Gene LRR2_d (S.moellendorffii)

LRR2_d

Species: S.moellendorffii
Alias: LRR2_d
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR2

Sequence

Name Sequence Type Origin Length Description Download
LRR2_d.AA Protein None 616 None Fasta, JSON
LRR2_d.NA RNA None 1851 None Fasta, JSON
LRR2_d.kin_dom Protein Kinase Domain None 204 None Fasta, JSON

Protein domain

Protein domains of LRR2_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR2_d.AA LRRNT_2 25-61 40 2.5e-07 26.68 Pfam 5-46 (46) Show / Hide 
Range on Protein: 25-61
Range on HMM: 5-46/46
Sequence Identity: 40% (17 aa)

GNALAELKSKLW--DP-KNALRSWDANL--VNPCSWLYVDCD
| || ..|| |   ||  ..|.||...   ...|||  | ||
GQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR2_d.AA LRR_1 89-111 37 0.010049 13.83 Pfam 1-26 (26) Show / Hide 
Range on Protein: 89-111
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLQNLRMKG-N--LISGSLPPQ-LGTL
||| | . | |   ..|..||  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_d.AA LRR_1 113-135 48 0.003289 15.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 113-135
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

GLLNLDLSA-N--NFTGSIPST-LTNL
 |  ||||  |  |.||.||.  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_d.AA LRR_1 137-158 37 0.028036 12.25 Pfam 1-26 (26) Show / Hide 
Range on Protein: 137-158
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLRTLLLNN-N--SLTGSIPS--TLTL
.|..| |.. |  .|||.||.     |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_d.AA LRR_1 161-185 39 0.00827 14.13 Pfam 1-26 (26) Show / Hide 
Range on Protein: 161-185
Range on HMM: 1-26/26
Sequence Identity: 39% (11 aa)

SLQFLDVSY-N--NLSGPLPPKGTISEF
.|| ||.|. |  ||.| .||  ..  .
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
Kinase LRR2_d.AA TKL 293-564 20 1.2e-59 204.53 In-house 1-364 (364) Show / Hide 
Range on Protein: 293-564
Range on HMM: 1-364/364
Sequence Identity: 20% (79 aa)

LGQGGFGKVYKGSLEN---------GKLVAVKRLRTDQNISAGG----------------------EQAFQTEVEIIGLAV--HRNLLRLDGFCITPSE-
.|.||||.|||| . .         || ||||....... .                            |. |.||  .    | |.... |.|. |.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RILVYPFMPNGSVASRLRKLKINHLKTLDWETRKQIALGAAHGLRYLHVHCS-----PRIIHRDVKAANVLLDKDFQ-----------
              .|. ..|.||  ..|            |. | ..||..| |. ||| .       | ||||| | .|.|.|....           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AVVGDFGLAKLIDT------------------KNTHITTNVRGTPGHIAPEYLS----------------TGKSSEKTDVFGYGVLMLELITGKRAF
   . ..||||.. ...                  .|   | ...|||.. ||| |                  .. |||.||. .|... |..|..|  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

DLARLFDDDDVMLLDWVKR----FQQEGRLSELVDPKLR----H----SYQPNEVEKLTQIALLCTQASPSDRPKMVEVVSML
        .| .  ... .      .... ..   | .     .    .  |.  . . ...  | .. |..|| . |... |
------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR2_d.AA IRAK 287-492 35 7.2e-58 198.56 In-house 1-223 (317) Show / Hide 
Range on Protein: 287-492
Range on HMM: 1-223/317
Sequence Identity: 35% (80 aa)

FSDKNVLGQGGFGKVYKGSLENGK-LVAVKRLRTDQNISAGG-EQAFQT---EVEIIGLAVHRNLLRLDGFCITPSERILVYPFMPNGSVASRLRKLK-I
|.  |..|.|||| ||.| . |    .|||.|.   ..| .. .| ||.   |...  .  | |.. | |.|. ...  ||||.|||||   ||. ..  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

NHLKTLDWETRKQIALGAAHGLRYLHVHCSP-RIIHRDVKAANVLLDKDFQAVVGDFGLAKLI----DTKNTHI----TTNVRGTPGHIAPEYLS--TGK
. .| | | .|. |..|.| |...||   .   |||.|.| ||.|||..|..  .||||.       . . . .    |  ||||    .||..   .|.
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

SSEKTDVFGYGVLMLELITGKRA
 . ||||.  |.  ||..|| ||
LTKKTDVYSFGIVLLEVLTGCRA
Kinase LRR2_d.AA TK 287-564 15 3.3e-41 135.37 In-house 1-486 (486) Show / Hide 
Range on Protein: 287-564
Range on HMM: 1-486/486
Sequence Identity: 15% (78 aa)

FSDKNVLGQGGFG---KVYKGSLENGK--------------------------LVAVKRLRTDQNISAGGEQA--------------FQTEVEIIG--LA
    ..||.| ||   .|||| .....                           |||| |. . . |.  ...              .  | ..    | 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

VHRNLLRLDGFCITP------------SERILVYPFMPNGS----VASRLRKLKINHLK-----------------------------------------
 | |..|| | |  .               ..|  .||.|.      . ||| . .  .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------TLDWETRKQIALGAAHGLRYLHVH----CSPRIIHRDVKAANVLLDKDFQ-----------AVVGDFG--
                              .|. ...  ... .| |..||| .      ....|||. | |.|.... .           . ..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LAKLIDTKNTHITTNVRGTP-------------------GH------IAPEYLS---------TGKSSEKTDVFGYGVLMLELIT-GKRAFDLA
      ||. |. .    ... .||.                   |        ||| |          .|| ..|.||. .|||| |. | |.  .   
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

RLF------DDDDVMLLDWVKRFQQE-----------GRLS--ELVDP----KLRHSYQPNEVEKLTQIALLCTQASPSDRPKMVEVVSML
         . |.  ... ..| ...            |.   ..  .    .  |  .. . | . .. . | .. |.||| . .....|
MSNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR2_d.AA Pkinase 287-490 25 5e-40 142.6 Pfam 1-209 (293) Show / Hide 
Range on Protein: 287-490
Range on HMM: 1-209/293
Sequence Identity: 25% (55 aa)

FSDKNVLGQGGFGKVYKGSLENG-KLVAVKRLRTDQNISAGGEQAFQ-TEVEIIGLAVHRNLLRLDGFCITPSERILVYPFMPNG----SVASRLRKLKI
.  . ..|.|.||.|||.   .  |.||||... . . |   ....  .|..|     | | .|| ... ....  .| .....|    . .....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

NHLKTL--DWETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLDKDFQA----VVGDFGLAKLIDTKNTHITTNVRGTPGHIAPEYLS-TGKSSEK
   ...  .... | ...  . || |.| .   .|||||.| .|.|.|.. .      ..||||||..|. | . .| . |||. .||| .    . . |
WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

TDVFGYGVLMLELITGK
 |....|... |...|.
VDMWSCGCILYEMLCGR
Kinase LRR2_d.AA Dicty4 282-490 33 7.9e-37 120.47 In-house 1-214 (277) Show / Hide 
Range on Protein: 282-490
Range on HMM: 1-214/277
Sequence Identity: 33% (74 aa)

IATDNFSDKNVLGQGGFGKVYKGSLENGKLVAVKRL-RTDQNISAGGEQAFQTEVEIIGLAVHRNLLRLDGFCI----TPSERILVYPFMPNGSVASRLR
|.....     .|.|.||.||||.   || |||| |  . || ..   ..|  ||.| .   | |.. . | |.    .|..   |  .|| |...| |.
INIEQR-----IGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLH

K--LKINHLKTLDWETRKQ---IALGAAHGLRYLHVHCSPRIIHRDVKAANVLLDKDFQAVVGDFGLAKLIDTKNTHIT--TNVRGTPGHIAPEYLSTGK
.        ..|||...|.   .|. || |. .||  | |.||||| |..| | ||.... |.||||.... .  .| .  . . |||.  ||| .    
DKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP

SSEKTDVFGYGVLMLELITGK
  || ||. .| .  |. |..
YNEKADVYSFGIVLWEILTRQ
Kinase LRR2_d.AA Dicty4-Unclassified 290-489 32 3.1e-36 121.56 In-house 4-204 (263) Show / Hide 
Range on Protein: 290-489
Range on HMM: 4-204/263
Sequence Identity: 32% (67 aa)

KNVLGQGGFGKVYKGSLENGKLVAVKRLRTDQNISA-GGEQAFQTEVEIIGLAVHRNLLRLDGFCITP----SERILVYPFMPNGSVASRLRKLKINHLK
   .|.| | ||.||    || |||| .   .        | |  |||| |.  | ||... | || |    |  . |  ||. |              .
DQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

TLDWET--RKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLDKDFQAVVGDFGLAKLIDTKNTHITTNVRGTPGHIAPEYLSTGKSSEKTDVFGYGVL
 .  .      .|.  | |. .||   .  .||||.|..|.|.||.| . ..|||..  ||  ..   | . |||   .|| |       | ||. |...
PIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVID--FNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

MLELITG
. ||.||
LYELATG
Kinase LRR2_d.AA MLK 287-490 26 1.4e-35 120.95 In-house 1-233 (291) Show / Hide 
Range on Protein: 287-490
Range on HMM: 1-233/291
Sequence Identity: 26% (63 aa)

FSDKNVLGQGGFGKVYKGSLENGKL-----VAVKRLRTDQNISAGGE----QAFQTEVEIIGLAVHRN----LLRLDGFCITP-SERILVYPFMPNGSVA
.  . ..| |.||||.||   | |.     ||||| |..   ... .    ..|..|...     |.|      .. | |. | ..  .|  ....|| .
IQFHEWIGSGSFGKVWKGRWRN-KDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

SRLRKLKI------NHLK---TLDWETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLD------KDFQAVVGDFGLAKLIDTKNTHITTNVRGTP
. |.  ..      .  |   . | .   ..||  |.|. ||| .  . ||||| |  |.|.|      .. .... |||... . ..     .. .||.
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTY

GHIAPEYL---STGKSSEKTDVFGYGVLMLELITGK
   ||| .     .| ||| ||. .||.. |..|..
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase LRR2_d.AA S_TKc 287-564 21 1.5e-34 122.05 SMART 1-231 (231) Show / Hide 
Range on Protein: 287-564
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

FSDKNVLGQGGFGKVYKGSLEN-GKLVAVKRLRTDQNISAGGEQAFQTEVEIIGLAVHRNLLRLDGFCITPSERILVYPFMPN--GSVASRLRKLKINHL
.   ...|.|.||||||.   . |..||.|...          . .. |..|     | |. .| ... . ..  .|  ....  |.. ....| . . |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-KTLDWETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLDKDFQAVVGDFGLAKLIDTKNTHITTNVRGTPGHIAPEYLSTGKSSEKTDVFGYGVL
 . ..  . . ..   . .| |.| |    |||||.| .|.|||.  .  ..|||||...        | . |||  .||| |  | . .| |.   |..
RFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCI

MLELITGKRAFDLARLFDDDDVMLLDWVKRFQQEGRLSELVDPKLRHSYQPNEVEKLTQIALLCTQASPSDRPKMVEVVS---------ML
. |...|.  |.       .. |... ..                         . . ..   | |  |..||   |.            .
LYEMLCGYPPFP-------QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR2_d.AA TyrKc 287-564 24 2.2e-33 118.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 287-564
Range on HMM: 1-280/280
Sequence Identity: 24% (75 aa)

FSDKNVLGQGGFGKVYKGSLENGKLVAVKRLRTDQNISAGGEQAFQTEVEIIGLA--VHRNLLRLDGFCITP-------SERILVYPFMPNGSVASRLRK
 . . .|| | ||.|||| .     |||| |. |       ...|  | .|       | |..|| | |...           .|  .||.|.  ..|||
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LKINHLKTLDWETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLDKDFQAVVGDFGLAKLIDTK----NTHITTNVRGTPGHI--------APEYL
 . .    | ...  .... .| | .||| .   ..||||  | |.|....... ..||||.. |. .      . .  .... |          ||| .
HRPK----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

STGKSSEKTDVFGYGVLMLELITGKRAFDLARLFDDDDV---MLLDWVKRFQQEGRLSELVDPKLRHSYQPNE-----VEKLTQIALLCTQASPSDRPKM
 .|| ..|.||. .||.| |. |      .      ...   |  . | .. ..|.  .  .  .     |        ... || . | .. |.||| .
NYGKFTTKSDVWSFGVCMWEIFT------YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTF

VEVVSML
 |... .
SEIHECF
Kinase LRR2_d.AA Pkinase_Tyr 287-488 29 9.3e-33 111.56 Pfam 1-209 (270) Show / Hide 
Range on Protein: 287-488
Range on HMM: 1-209/270
Sequence Identity: 29% (65 aa)

FSDKNVLGQGGFGKVYKGSLE-----NGKLVAVKRLRTDQNISAGGE---QAFQTEVEIIGLA-VHRNLLRLDGFCITPSER---ILVYPFMPNGSVASR
 .   .||.| ||.|||| .      ..  |||| |.   . .   .   ..|  |..|      | |..|| | |.  .|    ..| ..||.|.  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LRKLKINHLKTLDWETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLDKDFQAVVGDFGLAKLI-----D-TKNTHITTNVRGTPGHIAPEYLSTG
||| . .  . |. ..  |...  | |. ||. .    .||||. | |.|....... ..|||||..|       .| ..    .. .    ||| ...|
LRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYG

KSSEKTDVFGYGVLMLELIT
| ..|.||  .|||| |..|
KFTTKSDVWSFGVLMWEIFT
Kinase LRR2_d.AA TKL-Unique 289-491 29 2.9e-32 111.12 In-house 1-226 (290) Show / Hide 
Range on Protein: 289-491
Range on HMM: 1-226/290
Sequence Identity: 29% (69 aa)

DKNVLGQGGFGKVYKGSLENGKLVAVKRLRTDQNISAGGEQAFQTEVEIIGLAV-HRNLLRLDGFCI----TPSERILVYPFMPNGSVASRLRKLKI---
. |..|.||.|.||||   .|. ||.|..     .|   .| |  || ..     | |.... |.|.    .|.....|  ..| ||    |...     
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGS----LYDVLHQNN

------NHLKTLDWETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLDKD-----FQAVVGDFGLAKLIDTKNTHITTNV--------RGTPGHIA
      |  ..|... | ..|. .| |. ||| ||.| ||||| |  |.|.| .     ... . ||||.|. .. |. ....          |..  .|
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLH-HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMA

PEYLST--GKSSEKTDVFGYGVLMLELITGKR
|| |.    . ||| ||. .|. . |..|.|.
PEVLRMNFCQYSEKSDVYSFGIVLWEIATRKI
Kinase LRR2_d.AA LRRK 287-494 23 1.1e-29 102.24 In-house 1-284 (351) Show / Hide 
Range on Protein: 287-494
Range on HMM: 1-284/351
Sequence Identity: 23% (68 aa)

FSDKNVLGQGGFG-KVYKGSLEN---------------------------GKLVAVKRLRTD----------------------------QNISAGGEQA
.   . .|.|||| .||.. ...                           .. ||.| . .|                             .....   |
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FQT---EVEIIGLAVHRNLLRLDGFCITPSERILVYPFMPNGSVASRLRKLKINHL---K-TLDWETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANV
|..   || |.    | |.. | |||| |  ...|  ..|.|.  ..|.. | . .   |  ..| .. .|||  | |..|||  ..| ||||| |  |.
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LL---D---------KDFQAVVGDFGLAKLIDTKNTH-ITTNVRGTPGHIAPEYLSTG---KSSEKTDVFGYGVLMLELITGK-RAFD
||   .          .  | ..|||.  .  .  .. ..  . |.||  ||| .  .     .||.|.. .|... ||.|.. ..||
LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase LRR2_d.AA DRK 290-488 33 3.2e-27 89.29 In-house 4-197 (258) Show / Hide 
Range on Protein: 290-488
Range on HMM: 4-197/258
Sequence Identity: 33% (67 aa)

KNVLGQGGFGKVYKGSLENGKLVAVKRLRTDQNIS-AGGEQAFQTEVEIIGLAVHRNLLRLDGFCITPSERILVYPFMPNGSVASRLRKLKINHLKTLDW
 |  | |..| |. |.   |  ||||.|  . ||      . |. |....    | |     | |  |..   .  .|| || .. |   .|     .||
GNRIGRGNYGEVFRGTWR-GTQVAVKMLFNH-NINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIE----MDW

ETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLDKDFQAVVGDFGLAK-LIDTKNTHITTNVRGTPGHIAPEYLSTGKSSEKTDVFGYGVLMLELI
  .||... .| |. |||  | | ||||| |  | | |  .|  | ||||.      |    .    |||. .||| |      || ||. ...   |..
PLMKQMMFDCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV

T
|
T
Kinase LRR2_d.AA LISK 382-492 30 3.8e-23 71.89 In-house 94-238 (296) Show / Hide 
Range on Protein: 382-492
Range on HMM: 94-238/296
Sequence Identity: 30% (45 aa)

HLKTLDWETRKQIALGAAHGLRYLHVHCSPRIIHRDVKAANVLLD----KDFQAVVGDFGLAKLIDTKN-------------------------------
| . | |. |  |||. | |..|||   |  ||||| |. |.|..     .....|.|||.|...| .|                               
HKIPLPWPQRVKIALDIACGMSYLH---SMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCM

----THITTNVRGTPGHIAPEYLSTGKSSEKTDVFGYGVLMLELITGKRA
     . |  . |||   ||| |   . .|. ||| .|....|.||...|
NQRKRRMT--ICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA
Kinase LRR2_d.AA LISK 292-348 26 6.4e-08 21.61 In-house 1-60 (296) Show / Hide 
Range on Protein: 292-348
Range on HMM: 1-60/296
Sequence Identity: 26% (16 aa)

VLGQGGFGKVYKGSLE-NGKLVAVKRLRT--DQNISAGGEQAFQTEVEIIGLAVHRNLLR
..|.|.|||||||..   |. .|.| . .  .  .    .  .. ||... .  |.| ..
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQ
Kinase LRR2_d.AA IRAK 533-564 28 0.006883 6.27 In-house 286-317 (317) Show / Hide 
Range on Protein: 533-564
Range on HMM: 286-317/317
Sequence Identity: 28% (9 aa)

PNEVEKLTQIALLCTQASPSDRPKMVEVVSML
||..... | |. |. .    |..| .|.. |
PNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase LRR2_d.AA LRRK 545-566 31 0.007512 5.9 In-house 330-351 (351) Show / Hide 
Range on Protein: 545-566
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

LCTQASPSDRPKMVEVVSMLEG
.| |. | .||.. ..|. |. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR2_d.AA DRK 546-566 38 0.021948 3.93 In-house 238-258 (258) Show / Hide 
Range on Protein: 546-566
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CTQASPSDRPKMVEVVSMLEG
|    |. || | |..  || 
CWNEDPQHRPSMQECLERLEA
Kinase LRR2_d.AA MLK 546-564 31 0.022983 4.17 In-house 273-291 (291) Show / Hide 
Range on Protein: 546-564
Range on HMM: 273-291/291
Sequence Identity: 31% (6 aa)

CTQASPSDRPKMVEVVSML
| .. |..||.. ..|. |
CWNQDPHKRPSFRQIVQHL
Kinase LRR2_d.AA Pkinase_Tyr 537-564 25 0.024994 8.51 Pfam 243-270 (270) Show / Hide 
Range on Protein: 537-564
Range on HMM: 243-270/270
Sequence Identity: 25% (7 aa)

EKLTQIALLCTQASPSDRPKMVEVVSML
... .. ..| .. |.||| . |....|
DEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase LRR2_d.AA LISK 541-564 29 0.081939 1.44 In-house 273-296 (296) Show / Hide 
Range on Protein: 541-564
Range on HMM: 273-296/296
Sequence Identity: 29% (7 aa)

QIALLCTQASPSDRPKMVEVVSML
.... |.   |..||.  |.|. |
DLCFDCCKYDPKNRPSFKEIVQWL