Gene LRR36_m (S.moellendorffii)

LRR36_m

Species: S.moellendorffii
Alias: LRR36_m
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR36

Sequence

Name Sequence Type Origin Length Description Download
LRR36_m.AA Protein None 85 None Fasta, JSON
LRR36_m.NA RNA None 258 None Fasta, JSON
LRR36_m.kin_dom Protein Kinase Domain None 70 None Fasta, JSON

Protein domain

Protein domains of LRR36_m.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LRR36_m.AA IRAK 2-71 28 1.4e-11 37.49 In-house 1-77 (317) Show / Hide 
Range on Protein: 2-71
Range on HMM: 1-77/317
Sequence Identity: 28% (22 aa)

FSSHHLIGVGGDSKVYKGQLHTGSEVVAIK----RAQKEYLQGVEEFRP---EIELFSRLHHKNLVNLIGFCTDDGE
|.  ..|| ||   ||.||..    ..|.|     |  .  .  ..|.    |... .|..|.|.| | |.||. ..
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQC
Kinase LRR36_m.AA TKL 8-70 21 2.6e-10 33.36 In-house 1-98 (364) Show / Hide 
Range on Protein: 8-70
Range on HMM: 1-98/364
Sequence Identity: 21% (21 aa)

IGVGGDSKVYKGQLHTGS--------EVVAIKRAQKEYLQGV---------------------------EEFRPEIELFSRLHHKNLVNLIGFCTDDG
|| || ..||||...  .        ..||.|.  ... .                             .... || . |||.| |.| ..|.|.. .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPP
Kinase LRR36_m.AA Pkinase_Tyr 15-74 33 3.1e-10 35.31 Pfam 14-83 (270) Show / Hide 
Range on Protein: 15-74
Range on HMM: 14-83/270
Sequence Identity: 33% (24 aa)

KVYKGQLH----TGSEVVAIKRAQKEYLQGV----EEFRPEIELFSRL-HHKNLVNLIGFCTDDGEQ--ML
.|||| ..     .   ||.|   ||.        |.|  |... . | ||.|.|.|.| |||.||.  ..
EVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIY
Kinase LRR36_m.AA TK-Unique 2-76 22 6.4e-10 30.52 In-house 1-84 (294) Show / Hide 
Range on Protein: 2-76
Range on HMM: 1-84/294
Sequence Identity: 22% (19 aa)

FSSHHLIGVGGDSKVYKGQLHTGS------EVVAIKRAQ-KEYLQGVEEFRPEIELFSRLH-HKNLVNLIGFCTDDG-EQMLAY
.    .|| |  . |..|.. ...       .||.|  . .. .. . .|  ||.... |  |.|.|...| ||...  .|...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIM
Kinase LRR36_m.AA Abl 2-67 31 2.1e-09 27.02 In-house 1-65 (252) Show / Hide 
Range on Protein: 2-67
Range on HMM: 1-65/252
Sequence Identity: 31% (21 aa)

FSSHHLIGVGGDSKVYKGQLHTGSEVVAIKRAQKEYLQGVEEFRPEIELFSRLHHKNLVNLIGFCT
 . .| .| |    ||.|     . .||.|  . . .. |.||  |  .   ..|.||| |.| ||
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTME-VHEFLKEAAIMKEMKHPNLVQLLGVCT
Kinase LRR36_m.AA TKL-Unique 4-68 33 2.5e-09 29.25 In-house 1-67 (290) Show / Hide 
Range on Protein: 4-68
Range on HMM: 1-67/290
Sequence Identity: 33% (23 aa)

SHHLIGVGGDSKVYKGQLHTGSEVVAIKRAQK---EYLQGVEEFRPEIELFSRLH-HKNLVNLIGFCTD
   .|| || ..||||  ..  . ||||.  .     .. ..||. |. . ..|| |.|.| ..|.|.|
FWNKIGEGGYGQVYKGKWRG--YPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMD
Kinase LRR36_m.AA Pkinase 2-71 27 2.8e-09 33.91 Pfam 1-74 (293) Show / Hide 
Range on Protein: 2-71
Range on HMM: 1-74/293
Sequence Identity: 27% (20 aa)

FSSHHLIGVGGDSKVYKGQLHTGSEVVAIKRAQKEYLQGVEE--FRP--EIELFSRLHHKNLVNLIGFCTDDGE
.  .  || |. ..|||.. .  ...||.|.  |.     ..   |   ||..  ||.|.| | |.....|...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDH
Kinase LRR36_m.AA ULK 2-69 24 5.8e-09 27.51 In-house 1-90 (329) Show / Hide 
Range on Protein: 2-69
Range on HMM: 1-90/329
Sequence Identity: 24% (22 aa)

FSSHHLIGVGGDSKVYKGQ-LHTG---SEVVAIKRAQKEYLQGVEE----------FRPEIELFSRLH----HKN----LVNLIGFCTDD
.. .| .| |   |||||    |.    |.||.|  .|....  .           .. ||..  .|.    |||     | |. .. ..
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETS
Kinase LRR36_m.AA MLK 2-70 22 8.2e-09 26.83 In-house 1-82 (291) Show / Hide 
Range on Protein: 2-70
Range on HMM: 1-82/291
Sequence Identity: 22% (19 aa)

FSSHHLIGVGGDSKVYKGQLHTGS---EVVAIKRAQ--KEYLQGV-----EEFRPEIELFSRLHHKN----LVNLIGFCTDDG
.  |. ||.|.  ||.||. .       .||.||.   ..   ..     ..|. |......| |.|     . . | |....
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP
Kinase LRR36_m.AA ULK 2-69 22 1.1e-08 26.99 In-house 1-87 (324) Show / Hide 
Range on Protein: 2-69
Range on HMM: 1-87/324
Sequence Identity: 22% (20 aa)

FSSHHLIGVGGDS-KVYKGQ-LHTG--SEVVAIKRAQKEYLQGVEEFRP----------EIELFSRLH---HKN--LVNLIGFCTDD
.. .| .| |    |||||    |.   ..||.|  .| ...  .  ..          ||..   |.   |.|   | |. .. ..
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETS
Kinase LRR36_m.AA Ror 15-69 40 2.1e-07 25.86 In-house 14-74 (308) Show / Hide 
Range on Protein: 15-69
Range on HMM: 14-74/308
Sequence Identity: 40% (25 aa)

KVYKGQLHTGS-----EVVAIKRAQKE-YLQGVEEFRPEIELFSRLHHKNLVNLIGFCTDD
|||||.|  .        ||||   ..   .  ..|| ||.| ..||| | | |.| || |
KVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMD
Kinase LRR36_m.AA LRRK 2-68 17 2.6e-07 21.9 In-house 1-128 (351) Show / Hide 
Range on Protein: 2-68
Range on HMM: 1-128/351
Sequence Identity: 17% (23 aa)

FSSHHLIGVGGDS-KVYKGQLH--------------------------TGSEVVAIKRAQKE----------------------------------YLQG
. .  .||.||   .||.. .                             .. ||||   ..                                   .  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

VEEFRPEIELFSRLHHKNLVNLIGFCTD
  ||| |. . |.|.| |.|.|.||| .
FREFRHEVWIMSHLNHPNIVSLKGFCIH