Gene LRR25_b-1 (S.moellendorffii)

LRR25_b-1

Species: S.moellendorffii
Alias: LRR25_b-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR25

Sequence

Name Sequence Type Origin Length Description Download
LRR25_b-1.AA Protein None 670 None Fasta, JSON
LRR25_b-1.NA RNA None 2013 None Fasta, JSON
LRR25_b-1.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of LRR25_b-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR25_b-1.AA LRRNT_2 1-32 31 0.000374 16.39 Pfam 11-46 (46) Show / Hide 
Range on Protein: 1-32
Range on HMM: 11-46/46
Sequence Identity: 31% (12 aa)

LYGSWNS-PR----LSGWNSGP-GGDPCGESWQGVLCT
.  |.|. ..    || ||.   ..|.|   | || |.
FKSSLNDSDPHHGVLSSWNPSSSDSDCCS--WTGVTCD
LRR_1 LRR25_b-1.AA LRR_1 128-150 48 0.00019 19.94 Pfam 1-26 (26) Show / Hide 
Range on Protein: 128-150
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

NLNLLDVSF-N--QLTGSLPSS-FAGL
||  ||.|  |  .|||..|.| | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_BAC LRR25_b-1.AA LRR_BAC 79-98 55 0.000229 21.75 SMART 1-20 (20) Show / Hide 
Range on Protein: 79-98
Range on HMM: 1-20/20
Sequence Identity: 55% (11 aa)

PPQLQEMYLSNNQLTGLPYS
||.|.... |||||| ||  
PPHLKWLNVSNNQLTELPEL
LRR_1 LRR25_b-1.AA LRR_1 104-126 37 0.000897 17.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 104-126
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLTKIDVSH-N--QLIGTIPDV-FQNF
.|...|.|. |  .| |.||.  | |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR25_b-1.AA LRR_1 81-102 37 0.002034 16.29 Pfam 1-26 (26) Show / Hide 
Range on Protein: 81-102
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLQEMYLSN-N--QLT-GLPYS-LKDL
.||. .||. |  .||  .| | .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR25_b-1.AA LRR_1 59-78 40 0.027674 12.27 Pfam 1-26 (26) Show / Hide 
Range on Protein: 59-78
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

NLKILDLSN-N--QLS-QAIPY---QL
||..||||. |  .|. . ||    .|
NLQHLDLSGCNCCNLTGH-IPPSCFNL
LRR_BAC LRR25_b-1.AA LRR_BAC 126-146 47 0.557785 3.16 SMART 1-20 (20) Show / Hide 
Range on Protein: 126-146
Range on HMM: 1-20/20
Sequence Identity: 47% (10 aa)

FSNLNLLDVSFNQLTGSLPSS
 ..|  |.||.|||| .||  
PPHLKWLNVSNNQLT-ELPEL
LRR_BAC LRR25_b-1.AA LRR_BAC 102-122 28 0.914587 1.52 SMART 1-20 (20) Show / Hide 
Range on Protein: 102-122
Range on HMM: 1-20/20
Sequence Identity: 28% (6 aa)

LWSLTKIDVSHNQLIGTIPDV
  .|....||.|| . . |. 
PPHLKWLNVSNNQ-LTELPEL
LRR_1 LRR25_b-1.AA LRR_1 152-173 18 2.711034 5.21 Pfam 1-26 (26) Show / Hide 
Range on Protein: 152-173
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

SISVMHVQN-N--KLSGDINV--LSDL
.. . .... |  .|.|.|    .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR25_b-1.AA LRR_1 174-196 22 18.163132 2.28 Pfam 1-26 (26) Show / Hide 
Range on Protein: 174-196
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

PLADLNVEN-N--QFNGWVPSS-LRSI
 |  |.. . |  .. | .|.| . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR25_b-1.AA IRAK 363-577 35 8.6e-62 211.6 In-house 1-233 (317) Show / Hide 
Range on Protein: 363-577
Range on HMM: 1-233/317
Sequence Identity: 35% (82 aa)

FAQENLLGEGSLGRVYRAELQNGT-PLAVKKL--DASGSTVQTNEEFLA---FVSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNRGTLHEMLHVLD-E
|...|..|||  | |||....| | . |||||   |. |. .  ..|..    . . .|.|| |. .| |||.| ..  |||.|   |.|.  |. .|  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

TS-KRLSWNQRVKIALGAARALEYLHEVCSP-AVVHRNFKSANILLDDDMSPHLTDCGLAALS---STSSDRQV----AAQMLGSFGYSAPEFAM--SGV
.. | ||| ||..|..|.|.....||.. .  .. |.. ||||||||... | ..| ||.  .   | . .  .    .    |.  | .|||    .| 
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

YTVKSDVYSFGVVMLELLTGRKPLDSSRARSEQ
.|.|.||||||.| ||.|||... .. |.. ..
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYY
Kinase LRR25_b-1.AA TKL 369-638 19 1.1e-58 201.26 In-house 1-364 (364) Show / Hide 
Range on Protein: 369-638
Range on HMM: 1-364/364
Sequence Identity: 19% (76 aa)

LGEGSLGRVYRAELQN---------GTPLAVKKLDASGSTVQTN-------------------------EEFLAFVSTIARLRHTNVTELVGYCAEHGQ-
.|.|. | ||......         |.. ||||.    .   |                          ...   .  . |||| |.  ..||| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEYFNRGT-LHEMLHVLDETSKRLSWNQRVKIALGAARALEYLHEVCS-----PAVVHRNFKSANILLDDDMS-----------
              .|.||  .|. || ..           |.||...||..||...|||         |...||. ||.|||.|...            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---PHLTDCGLAALSSTS-----------------SDRQVAAQMLGSFGYSAPEFAM----------------SGVYTVKSDVYSFGVVMLELLTGRKPL
   . ..| ||.   |.|                 . |.      |.... |||  .                .. |. |.||||||.|. |.||...  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

DSSRARSEQSLVRWATPQLHDIDAL---------SKMVDPALKGIYP------------AKSLSRFADVISSCVQPEPEFRPPMSEVVQSL
                 ... .. .         .. .|  |.   |               . .... .  | ...|| || ..|... |
--------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR25_b-1.AA TKL-Unique 367-564 30 1.9e-45 157.28 In-house 3-224 (290) Show / Hide 
Range on Protein: 367-564
Range on HMM: 3-224/290
Sequence Identity: 30% (68 aa)

NLLGEGSLGRVYRAELQNGTPLAVKKLDA-SGSTVQTNEEFLAFVSTIARLR-HTNVTELVGYCA----EHGQRLLVYEYFNRGTLHEMLH---VLD---
|..|||. |.||...  .|.| |.|..   ..|  .  .||   |... .|. | |.. ..|||.      ... .| ||...|.|.. ||    .    
NKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

ETSKRLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDD-----MSPHLTDCGLAALSSTSSDRQVA-------AQMLGSFGYSAPEFAMS
. .. |...||||.|. .|....|||    | . ||. || |.|.| .     ..  . | ||. ..|....  .        .  .||| ..|||  ..
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GVYTVKSDVYSFGVVMLELLTG
    |. ||||||||.|. |..|.
NFCQYSEKSDVYSFGIVLWEIATR
Kinase LRR25_b-1.AA MLK 363-638 21 1.6e-34 117.22 In-house 1-291 (291) Show / Hide 
Range on Protein: 363-638
Range on HMM: 1-291/291
Sequence Identity: 21% (67 aa)

FAQENLLGEGSLGRVYRAELQNGT----PLAVKKLD--ASGSTVQT---NEEFLAFVSTIARLRHTN----VTELVGYCAEHGQ-RLLVYEYFNRGTLHE
.  .  .|.|| | |.... .| .     .|||. .  .  . ..|    ..|  ..   ..|.| |    . ...| |.....  ..| ||   | |..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

MLHVLDETSK----------RLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDD------DMSPHLTDCGLAALSSTSSDRQVAAQMLGSF
 ||  .  .           . .  . ...||  ||...|||.   ....||  || |||.|.      ..    .| |..   ...   .    . |..
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTY

GYSAPEF---AMSGVYTVKSDVYSFGVVMLELLTGRKPLDSSRARSEQSLVRWATPQLHDIDALSKMVDPALKGIY---PAKSLSRFADVISSCVQPEPE
 . |||    . .. |. |.||.|.|||. |.||.. | .                   ..|..      |..|.    |     ...  .. | ...|.
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYK------------------QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPH

FRPPMSEVVQSL
 || ....|| |
KRPSFRQIVQHL
Kinase LRR25_b-1.AA LRRK 363-569 24 7.3e-33 113.58 In-house 1-284 (351) Show / Hide 
Range on Protein: 363-569
Range on HMM: 1-284/351
Sequence Identity: 24% (72 aa)

FAQENLLGEGSLG-RVYRAELQN---------------------------GTPLAVKKLDASGSTVQTN-----------------------------EE
.  |...|.|. | .||||....                           ... |.||..  . |. .                              . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FLAF---VSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNRGTLHEMLHVLDETS----K-RLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANI
|  |   |. . .|.| |.  |.|.| ..  . .| ||   |.|.. ||   ...    | ..||. . ||||  |...||||  ..| ..||. || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNI

LL---D---------DDMSPHLTDCGLAALSSTSSDRQ-VAAQMLGSFGYSAPEFAMSG---VYTVKSDVYSFGVVMLELLTGR-KPLD
||   .         ...  .. | |.      ....  ||  ..| .|. |||    .   .|| |.|.||||... ||||..  | |
LLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase LRR25_b-1.AA Pkinase 363-581 21 8.3e-33 117.09 Pfam 1-228 (293) Show / Hide 
Range on Protein: 363-581
Range on HMM: 1-228/293
Sequence Identity: 21% (51 aa)

FAQENLLGEGSLGRVYRAELQNG-TPLAVKKLDASGSTVQTNEEFLA--FVSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNRG----TLHEMLHVLDE
.  .  .|.|| |.||..  ..     |||... ..   . ... .    ..  .||.| |. .| ... ...   .| || . |     |......  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

TSKRL--SWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSP----HLTDCGLAALSSTSSDRQVAAQMLGSFGYSAPEFAM-SGVYTVK
 ....  |...  ....  .|.|||.|.     ..||  |..|||.|... .    ...| |||.. .     . .    |. .| |||  . .  |. |
RHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

SDVYSFGVVMLELLTGRKPLDSS----RARSEQSLVR
.|..|.|... |.|.|| | ...    . .... ...
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMIC
Kinase LRR25_b-1.AA TK 363-567 16 1.3e-31 102.62 In-house 1-394 (486) Show / Hide 
Range on Protein: 363-567
Range on HMM: 1-394/486
Sequence Identity: 16% (64 aa)

FAQENLLGEGSLG---RVYRAELQNG--------------------------TPLAVKKLDA-SGSTVQTNEE-----------FLAFVSTIARLR----
   .. ||||  |   .||..|....                          || ||| | . .... .  ..           ||.... .. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HTNVTELVGYCAEH------------GQRLLVYEYFNRGT----LHEMLHVLDETSKR-----------------------------------------
 | |.  |.|.| ..            .  ..| || . |     |.. |.  ... .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSWNQRVKIALGAARALEYLHEV-CSPA---VVHRNFKSANILLDDDMS-----------PHLTDCGLA
                               |.  |.. ... .|...||||.  |.     .|||.    |.|.....              ..| ||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

-------ALSSTSSDRQVAAQ----MLGSFG----------------------YSAPEFAMSGV---------YTVKSDVYSFGVVMLELLT-GRKP
       |    |.|  ....    ...                         . |||  ...|         .| ||||.||||.| |..| |..|
RQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase LRR25_b-1.AA Dicty4 363-567 31 1.4e-28 92.61 In-house 1-216 (277) Show / Hide 
Range on Protein: 363-567
Range on HMM: 1-216/277
Sequence Identity: 31% (69 aa)

FAQENLLGEGSLGRVYRAELQNGTPLAVKKL--DASGSTVQTNEEFLAFVSTIARLRHTNVTELVGYCA----EHGQRLLVYEYFNRGTLHEMLHV---L
 . |...|.||.| ||..    |.  |||||  .  ..   . .||.. |.  . .|| |.  . |.|     . |  . | ||  .|.|.. ||     
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

DETSKRLSWNQRVK---IALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLAALSSTSSDRQV-AAQMLGSFGYSAPEFAMSGVYTVKS
   |. |.|  . .   .|. ||| . .||. | | ..||  ||.|.| |...    .| ||...  . .| .  .  . |. .. |||  |.  |. |.
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGVVMLELLTGRKP
|||||| |  |.||.  |
DVYSFGIVLWEILTRQEP
Kinase LRR25_b-1.AA RAF 363-567 26 7.5e-28 87.14 In-house 1-220 (282) Show / Hide 
Range on Protein: 363-567
Range on HMM: 1-220/282
Sequence Identity: 26% (61 aa)

FAQENLLGEGSLGRVYRAELQNGTPLAVKKLDASGSTVQTNEE---FLAFVSTIARLRHTNVTELVGYCAEHG--QRLLVYEYFNRGTLHEMLHVLDETS
.   .  |.|| | |||..     . |||.|  .  | .       |   |.   . || |.    ||  .        | ...   .|   .||  || 
VMVMTRIGSGSFGTVYRGHWH--GDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIHVQ-ETR

KRLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLAALSSTSS--DRQVAAQMLGSFGYSAPEFAM--------------
...  .. . |..  . ...|||      ..||  || ||.|..||.   .| ||. . .  |    | . |  ..  . ||| .               
EKFDMHWLIDISRQVCQGMDYLHAK---NIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQD

SGVYTVKSDVYSFGVVMLELLTGRKP
   |. .|||||||.|| ||.|.. |
ENPYSFQSDVYSFGIVMYELMTRHMP
Kinase LRR25_b-1.AA S_TKc 363-645 20 7.7e-27 96.41 SMART 1-231 (231) Show / Hide 
Range on Protein: 363-645
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

FAQENLLGEGSLGRVYRAELQN-GTPLAVKKLDASGSTVQTNEEFLAFVSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNR--GTLHEMLHVLDETSKR
.   ...|.|. |.||..   . |   |.|...         | ..  ..   . .| |.  | ... . .   .| || .   |.|.....      .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLAALSSTSSDRQVAAQMLGSFGYSAPEFAMSGVYTV-KSDVYSFGV
  ..  .  ...   ..||||.|.     ..||  | .|||||.     ..| |||..            . |.  | |||      |.  |.|..|.|.
FPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

VMLELLTGRKPLDSSRARSEQSLVRWATPQLHDIDALSKMVDPALKGIYPAKSLSRFADVISSCVQPEPEFRPPMSEVVQ--SLVRLMQRA
.. |.|.|. | .      .| . .                             . . | |. | | .|| ||   |. |  .......  
ILYEMLCGYPPFP-----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR25_b-1.AA TKL-ciliate2 363-561 27 6.6e-25 79.59 In-house 1-211 (273) Show / Hide 
Range on Protein: 363-561
Range on HMM: 1-211/273
Sequence Identity: 27% (60 aa)

FAQENLLGEGSLGRVYRAELQNGTPLAVKKLDASGSTVQTNEEFLAFVSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNRGTLHEMLHVLDETSKRLSW
   .| . ||  | .|.|     .  ||||        |.  .|.     .  ||| |.   .| | .     .. ||  || |  .|    . . ||.|
LEIQNKITEGGYGIIYKAKWREIV-VAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQ---NQDVRLTW

NQRVKIALGAARALEYLHEVCSPAVVHRNFK--------------------SANILLDDDMSPHLTDCGLAALSSTSSDRQVAAQMLGSFGYSAPEFAMS
  | .||| .||   |||    | ..||  |                    | |.|.|| .   ||| |         .       .| . . |||   .
EDRRRIALDIARGVHYLH-SSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVK---PQDNYMTNKIGTYQWMAPEVIKA

GVYTVKSDVYSFGVVMLEL
 .|| | ||.|..... |.
FYYTEKADVFSYSIILWEI
Kinase LRR25_b-1.AA STE 363-633 18 3.3e-24 82.43 In-house 1-350 (359) Show / Hide 
Range on Protein: 363-633
Range on HMM: 1-350/359
Sequence Identity: 18% (69 aa)

FAQENLLGEGSLGRVYRAELQN----------------GTPLAVKKLDASGSTV---------------QTNEEFLAFVSTIARLR--HTNVTELVGYCA
.     .|.|. | ||.|   .                |.  |.|... . ..                .  ...|  ...  ...  | |. .  |.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EHG-------QRLLVYEYFNRGTLHEMLHVLDETSKRLS----------WNQRVKIALGAARA-LEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCG
  |       .  .. || . |.| ....   .. |.|.           .|  .|.    .. |.|||.     ..||  |.|||||       |.| |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LAALSSTS--------------SDRQVAAQMLGSFGYSAPEFAMS------GVYTVKSDVYSFGVVMLELLTGRKPL---DSSRARSEQSLVR-------
...  . |              .  |    . |.  . |||  .       . |..|.|..|.| ...|..||. |.      ||  .            
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

------WATPQLHD-------------IDALSKMVDPALKGIYPAKSLSRFADVISSCVQPEPEFRPPMSE
         |.| |                .           || |  . | | |. | | .|. ||  |.
QLCIVNGPPPPLPDHLSQNEMISYGGSGT-T-----------YPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase LRR25_b-1.AA Pkinase_Tyr 363-503 24 2.4e-18 62.73 Pfam 1-148 (270) Show / Hide 
Range on Protein: 363-503
Range on HMM: 1-148/270
Sequence Identity: 24% (37 aa)

FAQENLLGEGSLGRVYRAELQ-----NGTPLAVKKLDASGSTVQT--NEEFLAFVSTIARL-RHTNVTELVGYCA-EHGQ--RLLVYEYFNRGTLHEMLH
      ||||. |.||....      ...| |||.|   |.. .    |.|.. ...   | .| |.  |.| |  . ..   ..| ||   | |.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

VLDETSKRLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDM
   |  ..|.  . .....  |...|||..      .||     |.|.....
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENN
Kinase LRR25_b-1.AA TyrKc 363-638 20 3.3e-17 55.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 363-638
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

FAQENLLGEGSLGRVYRAELQNGTPLAVKKLDASGSTVQTNEEFLAFVSTIARL--RHTNVTELVGYCAEH-------GQRLLVYEYFNRGTLHEMLHVL
   .  ||||  |.||....   .. |||.| ..       |.|.   .   .|  .| |.  |.|.| ..       .. ..| ||   | |.. |.  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

DETSKRLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLAALSSTS------SDRQVA-----AQMLGSFGYSAPEFAMS
 ..   |.. . ..... .|.  ||||.     ..||     |.|....     .| ||.            .|  ..     . ..      |||  . 
RPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

GVYTVKSDVYSFGVVMLELLTGRKPLDSSRARSEQSLVRWATPQLHDIDALSKMVDPALKGIYPA--------KSLSRFADVISSCVQPEPEFRPPMSEV
|..| ||||.||||.| |..|  ..  .  .             . ..... .  .     . |          .   .  ....| . .|| || .||.
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ----------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI

VQSL
.. .
HECF
Kinase LRR25_b-1.AA Pkinase_Tyr 536-567 54 6e-09 30.94 Pfam 182-214 (270) Show / Hide 
Range on Protein: 536-567
Range on HMM: 182-214/270
Sequence Identity: 54% (18 aa)

APEFAMSGVYTVKSDVYSFGVVMLELLT-GRKP
|||  . |..|.||||.||||.| |..| |..|
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase LRR25_b-1.AA TK 613-638 30 4.4e-05 12.15 In-house 461-486 (486) Show / Hide 
Range on Protein: 613-638
Range on HMM: 461-486/486
Sequence Identity: 30% (8 aa)

FADVISSCVQPEPEFRPPMSEVVQSL
..|.. .| ...|| || .|.... |
YYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR25_b-1.AA Pkinase_Tyr 615-638 37 0.003933 11.23 Pfam 247-270 (270) Show / Hide 
Range on Protein: 615-638
Range on HMM: 247-270/270
Sequence Identity: 37% (9 aa)

DVISSCVQPEPEFRPPMSEVVQSL
|.. .| ...|| || .||... |
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase LRR25_b-1.AA LRRK 612-640 34 0.013384 5.0 In-house 323-351 (351) Show / Hide 
Range on Protein: 612-640
Range on HMM: 323-351/351
Sequence Identity: 34% (10 aa)

RFADVISSCVQPEPEFRPPMSEVVQSLVR
.. | | .| | .|. || .|..|. |  
MYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR25_b-1.AA TKL-ciliate2 595-639 24 0.026819 2.81 In-house 229-273 (273) Show / Hide 
Range on Protein: 595-639
Range on HMM: 229-273/273
Sequence Identity: 24% (11 aa)

KMVDPALKGIYPAKSLSRFADVISSCVQPEPEFRPPMSEVVQSLV
|..   |.   |     .|||..  | . . ..|| . |... | 
KVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase LRR25_b-1.AA IRAK 628-638 45 0.203581 0.99 In-house 307-317 (317) Show / Hide 
Range on Protein: 628-638
Range on HMM: 307-317/317
Sequence Identity: 45% (5 aa)

RPPMSEVVQSL
|..| .|.|.|
RCDMAWVMQQL
Kinase LRR25_b-1.AA Dicty4 606-640 24 0.217805 0.59 In-house 241-277 (277) Show / Hide 
Range on Protein: 606-640
Range on HMM: 241-277/277
Sequence Identity: 24% (9 aa)

PAKSLSRFADVISSCVQPEPEFRPPMSEVVQS--LVR
|.  . .... |  |  ..|. || ..|..|   |  
PDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase LRR25_b-1.AA TKL-Unique 612-638 29 0.333066 0.22 In-house 264-290 (290) Show / Hide 
Range on Protein: 612-638
Range on HMM: 264-290/290
Sequence Identity: 29% (8 aa)

RFADVISSCVQPEPEFRPPMSEVVQSL
.. | |  |  ..|. ||  .|.. .|
EYRDLIQQCWHHDPSQRPSFDEIIHRL