Gene LRR7a_a (S.moellendorffii)

LRR7a_a

Species: S.moellendorffii
Alias: LRR7a_a
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR7a

Sequence

Name Sequence Type Origin Length Description Download
LRR7a_a.AA Protein None 1049 None Fasta, JSON
LRR7a_a.NA RNA None 3150 None Fasta, JSON
LRR7a_a.kin_dom Protein Kinase Domain None 207 None Fasta, JSON

Protein domain

Protein domains of LRR7a_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR7a_a.AA LRRNT_2 48-89 45 9e-18 60.64 Pfam 1-46 (46) Show / Hide 
Range on Protein: 48-89
Range on HMM: 1-46/46
Sequence Identity: 45% (21 aa)

LDSDLSALLDFKAGLI--DP-GDRLSSWNPSN-AGAPCRWRGVSCF
...|. |||.||..|   || .. |||||||.  . .|.|.||.| 
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_TYP LRR7a_a.AA LRR_TYP 113-137 24 0.107203 7.8 SMART 1-24 (24) Show / Hide 
Range on Protein: 113-137
Range on HMM: 1-24/24
Sequence Identity: 24% (6 aa)

LGSLDTLSLHSNAFNGSIPDSLSAA
|..| .|.|..|..  ..|. . . 
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 115-137 29 0.28666 8.67 Pfam 1-26 (26) Show / Hide 
Range on Protein: 115-137
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLDTLSLHS-N--AFNGSIPDS-LSAA
.| .|.| . |   . |.||.| . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 163-185 40 9.4e-05 21.03 Pfam 1-26 (26) Show / Hide 
Range on Protein: 163-185
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLQVLNLAN-N--RLTGGIPRE-LGKL
.||.|.| . |  .||| || . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 139-161 33 0.01474 13.24 Pfam 1-26 (26) Show / Hide 
Range on Protein: 139-161
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLRVIYLHN-N--AFDGQIPAS-LAAL
||....| . |   . |.|| | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 185-209 36 0.040204 11.29 SMART 1-24 (24) Show / Hide 
Range on Protein: 185-209
Range on HMM: 1-24/24
Sequence Identity: 36% (9 aa)

LTSLKTLDLSINFLSAGIPSEVSNC
|..|..|||| | |   .|... ..
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 187-209 35 0.049648 11.37 Pfam 1-26 (26) Show / Hide 
Range on Protein: 187-209
Range on HMM: 1-26/26
Sequence Identity: 35% (10 aa)

SLKTLDLSI-N--FLS-AGIPSE-VSNC
.|..||||  |   |.   ||..   |.
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 161-184 36 0.176286 6.03 SMART 1-24 (24) Show / Hide 
Range on Protein: 161-184
Range on HMM: 1-24/24
Sequence Identity: 36% (9 aa)

LQKLQVLNLANNRLTGGIPREL-GK
| .|..|.| ||.||  .|... . 
LPNLRELDLSNNQLT-HLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 211-233 44 0.00026 19.46 Pfam 1-26 (26) Show / Hide 
Range on Protein: 211-233
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

RLLYINLSK-N--RLTGSIPPS-LGEL
.| ...||  |  .|||.|||| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 235-257 40 0.07426 10.75 Pfam 1-26 (26) Show / Hide 
Range on Protein: 235-257
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

LLRKVALGG-N--ELTGMIPSS-LGNC
 |..  |.| |   ||| ||.| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 233-257 32 0.47398 2.51 SMART 1-24 (24) Show / Hide 
Range on Protein: 233-257
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

LGLLRKVALGGNELTGMIPSSLGNC
|. ||.  |..| ||  .|. . ..
LPNLRELDLSNNQLT-HLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 259-281 37 0.038043 11.78 Pfam 1-26 (26) Show / Hide 
Range on Protein: 259-281
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLVSLDLEH-N--LLSGAIPDP-LYQL
.| .||| . |   |.| ||.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 283-305 37 3.294066 4.91 Pfam 1-26 (26) Show / Hide 
Range on Protein: 283-305
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

LLERLFLST-N--MLIGGISPA-LGNF
 |..| ||  |   | | |.|  . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 331-353 48 4.4e-05 22.2 Pfam 1-26 (26) Show / Hide 
Range on Protein: 331-353
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

QLQVLNLSG-N--ALTGNIPPQ-IAGC
.||.|.||| |   |||.|||  . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 329-353 40 0.024585 13.04 SMART 1-24 (24) Show / Hide 
Range on Protein: 329-353
Range on HMM: 1-24/24
Sequence Identity: 40% (10 aa)

LKQLQVLNLSGNALTGNIPPQIAGC
| .|..|.||.|.||  .||.. ..
LPNLRELDLSNNQLT-HLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 307-329 37 45.326462 0.87 Pfam 1-26 (26) Show / Hide 
Range on Protein: 307-329
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

VLSQLFLQD-N--ALGGPIPAS-VGAL
 |  | |.. |   | | || |   .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 379-401 40 0.002227 16.15 Pfam 1-26 (26) Show / Hide 
Range on Protein: 379-401
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

QLANLTLSF-N--NISGSIPPE-LLNC
.|  | ||  |  |..|.|||. . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 355-377 37 0.024782 12.44 Pfam 1-26 (26) Show / Hide 
Range on Protein: 355-377
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

TLQVLDVRV-N--ALNGEIPTE-LGSL
.||.||..  |   | |.|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 377-401 32 0.05826 9.97 SMART 1-24 (24) Show / Hide 
Range on Protein: 377-401
Range on HMM: 1-24/24
Sequence Identity: 32% (8 aa)

LSQLANLTLSFNNISGSIPPELLNC
|..|  | ||.|..  ..||.....
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 427-449 48 0.000313 19.17 Pfam 1-26 (26) Show / Hide 
Range on Protein: 427-449
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

GLQILNLRG-N--NLSGEIPSS-LLNI
 ||.|.|.| |  ||.|.||.| . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 403-425 40 0.000324 19.12 Pfam 1-26 (26) Show / Hide 
Range on Protein: 403-425
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLQILRLQG-N--KLSGKLPDS-WNSL
.||.| |.| |  .|.|..|.|   .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 425-449 28 0.131243 7.08 SMART 1-24 (24) Show / Hide 
Range on Protein: 425-449
Range on HMM: 1-24/24
Sequence Identity: 28% (7 aa)

LTGLQILNLRGNNLSGEIPSSLLNI
|. |. |.| .|.|  ..|. ... 
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 475-497 40 0.000162 20.19 Pfam 1-26 (26) Show / Hide 
Range on Protein: 475-497
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ELQSLSLSH-N--SLEKSIPPE-IGNC
 ||.|.||. |  .|...|||. . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 473-497 36 0.00044 20.81 SMART 1-24 (24) Show / Hide 
Range on Protein: 473-497
Range on HMM: 1-24/24
Sequence Identity: 36% (9 aa)

LQELQSLSLSHNSLEKSIPPEIGNC
| .|..|.||.| | ...||.. ..
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 451-473 33 0.002504 15.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 451-473
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLKRLSLSY-N--SLSGNVPLT-IGRL
.|..|.||. |  .|.|..|   .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 523-545 33 0.000739 17.85 Pfam 1-26 (26) Show / Hide 
Range on Protein: 523-545
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

KLQRLQLRD-N--KLSGEIPET-LIGC
.||.| |.. |  .|.|.||.  . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 521-545 28 0.052065 10.37 SMART 1-24 (24) Show / Hide 
Range on Protein: 521-545
Range on HMM: 1-24/24
Sequence Identity: 28% (7 aa)

LSKLQRLQLRDNKLSGEIPETLIGC
|..|..| | .|.|  ..|. . ..
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 499-521 37 0.359812 8.32 Pfam 1-26 (26) Show / Hide 
Range on Protein: 499-521
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLAVLEASY-N--RLDGPLPPE-IGYL
|| .|  |. |  .| | .||. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 547-569 33 0.000307 19.2 Pfam 1-26 (26) Show / Hide 
Range on Protein: 547-569
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLTYLHIGN-N--RLSGTIPVL-LGGL
||..|.... |  .|.|.||   . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR7a_a.AA LRR_1 619-638 42 0.001369 16.9 Pfam 1-26 (26) Show / Hide 
Range on Protein: 619-638
Range on HMM: 1-26/26
Sequence Identity: 42% (11 aa)

NLRSLNVSY-N--HLQGEIPP---AL
||..|..|. |  .|.|.|||   .|
NLQHLDLSGCNCCNLTGHIPPSCFNL
LRR_1 LRR7a_a.AA LRR_1 595-617 48 0.01221 13.53 Pfam 1-26 (26) Show / Hide 
Range on Protein: 595-617
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

NLQALDVSV-N--SLTGPVPSF-LANL
||| ||.|  |  .||| .|.  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 617-641 40 0.021848 13.46 SMART 1-24 (24) Show / Hide 
Range on Protein: 617-641
Range on HMM: 1-24/24
Sequence Identity: 40% (10 aa)

LENLRSLNVSYNHLQGEIPPALSKK
| |||.|. |.|.|  ..|| .   
LPNLRELDLSNNQL-THLPPGAFQG
LRR_1 LRR7a_a.AA LRR_1 571-593 40 0.033409 11.98 Pfam 1-26 (26) Show / Hide 
Range on Protein: 571-593
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

QMQQIRLEN-N--HLTGGIPAS-FSAL
. | . | . |  .||| || | | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRR7a_a.AA LRR_TYP 593-616 41 0.959354 0.0 SMART 1-24 (24) Show / Hide 
Range on Protein: 593-616
Range on HMM: 1-24/24
Sequence Identity: 41% (10 aa)

LVNLQALDVSVNSLTGPVPSFLAN
|.||. || | | ||   |  ...
LPNLRELDLSNNQLTHLPPGAFQG
Kinase LRR7a_a.AA TKL 749-949 19 1.5e-33 117.78 In-house 1-288 (364) Show / Hide 
Range on Protein: 749-949
Range on HMM: 1-288/364
Sequence Identity: 19% (58 aa)

LSRTRFGIVFKACLED---------GSVLSVKRLPDGSIDE----------------------------PQFRGEAERLGSLKHKNLLVLRGYYYSADV-
. . .||.|.|. .           | .  ||...  . ||                             ... |.  . .|.| |.. . ||  . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KLLIYDYMPNGN-LAVLLQQASSQDGSILDWRMRHLIALNIARGLQFLHHACD-----PPVVHGDVRPHNVQFDADFE----------
              ....|.|.|. | .|.            |  |. .|| ||||...||         ||..| |  ..|.  | ...          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----PHISDFGVERLAVTPPADPSTSSS-------------STPAGGSLGYVSPEA--GAT--------------GVASKESDVYGFGILLLELLTGRKP
    . |.|||  |   .   .  |...             . . .|.... .||.  |..              . .|. .||| |||.| |.||...|
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP
Kinase LRR7a_a.AA IRAK 743-951 29 2.2e-28 97.77 In-house 1-225 (317) Show / Hide 
Range on Protein: 743-951
Range on HMM: 1-225/317
Sequence Identity: 29% (67 aa)

FDEDSVLSRTRFGIVFKACLEDGS-VLSVKRLPDGSIDEP-----QFRG---EAERLGSLKHKNLLVLRGYYYSADVKLLIYDYMPNGNLAVLLQQASSQ
|..| ...   || |... .     .  ||.|  .   ..     .|.    | . . .. |.|.. | || .  .   |.|.||||| |   | ..  .
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRL-WCQDG

DGSI--LDWRMRHLIALNIARGLQFLHHAC-DPPVVHGDVRPHNVQFDADFEPHISDFGVERLAVTP-PAD--PSTSS---SSTPAGGSLGYVSPEAGA-
...   | | .|. |.. .|.|.|||| .    |. |||. . |.  |..|.| |.|||   |.  . ||    ....         |.. |  ||.   
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFG---LHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRD

-TGVASKESDVYGFGILLLELLTGRKPAT
 .|  .| .||| ||| |||.|||.....
PQGQLTKKTDVYSFGIVLLEVLTGCRAVY
Kinase LRR7a_a.AA TK 743-949 14 3.4e-19 60.28 In-house 1-394 (486) Show / Hide 
Range on Protein: 743-949
Range on HMM: 1-394/486
Sequence Identity: 14% (58 aa)

FDEDSVLSRTRFG---IVFKACLEDGS--------------------------VLSVKRLPDG-SIDEPQFRG--------------EAERLGSLK----
     .| .  ||    |.|. .....                             || | .| . .. .|.               ||| .  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNLLVLRGYYYSADVK------------LLIYDYMPNGN----LAVLLQQASSQDGS-----------------------------------------
 |.|.. | |.    . |            ...  |||.|.    |   |.. .                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------ILDWRMRHLIALNIARGLQFLHHA----CDPPVVHGDVRPHNVQFDADFE-----------PHISDFGVE
                              .|. . .. ... ||.|...||        . .||.|.  .|.  . .               |.|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

R-----LAVTPPADPSTSSSSTPAGGS------------------LG-----YVSPEAGA---------TGVASKESDVYGFGILLLELLT-GRKP
|     ||   . |    ..|.. .|                    |     . .||. .         .|. . .|||. ||.|. |..| |..|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase LRR7a_a.AA RIPK 817-949 29 1.2e-18 60.1 In-house 83-227 (290) Show / Hide 
Range on Protein: 817-949
Range on HMM: 83-227/290
Sequence Identity: 29% (43 aa)

YMPNGNLAVLLQQASS-QDGSILDWRMRHLIALNIARGLQFLHHACDPPVVHGDVRPHNVQFDADFEPHISDFGVERLAVTP--PADPS-----TSSSST
||.||.|. .|.  .. |.  .. |  |  .   |..| ..||   .||. | |  | |.  |..|   |.|||.     .     |        |. | 
YMENGSLWHFLHTKWPYQHHPDP-WPLRCRMIHEISCGMCYLHSM-NPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSK

PAGGSLGYVSPEAGA------TGVASKESDVYGFGILLLELLTGRKP
. .| | |  ||.        . |.....||| |.|.. |.||...|
NRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LRR7a_a.AA Pkinase 754-947 20 4.4e-16 57.95 Pfam 12-209 (293) Show / Hide 
Range on Protein: 754-947
Range on HMM: 12-209/293
Sequence Identity: 20% (43 aa)

FGIVFKACLEDGSV-LSVKRLPDGSIDEPQFRG-----EAERLGSLKHKNLLVLRGYYYSADVKLLIYDYMPNG----NLAVLLQQASSQDGSI-LDWRM
|| |.|..  . .    ||...  .... . .      |.. . .|.|.| . |...... |   .. .|...|     |. ...   ...|.. .... 
FGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--WRHGCFYFSEWE

RHLIALNIARGLQFLHHACDPPVVHGDVRPHNVQFDADFEP----HISDFGV-ERLAVTPPADPSTSSSSTPAGGSLGYVSPEAGA-TGVASKESDVYGF
   ... |.|||...|      ..| |. | |. .| . ..    .|.|||. . .          .|  |   |...|..||        ....|....
CKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLLELLTGR
|..| |.|.||
GCILYEMLCGR
Kinase LRR7a_a.AA Dicty4-Unclassified 783-949 30 9.8e-15 46.86 In-house 45-207 (263) Show / Hide 
Range on Protein: 783-949
Range on HMM: 45-207/263
Sequence Identity: 30% (52 aa)

FRGEAERLGSLKHKNLLVLRGYYYSA----DVKLLIYDYMPNGNLAVLLQ-QASSQDGSI-LDWRMRHLIALNIARGLQFLHHACDPPVVHGDVRPHNVQ
|. | | |||. | ||. ..||             .   |. |||  .   . | |. .| ||  .   .|. ||.|.|.||      ..| |..  |. 
FKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNIL

FDADFEPHISDFGVERLAVTPPADPSTSSSSTPAGGSLGYVSPEAGATGVASKESDVYGFGILLLELLTGRKP
 | .|   | |||. |         .     |  .|     |||          |||| ....| ||.||  |
MDKHFNIKIADFGISRVI-------DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEP
Kinase LRR7a_a.AA MLK 743-949 21 1.4e-14 47.13 In-house 1-235 (291) Show / Hide 
Range on Protein: 743-949
Range on HMM: 1-235/291
Sequence Identity: 21% (52 aa)

FDEDSVLSRTRFGIVFKACLEDGS----VLSVKRLP--------DGSIDEPQFRGEAERLGSLKHKN----LLVLRGYYYSADV-KLLIYDYMPNGNLAV
...  ..    || |.|.          .. |||           ..... .|. |...|  |.|.|      ...|   .     ...  |...| |. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQW-DFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

LLQQASSQDG---------SILDWRMRHLIALNIARGLQFLHHACDPPVVHGDVRPHNVQFDA------DFEPHISDFGVERLAVTPPADPSTS-SSSTP
.|  |.|.            . |      .||..|||...||    .|..| |  .||.  |.      .    |.|||. |       | ... .  . 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR-------DWHQMCTNMMS

AGGSLGYVSPEA---GATGVASKESDVYGFGILLLELLTGRKP
. |.. . .||.      .  |. .||. .|..| |.||.. |
NAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LRR7a_a.AA TK-Unique 743-945 22 1.6e-14 46.61 In-house 1-234 (294) Show / Hide 
Range on Protein: 743-945
Range on HMM: 1-234/294
Sequence Identity: 22% (54 aa)

FDEDSVLSRTRFGIVFKACLEDGS-------VLSVKRLPDGSIDEP--QFRGEAERLGSLK-HKNLLVLRGYYYSAD-VKLLIYDYMPNGNLAVLLQQAS
.  ..|. ...|| |... .. ..       .  || | |.. |.   .|  |.. . .|. |.|.. . |.  . |   ..|. |.|.|||  .|..  
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

SQ------------------DGSILD-WRMRHLI--ALNIARGLQFLHH--A-CDPPVVHGDVRPHNVQFDADFEPHISDFGVERLAVTPPADPSTSSSS
 .                  |.  ..   .. |.  |  ||.|...|.     .    ||.|.  .|| .  |..  |.|||  |   |   .  .|.. 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI----VHRDLCARNVLLTEDKVCKICDFGMARDVYT---NGVYSMMC

TPAGGSLGYVSPEAGA--TGVA-SKESDVYGFGILLLELLT
.    .. . .||.    .|.. . .|||. ||.|. |..|
SQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase LRR7a_a.AA S_TKc 743-1020 17 2.8e-14 32.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 743-1020
Range on HMM: 1-231/231
Sequence Identity: 17% (50 aa)

FDEDSVLSRTRFGIVFKACLED-GSVLSVKRLPDGSIDEPQFRGEAERLGSLKHKNLLVLRGYYYSADVKLLIYDYMPN--GNLAVLLQQASSQDG-SIL
..   .. .  || |.|.   . | .  .|...       ..| | . | . .|.|.  | ..... |   .. .|...  |.|  ....  .. . . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DWRMRHLIALNIARGLQFLHHACDPPVVHGDVRPHNVQFDADFEPHISDFGVERLAVTPPADPSTSSSSTPAGGSLGYVSPEAGATGVASKESDVYGFGI
.  .   ..  |...|...|      ..| |. | |. .|   .  |.|||. |.              |   |.. |..||    |   ...|.. .|.
PE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGC

LLLELLTGRKPATFSAEEDIVKWVKRQLQGRQAAEMFDPGLLELFDQESSEWEEFLLAVKVALLCTAPDPSDRPSMTEVV----------FM
.| |.|.|. |     .. . | ..                                |      |   ||..||.  |.           ..
ILYEMLCGYPPFP--QMQMMFKKIG-----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR7a_a.AA TyrKc 743-1021 20 1.4e-13 -2.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 743-1021
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

FDEDSVLSRTRFGIVFKACLEDGSVLSVKRLPDGSIDEPQFRGEAERLGSL--KHKNLLVLRGYYYSA-------DVKLLIYDYMPNGNLAVLLQQASSQ
   . .| .  ||.|.|. .    |  || | ...  .  |. ||. . .|  .|.|.. | |.  .        .  ...  |||.|.|   |.    .
ITLGKKLGEGAFGEVYKGTWK-IQVA-VKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

DGSILDWRMRHLIALNIARGLQFLHHACDPPVVHGDVRPHNVQFDADFEPHISDFGVERLAVTPPAD-------PSTSSSSTPAG---GSLGYVSPEAGA
    | ..  . ... ||.| ..||.    ...| |    |.  ....   |||||   |.     |          .....  |     .   .||.  
----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFG---LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

TGVASKESDVYGFGILLLELLT-GRKPATF-----SAEEDIVKWVKRQLQGRQAAE---MFDPGLLELFDQESSEWEEFLLAVKVALLCTAPDPSDRPSM
.|. . .|||. ||... |..| | .|           ......||.    .| ..   |        |     .  . .    . . | . ||.|||..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------F----VCCPDEMYQ--IMKQCWHEDPEDRPTF

TEVVFML
.|..  .
SEIHECF
Kinase LRR7a_a.AA LRRK 816-949 26 2e-13 43.83 In-house 135-282 (351) Show / Hide 
Range on Protein: 816-949
Range on HMM: 135-282/351
Sequence Identity: 26% (42 aa)

DYMPNGNLAVLLQQASSQDG-----SILDWRMRHLIALNIARGLQFLHHACDPPVVHGDVRPHNV---QFD---------ADFEPHISDFGVERLAVTPP
.|.|.|.|  .|. ...|||       ..| ... |||.||.|...||  ..||..| | ...|.    ..         |.   .|.|||  |      
EYAPHGDLYHFLH-NKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF--Q

ADPST-SSSSTPAGGSLGYVSPEAGATG---VASKESDVYGFGILLLELLTGR-KP
.....  . .   .|  |...||    .   . . ..|.| ||..| ||||..  |
CFHMGVAKGC---VGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase LRR7a_a.AA UTK 753-858 24 9.2e-11 33.05 In-house 11-135 (296) Show / Hide 
Range on Protein: 753-858
Range on HMM: 11-135/296
Sequence Identity: 24% (30 aa)

RFGIVFKACLEDGS---VLSVKRLPDGSIDEP---------QFRGEAE---RLGSLK-HKNLLVLRGYYYSADVKLLIYDYMPNGNLAVLLQQASSQ---
.||.|.|| ... |    ........ . ...         .|. ||     .. .. | |.| | |.  .    .... ||.||.|. .|. .. .   
AFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPA

DGSILDWRMRHLIALNIARGLQFLH
.. .|. . |   |..||||.|.||
CPHWLTLHQRLCMAWDIARGMQYLH
Kinase LRR7a_a.AA Dicty4 817-889 39 4e-07 19.98 In-house 83-159 (277) Show / Hide 
Range on Protein: 817-889
Range on HMM: 83-159/277
Sequence Identity: 39% (31 aa)

YMPNGNLAVLLQQ-ASSQDGSI-LDWRMRHL---IALNIARGLQFLHHACDPPVVHGDVRPHNVQFDADFEPHISDFG
||| |||. ||    | |  || |||  .     .|. .|||.. | |.|.| ..| |  .||   |...   ..|||
YMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWL-HCCNPVIIHRDLKSHNLLVDKNWRVKVCDFG
Kinase LRR7a_a.AA Pkinase_Tyr 770-858 25 2e-06 22.59 Pfam 33-128 (270) Show / Hide 
Range on Protein: 770-858
Range on HMM: 33-128/270
Sequence Identity: 25% (25 aa)

VKRLPDGSIDE----PQFRGEAERLGSL-KHKNLLVLRGYYYSADVK---LLIYDYMPNGNLAVLLQQASSQDGSILDWRMRHLIALNIARGLQFLH
|| |..|. .|      |  ||. . .| .|.|.. | |  .. .     ...  |||.|.|   |.. .  |.  |.  .   ... ||.|...|.
VKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLE
Kinase LRR7a_a.AA TK 999-1021 30 3.7e-05 12.39 In-house 464-486 (486) Show / Hide 
Range on Protein: 999-1021
Range on HMM: 464-486/486
Sequence Identity: 30% (7 aa)

VALLCTAPDPSDRPSMTEVVFML
. . | ..||.|||...... .|
LMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR7a_a.AA TKL 998-1021 37 5.6e-05 13.87 In-house 341-364 (364) Show / Hide 
Range on Protein: 998-1021
Range on HMM: 341-364/364
Sequence Identity: 37% (9 aa)

KVALLCTAPDPSDRPSMTEVVFML
| .  | ..||..|||..|..  |
KLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR7a_a.AA Dicty4 1006-1023 40 0.000241 10.59 In-house 258-277 (277) Show / Hide 
Range on Protein: 1006-1023
Range on HMM: 258-277/277
Sequence Identity: 40% (8 aa)

PDPSDRPSMTEVVFM--LEG
.||. |||. |...   || 
HDPQHRPSFEEIIQRRILEH
Kinase LRR7a_a.AA Dicty4 931-949 57 0.001114 8.34 In-house 198-216 (277) Show / Hide 
Range on Protein: 931-949
Range on HMM: 198-216/277
Sequence Identity: 57% (11 aa)

SDVYGFGILLLELLTGRKP
.||| |||.| |.||.  |
ADVYSFGIVLWEILTRQEP
Kinase LRR7a_a.AA TK-Unique 1003-1021 31 0.001249 8.53 In-house 276-294 (294) Show / Hide 
Range on Protein: 1003-1021
Range on HMM: 276-294/294
Sequence Identity: 31% (6 aa)

CTAPDPSDRPSMTEVVFML
|.  .|..||| ......|
CWQWEPEERPSFRQIKHRL
Kinase LRR7a_a.AA LRRK 1002-1023 31 0.00709 5.99 In-house 330-351 (351) Show / Hide 
Range on Protein: 1002-1023
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

LCTAPDPSDRPSMTEVVFMLEG
.| . || .||.....|  |. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR7a_a.AA Pkinase_Tyr 1001-1021 38 0.013372 9.43 Pfam 250-270 (270) Show / Hide 
Range on Protein: 1001-1021
Range on HMM: 250-270/270
Sequence Identity: 38% (8 aa)

LLCTAPDPSDRPSMTEVVFML
..| ..||.|||...|.. .|
KQCWHYDPEDRPTFSEIHEQL
Kinase LRR7a_a.AA MLK 1006-1021 43 0.014626 4.86 In-house 276-291 (291) Show / Hide 
Range on Protein: 1006-1021
Range on HMM: 276-291/291
Sequence Identity: 43% (7 aa)

PDPSDRPSMTEVVFML
.||..|||. ..|  |
QDPHKRPSFRQIVQHL
Kinase LRR7a_a.AA UTK 918-946 33 0.014679 4.58 In-house 207-236 (296) Show / Hide 
Range on Protein: 918-946
Range on HMM: 207-236/296
Sequence Identity: 33% (10 aa)

SPEAGATG-VASKESDVYGFGILLLELLTG
.||| . .   .  |||. ||... |..|.
APEALTHHTRFTTKSDVWSFGVVCWEIWTW
Kinase LRR7a_a.AA Pkinase_Tyr 918-949 39 0.020521 8.8 Pfam 182-214 (270) Show / Hide 
Range on Protein: 918-949
Range on HMM: 182-214/270
Sequence Identity: 39% (13 aa)

SPEAGATGVASKESDVYGFGILLLELLT-GRKP
.||. ..|. . .|||. ||.|. |..| |..|
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase LRR7a_a.AA UTK 998-1021 25 0.046869 2.83 In-house 273-296 (296) Show / Hide 
Range on Protein: 998-1021
Range on HMM: 273-296/296
Sequence Identity: 25% (6 aa)

KVALLCTAPDPSDRPSMTEVVFML
.. . | ..||..||.. ..|  .
RLMHRCWHYDPQERPDFEDLVQQM
Kinase LRR7a_a.AA Dicty4-Unclassified 1003-1021 36 0.052122 2.63 In-house 245-263 (263) Show / Hide 
Range on Protein: 1003-1021
Range on HMM: 245-263/263
Sequence Identity: 36% (7 aa)

CTAPDPSDRPSMTEVVFML
|   ||  ||.| ...  |
CWHNDPNKRPTMNQIIQYL