LRR2_a-1

Species: S.moellendorffii
Alias: LRR2_a-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR2

Sequence

Name Sequence Type Origin Length Description Download
LRR2_a-1.AA Protein None 602 None Fasta, JSON
LRR2_a-1.NA RNA None 1809 None Fasta, JSON
LRR2_a-1.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of LRR2_a-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR2_a-1.AA LRRNT_2 1-37 40 2.5e-13 46.2 Pfam 5-46 (46) Show / Hide
Range on Protein: 1-37
Range on HMM: 5-46/46
Sequence Identity: 40% (17 aa)

GDALHVFRQALD--DP-SNVLQSWDPTL--VNPCTWFHVTCN
|.||  |...|.  || ..||.||.|.   ...|.|  |||.
GQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD

LRR_1 LRR2_a-1.AA LRR_1 41-63 25 16.160788 2.46 Pfam 1-26 (26) Show / Hide
Range on Protein: 41-63
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

NVIRVDLGN-A--FLSGRLVAA-LGNL
|  . ||..     |.| .    . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR2_a-1.AA LRR_1 65-87 48 5.5e-05 21.85 Pfam 1-26 (26) Show / Hide
Range on Protein: 65-87
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

NLQYLELYS-N--NITGPIPKE-LGNL
|||.| | . |  |.|| ||.. . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR2_a-1.AA LRR_1 89-111 40 0.001069 17.28 Pfam 1-26 (26) Show / Hide
Range on Protein: 89-111
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ELVSLDLYQ-N--SFTGDIPDS-LGKL
 | .|||   |  ..||.||.| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR2_a-1.AA LRR_1 113-135 37 0.076214 10.71 Pfam 1-26 (26) Show / Hide
Range on Protein: 113-135
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLRFLRLNN-N--TLDGKIPNS-LTTI
||. | |.. |   | |.||.| .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR2_a-1.AA LRR_1 137-161 42 0.002346 16.07 Pfam 1-26 (26) Show / Hide
Range on Protein: 137-161
Range on HMM: 1-26/26
Sequence Identity: 42% (12 aa)

GLQVLDLSN-N--NLSGPVPTNGSFSLF
 ||.||||. |  ||.| .| . .|  .
NLQHLDLSGCNCCNLTGHIPPS-CF-NL

Kinase LRR2_a-1.AA IRAK 278-552 30 3.5e-65 222.87 In-house 1-317 (317) Show / Hide
Range on Protein: 278-552
Range on HMM: 1-317/317
Sequence Identity: 30% (97 aa)

FNNRNILGRGGFGKVYKGRLADGS-LVAVKRLKEERSP---GGELQFQT---EVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMPNGSVASRLRERLPG
|.  | .| |||| ||.|..      .|||.|||....   . . .||.   |..  .   | |.. | |.|  . .  ||||||||||   ||. . . 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

DTP--LDWPTRKCIALGAARGLSYLHDHCDPK--IIHRDVKAANILLDEEYEAVVGDFGLAKLM----DYKDTHV----TTAVRGTIGHIAPEYLS--TG
..|  | |..|. |..|.|.|. .||.  .|.  |||.|.| ||||||.  ..  .||||.       . ... .    |  ||||    .||..   .|
CPPKPLSWHQRCSICWGTACGIQFLHQN-HPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

KSSEKTDVFGFGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLRE--------------------RKV---DLLVDPDLKNEYDPMEVEQLIQVALL
. . ||||. ||| |||..||.|| .  |  .   . |.. ..   .                     |..    ...|. ...  .| ... . |.|. 
QLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDH-RMPPCPPNMEKEMCQCACC

CTQGSPMDRPKMAEVVRML
|. .    |..||.|.  |
CGHHRANRRCDMAWVMQQL

Kinase LRR2_a-1.AA TKL 284-552 23 2.3e-63 216.84 In-house 1-364 (364) Show / Hide
Range on Protein: 284-552
Range on HMM: 1-364/364
Sequence Identity: 23% (88 aa)

LGRGGFGKVYKGRLAD---------GSLVAVKRLKEERSPGGE------------------------LQFQTEVEMISMAV--HRNLLRLRGFCMTPTE-
.|.||||.||||..           |  ||||..|.. .   .                        ..|. |.|. .|    | |.... |.|. |.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYPYMPNGSVASRLRERLPGDTPLDWPTRKCIALGAARGLSYLHDHCD-----PKIIHRDVKAANILLDEEYE------------
              .|. |.|.||  ..|           |. |  .||..|||..||| .       |.||||| | .|||.|| ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AVVGDFGLAKLM----DYKDTHVTTA--------------VRGTIGHIAPEYLS----------------TGKSSEKTDVFGFGIMLLELITGQRAFD
  . ..||||.. |    . .||  |.               ..||... ||| |                  .. |||.||. |||.| |..|..| ..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

--LARLANDDDVMLLDWVKGLLRERKVDLLVDPDLKN----EYDPMEVEQLIQVALLCTQGSPMDRPKMAEVVRML
    .     |   ...   .  ...  ....|  .|       |   ..... .  | .  | .|| . |..  |
DYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LRR2_a-1.AA Pkinase 278-478 26 8e-45 159.56 Pfam 1-209 (293) Show / Hide
Range on Protein: 278-478
Range on HMM: 1-209/293
Sequence Identity: 26% (58 aa)

FNNRNILGRGGFGKVYKGRLADGSL-VAVKRLKEERSPGGELQFQT---EVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMPNG----SVASRLR-ERL
.    ..|.|.||.|||..  . .  ||||..| ..   ...|  .   |...  .  | | .||.........  .| .|...|    . ..... .| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR-

PGDTPL--DWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEA----VVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLS-TGKSSEK
  ....  .. . |....  .||| |.|..   .|||||.| .|||.|....      ..||||||..||   . .| . ||.. .||| .    . . |
--HGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

TDVFGFGIMLLELITGQ
 |....|..| |...|.
VDMWSCGCILYEMLCGR

Kinase LRR2_a-1.AA TK 278-476 17 1.2e-42 140.29 In-house 1-389 (486) Show / Hide
Range on Protein: 278-476
Range on HMM: 1-389/486
Sequence Identity: 17% (70 aa)

FNNRNILGRGGFG---KVYKGRLADGS--------------------------LVAVKRLKEERSPGGELQFQ-------------TEVEMISMAV----
    . ||.| ||   .||||.. ...                           |||| |||. .   | .|.              |.|...|      
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLLRLRGFCMTPTE------------RLLVYPYMPNGS----VASRLRERLPGDTP-----------------------------------------
 | |..|| | |. . .             ..|  |||.|.      . ||.. |. ..                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWPTRKCIALGAARGLSYLHDH----CDPKIIHRDVKAANILLDEEYE-----------AVVGDFG--
                               |. ...  ... .|.|..|||..      ....|||. | |.|..|..            . ..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LAKLMDYKDTHVTTAVRGTI-------------------GH------IAPEYLS---------TGKSSEKTDVFGFGIMLLELIT
      ||. ....|  ...  .||                    |        ||| |          .|| ..|.||. ||... |. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT

Kinase LRR2_a-1.AA Pkinase_Tyr 278-476 29 4.5e-38 129.57 Pfam 1-209 (270) Show / Hide
Range on Protein: 278-476
Range on HMM: 1-209/270
Sequence Identity: 29% (65 aa)

FNNRNILGRGGFGKVYKGRLA-----DGSLVAVKRLKEERSPGG--ELQFQTEVEMISMA-VHRNLLRLRGFCMTPTER---LLVYPYMPNGSVASRLRE
      ||.| ||.||||..      ..  |||| |||  ..       |  |... .    | |..|| | |.   |    ..| .|||.|.  . ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

-RLPGDTPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAKLMDYKDTH-VTTA-----VRGTIGHIAPEYLSTGKSS
 | ... ||. ..  ....  |.|..||...    .||||. | |.|..|.  . ..|||||...  .|.  ...      .. .    ||| ...|| .
HR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFT

EKTDVFGFGIMLLELIT
.|.||  ||. . |..|
TKSDVWSFGVLMWEIFT

Kinase LRR2_a-1.AA S_TKc 278-552 22 2.3e-37 131.35 SMART 1-231 (231) Show / Hide
Range on Protein: 278-552
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

FNNRNILGRGGFGKVYKGRLAD-GSLVAVKRLKEERSPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMPN--GSVASRLRERLPGDTP-
.   ...|.|.||||||.|  . | .||.|..|         ... |... ..  | |. .| ... . ..  .|  |...  |.. .....| .. .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGFGIMLL
 ..  . ....   ...| |.|.|    |||||.| .||||||  .  ..|||||...        | . ||   .||| |  | . .| |.  .|..| 
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

ELITGQRAFDLARLANDDDVMLLDWVKGLLRERKVDLLVDPDLKNEYDPMEVEQLIQVALLCTQGSPMDRPKMAEVVR---------ML
|...|.  |.       .. |... ..                         .....    | |  | .||   |. .          .
EMLCGYPPFP-------QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LRR2_a-1.AA Dicty4 278-478 35 2.9e-37 121.93 In-house 1-214 (277) Show / Hide
Range on Protein: 278-478
Range on HMM: 1-214/277
Sequence Identity: 35% (77 aa)

FNNRNILGRGGFGKVYKGRLADGSLVAVKRL--KEERSPGGELQ-FQTEVEMISMAVHRNLLRLRGFCM----TPTERLLVYPYMPNGSVASRLRE---R
 |  ...|.|.||.||||.   |. |||| |  . . .   .|. |  ||.  .   | |.. . | |     .| . . |  ||| |...| |.     
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

LPGDTPLDWPTRKC---IALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAKLMDYKDTHVT--TAVRGTIGHIAPEYLSTGKSSEKT
    ..||||..|    .|. ||||. .||  |.| ||||| |..|.| |. . . |.||||...|    .| .  ... || .  ||| .      || 
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVFGFGIMLLELITGQ
||. |||.| |. |.|
DVYSFGIVLWEILTRQ

Kinase LRR2_a-1.AA MLK 278-478 27 7.3e-36 121.93 In-house 1-233 (291) Show / Hide
Range on Protein: 278-478
Range on HMM: 1-233/291
Sequence Identity: 27% (65 aa)

FNNRNILGRGGFGKVYKGRLADGSL-----VAVKRLK--EERSPGGE----LQFQTEVEMISMAVHRN----LLRLRGFCMTPTE-RLLVYPYMPNGSVA
...  ..| |.||||.|||   . .     ||||| .   . . . .     .|..|..  ..  |.|      ...| |  |.   ..|  |...|| .
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

SRLRERLP----------GDTPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDE------EYEAVVGDFGLAKLMDYKDTHVTTAVRGTI
. |... .           |   |      .||  |||..||| .  ..||||| |  |||.||      .  ... |||... .  ..    .  .|| 
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTY

GHIAPEYL---STGKSSEKTDVFGFGIMLLELITGQ
   ||| .     .| ||| ||. .|..| |..|..
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE

Kinase LRR2_a-1.AA TyrKc 278-552 25 4.4e-35 123.78 SMART 1-280 (280) Show / Hide
Range on Protein: 278-552
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

FNNRNILGRGGFGKVYKGRLADGSLVAVKRLKEERSPGGELQFQTEVEMISMA--VHRNLLRLRGFCMTP-------TERLLVYPYMPNGSVASRLRERL
     .||.| ||.||||..     |||| |||.     .  |  | .. ..    | |..|| | |...          ..|  |||.|.  ..||.. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

PGDTPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAKLMDYK-------DTHVTT---AVR--GTIGHIAPEYLSTG
|    | ...   ... .|.| .|||..   ..||||  | |.|..|.. . ..||||..  . .       |. ...     .    |   ||| . .|
PK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KSSEKTDVFGFGIMLLELITGQRAFDLARLANDDDV---MLLDWVKGLLRERKVDLLVDPDLKNEYDPM----EVEQLIQVALLCTQGSPMDRPKMAEVV
| ..|.||. ||... |. |      .      ...   |  . |  ......     . |.     ||      . . |. . | .  | ||| ..|..
KFTTKSDVWSFGVCMWEIFT------YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

RML
. .
ECF

Kinase LRR2_a-1.AA STE 278-478 20 1.1e-33 116.35 In-house 1-265 (359) Show / Hide
Range on Protein: 278-478
Range on HMM: 1-265/359
Sequence Identity: 20% (55 aa)

FNNRNILGRGGFGKVYKGRLAD----------------GSLVAVKRLKEERS----------------PGGELQFQTEVEMISMAV--HRNLLRLRGFCM
. .  ..|.|.||.|||..  .                | ..|.|... |..                .  . |.. |... .     | |  .  | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TP-------TERLLVYPYMPNGSVASRLRERLPGDTPLD----------WPTRKCIALGAARG-LSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFG
         .|  ..  ||..||. . ....     ||.           .  ..|.    .| |.|||.|    |||||.|.|||||     .   |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LAKLMDYK--------------DTH-VTTAVRGTIGHIAPEYLST------GKSSEKTDVFGFGIMLLELITGQ
... .. .              ..   .. . ||  . ||| ..       .. ..| |.  .|....|..||.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK

Kinase LRR2_a-1.AA DRK 285-476 34 5.9e-32 105.53 In-house 8-197 (258) Show / Hide
Range on Protein: 285-476
Range on HMM: 8-197/258
Sequence Identity: 34% (67 aa)

GRGGFGKVYKGRLADGSLVAVKRLKEERSPGGEL--QFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMPNGSVASRLRERLPGDTPLDWPTRKCI
|||..| |. |    |. ||||.|.       ..   |. |.....   | |     | |  | . . .  ||| || .. | .       .||| .| .
GRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDE---SIEMDWPLMKQM

ALGAARGLSYLHDHCDPKIIHRDVKAANILLDEEYEAVVGDFGLAK-LMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGFGIMLLELIT
.. .|.|. |||  |.| ||||| |  | | || .   | ||||.      |.   .    || . .||| |      || ||. |.| | |..|
MFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT

Kinase LRR2_a-1.AA TKL-Unique 282-479 31 2.7e-31 107.66 In-house 3-226 (290) Show / Hide
Range on Protein: 282-479
Range on HMM: 3-226/290
Sequence Identity: 31% (72 aa)

NILGRGGFGKVYKGRLADGSLVAVKRLK-EERSPGGELQ-FQTEVEMISMAV-HRNLLRLRGFCM----TPTERLLVYPYMPNGSVASRLRERLPGD---
| .|.||.|.||||  . |. ||.|... .| |   ..| |  ||  ...   | |.... |.||    .| .. .|  |.| ||  . |   ..     
NKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

---TPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEE-----YEAVVGDFGLAKLMDYKDTHVTT--------AVRGTIGHIAPEYLST
   ..|..  |  .|. .|.|. ||| ||.|.||||| |  |.|.|..     . . . ||||.|. .  ..  ..         . |..  .||| |. 
NNNCKLNMQQRVKMAIDIAQGMYYLH-HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GKSSEKTDVFGFGIMLLELITGQR
   . ||| ||. |||.| |..|...
NFCQYSEKSDVYSFGIVLWEIATRKI

Kinase LRR2_a-1.AA LISK 364-480 32 1.1e-24 77.02 In-house 84-238 (296) Show / Hide
Range on Protein: 364-480
Range on HMM: 84-238/296
Sequence Identity: 32% (51 aa)

LRERLP-GDT---PLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILLDEE----YEAVVGDFGLAKLMDYKDTH-------------------
|...|   |    || || |  |||. |.|.||||. .   ||||| |. |.|..|     ....|.|||.|..|| ..                     
LHQYLKDMDKHKIPLPWPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMP

--------------VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGFGIMLLELITGQRA
               . .. ||    ||| |   . .|. ||| |||.|.|.||. .|
MKRKIPKKCMNQRKRRMTICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA

Kinase LRR2_a-1.AA LRRK 332-482 32 1.2e-24 84.12 In-house 116-284 (351) Show / Hide
Range on Protein: 332-482
Range on HMM: 116-284/351
Sequence Identity: 32% (56 aa)

HRNLLRLRGFCMTPTERLLVYPYMPNGSVASRLRERLPGD-----TPLDWPTRKCIALGAARGLSYLHDHCDPKIIHRDVKAANILL---D---------
| |.. | |||. |  . .|  |.|.|.  ..|...         . ..| ..  |||  |.|. |||.| .|.||||| |  ||||   .         
HPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH-NPPIIHRDLKSPNILLWSSPQNHSPNYPN

EEYEAVVGDFGLAKLMDYKDTH-VTTAVRGTIGHIAPEYLSTG---KSSEKTDVFGFGIMLLELITGQ-RAFD
... | ..|||.   | . ... |.  . |..|  ||| .  .     .||.|.. ||. | ||.|.| ..||
AHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD

Kinase LRR2_a-1.AA LISK 283-337 30 5.8e-09 25.05 In-house 1-60 (296) Show / Hide
Range on Protein: 283-337
Range on HMM: 1-60/296
Sequence Identity: 30% (18 aa)

ILGRGGFGKVYKGRLA-DGSLVAVKRLKEE----RSPGGELQFQTEVEMISMAVHRNLLR
..|.|.|||||||..  .|. .|.| ...       |  .  .. ||.|. .  |.| ..
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQ

Kinase LRR2_a-1.AA LRRK 278-309 18 3.6e-07 21.39 In-house 1-60 (351) Show / Hide
Range on Protein: 278-309
Range on HMM: 1-60/351
Sequence Identity: 18% (11 aa)

FNNRNILGRGGFG-KVYKGRLAD---------------------------GSLVAVKRLK
.   . .|||||| .||.... .                           .. ||.| ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWN

Kinase LRR2_a-1.AA TK 521-552 21 0.001034 7.47 In-house 455-486 (486) Show / Hide
Range on Protein: 521-552
Range on HMM: 455-486/486
Sequence Identity: 21% (7 aa)

PMEVEQLIQVALLCTQGSPMDRPKMAEVVRML
... | . .. . | .  | ||| .......|
HCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase LRR2_a-1.AA LRRK 533-554 31 0.025264 4.01 In-house 330-351 (351) Show / Hide
Range on Protein: 533-554
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

LCTQGSPMDRPKMAEVVRMLEG
.| |. | .||.. ..|  |. 
HCWQHDPKKRPHFSQIVKRLSQ

Kinase LRR2_a-1.AA DRK 534-554 38 0.068569 2.23 In-house 238-258 (258) Show / Hide
Range on Protein: 534-554
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CTQGSPMDRPKMAEVVRMLEG
|    |  || | |..  || 
CWNEDPQHRPSMQECLERLEA

Kinase LRR2_a-1.AA MLK 539-552 35 0.102987 1.88 In-house 278-291 (291) Show / Hide
Range on Protein: 539-552
Range on HMM: 278-291/291
Sequence Identity: 35% (5 aa)

PMDRPKMAEVVRML
| .||.....|  |
PHKRPSFRQIVQHL

Kinase LRR2_a-1.AA LISK 525-552 25 0.109822 1.02 In-house 269-296 (296) Show / Hide
Range on Protein: 525-552
Range on HMM: 269-296/296
Sequence Identity: 25% (7 aa)

EQLIQVALLCTQGSPMDRPKMAEVVRML
........ |.   | .||. .|.|. |
PPFLDLCFDCCKYDPKNRPSFKEIVQWL

Kinase LRR2_a-1.AA Pkinase_Tyr 532-552 33 3.455054 1.26 Pfam 250-270 (270) Show / Hide
Range on Protein: 532-552
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

LLCTQGSPMDRPKMAEVVRML
..| .  | ||| ..|....|
KQCWHYDPEDRPTFSEIHEQL