Gene LRR36_h (S.moellendorffii)

LRR36_h

Species: S.moellendorffii
Alias: LRR36_h
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR36

Sequence

Name Sequence Type Origin Length Description Download
LRR36_h.AA Protein None 923 None Fasta, JSON
LRR36_h.NA RNA None 2772 None Fasta, JSON
LRR36_h.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of LRR36_h.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR36_h.AA LRRNT_2 26-62 23 8e-06 21.79 Pfam 1-46 (46) Show / Hide 
Range on Protein: 26-62
Range on HMM: 1-46/46
Sequence Identity: 23% (11 aa)

NPADTAALRAVRAGWTS-SN-----LNWNGD----DPCGGWQGIGCE
.. |..|| | ...... ..     ..|| .    |.|  | |. | 
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCS-WTGVTCD
LRR_1 LRR36_h.AA LRR_1 67-89 29 15.849203 2.49 Pfam 1-26 (26) Show / Hide 
Range on Protein: 67-89
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

NVTSLDLGDF---RLGGRLLPA-IGDL
| ..|||...   .| | . |  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_h.AA LRR_1 91-114 37 0.010934 13.7 Pfam 1-26 (26) Show / Hide 
Range on Protein: 91-114
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLRTLILAF-N-PLITGLIPSE-LGRL
||..| |   | . .|| ||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_h.AA LRR_1 116-138 40 0.037552 11.8 Pfam 1-26 (26) Show / Hide 
Range on Protein: 116-138
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

NLEFLGLNS-N--RLDGSIPPE-LGLL
||. | |.. |  .| |.|||. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_h.AA LRR_1 140-159 43 1.293155 6.35 Pfam 1-23 (26) Show / Hide 
Range on Protein: 140-159
Range on HMM: 1-23/26
Sequence Identity: 43% (10 aa)

NCTWFDLSE-N--NLSGELPVSS
| .  |||  |  ||.|..| |.
NLQHLDLSGCNCCNLTGHIPPSC
LRR_1 LRR36_h.AA LRR_1 171-193 22 2.524152 5.32 Pfam 1-26 (26) Show / Hide 
Range on Protein: 171-193
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

SAIHFHLNN-N--SFVGRVPEE-ISVL
.  | .|.. |  ...| .|.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_h.AA LRR_1 195-217 33 0.131504 9.87 Pfam 1-26 (26) Show / Hide 
Range on Protein: 195-217
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLIHFLVDS-N--SMSGEIPAA-LANL
|| |  ... |  ...|.||   . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_h.AA LRR_1 219-240 29 0.00331 15.54 Pfam 1-26 (26) Show / Hide 
Range on Protein: 219-240
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLEILRLDN-N--NFSGPFPN--ITRL
.|..| |.. |  |..| .|.  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_h.AA LRR_1 243-263 18 0.023527 12.52 Pfam 1-26 (26) Show / Hide 
Range on Protein: 243-263
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

TLHEIHIRN-N--SFT-SFPD--ISSL
.| ...... |  ..| ..|.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_h.AA LRR_1 289-316 33 0.971773 6.79 Pfam 1-26 (26) Show / Hide 
Range on Protein: 289-316
Range on HMM: 1-26/26
Sequence Identity: 33% (11 aa)

NLQSLELDG-S--NLSGDPSALLLIST--LETL
|||.| |.|    ||.|.      |.   .  |
NLQHLDLSGCNCCNLTGH------IPPSCF-NL
LRR_1 LRR36_h.AA LRR_1 335-379 11 0.693292 7.31 Pfam 1-26 (26) Show / Hide 
Range on Protein: 335-379
Range on HMM: 1-26/26
Sequence Identity: 11% (6 aa)

SLTSIDLAN-N--RI-PEVSRAPPSSSYSVTLGGNPACNTPNLPS--YINC
.|...|| . |  .. ..                        .|.    |.
NLQHLDLSGCNCCNLTGH------------------------IPPSCF-NL
Kinase LRR36_h.AA TKL 608-869 23 1.6e-70 240.6 In-house 1-364 (364) Show / Hide 
Range on Protein: 608-869
Range on HMM: 1-364/364
Sequence Identity: 23% (89 aa)

IGVGGYGKVYKGFLLT---------GEVVAIKRAQAGSMQGA---------------------------HEFKTEIELLSRLHHKNLVELVGFCFEHGE-
|| ||.|.|||| .           |..||.|.    ...                              ... || ..|||.| |.| ..|.|.. .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------QMLVYEYMAGGSIHDHLMDQSKVFSWNKRLEIAIGSARGLSYLHELAN-----PPIIHRDIKSSNILLDEMFV--------------A
             ..|.||. ||| ...|        |..|. .|.. |||..|||         |||||||.||.|||.|| .               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVADLGLSKVSMADEGKTHVSTQ----------------VKGTLGYLDPEYYMTN----------------QLTDKSDVYSFGVVLLELLTARPPIENGK
|..|.|||..   ...... .|                 . ||.... ||  . .                . . |.||||||.|| |.|| ..| .. .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

YVVREIR-------TALARGGLEEVIP-----LLDSSLEGYSARDLKRYLSLAMACVEEAAAQRPSMNDIVKEL
|  ....          .  ||   ||      .           .... .|.. | .. . .|||...|.|.|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR36_h.AA IRAK 602-798 37 2.9e-68 233.1 In-house 1-219 (317) Show / Hide 
Range on Protein: 602-798
Range on HMM: 1-219/317
Sequence Identity: 37% (83 aa)

FSSSHEIGVGGYGKVYKGFLLTGE-VVAIK--RAQAGSMQGAHE--FKT---EIELLSRLHHKNLVELVGFCFEHGEQMLVYEYMAGGSIHDHLMDQSK-
|. .. || ||.| ||.| .   . ..|.|  .. | . .. |.  | .   |.....|..|.|.|.| |.|.| ..  |||.||..|| .| |  |   
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-V---FSWNKRLEIAIGSARGLSYLHELA-NPPIIHRDIKSSNILLDEMFVAKVADLGLSKVS-MADEGKTHVS-----TQVKGTLGYLDPEYYM--TNQ
      || .|..|..|.|.|. .||..    ||||.||||.|||||. |..| .| ||   .  | . . ...       |.||. |. ||.    . |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTDKSDVYSFGVVLLELLT
|| |.||||||.||||.||
LTKKTDVYSFGIVLLEVLT
Kinase LRR36_h.AA TKL-Unique 604-798 33 1.5e-47 164.28 In-house 1-223 (290) Show / Hide 
Range on Protein: 604-798
Range on HMM: 1-223/290
Sequence Identity: 33% (76 aa)

SSHEIGVGGYGKVYKGFLLTGEVVAIKRAQA---GSMQGAHEFKTEIELLSRLH-HKNLVELVGFCF----EHGEQMLVYEYMAGGSIHDHLM-------
 .  || ||||.||||    |. ||||.       | .   ||. |. ....|| |.|.| ..|.|.      ..  .| ||. ||| .|.|        
FWNKIGEGGYGQVYKG-KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--DQSKVFSWNKRLEIAIGSARGLSYLHELANPPIIHRDIKSSNILLDEM-----FVAKVADLGLSKVSMAD-EGKTHVS-----TQVKGTLGYLDPEYY
   ... .....|. .||  |.|. ||| .  | |||||.||||.|.|.      . .|..| ||||..  . ....  .     . ..|.. .. ||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

MT--NQLTDKSDVYSFGVVLLELLT
.   .| . ||||||||.|| |..|
RMNFCQYSEKSDVYSFGIVLWEIAT
Kinase LRR36_h.AA TK 602-869 15 2.8e-43 142.46 In-house 1-486 (486) Show / Hide 
Range on Protein: 602-869
Range on HMM: 1-486/486
Sequence Identity: 15% (76 aa)

FSSSHEIGVGGYG---KVYKGFLLTG--------------------------EVVAIKRAQAGSMQGAHEFKT-----------------EIELLS--RL
    ...| | .|   .|||| . ..                          . ||.|   .|. . . ||.                  |.....   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHKNLVELVGFCFEH------------GEQMLVYEYMAGGS----IHDHLMDQSKV--------------------------------------------
||.|.| |.| |...            .  |.| |||..|.     .|.| . ..                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------FSWNKRLEIAIGSARGLSYLHEL----ANPPIIHRDIKSSNILLDEMFV-----------AKVADLGLS
                               ..   .| ..   |.|..|||..      . ..|||.   |.|..|  |           .|.|| |||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-----VSMAD-EGKTHVSTQVKGTLG-------------------------YLDPEYYM---------TNQLTDKSDVYSFGVVLLELLT---ARPP--
.      . .. ...  .... .|| .                         .. ||  .         ..  | ||||.||||.. |..|   . ..  
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

IENGKYVVREIRTALARGGLEEVIPLLDSSLE---------GYSARDL--------------------KRYLSLAMACVEEAAAQRPSMNDIVKEL
. | . ...         ...||. .| . .          ||  |                      . |  | . | .. ...||.. .....|
MSNQDVWKD-------G-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR36_h.AA TyrKc 602-869 23 2.9e-43 150.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 602-869
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FSSSHEIGVGGYGKVYKGFLLTGEVVAIKRAQAGSMQGAHEFKTEIELLSRL--HHKNLVELVGFCFEH-------GEQMLVYEYMAGGSIHDHLMDQSK
 .  ...| | .|.|||| .   . ||.|  ....     .|  |......|  ||.|.| |.| | ..       .  |.| |||..|. .|.| .  .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

VFSWNKRLEIAIGSARGLSYLHELANPPIIHRDIKSSNILLDEMFVAKVADLGLSKVSMAD------EGKTHVST--QVK--GTLGYLDPEYYMTNQLTD
 ... . |....  |.| .|||.    ..||||.   |.|..| ...|..| |||.    |      .   ....  . |    .  . ||  ...  | 
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDVYSFGVVLLELLT--ARPPIE---NGKYVVREIRTALARGGLEEVIPL----LDSSLEGYSARDLKRYLSLAMACVEEAAAQRPSMNDIVKEL
||||.||||.. |..|  . |. .   . .   .|..  . .|.  .  |             . .  .   ..   | .| ...||....|....
KSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMS-------FVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRR36_h.AA MLK 602-802 29 5.5e-42 143.45 In-house 1-235 (291) Show / Hide 
Range on Protein: 602-802
Range on HMM: 1-235/291
Sequence Identity: 29% (70 aa)

FSSSHEIGVGGYGKVYKGFLLTGE----VVAIKRAQ---AGSMQG----AHEFKTEIELLSRLHHKN----LVELVGFCFEHGEQ-MLVYEYMAGGSIHD
.  .. ||.|..|||.||     .    .||.||.      ...     . .|..|...|..| |.|     ....| | ... .  .| ||..||| ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLMDQSK-------------VFSWNKRLEIAIGSARGLSYLHELANPPIIHRDIKSSNILLDE------MFVAKVADLGLSKVSMADEGKTHVSTQVKGT
 | ....             | .    . .|   |||..|||..| .||||||.||.|||.||        ..|..| |.|.     . ... |..  ||
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNA--GT

LGYLDPEYY---MTNQLTDKSDVYSFGVVLLELLTARPP
. .  ||       .. . |.||.|.|||| |.|| . |
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LRR36_h.AA Dicty4 602-798 33 2.5e-41 135.7 In-house 1-212 (277) Show / Hide 
Range on Protein: 602-798
Range on HMM: 1-212/277
Sequence Identity: 33% (73 aa)

FSSSHEIGVGGYGKVYKGFLLTGEVVAIKRA---QAG-SMQGAHEFKTEIELLSRLHHKNLVELVGFCF----EHGEQMLVYEYMAGGSIHDHLMD----
     .|| |..|.||||    |  ||.| .   . . .     ||. |..... . | |.. . | |     . |. . | |||  |. .  | |    
INIEQRIGKGSFGEVYKG-TWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

--QSKVFSWNKRLE---IAIGSARGLSYLHELANPPIIHRDIKSSNILLDEMFVAKVADLGLSKVSMADEGKTH-VSTQVKGTLGYLDPEYYMTNQLTDK
  ||.  .|  ..    .|.  |||. .||.  || |||||.||.|.| |. ...||.|.|||..   .| ..   .| ..|| ..  ||  | .  . |
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMT-ACGTPCWMAPEVMMHQPYNEK

SDVYSFGVVLLELLT
.|||||| || |.||
ADVYSFGIVLWEILT
Kinase LRR36_h.AA Pkinase 602-802 28 4.5e-40 142.76 Pfam 1-211 (293) Show / Hide 
Range on Protein: 602-802
Range on HMM: 1-211/293
Sequence Identity: 28% (63 aa)

FSSSHEIGVGGYGKVYKGFLLTGEV-VAIKRAQAGSMQGAHEFKT-------EIELLSRLHHKNLVELVGFCFEHGEQMLVYEYMAGG----SIHDHLM-
.     || |..|.|||.     .  ||.|.      ..... |        ||... ||.|.| |.| ... ....  .| ||. ||    . .|... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKK---RHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

DQSKVF--SWNKRLEIAIGSARGLSYLHELANPPIIHRDIKSSNILLDEMFVA----KVADLGLSKV-SMADEGKTHVSTQVKGTLGYLDPEYYM-TNQL
.....|  |..    ..   .||| |.|.     |||||.|..|||.|.  .     |..| ||.|. .   . . .  | . ||..|. ||  .  .  
WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

TDKSDVYSFGVVLLELLTARPP
. |.|..|.|..| |.|. |||
GPKVDMWSCGCILYEMLCGRPP
Kinase LRR36_h.AA LISK 607-749 35 1.7e-39 125.82 In-house 1-154 (296) Show / Hide 
Range on Protein: 607-749
Range on HMM: 1-154/296
Sequence Identity: 35% (56 aa)

EIGVGGYGKVYKGFLL-TGEVVAIKRAQA-----GSMQGAHEFKTEIELLSRLHHKNLVELVGFCFE-HGEQMLVYEYMAGGSIHDHLMD---QSKVFSW
||| |..|||||| .. ||.|.|||  .            . .. |.... .| |.| |  .| | .  |. ..| ||. ||  |. | |   ......|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

NKRLEIAIGSARGLSYLHELANPPIIHRDIKSSNILLDEM----FVAKVADLGLSKV
 .|. || . |.|.||||.     ||||| || |.|..|     . .||.|.|. ..
PQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARM
Kinase LRR36_h.AA CZAK 602-805 33 3.8e-37 129.73 In-house 1-224 (279) Show / Hide 
Range on Protein: 602-805
Range on HMM: 1-224/279
Sequence Identity: 33% (77 aa)

FSSSHEIGVGGYGKVYKGFLLTGEVVAIKRAQAGSMQGAHE------FKTEIELLSRLHHKNLVELVGFCFEHG--EQMLVYEYMAGGSIHDHLMDQSKV
.    .|| | .|.|||.    | .||||     .     |      |  |.  .| | | | |  .| | | |   .  | |.| |||    | | .  
LKFGQTIGQGFFGEVYKAY-WRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFY

FSW--NKRLEIAIGSARGLSYLHELANP-PIIHRDIKSSNILLDEMFV-------------AKVADLGLSKVSMADEGKTHVSTQVKGTLGYLDPEYYMT
       .. .||  |||  |||    | ||.|||  |.|||||.                .|..| |||.  |  |. .   ||  | | .  || .  
HKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMM--EQPFEM-TQTMGCLCWMAPECFKG

NQLTDKSDVYSFGVVLLELLTARPPIEN
   | |.|||||| .| ...| . |  |
ENYTEKVDVYSFGMILWCIITCDQPYQN
Kinase LRR36_h.AA LRRK 602-805 26 4.3e-37 128.75 In-house 1-285 (351) Show / Hide 
Range on Protein: 602-805
Range on HMM: 1-285/351
Sequence Identity: 26% (78 aa)

FSSSHEIGVGGYG-KVYKGFLLT---------------------------GEVVAIKRAQAG----------------------------------SMQG
. .  .||.||.| .||.. .                             .. ||||    .                                  ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

AHEFKTEIELLSRLHHKNLVELVGFCFEHGEQMLVYEYMAGGSIHDHLMDQSK--------VFSWNKRLEIAIGSARGLSYLHELANPPIIHRDIKSSNI
 .||  |. ..|.|.| |.| |.|||...   ..| ||.  |. ...| . ..        ..||. .|.||.  |.|. |||  .|||||||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNI

LL---D---------EMFVAKVADLGLSK----VSMADEGKTHVSTQVKGTLGYLDPEYYMTN---QLTDKSDVYSFGVVLLELLTAR-PPIEN
||   .         .  .||.|| |.|     . |.      |   . |. |.. ||    |   . |.|.|.||||..| |||| . .| ..
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMG------VAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDE
Kinase LRR36_h.AA S_TKc 602-873 23 7.7e-37 129.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 602-873
Range on HMM: 1-231/231
Sequence Identity: 23% (66 aa)

FSSSHEIGVGGYGKVYKGFLLT-GEVVAIKRAQAGSMQGAHEFKTEIELLSRLHHKNLVELVGFCFEHGEQMLVYEYMAG--GSIHDHLMDQSKV-----
.    .|| |..|||||.     |..||||.           .. ||..|.. ||.|.| | ... . ..  .| ||. |  |. .|.. .. .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FSWNKRLEIAIGSARGLSYLHELANPPIIHRDIKSSNILLDEMFVAKVADLGLSKVSMADEGKTHVSTQVKGTLGYLDPEYYMTNQLTD-KSDVYSFGVV
|.      ..   ...| |.|.. .  |||||.| .||||||  . |..| ||...           | . ||. |. ||     . .  |.|..|.|..
FPE-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LLELLTARPPIENGKYVVREIRTALARGGLEEVIPLLDSSLEGYSARDLKRYLSLAMACVEEAAAQRPSMNDIVK-----ELESLL
| |.|. .|| .       .. . . . |                    .  ... . | .   ..||.  .. .      .   .
LYEMLCGYPPFP-------QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR36_h.AA Pkinase_Tyr 602-754 29 1e-36 125.01 Pfam 1-165 (270) Show / Hide 
Range on Protein: 602-754
Range on HMM: 1-165/270
Sequence Identity: 29% (50 aa)

FSSSHEIGVGGYGKVYKGFLL-----TGEVVAIKRAQAGSMQGA---HEFKTEIELLSRL-HHKNLVELVGFCFEHGEQ---MLVYEYMAGGSIHDHLMD
 .  ...| | .|.|||| .      |.  ||.|    |.|. .    .|  |..... | ||.|.| |.| | ..||.   ..| |||..|. .|.| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Q---SKVFSWNKRLEIAIGSARGLSYLHELANPPIIHRDIKSSNILLDEMFVAKVADLGLSKVSMADE
.    . ..    |....  |.|..||..     .||||.   |.|..| .|.|..| ||..  . |.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDD
Kinase LRR36_h.AA DRK 608-798 36 4.3e-36 119.74 In-house 7-197 (258) Show / Hide 
Range on Protein: 608-798
Range on HMM: 7-197/258
Sequence Identity: 36% (71 aa)

IGVGGYGKVYKGFLLTGEVVAIKRAQAGSMQ---GAHEFKTEIELLSRLHHKNLVELVGFCFEHGEQMLVYEYMAGGSIHDHLMDQSKVFSWNKRLEIAI
|| |.|| |. |    |  ||.|.. .          ||. ||.|...| | | .   | | .  .   . |||  ||    | |.|   .|  .. ...
IGRGNYGEVFRG-TWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMF

GSARGLSYLHELANPPIIHRDIKSSNILLDEMFVAKVADLGLSKVSMADEGKTHVSTQVKGTLGYLDPEYYMTNQLTDKSDVYSFGVVLLELLT
  |.|. |||   || ||||| || | | || .  |||| |||      . ..   | . || .   ||       | | |||||..|| |..|
DCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT
Kinase LRR36_h.AA DRK 844-871 35 4e-06 16.91 In-house 231-258 (258) Show / Hide 
Range on Protein: 844-871
Range on HMM: 231-258/258
Sequence Identity: 35% (10 aa)

YLSLAMACVEEAAAQRPSMNDIVKELES
|  |   | .|   .|||| .... ||.
YIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase LRR36_h.AA LISK 781-798 50 3.7e-05 12.5 In-house 217-234 (296) Show / Hide 
Range on Protein: 781-798
Range on HMM: 217-234/296
Sequence Identity: 50% (9 aa)

TDKSDVYSFGVVLLELLT
....||.|||.||.|. |
DESCDVFSFGIVLCEIIT
Kinase LRR36_h.AA Dicty4 858-871 37 0.000131 11.49 In-house 262-277 (277) Show / Hide 
Range on Protein: 858-871
Range on HMM: 262-277/277
Sequence Identity: 37% (6 aa)

QRPSMNDIVKE--LES
.|||.. |...  ||.
HRPSFEEIIQRRILEH
Kinase LRR36_h.AA LRRK 843-871 31 0.000449 10.29 In-house 323-351 (351) Show / Hide 
Range on Protein: 843-871
Range on HMM: 323-351/351
Sequence Identity: 31% (9 aa)

RYLSLAMACVEEAAAQRPSMNDIVKELES
.|..| . | ..   .||....||| |..
MYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR36_h.AA Pkinase_Tyr 776-798 47 0.002346 11.99 Pfam 187-209 (270) Show / Hide 
Range on Protein: 776-798
Range on HMM: 187-209/270
Sequence Identity: 47% (11 aa)

MTNQLTDKSDVYSFGVVLLELLT
...  | ||||.||||.. |..|
NYGKFTTKSDVWSFGVLMWEIFT
Kinase LRR36_h.AA MLK 849-869 33 0.003895 6.88 In-house 271-291 (291) Show / Hide 
Range on Protein: 849-869
Range on HMM: 271-291/291
Sequence Identity: 33% (7 aa)

MACVEEAAAQRPSMNDIVKEL
. | .. ...|||.  ||..|
KQCWNQDPHKRPSFRQIVQHL
Kinase LRR36_h.AA IRAK 845-869 24 0.005428 6.64 In-house 293-317 (317) Show / Hide 
Range on Protein: 845-869
Range on HMM: 293-317/317
Sequence Identity: 24% (6 aa)

LSLAMACVEEAAAQRPSMNDIVKEL
...|  |... |. |..|   ...|
CQCACCCGHHRANRRCDMAWVMQQL
Kinase LRR36_h.AA TKL-Unique 858-869 50 0.011435 5.45 In-house 279-290 (290) Show / Hide 
Range on Protein: 858-869
Range on HMM: 279-290/290
Sequence Identity: 50% (6 aa)

QRPSMNDIVKEL
|||| ..|...|
QRPSFDEIIHRL
Kinase LRR36_h.AA LISK 844-869 34 0.102424 1.12 In-house 271-296 (296) Show / Hide 
Range on Protein: 844-869
Range on HMM: 271-296/296
Sequence Identity: 34% (9 aa)

YLSLAMACVEEAAAQRPSMNDIVKEL
.| |.. |..     |||  .||. |
FLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase LRR36_h.AA Pkinase_Tyr 851-869 26 0.14941 5.88 Pfam 252-270 (270) Show / Hide 
Range on Protein: 851-869
Range on HMM: 252-270/270
Sequence Identity: 26% (5 aa)

CVEEAAAQRPSMNDIVKEL
| .. ...||.. .|. .|
CWHYDPEDRPTFSEIHEQL