Gene LRR2_c-1 (S.moellendorffii)

LRR2_c-1

Species: S.moellendorffii
Alias: LRR2_c-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR2

Sequence

Name Sequence Type Origin Length Description Download
LRR2_c-1.AA Protein None 660 None Fasta, JSON
LRR2_c-1.NA RNA None 1983 None Fasta, JSON
LRR2_c-1.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of LRR2_c-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR2_c-1.AA LRRNT_2 56-92 40 2.6e-13 46.16 Pfam 5-46 (46) Show / Hide 
Range on Protein: 56-92
Range on HMM: 5-46/46
Sequence Identity: 40% (17 aa)

VSALFAFKQSLV--DP-QNAMSGWDKNA--VDPCSWIHVSCS
. || |||.||.  ||  .. | |....  .|.|||  |.|.
GQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR2_c-1.AA LRR_1 136-158 51 4.3e-05 22.23 Pfam 1-26 (26) Show / Hide 
Range on Protein: 136-158
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

NLQYLMLQN-N--NLSGPIPPE-FGNW
|||.| |.. |  ||.| |||. | | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_c-1.AA LRR_1 160-182 33 0.004731 14.99 Pfam 1-26 (26) Show / Hide 
Range on Protein: 160-182
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RIISVDLSN-N--NLSDPIPST-LGKL
.. . |||. |  ||.. ||.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_c-1.AA LRR_1 184-206 33 0.056533 11.17 Pfam 1-26 (26) Show / Hide 
Range on Protein: 184-206
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

TLQYLRLNN-N--SLSGAFPVS-VATI
.||.| |.. |  .|.| .| |     
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_c-1.AA LRR_1 208-231 40 0.031106 12.09 Pfam 1-26 (26) Show / Hide 
Range on Protein: 208-231
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ALDFLDVSF-N--NLSGNVPNATTANL
 |  ||.|  |  ||.|..|. .  ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR2_c-1.AA TKL 342-610 21 1.9e-59 203.84 In-house 1-364 (364) Show / Hide 
Range on Protein: 342-610
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

LGRGGFGIVYKGTLPD---------GTPIAVKRLKEGSSNGGE------------------------YQFQMEVEMISLAV--HRNLLRLKGFCMTPTE-
.|.||||.||||..           |...|||..|. ...  .                        ..|. |.|. ..    | |.....|.|. |.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYPYMPNGSVASRLRDLICGKPALDWPTRKRIALGSARGLLYLHEHCD-----PKIIHRDVKAANILLDEDFE------------
              .|. |.|.||  ..|           |. | |.||. |||. ||| .       |.||||| | .|||.||...            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AVVGDFGLAKLLDHRESHVTTA------------------VRGTVGHIAPEYLS----------------TGQSSEKTDVFGFGILLLELITGQGAFD
  . ..||||.. ......   |.                  ..|| .. ||| |                  .. |||.||. |||.| |..|..  ..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

FNRLLTNKDV----MLLDWVKQLQHANNLD-----RLVDAELKGNYNAVELEEMVQVALLCTQMFPADRPKMSEVVRML
 .   . .      . . .| . ..   ..     ..   . .   .   ...| . .  | .. | .|| ..|..  |
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH---K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR2_c-1.AA IRAK 336-610 31 3.9e-58 199.47 In-house 1-317 (317) Show / Hide 
Range on Protein: 336-610
Range on HMM: 1-317/317
Sequence Identity: 31% (100 aa)

FDMKNILGRGGFGIVYKGTLPDGT-PIAVKRLKEG---SSNGGEYQFQM---EVEMISLAVHRNLLRLKGFCMTPTERLLVYPYMPNGSVASRLRDLICG
|.  | .| |||| ||.| .   | . |||.|||.   | |. . .||    |..  ..  | |.. | |.|  . .  ||||||||||   ||. .   
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

KP--ALDWPTRKRIALGSARGLLYLHEHCDPK--IIHRDVKAANILLDEDFEAVVGDFGLAKLL----DHRESHV----TTAVRGTVGHIAPEYLS--TG
 |  .| |..|. |..|.|.|. .||.  .|.  |||.|.| ||||||..|..  .||||.       .   . .    |  ||||    .||..   .|
CPPKPLSWHQRCSICWGTACGIQFLHQN-HPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

QSSEKTDVFGFGILLLELITGQGAFDFNRLLTNKDVMLLDWVKQLQHA--------------------NNL---DRLVDAELKGNYNAVELEEMVQVALL
| . ||||. ||| |||..||. | . .|  .   . |.. ...                        . .     ..| ....  . .. .|| |.|. 
QLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFID-HRMPPCPPNMEKEMCQCACC

CTQMFPADRPKMSEVVRML
|.    . |..| .|.  |
CGHHRANRRCDMAWVMQQL
Kinase LRR2_c-1.AA TK 336-610 17 2.9e-43 142.4 In-house 1-486 (486) Show / Hide 
Range on Protein: 336-610
Range on HMM: 1-486/486
Sequence Identity: 17% (84 aa)

FDMKNILGRGGFG---IVYKGTLPDG--------------------------TPIAVKRLKEGSSNGGEYQFQ-------------MEVEMISLAV----
  . . ||.| ||    ||||.. ..                          || ||| ||||...  | .|.             .|.|....      
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLLRLKGFCMTPTE------------RLLVYPYMPNGS----VASRLRDLICGKPA-----------------------------------------
 | |..|| | |. . .             ..|  |||.|.      . ||.   ..                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWPTRKRIALGSARGLLYLHEH----CDPKIIHRDVKAANILLDEDFE-----------AVVGDFG--
                               |. ...  ...  |.|. |||..      ....|||. | |.|..|.             . ..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LAKLLDHRESHVTTAVRGTV-------------------GH------IAPEYLS---------TGQSSEKTDVFGFGILLLELITGQGAFDFNR
      ||. .....  ...  .||                    |        ||| |          .|  ..|.||. ||.|. |. |  |.  .  
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT-YGQEPYYG

LLTNKDVML-------LDWVKQ--------LQHANNLDRLVDAELKGNYNAVEL----------EEMVQVALLCTQMFPADRPKMSEVVRML
 ..| ||.        .. ...        | . .  .|.  .  ..    . .          ||. .. . | .  |.||| .|.....|
GMSNQDVWKDGDNQEVMEYLRRGGRLCRSGL-N-EVGYRMRMPQPPHCPDWM-RYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR2_c-1.AA Dicty4 336-536 35 3.1e-39 128.61 In-house 1-214 (277) Show / Hide 
Range on Protein: 336-536
Range on HMM: 1-214/277
Sequence Identity: 35% (76 aa)

FDMKNILGRGGFGIVYKGTLPDGTPIAVKRL---KEGSSNGGEYQFQMEVEMISLAVHRNLLRLKGFCM----TPTERLLVYPYMPNGSVASRLRD---L
 .  ...|.|.|| |||||   |.  ||| |   .....      |  ||.  .   | |.. ..| |     .| . . |  ||| |...| |.|    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

ICGKPALDWPTRKR---IALGSARGLLYLHEHCDPKIIHRDVKAANILLDEDFEAVVGDFGLAKLLDHRESHVT--TAVRGTVGHIAPEYLSTGQSSEKT
   .  ||||..||   .|.  |||. .||. |.| ||||| |..|.| |... . |.||||...    |.| .  ... ||..  ||| .      || 
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVFGFGILLLELITGQ
||. |||.| |. |.|
DVYSFGIVLWEILTRQ
Kinase LRR2_c-1.AA TyrKc 336-610 25 2.9e-38 134.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 336-610
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

FDMKNILGRGGFGIVYKGTLPDGTPIAVKRLKEGSSNGGEYQFQMEVEMISLA--VHRNLLRLKGFCMTP-------TERLLVYPYMPNGSVASRLRDLI
  .. .||.| ||.|||||.   .. ||| |||..    .  |  | .. .     | |..|| | |...          ..|  |||.|.  ..||.  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

CGKPALDWPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANILLDEDFEAVVGDFGLAKLLDHR----ESHVTTAVRGTVGHI--------APEYLSTG
     | ...   ...  |.|  |||..   ..||||  | |.|..|.. . ..||||.. ...     ||. .  .... |          ||| . .|
PK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

QSSEKTDVFGFGILLLELITGQGAFDFNRL----LTNKDVMLLDWVKQLQHANNLDRLVDAELKGNYNAV----ELEEMVQVALLCTQMFPADRPKMSEV
  ..|.||. ||... |. |  |.          ..|..|.     ..... . ...  ...       .      .|| |. . | .  |.||| .||.
KFTTKSDVWSFGVCMWEIFT-YGQQPYPGMIQQMMSNQEVI-----EYVKQGYRMPQPPNDY-----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

VRML
.. .
HECF
Kinase LRR2_c-1.AA Pkinase 336-536 26 6.1e-38 135.24 Pfam 1-209 (293) Show / Hide 
Range on Protein: 336-536
Range on HMM: 1-209/293
Sequence Identity: 26% (57 aa)

FDMKNILGRGGFGIVYKGTLPDG-TPIAVKRLKEGSSNGGE-YQFQM--EVEMISLAVHRNLLRLKGFCMTPTERLLVYPYMPNG-SVASRLRDLIC--G
.  . ..|.|.|| |||..  .     |||..|  . . .. ..     |...     | | .||.........  .| .|...| .    | |.|    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

KPAL--DWPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANILLDEDFEA----VVGDFGLAKLLDHRESHVTTAVRGTVGHIAPEYLS-TGQSSEKTD
. ..  .. . |....  .||| |.|..   .|||||.| .|||.|.. .      ..||||||..|.  .. .| . || . .||| .      . | |
HGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VFGFGILLLELITGQ
....|..| |...|.
MWSCGCILYEMLCGR
Kinase LRR2_c-1.AA S_TKc 336-610 21 1.5e-34 122.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 336-610
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

FDMKNILGRGGFGIVYKGTLPD-GTPIAVKRLKEGSSNGGEYQFQMEVEMISLAVHRNLLRLKGFCMTPTERLLVYPYMPN--GSVASRLRDLICGKPA-
... ...|.|.|| |||..  . |   |.|..|         ... |... .   | |. .|.... . ..  .|  |...  |.. .....  ....  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDWPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANILLDEDFEAVVGDFGLAKLLDHRESHVTTAVRGTVGHIAPEYLSTGQSSE-KTDVFGFGILL
 ..  . ....   ...| |.|.|    |||||.| .||||||  .  ..|||||..|        | . ||   .||| |   . .  | |.  .|..|
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LELITGQGAFDFNRLLTNKDVMLLDWVKQLQHANNLDRLVDAELKGNYNAVELEEMVQVALLCTQMFPADRPKMSEVVR---------ML
 |...|.  |.        . |... ..                         .|. .    | |. |..||   |. .          .
YEMLCGYPPFP-------QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR2_c-1.AA Pkinase_Tyr 336-534 30 3.3e-34 116.47 Pfam 1-209 (270) Show / Hide 
Range on Protein: 336-534
Range on HMM: 1-209/270
Sequence Identity: 30% (65 aa)

FDMKNILGRGGFGIVYKGTLP-----DGTPIAVKRLKEGSSNGG--EYQFQMEVEMISLA-VHRNLLRLKGFCMTPTER---LLVYPYMPNGSVASRLRD
  .   ||.| || |||||.      ...| ||| ||||..        |  |... .    | |..|| | |.   |    ..| .|||.|.  . ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

LICGKPALDWPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANILLDEDFEAVVGDFGLAKLLDHRESH-VTTA-----VRGTVGHIAPEYLSTGQSSE
   .|..|. ..   ...  |.|. ||...    .||||. | |.|..|.. . ..|||||... . .   ...      .. .    ||| ...|  ..
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFTT

KTDVFGFGILLLELIT
|.||  ||.|. |..|
KSDVWSFGVLMWEIFT
Kinase LRR2_c-1.AA MLK 336-536 26 1.3e-33 114.06 In-house 1-233 (291) Show / Hide 
Range on Protein: 336-536
Range on HMM: 1-233/291
Sequence Identity: 26% (62 aa)

FDMKNILGRGGFGIVYKGTLPDGTP-----IAVKRLK-----EGSSNGGEYQFQMEVEMISLAVHRN----LLRLKGFCMTPTE-RLLVYPYMPNGSVAS
.. . ..| |.|| |.||.   ..      .|||| .      ...     .|.||..  .   |.|      ...| |  |.   ..|  |...|| ..
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

RLRD-LICGKPA---------LDWPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANILLDE------DFEAVVGDFGLAKLLDHRESHVTTAVRGTVG
 |..  . . .|          |     ..||  |||. |||..  ..||||| |  |||.||      .  ... |||... . ...    .  .||. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

HIAPEYL---STGQSSEKTDVFGFGILLLELITGQ
  ||| .     .. ||| ||. .|..| |..|..
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase LRR2_c-1.AA LRRK 336-540 25 2.9e-32 111.42 In-house 1-284 (351) Show / Hide 
Range on Protein: 336-540
Range on HMM: 1-284/351
Sequence Identity: 25% (72 aa)

FDMKNILGRGGFG-IVYKGTLPD---------------------------GTPIAVKRLKEG---------SSNG-----------------------GE
.   . .|||||| .||.... .                           ....|.| .. .         .||.                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YQ-FQMEVEMISLAVHRNLLRLKGFCMTPTERLLVYPYMPNGSVASRLRDLICGK-----PALDWPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANI
.. |. || ..|   | |.. |||||. |  . .|  |.|.|.  ..|..    .     . ..| .. .|||  |.|. ||| | .|.||||| |  ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH-NPPIIHRDLKSPNI

LL---D---------EDFEAVVGDFGLAKLLDHRESHVTTAVRGTVGHIAPEYLSTG---QSSEKTDVFGFGILLLELITGQ-GAFD
||   .         ..  | ..|||.  .     . |.  . |. |  ||| .  .   . .||.|.. ||..| ||.|.|  .||
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase LRR2_c-1.AA DRK 336-534 35 4e-32 106.12 In-house 1-197 (258) Show / Hide 
Range on Protein: 336-534
Range on HMM: 1-197/258
Sequence Identity: 35% (71 aa)

FDMKNILGRGGFGIVYKGTLPDGTPIAVKRLKEGSSN--GGEYQFQMEVEMISLAVHRNLLRLKGFCMTPTERLLVYPYMPNGSVASRLRDLICGKPALD
    |  |||..| |. ||   || .|||.|.    |       |. |.....   | |     | |  | . . .  ||| || .. | |       .|
IKIGNRIGRGNYGEVFRGTW-RGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESI---EMD

WPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANILLDEDFEAVVGDFGLAK-LLDHRESHVTTAVRGTVGHIAPEYLSTGQSSEKTDVFGFGILLLEL
|| .|....  |.|. |||  |.| ||||| |  | | || .   | ||||.     |..   .    || . .||| |      || ||. |.| | |.
WPLMKQMMFDCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWEC

IT
.|
VT
Kinase LRR2_c-1.AA TKL-Unique 338-536 32 3.4e-31 107.31 In-house 1-225 (290) Show / Hide 
Range on Protein: 338-536
Range on HMM: 1-225/290
Sequence Identity: 32% (75 aa)

MKNILGRGGFGIVYKGTLPDGTPIAVKRLK--EGSSNGGEYQFQMEVEMISLAV-HRNLLRLKGFCM----TPTERLLVYPYMPNGSVASRLRDLIC---
  | .|.||.| ||||. . |.|.|.|...  |.|||  .  | .||  ..    | |.... |.||    .| .. .|  |.| ||    |.|..    
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGS----LYDVLHQNN

-------GKPALDWPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANILLDED-----FEAVVGDFGLAKLLDHR-ESHVT-------TAVRGTVGHIA
        .  |..  | ..|.  |.|. ||| ||.|.||||| |  |.|.|..     . . . ||||.|... . .. ..       . . |.   .|
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLH-HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMA

PEYLST--GQSSEKTDVFGFGILLLELITGQ
|| |.    | ||| ||. ||| | |..|..
PEVLRMNFCQYSEKSDVYSFGIVLWEIATRK
Kinase LRR2_c-1.AA STE 336-536 21 7.4e-31 106.23 In-house 1-265 (359) Show / Hide 
Range on Protein: 336-536
Range on HMM: 1-265/359
Sequence Identity: 21% (59 aa)

FDMKNILGRGGFGIVYKGTLPD----------------GTPIAVKRLKEGSSN---------------GGEY-QFQMEVEMISLAV--HRNLLRLKGFCM
..   ..|.|.|| |||.   .                |. .|.|...  ..|                 |  |...|... .     | |  .  | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TP-------TERLLVYPYMPNGSVASRLR-DLICGKP---------ALDWPTRKRIALGSARG-LLYLHEHCDPKIIHRDVKAANILLDEDFEAVVGDFG
         .|  ..  ||..||. . ..   .||||          .. .  ..|.    .| | |||.|    |||||.|.|||||     .   |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LAKLLDH---------------RESHVTTAVRGTVGHIAPEYLST------GQSSEKTDVFGFGILLLELITGQ
... |..                 .  .. . ||  . ||| ..       .. ..| |.  .|....|..||.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LRR2_c-1.AA LISK 422-535 30 6.8e-24 74.35 In-house 84-235 (296) Show / Hide 
Range on Protein: 422-535
Range on HMM: 84-235/296
Sequence Identity: 30% (48 aa)

LRDLICGKP----ALDWPTRKRIALGSARGLLYLHEHCDPKIIHRDVKAANILLD----EDFEAVVGDFGLAKLLDHRE---------------------
|....  ..     | || | .|||. |.|. |||. .   ||||| |. |.|..    ......|.|||.|...| ..                     
LHQYLKDMDKHKIPLPWPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMP

--------------SHVTTAVRGTVGHIAPEYLSTGQS-SEKTDVFGFGILLLELITG
              .. |  . ||    ||| | .||| .|. ||| |||.|.|.||.
MKRKIPKKCMNQRKRRMT--ICGTPYWMAPEML-LGQSYDESCDVFSFGIVLCEIITR
Kinase LRR2_c-1.AA LISK 341-395 35 2.2e-09 26.43 In-house 1-60 (296) Show / Hide 
Range on Protein: 341-395
Range on HMM: 1-60/296
Sequence Identity: 35% (21 aa)

ILGRGGFGIVYKGTLP-DGTPIAVKRLKE--GSSNGGEYQ--FQMEVEMISLAVHRNLLR
..|.|.|| |||||.  .|...|.| ...    .|  |||  .. ||.|. .  |.| ..
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQ
Kinase LRR2_c-1.AA LISK 586-610 28 0.006844 5.0 In-house 272-296 (296) Show / Hide 
Range on Protein: 586-610
Range on HMM: 272-296/296
Sequence Identity: 28% (7 aa)

VQVALLCTQMFPADRPKMSEVVRML
..... |. . | .||. .|.|. |
LDLCFDCCKYDPKNRPSFKEIVQWL
Kinase LRR2_c-1.AA MLK 597-610 35 0.016564 4.67 In-house 278-291 (291) Show / Hide 
Range on Protein: 597-610
Range on HMM: 278-291/291
Sequence Identity: 35% (5 aa)

PADRPKMSEVVRML
|..||.....|  |
PHKRPSFRQIVQHL
Kinase LRR2_c-1.AA DRK 597-612 43 0.045259 2.85 In-house 243-258 (258) Show / Hide 
Range on Protein: 597-612
Range on HMM: 243-258/258
Sequence Identity: 43% (7 aa)

PADRPKMSEVVRMLEG
|  || | |..  || 
PQHRPSMQECLERLEA
Kinase LRR2_c-1.AA Pkinase_Tyr 597-610 50 0.114611 6.27 Pfam 257-270 (270) Show / Hide 
Range on Protein: 597-610
Range on HMM: 257-270/270
Sequence Identity: 50% (7 aa)

PADRPKMSEVVRML
|.||| .||....|
PEDRPTFSEIHEQL
Kinase LRR2_c-1.AA LRRK 591-612 36 0.159343 1.14 In-house 330-351 (351) Show / Hide 
Range on Protein: 591-612
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

LCTQMFPADRPKMSEVVRMLEG
.| |  | .||..|..|  |. 
HCWQHDPKKRPHFSQIVKRLSQ