Gene LRR36_k (S.moellendorffii)

LRR36_k

Species: S.moellendorffii
Alias: LRR36_k
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR36

Sequence

Name Sequence Type Origin Length Description Download
LRR36_k.AA Protein None 175 None Fasta, JSON
LRR36_k.NA RNA None 528 None Fasta, JSON
LRR36_k.kin_dom Protein Kinase Domain None 140 None Fasta, JSON

Protein domain

Protein domains of LRR36_k.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LRR36_k.AA TKL 86-138 38 9.8e-19 64.1 In-house 131-202 (364) Show / Hide 
Range on Protein: 86-138
Range on HMM: 131-202/364
Sequence Identity: 38% (28 aa)

FATRLRIALGSARGILYLHTEAN-----PPIFHRDIKASNILLDGKNI--------------PKVADFGLSR
.  |.|.||. |||. |||..       ||| |||.| .|||.| ..               .|..||||||
WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSR
Kinase LRR36_k.AA HH498 87-138 40 2.2e-16 48.1 In-house 121-172 (284) Show / Hide 
Range on Protein: 87-138
Range on HMM: 121-172/284
Sequence Identity: 40% (21 aa)

ATRLRIALGSARGILYLHTEANPPIFHRDIKASNILLDGKNIPKVADFGLSR
. ...|..  |.|  |||  . .|| |||    |||..   . .||||| ||
QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESR
Kinase LRR36_k.AA IRAK 88-138 50 4.1e-16 53.73 In-house 110-161 (317) Show / Hide 
Range on Protein: 88-138
Range on HMM: 110-161/317
Sequence Identity: 50% (26 aa)

TRLRIALGSARGILYLHTEA-NPPIFHRDIKASNILLDGKNIPKVADFGLSR
.|. |..|.|.|| .||.     || |.||| .|||||    || .|||| |
QRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHR
Kinase LRR36_k.AA IRAK 22-84 29 1.2e-15 52.01 In-house 1-71 (317) Show / Hide 
Range on Protein: 22-84
Range on HMM: 1-71/317
Sequence Identity: 29% (21 aa)

FDDARLVGQGGYGKVYRGVLSDGH-VVAVK--RAEEGSLQGTHE--FYT---EIELLSRVHHRNLLSLVGY
|. ... |.||.| ||||...    ..|||  .... . .. |.  | .   |.....| .| |...| ||
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGY
Kinase LRR36_k.AA Dicty4 86-138 42 2.7e-15 47.63 In-house 108-162 (277) Show / Hide 
Range on Protein: 86-138
Range on HMM: 108-162/277
Sequence Identity: 42% (24 aa)

FATRLR---IALGSARGILYLHTEANPPIFHRDIKASNILLDGKNIPKVADFGLSR
. ...|   .|.  |||. .||.  || | |||.|..|.| |  .  ||.|||||.
WPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQ
Kinase LRR36_k.AA Dicty4-Unclassified 90-138 46 2.8e-15 48.75 In-house 112-157 (263) Show / Hide 
Range on Protein: 90-138
Range on HMM: 112-157/263
Sequence Identity: 46% (23 aa)

LRIALGSARGILYLHTEANPPIFHRDIKASNILLDGKNIPKVADFGLSR
...|.  |.|. .|||     . |||||.||||.|  .  |.||||.||
IKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISR
Kinase LRR36_k.AA MLK 91-138 46 4.5e-14 45.33 In-house 128-181 (291) Show / Hide 
Range on Protein: 91-138
Range on HMM: 128-181/291
Sequence Identity: 46% (25 aa)

RIALGSARGILYLHTEANPPIFHRDIKASNILLD------GKNIPKVADFGLSR
..||  |||. ||| .| .|| |||.| .|||.|      .. . |..|||.||
NWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR
Kinase LRR36_k.AA Pkinase 97-161 31 1.3e-12 45.64 Pfam 118-175 (293) Show / Hide 
Range on Protein: 97-161
Range on HMM: 118-175/293
Sequence Identity: 31% (22 aa)

ARGILYLHTEANPPIFHRDIKASNILLDGKNIP----KVADFGLSRLAPSPDLDGVTPGHVSTVVKGTP
.||. |.| .    | |||.| .|||.| .. .    |..||||....         ...  |.. |||
LRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTP
Kinase LRR36_k.AA TKL-Unique 86-140 40 2.4e-12 40.0 In-house 109-167 (290) Show / Hide 
Range on Protein: 86-140
Range on HMM: 109-167/290
Sequence Identity: 40% (25 aa)

FATRLRIALGSARGILYLHTEANPPIFHRDIKASNILLDGK------NIPKVADFGLSRLA
.. |...|.  |.|  |||..  | | |||.| ||.|.| .      || |..|||||...
MQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNI-KICDFGLSKFN
Kinase LRR36_k.AA TKL 28-84 21 2.3e-11 37.18 In-house 1-93 (364) Show / Hide 
Range on Protein: 28-84
Range on HMM: 1-93/364
Sequence Identity: 21% (20 aa)

VGQGGYGKVYRGVLSD---------GHVVAVKRAEEGSLQGT---------------------------HEFYTEIELLSRVHHRNLLSLVGY
.|.||.|.||.|..           | .||||.  . . . .                            ..  || ..|| .| |.....||
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGY
Kinase LRR36_k.AA LRRK 88-155 40 2.3e-11 36.43 In-house 165-242 (351) Show / Hide 
Range on Protein: 88-155
Range on HMM: 165-242/351
Sequence Identity: 40% (32 aa)

TRLRIALGSARGILYLHTEANPPIFHRDIKASNILLDGKNIP------------KVADFGLSRLAPSPDLDGVTPGHVST
..|.|||  |.|. |||  .|||| ||| |  |||| . . .            |.||||.||.  .... ||..| | .
LKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGN
Kinase LRR36_k.AA CMGC 98-138 29 3.9e-11 31.88 In-house 191-252 (513) Show / Hide 
Range on Protein: 98-138
Range on HMM: 191-252/513
Sequence Identity: 29% (19 aa)

RGIL--YLHTEA-NPPIFHRDIKASNILLDGKNIP--------------------KVADFGLSR
||.   |.|    |  |.|||.| .|||.. ..                      |..||||.|
RGLKLKYCHSHWGN--IIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLAR
Kinase LRR36_k.AA TKL-Unique 24-84 32 3.9e-10 32.1 In-house 1-64 (290) Show / Hide 
Range on Protein: 24-84
Range on HMM: 1-64/290
Sequence Identity: 32% (21 aa)

DARLVGQGGYGKVYRGVLSDGHVVAVKRAEE---GSLQGTHEFYTEIELLSRVH-HRNLLSLVGY
.  ..|.||||.||.|.   |  ||.|. ..    |.. . ||. |. .... | | |.. ..||
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGY
Kinase LRR36_k.AA CAMK 111-161 23 1.9e-09 25.84 In-house 200-283 (425) Show / Hide 
Range on Protein: 111-161
Range on HMM: 200-283/425
Sequence Identity: 23% (20 aa)

IFHRDIKASNILLDGK-----------------NIPKVADFGLSRLAPSPDL----------------DGVTPGHVSTVVKGTP
| |||.|  ||||| .                 |  |..|||...  .. .                 . .|.|.  . . |||
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTP
Kinase LRR36_k.AA CAMK 27-85 14 2.4e-09 25.53 In-house 1-107 (425) Show / Hide 
Range on Protein: 27-85
Range on HMM: 1-107/425
Sequence Identity: 14% (15 aa)

LVGQGGYGKVYRGVLS-DG------------HVVAVKR----------------------------AEEGSLQGTHEFYTEIELLSR-------VHHRNL
  |.|..|||....   ..            . ||.|                             ... . .  .... |||....       ..|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LSLVGYY
..|  .|
IKLYEVY
Kinase LRR36_k.AA MLK 22-83 23 5.3e-09 27.49 In-house 1-76 (291) Show / Hide 
Range on Protein: 22-83
Range on HMM: 1-76/291
Sequence Identity: 23% (18 aa)

FDDARLVGQGGYGKVYRGVLSDGH----VVAVKRAE---EGSLQGT----HEFYTEIELLSRVHHRN----LLSLVG
..  . .| |..|||..|.         .|||||..   . . . |     .| .|...|... |.|       ..|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYG
Kinase LRR36_k.AA TyrKc 22-172 14 8.3e-09 -80.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-172
Range on HMM: 1-280/280
Sequence Identity: 14% (42 aa)

FDDARLVGQGGYGKVYRGVLSDGHVVAVKRAEEGSLQGTHEFYTEIELLSRV--HHRNLLSLVGYYF---------------------------------
    .  | | .|.||.|...    ||||   |..     .|. |.......  || |.. |.|.                                   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

----ATRLRIALGSARGILYLHTEANPPIFHRDIKASNILLDGKNIPKVADFGLSRLAPSP-------DLDGVT---PGH--------------------
    .. | ...  |.|  |||     .. |||. | |.|.. ... |..||||||   .        |   ..    |.                    
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

-----------------------------------VSTVVKG----TPVR-----------------------------VIAFSSQFL
                                   .  | .|     |                                 .   ...
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRR36_k.AA S_TKc 22-172 15 1.1e-07 -64.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-172
Range on HMM: 1-231/231
Sequence Identity: 15% (39 aa)

FDDARLVGQGGYGKVYRGVLSD-GHVVAVKRAEEGSLQGTHEFYTEIELLSRVHHRNLLSLVGYYF-----------AT------RLRIALGS-------
..  |..|.|..||||...  . |..||.|.           .. ||..|.. || |.  | ...             .      ..    |.       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

-----------ARGILYLHTEANPPIFHRDIKASNILLDGKNIPKVADFGLSRLAPSPDLDGVTPG-------HVST-----------------------
           .... |.|   .  | |||.| .|||||     |..||||.|.    .   .||        . ..                       
PEHARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP

----------------VVKGTPVRVIA-------FS-------SQFL
                 ...  ..  .       .         ...
QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase LRR36_k.AA Pkinase_Tyr 26-83 28 1.6e-07 26.06 Pfam 5-71 (270) Show / Hide 
Range on Protein: 26-83
Range on HMM: 5-71/270
Sequence Identity: 28% (19 aa)

RLVGQGGYGKVYRGVLS-----DGHVVAVKRAEEGSLQG---THEFYTEIELLSRV-HHRNLLSLVG
.  |.| .|.||.|..      ..  ||||   ||. .      .|  |.....   || |...|.|
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYG
Kinase LRR36_k.AA CMGC 22-81 15 6e-07 17.89 In-house 1-103 (513) Show / Hide 
Range on Protein: 22-81
Range on HMM: 1-103/513
Sequence Identity: 15% (16 aa)

FDDARLVGQGGYGKVYRGVL---------------SDGHVVAVKRAEEGSLQGTHEF------------YTEIELLSRV-----------------HHRN
..  . .|.| ||.||...                 .. .||.|.  .     ...             . ||..| ..                 || |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LLSL
...|
IVKL
Kinase LRR36_k.AA Pkinase 22-85 24 8e-06 21.6 Pfam 1-69 (293) Show / Hide 
Range on Protein: 22-85
Range on HMM: 1-69/293
Sequence Identity: 24% (17 aa)

FDDARLVGQGGYGKVYRGVLSDG-HVVAVKRAEEGSLQGTHEFYT-----EIELLSRVHHRNLLSLVGYY
.   | .|.|..|.||...  .  ..||||. .    .   . .|     ||... |..| | . | ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWF
Kinase LRR36_k.AA LRRK 22-84 15 1.5e-05 15.59 In-house 1-125 (351) Show / Hide 
Range on Protein: 22-84
Range on HMM: 1-125/351
Sequence Identity: 15% (19 aa)

FDDARLVGQGGYG-KVYRGVLSD---------------------------GHVVAVKRAEEG----------------------------------SLQG
.   ...|.||.| .|||. . .                           .  ||.|  . .                                  ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

THEFYTEIELLSRVHHRNLLSLVGY
 .||  |. ..|. .| |..||.|.
FREFRHEVWIMSHLNHPNIVSLKGF
Kinase LRR36_k.AA Dicty4-Unclassified 25-84 31 3e-05 13.88 In-house 4-66 (263) Show / Hide 
Range on Protein: 25-84
Range on HMM: 4-66/263
Sequence Identity: 31% (20 aa)

ARLVGQGGYGKVYRGVLSDGHVVAVKRAEEGSLQGT----HEFYTEIELLSRVHHRNLLSLVGY
 . .|.|   ||..|.   |  ||||   |.. .       .|  |.|.|  . | ||. . ||
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGY
Kinase LRR36_k.AA HH498 22-51 40 0.000418 8.47 In-house 1-29 (284) Show / Hide 
Range on Protein: 22-51
Range on HMM: 1-29/284
Sequence Identity: 40% (12 aa)

FDDARLVGQGGYGKVYRGVLSDGHVVAVKR
.  .. .| | .||||.|    . .|||||
IEFHEKIGSGSFGKVYKGEWR-NKIVAVKR
Kinase LRR36_k.AA Pkinase_Tyr 113-139 48 0.002207 12.08 Pfam 134-160 (270) Show / Hide 
Range on Protein: 113-139
Range on HMM: 134-160/270
Sequence Identity: 48% (13 aa)

HRDIKASNILLDGKNIPKVADFGLSRL
|||. | |.|.. .|. |..||||.|.
HRDLAARNCLVTENNVVKICDFGLARD
Kinase LRR36_k.AA Dicty4 22-84 25 0.025008 3.77 In-house 1-66 (277) Show / Hide 
Range on Protein: 22-84
Range on HMM: 1-66/277
Sequence Identity: 25% (17 aa)

FDDARLVGQGGYGKVYRGVLSDGHVVAVKRA---EEG-SLQGTHEFYTEIELLSRVHHRNLLSLVGY
 .   . |.|..|.||.|    |  |||| .    .. ..    ||  |.....   | |.. . |.
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGA