Gene LRR8_af (S.moellendorffii)
LRR8_af
Species: S.moellendorffii
Alias: LRR8_af
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| LRR8_af.AA | Protein | None | 1075 | None | Fasta, JSON |
| LRR8_af.NA | RNA | None | 3228 | None | Fasta, JSON |
| LRR8_af.kin_dom | Protein Kinase Domain | None | 204 | None | Fasta, JSON |
Protein domains of LRR8_af.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LRRNT_2 | LRR8_af.AA | LRRNT_2 | 55-95 | 43 | 6.5e-16 | 54.6 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 55-95 Range on HMM: 1-46/46 Sequence Identity: 43% (20 aa) ASQDAVNLLALKLDIV--DG-LGYLSDWKDST--TTPCSWTGVTCD ...|. |||.| .. |. .|.||.|..|. ...||||||||| HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD |
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| LRR_1 | LRR8_af.AA | LRR_1 | 99-121 | 25 | 18.520172 | 2.25 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 99-121 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) QISSLNLAS-M--NLTGRVNEN-IGLL .. .|.| . |||| . .. . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 123-145 | 33 | 0.002128 | 16.22 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 123-145 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) SLSVLNLSD-N--SLSGDLPLA-MTSL .| .|.||. | .|.|..| .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 147-169 | 37 | 0.007551 | 14.27 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 147-169 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) NLDTLDISE-N--QFTGRLTNA-IANL || .||.| | ..|| . . . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 171-193 | 25 | 13.3883 | 2.75 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 171-193 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) LLTFFSAHD-N--NFTGPLPSQ-MARL |. . . | |.|| .|. | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 195-217 | 40 | 0.05162 | 11.31 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 195-217 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) DLELLDLAG-S--YFSGSIPPE-YGNL |. ||| | ..|.|||. || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 219-241 | 48 | 0.000115 | 20.71 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 219-241 Range on HMM: 1-26/26 Sequence Identity: 48% (13 aa) KLKTLKLSG-N--LLTGEIPAE-LGNL .|..| ||| | |||.|| . . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 243-265 | 40 | 0.126479 | 9.93 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 243-265 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) ELNHLELGY-N--NYSGGIPRE-FGKL | || |.. | | .| || . | .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 267-289 | 37 | 0.011149 | 13.67 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 267-289 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) QLEYLDMSL-T--GLSGSIPAE-MGNL .|..||.| . |.|.|| . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 291-313 | 25 | 4.498659 | 4.43 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 291-313 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) QCHTVFLYK-N--RLSGILPPE-IGNM . . | | .|.| .||. . |. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 315-337 | 44 | 0.000596 | 18.18 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 315-337 Range on HMM: 1-26/26 Sequence Identity: 44% (12 aa) GLMSLDISD-N--QLSGPIPES-FSRL | .||.|. | .|.| ||.| | | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 339-361 | 37 | 0.231366 | 9.0 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 339-361 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) RLTLLHLMM-N--NLNGSIPEQ-LGEL .|. |.| | || |.||. . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 363-385 | 33 | 0.013114 | 13.42 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 363-385 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) NLETLSVWN-N--LITGTIPPR-LGHT ||..|.. . | .||.|||. . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 411-432 | 37 | 0.025934 | 12.37 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 411-432 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) SLIKLELFS-N--SLTGTIPD--MTNC .| .| | . | .|||.||. |. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 387-410 | 25 | 0.794584 | 7.1 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 387-410 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) SLSWIDVSS-N--LISGEIPRGICKGG .| .|.|. | ..|.|| ... . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 442-456 | 31 | 72.263305 | 0.15 | Pfam | 9-26 (26) | Show / Hide |
Range on Protein: 442-456 Range on HMM: 9-26/26 Sequence Identity: 31% (6 aa) D-N--HLSGPIPAA-FGAM . | .|.| || | .. GCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 458-480 | 37 | 0.020395 | 12.74 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 458-480 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) NLTRLELSK-N--WLNGSIPED-ISAA ||..| || | | |.||.. . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 482-504 | 33 | 0.057646 | 11.14 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 482-504 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) RLAFIDISS-N--RLEGSIPPR-VWSI .| .|.|. | .|.|.|||. . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 506-528 | 37 | 0.75436 | 7.18 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 506-528 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) QLQELHAAG-N--ALSGELTPS-VANA .||.|. | | |.|.. || | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 530-552 | 37 | 0.054373 | 11.23 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 530-552 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) RMLVLDLSE-N--KLQGPIPPE-IVYC . .|||| | .|.| |||. . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 554-576 | 33 | 0.018382 | 12.9 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 554-576 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) KLVTLNLRK-N--TLSGQIPVA-LALL .| .|.|. | |.|.|| . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 578-600 | 40 | 0.039044 | 11.74 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 578-600 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) VLSVLDLSW-N--SLQGRIPAQ-FSQS | .|||| | .|.| || | . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_af.AA | LRR_1 | 602-622 | 30 | 0.166137 | 9.51 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 602-622 Range on HMM: 1-26/26 Sequence Identity: 30% (8 aa) SLEDFNVSY-N--SLSGQLPTS--GL .|. ..|. | .|.|..| | .| NLQHLDLSGCNCCNLTGHIPPSCFNL |
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| Kinase | LRR8_af.AA | TKL | 739-1006 | 21 | 3.8e-62 | 212.77 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 739-1006
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)
IGKGGMGVVYKAEMAS---------GEVVALKQLCNNKESYYTD-------------------------QGFLSEVKVLGGIRHRNIVRLLGYCSNHHT-
||.|| |.|||.. |..|| |.. . .. |. . . |.... .|| |||...||| .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------DMLLYEYMPNGSLSDLLHGQKNSSSLLADWVARYNIAMGVAQGLAYLHHDCF----PHVIIHRDVKSSNILLDHNMD-----------
.. .||.|.||| ..|| | | ..|...|.|..||| . . . ||||| ||.|||.| |.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA
---ARVADFGLAKLIEARES--------------------MSVVAGSYGYIAPEYAYTM----------------KVREKGDIYSYGVVLLELLTGKRPI
. ..||||.. .. ... . . |.... ||| . . || |.||.|.|| |.||..||
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY
EPEFGEGSNIVDWVHSK-LRKGRLVEVLDWSIG----------GCESVREEMLLVLRVAMLCTSRAPRDRPTMRDVVSML
. . . . | . .. ... .. | | |... ..| . .. | . |..||.. .... |
YDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSM---KKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | LRR8_af.AA | IRAK | 734-936 | 35 | 3.3e-55 | 189.75 | In-house | 2-223 (317) | Show / Hide |
Range on Protein: 734-936 Range on HMM: 2-223/317 Sequence Identity: 35% (80 aa) RDKNIIGKGGMGVVYKAEMASGE-VVALKQLCNNKESYYT--DQGFLS---EVKVLGGIRHRNIVRLLGYCSNHHTDMLLYEYMPNGSLSDLLHGQKNSS | ||.|| |.||.... . ..| | | ..... . .| |.. |.||. .|| ||| |.|||. | |.||||||| | |..|... HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC SL--LADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLI---EARESMSV-------VAGSYGYIAPEYAY--TMK .. | | | |. | | |. .|| . |||.|.||.||||| .. . .||||. ...|. .. | |. | .||. . . . PPKPLS-WHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ VREKGDIYSYGVVLLELLTGKRP | |.|| |.||||.||| |. LTKKTDVYSFGIVLLEVLTGCRA |
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| Kinase | LRR8_af.AA | MLK | 733-936 | 29 | 2.2e-49 | 169.45 | In-house | 1-235 (291) | Show / Hide |
Range on Protein: 733-936 Range on HMM: 1-235/291 Sequence Identity: 29% (70 aa) IRDKNIIGKGGMGVVYKAEMASGE----VVALKQLCNNK----ESYYTDQGFLSEVKVLGGIRHRN----IVRLLGYCSNH-HTDMLLYEYMPNGSLSDL |. . .||.|..|.|.|... . .||.|. .. ..| .. | |.. | ..|.| |....| |... . .. ||...|||... IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV LHGQK----------NSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDH------NMDARVADFGLAKLIEARES-MSVVAGSYG |||.. . .. | |.|. .|.|..||| . |. ||||| ||.|||.|. .......|||... . ... | ||.| LHGARSKWMDANHNQK-NDRVYDHDHAMNWALQCARGMHYLHSMA-PKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA YIAPEY---AYTMKVREKGDIYSYGVVLLELLTGKRP . ||| . |. || |..|.|||| |.||.. | WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP |
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| Kinase | LRR8_af.AA | TKL-Unique | 735-936 | 34 | 5e-42 | 145.93 | In-house | 1-233 (290) | Show / Hide |
Range on Protein: 735-936
Range on HMM: 1-233/290
Sequence Identity: 34% (81 aa)
DKNIIGKGGMGVVYKAEMASGEVVALKQLC-NNKESYYTDQGFLSEVKVLGGIR-HRNIVRLLGYCS----NHHTDMLLYEYMPNGSLSDLLH-----GQ
. | || ||.|.|||.. . |. ||.||. |.. | | | .||... .. | |||.. ||| . ||.| ||| |.||
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN
KNSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHN-----MDARVADFGLAKLIE--ARESMS--------VVAGSYGYIAPEY
|.... .. |...| .|||. |||| | ||||| ||||.|.| | . ....||||.|. ... . .. ||. ..|||
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP--IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV
AYT--MKVREKGDIYSYGVVLLELLTGKR------P
. || |.||.|.|| |..|.|. |
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
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| Kinase | LRR8_af.AA | Dicty4-Unclassified | 733-936 | 33 | 4.3e-41 | 138.46 | In-house | 1-207 (263) | Show / Hide |
Range on Protein: 733-936 Range on HMM: 1-207/263 Sequence Identity: 33% (73 aa) IRDKNIIGKGGMGVVYKAEMASGEVVALKQLCNNKESYY--TDQGFLSEVKVLGGIRHRNIVRLLGYCSNH----HTDMLLYEYMPNGSLSDLLH---GQ |. |||| . |.| | || | . || . | |. || .|| | | | |.. ||| | | . | |. | | . | IQIDQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE KNSSSLLAD--WVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLIEARESMSVVAGSYGYIAPEYAYTMKVREKGDIY .. . | | .. .|. .|||...|| .||||.||||||.| . ...||||.. |. | .|| .|| | |.| QQQPIKLDDTLIIK---YAFDIAQGMQHLHT----RNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVY SYGVVLLELLTGKRP ||...| ||.|| | SYAMMLYELATGDEP |
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| Kinase | LRR8_af.AA | Pkinase | 733-934 | 27 | 8.7e-41 | 145.3 | Pfam | 1-209 (293) | Show / Hide |
Range on Protein: 733-934 Range on HMM: 1-209/293 Sequence Identity: 27% (61 aa) IRDKNIIGKGGMGVVYKAEMASGEV-VALKQLCNNKESYYTDQGFLS--EVKVLGGIRHRNIVRLLGYCSNHHTDML-LYEYMPNG----SLSDLLH-GQ .. . .||.|..|.|||. . . ||.|... .|. || . |.... ..| |||||.... . .... ||...| .|.|... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR KNSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDA----RVADFGLAKL--IEARESMSVVAGSYGYIAPEYAY-TMKVRE ... . . .|... ... ...||.|.| |||||.|..|||.|.|.. ...||||||. . . |....|...|.||| . HGCFY-FSEWECK-FYMYQILRGLEYCHSM----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP KGDIYSYGVVLLELLTGK | |..|.|..| |.|.|. KVDMWSCGCILYEMLCGR |
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| Kinase | LRR8_af.AA | Dicty4 | 733-936 | 34 | 4e-38 | 124.86 | In-house | 1-216 (277) | Show / Hide |
Range on Protein: 733-936 Range on HMM: 1-216/277 Sequence Identity: 34% (75 aa) IRDKNIIGKGGMGVVYKAEMASGEVVALKQLCNNKES--YYTDQGFLSEVKVLGGIRHRNIVRLLGYCS----NHHTDMLLYEYMPNGSLSDLLHG--QK | ..||||. | |||. | || | | |... .. . |. ||. .. ||| ||. ..|.| . . . |||| |.| ||| INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE NSSSLLADWVARYN---IAMGVAQGLAYLHH-DCFPHVIIHRDVKSSNILLDHNMDARVADFGLAK----LIEARESMSVVAGSYGYIAPEYAYTMKVRE .| || . .| .|.|...|| .. |||||| ||.|.| | |. . |.||||.. .. .. ..|. .. ||| | QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNP---VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE KGDIYSYGVVLLELLTGKRP | | ||.| || |.||.. | KADVYSFGIVLWEILTRQEP |
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| Kinase | LRR8_af.AA | LISK | 738-936 | 27 | 8.5e-38 | 120.25 | In-house | 1-238 (296) | Show / Hide |
Range on Protein: 738-936 Range on HMM: 1-238/296 Sequence Identity: 27% (67 aa) IIGKGGMGVVYKAEMA-SGEVVALKQLCN-----NKESYYTDQGFLSEVKVLGGIRHRNIVRLLGYCSN-HHTDMLLYEYMPNGSLSDLLHGQKNSSSLL .||||. | ||| . .|.|.|.|.. . |...| .| ||... .||.|||. | | . ... ||. | | ..|. . .. | EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKF--MLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPL ADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHN----MDARVADFGLAKLIEARE---------------------------------- | | .|| ..|.|..||| . ||||| || |.|.. | ..|.|||.|.... .. P-WPQRVKIALDIACGMSYLHSMN----IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQR --SMSVVAGSYGYIAPEYAYTMKVREKGDIYSYGVVLLELLTGKRP .|... |. ||| .. |. |..|.|.||.|. |.... KRRMTIC-GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA |
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| Kinase | LRR8_af.AA | STE | 733-936 | 23 | 2.6e-33 | 114.99 | In-house | 1-267 (359) | Show / Hide |
Range on Protein: 733-936 Range on HMM: 1-267/359 Sequence Identity: 23% (65 aa) IRDKNIIGKGGMGVVYKAEMA----------------SGEVVALKQLCNNKES---------------YYTDQGFLSEVKVLGGIR--HRNIVRLLGYCS .. .||||. |.|||| .||..| ||. .... | .| |.|.. . | |||. .|.. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF NH-------HTDMLLYEYMPNGSLSDLLH---GQKNSSSLL--------ADWVARYNIAMGVAQG-LAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVA . .. . |||..|||.|... | ... .. ...|. |. . .| |.||| |||||.|..|||| . . KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAY--ICRQILKGLLYYLHSHH----IIHRDIKPANILL-----VKLC DFGLAKLIEA-----------------RESMSVVAGSYGYIAPEYAYTMKVR------EKGDIYSYGVVLLELLTGKRP |||... .. . ..|. . ||| .. .| ||.| | ...|..||| | DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP |
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| Kinase | LRR8_af.AA | TK | 733-936 | 15 | 5.3e-33 | 107.4 | In-house | 1-394 (486) | Show / Hide |
Range on Protein: 733-936
Range on HMM: 1-394/486
Sequence Identity: 15% (63 aa)
IRDKNIIGKGGMG---VVYKAEMASG--------------------------EVVALKQLCNNKESYYT-DQG--------------FLSEVKVLGG--I
|. . .|.| | .|||.|. .. . || |.| .. . . ...| |..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
RHRNIVRLLGYCSNHHTD------------MLLYEYMPNGS----LSDLLHGQKN---------------------------------------------
.| |||||.|.|. . . |.. ||||.|. | | |. ..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
---------SSSLLADWVARYN----------------IAMGVAQGLAYLHHDCFPHV---IIHRDVKSSNILLDHNMD-----------ARVADFG---
.. ..| . . . ... .|.|..||| . ..|||. |.|...|. ...||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-----LAKLIEARESMSVVAGSYG---------------------------YIAPEYAY---------TMKVREKGDIYSYGVVLLELLT-GKRP
||. |. .. .. . .. . ||| . | .| |..|.||.. |..| |. |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
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| Kinase | LRR8_af.AA | S_TKc | 733-1013 | 22 | 8.4e-33 | 116.22 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 733-1013 Range on HMM: 1-231/231 Sequence Identity: 22% (66 aa) IRDKNIIGKGGMGVVYKAEMAS-GEVVALKQLCNNKESYYTDQGFLSEVKVLGGIRHRNIVRLLGYCSNHHTDMLLYEYMPN--GSLSDLLHGQKN--SS . ..||||..|.|||. . |..||.|.. . ...|...| .| |||.|.... . . . ||... |.| |... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR SLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLIEARESMSVVAGSYGYIAPEYAYTMKVRE-KGDIYSYGVV . . .||. .. ....|.|.| |||||.| .|||||. ..|||||... . . |. |.||| . | |..| |.. FPFPE-HARFYMYQ-ICCALEYCHSHG----IIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI LLELLTGKRPIEPEFGEGSNIVDWVHSKLRKGRLVEVLDWSIGGCESVREEMLLVLRVAMLCTSRAPRDRPTMRDVVS--MLIEAQPRR | |.|.|. | . . . . . .. . | . |..||| .. ..| . | LYEMLCGYPPFP----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | LRR8_af.AA | Pkinase_Tyr | 733-936 | 26 | 4.5e-27 | 92.33 | Pfam | 1-214 (270) | Show / Hide |
Range on Protein: 733-936 Range on HMM: 1-214/270 Sequence Identity: 26% (60 aa) IRDKNIIGKGGMGVVYKAEMA-----SGEVVALKQLCNNKESYYTDQG-----FLSEVKVLGGI-RHRNIVRLLGYCS-NHHT--DMLLYEYMPNGSLSD |. .|.| |.|||... . || | | .. ..... |..|.|.. . .| |||||.| |. .. ||||.|.| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD LLHGQKNSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLIEARESMSVVAGS-----YGYIAPEYAYTMK |. .. .. . .... .|.|..||. .||||. |.|...|. ....|||||..|. . ..... ||| ..| YLRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN----CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK VREKGDIYSYGVVLLELLT-GKRP .| |..|.||.. |..| |. | FTTKSDVWSFGVLMWEIFTYGEQP |
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| Kinase | LRR8_af.AA | LRRK | 779-936 | 32 | 1.6e-25 | 87.21 | In-house | 107-282 (351) | Show / Hide |
Range on Protein: 779-936 Range on HMM: 107-282/351 Sequence Identity: 32% (59 aa) EVKVLGGIRHRNIVRLLGYCSNHHTDMLLYEYMPNGSLSDLLHGQKNSS-SLLA-D--WVARYNIAMGVAQGLAYLHHDCFPHV--IIHRDVKSSNILL- || .. . .| ||| |.|.| .. .. ||.|.|.|...|| |... . . . | .. ||. .| |..||| | ||||| || |||| EVWIMSHLNHPNIVSLKGFCIHPL--CMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS----HNPPIIHRDLKSPNILLW --D---------HNMDARVADFGLAKLIEARES--MSVVAGSYGYIAPEYAYTM---KVREKGDIYSYGVVLLELLTGK-RP . .. | .||||. . . . . . | |. ||| . || |.||.|..| ||||.. .| SSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP |
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| Kinase | LRR8_af.AA | TyrKc | 733-1006 | 22 | 3.1e-23 | 84.45 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 733-1006 Range on HMM: 1-280/280 Sequence Identity: 22% (69 aa) IRDKNIIGKGGMGVVYKAEMASGEVVALKQLCNNKESYYTDQGFLSEVKVLGGI--RHRNIVRLLGYCSNH-------HTDMLLYEYMPNGSLSDLLHGQ |. . ..| | |.|||... . || | | ... . |..| ... . .| |||||.|.|. . . |.. ||||.|.| | |. ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH KNSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLIEAR-------ESMSV----VA---GSYGYIAPEYA .. . ... .|.| .|||. .|||| |.|...| ....||||.. |. . .. . . ||| RPK----LCMKDLLSFCWQIACGMEYLHSK----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI YTMKVREKGDIYSYGVVLLELLTGKRPIEPEFG------EGSNIVDWVHSKLRKGRLVEVLDWSIGGCESVREEM------LLVLRVAMLCTSRAPRDRP . | .| |..|.||.. |..| . .| | . . .. .| . | . ... . | . .. | . | ||| NYGKFTTKSDVWSFGVCMWEIFT--YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----------P-MSFVCCPDEMYQIMKQCWHEDPEDRP TMRDVVSML |...... . TFSEIHECF |
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| Kinase | LRR8_af.AA | LRRK | 733-763 | 18 | 1.5e-05 | 15.55 | In-house | 1-59 (351) | Show / Hide |
Range on Protein: 733-763 Range on HMM: 1-59/351 Sequence Identity: 18% (11 aa) IRDKNIIGKGGMG-VVYKAEMAS---------------------------GEVVALKQL .. . ||.|| | .||.|.. . .. || |.. LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW |
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| Kinase | LRR8_af.AA | TK | 983-1006 | 29 | 8.7e-05 | 11.13 | In-house | 463-486 (486) | Show / Hide |
Range on Protein: 983-1006 Range on HMM: 463-486/486 Sequence Identity: 29% (7 aa) RVAMLCTSRAPRDRPTMRDVVSML .. . | .. |.||||.......| DLMQQCWHYDPEDRPTFSQLHEQL |
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| Kinase | LRR8_af.AA | LRRK | 986-1008 | 26 | 0.001176 | 8.79 | In-house | 329-351 (351) | Show / Hide |
Range on Protein: 986-1008 Range on HMM: 329-351/351 Sequence Identity: 26% (6 aa) MLCTSRAPRDRPTMRDVVSMLIE ..| . |..||.. ..|. | . QHCWQHDPKKRPHFSQIVKRLSQ |
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| Kinase | LRR8_af.AA | MLK | 993-1006 | 42 | 0.016349 | 4.69 | In-house | 278-291 (291) | Show / Hide |
Range on Protein: 993-1006 Range on HMM: 278-291/291 Sequence Identity: 42% (6 aa) PRDRPTMRDVVSML |..||..| .|. | PHKRPSFRQIVQHL |
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| Kinase | LRR8_af.AA | LISK | 982-1006 | 28 | 0.018168 | 3.6 | In-house | 272-296 (296) | Show / Hide |
Range on Protein: 982-1006 Range on HMM: 272-296/296 Sequence Identity: 28% (7 aa) LRVAMLCTSRAPRDRPTMRDVVSML |.... |.. |..||. ..|. | LDLCFDCCKYDPKNRPSFKEIVQWL |
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| Kinase | LRR8_af.AA | Dicty4-Unclassified | 988-1006 | 36 | 0.024983 | 3.74 | In-house | 245-263 (263) | Show / Hide |
Range on Protein: 988-1006 Range on HMM: 245-263/263 Sequence Identity: 36% (7 aa) CTSRAPRDRPTMRDVVSML | . |. |||| ... | CWHNDPNKRPTMNQIIQYL |
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| Kinase | LRR8_af.AA | Pkinase_Tyr | 993-1006 | 42 | 0.054624 | 7.36 | Pfam | 257-270 (270) | Show / Hide |
Range on Protein: 993-1006 Range on HMM: 257-270/270 Sequence Identity: 42% (6 aa) PRDRPTMRDVVSML | ||||.......| PEDRPTFSEIHEQL |
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