVGCGGFGVVYKARLSD-GSTVAIKKLIREGPAGEREFQAEMHTLGHIVHENLVPLMGYSSYGAQKLLVYELMVN--GSVEDWLYGCRRHAGGAG
..  ...| |.||.|||.|  . |  ||||..        . .. |.  | .  |.|.| | ..        .| |.. .  |.. | .  ..|| .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

GLDWLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPCVTDFGLARALAGQEETHVSTIVAGTLGYVPPEYCQTWRATV-KGDVYSYGVV
     ||  ..  ....|...|      ||||| | .|||||   .  ..|||||| |         | . ||. |..|| .     .  | |..| |..
FPE-HARF-YMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LLELLSGRRPMLDAGNYIMAGEDSGRDLHHNVEEFEDQCYSNLVEWAFLRLALDCTQDVPVRRPCMRDVCQ-----RLEDIK
| |.|.|. |     .. |  .  |                   . |   .   | |  | .||   .. |     ..    
LYEMLCGYPPFP---QMQMMFKKIG------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LRR10a_b-2.AA TKL-Unique 792-995 28 2.7e-25 86.23 In-house 1-233 (290) Show / Hide
Range on Protein: 792-995
Range on HMM: 1-233/290
Sequence Identity: 28% (68 aa)

DSNIVGCGGFGVVYKARLSDGSTVAIKKLI-REGPAGE--REFQAEMHTLGHIV-HENLVPLMGYSS----YGAQKLLVYELMVNGSVEDWLYG------
..| .| ||.|.|||.    |. ||||..   |..  |  .||  |  ..  .  |.|.| .|||.     | ..  .| | .  ||  | |        
FWNKIGEGGYGQVYKG-KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--CRRHAGGAGGLDWLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAG-----FRPCVTDFGLARALAGQEETHVSTI-------VAGTLGYV
   . .      |... |.. ||  |.|. .|||.  | |||||.| ||.|.| .     ..  . ||||.. ..   .. ....       . |.. ..
NNNNNCK-----LNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWM

PPEYCQT--WRATVKGDVYSYGVVLLELLSGRR------P
.||         . | ||||.|.|| |.... .      |
APEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP

Kinase LRR10a_b-2.AA Pkinase_Tyr 790-995 26 7.5e-24 81.41 Pfam 1-214 (270) Show / Hide
Range on Protein: 790-995
Range on HMM: 1-214/270
Sequence Identity: 26% (59 aa)

FHDSNIVGCGGFGVVYKARLS-----DGSTVAIKKLIREGPAGE----REFQAEMHTLGHI-VHENLVPLMGYSS-YGAQ--KLLVYELMVNGSVEDWLY
 .     | | ||.|||...      .. .||.|.| .||   |    ..| .|. .. ..  |.|.| |.|  .  | .   ..| |.| .|.  | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

GCRRHAGGAGGLDWLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPCVTDFGLARALAGQEET-HVSTIVAGTLGYVPPEYCQTWRATV
  |    . . |.    |. ..  |.|. .|.      .||||  | |.|.. ..   ..||||||..   ..  ....         .||  .. . |.
KHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTT

KGDVYSYGVVLLELLS-GRRP
| ||.|.||.. |... |. |
KSDVWSFGVLMWEIFTYGEQP

Kinase LRR10a_b-2.AA RIPK 900-1004 34 2.2e-21 69.58 In-house 116-236 (290) Show / Hide
Range on Protein: 900-1004
Range on HMM: 116-236/290
Sequence Identity: 34% (42 aa)

TARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPCVTDFGLARALAGQEETH-----------VSTIVAGTLGYVPPEYCQ--TWRA----TVKGDVYSY
...|  .| ||  ||||||| | .|||.|. |   . |||||  . . . .             |    ||| | |||        .    | | ||||.
ISCGMCYL-HSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSF

GVVLLELLSGRRPMLDAGNYIM
..|. |.|... | .|.... |
AIVMWEVLTQKHPYEDRKCMMM

Kinase LRR10a_b-2.AA Dicty4-Unclassified 894-998 35 9.3e-21 67.79 In-house 112-210 (263) Show / Hide
Range on Protein: 894-998
Range on HMM: 112-210/263
Sequence Identity: 35% (37 aa)

LDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPCVTDFGLARALAGQEETHVSTIVAGTLGYVPPEYCQTWRATVKGDVYSYGVVLLELLSGR
. .|.  |.|. .||   .  .||||.|.||||.|  |   . |||..|     . .   | .|||     ||       . | |||||...| ||. | 
IKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGD

RPMLD
 | ..
EPYQE

Kinase LRR10a_b-2.AA TyrKc 790-1058 20 2.4e-18 68.2 SMART 1-280 (280) Show / Hide
Range on Protein: 790-1058
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FHDSNIVGCGGFGVVYKARLSDGSTVAIKKLIREGPAGEREFQAEMHTLGHI--VHENLVPLMGYSSYG-------AQKLLVYELMVNGSVEDWLYGCRR
 .   . |.| ||.|||....   .||.|.|  .    ...|  |.  . ..   |.|.| | |. . .        . ..| |.| .|.  | |  .|.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

HAGGAGGLDWLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPCVTDFGLARALAGQ-------EETHVST--IVA--GTLGYVPPEYCQ
.      | .   |. ..  |.|  .||.    ..||||  | |.|......  ..||||.|..          .  ....         .   .||  .
K------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

TWRATVKGDVYSYGVVLLELLSGRRPMLDAGNYIMAGEDSGRDLHHNVEEF-EDQCYSNL-------VEWAFLRLALDCTQDVPVRRPCMRDVCQRL
. . | | ||.|.||.. |...  . .    . |     | ......|..     .  |           .  .. ..| .  |  ||.........
YGKFTTKSDVWSFGVCMWEIFT--YGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase LRR10a_b-2.AA DRK 888-990 34 5.5e-18 57.54 In-house 95-196 (258) Show / Hide
Range on Protein: 888-990
Range on HMM: 95-196/258
Sequence Identity: 34% (36 aa)

LDWLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLDAGFRPCVTDFGLARALAGQEETHVSTIVAGTLGYVPPEYCQTWRATVKGDVYSYGVVLL
.||  ..  ..  |.|. .| |.| | ||||| |  | | |  ..  | ||||.      ..        || . . ||     | | | ||||...|| 
MDWPLMKQMMFDCAKGMIYL-HCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLW

ELL
|..
ECV

Kinase LRR10a_b-2.AA LRRK 888-996 32 3.6e-16 53.67 In-house 161-283 (351) Show / Hide
Range on Protein: 888-996
Range on HMM: 161-283/351
Sequence Identity: 32% (41 aa)

LDWLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILL---DAGF------RPC---VTDFGLARALAGQEETH-VSTIVAGTLGYVPPEYCQ---TW
..|  .| .|.  |.|...| ||..||||||| |  ||||   ....       .    . |||. | .  |  .. |   . |. |.. ||  .   . 
ISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEE

RATVKGDVYSYGVVLLELLSGR-RPM
  | | |.||.|..| |||... .|.
EYTEKVDCYSFGMILWELLTRQHHPF

Kinase LRR10a_b-2.AA LRRK 790-853 19 7.3e-11 34.65 In-house 1-126 (351) Show / Hide
Range on Protein: 790-853
Range on HMM: 1-126/351
Sequence Identity: 19% (24 aa)

FHDSNIVGCGGFG-VVYKARLSD---------------------------GSTVAIKKLIREG----------------------------------PAG
.   . .| |||| .||.|.. .                           ...|||||..|..                                  .  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EREFQAEMHTLGHIVHENLVPLMGYS
 |||. |.. . |  | |.|.|.|..
FREFRHEVWIMSHLNHPNIVSLKGFC

Kinase LRR10a_b-2.AA LISK 890-942 38 1.4e-10 30.39 In-house 100-153 (296) Show / Hide
Range on Protein: 890-942
Range on HMM: 100-153/296
Sequence Identity: 38% (22 aa)

WLARLDVAIGTARGLKFLHHSCSPPIIHRDMKASNILLD----AGFRPCVTDFGLAR
|  |.. | . |.|. .||  .   ||||| |. |.|..     ..|  |.|||.||
WPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFAR

Kinase LRR10a_b-2.AA LISK 795-847 28 4.4e-07 18.85 In-house 1-59 (296) Show / Hide
Range on Protein: 795-847
Range on HMM: 1-59/296
Sequence Identity: 28% (17 aa)

IVGCGGFGVVYKARLS-DGSTVAIKKLIR-----EGPAGEREFQAEMHTLGHIVHENLV
. | |.|| ||| ..  .|. .|||...|     . |. .. .. |. ..  . | | |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIV

Kinase LRR10a_b-2.AA LISK 978-995 38 0.000178 10.23 In-house 221-238 (296) Show / Hide
Range on Protein: 978-995
Range on HMM: 221-238/296
Sequence Identity: 38% (7 aa)

DVYSYGVVLLELLSGRRP
||.|.|.||.|.  ....
DVFSFGIVLCEIITRVKA

Kinase LRR10a_b-2.AA RIPK 796-808 76 0.001111 8.38 In-house 1-13 (290) Show / Hide
Range on Protein: 796-808
Range on HMM: 1-13/290
Sequence Identity: 76% (10 aa)

VGCGGFGVVYKAR
|| |||| |.|||
VGGGGFGEVFKAR

Kinase LRR10a_b-2.AA Dicty4-Unclassified 812-853 38 0.00173 7.77 In-house 22-67 (263) Show / Hide
Range on Protein: 812-853
Range on HMM: 22-67/263
Sequence Identity: 38% (18 aa)

GSTVAIKKLIREGPAGER-----EFQAEMHTLGHIVHENLVPLMGYS
|  ||.||.  |.    |     .| .|   || | | ||| . ||.
GKDVAVKKF-NENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC

Kinase LRR10a_b-2.AA DRK 1033-1060 35 0.007979 5.44 In-house 231-258 (258) Show / Hide
Range on Protein: 1033-1060
Range on HMM: 231-258/258
Sequence Identity: 35% (10 aa)

FLRLALDCTQDVPVRRPCMRDVCQRLED
. .|  ||    |  || | .. .||| 
YIQLMNDCWNEDPQHRPSMQECLERLEA

Kinase LRR10a_b-2.AA LRRK 1039-1060 31 0.013999 4.93 In-house 330-351 (351) Show / Hide
Range on Protein: 1039-1060
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

DCTQDVPVRRPCMRDVCQRLED
.| |  | .|| . .. .||..
HCWQHDPKKRPHFSQIVKRLSQ

Kinase LRR10a_b-2.AA Dicty4-Unclassified 1035-1058 33 0.016242 4.39 In-house 240-263 (263) Show / Hide
Range on Protein: 1035-1058
Range on HMM: 240-263/263
Sequence Identity: 33% (8 aa)

RLALDCTQDVPVRRPCMRDVCQRL
.|  .|  . | .|| | .. |.|
KLIKWCWHNDPNKRPTMNQIIQYL

Kinase LRR10a_b-2.AA LISK 1032-1058 37 0.028989 2.93 In-house 270-296 (296) Show / Hide
Range on Protein: 1032-1058
Range on HMM: 270-296/296
Sequence Identity: 37% (10 aa)

AFLRLALDCTQDVPVRRPCMRDVCQRL
.||.|..||.   |  ||.  .. |.|
PFLDLCFDCCKYDPKNRPSFKEIVQWL