Gene LRR36_a (S.moellendorffii)

LRR36_a

Species: S.moellendorffii
Alias: LRR36_a
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR36

Sequence

Name Sequence Type Origin Length Description Download
LRR36_a.AA Protein None 878 None Fasta, JSON
LRR36_a.NA RNA None 2637 None Fasta, JSON
LRR36_a.kin_dom Protein Kinase Domain None 205 None Fasta, JSON

Protein domain

Protein domains of LRR36_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 LRR36_a.AA LRR_1 31-53 33 0.002907 15.74 Pfam 1-26 (26) Show / Hide 
Range on Protein: 31-53
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLVRLSLQNC---GFNGSIPRE-IGSL
|| .|.|..|    . |.|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_a.AA LRR_1 55-77 40 0.399208 8.16 Pfam 1-26 (26) Show / Hide 
Range on Protein: 55-77
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ALSFLALNG-N--FLSGRIPPT-IGLL
 |  | |.| |   |.| |||  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_a.AA LRR_1 79-102 37 1.453492 6.17 Pfam 1-26 (26) Show / Hide 
Range on Protein: 79-102
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLDWCDLSN-N--ALDGELPVSSFGDT
.|   |||. |   | |..| |.|   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_a.AA LRR_1 109-131 33 0.035191 11.9 Pfam 1-26 (26) Show / Hide 
Range on Protein: 109-131
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

VLRHMHLNN-N--NLSGAIPAA-LSTM
 |.| .|.. |  ||.| ||   .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_a.AA LRR_1 133-155 44 0.002536 15.95 Pfam 1-26 (26) Show / Hide 
Range on Protein: 133-155
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

KLFHLLLDN-N--NFSGAIPPE-IGNL
.| || |.. |  |..| |||. . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_a.AA LRR_1 157-179 25 0.013724 13.35 Pfam 1-26 (26) Show / Hide 
Range on Protein: 157-179
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

QLRILRLDN-N--KLEGPVPET-ISRM
.|..| |.. |  .|.| .|.  .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_a.AA LRR_1 181-202 25 0.337189 8.42 Pfam 1-26 (26) Show / Hide 
Range on Protein: 181-202
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

LLLELHLTN-N--PLNGSLPD--LSAV
 | .|.| . |  .| |..|.  . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR36_a.AA LRR_1 229-251 29 5.155807 4.22 Pfam 1-26 (26) Show / Hide 
Range on Protein: 229-251
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

KLKTLEFFK-G--NLVGQIPEE-LFSL
.|..| .      ||.|.||.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR36_a.AA IRAK 525-797 29 4.5e-77 262.37 In-house 1-317 (317) Show / Hide 
Range on Protein: 525-797
Range on HMM: 1-317/317
Sequence Identity: 29% (96 aa)

FSSNHLIGVGGYGKVYKGQLHTGE-LVAIK--RAEKESLQGL--EEFRT---EIELFSRLHHKNLVNLIGFCTDDGQQMLVYEFMPNRTLRDHLYASNTA
|. ...|| ||.| ||.||..  .  .|.|  ...... ..   ..|..   |... .|..|.|.| | |.||. ..  |||..||| .|.| | . ...
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

EQ--ALNWKTRLSIALGSAKGLEYLHELA-DPPIIHRDVKSSNILLDENLVAKVADLGLSKLA-PTCSDEKTYS----SVQVKGTLGYLDPEYYA--YHQ
    .| | .|.||..|.|.|...||..    ||||.|.||.|||||.....| .| ||     |. . ||. .       |.||. |. ||.      |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LSAKSDVYSFGVVLIEIITGK-QPIDNGSF------IVKEIKESVAWGGVASLLS----------------------FVDKRLLDKTTVE--QVKKYFRL
|. |.||||||.|| |..||  .  |...       .. ||.|. .     | .|                      |.|.|   .. ..   .|. . .
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGH--LDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHR---MPPCPPNMEKEMCQC

ALQCVEDSGQDRPKMNEVVKKL
|..|..     |..| .|...|
ACCCGHHRANRRCDMAWVMQQL
Kinase LRR36_a.AA TKL 531-797 23 1.5e-70 240.74 In-house 1-364 (364) Show / Hide 
Range on Protein: 531-797
Range on HMM: 1-364/364
Sequence Identity: 23% (87 aa)

IGVGGYGKVYKGQLHT---------GELVAIKRAEKESLQGL---------------------------EEFRTEIELFSRLHHKNLVNLIG--------
|| ||.|.||||...          |. ||.|.  ... .                             .... || . |||.| |.| ..|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-FCTD----DGQQMLVYEFMPNRTLRDHLYASNTAEQALNWKTRLSIALGSAKGLEYLHELAD-----PPIIHRDVKSSNILLDENLV------------
 .| .    .|| ..|.|..|. .|...|           |  |...||. |.|..|||         ||||||| ||.|||.|||.             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AKVADLGLSK-LAPTCSDEKTYSSVQ--------------VKGTLGYLDPEYYAYH----------------QLSAKSDVYSFGVVLIEIITGKQPID
  .|..|.|||. . .. ....| ....              . ||.... ||    .                . | |.||||||.|| ||.|...| .
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

NGSFIVKEIK----ESVAWGGVASLLSFVDKRLLD----KTTVEQVKKYFRLALQCVEDSGQDRPKMNEVVKKL
.  ..  ..     |  .. .. .|   .. . ..           . . .|. .| .   ..|| ..|..|.|
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR36_a.AA TKL-Unique 529-729 34 1.9e-51 177.22 In-house 3-233 (290) Show / Hide 
Range on Protein: 529-729
Range on HMM: 3-233/290
Sequence Identity: 34% (81 aa)

HLIGVGGYGKVYKGQLHTGELVAIKRAEKESLQGLE---EFRTEIELFSRLH-HKNLVNLIGFCT----DDGQQMLVYEFMPNRTLRDHLY------ASN
 .|| ||||.||||  . |. ||||. ...... .|   ||. |. . ..|| |.|.| ..|.|.    . ..  .| |..|  .|.|.|         |
NKIGEGGYGQVYKG-KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

TAEQALNWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNILLDEN-----LVAKVADLGLSKLAPTCSDEKTYSS-----VQVKGTLGYLDPEYYAY
  .  ||.. |...|.  |.|..||| .  | ||||| ||||.|.|.|     . .|..| ||||.. . .....  .       ..|.. .. ||    
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--HQLSAKSDVYSFGVVLIEIITGKQ------P
   | | ||||||||.||.||.|.|.      |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR36_a.AA TK 525-729 18 9e-44 144.14 In-house 1-394 (486) Show / Hide 
Range on Protein: 525-729
Range on HMM: 1-394/486
Sequence Identity: 18% (75 aa)

FSSNHLIGVGGYG---KVYKGQLHTG--------------------------ELVAIKRAEKESLQGLEEFRT-----------------EIELFS--RL
    . .| | .|   .||||.....                          . ||.|   ... .  |||.                  |.....   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHKNLVNLIGFCTDD------------GQQMLVYEFMPNRT----LRDHLYASNTAEQA-----------------------------------------
||.|.|.|.| ||..            .  |.| |.||.      |||.| ..   .|                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNWKTRLSIALGSAKGLEYLHEL----ADPPIIHRDVKSSNILLDENLV-----------AKVADLGLS
                               |. ...| ...  |.|.||||..      . ..|||.   |.|..||.|           .|.|| |||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-----LAPTCSDEKTYSSVQVKGTLG-------------------------YLDPEYYA---------YHQLSAKSDVYSFGVVLIEIIT-GKQP
.     ||    ... | ... .|| .                         .. ||  .         |.  . ||||.||||.. || | |..|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase LRR36_a.AA Pkinase 525-729 26 2.2e-43 154.49 Pfam 1-211 (293) Show / Hide 
Range on Protein: 525-729
Range on HMM: 1-211/293
Sequence Identity: 26% (59 aa)

FSSNHLIGVGGYGKVYKGQLHTGEL-VAIKRAEKESLQGLEE---FR-TEIELFSRLHHKNLVNLIGFCTDDGQQMLVYEFMPNR----TLRDHLYASNT
.     || |..|.|||.. .  .  ||.|. .|..    ..   .| .||..  ||.|.| | |.....|..   .| |....      | |.. .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

AEQAL--NWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNILLDENLVA----KVADLGLSKLAPTCSDEKTYSSVQVKGTLGYLDPEYYA-YHQLS
.. ..   ...  ....  ..||||.|.     |||||.|..|||.|.| .     |..| ||.|..      .      . ||..|. ||    .   .
RHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

AKSDVYSFGVVLIEIITGKQP
 |.|..|.|..|.| ..|. |
PKVDMWSCGCILYEMLCGRPP
Kinase LRR36_a.AA TyrKc 525-797 27 9.9e-43 149.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 525-797
Range on HMM: 1-280/280
Sequence Identity: 27% (84 aa)

FSSNHLIGVGGYGKVYKGQLHTGELVAIKRAEKESLQGLEEFRTEIELFSRL--HHKNLVNLIGFCTDD-------GQQMLVYEFMPNRTLRDHL-YASN
 . .. .| | .|.||||..   . ||.|   ...   .|.|. |... ..|  ||.|.|.|.| ||..       .. |.| |.||.  |.|.| .  .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

TAEQALNWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNILLDENLVAKVADLGLSKLAPTC----SDEKTYSS---VQVK--GTLGYLDPEYYAYH
.    |..|. ||...  |.| ||||.    ..||||    |.|..||...|..| |||.           ...|..    . |    .  . ||   |.
K----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

QLSAKSDVYSFGVVLIEIIT-GKQPIDN-GS--FIVKEIKESVAWG-GVASLLS-----FVDKRLLDKTTVEQVKKYFRLALQCVEDSGQDRPKMNEVVK
  . ||||.||||.. || | |.||  .        .|. | |  |       .     |          |.  .. ... .|| .    ||| ..|...
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----------VCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

KL
..
CF
Kinase LRR36_a.AA Dicty4 525-729 33 2.6e-40 132.28 In-house 1-216 (277) Show / Hide 
Range on Protein: 525-729
Range on HMM: 1-216/277
Sequence Identity: 33% (73 aa)

FSSNHLIGVGGYGKVYKGQLHTGELVAIKRA--EKES--LQGLEEFRTEIELFSRLHHKNLVNLIGFCT----DDGQQMLVYEFMPNRTLRDHLYA---S
     .|| |..|.||||    |  ||.| .   ..   .  |.||| |... . . | |.. . | ||      |  . | |.||  .|   | .    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

NTAEQALNWKTRLS---IALGSAKGLEYLHELADPPIIHRDVKSSNILLDENLVAKVADLGLSKLAPTCSDEKT-YSSVQVKGTLGYLDPEYYAYHQLSA
   .  | | ....   .|.  |.|. .||.  .| ||||| ||.|.| |.|...||.|.|||..  . .| |.  ..  ..|| ..  ||  . .    
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMT--ACGTPCWMAPEVMMHQPYNE

KSDVYSFGVVLIEIITGKQP
|.|||||| || || |.. |
KADVYSFGIVLWEILTRQEP
Kinase LRR36_a.AA LRRK 525-742 26 4.3e-40 139.51 In-house 1-304 (351) Show / Hide 
Range on Protein: 525-742
Range on HMM: 1-304/351
Sequence Identity: 26% (81 aa)

FSSNHLIGVGGYG-KVYKGQLHT---------------------------GELVAIKRAEKE----------------------------------SLQG
. .. .||.||.| .||.. .                             .. ||||  ...                                  ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LEEFRTEIELFSRLHHKNLVNLIGFCTDDGQQMLVYEFMPNRTLRDHLYASNTAEQ-----ALNWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNI
. ||| |. . |.|.| |.|.|.||| .    ..| |..|. .| ..| ..   ..      ..| ..| |||  |||.||||  ..||||||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNI

LL---D---------ENLVAKVADLGLSKLAPTCSDEK-TYSSVQVKGTLGYLDPEYYAYH---QLSAKSDVYSFGVVLIEIITGK-QPIDN--------
||   .         .. .||.|| |.| .  .|  .. .  .|   |. |.. ||   |    . . |.|.||||..| |..|.. .| |.        
LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCV---GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQ

-GSFIVKEIKE
  ..| ..|.|
WMEQIEDKIIE
Kinase LRR36_a.AA MLK 525-674 26 1.3e-37 128.03 In-house 1-181 (291) Show / Hide 
Range on Protein: 525-674
Range on HMM: 1-181/291
Sequence Identity: 26% (48 aa)

FSSNHLIGVGGYGKVYKGQLHTGE----LVAIKRAE--KESLQGL-----EEFRTEIELFSRLHHKN----LVNLIGFCTDDGQQ-MLVYEFMPNRTLRD
.   . ||.|..|||.||. .  .     ||.||..  ..   .      ..|..|......| |.|     . . | |......  .| |....  | .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLYASNTAEQ----------ALNWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNILLDE------NLVAKVADLGLSK
 |.. .. .                  ...||  |.|..|||..| .|||||| ||.|||.||      ....|..| |.|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR
Kinase LRR36_a.AA Ciliate-E2 525-742 20 2.7e-37 125.58 In-house 1-302 (365) Show / Hide 
Range on Protein: 525-742
Range on HMM: 1-302/365
Sequence Identity: 20% (65 aa)

FSSNHLIGVGGYGKVYKGQL-HTGELVAIKR--------------------AEKESLQGLEEFRTEIELFSRLH----------------HKNLVNLIGF
.  . .|| |..|.|||..   .....|||.                     .  . ...|..  || .. ...                |.|..... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CT--DDGQQMLVYEFMPNRTLRDHLYASNT--------AEQALNWKTRLSIALGSAK---------------GLEYLHELADPPIIHRDVKSSNILLDEN
    ||    || |.    .|.|... ...        . . ...| .. |    ..               .|||||.     ||||| | .|||.   
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF---

LVAKVADLGLSKLAPTCSDEKTYSSVQVK----------------------------GTLGYLDPEYYAYHQ---------LSAKSDVYSFGVVLIEIIT
   |..|.|||| . ......|.  .| |                            ||.||. || . . .          . |.|..|.||.| | ..
--IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GKQPIDNGSFIVKEIKE
|| |        ..||.
GKPPF------QQQIKQ
Kinase LRR36_a.AA Pkinase_Tyr 525-675 33 2.8e-37 126.87 Pfam 1-160 (270) Show / Hide 
Range on Protein: 525-675
Range on HMM: 1-160/270
Sequence Identity: 33% (55 aa)

FSSNHLIGVGGYGKVYKGQLH-----TGELVAIKRAEKESLQGL----EEFRTEIELFSRL-HHKNLVNLIGFCT-DDGQ--QMLVYEFMPNRTLRDHLY
 . .. .| | .|.|||| ..     |.  ||.|   ||.        |.|  |... . | ||.|.|.|.| || ....   ..| |.||.  |.|.| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

ASNTAEQALNWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNILLDENLVAKVADLGLSKL
.  . .|.|. |. |....  |||.|||..     .||||.   |.|..||.|.|..| ||...
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARD
Kinase LRR36_a.AA TK-Unique 525-725 25 4e-36 122.1 In-house 1-234 (294) Show / Hide 
Range on Protein: 525-725
Range on HMM: 1-234/294
Sequence Identity: 25% (60 aa)

FSSNHLIGVGGYGKVYKGQLHTGE-------LVAIKRAE-KESLQGLEEFRTEIELFSRLH-HKNLVNLIGFCTDDG-QQMLVYEFMPNRTLRDHLYASN
.  . .|| | .| |..|.. ..         ||.|  . .....   .|  ||.... |  |.|.|...| ||... ..|...|..|. .|...|  . 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

TA--EQ--------------------ALNWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNILLDENLVAKVADLGLSKLAPTCSDEKTYSSVQ--V
 |  ..                    ... |. ...| . |.|.|||... .  |.|||. ..|.|| |..|.|..|.|...   |   .. ||. .   
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK-IVHRDLCARNVLLTEDKVCKICDFGMARDVYT---NGVYSMMCSQG

KGTLGYLDPEYYA--YHQL-SAKSDVYSFGVVLIEIIT
.  . .. ||.    ...  . ||||.||||.. || |
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase LRR36_a.AA RIPK 531-729 27 1e-35 119.17 In-house 1-227 (290) Show / Hide 
Range on Protein: 531-729
Range on HMM: 1-227/290
Sequence Identity: 27% (62 aa)

IGVGGYGKVYKGQLHTGELVAIKRAEK-----ESLQG--LEEFRTEIELFSRLHHKNLVNLIGFCTDD-----GQ-QMLVYEFMPNRTLRDHLYASNT-A
.| || |.|.| .  .   ...| . .     . ..    ..   | .   .| ... | . ||| .      .. . .| |.|.|  | . | .     
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

EQALNWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNILLDENLVAKVADLGLSKLAPTC--SDEKT-----YSSVQVK--GTLGYLDPEYYAYHQL
.. . |. |  .    . |  |||   .||||||| | .|||.| |. .|.||.||..   .    ...      ||.   .  ||| |..|| .   . 
HHPDPWPLRCRMIHEISCGMCYLHSM-NPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

SA------KSDVYSFGVVLIEIITGKQP
..      |.|||||..|. |. |.|.|
KPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LRR36_a.AA S_TKc 525-801 22 1e-34 122.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 525-801
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

FSSNHLIGVGGYGKVYKGQLHT-GELVAIKRAEKESLQGLEEFRTEIELFSRLHHKNLVNLIGFCTDDGQQMLVYEFMPN--RTLRDHLYASNT--AEQA
.    .|| |..|||||.. .  |..||||.         | .| ||.. .. ||.|.|.|.... | .   .| |....   .|.|..   ..    . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LNWKTRLSIALGSAKGLEYLHELADPPIIHRDVKSSNILLDENLVAKVADLGLSKLAPTCSDEKTYSSVQVKGTLGYLDPEYYAYHQLSA-KSDVYSFGV
..  .  ...   ...|||.|..    |||||.| .||||||  . |..| ||...              . ||. |. ||     . .  |.|..|.|.
FPE-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

VLIEIITGKQPIDNGSFIVKEIKESVAWGGVASLLSFVDKRLLDKTTVEQVKKYFRLALQCVEDSGQDRPKMNEVVK-----KLEEII
.|.| ..|. | .     .... . .                         .    .  .| .   ..||   |. .     |. . .
ILYEMLCGYPPFP----QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR36_a.AA MLK 706-729 50 6.5e-07 20.16 In-house 212-235 (291) Show / Hide 
Range on Protein: 706-729
Range on HMM: 212-235/291
Sequence Identity: 50% (12 aa)

QLSAKSDVYSFGVVLIEIITGKQP
. | |.||.|.|||| |..|.. |
KYSEKCDVWSWGVVLWEMLTREVP
Kinase LRR36_a.AA Pkinase_Tyr 710-729 66 5e-06 20.92 Pfam 194-214 (270) Show / Hide 
Range on Protein: 710-729
Range on HMM: 194-214/270
Sequence Identity: 66% (14 aa)

KSDVYSFGVVLIEIIT-GKQP
||||.||||.. ||.| |.||
KSDVWSFGVLMWEIFTYGEQP
Kinase LRR36_a.AA TK 772-797 30 0.002233 6.33 In-house 461-486 (486) Show / Hide 
Range on Protein: 772-797
Range on HMM: 461-486/486
Sequence Identity: 30% (8 aa)

YFRLALQCVEDSGQDRPKMNEVVKKL
|..| .|| .   .||| . .....|
YYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR36_a.AA LRRK 785-799 33 0.003138 7.26 In-house 337-351 (351) Show / Hide 
Range on Protein: 785-799
Range on HMM: 337-351/351
Sequence Identity: 33% (5 aa)

QDRPKMNEVVKKLEE
..||.....||.|..
KKRPHFSQIVKRLSQ
Kinase LRR36_a.AA Dicty4 785-799 35 0.005407 6.02 In-house 261-277 (277) Show / Hide 
Range on Protein: 785-799
Range on HMM: 261-277/277
Sequence Identity: 35% (6 aa)

QDRPKMNEVVKK--LEE
| || ..|....  ||.
QHRPSFEEIIQRRILEH
Kinase LRR36_a.AA MLK 778-797 30 0.022833 4.18 In-house 272-291 (291) Show / Hide 
Range on Protein: 778-797
Range on HMM: 272-291/291
Sequence Identity: 30% (6 aa)

QCVEDSGQDRPKMNEVVKKL
|| ..   .||.. ..|..|
QCWNQDPHKRPSFRQIVQHL
Kinase LRR36_a.AA Pkinase_Tyr 785-797 38 7.053746 0.21 Pfam 258-270 (270) Show / Hide 
Range on Protein: 785-797
Range on HMM: 258-270/270
Sequence Identity: 38% (5 aa)

QDRPKMNEVVKKL
.||| . |.. .|
EDRPTFSEIHEQL