Gene LRR2_a-1 (S.moellendorffii)

LRR2_a-1

Species: S.moellendorffii
Alias: LRR2_a-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR2

Sequence

Name Sequence Type Origin Length Description Download
LRR2_a-1.AA Protein None 602 None Fasta, JSON
LRR2_a-1.NA RNA None 1809 None Fasta, JSON
LRR2_a-1.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of LRR2_a-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR2_a-1.AA LRRNT_2 1-37 40 2.5e-13 46.2 Pfam 5-46 (46) Show / Hide 
Range on Protein: 1-37
Range on HMM: 5-46/46
Sequence Identity: 40% (17 aa)

GDALHVFRQALD--DP-SNVLQSWDPTL--VNPCTWFHVTCN
|.||  |...|.  || ..||.||.|.   ...|.|  |||.
GQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR2_a-1.AA LRR_1 41-63 25 16.160788 2.46 Pfam 1-26 (26) Show / Hide 
Range on Protein: 41-63
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

NVIRVDLGN-A--FLSGRLVAA-LGNL
|  . ||..     |.| .    . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_a-1.AA LRR_1 65-87 48 5.5e-05 21.85 Pfam 1-26 (26) Show / Hide 
Range on Protein: 65-87
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

NLQYLELYS-N--NITGPIPKE-LGNL
|||.| | . |  |.|| ||.. . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_a-1.AA LRR_1 89-111 40 0.001069 17.28 Pfam 1-26 (26) Show / Hide 
Range on Protein: 89-111
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ELVSLDLYQ-N--SFTGDIPDS-LGKL
 | .|||   |  ..||.||.| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_a-1.AA LRR_1 113-135 37 0.076214 10.71 Pfam 1-26 (26) Show / Hide 
Range on Protein: 113-135
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLRFLRLNN-N--TLDGKIPNS-LTTI
||. | |.. |   | |.||.| .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR2_a-1.AA LRR_1 137-161 42 0.002346 16.07 Pfam 1-26 (26) Show / Hide 
Range on Protein: 137-161
Range on HMM: 1-26/26
Sequence Identity: 42% (12 aa)

GLQVLDLSN-N--NLSGPVPTNGSFSLF
 ||.||||. |  ||.| .| . .|  .
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
Kinase LRR2_a-1.AA IRAK 278-552 30 3.5e-65 222.87 In-house 1-317 (317) Show / Hide 
Range on Protein: 278-552
Range on HMM: 1-317/317
Sequence Identity: 30% (97 aa)

FNNRNILGRGGFGKVYKGRLADGS-LVAVKRLKEERSP---GGELQFQT---EVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMPNGSVASRLRERLPG
|.  | .| |||| ||.|..      .|||.|||....   . . .||.   |..  .   | |.. | |.|  . .  ||||||||||   ||. . . 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

DTP--LDWPTRKCIALGAARGLSYLHDHCDPK--IIHRDVKAANILLDEEYEAVVGDFGLAKLM----DYKDTHV----TTAVRGTIGHIAPEYLS--TG
..|  | |..|. |..|.|.|. .||.  .|.  |||.|.| ||||||.  ..  .||||.       . ... .    |  ||||    .||..   .|
CPPKPLSWHQRCSICWGTACGIQFLHQN-HPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

KSSEKTDVFGFGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLRE--------------------RKV---DLLVDPDLKNEYDPMEVEQLIQVALL
. . ||||. ||| |||..||.|| .  |  .   . |.. ..   .                     |..    ...|. ...  .| ... . |.|. 
QLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDH-RMPPCPPNMEKEMCQCACC

CTQGSPMDRPKMAEVVRML
|. .    |..||.|.  |
CGHHRANRRCDMAWVMQQL
Kinase LRR2_a-1.AA TKL 284-552 23 2.3e-63 216.84 In-house 1-364 (364) Show / Hide 
Range on Protein: 284-552
Range on HMM: 1-364/364
Sequence Identity: 23% (88 aa)

LGRGGFGKVYKGRLAD---------GSLVAVKRLKEERSPGGE------------------------LQFQTEVEMISMAV--HRNLLRLRGFCMTPTE-
.|.||||.||||..           |  ||||..|.. .   .                        ..|. |.|. .|    | |.... |.|. |.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYPYMPNGSVASRLRERLPGDTPLDWPTRKCIALGAARGLSYLHDHCD-----PKIIHRDVKAANILLDEEYE------------
              .|. |.|.||  ..|           |. |  .||..|||..||| .       |.||||| | .|||.|| ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AVVGDFGLAKLM----DYKDTHVTTA--------------VRGTIGHIAPEYLS----------------TGKSSEKTDVFGFGIMLLELITGQRAFD
  . ..||||.. |    . .||  |.               ..||... ||| |                  .. |||.||. |||.| |..|..| ..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

--LARLANDDDVMLLDWVKGLLRERKVDLLVDPDLKN----EYDPMEVEQLIQVALLCTQGSPMDRPKMAEVVRML
    .     |   ...   .  ...  ....|  .|       |   ..... .  | .  | .|| . |..  |
DYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR2_a-1.AA Pkinase 278-478 26 8e-45 159.56 Pfam 1-209 (293) Show / Hide 
Range on Protein: 278-478
Range on HMM: 1-209/293
Sequence Identity: 26% (58 aa)

FNNRNILGRGGFGKVYKGRLADGSL-VAVKRLKEERSPGGELQFQT---EVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMPNG----SVASRLR-ERL
.    ..|.|.||.|||..  . .  ||||..| ..   ...|  .   |...  .  | | .||.........  .| .|...|    . ..... .| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR-

PGDTPL--DWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEA----VVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLS-TGKSSEK
  ....  .. . |....  .||| |.|..   .|||||.| .|||.|....      ..||||||..||   . .| . ||.. .||| .    . . |
--HGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

TDVFGFGIMLLELITGQ
 |....|..| |...|.
VDMWSCGCILYEMLCGR
Kinase LRR2_a-1.AA TK 278-476 17 1.2e-42 140.29 In-house 1-389 (486) Show / Hide 
Range on Protein: 278-476
Range on HMM: 1-389/486
Sequence Identity: 17% (70 aa)

FNNRNILGRGGFG---KVYKGRLADGS--------------------------LVAVKRLKEERSPGGELQFQ-------------TEVEMISMAV----
    . ||.| ||   .||||.. ...                           |||| |||. .   | .|.              |.|...|      
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLLRLRGFCMTPTE------------RLLVYPYMPNGS----VASRLRERLPGDTP-----------------------------------------
 | |..|| | |. . .             ..|  |||.|.      . ||.. |. ..                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWPTRKCIALGAARGLSYLHDH----CDPKIIHRDVKAANILLDEEYE-----------AVVGDFG--
                               |. ...  ... .|.|..|||..      ....|||. | |.|..|..            . ..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LAKLMDYKDTHVTTAVRGTI-------------------GH------IAPEYLS---------TGKSSEKTDVFGFGIMLLELIT
      ||. ....|  ...  .||                    |        ||| |          .|| ..|.||. ||... |. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase LRR2_a-1.AA Pkinase_Tyr 278-476 29 4.5e-38 129.57 Pfam 1-209 (270) Show / Hide 
Range on Protein: 278-476
Range on HMM: 1-209/270
Sequence Identity: 29% (65 aa)

FNNRNILGRGGFGKVYKGRLA-----DGSLVAVKRLKEERSPGG--ELQFQTEVEMISMA-VHRNLLRLRGFCMTPTER---LLVYPYMPNGSVASRLRE
      ||.| ||.||||..      ..  |||| |||  ..       |  |... .    | |..|| | |.   |    ..| .|||.|.  . ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

-RLPGDTPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAKLMDYKDTH-VTTA-----VRGTIGHIAPEYLSTGKSS
 | ... ||. ..  ....  |.|..||...    .||||. | |.|..|.  . ..|||||...  .|.  ...      .. .    ||| ...|| .
HR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFT

EKTDVFGFGIMLLELIT
.|.||  ||. . |..|
TKSDVWSFGVLMWEIFT
Kinase LRR2_a-1.AA S_TKc 278-552 22 2.3e-37 131.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 278-552
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

FNNRNILGRGGFGKVYKGRLAD-GSLVAVKRLKEERSPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMPN--GSVASRLRERLPGDTP-
.   ...|.|.||||||.|  . | .||.|..|         ... |... ..  | |. .| ... . ..  .|  |...  |.. .....| .. .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGFGIMLL
 ..  . ....   ...| |.|.|    |||||.| .||||||  .  ..|||||...        | . ||   .||| |  | . .| |.  .|..| 
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

ELITGQRAFDLARLANDDDVMLLDWVKGLLRERKVDLLVDPDLKNEYDPMEVEQLIQVALLCTQGSPMDRPKMAEVVR---------ML
|...|.  |.       .. |... ..                         .....    | |  | .||   |. .          .
EMLCGYPPFP-------QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR2_a-1.AA Dicty4 278-478 35 2.9e-37 121.93 In-house 1-214 (277) Show / Hide 
Range on Protein: 278-478
Range on HMM: 1-214/277
Sequence Identity: 35% (77 aa)

FNNRNILGRGGFGKVYKGRLADGSLVAVKRL--KEERSPGGELQ-FQTEVEMISMAVHRNLLRLRGFCM----TPTERLLVYPYMPNGSVASRLRE---R
 |  ...|.|.||.||||.   |. |||| |  . . .   .|. |  ||.  .   | |.. . | |     .| . . |  ||| |...| |.     
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

LPGDTPLDWPTRKC---IALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAKLMDYKDTHVT--TAVRGTIGHIAPEYLSTGKSSEKT
    ..||||..|    .|. ||||. .||  |.| ||||| |..|.| |. . . |.||||...|    .| .  ... || .  ||| .      || 
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVFGFGIMLLELITGQ
||. |||.| |. |.|
DVYSFGIVLWEILTRQ
Kinase LRR2_a-1.AA MLK 278-478 27 7.3e-36 121.93 In-house 1-233 (291) Show / Hide 
Range on Protein: 278-478
Range on HMM: 1-233/291
Sequence Identity: 27% (65 aa)

FNNRNILGRGGFGKVYKGRLADGSL-----VAVKRLK--EERSPGGE----LQFQTEVEMISMAVHRN----LLRLRGFCMTPTE-RLLVYPYMPNGSVA
...  ..| |.||||.|||   . .     ||||| .   . . . .     .|..|..  ..  |.|      ...| |  |.   ..|  |...|| .
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

SRLRERLP----------GDTPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDE------EYEAVVGDFGLAKLMDYKDTHVTTAVRGTI
. |... .           |   |      .||  |||..||| .  ..||||| |  |||.||      .  ... |||... .  ..    .  .|| 
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTY

GHIAPEYL---STGKSSEKTDVFGFGIMLLELITGQ
   ||| .     .| ||| ||. .|..| |..|..
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase LRR2_a-1.AA TyrKc 278-552 25 4.4e-35 123.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 278-552
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

FNNRNILGRGGFGKVYKGRLADGSLVAVKRLKEERSPGGELQFQTEVEMISMA--VHRNLLRLRGFCMTP-------TERLLVYPYMPNGSVASRLRERL
     .||.| ||.||||..     |||| |||.     .  |  | .. ..    | |..|| | |...          ..|  |||.|.  ..||.. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

PGDTPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAKLMDYK-------DTHVTT---AVR--GTIGHIAPEYLSTG
|    | ...   ... .|.| .|||..   ..||||  | |.|..|.. . ..||||..  . .       |. ...     .    |   ||| . .|
PK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KSSEKTDVFGFGIMLLELITGQRAFDLARLANDDDV---MLLDWVKGLLRERKVDLLVDPDLKNEYDPM----EVEQLIQVALLCTQGSPMDRPKMAEVV
| ..|.||. ||... |. |      .      ...   |  . |  ......     . |.     ||      . . |. . | .  | ||| ..|..
KFTTKSDVWSFGVCMWEIFT------YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

RML
. .
ECF
Kinase LRR2_a-1.AA STE 278-478 20 1.1e-33 116.35 In-house 1-265 (359) Show / Hide 
Range on Protein: 278-478
Range on HMM: 1-265/359
Sequence Identity: 20% (55 aa)

FNNRNILGRGGFGKVYKGRLAD----------------GSLVAVKRLKEERS----------------PGGELQFQTEVEMISMAV--HRNLLRLRGFCM
. .  ..|.|.||.|||..  .                | ..|.|... |..                .  . |.. |... .     | |  .  | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TP-------TERLLVYPYMPNGSVASRLRERLPGDTPLD----------WPTRKCIALGAARG-LSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFG
         .|  ..  ||..||. . ....     ||.           .  ..|.    .| |.|||.|    |||||.|.|||||     .   |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LAKLMDYK--------------DTH-VTTAVRGTIGHIAPEYLST------GKSSEKTDVFGFGIMLLELITGQ
... .. .              ..   .. . ||  . ||| ..       .. ..| |.  .|....|..||.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LRR2_a-1.AA DRK 285-476 34 5.9e-32 105.53 In-house 8-197 (258) Show / Hide 
Range on Protein: 285-476
Range on HMM: 8-197/258
Sequence Identity: 34% (67 aa)

GRGGFGKVYKGRLADGSLVAVKRLKEERSPGGEL--QFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMPNGSVASRLRERLPGDTPLDWPTRKCI
|||..| |. |    |. ||||.|.       ..   |. |.....   | |     | |  | . . .  ||| || .. | .       .||| .| .
GRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDE---SIEMDWPLMKQM

ALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAK-LMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGFGIMLLELIT
.. .|.|. |||  |.| ||||| |  | | || .   | ||||.      |.   .    || . .||| |      || ||. |.| | |..|
MFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT
Kinase LRR2_a-1.AA TKL-Unique 282-479 31 2.7e-31 107.66 In-house 3-226 (290) Show / Hide 
Range on Protein: 282-479
Range on HMM: 3-226/290
Sequence Identity: 31% (72 aa)

NILGRGGFGKVYKGRLADGSLVAVKRLK-EERSPGGELQ-FQTEVEMISMAV-HRNLLRLRGFCM----TPTERLLVYPYMPNGSVASRLRERLPGD---
| .|.||.|.||||  . |. ||.|... .| |   ..| |  ||  ...   | |.... |.||    .| .. .|  |.| ||  . |   ..     
NKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

---TPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEE-----YEAVVGDFGLAKLMDYKDTHVTT--------AVRGTIGHIAPEYLST
   ..|..  |  .|. .|.|. ||| ||.|.||||| |  |.|.|..     . . . ||||.|. .  ..  ..         . |..  .||| |. 
NNNCKLNMQQRVKMAIDIAQGMYYLH-HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GKSSEKTDVFGFGIMLLELITGQR
   . ||| ||. |||.| |..|...
NFCQYSEKSDVYSFGIVLWEIATRKI
Kinase LRR2_a-1.AA LISK 364-480 32 1.1e-24 77.02 In-house 84-238 (296) Show / Hide 
Range on Protein: 364-480
Range on HMM: 84-238/296
Sequence Identity: 32% (51 aa)

LRERLP-GDT---PLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEE----YEAVVGDFGLAKLMDYKDTH-------------------
|...|   |    || || |  |||. |.|.||||. .   ||||| |. |.|..|     ....|.|||.|..|| ..                     
LHQYLKDMDKHKIPLPWPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMP

--------------VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGFGIMLLELITGQRA
               . .. ||    ||| |   . .|. ||| |||.|.|.||. .|
MKRKIPKKCMNQRKRRMTICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA
Kinase LRR2_a-1.AA LRRK 332-482 32 1.2e-24 84.12 In-house 116-284 (351) Show / Hide 
Range on Protein: 332-482
Range on HMM: 116-284/351
Sequence Identity: 32% (56 aa)

HRNLLRLRGFCMTPTERLLVYPYMPNGSVASRLRERLPGD-----TPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILL---D---------
| |.. | |||. |  . .|  |.|.|.  ..|...         . ..| ..  |||  |.|. |||.| .|.||||| |  ||||   .         
HPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH-NPPIIHRDLKSPNILLWSSPQNHSPNYPN

EEYEAVVGDFGLAKLMDYKDTH-VTTAVRGTIGHIAPEYLSTG---KSSEKTDVFGFGIMLLELITGQ-RAFD
... | ..|||.   | . ... |.  . |..|  ||| .  .     .||.|.. ||. | ||.|.| ..||
AHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase LRR2_a-1.AA LISK 283-337 30 5.8e-09 25.05 In-house 1-60 (296) Show / Hide 
Range on Protein: 283-337
Range on HMM: 1-60/296
Sequence Identity: 30% (18 aa)

ILGRGGFGKVYKGRLA-DGSLVAVKRLKEE----RSPGGELQFQTEVEMISMAVHRNLLR
..|.|.|||||||..  .|. .|.| ...       |  .  .. ||.|. .  |.| ..
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQ
Kinase LRR2_a-1.AA LRRK 278-309 18 3.6e-07 21.39 In-house 1-60 (351) Show / Hide 
Range on Protein: 278-309
Range on HMM: 1-60/351
Sequence Identity: 18% (11 aa)

FNNRNILGRGGFG-KVYKGRLAD---------------------------GSLVAVKRLK
.   . .|||||| .||.... .                           .. ||.| ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWN
Kinase LRR2_a-1.AA TK 521-552 21 0.001034 7.47 In-house 455-486 (486) Show / Hide 
Range on Protein: 521-552
Range on HMM: 455-486/486
Sequence Identity: 21% (7 aa)

PMEVEQLIQVALLCTQGSPMDRPKMAEVVRML
... | . .. . | .  | ||| .......|
HCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR2_a-1.AA LRRK 533-554 31 0.025264 4.01 In-house 330-351 (351) Show / Hide 
Range on Protein: 533-554
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

LCTQGSPMDRPKMAEVVRMLEG
.| |. | .||.. ..|  |. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR2_a-1.AA DRK 534-554 38 0.068569 2.23 In-house 238-258 (258) Show / Hide 
Range on Protein: 534-554
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CTQGSPMDRPKMAEVVRMLEG
|    |  || | |..  || 
CWNEDPQHRPSMQECLERLEA
Kinase LRR2_a-1.AA MLK 539-552 35 0.102987 1.88 In-house 278-291 (291) Show / Hide 
Range on Protein: 539-552
Range on HMM: 278-291/291
Sequence Identity: 35% (5 aa)

PMDRPKMAEVVRML
| .||.....|  |
PHKRPSFRQIVQHL
Kinase LRR2_a-1.AA LISK 525-552 25 0.109822 1.02 In-house 269-296 (296) Show / Hide 
Range on Protein: 525-552
Range on HMM: 269-296/296
Sequence Identity: 25% (7 aa)

EQLIQVALLCTQGSPMDRPKMAEVVRML
........ |.   | .||. .|.|. |
PPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase LRR2_a-1.AA Pkinase_Tyr 532-552 33 3.455054 1.26 Pfam 250-270 (270) Show / Hide 
Range on Protein: 532-552
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

LLCTQGSPMDRPKMAEVVRML
..| .  | ||| ..|....|
KQCWHYDPEDRPTFSEIHEQL