Gene LRR36_b (S.moellendorffii)

LRR36_b

Species: S.moellendorffii
Alias: LRR36_b
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR36

Sequence

Name Sequence Type Origin Length Description Download
LRR36_b.AA Protein None 784 None Fasta, JSON
LRR36_b.NA RNA None 2355 None Fasta, JSON
LRR36_b.kin_dom Protein Kinase Domain None 149 None Fasta, JSON

Protein domain

Protein domains of LRR36_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR36_b.AA LRRNT_2 26-63 22 9e-06 21.71 Pfam 1-46 (46) Show / Hide 
Range on Protein: 26-63
Range on HMM: 1-46/46
Sequence Identity: 22% (11 aa)

NTRDVAALQLLFKNWQS-TQ-----LNWT----DYDPCGSSWRGVVCN
.  |..||. . . ... .      ..|.    | |.|   |.|| |.
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCS--WTGVTCD
LRR_1 LRR36_b.AA LRR_1 92-115 44 0.000688 17.96 Pfam 1-26 (26) Show / Hide 
Range on Protein: 92-115
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

DLVALDLSF-N-PQLTGEIPKE-LGRL
 |  ||||  | ..|||.||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_b.AA LRR_1 117-139 40 0.001857 16.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 117-139
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

NLQYLSLQGC---NFYGSVPKE-LGLL
|||.|.|.||   |. |..|.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_b.AA LRR_1 151-167 38 9.12867 3.34 Pfam 7-26 (26) Show / Hide 
Range on Protein: 151-167
Range on HMM: 7-26/26
Sequence Identity: 38% (8 aa)

LNM-N--KLTGSIPPE-LGGF
|.  |  .|||.|||. . ..
LSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_b.AA LRR_1 169-193 28 16.585777 2.42 Pfam 1-26 (26) Show / Hide 
Range on Protein: 169-193
Range on HMM: 1-26/26
Sequence Identity: 28% (8 aa)

NVTWFDIAQ-N--GLTGPLPVSTSVPQN
| .  |.   |   ||| .| | .  . 
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
LRR_1 LRR36_b.AA LRR_1 201-223 29 9.997131 3.2 Pfam 1-26 (26) Show / Hide 
Range on Protein: 201-223
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SVVHMMVEN-N--ALTGEIPVE-YGNF
.  |  . . |   |||.|| .   |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_b.AA LRR_1 225-247 22 0.200565 9.22 Pfam 1-26 (26) Show / Hide 
Range on Protein: 225-247
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

ALEILRVDN-N--RVQGTIPAT-INQI
 |..| ... |  ...|.||   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_b.AA LRR_1 249-270 33 0.001894 16.4 Pfam 1-26 (26) Show / Hide 
Range on Protein: 249-270
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

KLLELHLAN-N--SLVGTLPD--FSAL
.| .|.| . |  .|.|..|.  | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_b.AA LRR_1 297-319 33 1.812571 5.83 Pfam 1-26 (26) Show / Hide 
Range on Protein: 297-319
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLQTLKIDK-G--FLNGTIPDG-LFAL
|||.| ..      | |.||.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_b.AA LRR_1 321-345 27 0.161878 9.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 321-345
Range on HMM: 1-26/26
Sequence Identity: 27% (8 aa)

ALESVSLSN-N--QLSGTVTFPST-VKRL
 |.. .||. |  .|.|.  .|.     |
NLQHLDLSGCNCCNLTGH--IPPSCF-NL
Kinase LRR36_b.AA TKL 614-754 26 2.9e-43 150.06 In-house 1-200 (364) Show / Hide 
Range on Protein: 614-754
Range on HMM: 1-200/364
Sequence Identity: 26% (56 aa)

IGSGGYGKVYKGVLVT---------GEEVAIKKAEEGSMQGSGE---------------------------FKTEIELLSRVHHRNLVGLIGFSYEQGS-
|||||.|.||||..           |..||.||  . ... . .                           .. || ..|| .| |.| ..|.. . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------QMLVYEYMASGS-LRDHLGSEHNCFFYFFECVLMIALDSAKGLAYLHELAS-----PSIIHRDIKSGNILLDENLK------------
             ..|.||.  || | ...          ..  . .||| |.|..|||         | |||||.|| |||.|||..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AKVADFGL
  .|..||||
WCCKICDFGL
Kinase LRR36_b.AA MLK 608-754 28 5.7e-38 129.35 In-house 1-179 (291) Show / Hide 
Range on Protein: 608-754
Range on HMM: 1-179/291
Sequence Identity: 28% (51 aa)

FSSANEIGSGGYGKVYKGVLVTGEE-----VAIKKAE---EGSMQG----SGEFKTEIELLSRVHHRN----LVGLIGFSYEQGSQ-MLVYEYMASGSLR
.     ||||..|||.||.   ...     ||.|...   . ...     . .|..|...|... |.|     . . | . .....  .| ||.. ||| 
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

DHLGSEH-----------NCFFYFFECVLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDE------NLKAKVADFGL
. | ..            | . | .. .. .||. |.|..|||..| . |||||.|| |||.||      ....|..|||.
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGT
Kinase LRR36_b.AA LISK 613-754 35 3.2e-34 108.43 In-house 1-151 (296) Show / Hide 
Range on Protein: 613-754
Range on HMM: 1-151/296
Sequence Identity: 35% (54 aa)

EIGSGGYGKVYKGVLV-TGEEVAIKKAEE-----GSMQGSGEFKTEIELLSRVHHRNLVGLIGFSYE-QGSQMLVYEYMASGSLRDHLGSEHN-CFFYFF
|||.|..|||||| .  ||...|||. ..             .. |.... .  |.| |  .| .|. .|. ..| ||.  | |.. | ..    . .  
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

ECVLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDEN----LKAKVADFGL
.  . |||| |.|..|||   |  ||||| || |.|..||     ..||.|||.
PQRVKIALDIACGMSYLH---SMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGF
Kinase LRR36_b.AA TKL-Unique 610-754 35 6.9e-34 116.95 In-house 1-163 (290) Show / Hide 
Range on Protein: 610-754
Range on HMM: 1-163/290
Sequence Identity: 35% (59 aa)

SANEIGSGGYGKVYKGVLVTGEEVAIKKAEE---GSMQGSGEFKTEIELLSRVH-HRNLVGLIGFSY----EQGSQMLVYEYMASGSLRDHLGS------
  | ||.||||.||||.   |..||||. ..    | . . ||. |. .... | | |.| ..|..      ..   .| ||.  |||.|.|        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--EHNCFFYFFECVLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDEN-----LKAKVADFGL
  . || .  .. .. .|.| |.|. ||| .  | |||||.|| |.|.|.|     ...|..||||
NNNNNCKLN-MQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGL
Kinase LRR36_b.AA Dicty4 608-754 32 2.5e-29 95.13 In-house 1-160 (277) Show / Hide 
Range on Protein: 608-754
Range on HMM: 1-160/277
Sequence Identity: 32% (53 aa)

FSSANEIGSGGYGKVYKGVLVTGEEVAIKKA-----E--EGSMQGSGEFKTEIELLSRVHHRNLVGLIGFSY----EQGSQMLVYEYMASGSLRDHLGS-
    ..||.|..|.||||  . | |||.||.        |  ..   ||. |.....   | |.. . | .     . |. . | ||| .|.|   | . 
INIEQRIGKGSFGEVYKGT-WRGKEVAVKKLNNHNQNFDENMLN---EFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDK

------EHNCFFYFFECVLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDENLKAKVADFGL
      .    .  ..  . .|.| |.|...||.   | |||||.|| |.| |.|...||.||||
PSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGL
Kinase LRR36_b.AA Dicty4-Unclassified 611-770 31 3.3e-29 97.16 In-house 4-171 (263) Show / Hide 
Range on Protein: 611-770
Range on HMM: 4-171/263
Sequence Identity: 31% (55 aa)

ANEIGSGGYGKVYKGVLVTGEEVAIKKAEEGSMQGS----GEFKTEIELLSRVHHRNLVGLIGFSYEQ----GSQMLVYEYMASGSLRDHLG---SEHNC
  .|| |   ||.||.   | .||.||  |.. .       .|| |.|.|  . | ||| . | .          . | | | .| |        || . 
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

FFYFFE-CVLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDENLKAKVADFGLGKEDRAHASITQVKGT
     .  .. .|.| |.|...||   .  .||||||| |||.| .  .|.||||.  .       | . ||
PIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGT
Kinase LRR36_b.AA Pkinase 608-771 29 1.3e-28 102.21 Pfam 1-175 (293) Show / Hide 
Range on Protein: 608-771
Range on HMM: 1-175/293
Sequence Identity: 29% (54 aa)

FSSANEIGSGGYGKVYKGVLVTGEE-VAIKKAEEGSMQGSGEFKT-----EIELLSRVHHRNLVGLIGFSYEQGSQMLVYEYMASG----SLRDHLG-SE
.     ||||..|.|||.. .  .. ||.|. .    . |.. .|     ||... |..| | | |... .. ..  .| ||.  |    .| |..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HNCFFYF-FECVLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDENLKA----KVADFGLGKE--DRAHASITQVKGTL
|.||  |  . . ....  ..||.|.|.    .|||||.|. |||.|.|       |..|||| |          | . ||.
HGCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTP
Kinase LRR36_b.AA TK 608-754 17 4.9e-28 90.46 In-house 1-297 (486) Show / Hide 
Range on Protein: 608-754
Range on HMM: 1-297/486
Sequence Identity: 17% (52 aa)

FSSANEIGSGGYG---KVYKGVLVTG--------------------------EEVAIKKAEEGSMQGSGEFKT-----------------EIELLS--RV
    ...|.| .|   .|||| . ..                          ..||.|   ||. . . ||.                  |.....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHRNLVGLIG-------------FSYEQGSQMLVYEYMASGS----LRDHLGSEHNCFFYFFECVLM---------------------------------
|| |.| |.|             .  .|.  |.| |||. |.    |||.| . .. |.   .|                                    
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

---------------------------------------IALDSAKGLAYLHEL----ASPSIIHRDIKSGNILLDENLK-----------AKVADFGL
                                       .... |.|..|||..      . ..|||.   |.|..||..           .|.|||||
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL
Kinase LRR36_b.AA STE 608-754 25 1.7e-27 94.2 In-house 1-193 (359) Show / Hide 
Range on Protein: 608-754
Range on HMM: 1-193/359
Sequence Identity: 25% (52 aa)

FSSANEIGSGGYGKVYKGVLV----------------TGEEVAIKKAEEGSMQG-----------------SGEFKTEIELLSRVH--HRNLVGLIGFSY
.    .||.|..|.|||.. .                ||| .|||. .  . .                    ... ||..... .  | | |  .|  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EQG-------SQMLVYEYMASGSLRDHLGSEHNCFF----------YFFECVL-MIALDSAKG-LAYLHELASPSIIHRDIKSGNILLDENLKAKVADFG
  |       .  .. |||. |||.| . . . |..          .| | ..  |. .  || |.|||..    |||||||..||||     .| .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

L
.
V
Kinase LRR36_b.AA UTK 608-754 25 5.2e-26 85.97 In-house 1-174 (296) Show / Hide 
Range on Protein: 608-754
Range on HMM: 1-174/296
Sequence Identity: 25% (46 aa)

FSSANEIGSGGYGKVYKGVLVT-----GE-EVAIKKAEEGSM-QGSGE----FKTEIE---LLSRVH-HRNLVGLIGFSYEQGSQMLVYEYMASGSLRDH
    ...|.| .| |.|. ...     .|  ||.|.. .... | . |    |  |     .....| |.|...|.|    ..  |.|.|||. |.||. 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LGSEHN----CFFYFFEC-VLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDEN-------LKAKVADFG---L
| . .     | ... ..  |  |.| | |..|||.     ..|||.   |.|....       ...|.||||   .
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG---FVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGM
Kinase LRR36_b.AA IRAK 608-693 33 3.5e-24 82.7 In-house 1-94 (317) Show / Hide 
Range on Protein: 608-693
Range on HMM: 1-94/317
Sequence Identity: 33% (32 aa)

FSSANEIGSGGYGKVYKGVLVTGEE--VAIK--KAEEGSMQGSGE--FKT---EIELLSRVHHRNLVGLIGFSYEQGSQMLVYEYMASGSLRDHL
|. .| ||.||.| ||.|... ...  .|.|  |... . ... .  | .   |.....| .| |.| | |...| .   |||.||. |||.| |
FHKDNRIGEGGFGCVYRGQWK-NTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRL
Kinase LRR36_b.AA Pkinase_Tyr 608-693 30 1e-22 77.59 Pfam 1-98 (270) Show / Hide 
Range on Protein: 608-693
Range on HMM: 1-98/270
Sequence Identity: 30% (30 aa)

FSSANEIGSGGYGKVYKGVLV-----TGEEVAIKKAEEGSMQG---SGEFKTEIELLSRV-HHRNLVGLIGFSY-EQGS--QMLVYEYMASGSLRDHL
 .   ..|.| .|.||||..      |. .||.|.  ||.|.    . .|  |.....   || |.| |.|  . ....   ..| |||. |.|.|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL
Kinase LRR36_b.AA IRAK 708-754 45 1.4e-17 59.04 In-house 112-159 (317) Show / Hide 
Range on Protein: 708-754
Range on HMM: 112-159/317
Sequence Identity: 45% (22 aa)

LMIALDSAKGLAYLHELASP-SIIHRDIKSGNILLDENLKAKVADFGL
..|.. .|.|. .||.. .  .|||.|||| |||||... .| .||||
CSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGL
Kinase LRR36_b.AA TyrKc 608-783 18 1.6e-13 -4.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 608-783
Range on HMM: 1-280/280
Sequence Identity: 18% (53 aa)

FSSANEIGSGGYGKVYKGVLVTGEEVAIKKAEEGSMQGSGEFKTEIELLSRV--HHRNLVGLIGFSYEQ-------GSQMLVYEYMASGSLRDHL-GSEH
 .   ..|.| .|.||||..   ..||.|.  |..     .|  |.......  || |.| |.|   .|       .  |.| |||. |.|.|.|  ...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

NCFFYFFECVLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDENLKAKVADFGL---GKED----------------RAH-----------------
.      .  | .... |.| .|||.     .||||.   |.|..||. .|..||||   ...|                 ..                 
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

--------------------------------ASITQVKGTLVSK-------N------------------------------FFFLVFVL
                                 | ..|   . .        |                              |  ..  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRR36_b.AA S_TKc 608-784 20 1.5e-11 -7.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 608-784
Range on HMM: 1-231/231
Sequence Identity: 20% (52 aa)

FSSANEIGSGGYGKVYKGVLVT-GEEVAIKKAEEGSMQGSGEFKTEIELLSRVHHRNLVGLIGFSYEQGSQMLVYEYMAS--GSLRDHLGSEHN---CFF
.   ..||.|..|||||.. .  |..||||.           .. ||..|.. || |.| |... .. ..  .| ||.    |.|.|.. .      .| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

YFFECVLMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDENLKAKVADFGLGKE------------------DR-----------------------A
.    .  ..   ...|.|.|..    |||||.|  ||||||    |..|||| ..                  ..                        
FPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFPQ

HASITQVKGTLVSKNFF------------------FLV-------FVLF
.. . .. |   |. .                    |           |
MQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase LRR36_b.AA Pkinase_Tyr 708-754 40 1.3e-08 29.76 Pfam 114-157 (270) Show / Hide 
Range on Protein: 708-754
Range on HMM: 114-157/270
Sequence Identity: 40% (19 aa)

LMIALDSAKGLAYLHELASPSIIHRDIKSGNILLDENLKAKVADFGL
| .... |||..||..     .||||.   |.|..||...|..||||
LQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGL